首页 > 最新文献

Medical Journal of Dr. D.Y. Patil University最新文献

英文 中文
Study of fine-needle aspiration cytology of breast lumps in rural area of Bastar district, Chhattisgarh 恰蒂斯加尔邦巴斯塔尔农村地区乳腺肿块细针穿刺细胞学研究
Q4 Medicine Pub Date : 2017-07-01 DOI: 10.4103/MJDRDYPU.MJDRDYPU_250_16
S. Badge, A. Ovhal, K. Azad, Avinash T Meshram
Aims and Objectives: In India, breast cancer is the second most common cancer in women. The fine-needle aspiration cytology (FNAC) of breast lump is highly sensitive, easy to perform, and cost effective that can be carried out at outpatient department. The aim of this study is to identify the most common benign and malignant tumors of the breast lump on FNAC in our institute. Materials and Methods: The present study was carried out in the Pathology Department of our institute over 2 years from January 2014 to December 2015. Procedure is done using 24-gauge needle fitted on 10 ml disposable syringe in syringe holder. The wet smear fixed with ether-alcohol mixture stained with hematoxylin and eosin and papanicolaou stain. The air-dried smear stained with May-Grunwald Giemsa stain. Results: A total of 731 cases were obtained in the cytopathology section over 2 years from January 2014 to December 2015, out of which 220 (30.10%) cases were breast lump FNACs. Benign tumors contributed to 162 cases (73.64%) and malignant tumors to 58 cases (26.36%). Among benign tumor, fibroadenoma was the most common tumor which constituted 121 cases (55%). Infiltrating duct carcinoma was the most common malignant breast tumor in the present study comprising 53 cases (24.09%). Conclusion: The most common benign tumor in the present study was fibroadenoma and the most common malignant tumor was invasive ductal carcinoma.
目的:在印度,乳腺癌症是癌症中第二常见的女性。乳腺肿块的细针穿刺细胞学检查(FNAC)灵敏度高,操作简便,成本效益高,可在门诊进行。本研究的目的是在我们研究所的FNAC上识别最常见的乳腺肿块的良恶性肿瘤。材料与方法:本研究于2014年1月至2015年12月在我所病理科进行,历时2年。使用安装在注射器支架中的10ml一次性注射器上的24号针头完成该程序。湿涂片用乙醚-酒精混合物固定,苏木精-伊红染色,巴氏染色。空气干燥的涂片用May-Grunwald-Giemsa染色。结果:2014年1月至2015年12月,在2年的细胞病理切片中,共获得731例,其中220例(30.10%)为乳腺肿块FNAC。良性肿瘤162例(73.64%),恶性肿瘤58例(26.36%),其中以纤维腺瘤最常见,占121例(55%)。浸润性导管癌是最常见的乳腺恶性肿瘤,共53例(24.09%)。结论:本研究中最常见的良性肿瘤是纤维腺瘤,最常见的恶性肿瘤是侵袭性导管癌。
{"title":"Study of fine-needle aspiration cytology of breast lumps in rural area of Bastar district, Chhattisgarh","authors":"S. Badge, A. Ovhal, K. Azad, Avinash T Meshram","doi":"10.4103/MJDRDYPU.MJDRDYPU_250_16","DOIUrl":"https://doi.org/10.4103/MJDRDYPU.MJDRDYPU_250_16","url":null,"abstract":"Aims and Objectives: In India, breast cancer is the second most common cancer in women. The fine-needle aspiration cytology (FNAC) of breast lump is highly sensitive, easy to perform, and cost effective that can be carried out at outpatient department. The aim of this study is to identify the most common benign and malignant tumors of the breast lump on FNAC in our institute. Materials and Methods: The present study was carried out in the Pathology Department of our institute over 2 years from January 2014 to December 2015. Procedure is done using 24-gauge needle fitted on 10 ml disposable syringe in syringe holder. The wet smear fixed with ether-alcohol mixture stained with hematoxylin and eosin and papanicolaou stain. The air-dried smear stained with May-Grunwald Giemsa stain. Results: A total of 731 cases were obtained in the cytopathology section over 2 years from January 2014 to December 2015, out of which 220 (30.10%) cases were breast lump FNACs. Benign tumors contributed to 162 cases (73.64%) and malignant tumors to 58 cases (26.36%). Among benign tumor, fibroadenoma