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Using Smart Displays to Implement an eHealth System for Older Adults With Multiple Chronic Conditions: Randomized Controlled Trial. 使用智能显示器为患有多种慢性病的老年人实施电子健康系统:一项随机对照试验。
IF 4.8 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-11-18 DOI: 10.2196/75991
Gina Landucci, David H Gustafson, Marie-Louise Mares, Klaren Pe-Romashko, John J Curtin, Yaxin Hu, Adam Maus, Kasey Thompson, Sydney Saunders, Kaitlyn Brown, Judith Woodburn, Bilge Mutlu
<p><strong>Background: </strong>Smart displays and speakers offer voice interaction, which may be more accessible and appealing to older adults with chronic pain and other multimorbid conditions. Previous trials found stronger socioemotional benefits of ElderTree (vs control) among those with high primary care use and multiple chronic conditions.</p><p><strong>Objective: </strong>This study aims to test whether older adults with chronic pain and multiple other chronic conditions use and benefit more from ElderTree, an eHealth intervention targeting pain and quality of life, when delivered on a smart display.</p><p><strong>Methods: </strong>We recruited 269 participants from the University of Wisconsin-Madison health system and community organizations and randomly assigned 1:1:1 to (1) smart display with internet and ElderTree, plus usual care; (2) touchscreen laptop with internet and ElderTree, plus usual care; or (3) usual care alone. Participants were aged ≥60 years, had a chronic pain diagnosis or reported chronic pain, and at least 3 common chronic conditions. Primary outcomes were pain interference and psychosocial quality of life. Data sources were baseline, 4-month, and 8-month surveys and continuous ElderTree usage data.</p><p><strong>Results: </strong>No significant differences were found between the laptop versus smart display groups for pain interference (b=-0.11, 95% CI -1.07 to 0.85; P=.82) or psychosocial quality (b=-0.21, 95% CI -0.96 to 0.55; P=.56), nor between the combined laptop+smart display group versus control group for either outcome (pain interference: b=-0.41, 95% CI -1.23 to 0.41; P=.33; psychosocial quality of life: b=0.04, 95% CI -0.61 to 0.69; P=.90). Mediation was not tested because effects on primary outcomes were nonsignificant. Gender did not moderate the effect of laptop versus smart display groups in pain interference (b=-1.56, 95% CI -3.56 to 0.44; P=.13). Gender did moderate the effect of the combined laptop+smart display group versus control group (b=1.91, 95% CI 0.11 to 3.71; P=.04). Women showed a significant decrease in pain interference (b=-0.69, 95% CI -1.29 to -0.10; P=.02), whereas women in the control group showed no significant change (b=0.25, 95% CI -0.53 to 1.04; P=.53). Men in the combined group showed a nonsignificant decrease (b=-0.67, 95% CI -1.47 to 0.14; P=.10), whereas men in the control group showed a significant decrease (b=-1.61, 95% CI -2.88 to -0.35; P=.01). Participants assigned to the laptop versus smart display used ElderTree more frequently and had more favorable perceptions. Analyses of secondary and exploratory outcomes showed no significant differences between groups.</p><p><strong>Conclusions: </strong>We found no significant differences between the combined ElderTree group and the control group for changes over time in any primary, secondary, or exploratory outcomes. Moderation analyses indicated that only gender moderated study arm effects, and only for the laptop+smart displa
背景:智能显示器和智能扬声器提供了轻松的语音交互,对于患有慢性疼痛和其他多病慢性疾病的老年人来说,这可能更容易获得和吸引人。先前的ElderTree试验发现,对于初级保健使用率高的老年人和患有多种慢性疾病的老年人,ElderTree的社会情感益处(与对照组相比)更强,并且女性的社会情感益处强于男性。目的:本研究测试了患有慢性疼痛的老年人,在多种其他慢性疾病的背景下,如果给他们智能显示器而不是笔记本电脑进行干预,是否会更多地使用ElderTree,并从中获益,ElderTree是一种针对疼痛和生活质量的数字/电子健康干预,以及智能显示器组和笔记本电脑组是否会相对于没有设备或无法进行干预的对照组显示出益处。方法:在一项非盲、随机对照试验中,从威斯康星大学麦迪逊分校家庭医学和普通内科系统(UW Health)以及麦迪逊、密尔沃基和伯洛伊特地区的社区组织招募了269名患有慢性疼痛和至少3种高风险慢性疾病的参与者,并按1:1:1的比例分配到(1)有互联网接入和接骨树的智能显示器,以及他们的日常护理;(2)可上网的触屏笔记本电脑和ElderTree,以及日常护理;或者(3)单独进行常规护理。所有参与者年龄在60岁或以上,有慢性疼痛诊断和/或报告慢性疼痛,并且至少有三种常见的慢性疾病。主要结局是疼痛干扰和心理社会生活质量。随着时间的推移,研究组(ElderTree vs主动对照组)对主要结果变化的影响的拟议中介是4个月时ElderTree的使用(仅适用于ElderTree组)、能力、相关性、动机、锻炼和疼痛强度。调节因素是性别、慢性病数量和技术使用障碍。数据来源是基线、4个月和8个月的调查,并持续收集ElderTree的使用情况。结果:笔记本电脑组与智能显示器组之间疼痛干扰随时间的变化无显著差异(臂x时间交互作用b = -0.11, 95% CI -1.07至0.85;p = 0.82)或心理社会生活质量随时间的变化(臂x时间交互作用b = -0.21, 95% CI -0.96至0.55,p = 0.56)。笔记本电脑+智能显示器组合组与对照组在疼痛干扰随时间变化(臂x时间相互作用b = -0.41, 95% Cl -1.23至0.41;p = 0.33)和心理社会生活质量随时间变化(臂x时间相互作用:b = 0.04, 95% Cl -0.61至0.69;p = 0.90)方面也无显著差异。由于研究组对主要结局的影响不显著,因此未对主要结局进行中介检验。性别并没有调节笔记本电脑组与智能显示器组对疼痛干扰随时间变化的影响(b = -1.56, CI -3.56至0.44,p = 0.13)。与对照组相比,性别确实会调节笔记本电脑+智能显示器组合组的效果(b = 1.91, CI 0.11至3.71,p = 0.037)。笔记本电脑+智能显示器组合组的女性随着时间的推移,疼痛干扰显著减少(b = -0.69, CI -1.29至-0.10,p = 0.022);对照组无显著差异(b = 0.25, CI -0.53 ~ 1.04, p = 0.53)。笔记本电脑+智能显示器组合组男性无显著下降(b = -0.67, CI -1.47至0.14,p = .10);对照组明显降低(b = -1.61, CI = -2.88 ~ -0.35, p = 0.013)。被分配到笔记本电脑(与智能显示器相比)的参与者更频繁地使用ElderTree,并且对其有更积极的看法。然而,那些使用智能显示器的人使用的时间更长。次要和探索性结果分析显示,笔记本电脑组和智能显示器组之间、笔记本电脑+智能显示器组合组与对照组之间没有显著差异。结论:我们发现ElderTree联合治疗组和对照组在任何主要、次要或探索性结果随时间的变化上没有显著差异。调节分析表明,只有性别调节了研究组的影响,并且只有笔记本电脑+智能显示器组与对照组对两个主要结果随时间变化的影响。临床试验:ClinicalTrials.gov NCT04798196。国际注册报告:RR2-10.2196/37522。
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引用次数: 0
Factors Associated With the Ability To Keep Up With Technology Developments: Findings From a National Multigenerational Cross-Sectional Survey in Sweden. 与跟上技术发展能力相关的因素:瑞典一项全国多代人横断面调查的结果。
IF 4.8 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-11-14 DOI: 10.2196/77930
Jens Offerman, Sofi Fristedt, Steven M Schmidt, Susanne Iwarsson

