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Implantation Technique for the Aeson Total Artificial Heart Aeson 全人工心脏的植入技术
Q3 Medicine Pub Date : 2024-06-01 DOI: 10.1053/j.optechstcvs.2024.01.002
André Vincentelli MD, PhD , Yuriy Pya MD , Ivan Netuka MD, PhD , Assad Haneya MD, PhD , Jan Schmitto MD, PhD , Michel Kindo MD, PhD , Peter Wearden MD, PhD , Piet Jansen MD, PhD , Christian Latremouille MD, PhD

The autoregulated, pulsatile Aeson total artificial heart (Carmat SA, Vélizy, France) is a single-unit biventricular device. The central body comprises the 2 blood pumping ventricles and separate technical compartments which house 2 electrohydraulic pumps and control electronics which employ an algorithm informed by pressure sensors and volume detection transducers in each ventricle. The prosthesis is connected by an 8 mm driveline, which exits the skin in the lower right quadrant, to an external routing module and a controller powered by batteries. Since the first implantation took place in 2013, more than 50 patients have been successfully implanted during clinical studies, and commercially after the Aeson obtained its CE mark in 2020, as a bridge to transplant device. The size of the device and the lack of adhesions around the device body have been shown to facilitate relatively easy explanation and subsequent transplantation.

With the growing experience, the implant procedure has evolved from experimental to a well-established routine procedure. The purpose of this article is to provide a guide for potential implanters in order to ensure that the advanced design benefits of the Aeson TAH are realized by incorporating optimal surgical techniques.

自动调节、搏动式 Aeson 全人工心脏(Carmat SA,法国韦利齐)是一种单体双心室装置。中央主体由两个泵血心室和独立的技术舱组成,技术舱内装有两个电液泵和控制电子装置,控制电子装置采用的算法由每个心室中的压力传感器和容积检测传感器提供信息。假体通过一条从右下象限皮肤穿出的 8 毫米动力线与外部路由模块和由电池供电的控制器相连。自 2013 年首次植入以来,已有 50 多名患者在临床研究中成功植入了假体,2020 年 Aeson 获得 CE 标志后,该假体作为移植手术的桥梁设备投入商业使用。该装置的尺寸和装置体周围无粘连的特点已被证明有利于相对简便的解释和后续移植。随着经验的不断积累,植入程序已从实验性程序发展为成熟的常规程序。本文旨在为潜在的植入者提供指导,以确保通过采用最佳手术技术实现 Aeson TAH 先进的设计优势。
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引用次数: 0
Minimally Invasive Complex Segmentectomies of the Right Upper Lobe: Anterior Segmentectomy, Apical Segmentectomy, and Posterior Segmentectomy 右上叶复杂节段的微创切除术:前节段切除术、根尖节段切除术和后节段切除术
Q3 Medicine Pub Date : 2024-03-01 DOI: 10.1053/j.optechstcvs.2023.06.002
Eserval Rocha Júnior MD , Ricardo Mingarini Terra MD, PhD

Anatomic segmentectomy becomes an actual therapeutic option for the thoracic surgeon on lung cancer treatment. Mostly applied for early-stage lung cancer resections, its applications go further passing from localized benign disease and metastatic lung lesions. Due to the anatomic complexity and the vascular anatomic variations of the segments, It is usually more technically challenging than a standard lobectomy. This complexity is noted mainly in single-segment resections where there is a need to treat more than 1 intersegmental plane. The great anatomical variation and the high occurrence of lesions in the upper lobes make it important to study sublobar resections of the right upper lobe. Performing it with minimally invasive access requires a great knowledge of the technique to standardize the approach avoid pitfalls and optimize the procedure outcomes. This paper aims to describe the anatomic segmental resections of the right upper lobe performed by minimally invasive access, anticipating instructions for video thoracoscopic and robotic approaches.

