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Medical Journal of Clinical Trials & Case Studies最新文献

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Unusual Penetrating, Retained Cardiac Intramural Foreign Body: Case Report 异常穿透性心脏壁内异物1例报告
Pub Date : 1900-01-01 DOI: 10.23880/mjccs-16000308
Mohamed Abdelwahab Alassal
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引用次数: 0
Frequency of Anencephaly in All Pregnant Population: An Observational Study 无脑畸形在所有怀孕人群中的发生率:一项观察性研究
Pub Date : 1900-01-01 DOI: 10.23880/mjccs-16000267
Madeeha Subhan Waleed
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引用次数: 0
Thalidomide Life Threatening Hypokalemia 沙利度胺危及生命的低血钾
Pub Date : 1900-01-01 DOI: 10.23880/mjccs-16000265
Madeeha Subhan Waleed
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引用次数: 0
Treatment with Oseltamivir in Early Suspected Cases of COVID19 奥司他韦治疗早期疑似covid - 19病例
Pub Date : 1900-01-01 DOI: 10.23880/mjccs-16000s1-001
Rawa Jaafar Kadhim Al-Ameri
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引用次数: 0
Impact of Lung Nodules on LDCT on Smoking Cessation 肺结节对LDCT戒烟的影响
Pub Date : 1900-01-01 DOI: 10.23880/mjccs-16000226
Ankit Gupta
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引用次数: 0
Induction of Neutralizing Immunity against SARS-CoV-2 Omicron Variant by COVID-19 Vaccine Boosters COVID-19疫苗增强剂诱导对SARS-CoV-2组粒变异的中和免疫
Pub Date : 1900-01-01 DOI: 10.23880/mjccs-16000311
A. Cheepsattayakorn
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引用次数: 0
Extra Pulmonary Manifestations of COVID-19 COVID-19的肺部外表现
Pub Date : 1900-01-01 DOI: 10.23880/mjccs-16000271
Madeeha Subhan Waleed
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引用次数: 5
Comparison of Early vs Late Cholecystectomy Performed for Mild Gall Stone Pancreatitis in Terms of Mean Length of Hospital Stay 轻度胆石性胰腺炎早期与晚期胆囊切除术的平均住院时间比较
Pub Date : 1900-01-01 DOI: 10.23880/mjccs-16000303
Siddique Ahmad
American Journal of Surgery and Clinical Case Reports Research Article Open Access Comparison of Early Vs Late Cholecystectomy Performed for Mild Gall Stone Pancreatitis in Terms of Mean Length of Hospital Stay Ahmad SZ1, Ahmad S2*, Shah N3 and Ali H3 1Department of General Surgery Hayatabad Medical Complex Peshawar, Pakistan 2Associate Professor Department of General Surgery Hayatabad Medical Complex, Peshawar Pakistan 3Specialist Registrar Department of General Surgery Hayatabad Medical Complex Peshawar Pakistan
美国外科杂志和临床病例报告研究文章早期和晚期胆囊切除术治疗轻度胆石性胰腺炎的平均住院时间比较Ahmad SZ1, Ahmad S2*, Shah N3和Ali H3巴基斯坦,白沙瓦,Hayatabad综合医疗中心,普通外科专科登记处
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引用次数: 0
Efficacy of Errector Spinae Plane Block in Postoperative Pain Controle after Laparoscopic Cholecystectomy 直立脊柱平面阻滞在腹腔镜胆囊切除术后疼痛控制中的作用
Pub Date : 1900-01-01 DOI: 10.23880/mjccs-16000289
Siddique Ahmad
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引用次数: 0
Curing Systemic Lupus Erythematosus and Severe Aplastic Anemia with an Allogeneic Transplant: A Case Report and Brief Literature Review 异体移植治疗系统性红斑狼疮和严重再生障碍性贫血1例报告及简要文献回顾
Pub Date : 1900-01-01 DOI: 10.23880/mjccs-16000335
Gomez-Almaguer D
Systemic lupus erythematosus (SLE) is an autoimmune disease that can affect many organs, including the bone marrow. Aplastic anemia (AA) is a rare but serious complication of this condition. Patients with AA secondary to SLE are usually treated with immunosuppression but less is known about hematopoietic stem cell transplantation (HSCT) as a therapeutic option. We present the case of a 22-year-old Latin-American woman with a known diagnosis of SLE referred to our center due to pancytopenia. She presented joint pain, fatigue, oral ulcers, a non-scarring alopecia, and anemic syndrome. A diagnostic workup revealed severe aplastic anemia (sAA). She received immunosuppressive therapy with corticosteroids, cyclosporine, danazol, and rituximab, which led to a transient partial response. An outpatient HLA-matched related allogeneic HSCT was performed. She received 5.9 x 106 CD34+ cells/kg after conditioning with high-dose cyclophosphamide plus fludarabine and anti-thymocyte globulin. She achieved a complete response and continues in remission with no signs of graft-versus-host disease (GVHD) or SLE activity at 38 months of follow-up. Even though allogeneic hematopoietic stem cell transplantation is not defined as a first-line treatment for severe AA in SLE, the procedure resulted in the complete remission of both related autoimmune diseases in this patient.
系统性红斑狼疮(SLE)是一种自身免疫性疾病,可影响许多器官,包括骨髓。再生障碍性贫血(AA)是一种罕见但严重的并发症。继发于SLE的AA患者通常采用免疫抑制治疗,但对造血干细胞移植(HSCT)作为一种治疗选择知之甚少。我们报告一位22岁的拉丁美洲女性,因全血细胞减少症而被诊断为SLE。她表现为关节痛、疲劳、口腔溃疡、非瘢痕性脱发和贫血综合征。诊断检查显示严重再生障碍性贫血(sAA)。她接受了皮质类固醇、环孢素、那那唑和利妥昔单抗的免疫抑制治疗,导致短暂的部分反应。门诊进行hla匹配相关同种异体造血干细胞移植。在大剂量环磷酰胺加氟达拉滨和抗胸腺细胞球蛋白治疗后,接受5.9 × 106个CD34+细胞/kg。在38个月的随访中,她获得了完全缓解并持续缓解,没有移植物抗宿主病(GVHD)或SLE活动的迹象。尽管同种异体造血干细胞移植未被定义为SLE严重AA的一线治疗方法,但该手术导致该患者两种相关自身免疫性疾病完全缓解。
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引用次数: 0
期刊
Medical Journal of Clinical Trials & Case Studies
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