Turk hijiyen ve deneysel biyoloji dergisi. Turkish bulletin of hygiene and experimental biology最新文献

{"title":"The Effects of tDCS on Depression and Anxiety Disorders Induced by Sub-Chronic Stress","authors":"G. Akcay, N. Derin","doi":"10.5505/turkhijyen.2022.06641","DOIUrl":"https://doi.org/10.5505/turkhijyen.2022.06641","url":null,"abstract":"Objective: Stress causes neuropsychiatric diseases such as depression and anxiety in the person by affecting emotions, opinions and behaviors. In this study, the aim was to investigate the therapeutic effects of tDCS on depression and anxiety disorders that occur after sub-chronic stress. Methods: 40 male Wistar rats weighing 290-310 g were divided into four groups as control, tDCS, stress and stress+tDCS. Restraint stress was applied for 7 days (2 h/day) as a stress model. Rats in the tDCS and stress+tDCS groups were performed the stimulation of 1 mA anodal tDCS for three consecutive days from the 5th day of stress exposure. On the 7th day of the experiment, the anxiety and depression behaviors of the rats were evaluated ANKSIYETE BOZUKLUKLARI indicator of anxiety (p<0.001). In the stress + tDCS group compared to the control group, there was a significant decrease in the data indicator of anxiety following tDCS application (p <0.05), but no significant difference was found in the results of locomotor activity. Conclusion: In conclusion, our data showed that tDCS stimulation may have an effect on sub-chronic stress-induced anxiety and","PeriodicalId":35553,"journal":{"name":"Turk hijiyen ve deneysel biyoloji dergisi. Turkish bulletin of hygiene and experimental biology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70675562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The use of fungi for the production of biotechnological products in the field of health","authors":"Şule Aybüke Yavuz, Ü. Gül","doi":"10.5505/turkhijyen.2022.06982","DOIUrl":"https://doi.org/10.5505/turkhijyen.2022.06982","url":null,"abstract":"Biotechnology is an interdisciplinary science that aims to produce products of high economic value using biological materials. Fungi are used as a source in many industrial processes such as the production of enzymes, vitamins, polysaccharides, polyhydric alcohols, pigments, lipids and glycolipids. These products are potentially valuable in terms of biotechnological studies as well as the economic value provided by their commercial production. The first biotechnological products include alcoholic beverages such as wine and beer also, basic nutrients such as bread and cheese produced by the use of yeast and fungi. Especially with the discovery of the first antibiotic, the possibilities of using fungi for the production of drugs and similar substances in health biotechnology have been started to be investigated. Fungal secondary metabolites are extremely important for our health and nutrition and also have a significant economic impact. In recent years, modified organisms have been used in biotechnological production as a result of the use of techniques developed by molecular biology and genetic studies. Today, there has been a significant increase in production and marketing activities for microbial enzymes and pharmaceutical üretimi ürünler ticari üretimleriyle mantarlar, sağlık products produced by recombinant DNA technology, including yeasts and other fungi as hosts. Today, fungal biology is an important participant in the global industry. Genomic and proteomic studies on newly discovered species are ongoing. The aim of this study is to examine the information in the literature about the use of fungi in health biotechnology. According to the results of this study, yeasts and fungi are widely used in health biotechnology, especially in the production of pharmaceutical products. Fungi and yeasts are used in the production of various pharmaceutical products such as antitumor and antimicrobial drug active substances, vaccines and hormones. In addition, it has been determined that new fungi and yeast species developed using recombinant DNA technologies can be used both more efficiently and effectively. In addition, the existence of newly isolated yeast and fungi species with many features not fully identified is promising for the production of new products in","PeriodicalId":35553,"journal":{"name":"Turk hijiyen ve deneysel biyoloji dergisi. Turkish bulletin of hygiene and experimental biology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70675625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Seropositivity of Mycoplasma synoviae by ELISA in commercial broiler and layer chickens","authors":"G. Goncagül, E. Günaydın, Özlem Kardoğan, Yavuz Çokal","doi":"10.5505/turkhijyen.2022.20846","DOIUrl":"https://doi.org/10.5505/turkhijyen.2022.20846","url":null,"abstract":"","PeriodicalId":35553,"journal":{"name":"Turk hijiyen ve deneysel biyoloji dergisi. Turkish bulletin of hygiene and experimental biology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70675771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of biological and chemical weapons in the scope of the pandemic process and the measures to be taken","authors":"A. Arslan, Ö. Barış","doi":"10.5505/turkhijyen.2022.41017","DOIUrl":"https://doi.org/10.5505/turkhijyen.2022.41017","url":null,"abstract":"Biological attack or bioterrorism is one of the sides to cause disease or death in all living things by using biological causative agents of disease due to reasons such as political, ideological and economic. There were many biological attacks from the primitive ages when poisoned arrows were used to the use of anthrax spores in 2001 