was the most common tumor which constituted 121 cases (55%). Infiltrating duct carcinoma was the most common malignant breast tumor in the present study comprising 53 cases (24.09%). Conclusion: The most common benign tumor in the present study was fibroadenoma and the most common malignant tumor was invasive ductal carcinoma.","PeriodicalId":36033,"journal":{"name":"Medical Journal of Dr. D.Y. Patil University","volume":"10 1","pages":"339"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42202459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Infection by multidrug-resistant Chryseobacterium indologenes in cases of obstructive uropathy: Case series with short review 多药耐药吲哚黄杆菌在梗阻性尿病中的感染:简短回顾的病例系列
Q4 Medicine Pub Date : 2017-07-01 DOI: 10.4103/MJDRDYPU.MJDRDYPU_201_16
M. Palewar, S. Mudshingkar, V. Dohe, R. Bharadwaj
Chryseobacterium spp. are Gram-negative, aerobic, nonfermentative, oxidase-positive and catalase-positive nonmotile bacilli that produce yellow to orange pigment. We report three cases of complicated urinary tract infections (UTIs) caused by Chryseobacterium indologenes in patients with obstructive uropathy. The first case was a known case of diabetes mellitus with right emphysematous pyelonephritis and obstructive uropathy due to prostate enlargement. The patient underwent dialysis for renal failure and subsequently developed UTI by multidrug-resistant C. indologenes. The second case was 72 years old known case of ischemic heart disease. He had acute retention of urine that was relieved after catheterization. He had obstructive uropathy due to transitional cell carcinoma of the bladder and had developed UTI due to C. indologenes. The third case was 38-year-old unmarried female admitted for difficulty in micturition and was catheterized for the same. Obstructive uropathy was due to two fibroids, first fibroid was 9.2 cm × 9.2 cm sized subserosal in the lower segment of the uterus on posterior wall (posterior cervical fibroid) and second fibroid was approximately 1.5 cm × 2.1 cm fundal fibroid; however, the patient developed UTI on the 7th day of catheterization due to C. indologenes. These cases were treated by relieving urinary obstruction and appropriate antibiotic treatment as per antibiotic susceptibility test results.
黄杆菌属革兰氏阴性,需氧,非发酵,氧化酶阳性和过氧化氢酶阳性的非运动杆菌,产生黄色到橙色的色素。我们报告了3例梗阻性尿路病变患者由吲哚黄杆菌引起的复杂尿路感染。第一个病例是已知的糖尿病合并右肺气性肾盂肾炎和前列腺肿大引起的梗阻性尿路病。患者因肾衰竭接受透析治疗,随后由耐多药吲哚原梭菌引起尿路感染。第二个病例是72岁已知的缺血性心脏病病例。他有急性尿潴留,导尿后缓解。他患有膀胱移行细胞癌引起的梗阻性尿路病变,并因产吲哚原梭菌而发展为尿路感染。第三例患者为38岁未婚女性,因排尿困难入院,留置导尿。梗阻性尿病由两个肌瘤引起,第一个肌瘤为子宫下段后壁浆膜下9.2 cm × 9.2 cm大小(宫颈后肌瘤),第二个肌瘤约为1.5 cm × 2.1 cm的基底肌瘤;然而,患者在置管第7天因吲哚原梭菌发生尿路感染。根据药敏试验结果,给予缓解尿路梗阻及适当抗生素治疗。
{"title":"Infection by multidrug-resistant Chryseobacterium indologenes in cases of obstructive uropathy: Case series with short review","authors":"M. Palewar, S. Mudshingkar, V. Dohe, R. Bharadwaj","doi":"10.4103/MJDRDYPU.MJDRDYPU_201_16","DOIUrl":"https://doi.org/10.4103/MJDRDYPU.MJDRDYPU_201_16","url":null,"abstract":"Chryseobacterium spp. are Gram-negative, aerobic, nonfermentative, oxidase-positive and catalase-positive nonmotile bacilli that produce yellow to orange pigment. We report three cases of complicated urinary tract infections (UTIs) caused by Chryseobacterium indologenes in patients with obstructive uropathy. The first case was a known case of diabetes mellitus with right emphysematous pyelonephritis and obstructive uropathy due to prostate enlargement. The patient underwent dialysis for renal failure and subsequently developed UTI by multidrug-resistant