Background: Digital technologies are increasingly central to supporting autonomy, health, and social participation in later life. However, disparities persist in the ability to keep up with technological developments, affecting individuals' opportunities to benefit from digital health and social innovations.

Objective: This study aimed to investigate factors associated with individuals' self-reported ability to keep up with technological developments, focusing on generational differences, attitudes toward digital tools, and sociodemographic characteristics.

Methods: We conducted a national cross-sectional online survey in Sweden with 2121 respondents aged 30 to 39 years, 50 to 59 years, and 70 to 79 years. Logistic regression analyses were used to identify associations between self-reported ability to keep up with technology and independent variables, including attitudes toward information and communication technology, gender, education, self-rated economic situation, and general health.

Results: Most respondents reported being able to keep up with technological developments. Compared to the oldest generation (70-79 years), participants aged 30 to 39 years had 188% higher odds (odds ratio [OR] 2.88, 95% CI 1.84-4.53) of reporting they kept up with technology developments, and women had lower odds than men (OR 0.52, 95% CI 0.39-0.70). Positive attitudes toward information and communication technology being user-friendly (OR 1.81, 95% CI 1.21-2.73), timesaving (OR 2.03, 95% CI 1.44-2.87), and increasing independence (OR 1.99, 95% CI 1.33-2.96) were also significantly associated with keeping up.

Conclusions: These findings suggest that digital inclusion in aging societies is shaped by complex and intersecting factors that go beyond age. Promoting equitable digital engagement requires addressing attitudinal, economic, and gender-related barriers and fostering inclusive technology design and support systems for both current and future generations of older adults.

