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2020 IEEE Integrated STEM Education Conference (ISEC)最新文献

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Rapid Thickness Identification Methodology For Two-Dimensional MoS2 and In2 Se3 Nanosheets Using Optical Microscopy 二维MoS2和In2 Se3纳米片的光学显微镜快速厚度鉴定方法
Pub Date : 2020-08-01 DOI: 10.1109/ISEC49744.2020.9397826
Darren Wu, Qiu Li, Feifan Wang, Tiantian Li, Tingyi Gu
Problem StatementCurrently, identification methods for the thickness measurement of nanomaterials demand expensive and nonstandard equipment, impairing its continued study, practical applications, and industrial commercialization.The development of a novel and accurate thickness identification methodology is imperative for the continued study and potential commercialization of two-dimensional (2D) materials. Through experimentation, an effective and straightforward methodology has been produced for the thickness identification of MoS2 and In2 Se3 nanosheets on 300nm Si/SiO2 under optical microscopy from approximately single to decuple layer numbers. The optical contrast difference values of the atomically-thin nanostructures were collected throughout and arranged into a standard reference index which was correlated to height number in nanometers. Using this method, the thickness of a substance could be simply and accurately determined without the use of complex instrumentation, experimental setup, and calculation, therefore, saving time and financial costs.
目前,用于纳米材料厚度测量的识别方法需要昂贵和非标准的设备,这损害了其继续研究,实际应用和工业商业化。开发一种新颖而准确的厚度识别方法对于二维材料的持续研究和潜在的商业化是必不可少的。通过实验,建立了一种在光学显微镜下从大约单层数到十层数鉴定300nm Si/SiO2上MoS2和In2 Se3纳米片厚度的有效和简单的方法。自始至终收集原子薄纳米结构的光学对比差值,并将其排列成与纳米高度数相关的标准参考指数。使用该方法,可以简单、准确地测定物质的厚度,而无需使用复杂的仪器、实验装置和计算,从而节省了时间和财务成本。
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引用次数: 0
Integrating a Smartphone-Based Vibration Experiment into an Engineering Course 将基于智能手机的振动实验融入工程课程
Pub Date : 2020-08-01 DOI: 10.1109/ISEC49744.2020.9280731
M. Jouaneh
A smartphone coupled with a low-cost physical system can be used to conduct a meaningful at-home engineering experiment that provides an environment for experiential and personalized learning. The objective of this study is to improve students’ understanding of the response of a dynamic system through integrating an at-home experiment into a lecture-only class using a smartphone as the measurement system. The paper reports on the use of the linear acceleration sensor in smartphones to conduct an at-home experiment to measure the vibration characteristics of a cantilever beam in a junior-level, systems dynamic course. All students in the class were provided with a spring steel beam and a C-shaped clamp. The students mounted their own phone at the end of the beam, and an app was used to record the acceleration of the beam for three different beam lengths. From the experimental data, the students were asked to determine the damped natural frequency of the beam and compare it to theory. The study was performed over three years with a total of 302 students. Data analysis of the short pre and post quiz conducted with the experiment showed that the at-home experiment had a positive effect on students’ understanding of key concepts. Furthermore, written and verbal comments from the students showed that the students valued the learning they got from performing this experiment.