C. indologenes. The second case was 72 years old known case of ischemic heart disease. He had acute retention of urine that was relieved after catheterization. He had obstructive uropathy due to transitional cell carcinoma of the bladder and had developed UTI due to C. indologenes. The third case was 38-year-old unmarried female admitted for difficulty in micturition and was catheterized for the same. Obstructive uropathy was due to two fibroids, first fibroid was 9.2 cm × 9.2 cm sized subserosal in the lower segment of the uterus on posterior wall (posterior cervical fibroid) and second fibroid was approximately 1.5 cm × 2.1 cm fundal fibroid; however, the patient developed UTI on the 7th day of catheterization due to C. indologenes. These cases were treated by relieving urinary obstruction and appropriate antibiotic treatment as per antibiotic susceptibility test results.","PeriodicalId":36033,"journal":{"name":"Medical Journal of Dr. D.Y. Patil University","volume":"10 1","pages":"376"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45340371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Spectrum of lymph node lesions as determined by histopathology 由组织病理学确定的淋巴结病变谱
Q4 Medicine Pub Date : 2017-07-01 DOI: 10.4103/MJDRDYPU.MJDRDYPU_296_16
Pradhan M. Pagaro, B. Banerjee, A. Khandelwal, Aditi Pandey, A. Gambhir
Background and Objective: Lymph node lesions form a wide range of spectrum, exhibiting manifestations in both hematopoietic tissue and lympho reticular system. It is necessary to document the same spectrum in a particular region to understand the trend and diseases occurring frequently in that region. The range encompasses benign reactive changes to frank malignant lymphoma and metastatic deposits. Histopathology is considered to be the gold standard and its relevance to clinical diagnosis is studied here. Materials and Methods: A total of 200 cases were studied retrospectively in this study. Samples received were either biopsy or node resection specimens, and clinical history was recorded for each of them. Immunohistochemistry and special stains were performed as and when required. Results: Clinical diagnosis had a diagnostic accuracy of 71% approximately using histopathology as the gold standard. Most of the benign diseases were either reactive or tubercular lymphadenitis, whereas non-Hodgkin Follicular lymphoma had the maximum incidence among lymphomas. Conclusion: This study concluded that cervical group of superficial lymph nodes are most frequently encountered as palpable nodal swellings. The clinical suspicion of malignancy remains high in most of the cases due to the matted and enlarged presentation of lymph nodes. Histopathology revealed that only 33.5% of the cases to be malignant of which the most common was Follicular Lymphoma (non-Hodgkin type). The clinical accuracy of diagnosing malignant lesions thus coming to 71% approximately.
背景与目的:淋巴结病变具有广谱性,在造血组织和淋巴网状系统均有表现。有必要记录特定区域的相同频谱,以了解该区域经常发生的趋势和疾病。范围包括良性反应性改变到恶性淋巴瘤和转移性沉积。组织病理学被认为是金标准,其与临床诊断的相关性在这里进行了研究。材料与方法:对200例患者进行回顾性研究。收到的标本为活检或淋巴结切除标本,并记录其临床病史。需要时进行免疫组织化学和特殊染色。结果:以组织病理学为金标准,临床诊断准确率约为71%。良性病变多为反应性或结核性淋巴结炎,而非霍奇金滤泡性淋巴瘤发病率最高。结论:本研究认为颈部组浅表淋巴结最常出现可触及的淋巴结肿胀。临床怀疑恶性肿瘤仍然高,在大多数情况下,由于网状和扩大的表现淋巴结。组织病理学显示,只有33.5%的病例为恶性,其中最常见的是滤泡性淋巴瘤(非霍奇金型)。临床诊断恶性病变的正确率约为71%。
