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Cardiogenic hydrops and placental thickening are independent predictors of maternal mirror syndrome 心源性积液和胎盘增厚是母体镜像综合征的独立预测因子。
IF 3.1 2区 医学 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2026-03-01 Epub Date: 2025-12-06 DOI: 10.1016/j.ajogmf.2025.101871
Brian A. Burnett MD, Christian M. Parobek MD, PhD, Ahmed A. Nassr MD PhD
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引用次数: 0
Letter to the editor regarding “The feasibility and effectiveness of using an adhesion barrier in preventing dysmenorrhea, pain, and niche-related problems after cesarean sections” 致编辑的关于“使用粘连屏障预防剖宫产术后痛经、疼痛和与生态位相关问题的可行性和有效性”的信。
IF 3.1 2区 医学 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2026-03-01 Epub Date: 2026-02-25 DOI: 10.1016/j.ajogmf.2025.101842
Qirun Li MMed
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引用次数: 0
Letter to the editor regarding “Effect of a mobility-encouragement protocol during induction of labor with an extra-amniotic balloon compared to routine care: a randomized controlled trial” 致编辑的信关于“与常规护理相比,羊膜外气囊引产时活动鼓励方案的效果:一项随机对照试验”。
IF 3.1 2区 医学 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2026-03-01 Epub Date: 2026-02-25 DOI: 10.1016/j.ajogmf.2025.101882
Yang Zhang MD, Qingling Kang MD, Rirong Qu MD, PhD
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引用次数: 0
Artificial intelligence in academic research publishing: updates, controversies, and considerations for pregnancy and perinatal research 学术研究出版中的人工智能:妊娠和围产期研究的更新、争议和考虑。
IF 3.1 2区 医学 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2026-03-01 Epub Date: 2026-01-01 DOI: 10.1016/j.ajogmf.2025.101885
Mariam Ayyash MD, MSCR , Amir Aviram MD , Nicole Krenitsky MD, MBA , Timothy Wen MD, MPH , Vincenzo Berghella MD
Artificial intelligence (AI) has rapidly transformed academic writing and publishing, progressing from simple grammar checkers and citation tools to sophisticated large language models capable of generating, synthesizing, and critically evaluating scientific content. A recent advancement in this space is the rise of deep research AI—agentic models that autonomously conduct structured reasoning to produce evidence-backed research outputs. While AI opens vast opportunities to enhance academic productivity, it also introduces significant ethical challenges. The challenge isn’t just to use AI; rather, to use it responsibly. As AI continues to reshape scholarly communication, it must be guided by clear oversight and ethical frameworks. This article explores AI’s expanding role in academic publishing, with a focus on its applications in manuscript preparation, peer review, and quality assessment. It also addresses the growing concerns surrounding authorship, research integrity, and accountability. We additionally outline key considerations unique to obstetrics and maternal–fetal medicine to guide responsible and field-appropriate AI use in perinatal research and publishing. Ultimately, the responsible integration of AI, balanced with human judgment and governed by rigorous standards, will be critical to ensuring both innovation and credibility in academic research.
人工智能(AI)已经迅速改变了学术写作和出版,从简单的语法检查和引用工具发展到能够生成、综合和批判性评估科学内容的复杂大型语言模型(llm)。这一领域的最新进展是深度研究人工智能的兴起——代理模型可以自主地进行结构化推理,以产生有证据支持的研究成果。虽然人工智能为提高学术生产力提供了巨大的机会,但它也带来了重大的伦理挑战。我们面临的挑战不仅仅是使用人工智能;而是负责任地使用它。随着人工智能继续重塑学术交流,它必须得到明确的监督和道德框架的指导。本文探讨了人工智能在学术出版中不断扩大的作用,重点介绍了人工智能在论文准备、同行评审和质量评估方面的应用。它还解决了围绕作者身份、研究诚信和问责制日益增长的担忧。我们还概述了产科和母胎医学特有的关键考虑因素,以指导围产期研究和出版中负责任和适合现场的人工智能使用。最终,人工智能的负责任整合,与人类的判断相平衡,并受到严格标准的约束,对于确保学术研究的创新和可信度至关重要。
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引用次数: 0
Maternal positions reduce occiput posterior malposition and improve vaginal birth: a systematic review and meta-analysis of randomized controlled trials 产妇体位减少枕后位错位,改善阴道分娩:随机对照试验的系统回顾和荟萃分析。
IF 3.1 2区 医学 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2026-03-01 Epub Date: 2025-12-16 DOI: 10.1016/j.ajogmf.2025.101880
Meilin Yang MD , Cheng Zhao MD , Shaojun Lin MS , Xiaoyue Guo MD , Jing Yang MD , Shenglian Ni BSc , Yan Zhao MS , Chunyang Ai MS , Yangyu Zhao MD

