Pub Date : 2022-09-07DOI: 10.4274/gulhane.galenos.2022.41033
H. Ateş, E. Şahiner
Aims: We evaluated the knowledge, attitudes, and behaviors of residents and specialists working in tertiary healthcare institutions about drug allergy. Methods: Residents and specialist medical doctors working at a tertiary health institution were included in the study. A questionnaire consisting of questions evaluating occupational and demographic characteristics, knowledge, attitudes, and behaviors about drug allergy was prepared and administered to the participants. Result: Only 26 (21.3%) of the participants had attended any training on drug allergies. Of the participants, 73 (59.8%) felt competent in taking and interpreting an accurate allergy history for drugs. Of the participants, 107 (87.7%) knew that it is often impossible to reach a definite conclusion about drug allergy based on anamnesis alone. Only half of the participants stated that they could spare enough time for detailed anamnesis about drug allergy in their daily practice. Only 19 (15.6%) of the participants stated that they referred patients with suspected drug allergies to an allergist at a rate of 90-100%. When the answers of the assistant and specialists were compared;the proportion of respondents to the question of the most important drug classes responsible for allergic reactions, including antibiotics and aspirin/other NSAIDs (28.9% vs. 67.7%;p<.001). And the rate of those who responded corticosteroids+antihistamines+adrenaline to the question of the most recommended drug classes to treat drug allergies was found to be higher in specialist physicians (19.8% vs. 71%;p<.001). Conclusion: This cross-sectional study showed a low level of awareness, knowledge, and competency in the management of drug allergies among residents and specialists from different fields.
{"title":"Knowledge, attitudes, and behaviors of residents and specialists working in tertiary healthcare institutions about drug allergy","authors":"H. Ateş, E. Şahiner","doi":"10.4274/gulhane.galenos.2022.41033","DOIUrl":"https://doi.org/10.4274/gulhane.galenos.2022.41033","url":null,"abstract":"Aims: We evaluated the knowledge, attitudes, and behaviors of residents and specialists working in tertiary healthcare institutions about drug allergy. Methods: Residents and specialist medical doctors working at a tertiary health institution were included in the study. A questionnaire consisting of questions evaluating occupational and demographic characteristics, knowledge, attitudes, and behaviors about drug allergy was prepared and administered to the participants. Result: Only 26 (21.3%) of the participants had attended any training on drug allergies. Of the participants, 73 (59.8%) felt competent in taking and interpreting an accurate allergy history for drugs. Of the participants, 107 (87.7%) knew that it is often impossible to reach a definite conclusion about drug allergy based on anamnesis alone. Only half of the participants stated that they could spare enough time for detailed anamnesis about drug allergy in their daily practice. Only 19 (15.6%) of the participants stated that they referred patients with suspected drug allergies to an allergist at a rate of 90-100%. When the answers of the assistant and specialists were compared;the proportion of respondents to the question of the most important drug classes responsible for allergic reactions, including antibiotics and aspirin/other NSAIDs (28.9% vs. 67.7%;p<.001). And the rate of those who responded corticosteroids+antihistamines+adrenaline to the question of the most recommended drug classes to treat drug allergies was found to be higher in specialist physicians (19.8% vs. 71%;p<.001). Conclusion: This cross-sectional study showed a low level of awareness, knowledge, and competency in the management of drug allergies among residents and specialists from different fields.","PeriodicalId":35658,"journal":{"name":"Gulhane Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41497127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-23DOI: 10.4274/gulhane.galenos.2021.00719