背景:数字技术在支持老年生活中的自主性、健康和社会参与方面越来越重要。然而,在跟上技术发展的能力方面仍然存在差距,影响了个人从数字卫生和社会创新中受益的机会。目的:本研究旨在探讨与个人自我报告的跟上技术发展能力相关的因素,重点关注代际差异、对数字工具的态度和社会人口特征。方法:我们在瑞典进行了一项全国性的横断面在线调查,有2121名受访者,年龄为30至39岁,50至59岁,70至79岁。使用Logistic回归分析来确定自我报告的跟上技术的能力与自变量之间的关联,自变量包括对信息和通信技术的态度、性别、教育、自评的经济状况和一般健康状况。结果:大多数受访者表示能够跟上技术发展。与最年长的一代(70-79岁)相比,30 - 39岁的参与者报告自己跟上技术发展的几率高出188%(比值比[OR] 2.88, 95% CI 1.84-4.53),女性的比值低于男性(OR 0.52, 95% CI 0.39-0.70)。对信息通信技术用户友好(OR 1.81, 95% CI 1.21-2.73),节省时间(OR 2.03, 95% CI 1.44-2.87)和增加独立性(OR 1.99, 95% CI 1.33-2.96)的积极态度也与保持保持显著相关。结论:这些发现表明,老龄化社会中的数字包容受到年龄以外的复杂和交叉因素的影响。促进公平的数字参与需要解决态度、经济和性别方面的障碍,并为当前和未来的老年人建立包容性的技术设计和支持系统。
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引用次数: 0
Risk Factors for Community-Dwelling Older Adults Dropping Out of Self-Guided, Remote, and Web-Based Longitudinal Research: Predictive Modeling of Data from the Web-LABrainS Platform. 社区居住老年人退出自我引导、远程和基于网络的纵向研究的风险因素:来自Web-LABrainS平台数据的预测建模。
IF 4.8 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-11-13 DOI: 10.2196/68826
Luke Daniel Braun, H Raymond Allen, Jeffrey N Keller
<p><strong>Background: </strong>Little is currently known regarding the feasibility of using a self-guided, remote, web-based platform as the basis for a longitudinal study of aging in community-dwelling older adults (OAs). This study describes the feasibility and risk factors for participant dropout found when using this approach as part of the web-based Louisiana Aging Brain Study (web-LABrainS).</p><p><strong>Objective: </strong>This study used data from 402 participants in the web-LABrainS effort to determine the feasibility of using a self-guided, remote, and web-based platform as the basis for conducting longitudinal research in community-dwelling older adults. Additionally, we sought to determine the risk factors associated with participant dropout over a 12-month period in web-LABrainS and determine whether the same risk factors associated with dropout from in-clinic longitudinal studies were observed in web-LABrainS dropouts.</p><p><strong>Methods: </strong>Participants were enrolled in web-LABrainS on a rolling basis using word-of-mouth promotional efforts. Participants used the web-LABrainS platform to provide electronic consent, demographic and health information, answer questionnaires, and complete assessments as part of a self-guided and web-based effort off-site of the clinic (remote). Following completion of the baseline battery, participants were contacted by email every 6 months to complete another round of the web-LABrainS battery. The data in this study were collected from 402 participants, 217 (54.0%) of whom completed baseline, 6-month, and 12-month assessments (adherent participants) and 185 (46%) of whom participated in only the baseline and no subsequent web-LABrainS batteries (dropout participants).</p><p><strong>Results: </strong>Our study indicates that even with limited participant outreach and retention efforts, it is feasible to conduct longitudinal clinical research studies in community-dwelling OAs using a self-guided, remote, and web-based approach. In contrast to traditional in-clinic longitudinal studies, dropouts from web-LABrainS were not observed to be significantly different with respect to age, education, gender, marital status, or living alone (P=.67, .16, .29, .051, .31). Similar to traditional longitudinal studies, dropouts from web-LABrainS had significantly higher use of depression medication, decreased self-reported mobility, and decreased delayed recall performance (P=.007, .007, .004). Interestingly, no differences in technology use, comfort with technology, time of assessment, or consent to be contacted about future research were observed between adherents and dropouts (P=.17, .36, .47, .40). Predictive binary logistic regression yielded a moderately accurate model and further supported a negative association between cognitive ability and dropout (OR 0.77, 95% CI 0.61-0.96).</p><p><strong>Conclusions: </strong>Our study provides some of the first clinical evidence for the feasibility of conducting
背景:目前关于使用自我引导、远程、基于网络的平台作为社区居住老年人(OAs)老龄化纵向研究基础的可行性知之甚少。本研究描述了当使用此方法作为基于网络的路易斯安那脑老化研究(web-LABrainS)的一部分时发现的参与者退学的可行性和风险因素。目的:本研究使用来自web-LABrainS的402名参与者的数据,以确定使用自我引导、远程和基于网络的平台作为对社区居住的老年人进行纵向研究的基础的可行性。此外,我们试图确定与web-LABrainS参与者在12个月期间辍学相关的危险因素,并确定在临床纵向研究中是否观察到与web-LABrainS辍学相关的相同危险因素。方法:参与者被登记在网络labrains在滚动的基础上使用口头宣传的努力。参与者使用web-LABrainS平台提供电子同意、人口统计和健康信息、回答问卷并完成评估,作为诊所场外(远程)自我指导和基于网络的工作的一部分。在完成基线测试后,每6个月通过电子邮件与参与者联系,以完成另一轮web-LABrainS测试。本研究的数据来自402名参与者,其中217名(54.0%)完成了基线、6个月和12个月的评估(坚持参与者),185名(46%)只参加了基线测试,没有后续的web-LABrainS测试(退出参与者)。结果:我们的研究表明,即使参与者的外展和保留努力有限,使用自我指导、远程和基于网络的方法在社区居住的oa中进行纵向临床研究是可行的。与传统的临床纵向研究相比,web-LABrainS的退出在年龄、教育程度、性别、婚姻状况或独居方面没有观察到显著差异(P= 0.67, P= 0.67)。16日。29日。051年。31)。与传统的纵向研究类似,web-LABrainS的辍学者显著增加了抑郁症药物的使用,自我报告的行动能力下降,延迟回忆能力下降(P=.007,。007年,04)。有趣的是,在技术使用、技术舒适度、评估时间或同意就未来研究进行联系方面,坚持者和退出者之间没有观察到差异(P= 0.17, P= 0.17)。36岁。47岁的.40)。预测性二元逻辑回归得到了一个中等准确的模型,并进一步支持认知能力与辍学之间的负相关(OR 0.77, 95% CI 0.61-0.96)。结论:我们的研究为使用自我引导、远程和基于网络的方法进行纵向人体研究的可行性提供了一些初步的临床证据。此外,与传统的纵向研究形式相比,这些数据突出了使用这种方法与参与者退学相关的关键因素的异同。这项研究的发现可能有助于指导未来老年人纵向研究的设计和部署,这些研究主要集中在自我指导、远程或基于网络的方法上。
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引用次数: 0
Voice-Based Remote Care Program for Vulnerable Older Adults in a Rural Community: Single-Arm Pilot Clinical Study. 农村社区弱势老年人语音远程护理项目:单臂临床试验研究。
IF 4.8 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-11-13 DOI: 10.2196/76653
Geon Young Jang, Sunghwan Ji, Ji Yeon Baek, Eunju Lee, Seungryong Chong, Il-Young Jang

Background: Voice-based digital health technologies are highly feasible and acceptable tools for supporting older adults. However, their development has rarely focused on caregiving needs, and it is often poorly integrated with existing care services, thereby limiting their sustained effect.

Objective: This study aimed to evaluate the feasibility and effectiveness of a comprehensive voice-based remote care program developed in partnership with a local public health center.

Methods: A single-center, single-arm clinical study involving community-dwelling, socioeconomically vulnerable older adults was conducted using a Clinical Frailty Scale of 4-5. Participants received a 6-month voice-based care program comprising smart speaker daily check-ins, an emergency response system, and artificial intelligence-driven well-being check calls. These components were integrated with the public health center for continuous monitoring. The primary outcome was caregiver burden, assessed using the Korean version of the Zarit Burden Interview. Secondary outcomes include depression (Patient Health Questionnaire-9), anxiety (Generalized Anxiety Disorder-7), and quality of life (Korean version of the Control, Autonomy, Self-realization, and Pleasure scale).

Results: Among 100 enrolled participants, 96 (96%) completed the program. The caregiver burden slightly decreased from 17.1-16.2 points (mean difference -1, 95% CI -2.17 to 0.24; P=.12). However, caregivers reported a significant reduction in their perception of being the sole support provider (P=.003). Among older adults, significant improvements were observed in depression (Patient Health Questionnaire-9; P<.001), anxiety (Generalized Anxiety Disorder-7; P=.008), and quality of life (Korean version of the Control, Autonomy, Self-Realization, and Pleasure scale; P =.048).. Program adherence was high, with participants engaging for a median of 184 (IQR 154-203; 186/214, 87%) days.

