Pub Date : 2022-01-01DOI: 10.5505/turkhijyen.2022.90532
Yalçın Di̇cle, H. Yazgi, M. Coskun, Zeynal Topalcengiz
{"title":"Synergistic Antibacterial Effect of Ciprofloxacin and Green Tea Extract on Methicillin-Resistant Staphylococcus aureus (MRSA) Strains Isolated from Clinical Cases","authors":"Yalçın Di̇cle, H. Yazgi, M. Coskun, Zeynal Topalcengiz","doi":"10.5505/turkhijyen.2022.90532","DOIUrl":"https://doi.org/10.5505/turkhijyen.2022.90532","url":null,"abstract":"","PeriodicalId":35553,"journal":{"name":"Turk hijiyen ve deneysel biyoloji dergisi. Turkish bulletin of hygiene and experimental biology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70678122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.5505/turkhijyen.2022.06887
H. Mirahmadi, F. Gorgani, M. Metanat, S. Etemadi, Seyed Mehdi Tabaatabaei̇, Mohammad Kazem Momeni
{"title":"Nested-PCR Assay for molecular identification of cutaneous leishmaniasis species using kinetoplast DNA gene in Mirjaveh and Reg-e Malek provinces (IRAN)","authors":"H. Mirahmadi, F. Gorgani, M. Metanat, S. Etemadi, Seyed Mehdi Tabaatabaei̇, Mohammad Kazem Momeni","doi":"10.5505/turkhijyen.2022.06887","DOIUrl":"https://doi.org/10.5505/turkhijyen.2022.06887","url":null,"abstract":"","PeriodicalId":35553,"journal":{"name":"Turk hijiyen ve deneysel biyoloji dergisi. Turkish bulletin of hygiene and experimental biology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70675606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.5505/turkhijyen.2022.26937
Tuğçe Şimşek Bozok, Taylan Bozok
{"title":"Distribution and antibiotic susceptibility of microorganisms isolated from blood cultures of patients hospitalized in intensive care units: a two-year evaluation","authors":"Tuğçe Şimşek Bozok, Taylan Bozok","doi":"10.5505/turkhijyen.2022.26937","DOIUrl":"https://doi.org/10.5505/turkhijyen.2022.26937","url":null,"abstract":"","PeriodicalId":35553,"journal":{"name":"Turk hijiyen ve deneysel biyoloji dergisi. Turkish bulletin of hygiene and experimental biology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70675969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.5505/turkhijyen.2022.69009
V. Raissi, Zahra BABAEİ SAMANİ, Mohammadreza Bagherpoor, Z. Sohrabi, S. Etemadi, O. Raiesi, Pantea Jalali, M. Zareie, Gita Alizadeh, Zeynab HASHEMİ BAGHİ, Asmaa Nasr
Objective: Toxoplasma gondii , Toxocara spp, and antinuclear antibodies (ANAs) have been reported as a cause of abortion. To determine the prevalence rate of T. gondii, Toxocara spp, and ANAs in aborted women, and to investigate the association between infection and the number of the sociodemographic estimated risk factors. Methods: This study was carried out in aborted women referred to the Qaem hospital in Mashhad city (Razavi Khorasan Province). Serum samples were examined for the presence of Antinuclear Antibody (IgG antibodies), anti- Toxoplasma gondii IgG and IgM antibodies, and IgG anti-toxocariasis spp antibodies by ELISA (Enzyme-Linked Immunosorbent Assay) kit. Data like contact with animals’ cats and dogs, age, and Type of cause of abortion (in most cases) were collected as risk factors for the prevalence of infection. T. gondii and Toxocara spp detected in 9%, also ANAs detected in cases with T. gondii in 24% and 10% with Toxocara spp. ANAs showed positivity with co-infection of T. gondii and Toxocara spp in 8%. This study showed a significant association between infection of each T. gondii , Toxocara spp, and ANAs with age and animal contact such as cats and dogs. Conclusion: These study findings indicated that there is a relatively high prevalence of T. gondii , Toxocara spp, and ANAs in pregnant women with abortion. The coexistence of two agents or of one with ANAs increases the risk of abortion. All of them showed association with age and contact with domestic animals like cats
