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Ruptured intracranial dermoid: Case report and literature review 颅内皮样破裂病例报告及文献复习
Q4 Medicine Pub Date : 2017-05-01 DOI: 10.4103/0975-2870.206576
P. Survashe, S. Guthe, V. Velho, A. Bhide
Intracranial dermoid cysts are nonneoplastic, ectodermal inclusion cysts of embryological origin. They contain various ectodermal derivatives including apocrine glands, sebaceous glands, hairs, squamous epithelium, and occasionally teeth. Spontaneous rupture of these cysts is uncommon, and so far very few cases have been reported in the literature. Hereby, we report a case of young male presenting with ruptured intracranial dermoid cyst managed surgically.
颅内皮样囊肿是胚胎起源的非肿瘤性外胚层包涵性囊肿。它们含有各种外胚层衍生物,包括大汗腺、皮脂腺、毛发、鳞状上皮,偶尔还有牙齿。这些囊肿的自发破裂是不常见的,到目前为止,文献报道的病例很少。在此,我们报告一例年轻男性表现为颅内皮样囊肿破裂手术处理。
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引用次数: 1
A case report of emergency cesarean section in parturient with kyphoscoliosis 后凸畸形产妇紧急剖宫产1例报告
Q4 Medicine Pub Date : 2017-05-01 DOI: 10.4103/0975-2870.206573
Raghavendra Vagyannavar, R. Devi
Anesthesia for emergency cesarean section for the pregnancy with kyphoscoliosis is associated with potential risks for both mother and fetus due to alterations in maternal physiology and the pathological changes seen in kyphoscoliosis. The anesthetic management must include the well-being of both mother and fetus. The need of anesthesia for delivery in pregnant women with kyphoscoliosis is more than the normal parturient. We report the case of a 23-year-old female, full-term primigravida with kyphoscoliosis who was posted for emergency caesarean section. The anesthetic management of this patient is presented here.
由于母体生理学的改变和后凸畸形的病理变化,妊娠期后凸畸形紧急剖宫产的麻醉对母亲和胎儿都有潜在的风险。麻醉管理必须包括母亲和胎儿的健康。患有后凸畸形的孕妇分娩时需要麻醉的次数比正常产妇多。我们报告了一例23岁的女性,患有后凸畸形的足月初产妇,被安排进行紧急剖腹产。这个病人的麻醉管理在这里介绍。
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引用次数: 0
The accuracy of polyuria, polydipsia, polyphagia, and Indian Diabetes Risk Score in adults screened for diabetes mellitus type-II 成人II型糖尿病筛查中多尿、多饮、多食和印度糖尿病风险评分的准确性
Q4 Medicine Pub Date : 2017-05-01 DOI: 10.4103/0975-2870.206569
S. Pawar, Poonam Thakur, B. Radhe, H. Jadhav, Vivek Behere, Vikrant Pagar
Context: The World Health Organization report suggests that over 19% of the world's diabetic population currently resides in India. Unfortunately, >50% of the diabetics in India are unaware about their diabetic status. In the poor income country like India, it is essential to use cost-effective methods for screening for diabetes, and traditionally using three classical symptoms and Indian Diabetes Risk Score (IDRS) tool is helpful but, data regarding their diagnostic accuracy is very less. Objective: (1) To assess the diagnostic accuracy of polyuria, polydipsia, polyphagia, and IDRS for detecting diabetes. Settings and Design: Six hundred and seventy-seven adult individuals >20 years of age were screened for diabetes and assessed polyuria, polydipsia, polyphagia, and IDRS score. All were subjected for postprandial blood glucose level. Subjects and Methods: For diagnostic accuracy sensitivity, specificity, positive and negative predictive values, likelihood ratios (LRs, for positive and negative tests), and accuracy was calculated for each symptom. Similarly, by receiver operative curve (ROC) curve analysis, we carried out sensitivity and specificity of IDRS. Results: There was statistically significant association between these three classical symptoms and diabetes status of individuals. When present, all these three symptoms carried 7.34% sensitivity and 98.42% specificity with positive predictive value 47.06% and NPV 84.70%, LR+4.36, LR−0.94 with accuracy of 85%. The optimum cutoff value of IDRS score was >50, which carried sensitivity 73%, specificity 58.7%, and area under curve for ROC was 68% (P < 0.001). Conclusions: This study has shown highest specificity for these three classical symptoms in diagnosing diabetes, but these symptoms were insensitive to detect all diabetic subjects.