智能手机与低成本的物理系统相结合,可以用于进行有意义的家庭工程实验,为体验和个性化学习提供环境。本研究以智能手机为测量系统,通过将家庭实验整合到课堂中,以提高学生对动态系统响应的理解。本文报道了在智能手机中使用线性加速度传感器进行家庭实验,以测量初级系统动态过程中悬臂梁的振动特性。班上所有学生都有一个弹簧钢梁和一个c形夹具。学生们将自己的手机安装在光束的末端,并使用一个应用程序来记录三种不同光束长度下光束的加速度。根据实验数据,学生们被要求确定梁的阻尼固有频率,并将其与理论进行比较。这项研究历时三年,共有302名学生参与。对实验前后的小测验数据分析表明,家庭实验对学生对关键概念的理解有积极的影响。此外,学生们的书面和口头评论表明,学生们很重视他们从这个实验中学到的东西。
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引用次数: 1
Quality Control of Brand Name Aspirin drug and Generic Aspirin drug 阿司匹林品牌药与非专利药的质量控制
Pub Date : 2020-08-01 DOI: 10.1109/ISEC49744.2020.9397816
Jiale Lu
Brand name drug is developed and produced by the brand name drug company through a complicated process. A new drug has to pass the following steps to be brought to the public: discovery, delivery, and manufacturing. A new compound needs to be found to fit the chemistry and physical characteristics. The dosage form of a suitable compound is then developed. The routes of administration are tested and dosage duration is optimized. The drug needs to be delivered into the targeted area at a certain rate in the environment in the human body. The active ingredient needs to be combined with other inactive ingredients for the easier manufacturing process as well as better absorption, distribution, metabolism, excretion and lower toxicity. The last part is the manufacturing part, which involves the development of the manufacturing process on a larger scale as well as getting approval from the FDA and testing results for pre-clinical and clinical tests. The company holds on the patent for the drug and the manufacturing process for 10 years, usually about the same period as the developing process. After the original patent expires, other generic drug companies can produce generic drugs (1). FDA requires the generic drug producer to prove that the drug they produce could have the same or comparable clinic effect as the brand name drug (2). The generic drugs are produced based on the concept of bioequivalence, meaning that the product should meet the same or comparable effect when the same number of active ingredients in the same dosage form and under the same route of administration is used (3). The 1984 Drug Price Competition and Patent Term Restoration Act stopped the requirement for performing pre-clinical and clinical tests all the generic copied drugs because the bioequivalence allows the generic drug to have the same performance in the pre-clinical and clinical tests. There are certain differences between generic drugs and brand name drugs. The shape, inactive ingredient, packing methods, color, and flavoring may be different between the generic drug and brand name drugs to prevent violation against trademark laws (5).
名牌药品是由名牌药品公司经过一个复杂的工艺过程开发生产的。一种新药必须经过以下几个步骤才能推向公众:发现、交付和制造。需要找到一种符合化学和物理特性的新化合物。然后研制出合适化合物的剂型。试验了给药途径,优化了给药时间。药物需要在人体内的环境中以一定的速率输送到靶区。有效成分需要与其他非活性成分结合,以便更容易制造过程,更好的吸收,分布,代谢,排泄和降低毒性。最后一部分是生产部分,包括大规模生产工艺的开发,获得FDA的批准以及临床前和临床试验的测试结果。该公司拥有药物和制造过程的专利10年,通常与开发过程大致相同。原专利到期后,其他仿制药公司可以生产仿制药(1)。FDA要求仿制药生产商证明他们生产的药物可以具有与品牌药相同或相当的临床效果(2)。仿制药是基于生物等效性的概念生产的。这意味着在相同剂型和相同给药途径下使用相同数量的活性成分时,产品应达到相同或可比的效果(3)。1984年《药品价格竞争和专利期限恢复法案》停止了对所有仿制仿制药进行临床前和临床试验的要求,因为生物等效性允许仿制药在临床前和临床试验中具有相同的性能。仿制药和品牌药有一定的区别。仿制药和品牌药的形状、非活性成分、包装方法、颜色和风味可能不同,以防止违反商标法(5)。
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引用次数: 1
A Study of the Localization Methods to Help Elderly Patients in their Home Environments 居家环境中帮助老年患者的定位方法研究
Pub Date : 2020-08-01 DOI: 10.1109/ISEC49744.2020.9397825
A. Ali, Jennifer S. Suon, M. A. Yousuf
Patients with various movement hampering illnesses who have been admitted to hospitals are at low risk of being injured as they are under strict observation by hospital staff and electronic systems. However, once these patients move into their homes, it becomes difficult to monitor them and warn them of potential hazards. For example, Chronic Obstructive Pulmonary Disease (COPD) is a group of progressive lung diseases that obstruct airflow. It affects millions of adults in the USA alone, with a world estimate of 64 million by the World Health Organization. COPD patients have breathing apparatus attached to their mouth, which is then connected to oxygen tanks via pipes. These individuals run into various problems such as walking too far away from the tank, tripping over the plastic pipes, etc. Most of these patients have limited resources to invest in expensive tracking devices, or to get personalized help at home. To solve some of these problems, one must first be able to reliably locate them and keep track of them at all times. The objective of this work is to propose a comprehensive, multi-sensor platform that can be reliably installed at homes. We explore a variety of low-cost tools and techniques available. This includes satellite tracking of cell phones attached to the patient, ultrasound and laser range finders mounted on walls, iBeacons, etc. We also discuss some of the fancier tools on the horizon, which may soon be available for household applications.