Conclusions: Whereas the voice-based remote care program did not significantly reduce the overall caregiver burden, it significantly reduced the perception of the caregivers as being the sole support system. Furthermore, it influenced the psychological well-being of older adults by reducing depression and anxiety and enhancing their quality of life. High adherence and engagement enhance the feasibility and acceptability of scalable digital health interventions for vulnerable older adults in rural settings.

背景:基于语音的数字健康技术是支持老年人的高度可行和可接受的工具。然而,它们的发展很少侧重于护理需求,而且往往与现有护理服务结合不佳,从而限制了它们的持续效果。目的:本研究旨在评估与当地公共卫生中心合作开发的基于语音的综合远程护理计划的可行性和有效性。方法:采用临床虚弱量表4-5进行单中心、单臂临床研究,纳入社区居住、社会经济脆弱的老年人。参与者接受了为期6个月的语音护理计划,包括智能扬声器每日检查,紧急响应系统和人工智能驱动的健康检查电话。这些组成部分与公共卫生中心集成,以进行持续监测。主要结果是护理者负担,使用韩国版的Zarit负担访谈进行评估。次要结果包括抑郁(患者健康问卷-9)、焦虑(广泛性焦虑障碍-7)和生活质量(韩国版控制、自主、自我实现和快乐量表)。结果:在100名参与者中,96名(96%)完成了该计划。照顾者负担从17.1-16.2分略有下降(平均差值-1,95% CI -2.17至0.24;P= 0.12)。然而,照护者报告说,他们作为唯一支持提供者的感觉显著降低(P= 0.003)。结论:尽管基于语音的远程护理计划并没有显著减轻照顾者的整体负担,但它显著降低了照顾者作为唯一支持系统的感觉。此外,它还影响老年人的心理健康,减少抑郁和焦虑,提高他们的生活质量。高依从性和参与度提高了农村脆弱老年人可扩展数字卫生干预措施的可行性和可接受性。
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引用次数: 0
Associations Between Social Media Use and Anxiety and Depression Among Older Adults : Cross-Sectional Study. 社交媒体使用与老年人焦虑和抑郁之间的关系:横断面研究。
IF 4.8 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-11-10 DOI: 10.2196/71712
Jiaoling Huang, Zhenxing Ge, Yijing Chu, Yuge Yan, Wei Zhang, Hong Liang, Yuqi Yang, Hui Wang

Background: Social media engagement among older adults has surged worldwide, with China's older users exceeding 120 million in 2023. However, research remains disproportionately focused on youth. Critically, the dose-response relationship between use intensity and mental health in this population is poorly quantified, especially in rapidly aging societies such as China, where 23% of the population will be aged ≥65 years by 2035.

Objective: This study aimed to outline the social media use status among retired older adults and explore the association between social media use, including time spent on social media and social media addiction, and mental health status.

Methods: A cross-sectional survey was conducted in Shanghai, China, in 2024. A total of 15,986 retired participants were recruited via universities for older adults and primary health care institutions. Short versions of anxiety (the 2-item Generalized Anxiety Disorder scale) and depression (the 2-item Patient Health Questionnaire) scales were used to minimize the required time to complete the questionnaires for older adults. Logistic regressions were used to examine the associations between social media use and mental health after controlling for covariates. Subgroup analysis was conducted considering sex, age, marital status, urbanicity, and socioeconomic status.

Results: The participants had an average age of 68.49 (SD 7.6) years, with most (13,854/15,986, 86.7%) being married and living with their spouse and approximately half (8155/15,986, 51.0%) being male. Our research indicated that over 98% of retired older individuals (15,807/15,986, 98.88%) had used social media, with WeChat, Douyin, and Kuaishou being the most common platforms. Among them, 52.3% (8361/15,986) spent 2 to 3 hours a day on social media, 32.29% (5162/15,986) spent >4 hours a day, and 20.34% (3253/15,986) were addicted to social media. Older adults with ≥6 hours of daily social media use time exhibited higher rates of anxiety (odds ratio [OR] 1.44, 95% CI 1.20-1.72; P<.001) and depression (OR 1.50, 95% CI 1.25-1.79; P<.001) compared with those who used social media for ≤1 hour per day. Older adults addicted to social media had higher odds of anxiety (OR 2.81, 95% CI 2.57-3.08; P<.001) and depression (OR 2.51, 95% CI 2.30-2.75; P<.001). Subgroup analyses revealed stronger associations for women, people aged 49-75 years, those with a lower educational level and income, urban residents, and non-solo dwellers.

Conclusions: Retired older adults in Shanghai are an active group of social media users. Using social media for over 6 hours a day and social media addiction were significantly associated with anxiety and depression. Future social media research should pay more attention to older adults and explore these longitudinal relationships.

背景:全球老年人的社交媒体参与度激增,到2023年,中国老年用户将超过1.2亿。然而,研究仍然不成比例地集中在年轻人身上。至关重要的是,在这一人群中,使用强度与心理健康之间的剂量-反应关系没有得到很好的量化,特别是在快速老龄化的社会,如中国,到2035年,23%的人口将达到65岁以上。目的:本研究旨在概述退休老年人的社交媒体使用状况,并探讨社交媒体使用(包括社交媒体使用时间和社交媒体成瘾)与心理健康状况之间的关系。方法:于2024年在中国上海进行横断面调查。通过老年人大学和初级保健机构共招募了15 986名退休参与者。使用简短版本的焦虑(2项广泛性焦虑障碍量表)和抑郁(2项患者健康问卷)量表来减少老年人完成问卷所需的时间。在控制协变量后,使用逻辑回归来检验社交媒体使用与心理健康之间的关系。亚组分析考虑性别、年龄、婚姻状况、城市化程度和社会经济地位。结果:参与者的平均年龄为68.49岁(SD 7.6),大多数(13,854/15,986,86.7%)已婚并与配偶同住,约一半(8155/15,986,51.0%)为男性。我们的研究表明,超过98%的退休老年人(15,807/15,986,98.88%)使用过社交媒体,其中b微信、抖音和快手是最常见的平台。其中,52.3%(8361/ 15986)的人每天使用社交媒体的时间为2 - 3小时,32.29%(5162/ 15986)的人每天使用社交媒体的时间为10 - 4小时,20.34%(3253/ 15986)的人对社交媒体上瘾。每天使用社交媒体时间≥6小时的老年人表现出更高的焦虑率(比值比[OR] 1.44, 95% CI 1.20-1.72);结论:上海退休老年人是社交媒体用户的活跃群体。每天使用社交媒体超过6小时和社交媒体成瘾与焦虑和抑郁显著相关。未来的社交媒体研究应该更多地关注老年人,并探索这些纵向关系。
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引用次数: 0
Sleep Disturbance as a Catalyst in the Cyclical Link Between Depressive Symptoms and Disability in Instrumental Activities of Daily Living in Older Chinese Adults: Longitudinal Cohort Study. 睡眠障碍是中国老年人日常生活工具活动中抑郁症状与残疾之间周期性联系的催化剂:纵向队列研究
IF 4.8 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-11-06 DOI: 10.2196/76643
Hao Wu, Lu Wang, Xin Liu, Yuyue Yang, Wei Gao