解剖分段切除术已成为胸外科医生治疗肺癌的实际选择。该手术主要用于早期肺癌切除,其应用范围进一步扩展到局部良性疾病和转移性肺部病变。由于解剖的复杂性和肺段血管解剖的变化,它通常比标准的肺叶切除术更具技术挑战性。这种复杂性主要体现在需要处理一个以上肺段间平面的单肺段切除术中。上叶的解剖结构变化大,病变发生率高,因此研究右上叶的叶下切除术非常重要。采用微创入路进行该手术需要大量的技术知识,以规范手术方法,避免误区,优化手术效果。本文旨在描述通过微创入路进行的右上叶解剖分段切除术,并对视频胸腔镜和机器人方法进行了预测说明。
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引用次数: 0
Norwood-Sano Procedure With Neo-aortic Valve Repair on the Beating Heart 诺伍德-萨诺手术,在跳动的心脏上进行新主动脉瓣修复术
Q3 Medicine Pub Date : 2024-03-01 DOI: 10.1053/j.optechstcvs.2023.11.002
Igor E. Konstantinov MD, PhD, FRACS , Edward Buratto MBBS, PhD, FRACS , Shuta Ishigami MD, PhD , Bosco Moscoso MD

Norwood operation for patients with hypoplastic left heart syndrome or its variants may be associated with prolonged period of myocardial ischemia, particularly in those, who may require associated neo-aortic valve repair. Using the myocardial perfusion technique described herein, the heart could remain beating in normal sinus rhythm during the entire procedure, including neo-aortic valve repair and root reconstruction, and the need for cardioplegic heart arrest can be eliminated.

对左心发育不全综合征或其变异型患者进行诺伍德手术可能会导致长时间的心肌缺血,尤其是那些可能需要进行新主动脉瓣修复的患者。使用本文所述的心肌灌注技术,心脏可在整个手术过程中保持正常窦性心律跳动,包括新主动脉瓣修复和根部重建,而且无需进行心脏停搏。
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引用次数: 0
How I Do the Norwood Operation 我如何进行诺伍德操作
Q3 Medicine Pub Date : 2024-03-01 DOI: 10.1053/j.optechstcvs.2023.09.007
Douglas M. Overbey MD, MPH , Nicholas D. Andersen MD , Joseph W. Turek MD, PhD, MBA

The Norwood procedure can be performed with several variations including a sustained total all-region (STAR) perfusion technique, introduced at our institution 5 years ago and well described in a prior Operative Techniques article. Regardless of technique heterogeneity, national outcomes continue to demonstrate that the Norwood procedure carries one of the highest mortalities of all congenital heart operations. Our technique of STAR perfusion provides total body perfusion during the entire Norwood reconstruction, avoiding coagulopathy associated with significant cooling and ischemic time to end-organs. Over the past few years, we have refined the technique, and describe key variations and modifications in this article.

诺伍德手术可以通过多种方法进行,包括持续全区域(STAR)灌注技术,该技术于 5 年前在我院引入,并在之前的一篇《手术技术》文章中进行了详细描述。无论采用哪种技术,全国性的结果都表明,诺伍德手术是所有先天性心脏病手术中死亡率最高的手术之一。我们的 STAR 灌注技术可在整个诺伍德重建过程中提供全身灌注,避免了因末端器官显著冷却和缺血时间而引起的凝血病变。在过去的几年中,我们对该技术进行了改进,并在本文中介绍了主要的变化和修改。
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引用次数: 0
A Novel Approach for Simultaneous Venoarterial Extracorporeal Membrane Oxygenation and Left Ventricular Decompression Therapy With Impella (ECPella) 体外膜肺氧合与左心室减压疗法(ECPella)同时进行的新方法
Q3 Medicine Pub Date : 2024-03-01 DOI: 10.1053/j.optechstcvs.2023.11.004
Breah Paciotti MPH, PA-C , Pankaj Garg MBBS , James Postier , Amy Lykins APRN, DNP , Basar Sareyyupoglu MD