against USA. Although chemical attacks are not as deep-rooted as biological attacks, they have been used for a long time, but the period when they came to the stage of history was the 19th century with the development of the modern chemical industry. Chemical attacks caused injuries, permanent damage and death to many people especially during the period of World wars. The pandemic that can be caused by natural epidemic diseases is the spread of a factor or disease in a very wide area. With the spread of disease;panic, unrest and chaos environment occurs in the spreading area. Coronavirus (Covid-19), which causes the current pandemic, is the most recent example. Coronavirus out broke in Wuhan, China, and started to spread in China first, and then Iran, and had an impact on Italy as well as European continent and around the world with the American continent. It infected millions of people, hundreds of thousands of people died, and caused environmental, social, psychological and economic problems on a global scale. Recently, different pandemic processes related to influenza have been experienced, but states have not been able to demonstrate an effective and efficient defense against the new type of coronavirus since the necessary preparations were not made despite the death of millions of people. Since biological attack and natural epidemics have the same effects and characteristics, it is not possible to predict how the states will respond in a possible biological attack. As in the current pandemic process, the possible consequences that will arise when caught unprepared are doubtful. In this study, it is evaluated how biological agents and natural epidemics are similar to each other and how to take measures against a possible attack or a new disaster. © 2022,Turk Hijyen ve Deneysel Biyoloji Dergisi.All Rights Reserved.","PeriodicalId":35553,"journal":{"name":"Turk hijiyen ve deneysel biyoloji dergisi. Turkish bulletin of hygiene and experimental biology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70676631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Elevated serum homocitrulline levels in patients with peripheral artery disease","authors":"Duygu Eryavuz Onmaz, C. Aydoğan, Nazif Aygül, A. Sivrikaya, S. Abuşoğlu, A. Ünlü","doi":"10.5505/turkhijyen.2022.76402","DOIUrl":"https://doi.org/10.5505/turkhijyen.2022.76402","url":null,"abstract":"","PeriodicalId":35553,"journal":{"name":"Turk hijiyen ve deneysel biyoloji dergisi. Turkish bulletin of hygiene and experimental biology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70677626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How to detect SARS-CoV-2: A brief review about molecular diagnosis techniques","authors":"A. Carhan, Ender Şimşek, Özen Özensoy Güler","doi":"10.5505/turkhijyen.2022.87533","DOIUrl":"https://doi.org/10.5505/turkhijyen.2022.87533","url":null,"abstract":"A new type of coronavirus (SARS-CoV-2) was detected in patients with acute respiratory disease in 2019. SARS-CoV-2 is a virus that can cause fever, dry cough, shortness of breath, anorexia, fatigue and sore throat, which can be transmitted through respiration and has started to spread around the world and has become a global problem. The disease caused by SARS-COV-2 has been named Coronavirus Disease 2019 (Covid-19) by the World Health Organization (WHO). According to the WHO, Covid-19 is a pandemic and it is stated that humanity has not experienced such an epidemic in the last hundred years. The coronavirus originated from bats and was transmitted to human through unknown animals in Wuhan province of China in December 2019. On January 2021, 96.658.420 confirmed cases and 2.092.062 deaths have occurred in the world. There is a growing need in the detection of SARS-CoV-2. A number of problems and difficulties are observed in the diagnosis and treatment of Covid-19. Chest tomography and molecular tests are used to detect SARS-CoV-2. The molecular techniques used are PCR-based and non-PCR-based methods. Usually detection of SARS-CoV-2 is based on PCR, but isothermal nucleic acid amplification tests have also been promising alternatives. Currently, qRT-PCR is a golden assay and it is widely used although many alternative assays have been developed for recent years. The current testing capacity and availability can not meet the unprecedented global demands for rapid, reliable and widely accessible molecular diagnosis. In addition, there is a need for a comprehensive strategy compare the molecular techniques used in the field. Since in this review we aim to give a summary of molecular diagnosis techniques to detect Covid 19 © 2022, Turk Hijyen ve Deneysel Biyoloji Dergisi. All Rights Reserved.","PeriodicalId":35553,"journal":{"name":"Turk hijiyen ve deneysel biyoloji dergisi. Turkish bulletin of hygiene and experimental biology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70677866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular characterization and determination of risk factors of sheep-associated Ovine gammaherpesvirus-2 in cattle","authors":"M. Timurkan, N. Ulaş, H. Aydın, Ş. Değirmençay","doi":"10.5505/turkhijyen.2022.95777","DOIUrl":"https://doi.org/10.5505/turkhijyen.2022.95777","url":null,"abstract":"Objective: Malignant catarrhal fever (MCF), is a sporadic disease with high mortality caused by a group of viruses that are classified in Herpesviridae , in subfamily Gammaherpesvirinae and genus Macavirus . and Ovine gammaherpesvirus-2 (OvHV-2), are two pathogens close results fatal close to We used chain to from PCR were sequenced and raw data of referance sequences were compared to references