{"title":"Spectrum of lymph node lesions as determined by histopathology","authors":"Pradhan M. Pagaro, B. Banerjee, A. Khandelwal, Aditi Pandey, A. Gambhir","doi":"10.4103/MJDRDYPU.MJDRDYPU_296_16","DOIUrl":"https://doi.org/10.4103/MJDRDYPU.MJDRDYPU_296_16","url":null,"abstract":"Background and Objective: Lymph node lesions form a wide range of spectrum, exhibiting manifestations in both hematopoietic tissue and lympho reticular system. It is necessary to document the same spectrum in a particular region to understand the trend and diseases occurring frequently in that region. The range encompasses benign reactive changes to frank malignant lymphoma and metastatic deposits. Histopathology is considered to be the gold standard and its relevance to clinical diagnosis is studied here. Materials and Methods: A total of 200 cases were studied retrospectively in this study. Samples received were either biopsy or node resection specimens, and clinical history was recorded for each of them. Immunohistochemistry and special stains were performed as and when required. Results: Clinical diagnosis had a diagnostic accuracy of 71% approximately using histopathology as the gold standard. Most of the benign diseases were either reactive or tubercular lymphadenitis, whereas non-Hodgkin Follicular lymphoma had the maximum incidence among lymphomas. Conclusion: This study concluded that cervical group of superficial lymph nodes are most frequently encountered as palpable nodal swellings. The clinical suspicion of malignancy remains high in most of the cases due to the matted and enlarged presentation of lymph nodes. Histopathology revealed that only 33.5% of the cases to be malignant of which the most common was Follicular Lymphoma (non-Hodgkin type). The clinical accuracy of diagnosing malignant lesions thus coming to 71% approximately.","PeriodicalId":36033,"journal":{"name":"Medical Journal of Dr. D.Y. Patil University","volume":"10 1","pages":"343"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44312623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Vitamin D deficiency and its association with thyroid peroxidase antibodies positive hypothyroidism - Experience in a tertiary center in South India 维生素D缺乏及其与甲状腺过氧化物酶抗体阳性甲状腺功能减退症的关系——南印度一家三级中心的经验
Q4 Medicine Pub Date : 2017-07-01 DOI: 10.4103/MJDRDYPU.MJDRDYPU_252_16
J. Khare, Babul Reddy, S. Nalla, Prachi Srivastava, J. Wadhwa, P. Deb
Introduction: Vitamin D deficiency is one of the major health problems globally, and the role of Vitamin D as an immunomodulator has been recently emphasized. There is increasing evidence to suggest that Vitamin D plays a significant role in reducing the incidence of autoimmune diseases. However, at present, its role in autoimmune thyroid disease is not conclusive. Hence, in our study, we aimed to examine the relationship between thyroid peroxidase antibodies (TPOAbs) and Vitamin D deficiency in the hypothyroid patient. Subjects and Methods: One hundred and four known hypothyroid patients not on Vitamin D supplementation were included in the study. They were divided into two groups with TPOAb positive and TPOAb negative, and serum 25(OH) Vitamin D3 (25[OH] D3) was measured and compared in two groups. Thyroid hormones (TSH and T4) were also evaluated in all patients. Results: Serum 25(OH)D3 was significantly lower in TPOAb-positive patients than in TPOAb-negative patients with P = 0.038. Mean serum TSH was significantly high in TPOAb-positive hypothyroid patients than in TPOAb-negative patients with P = 0.047. Conclusion: Our study shows that patients with TPOAb positivity have more significant 25(OH)D3 deficiency and uncontrolled hypothyroidism. Our study encourages the advisability of screening for Vitamin D deficiency for all hypothyroid patients and 25(OH)D3 supplementation.