Percutaneously placed veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is commonly used to support patients with refractory cardiac arrhythmias or arrest and worsening cardiogenic shock. Peripheral VA-ECMO by retrograde flow of blood in the aorta results in a significant increase in left ventricle (LV) afterload. A severely dysfunctional LV may be unable to overcome this afterload to open the aortic valve and unload itself. This may lead to LV distension, increased LV pressure, poor coronary blood circulation, increased left atrial pressures, pulmonary edema, and pulmonary hypertension. Moreover, it jeopardizes ventricular recovery, particularly in the presence of ischemia-induced myocardial impairment. Furthermore, if the aortic valve remains closed during the cardiac cycle, stasis of blood in the LV and aortic root may increase the risk of thrombus formation. These complications may preclude cardiac recovery and the patient from being a heart transplant candidate. In patients with cardiogenic shock, utilizing Impella with VA-ECMO, commonly referred to as ECPella, has consistently been shown to reduce mortality and improve outcomes. Patients who need prolonged ECPella support as a bridge to recovery or transplant may remain bed-bound since ambulation of patients with 2 mechanical circulatory support devices is challenging. We present the technique of ECPella placement through Y chimney graft anastomosis on the axillary artery for arterial cannula and Impella insertion and percutaneous cannulation of the right internal Jugular vein for venous cannula. This technique gives the ease of ambulation and decannulation of VA-ECMO under local anesthesia without requiring intubation or a trip to the operating room.

经皮置入静脉-动脉体外膜肺氧合(VA-ECMO)常用于支持难治性心律失常或心跳骤停以及心源性休克恶化的患者。通过主动脉血液逆流进行外周体外膜肺氧合(VA-ECMO)会导致左心室(LV)后负荷显著增加。严重功能障碍的左心室可能无法克服这种后负荷来打开主动脉瓣并自行卸载。这可能导致左心室膨胀、左心室压力增加、冠状动脉血液循环不良、左心房压力增加、肺水肿和肺动脉高压。此外,这还会危及心室的恢复,尤其是在缺血导致心肌受损的情况下。此外,如果主动脉瓣在心动周期中一直处于关闭状态,左心室和主动脉根部的血液淤积可能会增加血栓形成的风险。这些并发症可能导致心脏功能无法恢复,患者也无法成为心脏移植的候选者。在心源性休克患者中,利用 Impella 与 VA-ECMO(通常称为 ECPella)可持续降低死亡率并改善预后。需要长期 ECPella 支持作为康复或移植桥梁的患者可能仍需卧床,因为使用 2 个机械循环支持装置的患者的行动具有挑战性。我们介绍了通过腋动脉 Y 型烟囱移植吻合术放置 ECPella 的技术,用于动脉插管和 Impella 插入,以及经皮插入右颈内静脉用于静脉插管。这种技术使 VA-ECMO 在局部麻醉的情况下就能方便地行走和拔管,而无需插管或前往手术室。
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引用次数: 0
Introduction to Spring 2024 2024 年春季介绍
Q3 Medicine Pub Date : 2024-03-01 DOI: 10.1053/j.optechstcvs.2024.03.001
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引用次数: 0
Valved Conduit for Norwood-Sano Procedure 用于诺伍德-萨诺程序的阀式导管
Q3 Medicine Pub Date : 2024-03-01 DOI: 10.1053/j.optechstcvs.2023.09.005
David Kalfa MD, PhD, Edward Buratto MD, PhD, Andrew Goldstone MD, PhD, Emile Bacha MD