Elif Aybala Oktay, S. Karaoğlanoğlu, N. Aydın, Akın Alper, B. Ersöz
{"title":"Geographical prevalence of dens invaginatus in the upper lateral teeth of young adult Turkish men","authors":"Elif Aybala Oktay, S. Karaoğlanoğlu, N. Aydın, Akın Alper, B. Ersöz","doi":"10.4274/gulhane.galenos.2021.00719","DOIUrl":"https://doi.org/10.4274/gulhane.galenos.2021.00719","url":null,"abstract":"","PeriodicalId":35658,"journal":{"name":"Gulhane Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41420130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-23DOI: 10.4274/gulhane.galenos.2021.1461
Zehra Çiçek, K. Akillioglu, A. S. Ilhan
{"title":"Roles of angiotensin II, Olmesartan and PD123319 on proliferation, oxidative stress and TGF-β1 in HUVEC culture","authors":"Zehra Çiçek, K. Akillioglu, A. S. Ilhan","doi":"10.4274/gulhane.galenos.2021.1461","DOIUrl":"https://doi.org/10.4274/gulhane.galenos.2021.1461","url":null,"abstract":"","PeriodicalId":35658,"journal":{"name":"Gulhane Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42134341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-23DOI: 10.4274/gulhane.galenos.2021.1531
Deepthi Shetty, A. Desai, N. Kumar, Dinesh U.S., A. Agnihotri, S. Bhaduri
{"title":"Multiple rare neoplasms arising from the nevus sebaceous of the scalp: A case report","authors":"Deepthi Shetty, A. Desai, N. Kumar, Dinesh U.S., A. Agnihotri, S. Bhaduri","doi":"10.4274/gulhane.galenos.2021.1531","DOIUrl":"https://doi.org/10.4274/gulhane.galenos.2021.1531","url":null,"abstract":"","PeriodicalId":35658,"journal":{"name":"Gulhane Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46719969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-23DOI: 10.4274/gulhane.galenos.2021.83703
Addisu Assefa Tadesse, Yeshumnesh Belete Gebrewold, H. Kloos
{"title":"Factors associated with treatment outcome of tuberculosis in Bale Robe General Hospital, Southeastern Ethiopia: A retrospective study","authors":"Addisu Assefa Tadesse, Yeshumnesh Belete Gebrewold, H. Kloos","doi":"10.4274/gulhane.galenos.2021.83703","DOIUrl":"https://doi.org/10.4274/gulhane.galenos.2021.83703","url":null,"abstract":"","PeriodicalId":35658,"journal":{"name":"Gulhane Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47764112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-23DOI: 10.4274/gulhane.galenos.2021.07379
Elzem Bolkan Günaydın, Mustafa Çağrı Öcalan, Aslıhan Uzunkulaoğlu, S. Ay
Aims: The study aimed to evaluate the association between the novel Coronavirus disease-2019 (COVID-19) pandemic and the level of pain, stress, sleep quality, and quality of life in patients with chronic musculoskeletal pain. Methods: This cross-sectional study included patients aged 18-65 years with chronic musculoskeletal pain. Age, gender, body mass index, systemic diseases, dominant pain area, duration of pain, analgesic use, and exercise habit before and after the pandemic were recorded. Participants were asked to evaluate their pain severity and global assessments in the last month and the pre-pandemic period with a visual analog scale (VAS). The Perceived Stress Scale (PSS), The Pittsburgh Sleep Quality Index (PSQI), and The Nottingham Health Profile (NHP) were