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Urinary markers of pain in children in neonatal intensive care units: a cross-section study 新生儿重症监护室儿童疼痛的尿液标记物:横断面研究
Q2 Medicine Pub Date : 2024-04-11 DOI: 10.36311/jhgd.v34.15783
Cassia Sueli De Oliveira e Souza, Gerson Salay, L. V. De Alcântara Sousa, Beatriz da Costa Aguiar Alves, Glaucia Luciano da Veiga, Thaís Moura Gascón, Fernando Luiz Affonso Fonseca, David Feder
Introduction: Repetitive exposition to pain negatively affects newborns development. Procedural pain in newborn in Neonatal Intensive Care Unit (NICU) triggers a series of physiological, behavioral and hormonal disorders that may set off the impairment of the neurological development in preterm infants, who undergo long periods of hospitalization at a moment of physiological immaturity and fast brain development.Objective: This study aimed not only to observe the pain score in newborns and infants when undergoing painful procedures in neonatal intensive care units but also to analyse urinary IL-8 and cortisol levels at such stressful moments.Methods: Patients were submitted to venipuncture and to other methods of blood collection. Cortisol and IL-8 levels were measured by immunometric assay and chemiluminescence detection. For the collection of data regarding observation of neonatal pain, the Neonatal Infant Pain Scale was used with immediate results. To describe the qualitative variables, absolute and relative frequencies were used. For the quantitative variables with normal distribution, mean, standard deviation, minimum and maximum were used.Results: A total of 81 patients were included: 47 were submitted to venipuncture and 36 to other methods of blood collection. Significance for cortisol can be seen (p=0.04); however, IL-8 levels, when associated with the pain scale, were not sensitive enough (p=0.11).Conclusion: The results showed that cortisol is a better marker for pain than IL-8, and its accumulation in urine may help the detection and interpretation of pain. Conclusion: Based on this information, nurses can step in to reduce the discomfort brought by painful procedures, and thus highlight humanistic practices in nursing assistance.
导言反复遭受疼痛会对新生儿的发育产生负面影响。新生儿重症监护室(NICU)中新生儿的手术疼痛会引发一系列生理、行为和激素紊乱,可能会损害早产儿的神经系统发育:本研究不仅旨在观察新生儿和婴儿在新生儿重症监护室接受疼痛手术时的疼痛评分,还旨在分析在这种紧张时刻尿液中的 IL-8 和皮质醇水平:方法:对患者进行静脉穿刺和其他采血方法。通过免疫测定和化学发光检测法测量皮质醇和 IL-8 的水平。为了收集有关新生儿疼痛观察的数据,使用了新生儿婴儿疼痛量表,结果立竿见影。在描述定性变量时,使用了绝对频率和相对频率。对于正态分布的定量变量,则使用平均值、标准差、最小值和最大值:结果:共纳入 81 名患者:结果:共纳入 81 名患者:47 名采用静脉穿刺采血,36 名采用其他采血方法。皮质醇具有显著性(P=0.04);然而,当 IL-8 水平与疼痛量表相关联时,则不够敏感(P=0.11):结果表明,皮质醇是比 IL-8 更好的疼痛标志物,其在尿液中的累积可能有助于疼痛的检测和解释。结论根据这些信息,护士可以介入减少疼痛程序带来的不适,从而在护理协助中突出人性化实践。
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引用次数: 1
Epidemiological evolution of COVID-19: a three-year perspective on coping with the pandemic in the States of Rio Grande do Sul and Paraná, Southern Region of Brazil COVID-19 的流行病学演变:巴西南部地区南里奥格兰德州和巴拉那州应对大流行病的三年展望
Q2 Medicine Pub Date : 2024-04-11 DOI: 10.36311/jhgd.v34.15776
Daniel Alvarez Estrada, Silvana De Azevedo Brito, Marcelo Ferraz de Campos, Alzira Alves de Siqueira Carvalho
Introduction: The novel Coronavirus disease (COVID-19) is caused by SARS-CoV-2 and represents the agent responsible for a respiratory and metabolic disease with a high fatality rate, remaining a public health problem to this day. There has been an exacerbation of social inequalities experienced in Brazil and worldwide. Notably, the absence of a consolidated and universal healthcare system has contributed to the increased inequalities and survival opportunities for those affected by SARS-CoV-2 infection and manifestation of COVID-19. The southern region has become the second region with the highest number of cases in Brazil.Objective: To avaluate the epidemiological outcomes of incidence, lethality, and mortality among the states of Rio Grande do Sul and Paraná in the southern region of Brazil.Methods: An ecological time-series study was conducted using official secondary data on COVID-19 cases and deaths publicly disclosed by the health departments of the states of Rio Grande do Sul and Paraná. Time series were constructed applying the Prais-Winsten regression model. Statistical analyses were performed using STATA 14.0 software.Results: It was observed that for the state of Rio Grande do Sul, the trends regarding incidence were increasing in 2020 and decreasing in 2021 (p<0.05). Regarding mortality, it increased in 2020 and decreased in 2021 and 2022 (p<0.05). When assessing lethality, a decreasing trend was observed for the entire period (p<0.05). In relation to Paraná, incidence increased in 2020 and over the entire period, while it decreased in 2021 and 2022 (p<0.05). Mortality was stationary in 2020 and decreased in 2021 and 2022 (p<0.05).Conclusion: The COVID-19 pandemic is a serious public health problem in the states of Paraná and Rio Grande do Sul. Paraná presented a more severe epidemiological outcome compared to Rio Grande do Sul.