背景:世界卫生组织的报告表明,目前世界糖尿病人口的19%以上居住在印度。不幸的是,印度50%以上的糖尿病患者不知道自己的糖尿病状况。在印度这样的低收入国家,使用具有成本效益的方法筛查糖尿病至关重要,传统上使用三种经典症状和印度糖尿病风险评分(IDRS)工具是有帮助的,但有关其诊断准确性的数据非常少。目的:(1)评价多尿、多饮、多食和IDRS对糖尿病的诊断准确性。设置和设计:对677名>20岁的成年个体进行糖尿病筛查,并评估多尿、多饮、多食和IDRS评分。所有人都接受了餐后血糖水平测试。受试者和方法:计算每种症状的诊断准确性、敏感性、特异性、阳性和阴性预测值、似然比(阳性和阴性检测的LR)和准确性。同样,通过受试者操作曲线(ROC)曲线分析,我们进行了IDRS的敏感性和特异性。结果:这三种典型症状与个体的糖尿病状况之间存在统计学上显著的相关性。当存在时,所有这三种症状的敏感性为7.34%,特异性为98.42%,阳性预测值为47.06%,NPV为84.70%,LR+4.36,LR-0.94,准确率为85%。IDRS评分的最佳临界值>50,ROC的敏感性为73%,特异性为58.7%,曲线下面积为68%(P<0.001)。
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引用次数: 8
Evidence-based safety and efficacy of Ayurvedic herbo-metallic preparations containing gold, iron, and mercury with special reference to pediatrics 含金、铁和汞的阿育吠陀草药金属制剂对儿科的循证安全性和有效性
Q4 Medicine Pub Date : 2017-05-01 DOI: 10.4103/0975-2870.206579
Rahul K Shingadiya, Suhas A. Chaudhary, Krutika Joshi, P. Bedarkar, B. Patgiri, P. Prajapati
Background: Safety and efficacy of herbo- metallic or mineral formulations in Ayurvedic therapeutics is subject of great concern in present era. Especially in paediatrics in which, a number of herbo-metallic formulations are found in practice for prevention as well as for the treatment of paediatric disorders. Among various herbo-metallic preparations mentioned in Ayurveda, gold, iron and mercurial formulations are more popular in paediatric practices. Present study has been conducted to highlight an evidence based safety and efficacy of metallic preparations in paediatrics. Material and Method: Subject related published research articles from reputed journals were searched through four online search engines Pubmed, Google scholar and Ayush research portal and DHARA online. The data of the articles were analysed to confirm their safety and efficacy in paediatrics. Results: Total 10 clinical studies showing safety and efficacy of Ayurvedic herbo-metallic preparations in paediatric disorders were compiled, which included 3 formulations of gold, 4 of iron and 3 mercurial formulations. Children suffering from Chronic tonsillitis, Iron deficiency anaemia, Sickle cell anaemia and Bronchial asthma were treated with significant effect and positive changes in haematological parameters. No any adverse or toxic effect of any of these formulations was noticed. Conclusion: Metallic preparations of gold, iron and mercury are found quite safe to the use in pediatric disorders with proper dose and adjuvant. They are also found effective in the diseases which are chronic and diffi cult to treat such as sickle cell anemia, seizure, and acute lymphoblastic leukemia.