维生素D缺乏症是全球性的主要健康问题之一,维生素D作为免疫调节剂的作用近年来受到重视。越来越多的证据表明,维生素D在减少自身免疫性疾病的发病率方面起着重要作用。然而,目前对其在自身免疫性甲状腺疾病中的作用尚无定论。因此,在我们的研究中,我们旨在研究甲状腺功能减退患者甲状腺过氧化物酶抗体(TPOAbs)与维生素D缺乏之间的关系。研究对象和方法:104名未服用维生素D补充剂的已知甲状腺功能减退患者被纳入研究。将患者分为TPOAb阳性和TPOAb阴性两组,测定两组患者血清25(OH)维生素D3 (25[OH] D3)含量并进行比较。所有患者的甲状腺激素(TSH和T4)也进行了评估。结果:tpoab阳性患者血清25(OH)D3明显低于tpoab阴性患者,P = 0.038。tpoab阳性甲状腺功能减退患者的平均血清TSH显著高于tpoab阴性患者,P = 0.047。结论:我们的研究表明TPOAb阳性患者有更明显的25(OH)D3缺乏和不受控制的甲状腺功能减退。我们的研究鼓励对所有甲状腺功能减退患者筛查维生素D缺乏症和补充25(OH)D3的建议。
{"title":"Vitamin D deficiency and its association with thyroid peroxidase antibodies positive hypothyroidism - Experience in a tertiary center in South India","authors":"J. Khare, Babul Reddy, S. Nalla, Prachi Srivastava, J. Wadhwa, P. Deb","doi":"10.4103/MJDRDYPU.MJDRDYPU_252_16","DOIUrl":"https://doi.org/10.4103/MJDRDYPU.MJDRDYPU_252_16","url":null,"abstract":"Introduction: Vitamin D deficiency is one of the major health problems globally, and the role of Vitamin D as an immunomodulator has been recently emphasized. There is increasing evidence to suggest that Vitamin D plays a significant role in reducing the incidence of autoimmune diseases. However, at present, its role in autoimmune thyroid disease is not conclusive. Hence, in our study, we aimed to examine the relationship between thyroid peroxidase antibodies (TPOAbs) and Vitamin D deficiency in the hypothyroid patient. Subjects and Methods: One hundred and four known hypothyroid patients not on Vitamin D supplementation were included in the study. They were divided into two groups with TPOAb positive and TPOAb negative, and serum 25(OH) Vitamin D3 (25[OH] D3) was measured and compared in two groups. Thyroid hormones (TSH and T4) were also evaluated in all patients. Results: Serum 25(OH)D3 was significantly lower in TPOAb-positive patients than in TPOAb-negative patients with P = 0.038. Mean serum TSH was significantly high in TPOAb-positive hypothyroid patients than in TPOAb-negative patients with P = 0.047. Conclusion: Our study shows that patients with TPOAb positivity have more significant 25(OH)D3 deficiency and uncontrolled hypothyroidism. Our study encourages the advisability of screening for Vitamin D deficiency for all hypothyroid patients and 25(OH)D3 supplementation.","PeriodicalId":36033,"journal":{"name":"Medical Journal of Dr. D.Y. Patil University","volume":"10 1","pages":"355"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47349182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Family planning paradigms: Gender bias and its impact on Olympic gold medals 计划生育范式:性别偏见及其对奥运金牌的影响
Q4 Medicine Pub Date : 2017-07-01 DOI: 10.4103/MJDRDYPU.MJDRDYPU_72_17
A. Banerjee
{"title":"Family planning paradigms: Gender bias and its impact on Olympic gold medals","authors":"A. Banerjee","doi":"10.4103/MJDRDYPU.MJDRDYPU_72_17","DOIUrl":"https://doi.org/10.4103/MJDRDYPU.MJDRDYPU_72_17","url":null,"abstract":"","PeriodicalId":36033,"journal":{"name":"Medical Journal of Dr. D.Y. Patil University","volume":"10 1","pages":"323"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44424328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnostic implication of mean platelet volume in thrombocytopenia 血小板平均体积对血小板减少症的诊断意义
Q4 Medicine Pub Date : 2017-07-01 DOI: 10.4103/MJDRDYPU.MJDRDYPU_306_16
I. Gulati, H. Kumar, J. Sheth, I. Dey
Background: A well-known cause of thrombocytopenia is peripheral platelet destruction in which the circulating platelets are premature and large. Many times a bone marrow examination is conducted to find out the etiology of thrombocytopenia. Assessment of platelet parameters like mean platelet volume (MPV) generated by a hematology analyzer is also believed to be helpful for guiding the clinicians to identify such cases. Aims: This study aims to ascertain whether raised MPV correlates with thrombocytopenia due to hyperdestruction of platelets. Materials and Methods: This was 2 years unicentric prospective observational study which included 100 thrombocytopenic patients. Their clinical diagnosis, platelet counts, and MPV values were recorded. Peripheral blood smears (PBS) were also examined for megaplatelets. Each case was put in Group A (hyperdestructive etiology) or Group B (hypoproductive etiology). Results: Group A had 79 cases out of which 53 had an MPV value more than 10.5 fl. In the rest, although MPV was not prominently raised, the PBS did show megaplatelets. Group B had 21 cases, which were not associated with a high MPV. A receiver operating characteristic curve was plotted, and Youden's index was used to find out a cutoff value for MPV (8.5 fl) which gave the maximum sensitivity and specificity to discriminate thrombocytopenia cases of hyperdestructive etiology from the rest. Conclusion: MPV is an accurate, reliable, and easily obtained platelet parameter which is helpful in diagnosing the basic etiology of thrombocytopenia. It is also a less painful alternative than the bone marrow examination for the patient.