Background: Depressive symptoms, sleep disturbances, and functional disability are interrelated. However, the bidirectional pathways between depression, sleep disturbances, and disability in instrumental activities of daily living (IADLs) remain underexplored in China.

Objective: We aimed to examine the bidirectional longitudinal relationships between depression and disability in IADLs among older Chinese adults, with a focus on elucidating the mediating role of sleep disturbances in this dynamic interplay.

Methods: The study encompassed 2677 older adults who provided complete data at T1 (2015), T2 (2018), and T3 (2020) for the China Health and Retirement Longitudinal Study (CHARLS). Depressive symptoms were assessed using the 10-item Center for Epidemiological Studies Depression (CESD-10) scale, and a 6-item scale was used to measure disability in IADLs. Sleep disturbances were self-reported. Temporal associations between depressive symptoms and disability in IADLs as well as the longitudinal mediating effect of sleep disturbances were examined using a cross-lagged panel model.

Results: Prior depression significantly predicted subsequent disability in IADLs at T2 (β=0.070, P<.001) and T3 (β=0.074, P<.001), and prior disability in IADL predicted subsequent depression at T2 (β=0.094, P<.001) and T3 (β=0.100, P<.001). Additionally, the indirect effect of prior disability in IADLs on subsequent depression via sleep disturbances was statistically significant (β=0.062, SE=0.010, P<.001), with the mediation effect accounting for 50.41% of the total effect. In contrast, after accounting for this mediation, the direct effect of prior depression on subsequent disability in IADLs was not significant (β=0.009, SE=0.018, P=.61). Consequently, the impact of depression on disability in IADLs was fully mediated through sleep disturbances in this cohort of older Chinese adults.

Conclusions: Depressive symptoms and disability in IADLs are bidirectionally linked, and sleep disturbances play a longitudinal mediating role in the bidirectional relationship among older Chinese adults. The potential longitudinal bidirectionality highlights the importance of sleep health for interventions on depression and functional disability in older adults.

背景:抑郁症状、睡眠障碍和功能障碍是相互关联的。然而,在中国,抑郁症、睡眠障碍和日常生活工具活动(IADLs)残疾之间的双向通路仍未得到充分探索。目的:研究中国老年人iadl中抑郁与残疾之间的双向纵向关系,重点阐明睡眠障碍在这种动态相互作用中的中介作用。方法:本研究纳入2677名老年人,他们在中国健康与退休纵向研究(CHARLS)的T1(2015)、T2(2018)和T3(2020)提供了完整的数据。采用流行病学研究中心抑郁(csd -10) 10项量表评估抑郁症状,并采用6项量表测量iadl中的残疾。睡眠障碍是自我报告的。使用交叉滞后面板模型检查了iadl中抑郁症状与残疾之间的时间关联以及睡眠障碍的纵向中介效应。结果:既往抑郁显著预测T2时iadl的残疾(β=0.070, p)。结论:中国老年人iadl的抑郁症状与残疾存在双向关联,睡眠障碍在双向关系中起纵向中介作用。潜在的纵向双向性强调了睡眠健康对老年人抑郁症和功能障碍干预的重要性。
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引用次数: 0
Aesthetic Experience in the Acceptance of Wearable Technology for People With Dementia: Critical Interpretive Synthesis. 痴呆症患者接受可穿戴技术的审美体验:批判性的解释性综合。
IF 4.8 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-11-06 DOI: 10.2196/72082
Yixuan Wei, John Ratcliffe, Dag Aarsland, Wei Liu

Background: The prevalence of dementia has led to a growing interest in wearable technologies to assist dementia care. Despite their potential, these technologies face low adoption rates, often attributed to poor aesthetic design and insufficient consideration of user experience.

Objective: This study aims to (1) explore how the aesthetic design of wearable devices relates to their adoption and user experience in dementia care and (2) critically examine the ways in which aesthetic elements shape people with dementia's perceptions of acceptability and inform future design considerations.

Methods: A critical interpretive synthesis with a systematic search was conducted across 2 databases, namely Web of Science and Scopus on August 22, 2024. Studies were included if they reported on the current use of wearable technologies in dementia care or provided value in qualitative studies addressing attitudes from people with dementia and their caregivers toward the wearable product. Two authors independently screened the abstracts and full texts to extract data, and additional studies were included from web searches, owing to their conceptual contributions to offering insights into the emergence of wearable technology, including the factors driving its commercial value and appraisal.

Results: A total of 63 studies were included in this study. Findings suggest that aesthetically considered designs are preferred by users when concerning their acceptance toward wearable devices, particularly when devices symbolize empowerment and support personal engagement. The objects that evoke comfort, emotional connection, and personal meaning are more likely to be accepted by people with dementia. Improved aesthetics may also support caregivers through more consistent and effective data collection.