导言:新型冠状病毒病(COVID-19)是由 SARS-CoV-2 引起的,是一种致死率很高的呼吸道和新陈代谢疾病的病原体,至今仍是一个公共卫生问题。巴西和全世界的社会不平等现象都在加剧。值得注意的是,由于缺乏统一的全民医疗保健系统,导致感染 SARS-CoV-2 和表现为 COVID-19 的人的不平等和生存机会增加。南部地区已成为巴西病例数第二高的地区:评估巴西南部地区南里奥格兰德州和巴拉那州的发病率、致死率和死亡率等流行病学结果:利用南里奥格兰德州和巴拉那州卫生部门公开的 COVID-19 病例和死亡的官方二手数据,开展了一项生态时间序列研究。时间序列的构建采用了 Prais-Winsten 回归模型。统计分析使用 STATA 14.0 软件进行:结果表明,南里奥格兰德州的发病率在 2020 年呈上升趋势,在 2021 年呈下降趋势(p<0.05)。死亡率方面,2020 年上升,2021 年和 2022 年下降(p<0.05)。在评估致死率时,整个期间都呈下降趋势(p<0.05)。就巴拉那州而言,发病率在 2020 年和整个期间都有所上升,而在 2021 年和 2022 年则有所下降(p<0.05)。死亡率在 2020 年保持稳定,在 2021 年和 2022 年有所下降(p<0.05):COVID-19大流行是巴拉那州和南里奥格兰德州的一个严重公共卫生问题。与南里奥格兰德州相比,巴拉那州的流行病学结果更为严重。
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引用次数: 1
Self-perceived stress by women during the COVID-19 pandemic: an online survey with brazilian physiotherapists COVID-19 大流行期间妇女的自我压力感知:对巴西理疗师的在线调查
Q2 Medicine Pub Date : 2024-04-11 DOI: 10.36311/jhgd.v34.15398
P. C. Rocon, Flavia Marini Paro, Rodrigo Daros Vieira, Amanda Cristina de Souza Andrade, Marcela Cangussu Barbalho-Moulim, Christyne Gomes Toledo De Oliveira, José Roberto Gonçalves De Abreu, Halina Duarte
Introduction: the COVID-19 pandemic highlighted the need to investigate the factors related to stress in female health professionals since women and men are exposed differently to pandemic consequences.Objective: to analyze which psychosocial demands, sociodemographic, and clinical factors were associated with high levels of perceived stress among Brazilian female physiotherapists during the COVID-19 pandemic.Methods: this is a cross-sectional study. The data were collected using the Perceived Stress Scale and an online questionnaire sent by e-mail. Unadjusted and adjusted odds ratios (ORs), with their respective 95% CI, were estimated by logistic regression.Results: the sample was compounded by 339 physiotherapists. Participants who reported a lot/extreme concern with household workers (OR = 2.76; 95% CI: 1.40; 5.46), or relationship with a partner (OR = 4.06; 95% CI: 1.79; 9.21) or financial questions (OR = 2.24; 95% CI: 1.15; 4.35) were more likely to report high levels of perceived stress. In conclusion, the psychosocial demands associated with high levels of perceived stress are high or extreme concern with household chores, or with the relationship with a partner, or financial issues.Conclusion: the factors associated with high levels of perceived stress in this sample of Brazilian physiotherapists were the following psychosocial demands: high or extreme concern with household chores, high or extreme with a relationship with a partner, or high or extreme with financial issues.