Objective

To evaluate the effect of changing maternal position in late pregnancy and the first stage of labor on rotation from occiput posterior (OP) to occiput anterior (OA) and subsequent maternal-fetal outcomes.

Data sources

We systematically searched randomized controlled trials (RCTs) from the databases including PubMed, Embase, and Cochrane Library without language restriction, spanning from their inception to May 11, 2025. Registration PROSPERO (CRD420251050400).

Study eligibility criteria

The following PICOS criteria were included:(1) Population (P): singleton pregnancies in late pregnancy (≥37 weeks of gestation) or the first stage of labor. (2) Intervention (I): maternal positions. (3) Comparison (C): non-intervention position or unrestricted maternal activities. (4) Outcomes (O): number of participants who attained OA. (5) Study design (S):RCTs.

Study appraisal and synthesis methods

Separate meta-analyses were conducted for all RCTs and for trustworthy RCTs identified using the OBGYN Editors' Integrity Group criteria. Pooled relative risks (RR) and standard mean differences (SMD) with 95% CIs were calculated. Publication bias was assessed.

Results

A meta-analysis of four trustworthy RCTs (n=922) from the first stage of labor demonstrated that positional intervention significantly increased OP to OA rotation (pooled RR=1.68, 95% CI=1.09−2.60; I²=66.3%). Moreover, when initiated at 3-5 cm dilation with a prolonged protocol (targeted hourly or continuous duration), the intervention yielded even greater benefits for rotation (pooled RR=2.45, 95% CI=1.63−3.67; I²=0.0%), and also significantly increased rates of both vaginal delivery (pooled RR=1.22, 95% CI=1.06−1.41; I²=0.0%) and spontaneous vaginal delivery (SVD) (pooled RR=1.39, 95% CI=1.05−1.84; I²=0.0%). Consistent benefits persisted in an analysis of all ten RCTs, remaining significant after adjustment for publication bias. Subgroup analyses of these ten RCTs indicated that the lateral position with upper thigh flexed benefited SVD. Additionally, two late-pregnancy studies (n=2647) assessed maternal position for OP fetuses, but methodological differences precluded meta-analysis.