背景:血小板减少症的一个众所周知的原因是外周血小板破坏,其中循环血小板过早且大量。为了找出血小板减少症的病因,需要多次进行骨髓检查。血液学分析仪生成的血小板参数(如平均血小板体积(MPV))的评估也被认为有助于指导临床医生识别此类病例。目的:本研究旨在确定MPV升高是否与血小板过度破坏引起的血小板减少症相关。材料和方法:这是一项为期2年的单中心前瞻性观察研究,包括100名血小板减少症患者。记录他们的临床诊断、血小板计数和MPV值。外周血涂片(PBS)也检查了巨血小板。每个病例被分为A组(高破坏性病因)或B组(低生产性病因)。结果:A组有79例,其中53例MPV值超过10.5fl。其余病例,尽管MPV没有显著升高,但PBS显示出巨血小板。B组有21例,这些病例与高MPV无关。绘制受试者操作特征曲线,并使用Youden指数找出MPV(8.5fl)的临界值,该值对区分高破坏性病因的血小板减少症病例和其他病例具有最大的敏感性和特异性,并且易于获得血小板参数,这有助于诊断血小板减少症的基本病因。对于患者来说,这也是一种比骨髓检查痛苦更小的选择。
{"title":"Diagnostic implication of mean platelet volume in thrombocytopenia","authors":"I. Gulati, H. Kumar, J. Sheth, I. Dey","doi":"10.4103/MJDRDYPU.MJDRDYPU_306_16","DOIUrl":"https://doi.org/10.4103/MJDRDYPU.MJDRDYPU_306_16","url":null,"abstract":"Background: A well-known cause of thrombocytopenia is peripheral platelet destruction in which the circulating platelets are premature and large. Many times a bone marrow examination is conducted to find out the etiology of thrombocytopenia. Assessment of platelet parameters like mean platelet volume (MPV) generated by a hematology analyzer is also believed to be helpful for guiding the clinicians to identify such cases. Aims: This study aims to ascertain whether raised MPV correlates with thrombocytopenia due to hyperdestruction of platelets. Materials and Methods: This was 2 years unicentric prospective observational study which included 100 thrombocytopenic patients. Their clinical diagnosis, platelet counts, and MPV values were recorded. Peripheral blood smears (PBS) were also examined for megaplatelets. Each case was put in Group A (hyperdestructive etiology) or Group B (hypoproductive etiology). Results: Group A had 79 cases out of which 53 had an MPV value more than 10.5 fl. In the rest, although MPV was not prominently raised, the PBS did show megaplatelets. Group B had 21 cases, which were not associated with a high MPV. A receiver operating characteristic curve was plotted, and Youden's index was used to find out a cutoff value for MPV (8.5 fl) which gave the maximum sensitivity and specificity to discriminate thrombocytopenia cases of hyperdestructive etiology from the rest. Conclusion: MPV is an accurate, reliable, and easily obtained platelet parameter which is helpful in diagnosing the basic etiology of thrombocytopenia. It is also a less painful alternative than the bone marrow examination for the patient.","PeriodicalId":36033,"journal":{"name":"Medical Journal of Dr. D.Y. Patil University","volume":"10 1","pages":"370"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47329146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
Reply to “Letter to Editor”- Reproductive health awareness among adolescent girls of a government school in an urban slum of Pune city 对"给编辑的信"的答复-浦那市城市贫民窟一所公立学校的青春期女孩的生殖健康意识
Q4 Medicine Pub Date : 2017-07-01 DOI: 10.4103/MJDRDYPU.MJDRDYPU_70_17
P. Shankar, P. Dudeja
{"title":"Reply to “Letter to Editor”- Reproductive health awareness among adolescent girls of a government school in an urban slum of Pune city","authors":"P. Shankar, P. Dudeja","doi":"10.4103/MJDRDYPU.MJDRDYPU_70_17","DOIUrl":"https://doi.org/10.4103/MJDRDYPU.MJDRDYPU_70_17","url":null,"abstract":"","PeriodicalId":36033,"journal":{"name":"Medical Journal of Dr. D.Y. Patil University","volume":"10 1","pages":"397"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41874161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anesthesia for day-care surgeries: Current perspectives 日托手术的麻醉:当前观点
