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Medical Journal of Clinical Trials & Case Studies最新文献

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The Nature of Modulated Redistribution of Integral Immunity as System Redefinition of Clinical Non-Responsiveness to the Antitumor Antigenicity 作为抗肿瘤抗原性临床无反应性的系统重新定义的整体免疫调节重分布的性质
Pub Date : 1900-01-01 DOI: 10.23880/mjccs-16000301
lawrence M Agius
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引用次数: 0
Problems and ways to Improve the Effectiveness of Anti-Cancer Propaganda in the Context of a Pandemic 大流行背景下提高抗癌宣传有效性的问题与途径
Pub Date : 1900-01-01 DOI: 10.23880/mjccs-16000268
Cherenkov Vg
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引用次数: 0
Pregnancy Management and Outcome in Parkinson's Disease in Riyadh, Saudi Arabia: A Case Report 沙特阿拉伯利雅得帕金森病的妊娠管理和结局:一例报告
Pub Date : 1900-01-01 DOI: 10.23880/mjccs-16000280
Alhamoud Abdullah
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引用次数: 0
Hemophagocytic Lymphohistiocytosis (HLH) - The Enigma 噬血细胞性淋巴组织细胞增多症(HLH) -谜
Pub Date : 1900-01-01 DOI: 10.23880/mjccs-16000237
R. Sareen
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引用次数: 0
A Randomized, Comparative Clinical Trial to Evaluate Efficacy and Safety of PNB-001 as Immune Modulator in Moderate COVID-19 Patients 一项评价PNB-001作为免疫调节剂对中度COVID-19患者疗效和安全性的随机对照临床试验
Pub Date : 1900-01-01 DOI: 10.23880/mjccs-16000297
E. Lattmann
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引用次数: 1
Terra Firma-Forme Dermatosis: About a Case 原发性皮肤病1例
Pub Date : 1900-01-01 DOI: 10.23880/mjccs-16000232
Asmae Sqalli Houssaini
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引用次数: 0
Outcome of Surgical Release of 1st Dorsal Compartment of the Wrist for De Quervain’s Tenosynovitis 腕部第一背间室松解术治疗De Quervain氏腱鞘炎的疗效
Pub Date : 1900-01-01 DOI: 10.23880/mjccs-16000277
Israr Ahmad
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引用次数: 2
Primary Essential Cutis Verticis Gyrata: Case Report 原发性原发性旋直性皮肤1例报告
Pub Date : 1900-01-01 DOI: 10.23880/mjccs-16000243
Sara Mai
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引用次数: 0
Comparison of Segmental Vs Total Colectomy for Treatment of Crohn’s Disease 节段性结肠切除术与全结肠切除术治疗克罗恩病的比较
Pub Date : 1900-01-01 DOI: 10.23880/mjccs-16000319
Jamshed A
Background: There is debate concerning segmental resection for Crohn's disease. Segmental resection is reportedly associated with a greater rate of re-resection as compared to total colectomy. This topic is rarely covered in studies, and postoperative functional result has never been documented. Objective: In this study, the effects of resection, postoperative symptoms, and anorectal function were examined between segmental resection and total colectomy with anastomosis. Material and Methods: This retrospective comparative study was carried out at Department of General Surgery Hayatabad Medical Complex Peshawar from July 2019 to July 2022. Total 70 patients with Crohn's disease limited to the colon or rectum underwent resection were included. Patients were grouped into one of three categories: (a) segmental disease, (b) pancolitis with rectal sparing, or (c) proctocolitis. Recurrences were identified by colonoscopy, barium enema, upper gastrointestinal tract series with small-bowel follow-through, gross examination of bowel at reoperation, or pathologic examination of tissue Results: Total 70 patients were included in the study. Age ranged between 18-65 years with a mean of 41.5 years. There were 40(57.1%) male and 30(42.9%) female, with male to female ratio of 1.3:1. Most common presenting symptoms were pain, diarrhea and anorectal complaints. Initial diagnosis was made through colonoscopy/endoscopy in 50(71.4%) patients and by radiological study in 20(28.6%) patients. Patients were equally divided into 2 groups i.e. group 1 & 2 (35 patients in each group). Group 1 consisted total abdominal colectomy patients while group 2 comprise segmental resection patients. The sites of the cancer occurrence were similar between the two groups, i.e. the proximal colon and distal colon. In group 1, a lower frequency of recurrence was recorded 1 year following surgery when compared with group 2. Conclusion: Although recurrence are most likely, segmental resection improves the quality of life by delaying the need for a stoma and by preserving functioning bowel.
背景:关于节段性切除治疗克罗恩病存在争议。据报道,与全结肠切除术相比,节段性切除术与更高的再切除术率相关。这一主题在研究中很少涉及,术后功能结果也从未被记录。目的:本研究比较节段性结肠切除术和全结肠吻合术对切除、术后症状和肛肠功能的影响。材料和方法:本回顾性比较研究于2019年7月至2022年7月在白沙瓦哈亚塔巴德综合医院普外科进行。总共有70例局限于结肠或直肠的克罗恩病患者接受了手术切除。患者被分为三类之一:(a)节段性疾病,(b)保留直肠的全结肠炎,或(c)直肠炎。通过结肠镜检查、钡灌肠、上消化道系列检查及小肠随访、再手术时肠道大体检查或组织病理检查确定复发。结果:共纳入70例患者。年龄18-65岁,平均41.5岁。男性40例(57.1%),女性30例(42.9%),男女比例为1.3:1。最常见的症状是疼痛、腹泻和肛门直肠不适。50例(71.4%)患者通过结肠镜/内窥镜检查进行初步诊断,20例(28.6%)患者通过影像学检查进行初步诊断。将患者平均分为2组,即1组和2组(每组35例)。组1为全腹结肠切除术患者,组2为节段性切除术患者。两组肿瘤发生部位相似,均为结肠近端和结肠远端。与组2相比,组1术后1年的复发率较低。结论:虽然复发的可能性很大,但节段性切除通过延迟造口的需要和保留肠道功能来提高生活质量。
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引用次数: 0
Thrombofilias and the Risk of Recurring Pregnancy Loss in a Mexican Population 血栓形成和墨西哥人群中反复妊娠丢失的风险
Pub Date : 1900-01-01 DOI: 10.23880/mjccs-16000269
Vargas Hernández Víctor Manuel
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引用次数: 1
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Medical Journal of Clinical Trials & Case Studies
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