previously recorded to GenBank. Phylogenetic analysis was performed with MEGA 5.0 software. Results: After PCR analysis of blood and swab samples, targeting the tegument protein coding region of OvHV-2, an amplicon of 422-bp was obtained. Sequencing and phylogenetical analyses revealed that OvHV-2 strain in this study was closely related to India, Egypt and Iraq strains and relatively distant to German, Canadian, Brazilian and African strains. Conclusion: We conclude that, in Muslim countries unregulated animal markets which are formed during the Festival of Sacrifice have a significant risk of spread for OvHV-2 and different species should not be sold together in these areas.","PeriodicalId":35553,"journal":{"name":"Turk hijiyen ve deneysel biyoloji dergisi. Turkish bulletin of hygiene and experimental biology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70677961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of the COVID-19 pandemic on tuberculosis control in Mersin province","authors":"G. Aslan, Harun Gülbudak, N. Delialioğlu, Hamide Kaya, Asena Ayça Özdemir","doi":"10.5505/turkhijyen.2022.88965","DOIUrl":"https://doi.org/10.5505/turkhijyen.2022.88965","url":null,"abstract":"Objective: All resources of the health system have been allocated to the pandemic to combat the coronavirus disease (COVID-19) epidemic that has affected the world. In addition, measures implemented during the pandemic, such as isolation, lockdown and restricted mobility, adversely affected tuberculosis (TB) control programs in our country and around the world. In this study, it was aimed to investigate the effect of the COVID-19 pandemic on TB patients and TB control program in Mersin province. Methods: In this study, a total 6328 samples of 3731 patients with a preliminary diagnosis of TB, from Mersin University Hospital and Mersin tuberculosis dispensaries, between January 2019 and December 2020, were included. In the study, how much the number of samples decreased during the 2020 pandemic period, the number of patients diagnosed with TB, the change in the age distribution of the patients, and the number of control samples from the treatment follow-up of TB patients were examined. Results: In the study, a decrease of 42.2% in the number of patients and a decrease of 45.4% in the number of samples were observed during the pandemic period of 2020.The highest decrease in the number of patients by months were observed in March, April and May (respectively 44.2%, 67.2% and 69.8%) when the pandemic started in our country and the restrictions were applied intensively. During the pandemic period, a decrease of 28.2% was observed in the number of TB positive patients. While the mean age of TB positive patients was 53.5±16.2 in 2019, it decreased to 40.3±19.6 years in 2020, and the decrease in the mean age was statistically significant (p <0.001). When the age groups between years are compared;While the rate of patients over 65 years of age was higher in 2019, the rate of patients under the age of 18 was found to be higher in 2020 (p=0.003). In the study, control samples came during treatment follow-up from 73% of TB patients in 2019 and 52.9% in 2020. The rate of decrease in the number of patients with control samples from TB positive patients during the pandemic period was found to be statistically significant (p=0.021). Conclusion: The findings of our study revealed that the restrictions applied during the pandemic period adversely affected the diagnosis and follow-up of TB in our region. In addition, the decrease in the average age of TB patients and the tendency towards younger age and the increase in the number of positive patients under the age of 18 suggest that intra-familial transmission increased in this period. © 2022,Turk Hijyen ve Deneysel Biyoloji Dergisi,All rights reserved","PeriodicalId":35553,"journal":{"name":"Turk hijiyen ve deneysel biyoloji dergisi. Turkish bulletin of hygiene and experimental biology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70677985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluate the effects of rosmarinic acid in ovariectomized rats: urethane-induced cortical oscillations","authors":"Deniz Kantar, Alev Duygu Acun, H. Er","doi":"10.5505/turkhijyen.2022.68815","DOIUrl":"https://doi.org/10.5505/turkhijyen.2022.68815","url":null,"abstract":"","PeriodicalId":35553,"journal":{"name":"Turk hijiyen ve deneysel biyoloji dergisi. Turkish bulletin of hygiene and experimental biology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70677049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vitamin B12 Alleviates Methotrexate-Induced Lung Injury In Rat: A Histopathological, Immunohistochemical, And Biochemical Study","authors":"E. Kaymak, D. Karabulut, E. Öztürk, A. Akin, N. Kuloğlu, B. Yakan","doi":"10.5505/turkhijyen.2022.00947","DOIUrl":"https://doi.org/10.5505/turkhijyen.2022.00947","url":null,"abstract":"ÖZET Amaç: Metotreksat (MTX) önemli bir kemoterapötik olup kanser hastalarında kullanılan önemli bir antikanserojen olmakla birlikte diğer dokularda yan etkilere yol açmaktadır. Bu yan etkiler arasında akciğer toksisitesi de yer almaktadır. B12 Vitamini güçlü bir antioksidandır ve reaktif oksijen türlerinin azalmasını sağlar. Bu çalışma, B12 vitamininin sıçan akciğerinde metotreksat kaynaklı hasara karşı koruma sağlayıp sağlayamayacağını belirlemek için tasarlanmıştır.","PeriodicalId":35553,"journal":{"name":"Turk hijiyen ve deneysel biyoloji dergisi. Turkish bulletin of hygiene and experimental biology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70675489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}