Pub Date : 2022-01-01DOI: 10.5505/turkhijyen.2022.62444
Ayse Sakioglu, Sibel Eldemir, İ. Y. Avcı
As a result of the work initiated by the World Health Organization with the slogan “Safe blood begins with me”, the understanding of quality in blood banking and transfusion medicine has begun to be felt more clearly. In our country, quality studies in transfusion medicine gained momentum with the “Safe blood supply project”. For blood service units, quality has gone beyond the understanding of “write what you do, do what you write” and become a part of the safe blood supply process. The fact that the understanding of the quality management system made its presence felt more intensely created the need for blood service units to express the positive contributions of the quality management system with concrete indicators. Monitoring the processes in transfusion medicine with the quality indicators to be established can be the targeted concrete evidence. Quality indicators are also important for evaluating and comparing the performances of blood service units. There are various studies on establishing quality indicators in transfusion medicine at national and international level. However, quality indicators for transfusion centers were barely mentioned in these studies. There are no standardized quality indicators for transfusion centers at the national level. In our article, ise transfüzyon tıbbı we evaluated the deficiencies in quality indicators in blood banking and transfusion medicine in Turkey. We have developed exemplary quality indicators by making use of international and national studies. We believe that in the future, more comprehensive studies will be carried out and standardized blood banking and transfusion medicine quality indicators approved by the competent authority will
由于世界卫生组织以“安全血液从我做起”为口号开展的工作，人们开始更加清楚地认识到血库和输血医学的质量。在我国，随着“安全供血工程”的实施，输血医学质量研究方兴未。对于血液服务单位来说，质量已经超越了“写什么写什么”的理解，成为安全供血过程的一部分。对质量管理体系的理解使其存在感更加强烈，这一事实使得血液服务单位需要用具体的指标来表达质量管理体系的积极贡献。通过建立质量指标对输血医学过程进行监测，可以作为有针对性的具体证据。质量指标对于评价和比较血液服务单位的表现也很重要。国内外对输血医学质量指标的建立进行了各种研究。然而，输血中心的质量指标在这些研究中几乎没有被提及。国家一级的输血中心没有标准化的质量指标。在我们的文章中，ise transfer zyon tıbbı我们评估了土耳其血库和输血医学质量指标的不足。我们利用国际和国家研究，制定了示范性的质量指标。我们相信，未来将开展更全面的研究，并通过主管部门批准的标准化血库和输血医学质量指标
{"title":"Development of quality indicators in the field of blood banking and transfusion medicine in Turkey","authors":"Ayse Sakioglu, Sibel Eldemir, İ. Y. Avcı","doi":"10.5505/turkhijyen.2022.62444","DOIUrl":"https://doi.org/10.5505/turkhijyen.2022.62444","url":null,"abstract":"As a result of the work initiated by the World Health Organization with the slogan “Safe blood begins with me”, the understanding of quality in blood banking and transfusion medicine has begun to be felt more clearly. In our country, quality studies in transfusion medicine gained momentum with the “Safe blood supply project”. For blood service units, quality has gone beyond the understanding of “write what you do, do what you write” and become a part of the safe blood supply process. The fact that the understanding of the quality management system made its presence felt more intensely created the need for blood service units to express the positive contributions of the quality management system with concrete indicators. Monitoring the processes in transfusion medicine with the quality indicators to be established can be the targeted concrete evidence. Quality indicators are also important for evaluating and comparing the performances of blood service units. There are various studies on establishing quality indicators in transfusion medicine at national and international level. However, quality indicators for transfusion centers were barely mentioned in these studies. There are no standardized quality indicators for transfusion centers at the national level. In our article, ise transfüzyon tıbbı we evaluated the deficiencies in quality indicators in blood banking and transfusion medicine in Turkey. We have developed exemplary quality indicators by making use of international and national studies. We believe that in the future, more comprehensive studies will be carried out and standardized blood banking and transfusion medicine quality indicators approved by the competent authority will","PeriodicalId":35553,"journal":{"name":"Turk hijiyen ve deneysel biyoloji dergisi. Turkish bulletin of hygiene and experimental biology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70676719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.5505/turkhijyen.2022.69009
V. Raissi, Zahra BABAEİ SAMANİ, Mohammadreza Bagherpoor, Z. Sohrabi, S. Etemadi, O. Raiesi, Pantea Jalali, M. Zareie, Gita Alizadeh, Zeynab HASHEMİ BAGHİ, Asmaa Nasr