{"title":"Evaluation of Antinuclear antibodies in pregnant women with abortion with toxocariasis and toxoplasmosis in Iran","authors":"V. Raissi, Zahra BABAEİ SAMANİ, Mohammadreza Bagherpoor, Z. Sohrabi, S. Etemadi, O. Raiesi, Pantea Jalali, M. Zareie, Gita Alizadeh, Zeynab HASHEMİ BAGHİ, Asmaa Nasr","doi":"10.5505/turkhijyen.2022.69009","DOIUrl":"https://doi.org/10.5505/turkhijyen.2022.69009","url":null,"abstract":"Objective: Toxoplasma gondii , Toxocara spp, and antinuclear antibodies (ANAs) have been reported as a cause of abortion. To determine the prevalence rate of T. gondii, Toxocara spp, and ANAs in aborted women, and to investigate the association between infection and the number of the sociodemographic estimated risk factors. Methods: This study was carried out in aborted women referred to the Qaem hospital in Mashhad city (Razavi Khorasan Province). Serum samples were examined for the presence of Antinuclear Antibody (IgG antibodies), anti- Toxoplasma gondii IgG and IgM antibodies, and IgG anti-toxocariasis spp antibodies by ELISA (Enzyme-Linked Immunosorbent Assay) kit. Data like contact with animals’ cats and dogs, age, and Type of cause of abortion (in most cases) were collected as risk factors for the prevalence of infection. T. gondii and Toxocara spp detected in 9%, also ANAs detected in cases with T. gondii in 24% and 10% with Toxocara spp. ANAs showed positivity with co-infection of T. gondii and Toxocara spp in 8%. This study showed a significant association between infection of each T. gondii , Toxocara spp, and ANAs with age and animal contact such as cats and dogs. Conclusion: These study findings indicated that there is a relatively high prevalence of T. gondii , Toxocara spp, and ANAs in pregnant women with abortion. The coexistence of two agents or of one with ANAs increases the risk of abortion. All of them showed association with age and contact with domestic animals like cats","PeriodicalId":35553,"journal":{"name":"Turk hijiyen ve deneysel biyoloji dergisi. Turkish bulletin of hygiene and experimental biology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70677119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.5505/turkhijyen.2022.19971
M. Ayhan, A. Kaya Kalem, I. Hasanoğlu, B. Kayaaslan, Rahmet Güner
Objective: Urinary tract infections are the second most common disease in elderly patients and the most common disease related to bacteria. Due to the immune senescence, comorbid diseases and various physiological changes, susceptibility to such infections may develop with age. It is important to know the common pathogens and resistance profile in this patient population for empirical treatment selection. We aimed to evaluate patient characteristics, causative microorganisms and their resistance in elderly patients hospitalized in our clinic due to urinary tract infection. Methods: Patients who were older than 65 years and hospitalized in Ankara City Hospital Infectious Diseases and Clinical Microbiology clinic with a diagnosis of urinary tract infection between March 2019 and March 2020 were retrospectively evaluated. Hospitalization information, patient files and all medical records on the hospital information processing system in terms of demographic characteristics, culture results and resistance status of the pathogens were screened. YOLU ENFEKSİYONLARI Results: A total of 118 patients were included in the study and the mean age of the patients was 74.65 ± 7.4. hypertension (41.5%), diabetes (30.0%) and dementia (18.6%) were the most common comorbid diseases. Urinary procedure history (11.0%) was the most common complicating factor in the patients. Majority (86.0%) of the causative agents were Gram-negative bacteria. Escherichia coli ( E. coli ) (59.0%) and Klebsiella pneumoniae ( K. pneumoniae ) (17.0%) were the most commonly isolated pathogens, respectively. While extended spectrum beta-lactamase (ESBL) was observed as 56.0% in E. coli and 40.0% in K. pneumoniae , carbapenem resistance was observed at a rate of 20.0% in K. pneumoniae strains. Patients with and without mortality were compared in terms of the presence of resistance (ESBL / carbapenem resistance) and distribution of the infectious agents, and there was no statistically significant difference between the two groups (p=0.573 and p=0.161, respectively). Conclusion: Urinary tract infections are the most common cause of bacteremia in the elderly population and often require hospitalization. Aging is one