Moisture condensation inside packages is one frequent problem when packaging fresh stuff such as vegetables. This process leads to microbial deterioration, loss of nutrients, increased enzymatic degradation, and shelf-life reduction. In this study, cellulose and carboxymethylcellulose (CMC) based aerogels were developed as an environmentally -friendly alternative to minimize condensation. Initially, aqueous dispersions between 1 and 5 % (w/w) were prepared for each material. CaCO3 and CaCl2 were evaluated as chemical cross-linkers (5 % w/w). Aerogels were obtained starting with high-speed dispersion (15500 rpm), followed by ultra-cooling (−45 °C for 24 h) and finally freeze-drying (−75 °C for 24 h). The aerogels were characterized by measuring different thermophysical properties. The aerogel with the highest moisture adsorption capacity (Cads) obtained was that of cellulose + CaCl2 (5 % each in aqueous dispersion) with an equilibrium water vapor adsorption (Cads) of 0.58 g g−1 at 20 °C and 60 % RH. The moisture adsorption on that aerogel was modeled by fitting a combined pseudo-first-order kinetics and an adsorption equilibrium equation (GAB) obtaining an adjusted R2 of 0.864. The aerogel performance was experimentally evaluated by packaging freshly cut melon (95 g) together with 3–6 g of aerogel blocks in perforated polyethylene terephthalate (PET) trays at 8 °C and 80 % RH. A shelf life of 8 days was achieved for the cut fruits compared to 3 days for samples in open trays and 5 days for fruits in closed trays without aerogel. The cellulose-based aerogels can be a suitable and sustainable alternative for sustainably preserving fresh products in active packaging.