administered Results: The study included 100 participants (age, mean ± SD: 42.8±12.5 years, female: 69%). Compared with the pre-pandemic period, an increase in pain and global assessment scores, and poorer sleep hygiene in the last month were reported by 82%, 67%, and 66%, respectively. Pain severity VAS score (pre-pandemic: 3.9±2 vs. post-pandemic: 5.9±2.1, p<0.001), global assessment VAS score (pre-pandemic: 3.8±2 vs. post-pandemic: 5.6±2.3, p<0.001), the proportion of patients using routine analgesics (pre-pandemic: 44% vs. post-pandemic: 52%, p=0.008), and the number of routine analgesics (pre-pandemic: 10.4±18.6 vs. post-pandemic: 15.3±24, p<0.001) in the last month was significantly more compared to the pre-pandemic period. There were no significant differences in pain score, patient’s global assessment score, the number of routine analgesics, PSS-14, PSQI, NHP-1, and NHP-2 scores between subjects with and without a history of COVID-19. Conclusions: In patients with chronic musculoskeletal pain, an increase in pain severity, analgesic use, and deterioration in general well-being were observed during the COVID-19 pandemic. The pronounced changes were not found to be dependent on the history of COVID-19. [ FROM AUTHOR] Copyright of Gulhane Medical Journal is the property of Gulhane Military Medical Academy and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)
目的：该研究旨在评估新型冠状病毒疾病2019（新冠肺炎）大流行与慢性肌肉骨骼疼痛患者的疼痛、压力、睡眠质量和生活质量之间的关系。方法：这项横断面研究包括18-65岁的慢性肌肉骨骼疼痛患者。记录大流行前后的年龄、性别、体重指数、全身性疾病、主要疼痛区域、疼痛持续时间、镇痛药的使用和锻炼习惯。参与者被要求用视觉模拟量表（VAS）评估他们在上个月和疫情前的疼痛严重程度和全球评估。采用感知压力量表（PSS）、匹兹堡睡眠质量指数（PSQI）和诺丁汉健康档案（NHP）。结果：该研究包括100名参与者（年龄，平均值±标准差：42.8±12.5岁，女性：69%）。与疫情前相比，上个月疼痛和全球评估得分增加，睡眠卫生状况较差，分别报告了82%、67%和66%。疼痛严重程度VAS评分（大流行前：3.9±2 vs.大流行后：5.9±2.1，p＜0.001），全球评估VAS评分（疫情前：3.8±2 vs.:大流行后：5.6±2.3，p＜001），使用常规镇痛药的患者比例（疫情前∶44%vs.疫后：52%，p＝0.008），上个月的常规镇痛药数量（大流行前：10.4±18.6 vs.大流行后：15.3±24，p＜0.001）明显多于大流行前。有和无新冠肺炎病史的受试者在疼痛评分、患者总体评估评分、常规止痛药数量、PSS-14、PSQI、NHP-1和NHP-2评分方面无显著差异。结论：在慢性肌肉骨骼疼痛患者中，在新冠肺炎大流行期间，观察到疼痛严重程度、镇痛药使用和总体健康状况恶化。没有发现明显的变化与新冠肺炎的病史有关。[发件人]《Gulhane Medical Journal》的版权归Gulhane军事医学院所有，未经版权持有人的明确书面许可，不得将其内容复制或通过电子邮件发送到多个网站或发布到listserv。但是，用户可以打印、下载或通过电子邮件发送文章供个人使用。这可能会被删节。对复印件的准确性不作任何保证。用户应参考材料的原始发布版本以获取完整信息。（版权适用于所有人。）
{"title":"Evaluation of the effects of the COVID-19 pandemic on pain, stress, sleep and quality of life in patients with chronic musculoskeletal pain","authors":"Elzem Bolkan Günaydın, Mustafa Çağrı Öcalan, Aslıhan Uzunkulaoğlu, S. Ay","doi":"10.4274/gulhane.galenos.2021.07379","DOIUrl":"https://doi.org/10.4274/gulhane.galenos.2021.07379","url":null,"abstract":"Aims: The study aimed to evaluate the association between the novel Coronavirus disease-2019 (COVID-19) pandemic and the level of pain, stress, sleep quality, and quality of life in patients with chronic musculoskeletal pain. Methods: This cross-sectional study included patients aged 18-65 years with chronic musculoskeletal pain. Age, gender, body mass index, systemic diseases, dominant pain area, duration of pain, analgesic use, and exercise habit before and after the pandemic were recorded. Participants were asked to evaluate their pain severity and global assessments in the last month and the pre-pandemic period with a visual analog scale (VAS). The Perceived Stress Scale (PSS), The Pittsburgh Sleep Quality Index (PSQI), and The Nottingham Health Profile (NHP) were administered Results: The study included 100 participants (age, mean ± SD: 42.8±12.5 years, female: 69%). Compared with the pre-pandemic period, an increase in pain and global assessment scores, and poorer sleep hygiene in the last month were reported by 82%, 67%, and 