因患有各种活动障碍疾病而入院的患者,在医院工作人员和电子系统的严密监视下,受伤的风险很低。然而,一旦这些病人搬进自己的家,就很难对他们进行监控,并警告他们潜在的危险。例如,慢性阻塞性肺疾病(COPD)是一组阻碍气流的进行性肺部疾病。仅在美国就有数百万成年人受到影响,世界卫生组织估计全球有6400万成年人。慢性阻塞性肺病患者的口腔上装有呼吸器,然后通过管道与氧气罐相连。这些人会遇到各种各样的问题,比如走得离水箱太远,被塑料管绊倒等等。这些患者大多财力有限,无法购买昂贵的追踪设备,也无法在家中获得个性化的帮助。要解决其中一些问题,首先必须能够可靠地定位它们并随时跟踪它们。这项工作的目的是提出一个全面的,多传感器平台,可以可靠地安装在家里。我们探索了各种低成本的工具和技术。这包括用卫星跟踪病人身上的手机、安装在墙上的超声波和激光测距仪、iBeacons等。我们还讨论了一些即将出现的更新奇的工具,这些工具可能很快就可以用于家庭应用。
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引用次数: 0
Using Text Data Mining to Enhance the Literature Search Process for Novice STEM Researchers 利用文本数据挖掘提高STEM新手的文献检索过程
Pub Date : 2020-08-01 DOI: 10.1109/ISEC49744.2020.9397851
A. Fortino, Qitong Zhong, Luke Yeh, Sijia Fang
A literature search can be an arduous process, especially for novice researchers. We have developed a tool that allows a researcher to rank order a list of references that are returned by a keyword-based search engine, based on similarity to known exemplars. This significantly accelerates literature searches by novices. Our research question was: can we produce a text-analytic tool that, when used by an inexperienced scholar, rank-orders a list of references against an exemplar, so that the time needed to find relevant literature is reduced, and the literature survey section of their paper will be superior. An experiment was set up where one course section used the tool to produce the literature review section of a thesis proposal, and the other class used traditional literature research tools. We surveyed both sections to self-report the time used for the literature search. We found some time savings by some of the students using the tool. We also provided blind, randomly selected pairs of completed proposals to SME faculty who teach that same class to assess the quality of the literature sections of the samples. We found that the tool-using section of students reported significantly less time to do the literature search, and the quality of their literature review produced had a significantly higher quality.