导言:COVID-19 大流行突显了调查女性卫生专业人员压力相关因素的必要性,因为女性和男性面临的大流行后果不同。目的:分析在 COVID-19 大流行期间,哪些社会心理需求、社会人口学和临床因素与巴西女性物理治疗师的高感知压力相关。方法:这是一项横断面研究,使用感知压力量表和通过电子邮件发送的在线问卷收集数据。结果:样本由 339 名物理治疗师组成。报告对家务工作者(OR = 2.76;95% CI:1.40;5.46)、与伴侣的关系(OR = 4.06;95% CI:1.79;9.21)或财务问题(OR = 2.24;95% CI:1.15;4.35)非常关注/极度关注的参与者更有可能报告高水平的感知压力。结论:在这一巴西物理治疗师样本中,与高水平压力感知相关的因素是以下社会心理需求:高水平或极端关注家务、高水平或极端关注与伴侣的关系、高水平或极端关注财务问题。
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引用次数: 1
What do we know about the perpetrators of sexual homicide of adult victims? A systematic review and qualitative meta-synthesis 我们对性杀害成年受害者的犯罪者了解多少?系统回顾与定性元综合
Q2 Medicine Pub Date : 2024-04-11 DOI: 10.36311/jhgd.v34.15782
Maria Vitória Barros Moreira, Tamires França Visoto, Priscilla Rayanne E. Silva Noll, Jefferson Drezett
Introduction: sexual homicide is defined as lethal violence associated with sexual elements or motivations, predominantly perpetrated by men against women. Despite being a less frequent crime, there is a growing clinical and forensic interest in its specificities and the characteristics of the aggressor.Objective: to review the scientific literature on men who commit sexual homicide against adult victims.Methods: systematic review with MeSH ((“Sex Offenses”[Mesh]) AND “Homicide”[Mesh]) in the databases of MEDLINE, LILACS, MENDELEY and SciELO, between 1992 and 2023. The PICO strategy was used with the studied population (male sexual offenders), intervention (homicide of adult victims), context (sexual violence), and outcome (potential relationship between the issues). The stages of article selection and analysis involved two independent researchers. Original studies were included, excluding reviews, editorials, conference proceedings, books and chapters, theses, and dissertations. The selected articles were presented through qualitative meta-synthesis.Results: of the 70 selected articles, 66 articles (94.2%) adopted quantitative methods, 2 (2.9%) qualitative design, and 2 (2.9%) case reports. We found 41 articles (58.6%) conducted in North America and 22 articles (31.4%) in Europe, totaling 63 articles (90.0%). Another five articles (7.1%) were from Asia, one (1.4%) from Africa, and one (1.4%) from Oceania. In 52 articles (74.3%), there was an emphasis on aspects related to psychiatric, behavioral, or psychological disorders of the perpetrator, sexual sadism, or forms of sexual violence or lethal outcomes employed.Conclusion: sexual homicidal men possess characteristics that set them apart from other homicidal offenders or those who commit sexual violence, directing their crimes towards a heterogeneous group of adult victims. Studies have focused on the psychiatric and behavioral disorders of the perpetrator, as well as the relationship with traumatic experiences in childhood.