Conclusions

Intrapartum maternal position can promote OP to OA rotation and vaginal delivery, but antenatal evidence remains inconclusive and lacking.
目的:探讨妊娠晚期及产程第一阶段产妇体位变化对枕后位(OP)转枕前位(OA)及随后母胎结局的影响。数据来源:我们系统地从PubMed、Embase和Cochrane图书馆等数据库中检索随机对照试验(rct),检索时间从试验开始到2025年5月11日,无语言限制。注册PROSPERO (CRD420251050400)。研究资格标准:包括以下PICOS标准:(1)人群(P):妊娠晚期(≥37周)或第一产程的单胎妊娠。(2)干预(一):产妇位置。(3)比较(C):不干预位置或不受限制的产妇活动。(4) Outcomes (O):达到OA的参与者人数。(5)研究设计(S):随机对照试验。研究评估和综合方法:对所有随机对照试验和使用OBGYN编辑完整性组标准确定的可信随机对照试验进行单独的荟萃分析。计算合并相对危险度(RR)和95% ci的标准平均差异(SMD)。评估发表偏倚。结果:对4个可靠的rct (n=922)的荟萃分析显示,体位干预显著增加了OP到OA的旋转(合并RR = 1.68,95% CI = 1.09至2.60;I² = 66.3%)。此外,当开始在3 - 5厘米扩张延长协议(针对每小时或持续时间),旋转的干预带来更大的利益(汇集RR = 2.45,95% CI = 1.63到3.67;我² = 0.0%),并显著提高利率的阴道分娩(汇集RR = 1.22,95% CI = 1.06到1.41;我² = 0.0%)和自发的阴道分娩(计算)(汇集RR = 1.39,95% CI = 1.05到1.84;我² = 0.0%)。在所有10项随机对照试验的分析中,一致的获益持续存在,在调整发表偏倚后仍然显著。这10项随机对照试验的亚组分析表明,侧位和大腿上部屈曲有利于SVD。此外,两项晚期妊娠研究(n = 2,647)评估了OP胎儿的母体体位,但方法学差异妨碍了meta分析。结论:产时产妇体位可促进OP向OA旋转和阴道分娩,但产前证据尚不明确和缺乏。
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引用次数: 0
Lighting the way: indocyanine green–guided laparoscopic transabdominal cerclage in pregnancy 照亮道路:吲哚菁绿色引导下的妊娠腹腔镜经腹环扎术。
IF 3.1 2区 医学 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2026-03-01 Epub Date: 2025-10-06 DOI: 10.1016/j.ajogmf.2025.101788
Matteo Pavone MD , Chiara Innocenzi MD , Nicola Macellari MD , Chiara Cantarini MD , Nazario Foschi PhD , Angela Botta MD , Chiara Tersigni PhD , Tullio Ghi PhD , Anna Fagotti PhD , Denis Querleu MD , Francesco Fanfani PhD , Nicolò Bizzarri PhD
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引用次数: 0
Effect of dental treatments on reduction of preterm birth: a systematic review and meta-analysis 牙科治疗对减少早产的影响:系统回顾和荟萃分析。
IF 3.1 2区 医学 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2026-03-01 Epub Date: 2025-12-18 DOI: 10.1016/j.ajogmf.2025.101884
Camille Thomas MD, MPH , Shakil Ahmed MPH , Vincenzo Berghella MD , Romina Brignardello-Petersen DDS, PhD , Mohamed El-Rabbany DDS, PhD , Catherine Devion MLS , Stefania Ronzoni MD, PhD

Objective

Periodontal disease is associated with increased risk of preterm birth. Effective management during pregnancy may reduce preterm birth, though clinical trial evidence has been inconsistent. This study aimed to assess whether treating dental disease during pregnancy reduces preterm birth.

Data Sources

A systematic search was performed of EMBASE, MEDLINE, PubMed, Cochrane Library, and trial registries up to December 2023 and re-run in January 2025.

Study Eligibility Criteria

Randomized controlled trials (RCTs) enrolling pregnant persons with any dental disease randomized to receive dental treatment vs no treatment were included. No language restriction was applied.

Study Appraisal and Synthesis Methods

Data were independently extracted by two researchers and assessed for risk of bias using the Cochrane Risk of Bias tool, RoB 2. A random effect meta-analysis was performed with the Mantel–Haenszel variance estimate. Certainty of evidence (COE) was assessed using GRADE. The main outcome was preterm birth (<37 weeks’ gestation). Data on low birth weight were also collected.

Results

Fourteen RCTs (8316 participants) were included. Interventions included scaling and root planing (SRP) alone (8 RCTs), SRP with chlorhexidine mouthwash (4 RCTs), and cetylpyridinium chloride mouthwash (2 RCTs). Meta-analysis and GRADE assessment found moderate-certainty evidence suggesting that periodontal treatment results in a 15% relative risk reduction of preterm birth (risk ratio [RR] 0.85; 95% CI 0.71–1.02) compared to minimal periodontal treatment or no treatment (absolute difference 20 fewer preterm births per 1000 individuals; 95% CI from 39 fewer to 3 more). It is uncertain whether the addition of chlorhexidine mouthwash to SRP reduces preterm birth rates (RR 0.49, 95% CI 0.23–1.04, very low COE).