文献检索可能是一个艰巨的过程,特别是对新手研究人员。我们开发了一个工具,允许研究人员根据与已知范例的相似性,对基于关键字的搜索引擎返回的参考文献列表进行排序。这大大加快了新手的文献搜索。我们的研究问题是:我们是否可以制作一个文本分析工具,当一个没有经验的学者使用时,可以根据范例对参考文献列表进行排序,从而减少查找相关文献所需的时间,并且他们论文的文献调查部分将会更好。我们设置了一个实验,其中一个课程部分使用该工具来制作论文开题的文献综述部分,而另一个班级使用传统的文献研究工具。我们调查了这两个部分,以自我报告用于文献检索的时间。我们发现一些学生使用这个工具节省了一些时间。我们还提供了盲的,随机选择的完成的提案对中小企业教师谁教同一类评估样本的文献部分的质量。我们发现,使用工具的学生在文献检索上花费的时间显著减少,他们的文献综述质量显著提高。
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引用次数: 0
Best Predictors for Major Food Allergy Reactions 主要食物过敏反应的最佳预测指标
Pub Date : 2020-08-01 DOI: 10.1109/isec49744.2020.9397858
Will R Morrison
I have recently received a dataset with information about 680 Children’ s Hospital of Philadelphia food challenges and whether they had a severe reaction or a mild reaction. Food challenges are appointments where a child is given a food that he has been tested to have a small or nonexistent allergy for to see if they will react. If they don’t, they are cleared of the allergy and can eat it outside of the controlled environment. In each of the 680 tests in this dataset the child reacted and data was recorded about the type of food, how much they ate, how they reacted to it, and how severe the reaction was based on a standardized scale. The goal with this data is to find out which of the 20 + columns is the best predictor for whether someone will have a severe reaction. For example, does a history of asthma make someone more likely to have a severe reaction? Or does sneezing during the test mean that they will have a severe reaction. So far, I have done a logistic regression with the data. Some findings have surfaced, but for the final project I would need to find what variables to drop and focus on analyzing the results. Below are some screenshots of the data and work that I have done with it: The first few entries in the dataset https://i.imgur.com/TEl2ms3.png A heatmap of the variables to determine which need to be dropped https://i.imgur.com/qjZ1FLU.png
我最近收到了一个数据集,其中包含680名费城儿童医院的食物挑战以及他们是否有严重或轻微的反应。食物挑战是指给孩子一种他已经被测试有轻微过敏或不存在过敏的食物,看看他们是否会有反应。如果没有,他们的过敏症就被清除了,可以在受控环境外食用。在这个数据集中的680个测试中,每一个测试都记录了孩子的反应,并记录了关于食物类型、他们吃了多少、他们对食物的反应以及基于标准化尺度的反应程度的数据。这些数据的目的是找出20多个列中哪一列最能预测某人是否会有严重的反应。例如,有哮喘史的人更有可能产生严重的反应吗?或者在测试过程中打喷嚏是否意味着他们会有严重的反应?到目前为止,我已经对数据进行了逻辑回归。一些发现已经浮出水面,但对于最终项目,我需要找到要删除的变量并专注于分析结果。下面是数据的一些屏幕截图和我对它所做的工作:数据集中的前几个条目https://i.imgur.com/TEl2ms3.png用于确定需要删除哪些变量的热图https://i.imgur.com/qjZ1FLU.png
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引用次数: 1
A social engineering awareness and training workshop for STEM students and practitioners 为STEM学生和从业者提供的社会工程意识和培训研讨会
Pub Date : 2020-08-01 DOI: 10.1109/ISEC49744.2020.9280596
Aunshul Rege, T. Nguyen, Rachel Bleiman
The human element is often regarded as the weakest link in cybersecurity, yet awareness and training efforts focus primarily on the technical aspects of cybersecurity and downplay the relevance of the human factor. One way to exploit this human vulnerability is through social engineering, in which cybercriminals utilize persuasion and manipulation of human behavior and psychology to convince individuals to reveal information, provide access or perform an action. This paper offers a case study on efforts to design and develop a social engineering awareness and training program that was implemented at the 2019 National Science Foundation Cybersecurity Summit using the National Institute of Standards and Technology framework for program development. This program was developed to enhance the ability for individuals in the future and current workforce to protect their organization against vulnerabilities to social engineering attacks, through corresponding awareness and training. The authors share the different stages that are involved in producing a successful program: designing the program, developing the awareness and training material, and implementing the program. In addition, this paper details the challenges and lessons the authors experienced and learned, which can be used as a guide for other practitioners to develop social engineering awareness and training programs.