66%, respectively. Pain severity VAS score (pre-pandemic: 3.9±2 vs. post-pandemic: 5.9±2.1, p<0.001), global assessment VAS score (pre-pandemic: 3.8±2 vs. post-pandemic: 5.6±2.3, p<0.001), the proportion of patients using routine analgesics (pre-pandemic: 44% vs. post-pandemic: 52%, p=0.008), and the number of routine analgesics (pre-pandemic: 10.4±18.6 vs. post-pandemic: 15.3±24, p<0.001) in the last month was significantly more compared to the pre-pandemic period. There were no significant differences in pain score, patient’s global assessment score, the number of routine analgesics, PSS-14, PSQI, NHP-1, and NHP-2 scores between subjects with and without a history of COVID-19. Conclusions: In patients with chronic musculoskeletal pain, an increase in pain severity, analgesic use, and deterioration in general well-being were observed during the COVID-19 pandemic. The pronounced changes were not found to be dependent on the history of COVID-19. [ FROM AUTHOR] Copyright of Gulhane Medical Journal is the property of Gulhane Military Medical Academy and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)","PeriodicalId":35658,"journal":{"name":"Gulhane Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47898373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-23DOI: 10.4274/gulhane.galenos.2021.46036
G. Kaner, N. Inanc, E. Başmısırlı, K. Ünlühızarcı
{"title":"Evaluation of 25-hydroxyvitamin D levels in obese individuals","authors":"G. Kaner, N. Inanc, E. Başmısırlı, K. Ünlühızarcı","doi":"10.4274/gulhane.galenos.2021.46036","DOIUrl":"https://doi.org/10.4274/gulhane.galenos.2021.46036","url":null,"abstract":"","PeriodicalId":35658,"journal":{"name":"Gulhane Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45732156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-23DOI: 10.4274/gulhane.galenos.2021.80299
Tuğba Küçükkasap Cömert, D. Ağagündüz, Özlem Muşlu, A. Güçlü, Hulya Zengin, Bediye Öztaş, S. Akarsu
{"title":"Low serum zinc and total antioxidant capacity levels in individuals with premenstrual syndrome","authors":"Tuğba Küçükkasap Cömert, D. Ağagündüz, Özlem Muşlu, A. Güçlü, Hulya Zengin, Bediye Öztaş, S. Akarsu","doi":"10.4274/gulhane.galenos.2021.80299","DOIUrl":"https://doi.org/10.4274/gulhane.galenos.2021.80299","url":null,"abstract":"","PeriodicalId":35658,"journal":{"name":"Gulhane Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46782145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-23DOI: 10.4274/gulhane.galenos.2021.73745
Özlem Akgün Doğan, N. Ağaoğlu
{"title":"Clinical findings and molecular diagnosis in children with Bardet-Biedl Syndrome in Turkey: Identification of novel variants","authors":"Özlem Akgün Doğan, N. Ağaoğlu","doi":"10.4274/gulhane.galenos.2021.73745","DOIUrl":"https://doi.org/10.4274/gulhane.galenos.2021.73745","url":null,"abstract":"","PeriodicalId":35658,"journal":{"name":"Gulhane Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44105922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-23DOI: 10.4274/gulhane.galenos.2021.02996
Ayberk Selek, Melike Arslan, O. Gürsel, N. Balamtekin
{"title":"Treatment of pediatric patients with Down syndrome, acute lymphoblastic leukemia, and hepatitis C infection by direct-acting antivirals","authors":"Ayberk Selek, Melike Arslan, O. Gürsel, N. Balamtekin","doi":"10.4274/gulhane.galenos.2021.02996","DOIUrl":"https://doi.org/10.4274/gulhane.galenos.2021.02996","url":null,"abstract":"","PeriodicalId":35658,"journal":{"name":"Gulhane Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47899447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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