导言:性杀人被定义为与性因素或性动机相关的致命暴力,主要由男性对女性实施。尽管这种犯罪不太常见,但临床和法医对其特殊性和施暴者特征的兴趣却与日俱增。研究目的:回顾有关男性对成年受害者实施性杀戮的科学文献。研究方法:1992 年至 2023 年间,在 MEDLINE、LILACS、MENDELEY 和 SciELO 数据库中使用 MeSH("性犯罪"[Mesh])和 "杀人"[Mesh])进行系统回顾。采用的 PICO 策略包括研究人群(男性性犯罪者)、干预措施(成年受害者凶杀案)、背景(性暴力)和结果(问题之间的潜在关系)。文章筛选和分析阶段由两名独立研究人员进行。所选文章均为原创研究,不包括评论、社论、会议论文集、书籍和章节、论文和学位论文。结果:在所选的 70 篇文章中,66 篇(94.2%)采用了定量方法,2 篇(2.9%)采用了定性设计,2 篇(2.9%)采用了病例报告。我们发现 41 篇文章(58.6%)在北美进行,22 篇文章(31.4%)在欧洲进行,共计 63 篇文章(90.0%)。另有 5 篇文章(7.1%)来自亚洲,1 篇(1.4%)来自非洲,1 篇(1.4%)来自大洋洲。在 52 篇文章(74.3%)中,重点强调了与犯罪者的精神、行为或心理障碍、性虐待狂、性暴力形式或所采用的致命结果有关的方面。结论:性杀人犯具有有别于其他杀人罪犯或性暴力罪犯的特征,他们的犯罪对象是一个异质的成年受害者群体。研究的重点是犯罪者的精神和行为障碍,以及与童年创伤经历的关系。
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引用次数: 1
Space-temporal analysis of the incidence, mortality and case fatality of COVID-19 in the State of Rio Grande do Norte, in the period from 2020 to 2022, in the Northeast of Brazil 对 2020 至 2022 年期间巴西东北部北里奥格兰德州 COVID-19 发病率、死亡率和病死率的时空分析
Q2 Medicine Pub Date : 2024-04-11 DOI: 10.36311/jhgd.v34.15777
Paula Christianne Gomes Gouveia Souto Maia, Matheus Paiva Emídio Cavalcanti, Fernando Augusto Marinho dos Santos Figueira, Gabrielle Do Amaral Virgínio Pereira, Woska Pires da Costa, Luiz Carlos de Abreu
Introduction: the COVID-19 pandemic, caused by the SARS-CoV-2 coronavirus, has had a great impact on the state of Rio Grande do Norte, as well as around the world, constituting a relevant challenge for public health. Since its emergence, the disease has spread widely, causing a significant number of confirmed cases and deaths in the state.Objective: to analyze the trend of incidence, mortality and case fatality of COVID-19 in the state of Rio Grande do Norte, located in the Northeast region of Brazil, between 2020 and 2022.Methods: consists of an ecological analysis of time series of retrospective secondary data in population level. Incidence and mortality rates per 100,000 inhabitants were estimated, as well as case fatality and daily percentage variation, both expressed in percentages. The daily percentage variation was calculated using the generalized linear regression technique using the Prais-Winsten method, and served to classify the trend as increasing, decreasing or stationary, considering a significance level of 95%.Results: data analysis showed the registration of 582,618 cases and 8,689 deaths from COVID-19 in the state of Rio Grande do Norte, during the period from March 2020 to December 2022. There was an initial increase in the incidence rate in 2020, followed by a significant reduction in 2021 and 2022. Mortality showed a decreasing trend in 2021 and a stationary trend in 2022, without notable variation in 2020. The case fatality rate decreased in 2020, but did not show significant trends in the following years.Conclusion: the epidemiological analysis of COVID-19 in the state of Rio Grande do Norte revealed variations in incidence, mortality and case fatality over the study period. The daily percentage change over the total period of the incidence time series was stationary, while mortality and case fatality were decreasing.
导言:由 SARS-CoV-2 冠状病毒引起的 COVID-19 大流行对北里约格朗德州乃至全世界都产生了巨大影响,对公共卫生构成了相关挑战。目标:分析 2020 年至 2022 年期间,位于巴西东北部地区的北里奥格兰德州 COVID-19 的发病率、死亡率和病死率的趋势。方法:包括对人口层面的回顾性二级数据时间序列进行生态分析。估算了每 10 万居民的发病率和死亡率,以及病例死亡率和日变化百分比,均以百分比表示。结果:数据分析显示,2020 年 3 月至 2022 年 12 月期间,北里奥格兰德州登记的 COVID-19 病例为 582 618 例,死亡病例为 8 689 例。发病率在 2020 年开始上升,随后在 2021 年和 2022 年显著下降。死亡率在 2021 年呈下降趋势,在 2022 年呈稳定趋势,在 2020 年没有明显变化。结论:对北里奥格兰德州 COVID-19 的流行病学分析表明,在研究期间,发病率、死亡率和病死率均有变化。在整个研究期间,发病率时间序列的每日百分比变化是稳定的,而死亡率和病死率则呈下降趋势。
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引用次数: 1
Temporal evolution of traffic accident mortality rates in the State of São Paulo, Brazil, in the period 2009-2019 2009-2019 年巴西圣保罗州交通事故死亡率的时间演变
Q2 Medicine Pub Date : 2024-04-11 DOI: 10.36311/jhgd.v34.15831
Beatriz Cecilio Bebiano, Luiz Carlos de Abreu, Rafael Carboni de Souza, Cleber Furlan, José Luiz Figueiredo, Woska Pires da Costa, Francisco Naildo Cardoso Leitão, Luciano Miller Reis Rodrigues
Introduction: external causes are considered a public health problem in the world, associated with socioeconomic, political, and cultural diversities. Among them, traffic accidents stand out. Objective: to assess the trend in traffic accident mortality for each sex in the state of São Paulo, Brazil. Methods: ecological study of time series analyses. Secondary data referring to deaths from traffic accidents by place of residence in the state of São Paulo, Brazil, in the period 2009 - 2019 were used. Results: the total mortality rate in 2019 for females is 39.80 and for males, 185.85, with a reduction of 4.96% per year for both sexes. The trends in mortality from traffic accidents for females proved to be stationary for motorcyclists, motorized tricycle, pickup truck, heavy transport vehicle, and bus occupants at the end of the study period. For males, the same pattern was observed, but only for truck, heavy transport vehicle, and bus occupants. In the rest of the vehicles, the mortality rate showed decreasing trends. Conclusion: the highest number of deaths occurred among males (81.38%), aged between 20 and 49 years (58.70%), single (49.12%), on public roads (46.73%) and hospitals (45.64%). Females have more stationary trends than males.