背景:草药金属或矿物制剂在阿育吠陀治疗中的安全性和有效性在当今时代备受关注。特别是在儿科,在实践中发现了许多草药金属制剂,用于预防和治疗儿科疾病。在阿育吠陀提到的各种草药金属制剂中,金、铁和汞制剂在儿科实践中更受欢迎。本研究旨在强调金属制剂在儿科的循证安全性和有效性。材料和方法:通过四个在线搜索引擎Pubmed、谷歌学者和阿尤什研究门户网站以及DHARA在线搜索知名期刊上发表的与主题相关的研究文章。对这些文章的数据进行了分析,以确认它们在儿科的安全性和有效性。结果:总共汇编了10项临床研究,显示阿育吠陀草药金属制剂治疗儿童疾病的安全性和有效性,其中包括3种金制剂、4种铁制剂和3种汞制剂。对患有慢性扁桃体炎、缺铁性贫血、镰状细胞贫血和支气管哮喘的儿童进行了治疗,效果显著,血液学参数发生了积极变化。未发现任何此类制剂有任何不良或毒性作用。结论:金、铁、汞等金属制剂在适当剂量和辅助条件下治疗小儿疾病是安全的。它们还被发现对慢性和难以治疗的疾病有效,如镰状细胞贫血、癫痫发作和急性淋巴细胞白血病。
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引用次数: 1
Value of transcutaneous electric nerve stimulation in the treatment of myofascial pain dysfunction syndrome 经皮神经电刺激治疗肌筋膜疼痛功能障碍综合征的价值
Q4 Medicine Pub Date : 2017-05-01 DOI: 10.4103/MJDRDYPU.MJDRDYPU_196_16
H. Handa, A. Deshpande, S. Punyani
Pain in facial region originating from both temporomandibular joint (TMJ) and jaw muscles is a common clinical problem and is a diagnostic dilemma till today. There are many synonyms for this condition including myofascial pain dysfunction syndrome, mandibular dysfunction syndrome, and the TMJ dysfunction syndrome. With change in time, advances and new diagnostic criteria have been made in the diagnosis of myofascial pain syndrome, its epidemiology, clinical characteristics, and etiopathogenesis, but many unknowns remain. An integrated hypothesis has provided a greater understanding of the physiopathology of trigger points, which may allow the development of new diagnostic criteria and treatment of this chronic disease and combined pharmacological as well as physical therapy for the management of the disease. The purpose of this paper is to describe the multidisciplinary approach highlighting the effect of transcutaneous electric nerve stimulation (TENS) for the treatment of a 60-year-old female who suffered from myofascial pain and 5-day TENS therapy for management of pain.
颞下颌关节和下颌肌肉引起的面部疼痛是一个常见的临床问题,至今仍是一个诊断难题。这种情况有很多同义词,包括肌筋膜疼痛功能障碍综合征、下颌功能障碍综合征和TMJ功能障碍综合征。随着时间的变化,在肌筋膜疼痛综合征的诊断、流行病学、临床特征和发病机制方面取得了进展,并提出了新的诊断标准,但仍有许多未知之处。一个综合的假设提供了对触发点的生理病理学的更好理解,这可能有助于开发新的诊断标准和治疗这种慢性疾病,并结合药物和物理治疗来管理这种疾病。本文的目的是描述多学科方法,强调经皮神经电刺激(TENS)治疗一名60岁女性肌筋膜疼痛的效果,以及为期5天的TENS治疗疼痛的效果。
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引用次数: 2
Pharmacists' knowledge and perceptions about herbal medicines: A case study of Jos and environs 药师对中草药的认识与认知:以乔斯市及周边地区为例
Q4 Medicine Pub Date : 2017-05-01 DOI: 10.4103/MJDRDYPU.MJDRDYPU_298_16
N. Jimam, B. Joseph, Dooshima C Agba
Background: Due to increased health consciousness among the public, the use of herbal products are on the increase on a daily basis. To achieve optimal benefits, there is a need for pharmacists who are the custodians of knowledge on drugs and drugs-related products to have more understanding and interest in herbal medicine for effective counseling on the products. The purpose of this study was to assess Pharmacists' knowledge and perceptions regarding herbal medicine use. Methods: Self-administered questionnaires were administered to 200 pharmacists working within the study areas to fill; after which the collected data were statistically analyzed using IBM SPSS software programmer, version 20. Results: Only 88.5% of the respondents responded on the questionnaires, and their mean age was 34 years; median year of experience in practice was 8.2 years; and their areas of practice included hospital (56.1%), community (28.1%), academic (8.47%), and industries (4.52%). More than half (76.27%) of them believed that herbal products were more efficacious and safer (61.02%) than orthodox medicines; with almost all of them (94.92%) acknowledging the beneficial effects of incorporating herbal medicines into orthodox medicine practice. However, most of them (72.88%) confessed having little knowledge on herbal remedies, especially drug-herbs interactions (81.36%), and their main source of information on herbs was from school (56.50%). Conclusions: The result showed poor level of pharmacists' knowledge on herbal medicine; which might result in poor patients' counseling on herbal therapy, especially regarding their safety and potential interaction with orthodox medicine.