Conclusions: This study uncovers a significant gap in the aesthetic design of wearable technologies for dementia care, limiting user acceptance and emotional engagement. By synthesizing key themes focusing on the interaction between user and product, this review proposes a conceptual framework for dementia care, emphasizing the importance of aesthetics in enabling more meaningful, inclusive, and human-centered design.

背景:痴呆症的流行导致人们对辅助痴呆症护理的可穿戴技术越来越感兴趣。尽管有潜力,但这些技术的采用率很低,通常归因于糟糕的美学设计和对用户体验的考虑不足。目的:本研究旨在(1)探索可穿戴设备的美学设计与痴呆症护理中的采用和用户体验之间的关系;(2)批判性地研究美学元素如何塑造痴呆症患者对可接受性的感知,并为未来的设计考虑提供信息。方法:于2024年8月22日对Web of Science和Scopus两个数据库进行系统检索,并进行批判性的解释性综合。如果研究报告了可穿戴技术在痴呆症护理中的当前使用情况,或者在定性研究中提供了价值,解决了痴呆症患者及其护理人员对可穿戴产品的态度,则将其纳入研究。两位作者独立筛选摘要和全文以提取数据,并从网络搜索中纳入其他研究,因为他们在概念上的贡献提供了对可穿戴技术出现的见解,包括推动其商业价值和评估的因素。结果:本研究共纳入63项研究。研究结果表明,当用户接受可穿戴设备时,尤其是当设备象征着授权和支持个人参与时,美学考虑的设计更受用户青睐。那些能唤起舒适感、情感联系和个人意义的物品更容易被痴呆症患者接受。改进的美学也可以通过更一致和有效的数据收集来支持护理人员。结论:本研究揭示了用于痴呆症护理的可穿戴技术的美学设计存在重大差距,限制了用户的接受度和情感参与。通过综合关注用户和产品之间交互的关键主题,本文提出了痴呆症护理的概念框架,强调美学在实现更有意义、包容性和以人为本的设计中的重要性。
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引用次数: 0
AI-Enhanced Multi-Algorithm R Shiny App for Predictive Modeling and Analytics: A Case study of Alzheimer's Disease Diagnostics. 用于预测建模和分析的ai增强多算法R Shiny应用程序:阿尔茨海默病诊断的案例研究。
IF 4.8 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-11-05 DOI: 10.2196/70272
Han Wenzheng, Edmund Fosu Agyemang, Sudesh Srivastav, Jeffrey Shaffer, Samuel Kakraba

Background: AI has demonstrated superior diagnostic accuracy compared to medical practitioners, highlighting its growing importance in healthcare. SMART-Pred (Shiny Multi-Algorithm R Tool for Predictive Modeling) is an innovative AI-based application for Alzheimer's disease (AD) prediction using handwriting analysis.

Objective: To develop and evaluate a non-invasive, cost-effective AI tool for early AD detection, addressing the need for accessible and accurate screening methods.

Methods: The study employed Principal Component Analysis (PCA) for dimensionality reduction of handwriting data, followed by training and evaluation of ten diverse AI models, including logistic regression, Naïve Bayes, random forest, AdaBoost, Support Vector Machine (SVM), and neural network. Model performance was assessed using accuracy, sensitivity, specificity, F1-score, and ROC-AUC metrics. The DARWIN dataset, comprising handwriting samples from 174 participants (89 AD patients, 85 healthy controls) was used for validation.

Results: The Neural Network classifier achieved an accuracy of 91% with a 95% CI ranging from 0.79-0.97 and an AUC of 94%, on the test set after identifying the most significant features for AD prediction. These results surpass current clinical diagnostic tools, which typically achieve around 81% accuracy. SMART-Pred's performance aligns with recent AI advancements in AD prediction, such as the Cambridge scientists' AI tool achieving 82% accuracy in identifying AD progression within three years using cognitive tests and MRI scans. The variables "air_time" and "paper_time" consistently emerged as critical predictors for AD across all ten AI models, highlighting their potential importance in early detection and risk assessment. To augment transparency and interpretability, we incorporated the principles of explainable AI, specifically using SHapley Additive exPlanations (SHAP) values, a state-of-the-art method to emphasize the features responsible for our model's efficacy.

Conclusions: SMART-Pred offers non-invasive, cost-effective, and efficient AD prediction, demonstrating the transformative potential of AI in healthcare. While clinical validation is necessary to confirm the practical applicability of the identified key variables, this study contributes to the growing body of research on AI-assisted AD diagnosis and may lead to improved patient outcomes through early detection and intervention.

Clinicaltrial:

背景:与医生相比,人工智能显示出更高的诊断准确性,凸显了其在医疗保健领域日益增长的重要性。SMART-Pred (Shiny多算法R工具预测建模)是一款基于人工智能的创新应用程序,用于使用手写分析预测阿尔茨海默病(AD)。目的:开发和评估用于早期AD检测的无创、经济高效的人工智能工具,满足对可获取和准确筛查方法的需求。方法:采用主成分分析(PCA)对手写数据进行降维,然后对logistic回归、Naïve贝叶斯、随机森林、AdaBoost、支持向量机(SVM)和神经网络等10种不同的人工智能模型进行训练和评价。使用准确性、敏感性、特异性、f1评分和ROC-AUC指标评估模型性能。DARWIN数据集包括174名参与者(89名AD患者,85名健康对照)的手写样本,用于验证。结果:在识别出最重要的AD预测特征后,神经网络分类器在测试集中实现了91%的准确率,95% CI范围为0.79-0.97,AUC为94%。这些结果超过了目前的临床诊断工具,通常达到81%左右的准确率。SMART-Pred的表现与最近人工智能在阿尔茨海默病预测方面的进展相一致,例如剑桥大学科学家的人工智能工具通过认知测试和核磁共振扫描,在三年内识别阿尔茨海默病进展的准确率达到82%。在所有10个人工智能模型中,变量“air_time”和“paper_time”一直是AD的关键预测因素,突出了它们在早期发现和风险评估中的潜在重要性。为了增加透明度和可解释性,我们结合了可解释人工智能的原则,特别是使用SHapley加性解释(SHAP)值,这是一种最先进的方法,以强调对我们模型的有效性负责的特征。结论:SMART-Pred提供无创、经济高效的AD预测,展示了人工智能在医疗保健领域的变革潜力。虽然需要临床验证来确认所确定的关键变量的实际适用性,但本研究有助于人工智能辅助AD诊断的研究,并可能通过早期发现和干预来改善患者的预后。临床试验:
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引用次数: 0
Impact of a Consumer e-Learning Course on Beliefs, Treatment Choices, and Outcomes Among People With Hip and Knee Osteoarthritis: Qualitative Interview Study. 消费者电子学习课程对髋关节和膝关节骨关节炎患者的信念、治疗选择和结果的影响:定性访谈研究。
IF 4.8 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-11-05 DOI: 10.2196/80282
Rachel K Nelligan, Libby Spiers, Rana S Hinman, Kim L Bennell