导言:外因被认为是世界上的一个公共卫生问题,与社会经济、政治和文化多样性有关。其中,交通事故尤为突出。目的:评估巴西圣保罗州男女交通事故死亡率的变化趋势。方法:时间序列分析生态研究。使用了巴西圣保罗州 2009 - 2019 年期间按居住地分列的交通事故死亡人数的二手数据。结果:2019 年女性总死亡率为 39.80,男性总死亡率为 185.85,男女总死亡率每年下降 4.96%。事实证明,在研究期结束时,摩托车驾驶员、机动三轮车、皮卡、重型运输车和公交车乘员的女性交通事故死亡率呈静止趋势。对于男性而言,也观察到了同样的模式,但仅限于卡车、重型运输车辆和公共汽车的乘员。其余车辆的死亡率呈下降趋势。结论:死亡人数最多的是男性(81.38%)、20 至 49 岁(58.70%)、单身(49.12%)、公共道路(46.73%)和医院(45.64%)。女性比男性有更多的固定趋势。
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引用次数: 0
Beyond ultra-processed foods: the new direction of the basic food basket in Brazil 超越超加工食品:巴西基本口粮篮的新方向
Q2 Medicine Pub Date : 2024-04-11 DOI: 10.36311/jhgd.v34.15748
M. Cattafesta, Luciane Bresciani Salaroli
Decree 11.936/2024 initiates a significant transformation in the Brazilian basic food basket, focusing on encouraging healthier and more sustainable eating habits. By prioritizing whole foods and restricting ultra-processed foods, it aligns with nutritional policy guidelines and tax reform, demonstrating a commitment to public health and food sustainability. The document reconciles with the recommendations set forth by the Dietary Guidelines for the Brazilian Population, which emphasizes seasonality, family farming, local and regional traditions, biodiversity, and environmental respect essential elements for food and nutritional security that offer direct benefits to public health. Through this approach, it seeks to guide the population towards balanced eating practices, ensuring access to nutritionally adequate and sustainable food, especially for the most vulnerable segments of society.
第 11.936/2024 号法令对巴西的基本食品篮子进行了重大改革,重点是鼓励人们养成更健康、更可持续的饮食习惯。通过优先考虑全食品和限制超加工食品,该法令与营养政策指导方针和税收改革相一致,表明了对公共卫生和食品可持续性的承诺。该文件与《巴西居民膳食指南》提出的建议相一致,后者强调季节性、家庭农业、地方和区域传统、生物多样性和尊重环境是食品和营养安全的基本要素,可直接惠及公众健康。通过这种方法,它力求引导人们养成均衡饮食的习惯,确保人们,特别是社会最弱势群体,能够获得营养充足和可持续的食物。
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引用次数: 0
Mortality from Stroke in Pará, Brazilian Amazon: a Joinpoint Analysis 巴西亚马逊帕拉州的中风死亡率:连接点分析
Q2 Medicine Pub Date : 2024-04-11 DOI: 10.36311/jhgd.v34.15794
Gabriel Roni, Alexandre Castelo Branco Araújo, Helder Maud, Mathias Noll, Hugo Macedo de Souza Jr, Marcelo Ferraz Campos, Orivaldo Florencio de Souza
Introduction: Stroke is a significant cause of death worldwide. Temporal studies show a downward trend in mortality rates in recent decades, with variability between countries. The State of Pará, in northern Brazil, has a low human development index and high mortality from stroke; however, little research is reported.Objective: This study aims to analyze the trend in stroke mortality in the adult population of Pará, between 2000 and 2021.Method: This is an ecological, time series study based on official secondary population data. Joinpoint regression models were used to identify the trend of each coefficient segment of the mortality rate and years of potential life lost.Results: There were 49,259 deaths in this period, with an absolute increase in fatalities during the time series and an increase in the age group. The mortality coefficient showed a stationary mortality trend of 0.4% between 2000 and 2021 (p=0.576); however, after 2008, the trend decreased -1.0% (p=0.003). In the stratified analysis, a decreasing mortality trend was detected: -2.3% between 30 and 39 years old (p<0.001), -2.8% between 40 and 49 years old (p<0.001), -2.1% between 50 and 59 years old (p<0.001) and -1.4% between 60 and 69 years old (p<0.001), between the year 2000 and 2021. In the other age groups, the trend decreased -2.5% between 20 and 29 years old after 2006 (p= 0.003), -1.8% between 70 and 79 years old after 2008 (p=0.001), and -5.1% among 80 years old and over after 2016 (p=0.010).Conclusion: The mortality trend attributed to stroke among adults in Pará State remained stable from 2000 to 2021. Despite this stability, the absolute number of deaths remained consistently high, underscoring the critical need to mitigate risk factors and enhance the care and management of affected individuals.