Q4 Medicine Pub Date : 2017-07-01 DOI: 10.4103/MJDRDYPU.MJDRDYPU_24_17
Sukhminder Jit Bajwa, Veenita Sharma, Ridhima Sharma, A. Singh
Day-care surgery has become a popular modality of surgical intervention throughout the globe. Numerous factors including the economic and financial issues are driving this therapeutic modality to a widespread acceptance among surgeons and anesthesiologists. Advancements in anesthesia and surgical techniques as well as availability of newer drugs are largely responsible for the progress of day-care surgeries. Numerous challenges are still faced by anesthesiologists and surgeons in carrying out day-care surgeries, especially in spite of these advancements, at resource-limited setups. The first right step in successfully delivering the day-care surgical services includes proper selection of the patients. The preanesthetic evaluation is highly essential in determining the suitability of the patient for day-care anesthesia and surgery as well as the formulation of various anesthetic plans and strategies. The current review is intended to highlight inherent challenges and probable solutions to them for this rapidly progressing anesthesia.
日托手术在全球范围内已成为一种流行的手术干预方式。包括经济和金融问题在内的许多因素正在推动这种治疗方式在外科医生和麻醉师中得到广泛接受。麻醉和手术技术的进步以及新药的可用性在很大程度上促成了日托手术的进步。麻醉师和外科医生在进行日托手术时仍然面临着许多挑战,特别是尽管有这些进步,在资源有限的情况下。成功提供日间护理手术服务的第一步是正确选择患者。麻醉前评估在确定患者是否适合日间护理麻醉和手术以及制定各种麻醉计划和策略方面非常重要。当前的综述旨在强调这种快速发展的麻醉的固有挑战和可能的解决方案。
{"title":"Anesthesia for day-care surgeries: Current perspectives","authors":"Sukhminder Jit Bajwa, Veenita Sharma, Ridhima Sharma, A. Singh","doi":"10.4103/MJDRDYPU.MJDRDYPU_24_17","DOIUrl":"https://doi.org/10.4103/MJDRDYPU.MJDRDYPU_24_17","url":null,"abstract":"Day-care surgery has become a popular modality of surgical intervention throughout the globe. Numerous factors including the economic and financial issues are driving this therapeutic modality to a widespread acceptance among surgeons and anesthesiologists. Advancements in anesthesia and surgical techniques as well as availability of newer drugs are largely responsible for the progress of day-care surgeries. Numerous challenges are still faced by anesthesiologists and surgeons in carrying out day-care surgeries, especially in spite of these advancements, at resource-limited setups. The first right step in successfully delivering the day-care surgical services includes proper selection of the patients. The preanesthetic evaluation is highly essential in determining the suitability of the patient for day-care anesthesia and surgery as well as the formulation of various anesthetic plans and strategies. The current review is intended to highlight inherent challenges and probable solutions to them for this rapidly progressing anesthesia.","PeriodicalId":36033,"journal":{"name":"Medical Journal of Dr. D.Y. Patil University","volume":"10 1","pages":"327"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41396393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Intrapulmonary bronchogenic cyst 肺内支气管源性囊肿
Q4 Medicine Pub Date : 2017-07-01 DOI: 10.4103/0975-2870.213927
S. Phatak, Neeraj A. Patange
Bronchogenic cysts are congenital anomaly caused by abnormal bronchial development from the primitive ventral foregut, which arises from cells isolated from the main pulmonary branching when lung bud separates from the primitive gut. We are reporting a case of 14-year-old boy who presented with nonspecific chest pain and cough.