人的因素通常被认为是网络安全中最薄弱的环节,然而意识和培训工作主要集中在网络安全的技术方面,而低估了人的因素的相关性。利用这一人类弱点的一种方法是通过社会工程,网络罪犯利用说服和操纵人类行为和心理来说服个人透露信息、提供访问权限或执行某项行动。本文提供了一个案例研究,介绍了在2019年国家科学基金会网络安全峰会上使用国家标准与技术研究所框架进行计划开发的社会工程意识和培训计划的设计和开发工作。该计划旨在通过相应的意识和培训,提高个人和当前劳动力的能力,以保护他们的组织免受社会工程攻击的脆弱性。作者分享了制定一个成功的计划所涉及的不同阶段:设计计划,开发意识和培训材料,以及实施计划。此外,本文还详细介绍了作者所经历和学习到的挑战和教训,可以作为其他实践者发展社会工程意识和培训计划的指南。
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引用次数: 0
Efficiency of organic deodorizer in removing foul smell in shoes 有机除臭剂去除鞋子异味的效果
Pub Date : 2020-08-01 DOI: 10.1109/ISEC49744.2020.9397852
B. Sebastian, Alejandro C. Javier, Ryan F. Chua, Byron D. Traje
Bromodosis or foot odor affects many people around the world. Shoe deodorizers are used to prevent the malodor, but most of the products available may use harmful materials that do not fully eliminate its cause. These products contain substances that degrade the environment (Steinmann, 2016), and pose as a health hazard (Engelund, et al., 2005). The researchers plan to utilize natural materials (activated charcoal and freeze-dried lemon) in creating a shoe deodorizer that can eliminate the cause of foot odor while reducing ecological footprint. Based on previous studies, foot odor was released from Isovaleric acid, which is the result of Staphylococcus epidermidis breaking-down leucine present in sweat (Ara, et al., 2006). When the bacteria in feet eat amino acids such as leucine, it produces a by-product called Isovaleric acid which causes the foul smell. Various studies have also been made regarding the use of lemon and activated charcoal to reduce foul smell (Otang & Afolavan 2016, Tada, et al., 2016). The researchers will focus on the effectiveness of freeze-dried Citrus limon, (Lisbon quad variety) in removing malodor. A revised version of the Modified Kirby Bauer disc diffusion test method was done by the Industrial Technology Development Institute, Department of Science and Technology (ITDI-DOST. The researchers were able to verify the antibacterial properties of freeze-dried lemons. Results showed that the sample freeze–dried lemons (10mm), produced complete inhibitory activity with a Total Mean of Inhibition of 12.74mm, with mild reactivity against the test organism Staphylococcus aureus, a common specie of the normal microbiota of the skin. It was concluded from the research that freeze-dried lemons have a good potential to inhibit foul smell, and may be an effective ingredient for a shoe deodorizer.
臭脚病或足臭影响着世界各地的许多人。鞋子除臭剂是用来防止异味的,但大多数可用的产品可能使用有害材料,不能完全消除其原因。这些产品含有降解环境的物质(Steinmann, 2016),并构成健康危害(Engelund, et al., 2005)。研究人员计划利用天然材料(活性炭和冻干柠檬)制造出一种除臭剂,既能消除脚臭的原因,又能减少生态足迹。根据以往的研究,脚臭是由异戊酸释放的,这是表皮葡萄球菌分解汗液中存在的亮氨酸的结果(Ara, et al., 2006)。当脚上的细菌食用亮氨酸等氨基酸时,会产生一种叫做异戊酸的副产物,从而产生臭味。关于使用柠檬和活性炭来减少恶臭也进行了各种研究(Otang & Afolavan 2016, Tada等人,2016)。研究人员将重点研究冻干柑橘柠檬(里斯本quad品种)去除异味的有效性。科学技术部工业技术发展研究所(ITDI-DOST)对改良Kirby Bauer圆盘扩散试验方法进行了修订。研究人员能够验证冻干柠檬的抗菌特性。结果表明,样品冻干柠檬(10mm)产生完全的抑制活性,总平均抑制量为12.74mm,对皮肤正常微生物群中常见的金黄色葡萄球菌具有轻微的反应性。研究结果表明,冻干柠檬具有良好的抑臭潜力,可作为一种有效的除臭剂。
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引用次数: 0
Student Performance Prediction from E-mail Assessments Using Tiny Neural Networks 利用微型神经网络从电子邮件评估中预测学生成绩
Pub Date : 2020-08-01 DOI: 10.1109/ISEC49744.2020.9397817
N. Yadav, Kajal Srivastava
Predicting student performance using e-mail assessments can help in early interventions to better assist students sooner, rather than later, in STEM courses. In this paper, we propose CorC-Net, a tiny artificial neural network (ANN) that operates on limited data comprised of features scored from student assessments based on writing e-mails. ANNs are typically built using large scale data sets to truly realize their full potential; however, tiny neural networks overcome this problem by utilizing smaller batches of data making them easier to train. COrC-Net uses scored e-mails for content, organization, and clarity and classifies how students will perform. Formative instructor feedback provided between the assessments implies that CorC-Net is a more logical fit to simulate the “learning” process when human reaction to feedback and corrective action is involved. This is true especially in sequential course assessment tasks. In this paper, we show that COrC-Net outperforms other multiclass classification algorithms like decision trees, support vector machines, Gaussian Naive Bayes, and K-nearest neighbors. CorC-Net’s success in classifying student performance shows great potential in courses where longterm temporal assessment data is not available.