Background: First-line management for hip and knee osteoarthritis includes lifestyle treatments, such as exercise and weight loss (if appropriate), whereas joint replacement surgery is recommended only for severe symptoms after these options have been exhausted. However, many people with osteoarthritis hold misconceptions about the condition, leading to lower acceptance of nonsurgical treatments, such as exercise, and the mistaken belief that surgery is their only option. Novel patient education approaches that address these misconceptions are recommended to improve uptake of lifestyle treatments, reduce unnecessary surgery, and improve outcomes for people with osteoarthritis. We developed a 4-week self-directed consumer e-learning course on osteoarthritis management. In a randomized controlled trial, using the course led to immediate and sustained improvements in osteoarthritis knowledge. However, participants' perspectives on the course and an understanding of how it impacted osteoarthritis beliefs, treatment choices, and outcomes were unknown.

Objective: This study aims to explore how an e-learning course for people with hip and knee osteoarthritis may have impacted their osteoarthritis beliefs, treatment choices, and outcomes.

Methods: In this qualitative study, we conducted semistructured individual interviews (N=20) with randomized controlled trial participants with hip or knee osteoarthritis who accessed a 4-week consumer e-learning course on osteoarthritis and its management. Interviews were audio recorded, transcribed verbatim, and thematically analyzed following a framework approach, which was guided by the common sense model of self-regulation.

Results: Four themes were developed from the interviews: (1) participants reshaped their beliefs and attitudes toward osteoarthritis and its management, (2) participants adopted a proactive approach to management, (3) participants developed a more positive mindset, and (4) the course supported learning and shifts in beliefs.

Conclusions: The e-learning course resulted in shifts in participants' beliefs and attitudes toward osteoarthritis and its management, increasing their confidence in living with osteoarthritis and resulting in a more optimistic outlook on the future. The e-learning course is freely available and could be a useful resource for people with osteoarthritis to enhance their understanding of the condition and its management.