支气管源性囊肿是由原始前肠腹侧支气管发育异常引起的先天性异常,由肺芽与原始肠分离时从肺主分支分离出的细胞引起。我们报告一例14岁的男孩谁提出了非特异性胸痛和咳嗽。
{"title":"Intrapulmonary bronchogenic cyst","authors":"S. Phatak, Neeraj A. Patange","doi":"10.4103/0975-2870.213927","DOIUrl":"https://doi.org/10.4103/0975-2870.213927","url":null,"abstract":"Bronchogenic cysts are congenital anomaly caused by abnormal bronchial development from the primitive ventral foregut, which arises from cells isolated from the main pulmonary branching when lung bud separates from the primitive gut. We are reporting a case of 14-year-old boy who presented with nonspecific chest pain and cough.","PeriodicalId":36033,"journal":{"name":"Medical Journal of Dr. D.Y. Patil University","volume":"10 1","pages":"394"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41469323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A comparative study of modified Hodge test and Carba NP test for detecting carbapenemase production in Gram-negative bacteria 改良Hodge试验和Carba-NP试验检测革兰氏阴性菌产碳青霉烯酶的比较研究
Q4 Medicine Pub Date : 2017-07-01 DOI: 10.4103/0975-2870.213930
S. Datta, R. Dey, J. Dey, Srijita Ghosh
Objective: The aim of this study was to evaluate the efficacy of the modified Hodge test (MHT) and Carba NP test for the detection of carbapenemase production on Gram-negative bacilli (GNB). Materials and Methods: A total of 816 well-characterized GNB isolated from various clinical samples received from both out- and hospitalized patients were included in the study. Out of those, 16.18% (132/816) were carbapenem-resistant on screening test. MHT and Carba NP test were carried out on all these carbapenem-resistant GNB isolates. Results: Out of the 132 isolates screened resistant during the study period, 75% (99/132) were positive for MHT and 86.4% (114/132) showed the presence of carbapenemase by Carba NP test. Conclusion: The advantage of the Carba NP test over MHT is that it is a rapid test where the results can be read in short time and it is easy to perform. The number of detected carbapenemase producers was significantly higher by Carba NP test though this finding can only be validated by molecular analysis of the strains.
目的:评价改良Hodge试验(MHT)和Carba-NP试验检测革兰氏阴性杆菌(GNB)产碳青霉烯酶的疗效。材料和方法:从门诊和住院患者的各种临床样本中分离出816个特征良好的GNB,纳入研究。其中,16.18%(132/816)在筛选试验中对碳青霉烯具有耐药性。对所有这些碳青霉烯类耐药GNB菌株进行了MHT和Carba-NP试验。结果:在研究期间筛选出的132个耐药菌株中,通过Carba NP试验,75%(99/132)的MHT阳性,86.4%(114/132)显示存在碳青霉烯酶。结论:与MHT相比,Carba NP测试的优点在于它是一种快速的测试,可以在短时间内读取结果,并且易于执行。Carba NP试验检测到的碳青霉烯酶产生者的数量明显更高,尽管这一发现只能通过菌株的分子分析来验证。
{"title":"A comparative study of modified Hodge test and Carba NP test for detecting carbapenemase production in Gram-negative bacteria","authors":"S. Datta, R. Dey, J. Dey, Srijita Ghosh","doi":"10.4103/0975-2870.213930","DOIUrl":"https://doi.org/10.4103/0975-2870.213930","url":null,"abstract":"Objective: The aim of this study was to evaluate the efficacy of the modified Hodge test (MHT) and Carba NP test for the detection of carbapenemase production on Gram-negative bacilli (GNB). Materials and Methods: A total of 816 well-characterized GNB isolated from various clinical samples received from both out- and hospitalized patients were included in the study. Out of those, 16.18% (132/816) were carbapenem-resistant on screening test. MHT and Carba NP test were carried out on all these carbapenem-resistant GNB isolates. Results: Out of the 132 isolates screened resistant during the study period, 75% (99/132) were positive for MHT and 86.4% (114/132) showed the presence of carbapenemase by Carba NP test. Conclusion: The advantage of the Carba NP test over MHT is that it is a rapid test where the results can be read in short time and it is easy to perform. The number of detected carbapenemase producers was significantly higher by Carba NP test though this finding can only be validated by molecular analysis of the strains.","PeriodicalId":36033,"journal":{"name":"Medical Journal of Dr. D.Y. Patil University","volume":"10 1","pages":"365"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49626646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
期刊
Medical Journal of Dr. D.Y. Patil University
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1