Use of a valved Sano (VS) during the Norwood procedure has been reported previously, but is not widely used and its impact on clinical outcomes needs to be further elucidated. Our institution shifted practice to the VS operation entirely in 2019, using a valved femoral venous homograft. We describe our technique in the present report. The VS technique is well codified and highly reproducible. Pre-Glenn echocardiograms showed competent conduit valves in two-thirds of the VS patients (n = 16/25, 66.7%). We retrospectively reviewed 25 consecutive HLHS neonates who underwent a Norwood procedure with a VS conduit using a femoral venous homograft and 25 consecutive HLHS neonates who underwent a Norwood procedure with a non-valved Sano (NVS) conduit between 2013 and 2022. Hospital survival for the VS group was 96%. Postoperatively, VS patients had significantly lower peak and postoperative day 1 lactate levels (p = 0.033 and p = 0.025 respectively), shorter time to diuresis (p = 0.043), and shorter time to enteral feeds (p = 0.038). The VS group had significantly fewer PA reinterventions until the Glenn (n = 1 vs 8; p = 0.044). The VS group showed significant improvement in ventricular function from the immediate postoperative period to discharge (p < 0.001). From preoperative to pre-Glenn time points, analysis of ventricular function showed sustained ventricular function within the VS group, but a significant reduction of ventricular function in the NVS group (p = 0.003). The use of a valved conduit for Norwood-Sano procedure is a reproducible technique, associated with improved multi-organ recovery, ventricular function recovery and fewer PA reinterventions.

诺伍德手术中使用瓣膜化萨诺(VS)的情况此前已有报道,但并未广泛使用,其对临床结果的影响也有待进一步阐明。我院于 2019 年完全转向 VS 手术,使用带瓣股静脉同源移植物。我们在本报告中介绍了我们的技术。VS 技术经过精心编纂,具有很高的可重复性。格伦前超声心动图显示,三分之二的 VS 患者(n = 16/25,66.7%)导管瓣膜功能正常。我们回顾性分析了2013年至2022年间连续接受诺伍德手术、使用股静脉同源移植VS导管的25例HLHS新生儿,以及连续接受诺伍德手术、使用无瓣萨诺(NVS)导管的25例HLHS新生儿。VS组的住院存活率为96%。术后,VS 组患者的乳酸水平峰值和术后第 1 天乳酸水平明显降低(分别为 p = 0.033 和 p = 0.025),利尿时间缩短(p = 0.043),肠内喂养时间缩短(p = 0.038)。在格伦之前,VS 组再次进行 PA 干预的次数明显减少(n = 1 vs 8;p = 0.044)。从术后到出院,VS 组的心室功能明显改善(p < 0.001)。从术前到格伦前的时间点,对心室功能的分析表明,VS 组的心室功能保持稳定,但 NVS 组的心室功能明显下降(p = 0.003)。在诺伍德-萨诺手术中使用瓣膜导管是一种可重复的技术,可改善多器官恢复、心室功能恢复和减少 PA 再干预。
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引用次数: 0
Commentary: I'd love to agree with you, but then we would both be wrong 评论:我很想同意你的观点,但那样我们就都错了
Q3 Medicine Pub Date : 2024-03-01 DOI: 10.1053/j.optechstcvs.2023.12.004
Ronald K. Woods MD, PhD
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引用次数: 0
Commentary: The Expanding Norwood Tool Kit—You Decide 评论:不断扩大的诺伍德工具包--由您决定
Q3 Medicine Pub Date : 2024-03-01 DOI: 10.1053/j.optechstcvs.2023.09.006
Tracy R. Geoffrion MD, MPH, Ronald K. Woods MD, PhD
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引用次数: 0
Commentary: Right Upper Lobe Segmentectomies : A Game of Details 评论:右上叶段切除术:细节的游戏。
Q3 Medicine Pub Date : 2024-03-01 DOI: 10.1053/j.optechstcvs.2023.11.003
George Rakovich MD, MA(Ed)
{"title":"Commentary: Right Upper Lobe Segmentectomies : A Game of Details","authors":"George Rakovich MD, MA(Ed)","doi":"10.1053/j.optechstcvs.2023.11.003","DOIUrl":"10.1053/j.optechstcvs.2023.11.003","url":null,"abstract":"","PeriodicalId":35965,"journal":{"name":"Operative Techniques in Thoracic and Cardiovascular Surgery","volume":"29 1","pages":"Pages 129-131"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138610669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Operative Techniques in Thoracic and Cardiovascular Surgery
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