引言中风是世界范围内的一个重要死因。时间研究表明,近几十年来死亡率呈下降趋势,但各国之间存在差异。位于巴西北部的帕拉州人类发展指数较低,中风死亡率较高,但相关研究报告却很少:本研究旨在分析 2000 年至 2021 年期间帕拉州成人中风死亡率的变化趋势:这是一项基于官方二级人口数据的生态学时间序列研究。采用连接点回归模型来确定死亡率各系数段的趋势和潜在寿命损失年数:在此期间,共有 49 259 人死亡,死亡人数在时间序列中绝对增加,年龄组也有所增加。死亡率系数显示,2000 年至 2021 年期间,死亡率呈 0.4% 的静态趋势(p=0.576);然而,2008 年之后,该趋势下降了 -1.0% (p=0.003)。在分层分析中发现,2000 年至 2021 年期间,死亡率呈下降趋势:30 至 39 岁为-2.3%(p<0.001),40 至 49 岁为-2.8%(p<0.001),50 至 59 岁为-2.1%(p<0.001),60 至 69 岁为-1.4%(p<0.001)。在其他年龄组中,2006 年之后,20 至 29 岁年龄组的死亡率呈下降趋势-2.5%(p= 0.003),2008 年之后,70 至 79 岁年龄组的死亡率呈下降趋势-1.8%(p=0.001),2016 年之后,80 岁及以上年龄组的死亡率呈下降趋势-5.1%(p=0.010):结论:2000 年至 2021 年期间,帕拉州成人中风死亡率趋势保持稳定。结论:2000 年至 2021 年期间,帕拉州成人中风死亡率趋势保持稳定,但死亡人数的绝对值仍然居高不下,这说明亟需减少风险因素,加强对患者的护理和管理。
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引用次数: 1
Mortality from cerebral stroke in the State of Pernambuco, Brazil: an ecological study 巴西伯南布哥州脑卒中死亡率:生态研究
Q2 Medicine Pub Date : 2024-04-11 DOI: 10.36311/jhgd.v34.15781
Ana Carolina Netto Djaló, Orivaldo Florencio de Souza, Helder Maud, Matheus Paiva Emídio Cavalcanti, Gabrielle do Amaral Virginio Pereira, Marcelo Ferraz Campos, José Luiz Figueiredo
Introduction: cerebrovascular accident (CVA) is the second leading cause of death globally, characterized by cerebrovascular events due to dysfunctions in the cerebral blood supply. It can be ischemic or hemorrhagic and has high morbidity and mortality rates. In Brazil, it is the main cause of death, disabling many over 50 years of age and leading to around 40% of early retirements. Despite advances in initial treatment, mortality rates remain high, indicating flaws in prevention and treatment strategies. Therefore, the World Health Organization (WHO) emphasizes the need for immediate implementation of preventive and treatment measures for this condition.Objective: to evaluate the trend in the mortality coefficient and proportional mortality from stroke in the population of Pernambuco, from 2000 to 2021.Methods: This is an ecological time series study with data from the population of the state of Pernambuco, located in northeast region of Brazil, from 2000 to 2021. The eligibility criteria were deaths with a stroke occurring in the state of Pernambuco. Information on mortality, population estimates and number of deaths by sex and age group were extracted from the database of the Department of Informatics of the Unified Health System (DATASUS). For statistical analysis, it was calculated the mortality coefficient, proportional mortality, mean, standard deviation, skewness and kurtosis. The temporal trend of stroke was assessed by jointpoint regression.Results: Between 2000 and 2021, there were 39,410 deaths from stroke. Around 49.0% were male and 51.0% female. The female sex had an average of 913.45 in the number of deaths, being quantitatively higher than the average identified for the male sex of 877.04 deaths. The years with the highest number of deaths were 2006, 2007 and 2008, while 2018 had the lowest number. There was a progressive increase in the number of deaths from stroke from 2018 to 2021. There was a decline in the average annual percentage variation in the mortality rate for stroke in all groups studied, in addition to a drop in the average annual percentage of proportional mortality for stroke in the entire population. Throughout the period, there was a decline in the average annual percentage of proportional mortality from stroke in the entire population studied.Conclusion: In the period from 2000 to 2021 there was a greater number of deaths due to stroke in women in contrast to men in the population of Pernambuco, Brazil. Furthermore, there was a downward trend in stroke rates in both the mortality rate and proportional mortality. In the period from 2018 to 2021 there was a progressive increase in the mortality rate and proportional mortality from stroke.