背景:由于公众健康意识的增强,草药产品的使用每天都在增加。为了实现最佳效益,药剂师作为药物和药物相关产品知识的保管人,需要对草药有更多的了解和兴趣,以便对产品进行有效的咨询。本研究的目的是评估药剂师对草药使用的知识和看法。方法:对在研究区域内工作的200名药剂师进行自我管理问卷调查;之后使用IBM SPSS软件程序员版本20对收集的数据进行统计分析。结果:只有88.5%的受访者回答了问卷,他们的平均年龄为34岁;执业经验中位数为8.2年;他们的执业领域包括医院(56.1%)、社区(28.1%)、学术(8.47%)和工业(4.52%)。超过一半(76.27%)的人认为草药产品比传统药物更有效、更安全(61.02%);几乎所有人(94.92%)都承认将草药纳入传统医学实践的有益效果。但绝大多数(72.88%)承认对草药,尤其是药物与草药的相互作用知之甚少(81.36%),其草药信息的主要来源为学校(56.50%);这可能会导致患者对草药治疗的咨询较差,尤其是在其安全性和与传统药物的潜在相互作用方面。
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引用次数: 4
Uncommon associations of Hepatitis A in children: Acute respiratory distress syndrome and erosive gastritis 儿童甲型肝炎的罕见关联:急性呼吸窘迫综合征和糜烂性胃炎
Q4 Medicine Pub Date : 2017-05-01 DOI: 10.4103/0975-2870.206580
S. Parikh, I. Shah, S. Bhatnagar
Hepatitis A is a common cause of acute hepatitis in children and usually has a benign self-limiting course, moreover so in young children. We report two exceptional cases of erosive gastritis and acute respiratory distress syndrome, respectively, as rare associations of hepatitis A in children. Both children were <5 years of age and eventually recovered.
甲型肝炎是儿童急性肝炎的常见病因,通常有一个良性的自限性病程,而且在幼儿中也是如此。我们报告两个例外的情况下,糜烂性胃炎和急性呼吸窘迫综合征,分别为罕见的关联甲型肝炎在儿童。两名儿童均小于5岁,并最终康复。
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引用次数: 0
Prevalence of depression in mothers of intellectually disabled children: A cross-sectional study 智力残疾儿童母亲抑郁患病率的横断面研究
Q4 Medicine Pub Date : 2017-03-01 DOI: 10.4103/0975-2870.202103
Gourav Chandravanshi, K. Sharma, C. Jilowa, P. Meena, M. Jain, O. Prakash
Background: Intellectual disability (ID) is a permanent and highly disabling condition. The birth of a disabled child induces complex feelings in mother and other family members. This study was planned to investigate phenomenology of ID and the prevalence of depression in their mothers. Objective: To find prevalence, influence of various sociodemographic variables, and its clinical correlation with depression in mothers of ID children. Study Design: A cross-sectional study. Materials and Methods: A total of 100 patients diagnosed as ID were included in the study. Objective data were collected in a special Pro forma, and mothers of these patients were evaluated with the Beck's Anxiety Inventory and Beck's Depression Inventory. Results: The mean age of patients with ID was 11.52 years, had received an average of 3.01 years of schooling, mean age at diagnosis was 6.01 years, mean intelligence quotient was 45.17, and 79% had significant comorbidities. The prevalence of depression in mothers was 79%; it was more in mothers of female ID child, ID child with significant comorbidities, severer forms of retardation, and with higher levels of anxiety in the mother. Conclusions: The prevalence of depression in mothers of ID children in the present study seems to be much greater than those reported from the previous studies. The determination of predictors of depression among mothers of ID children may help health professionals in identifying mothers at risk. Regular screening of mothers of ID children should be included in the protocol for management.
背景:智力残疾是一种永久性且高度致残的疾病。残疾儿童的出生使母亲和其他家庭成员产生复杂的感情。本研究旨在调查ID的现象学及其母亲的抑郁症患病率。目的:了解ID儿童母亲的抑郁症患病率、各种社会人口学变量的影响及其与抑郁症的临床相关性。研究设计:横断面研究。材料和方法:共有100名被诊断为ID的患者被纳入研究。以一种特殊的形式收集客观数据,并用贝克焦虑量表和贝克抑郁量表对这些患者的母亲进行评估。结果:ID患者的平均年龄为11.52岁,平均接受过3.01年的教育,平均诊断年龄为6.01岁,平均智商为45.17,79%的患者有显著的合并症。母亲的抑郁症患病率为79%;在女性ID儿童的母亲中更为常见,ID儿童有显著的合并症,有更严重的发育迟缓,母亲的焦虑程度更高。结论:在本研究中,ID儿童母亲的抑郁症患病率似乎比以前的研究报告的要高得多。在ID儿童的母亲中确定抑郁症的预测因素可能有助于卫生专业人员识别有风险的母亲。应将ID儿童母亲的定期筛查纳入管理方案。
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引用次数: 11
Disproportionate dyspnea in a patient with pneumonia 肺炎患者不成比例的呼吸困难
Q4 Medicine Pub Date : 2017-03-01 DOI: 10.4103/0975-2870.202099
V. Moleyar, A. Bhat, Y. Madhusudan, D. Harsha
In severe pneumonia, dyspnea occurs due to hypoxia. Usually, in pneumonia, dyspnea is proportional to the extent of lung parenchymal lesion. When a patient with pneumonia presents with disproportionate dyspnea, other causes for dyspnea should be evaluated. Here, we present a 48-year-old female with pneumonia, found to have disproportionate dyspnea. Her hypoxia did not improve despite adequate antibiotic and oxygen therapy. On further enquiry, she admitted taking dapsone for leprosy. She had saturation gap diagnostic of methemoglobinemia. Diagnosis was confirmed by estimation of methemoglobin level in blood. She was treated with intravenous methylene blue and recovered. When a patient has disproportionate dyspnea, methemoglobinemia should be considered as a differential diagnosis.