Conclusion

This meta-analysis, the largest and most up-to-date on this topic, suggests that treating periodontal disease during pregnancy may reduce the risk of preterm birth. However, limitations, such as the risk of bias and variations in populations and treatment, highlight the need for well-powered RCTs with low risk of bias to evaluate the most effective dental treatment strategies. Future studies should focus on established dental disease severity and explore different dental treatment strategies, including antimicrobial mouthwash.
目的:牙周病与早产风险增加有关。妊娠期的有效管理可能减少早产,尽管临床试验证据并不一致。本研究旨在评估在怀孕期间治疗牙病是否能减少早产。数据来源:系统检索EMBASE、MEDLINE、PubMed、Cochrane图书馆和试验注册库,检索截止至2023年12月,并于2025年1月重新检索。研究资格标准:随机对照试验(rct)纳入任何牙科疾病的孕妇,随机接受牙科治疗和未接受治疗。没有使用语言限制。研究评价和综合方法:数据由两名研究人员独立提取,并使用Cochrane风险偏倚工具RoB 2评估偏倚风险。随机效应荟萃分析采用Mantel-Haenszel方差估计。使用GRADE评估证据的确定性。主要结局为早产(结果:纳入14项随机对照试验(8316名受试者)。干预措施包括单独刮治和刨根(SRP)(8项随机对照试验)、SRP联合氯己定漱口水(4项随机对照试验)和氯化十六烷基吡啶漱口水(2项随机对照试验)。荟萃分析和GRADE评估发现中等确定性的证据表明,与最少的牙周治疗或不治疗相比,牙周治疗可使早产的相对风险降低15% (RR 0.85; 95% CI 0.71-1.02)(绝对差异为每1000人少早产20例;95% CI从少39例到多3例)。不确定在SRP中加入氯己定漱口水是否能降低早产率(RR 0.49, 95% CI 0.23-1.04,证据确定性非常低)。结论:该荟萃分析是该主题中最大和最新的荟萃分析,表明在怀孕期间治疗牙周病可能降低早产的风险。然而,局限性,如人群和治疗的偏倚风险和差异,强调需要低偏倚风险的高功率随机对照试验来评估最有效的牙科治疗策略。未来的研究应关注已确定的牙病严重程度,并探索不同的牙齿治疗策略,包括抗菌漱口水。
{"title":"Effect of dental treatments on reduction of preterm birth: a systematic review and meta-analysis","authors":"Camille Thomas MD, MPH ,&nbsp;Shakil Ahmed MPH ,&nbsp;Vincenzo Berghella MD ,&nbsp;Romina Brignardello-Petersen DDS, PhD ,&nbsp;Mohamed El-Rabbany DDS, PhD ,&nbsp;Catherine Devion MLS ,&nbsp;Stefania Ronzoni MD, PhD","doi":"10.1016/j.ajogmf.2025.101884","DOIUrl":"10.1016/j.ajogmf.2025.101884","url":null,"abstract":"<div><h3>Objective</h3><div>Periodontal disease is associated with increased risk of preterm birth. Effective management during pregnancy may reduce preterm birth, though clinical trial evidence has been inconsistent. This study aimed to assess whether treating dental disease during pregnancy reduces preterm birth.</div></div><div><h3>Data Sources</h3><div>A systematic search was performed of EMBASE, MEDLINE, PubMed, Cochrane Library, and trial registries up to December 2023 and re-run in January 2025.</div></div><div><h3>Study Eligibility Criteria</h3><div>Randomized controlled trials (RCTs) enrolling pregnant persons with any dental disease randomized to receive dental treatment vs no treatment were included. No language restriction was applied.</div></div><div><h3>Study Appraisal and Synthesis Methods</h3><div>Data were independently extracted by two researchers and assessed for risk of bias using the Cochrane Risk of Bias tool, RoB 2. A random effect meta-analysis was performed with the Mantel–Haenszel variance estimate. Certainty of evidence (COE) was assessed using GRADE. The main outcome was preterm birth (&lt;37 weeks’ gestation). Data on low birth weight were also collected.</div></div><div><h3>Results</h3><div>Fourteen RCTs (8316 participants) were included. Interventions included scaling and root planing (SRP) alone (8 RCTs), SRP with chlorhexidine mouthwash (4 RCTs), and cetylpyridinium chloride mouthwash (2 RCTs). Meta-analysis and GRADE assessment found moderate-certainty evidence suggesting that periodontal treatment results in a 15% relative risk reduction of preterm birth (risk ratio [RR] 0.85; 95% CI 0.71–1.02) compared to minimal periodontal treatment or no treatment (absolute difference 20 fewer preterm births per 1000 individuals; 95% CI from 39 fewer to 3 more). It is uncertain whether the addition of chlorhexidine mouthwash to SRP reduces preterm birth rates (RR 0.49, 95% CI 0.23–1.04, very low COE).