导言:脑血管意外(CVA)是全球第二大死亡原因,其特点是由于脑供血功能障碍导致的脑血管事件。它可以是缺血性的,也可以是出血性的,发病率和死亡率都很高。在巴西,它是导致死亡的主要原因,使许多 50 岁以上的人致残,并导致约 40% 的人提前退休。尽管初期治疗取得了进展,但死亡率仍然很高,这表明预防和治疗策略存在缺陷。因此,世界卫生组织(WHO)强调有必要立即实施针对这种疾病的预防和治疗措施。目标:评估 2000 年至 2021 年伯南布哥州人口中风死亡率系数和死亡率比例的变化趋势:这是一项生态时间序列研究,数据来自 2000 年至 2021 年巴西东北部地区伯南布哥州的人口。研究对象为伯南布哥州的中风死亡者。从统一卫生系统信息部(DATASUS)的数据库中提取了按性别和年龄组划分的死亡率、人口估计数和死亡人数等信息。为进行统计分析,计算了死亡率系数、死亡率比例、平均值、标准差、偏度和峰度。通过联合点回归评估了中风的时间趋势:结果:2000 年至 2021 年期间,共有 39 410 人死于中风。约 49.0% 为男性,51.0% 为女性。女性的平均死亡人数为 913.45 人,在数量上高于男性的平均死亡人数 877.04 人。死亡人数最多的年份是 2006 年、2007 年和 2008 年,死亡人数最少的年份是 2018 年。从 2018 年到 2021 年,死于中风的人数逐渐增加。在研究的所有组别中,中风死亡率的年均百分比变化均有所下降,此外,整个人口中中风死亡率的年均百分比比例也有所下降。在整个研究期间,中风死亡率在所有研究人群中的年均比例有所下降:结论:2000 年至 2021 年期间,在巴西伯南布哥州的人口中,女性死于中风的人数多于男性。此外,中风死亡率和死亡率比例均呈下降趋势。在 2018 年至 2021 年期间,中风死亡率和死亡率比例逐渐上升。
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引用次数: 1
Evaluation of whole blood profile as a tool in COVID-19 diagnosis and screening. A cross-sectional study 评估作为 COVID-19 诊断和筛查工具的全血图谱。横断面研究
Q2 Medicine Pub Date : 2024-04-11 DOI: 10.36311/jhgd.v34.15750
Nicolle Godoy Moreira, Thaciane Alkmim Bibo, Ana Carolina Macedo Gaiatto, Joyce R. Santos Raimundo, Jéssica Freitas Araújo Encinas, Beatriz da C. Aguiar Alves, Thaís Moura Gascón, F. L. Affonso Fonseca, Glaucia Luciano da Veiga
Backgroung: the COVID-19 epidemic began in December 2019, and the shortage of diagnostic resources has affected the reported data on the number of cases, resulting in variations in reported cases between countries. This situation underscores the necessity for a deeper understanding of SARS-CoV-2 pathophysiology, including blood profiles and potential predictors.Methods: hematological variables were studied in 200 patients diagnosed with COVID-19, before the vaccination period started. We analyzed hemogram parameters: erythrocytes, hemoglobin, mean corpuscular hemoglobin (MCH), mean corpuscular volume (MCV) mean corpuscular hemoglobin concentration (MCHC), hematocrit, red cell distribution width (RDW), platelets, mean platelet volume (MPV), leukocytes, neutrophils, lymphocytes, neutrophils/lymphocytes ratio and Platelet-to-Lymphocyte Ratio (PLR), up to 9 days after positive result for COVID-19.Results: the positive COVID-19 group presented a higher mean age, as well as a higher frequency of male individuals. Erythrocyte, hemoglobin, hematocrit and MCH values were significantly lower, while RDW and PLR showed higher values in the positive group. Leukocytes, neutrophil and the neutrophil/lymphocyte ratio presented higher values in the positive COVID-19 group.Conclusion: data showed that the hemogram, a low-cost, minimally invasive exam, supports diagnosis and screening of COVID-19, allowing better evaluation of the disease course and assisting medical decisions facing lack of resources in a pandemic situation.