of the major risk factors for the development of urinary tract infections due to reasons such as urinary incontinence, urinary retention, hospitalizations requiring urinary catheterization, staying in a nursing home and immune aging. It can cause significant morbidity and mortality. In our study, resistance rates were high in the isolated specimens. This should be take into consideration during choosing empiric treatment. Each center should periodically monitor infectious agents and their resistance profiles which observed in their specific patient populations and should develop their own solution strategies to reduce antimicrobial resistance and provide effective treatment to
{"title":"Evaluation of urinary tract infections and causative agents in geriatric patients","authors":"M. Ayhan, A. Kaya Kalem, I. Hasanoğlu, B. Kayaaslan, Rahmet Güner","doi":"10.5505/turkhijyen.2022.19971","DOIUrl":"https://doi.org/10.5505/turkhijyen.2022.19971","url":null,"abstract":"Objective: Urinary tract infections are the second most common disease in elderly patients and the most common disease related to bacteria. Due to the immune senescence, comorbid diseases and various physiological changes, susceptibility to such infections may develop with age. It is important to know the common pathogens and resistance profile in this patient population for empirical treatment selection. We aimed to evaluate patient characteristics, causative microorganisms and their resistance in elderly patients hospitalized in our clinic due to urinary tract infection. Methods: Patients who were older than 65 years and hospitalized in Ankara City Hospital Infectious Diseases and Clinical Microbiology clinic with a diagnosis of urinary tract infection between March 2019 and March 2020 were retrospectively evaluated. Hospitalization information, patient files and all medical records on the hospital information processing system in terms of demographic characteristics, culture results and resistance status of the pathogens were screened. YOLU ENFEKSİYONLARI Results: A total of 118 patients were included in the study and the mean age of the patients was 74.65 ± 7.4. hypertension (41.5%), diabetes (30.0%) and dementia (18.6%) were the most common comorbid diseases. Urinary procedure history (11.0%) was the most common complicating factor in the patients. Majority (86.0%) of the causative agents were Gram-negative bacteria. Escherichia coli ( E. coli ) (59.0%) and Klebsiella pneumoniae ( K. pneumoniae ) (17.0%) were the most commonly isolated pathogens, respectively. While extended spectrum beta-lactamase (ESBL) was observed as 56.0% in E. coli and 40.0% in K. pneumoniae , carbapenem resistance was observed at a rate of 20.0% in K. pneumoniae strains. Patients with and without mortality were compared in terms of the presence of resistance (ESBL / carbapenem resistance) and distribution of the infectious agents, and there was no statistically significant difference between the two groups (p=0.573 and p=0.161, respectively). Conclusion: Urinary tract infections are the most common cause of bacteremia in the elderly population and often require hospitalization. Aging is one of the major risk factors for the development of urinary tract infections due to reasons such as urinary incontinence, urinary retention, hospitalizations requiring urinary catheterization, staying in a nursing home and immune aging. It can cause significant morbidity and mortality. In our study, resistance rates were high in the isolated specimens. This should be take into consideration during choosing empiric treatment. Each center should periodically monitor infectious agents and their resistance profiles which observed in their specific patient populations and should develop their own solution strategies to reduce antimicrobial resistance and provide effective treatment to","PeriodicalId":35553,"journal":{"name":"Turk hijiyen ve deneysel biyoloji dergisi. Turkish bulletin of hygiene and experimental biology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70676076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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