</div></div><div><h3>Conclusion</h3><div>This meta-analysis, the largest and most up-to-date on this topic, suggests that treating periodontal disease during pregnancy may reduce the risk of preterm birth. However, limitations, such as the risk of bias and variations in populations and treatment, highlight the need for well-powered RCTs with low risk of bias to evaluate the most effective dental treatment strategies. Future studies should focus on established dental disease severity and explore different dental treatment strategies, including antimicrobial mouthwash.</div></div>","PeriodicalId":36186,"journal":{"name":"American Journal of Obstetrics & Gynecology Mfm","volume":"8 3","pages":"Article 101884"},"PeriodicalIF":3.1,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145800651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prenatal risk factors of maternal mirror syndrome in hydropic fetuses 积水胎儿母体镜像综合征的产前危险因素分析。
IF 3.1 2区 医学 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2026-03-01 Epub Date: 2026-02-25 DOI: 10.1016/j.ajogmf.2025.101870
Fang Chen BSc, Dong-Zhi Li MD, PhD
{"title":"Prenatal risk factors of maternal mirror syndrome in hydropic fetuses","authors":"Fang Chen BSc,&nbsp;Dong-Zhi Li MD, PhD","doi":"10.1016/j.ajogmf.2025.101870","DOIUrl":"10.1016/j.ajogmf.2025.101870","url":null,"abstract":"","PeriodicalId":36186,"journal":{"name":"American Journal of Obstetrics & Gynecology Mfm","volume":"8 3","pages":"Article 101870"},"PeriodicalIF":3.1,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147318697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assisted reproductive technology is not associated with a short cervix: secondary analysis of the nuMoM2b dataset 辅助生殖技术与短子宫颈无关:nuMoM2b数据集的二次分析。
IF 3.1 2区 医学 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2026-03-01 Epub Date: 2026-02-25 DOI: 10.1016/j.ajogmf.2025.101886
Andriana H. Velmahos BS, Stylianos Vagios MD, PhD, Michael House MD
{"title":"Assisted reproductive technology is not associated with a short cervix: secondary analysis of the nuMoM2b dataset","authors":"Andriana H. Velmahos BS,&nbsp;Stylianos Vagios MD, PhD,&nbsp;Michael House MD","doi":"10.1016/j.ajogmf.2025.101886","DOIUrl":"10.1016/j.ajogmf.2025.101886","url":null,"abstract":"","PeriodicalId":36186,"journal":{"name":"American Journal of Obstetrics & Gynecology Mfm","volume":"8 3","pages":"Article 101886"},"PeriodicalIF":3.1,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147318624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reply to letter to the editor regarding “Effect of a mobility-encouragement protocol during induction of labor with an extra-amniotic balloon compared to routine care: a randomized controlled trial” 回复关于“与常规护理相比,羊膜外气囊引产时活动鼓励方案的效果:一项随机对照试验”的致编辑的信。
IF 3.1 2区 医学 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2026-03-01 Epub Date: 2026-02-25 DOI: 10.1016/j.ajogmf.2025.101883
Liat Mor MD , Eran Weiner MD , Noa Gonen MD
{"title":"Reply to letter to the editor regarding “Effect of a mobility-encouragement protocol during induction of labor with an extra-amniotic balloon compared to routine care: a randomized controlled trial”","authors":"Liat Mor MD ,&nbsp;Eran Weiner MD ,&nbsp;Noa Gonen MD","doi":"10.1016/j.ajogmf.2025.101883","DOIUrl":"10.1016/j.ajogmf.2025.101883","url":null,"abstract":"","PeriodicalId":36186,"journal":{"name":"American Journal of Obstetrics & Gynecology Mfm","volume":"8 3","pages":"Article 101883"},"PeriodicalIF":3.1,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147318627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
American Journal of Obstetrics & Gynecology Mfm
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