背景:COVID-19疫情始于2019年12月,诊断资源的短缺影响了病例数的报告数据,导致各国报告的病例数存在差异。这种情况凸显了深入了解 SARS-CoV-2 病理生理学的必要性,包括血液特征和潜在的预测因素。方法:在疫苗接种期开始之前,我们对 200 名确诊为 COVID-19 的患者进行了血液学变量研究。我们分析了血液图参数:红细胞、血红蛋白、平均体细胞血红蛋白 (MCH)、平均体细胞容积 (MCV)、平均体细胞血红蛋白浓度 (MCHC)、血细胞比容、红细胞分布宽度 (RDW)、在 COVID-19 检测结果呈阳性后 9 天内,还需检测血小板、平均血小板体积 (MPV)、白细胞、中性粒细胞、淋巴细胞、中性粒细胞/淋巴细胞比值和血小板淋巴细胞比值 (PLR)。结果:COVID-19 阳性组的平均年龄较大,男性比例较高。阳性组的红细胞、血红蛋白、血细胞比容和 MCH 值明显较低,而 RDW 和 PLR 值较高。白细胞、中性粒细胞和中性粒细胞/淋巴细胞比值在 COVID-19 阳性组中显示较高值。结论:数据显示,血液图谱是一种低成本、微创的检查方法,可支持 COVID-19 的诊断和筛查,从而更好地评估病程,并在大流行病缺乏资源的情况下协助医疗决策。
{"title":"Evaluation of whole blood profile as a tool in COVID-19 diagnosis and screening. A cross-sectional study","authors":"Nicolle Godoy Moreira, Thaciane Alkmim Bibo, Ana Carolina Macedo Gaiatto, Joyce R. Santos Raimundo, Jéssica Freitas Araújo Encinas, Beatriz da C. Aguiar Alves, Thaís Moura Gascón, F. L. Affonso Fonseca, Glaucia Luciano da Veiga","doi":"10.36311/jhgd.v34.15750","DOIUrl":"https://doi.org/10.36311/jhgd.v34.15750","url":null,"abstract":"Backgroung: the COVID-19 epidemic began in December 2019, and the shortage of diagnostic resources has affected the reported data on the number of cases, resulting in variations in reported cases between countries. This situation underscores the necessity for a deeper understanding of SARS-CoV-2 pathophysiology, including blood profiles and potential predictors.\u0000Methods: hematological variables were studied in 200 patients diagnosed with COVID-19, before the vaccination period started. We analyzed hemogram parameters: erythrocytes, hemoglobin, mean corpuscular hemoglobin (MCH), mean corpuscular volume (MCV) mean corpuscular hemoglobin concentration (MCHC), hematocrit, red cell distribution width (RDW), platelets, mean platelet volume (MPV), leukocytes, neutrophils, lymphocytes, neutrophils/lymphocytes ratio and Platelet-to-Lymphocyte Ratio (PLR), up to 9 days after positive result for COVID-19.\u0000Results: the positive COVID-19 group presented a higher mean age, as well as a higher frequency of male individuals. Erythrocyte, hemoglobin, hematocrit and MCH values were significantly lower, while RDW and PLR showed higher values in the positive group. Leukocytes, neutrophil and the neutrophil/lymphocyte ratio presented higher values in the positive COVID-19 group.\u0000Conclusion: data showed that the hemogram, a low-cost, minimally invasive exam, supports diagnosis and screening of COVID-19, allowing better evaluation of the disease course and assisting medical decisions facing lack of resources in a pandemic situation.","PeriodicalId":35218,"journal":{"name":"Journal of Human Growth and Development","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140716144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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Journal of Human Growth and Development
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