背景:髋关节和膝关节骨性关节炎的一线治疗包括生活方式治疗,如运动和减肥(如果合适),而关节置换手术只推荐在这些治疗方法已经失效后出现严重症状的患者。然而,许多患有骨关节炎的人对这种疾病有误解,导致不太接受非手术治疗,比如运动,并且错误地认为手术是他们唯一的选择。建议采用新颖的患者教育方法解决这些误解,以提高对生活方式治疗的接受程度,减少不必要的手术,并改善骨关节炎患者的预后。我们开发了一个为期4周的自我指导的消费者骨关节炎管理电子学习课程。在一项随机对照试验中,使用该课程导致骨关节炎知识的即时和持续改善。然而,参与者对过程的看法以及对它如何影响骨关节炎信念、治疗选择和结果的理解尚不清楚。目的:本研究旨在探讨髋关节和膝关节骨关节炎患者的电子学习课程如何影响他们对骨关节炎的信念、治疗选择和结果。方法:在这项定性研究中,我们对髋关节或膝关节骨关节炎的随机对照试验参与者进行了半结构化的个人访谈(N=20),这些参与者参加了为期4周的骨关节炎及其管理消费者电子学习课程。访谈录音,逐字转录,并按照框架方法进行主题分析,该框架方法以自我调节的常识模型为指导。结果:从访谈中得出四个主题:(1)参与者重塑了他们对骨关节炎及其治疗的信念和态度;(2)参与者采取了积极主动的管理方法;(3)参与者形成了更积极的心态;(4)课程支持学习和信念转变。结论:在线学习课程改变了参与者对骨关节炎及其治疗的信念和态度,增加了他们与骨关节炎生活的信心,并使他们对未来的看法更加乐观。该在线学习课程是免费提供的,可以为骨关节炎患者提供有用的资源,以提高他们对病情及其管理的理解。
{"title":"Impact of a Consumer e-Learning Course on Beliefs, Treatment Choices, and Outcomes Among People With Hip and Knee Osteoarthritis: Qualitative Interview Study.","authors":"Rachel K Nelligan, Libby Spiers, Rana S Hinman, Kim L Bennell","doi":"10.2196/80282","DOIUrl":"10.2196/80282","url":null,"abstract":"<p><strong>Background: </strong>First-line management for hip and knee osteoarthritis includes lifestyle treatments, such as exercise and weight loss (if appropriate), whereas joint replacement surgery is recommended only for severe symptoms after these options have been exhausted. However, many people with osteoarthritis hold misconceptions about the condition, leading to lower acceptance of nonsurgical treatments, such as exercise, and the mistaken belief that surgery is their only option. Novel patient education approaches that address these misconceptions are recommended to improve uptake of lifestyle treatments, reduce unnecessary surgery, and improve outcomes for people with osteoarthritis. We developed a 4-week self-directed consumer e-learning course on osteoarthritis management. In a randomized controlled trial, using the course led to immediate and sustained improvements in osteoarthritis knowledge. However, participants' perspectives on the course and an understanding of how it impacted osteoarthritis beliefs, treatment choices, and outcomes were unknown.</p><p><strong>Objective: </strong>This study aims to explore how an e-learning course for people with hip and knee osteoarthritis may have impacted their osteoarthritis beliefs, treatment choices, and outcomes.</p><p><strong>Methods: </strong>In this qualitative study, we conducted semistructured individual interviews (N=20) with randomized controlled trial participants with hip or knee osteoarthritis who accessed a 4-week consumer e-learning course on osteoarthritis and its management. Interviews were audio recorded, transcribed verbatim, and thematically analyzed following a framework approach, which was guided by the common sense model of self-regulation.</p><p><strong>Results: </strong>Four themes were developed from the interviews: (1) participants reshaped their beliefs and attitudes toward osteoarthritis and its management, (2) participants adopted a proactive approach to management, (3) participants developed a more positive mindset, and (4) the course supported learning and shifts in beliefs.</p><p><strong>Conclusions: </strong>The e-learning course resulted in shifts in participants' beliefs and attitudes toward osteoarthritis and its management, increasing their confidence in living with osteoarthritis and resulting in a more optimistic outlook on the future. The e-learning course is freely available and could be a useful resource for people with osteoarthritis to enhance their understanding of the condition and its management.</p>","PeriodicalId":36245,"journal":{"name":"JMIR Aging","volume":"8 ","pages":"e80282"},"PeriodicalIF":4.8,"publicationDate":"2025-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12631089/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145453377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Double-Edged Sword of Digital Engagement-How Digital Access and Internet Use Reshape Sleep Schedules and Underlying Mechanisms in Older Adults: Longitudinal Observational Study. 数字参与的双刃剑——数字访问和互联网使用如何重塑老年人的睡眠时间表和潜在机制:纵向观察研究。
IF 4.8 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-11-05 DOI: 10.2196/79731
Chi Zhang, Longxuan Lin, Li Wang, Han Hu, Heyang Zhang
<p><strong>Background: </strong>Given the rapid development of the digital economy and the sustained proliferation of the internet, digital engagement in older adults has garnered mounting attention from the academic community. However, research has yet to systematically examine the impact of digital engagement on sleep in this demographic.</p><p><strong>Objective: </strong>This study aims to examine the association of digital engagement-operationalized as digital access and internet use duration-with the sleep schedules (nocturnal sleep duration, afternoon nap duration, and sleep onset time) of older adults in China, using longitudinal data and robust statistical modeling to explore longitudinal associations and potential mechanisms.</p><p><strong>Methods: </strong>Data were derived from 4 waves (2014, 2016, 2018, and 2020) of the China Family Panel Studies, involving 16,784 older adults (≥60 y). We used panel fixed effects models and a random-effects ordered logit model to analyze the effects on continuous outcomes (nocturnal and nap sleep duration), controlling for time-invariant individual characteristics. As sleep onset time is an ordinal variable, a random-effects ordered logit model was used for this outcome. Moderation analyses were conducted by introducing interaction terms (digital engagement×sex and digital engagement×residence) into the models to examine heterogeneity across subgroups (urban or rural, men or women). Mediation analyses were performed using the Sobel test with year-fixed effects and the nonparametric bootstrap method (1000 resamples) to assess the significance of indirect effects via mechanistic pathways (nonfarm employment, protein intake, memory, depressive mood, and instrumental activities of daily living).</p><p><strong>Results: </strong>The study included a total of 16,784 older adults, with an average age of 69 (SE 6.946) years, including 9100 (54.22%) women and 7684 (45.78%) men. The results showed that both digital access (β=-.15, 95% CI -.25 to -.06; P=.002) and internet use time (β=-.07, 95% CI -.13 to -.01; P=.027) were significantly associated with significantly shorter sleep duration of older adults. Digital access was significantly associated with a significant reduction in the length of afternoon naps among older adults, while internet use did not have this effect; both digital access and internet use were significantly associated with a significant delay in older adults' sleep onset time. Digital access was associated with older adults' sleep schedules through its correlations with nonfarm employment, protein intake, memory, depressive mood, and instrumental activities of daily living. Digital access had a greater and more significant impact on men and urban older adults, while internet use had a greater and more significant impact on women and urban older adults.</p><p><strong>Conclusions: </strong>The study indicates that digital engagement, such as the use of electronic devices, is associated with a r
背景:随着数字经济的快速发展和互联网的持续扩散,老年人的数字参与已经引起了学术界越来越多的关注。然而,目前还没有研究系统地调查数字参与对这一人群睡眠的影响。目的:本研究旨在通过纵向数据和稳健统计模型探讨中国老年人数字参与(具体为数字访问和互联网使用时长)与睡眠时间(夜间睡眠时间、午睡时间和睡眠开始时间)之间的关联及其潜在机制。方法:数据来自中国家庭小组研究的4波(2014年、2016年、2018年和2020年),涉及16784名年龄≥60岁的老年人。我们使用面板固定效应模型和随机效应有序logit模型来分析对连续结果(夜间和午睡睡眠时间)的影响,控制时不变的个体特征。由于睡眠开始时间是一个有序变量,因此对该结果使用了随机效应有序logit模型。通过在模型中引入交互术语(数字engagement×sex和数字engagement×residence)来进行适度分析,以检查亚组(城市或农村,男性或女性)的异质性。采用具有年固定效应的Sobel检验和非参数自举法(1000个样本)进行中介分析,以评估通过机械途径(非农就业、蛋白质摄入、记忆、抑郁情绪和日常生活工具活动)产生的间接影响的重要性。结果:共纳入老年人16784例,平均年龄69岁(SE 6.946),其中女性9100例(54.22%),男性7684例(45.78%)。结果显示,数字访问(β=- 0.15, 95% CI - 0.25 ~ - 0.06; P= 0.002)和互联网使用时间(β=- 0.07, 95% CI - 0.13 ~ - 0.01; P= 0.027)与老年人睡眠时间显著缩短相关。在老年人中,数字设备的使用与午睡时间的显著减少有显著的关系,而互联网的使用则没有这种影响;数字访问和互联网使用与老年人睡眠开始时间的显著延迟显著相关。通过与非农业就业、蛋白质摄入、记忆、抑郁情绪和日常生活工具活动的相关性,数字访问与老年人的睡眠时间表相关。数字访问对男性和城市老年人的影响越来越大,而互联网使用对女性和城市老年人的影响越来越大。结论:该研究表明,在老年人中,电子设备的使用等数字参与与日常和午睡睡眠时间的减少以及睡眠开始的延迟有关。
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引用次数: 0
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JMIR Aging
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