在严重的肺炎中,呼吸困难是由于缺氧引起的。通常,在肺炎中,呼吸困难与肺实质病变的程度成正比。当肺炎患者出现不成比例的呼吸困难时,应评估引起呼吸困难的其他原因。在此,我们报告一位48岁的女性肺炎患者,发现有不成比例的呼吸困难。尽管给予充分的抗生素和氧气治疗,她的缺氧情况仍未改善。经进一步调查,她承认服用氨苯砜治疗麻风病。她有高铁血红蛋白血症的饱和间隙诊断。通过测定血中高铁血红蛋白水平确诊。她接受静脉注射亚甲基蓝治疗后康复。当患者有不成比例的呼吸困难时,高铁血红蛋白血症应被视为鉴别诊断。
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引用次数: 0
Study of fine-needle aspiration cytology of lymph node in rural area of Bastar District, Chhattisgarh 恰蒂斯加尔邦巴斯塔区农村地区淋巴结细针抽吸细胞学研究
Q4 Medicine Pub Date : 2017-03-01 DOI: 10.4103/0975-2870.202097
S. Badge, A. Ovhal, K. Azad, Avinash T Meshram
Aims and Objectives: Fine-needle aspiration cytology (FNAC) as the first line of investigation has assumed importance in diagnosing a variety of disease processes as it is rapid, simple, reliable, minimally invasive, and cost-effective procedure which can be used in outpatient setting. Lymphadenopathy is one of the most common clinical presentations of patients attending the outpatient department. This study was performed to find out the pattern of diseases in lymph node in the rural area of Bastar District of Chhattisgarh State. Materials and Methods: A prospective study of 310 cases of lymphadenopathy presenting to the Department of Pathology for 2 years from January 2014 to December 2015 was taken up for our study. FNAC was performed using a 22–24-gauge needle and 10 ml syringe. Two of the prepared smears were fixed in alcohol and stained with hematoxylin and eosin and Papanicolaou stain. Two smears were air-dried, one was stained with Leishman stain and the other kept unstained to be used for Ziehl–Neelsen staining whenever a cytological diagnosis of granulomatous disease was made and also in cases with abundant necrosis and suppuration. Results: Most common lesion found in our study was tubercular lymphadenitis, followed by granulomatous lymphadenitis and reactive hyperplasia. Conclusion: Our study highlighted the various cytomorphological patterns of lymphadenopathy and revealed a huge burden of tuberculous lymphadenitis in this region.
目的和目的:细针抽吸细胞学(FNAC)作为研究的第一线,在诊断各种疾病过程中具有重要意义,因为它是一种快速、简单、可靠、微创和成本效益高的程序,可用于门诊。淋巴结病是门诊病人最常见的临床表现之一。本研究旨在了解恰蒂斯加尔邦巴斯塔区农村地区淋巴结疾病的发病模式。材料和方法:我们对2014年1月至2015年12月在病理科就诊的310例淋巴结病进行了为期2年的前瞻性研究。使用22-24号针头和10毫升注射器进行FNAC。将两份制备的涂片固定在酒精中,并用苏木精和伊红以及巴氏染色。两份涂片风干,一份用利什曼染色,另一份保持未染色,以便在对肉芽肿性疾病进行细胞学诊断时以及在大量坏死和化脓的情况下进行Ziehl–Neelsen染色。结果:在我们的研究中发现最常见的病变是结核性淋巴结炎,其次是肉芽肿性淋巴结症和反应性增生。结论:我们的研究强调了淋巴结病的各种细胞形态学模式,并揭示了该地区结核性淋巴结炎的巨大负担。
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引用次数: 17
期刊
Medical Journal of Dr. D.Y. Patil University
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