Objective: Toxoplasma gondii , Toxocara spp, and antinuclear antibodies (ANAs) have been reported as a cause of abortion. To determine the prevalence rate of T. gondii, Toxocara spp, and ANAs in aborted women, and to investigate the association between infection and the number of the sociodemographic estimated risk factors. Methods: This study was carried out in aborted women referred to the Qaem hospital in Mashhad city (Razavi Khorasan Province). Serum samples were examined for the presence of Antinuclear Antibody (IgG antibodies), anti- Toxoplasma gondii IgG and IgM antibodies, and IgG anti-toxocariasis spp antibodies by ELISA (Enzyme-Linked Immunosorbent Assay) kit. Data like contact with animals’ cats and dogs, age, and Type of cause of abortion (in most cases) were collected as risk factors for the prevalence of infection. T. gondii and Toxocara spp detected in 9%, also ANAs detected in cases with T. gondii in 24% and 10% with Toxocara spp. ANAs showed positivity with co-infection of T. gondii and Toxocara spp in 8%. This study showed a significant association between infection of each T. gondii , Toxocara spp, and ANAs with age and animal contact such as cats and dogs. Conclusion: These study findings indicated that there is a relatively high prevalence of T. gondii , Toxocara spp, and ANAs in pregnant women with abortion. The coexistence of two agents or of one with ANAs increases the risk of abortion. All of them showed association with age and contact with domestic animals like cats
{"title":"Evaluation of Antinuclear antibodies in pregnant women with abortion with toxocariasis and toxoplasmosis in Iran","authors":"V. Raissi, Zahra BABAEİ SAMANİ, Mohammadreza Bagherpoor, Z. Sohrabi, S. Etemadi, O. Raiesi, Pantea Jalali, M. Zareie, Gita Alizadeh, Zeynab HASHEMİ BAGHİ, Asmaa Nasr","doi":"10.5505/turkhijyen.2022.69009","DOIUrl":"https://doi.org/10.5505/turkhijyen.2022.69009","url":null,"abstract":"Objective: Toxoplasma gondii , Toxocara spp, and antinuclear antibodies (ANAs) have been reported as a cause of abortion. To determine the prevalence rate of T. gondii, Toxocara spp, and ANAs in aborted women, and to investigate the association between infection and the number of the sociodemographic estimated risk factors. Methods: This study was carried out in aborted women referred to the Qaem hospital in Mashhad city (Razavi Khorasan Province). Serum samples were examined for the presence of Antinuclear Antibody (IgG antibodies), anti- Toxoplasma gondii IgG and IgM antibodies, and IgG anti-toxocariasis spp antibodies by ELISA (Enzyme-Linked Immunosorbent Assay) kit. Data like contact with animals’ cats and dogs, age, and Type of cause of abortion (in most cases) were collected as risk factors for the prevalence of infection. T. gondii and Toxocara spp detected in 9%, also ANAs detected in cases with T. gondii in 24% and 10% with Toxocara spp. ANAs showed positivity with co-infection of T. gondii and Toxocara spp in 8%. This study showed a significant association between infection of each T. gondii , Toxocara spp, and ANAs with age and animal contact such as cats and dogs. Conclusion: These study findings indicated that there is a relatively high prevalence of T. gondii , Toxocara spp, and ANAs in pregnant women with abortion. The coexistence of two agents or of one with ANAs increases the risk of abortion. All of them showed association with age and contact with domestic animals like cats","PeriodicalId":35553,"journal":{"name":"Turk hijiyen ve deneysel biyoloji dergisi. Turkish bulletin of hygiene and experimental biology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70677119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.5505/turkhijyen.2022.78200
A. Okan, E. Kaymak, Arda Kaan Üner, S. Silici, Z. Doğanyiğit
{"title":"Apilarnil protects the LPS induced endotoxemic heart","authors":"A. Okan, E. Kaymak, Arda Kaan Üner, S. Silici, Z. Doğanyiğit","doi":"10.5505/turkhijyen.2022.78200","DOIUrl":"https://doi.org/10.5505/turkhijyen.2022.78200","url":null,"abstract":"","PeriodicalId":35553,"journal":{"name":"Turk hijiyen ve deneysel biyoloji dergisi. Turkish bulletin of hygiene and experimental biology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70677337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.5505/turkhijyen.2022.90532
Yalçın Di̇cle, H. Yazgi, M. Coskun, Zeynal Topalcengiz
{"title":"Synergistic Antibacterial Effect of Ciprofloxacin and Green Tea Extract on Methicillin-Resistant Staphylococcus aureus (MRSA) Strains Isolated from Clinical Cases","authors":"Yalçın Di̇cle, H. Yazgi, M. Coskun, Zeynal Topalcengiz","doi":"10.5505/turkhijyen.2022.90532","DOIUrl":"https://doi.org/10.5505/turkhijyen.2022.90532","url":null,"abstract":"","PeriodicalId":35553,"journal":{"name":"Turk hijiyen ve deneysel biyoloji dergisi. Turkish bulletin of hygiene and experimental biology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70678122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.5505/turkhijyen.2022.19971
M. Ayhan, A. Kaya Kalem, I. Hasanoğlu, B. Kayaaslan, Rahmet Güner
Objective: Urinary tract infections are the second most common disease in elderly patients and the most common disease related to bacteria. Due to the immune senescence, comorbid diseases and various physiological changes, susceptibility to such infections may develop with age. It is important to know the common pathogens and resistance profile in this patient population for empirical treatment selection. We aimed to evaluate patient characteristics, causative microorganisms and their resistance in elderly patients hospitalized in our clinic due to urinary tract infection. Methods: Patients who were older than 65 years and hospitalized in Ankara City Hospital Infectious Diseases and Clinical Microbiology clinic with a diagnosis of urinary tract infection between March 2019 and March 2020 were retrospectively evaluated. Hospitalization information, patient files and all medical records on the hospital information processing system in terms of demographic characteristics, culture results