使用电子邮件评估预测学生的表现可以帮助早期干预,更好地帮助学生尽早而不是晚些学习STEM课程。在本文中,我们提出了CorC-Net,这是一个微小的人工神经网络(ANN),它运行在有限的数据上,这些数据由基于写电子邮件的学生评估评分的特征组成。人工神经网络通常使用大规模数据集构建,以真正发挥其全部潜力;然而,微型神经网络通过使用更小批量的数据来克服这个问题,使它们更容易训练。COrC-Net对邮件的内容、组织和清晰度进行评分,并对学生的表现进行分类。在评估之间提供的形成性教师反馈表明,当涉及到人类对反馈和纠正行动的反应时,CorC-Net更符合逻辑地适合模拟“学习”过程。这在连续的课程评估任务中尤其如此。在本文中,我们证明了COrC-Net优于其他多类分类算法,如决策树、支持向量机、高斯朴素贝叶斯和k近邻。CorC-Net在对学生成绩进行分类方面的成功显示了在无法获得长期评估数据的课程中巨大的潜力。
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引用次数: 3
Uncovering the Genetics behind Alzheimer’s Disease and Sleep: A Co-expression and Evolutionary Analysis 揭示阿尔茨海默病和睡眠背后的遗传学:共同表达和进化分析
Pub Date : 2020-08-01 DOI: 10.1109/ISEC49744.2020.9397833
Sihan Fei, Zeqing Li
Alzheimer’s disease is a fatal form of dementia, and it caused over 120 thousand deaths in the U.S. alone in 2017. Recent studies indicate that sleep deprivation is both a cause and an effect of Alzheimer’s disease. Our research investigates the correlation between sleep deprivation and Alzheimer’s disease through two stages. In the first stage of the research, the genetic coexpression of Alzheimer’s disease-related genes (A-genes) and sleep-related genes (S-genes) across different stages of human development is explored. A general correlation between the expression of these two sets of genes is confirmed and strongly correlated A-gene and S-gene pairs are located, including GATA1 & ALAS2, TF & MOG, etc. In the second stage of the research, the expressions of A-genes and S-genes across different species are compared. Genes with unusual expression patterns in humans compared to those in other primate species are identified, hinting at possible genetic pathways key to solving the mystery of Alzheimer’s disease.
阿尔茨海默病是一种致命的痴呆症,2017年仅在美国就造成了12万多人死亡。最近的研究表明,睡眠不足既是阿尔茨海默病的原因,也是其结果。我们的研究通过两个阶段调查了睡眠剥夺与阿尔茨海默病之间的关系。在研究的第一阶段,探索阿尔茨海默病相关基因(a基因)和睡眠相关基因(s基因)在人类不同发育阶段的基因共表达。证实了这两组基因的表达具有普遍的相关性,并找到了相关性较强的A基因和s基因对,包括GATA1 & ALAS2, TF & MOG等。在研究的第二阶段,比较不同物种间a基因和s基因的表达。与其他灵长类动物相比,人类具有不同寻常表达模式的基因被识别出来,暗示了可能的遗传途径,这是解决阿尔茨海默病之谜的关键。
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引用次数: 0
期刊
2020 IEEE Integrated STEM Education Conference (ISEC)
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