and resistance status of the pathogens were screened. YOLU ENFEKSİYONLARI Results: A total of 118 patients were included in the study and the mean age of the patients was 74.65 ± 7.4. hypertension (41.5%), diabetes (30.0%) and dementia (18.6%) were the most common comorbid diseases. Urinary procedure history (11.0%) was the most common complicating factor in the patients. Majority (86.0%) of the causative agents were Gram-negative bacteria. Escherichia coli ( E. coli ) (59.0%) and Klebsiella pneumoniae ( K. pneumoniae ) (17.0%) were the most commonly isolated pathogens, respectively. While extended spectrum beta-lactamase (ESBL) was observed as 56.0% in E. coli and 40.0% in K. pneumoniae , carbapenem resistance was observed at a rate of 20.0% in K. pneumoniae strains. Patients with and without mortality were compared in terms of the presence of resistance (ESBL / carbapenem resistance) and distribution of the infectious agents, and there was no statistically significant difference between the two groups (p=0.573 and p=0.161, respectively). Conclusion: Urinary tract infections are the most common cause of bacteremia in the elderly population and often require hospitalization. Aging is one of the major risk factors for the development of urinary tract infections due to reasons such as urinary incontinence, urinary retention, hospitalizations requiring urinary catheterization, staying in a nursing home and immune aging. It can cause significant morbidity and mortality. In our study, resistance rates were high in the isolated specimens. This should be take into consideration during choosing empiric treatment. Each center should periodically monitor infectious agents and their resistance profiles which observed in their specific patient populations and should develop their own solution strategies to reduce antimicrobial resistance and provide effective treatment to
{"title":"Evaluation of urinary tract infections and causative agents in geriatric patients","authors":"M. Ayhan, A. Kaya Kalem, I. Hasanoğlu, B. Kayaaslan, Rahmet Güner","doi":"10.5505/turkhijyen.2022.19971","DOIUrl":"https://doi.org/10.5505/turkhijyen.2022.19971","url":null,"abstract":"Objective: Urinary tract infections are the second most common disease in elderly patients and the most common disease related to bacteria. Due to the immune senescence, comorbid diseases and various physiological changes, susceptibility to such infections may develop with age. It is important to know the common pathogens and resistance profile in this patient population for empirical treatment selection. We aimed to evaluate patient characteristics, causative microorganisms and their resistance in elderly patients hospitalized in our clinic due to urinary tract infection. Methods: Patients who were older than 65 years and hospitalized in Ankara City Hospital Infectious Diseases and Clinical Microbiology clinic with a diagnosis of urinary tract infection between March 2019 and March 2020 were retrospectively evaluated. Hospitalization information, patient files and all medical records on the hospital information processing system in terms of demographic characteristics, culture results and resistance status of the pathogens were screened. YOLU ENFEKSİYONLARI Results: A total of 118 patients were included in the study and the mean age of the patients was 74.65 ± 7.4. hypertension (41.5%), diabetes (30.0%) and dementia (18.6%) were the most common comorbid diseases. Urinary procedure history (11.0%) was the most common complicating factor in the patients. Majority (86.0%) of the causative agents were Gram-negative bacteria. Escherichia coli ( E. coli ) (59.0%) and Klebsiella pneumoniae ( K. pneumoniae ) (17.0%) were the most commonly isolated pathogens, respectively. While extended spectrum beta-lactamase (ESBL) was observed as 56.0% in E. coli and 40.0% in K. pneumoniae , carbapenem resistance was observed at a rate of 20.0% in K. pneumoniae strains. Patients with and without mortality were compared in terms of the presence of resistance (ESBL / carbapenem resistance) and distribution of the infectious agents, and there was no statistically significant difference between the two groups (p=0.573 and p=0.161, respectively). Conclusion: Urinary tract infections are the most common cause of bacteremia in the elderly population and often require hospitalization. Aging is one of the major risk factors for the development of urinary tract infections due to reasons such as urinary incontinence, urinary retention, hospitalizations requiring urinary catheterization, staying in a nursing home and immune aging. It can cause significant morbidity and mortality. In our study, resistance rates were high in the isolated specimens. This should be take into consideration during choosing empiric treatment. Each center should periodically monitor infectious agents and their resistance profiles which observed in their specific patient populations and should develop their own solution strategies to reduce antimicrobial resistance and provide effective treatment to","PeriodicalId":35553,"journal":{"name":"Turk hijiyen ve deneysel biyoloji dergisi. Turkish bulletin of hygiene and experimental biology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70676076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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