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Home-Based Exercise and Fall Prevention in Older Adults: Development, Validation and Usability of the Mais Equilíbrio Mobile App. 老年人家庭运动和跌倒预防:Mais Equilíbrio移动应用程序的开发、验证和可用性。
IF 4.8 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-11-04 DOI: 10.2196/80724
Mateus Medeiros Leite, Alessandro de Oliveira Silva, Silvana Schwerz Funghetto, Luciano Ramos de Lima, Samuel Barbosa Mezavila Abdelmur, Hudson Azevedo Pinheiro, Calliandra Maria de Souza Silva, Maurílio Tiradentes Dutra, Marina Morato Stival

Background: The global aging population and the high incidence of falls among this population highlight the need for effective preventive strategies. Home-based exercise programs, such as the Otago protocol, have demonstrated efficacy in reducing fall risk but often face barriers related to user adherence. Mobile health (mHealth) apps offer promising tools to support health promotion and enhance autonomy in older adults.

Objective: This study aims to develop and validate a prototype mobile app, Mais Equilíbrio (More Balance), designed to guide older adults in performing home-based physical exercises adapted from the Otago protocol.

Methods: This methodological study was conducted in two phases: (1) content validation by 22 experts in physical education and physiotherapy using the Suitability Assessment of Materials (SAM) scale, and (2) usability testing with 24 older adults (aged 60 to 80 y), using the System Usability Scale (SUS). An overall score above 70% on the SAM and above 85 on the SUS were considered indicators of high quality and excellent usability, respectively.

Results: The Mais Equilíbrio (More Balance) app was developed based on the Otago protocol and tailored for independent home use. A Content Validity Index above 0.95 was observed for all items. An overall average score of 81.20 (SD 15.78) on the SAM scale was found, classifying the material as "superior." Usability tests with older adults showed an average score of 95.98 (SD 5.58) on the SUS, indicating excellent usability. The highest scores were observed in "ease of use" and "user confidence."

Conclusions: The Mais Equilíbrio (More Balance) app, distinct for digitally adapting the Otago protocol to the Brazilian context and for its dual validation process with experts and older adults, has proven to be a valid and highly usable tool for guiding home-based physical exercise in older adults, with potential to promote fall prevention and autonomy.

背景:全球人口老龄化和高发的跌倒在这一人口突出需要有效的预防策略。以家庭为基础的锻炼项目,如奥塔哥协议,已经证明在降低跌倒风险方面有效,但往往面临与用户坚持相关的障碍。移动健康(mHealth)应用程序为支持健康促进和增强老年人的自主性提供了有前途的工具。目的:本研究旨在开发和验证一个原型移动应用程序Mais Equilíbrio (More Balance),旨在指导老年人进行根据奥塔哥协议改编的家庭体育锻炼。方法:本方法学研究分两个阶段进行:(1)由22名体育和理疗专家使用材料适用性评估量表(SAM)进行内容验证;(2)使用系统可用性量表(SUS)对24名老年人(60至80岁)进行可用性测试。SAM总分超过70%,SUS总分超过85分,分别被认为是高质量和优秀可用性的指标。结果:Mais Equilíbrio (More Balance)应用程序是基于奥塔哥协议开发的,适合独立家庭使用。所有项目的内容效度指数均在0.95以上。在SAM量表上的总体平均得分为81.20(标准差15.78),将材料分类为“优秀”。对老年人的可用性测试显示,SUS的平均得分为95.98 (SD 5.58),表明可用性很好。得分最高的是“易用性”和“用户信心”。结论:Mais Equilíbrio (More Balance)应用程序的独特之处在于将奥塔哥协议数字化地适应巴西的环境,并通过专家和老年人的双重验证过程,已被证明是指导老年人在家进行体育锻炼的有效且高度可用的工具,具有促进跌倒预防和自主的潜力。
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引用次数: 0
Development and Validation of the Healthy Longevity Index for Personalized Healthy Aging in Primary Care: Cross-National Retrospective Analysis. 初级保健中个性化健康老龄化健康寿命指数的制定与验证:跨国回顾性分析。
IF 4.8 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-11-03 DOI: 10.2196/80034
Hsi-Yu Lai, Shu Zhang, Rei Otsuka, Shih-Tsung Huang, Hidenori Arai, Fei-Yuan Hsiao, Liang-Kung Chen

Background: Measuring and promoting healthy aging at an individual level remains challenging as promoting healthy longevity requires real-time, personalized tools to assess risk and guide interventions in clinical practice.

Objective: This study aimed to develop and validate a novel Healthy Longevity Index (HLI) for use in primary care settings in older adults.

Methods: Using data from the Taiwan Longitudinal Study on Aging (TLSA; n=4470), we developed a nomogram-based HLI incorporating demographics, lifestyle factors, intrinsic capacity (IC) measures, and chronic conditions to predict 4-, 8-, and 12-year disability- and dementia-free survival (absence of physical disability, dementia, or mortality). The HLI was internally validated in a TLSA subset and externally validated in the Japanese National Institute for Longevity Sciences, Longitudinal Study of Aging (NILS-LSA) cohort (n=1090).

Results: The 12-year HLI nomogram demonstrated robust performance, with C-statistics of 0.79 (bootstrapped 95% CI 0.78-0.80) in the TLSA training cohort and 0.77 (bootstrapped 95% CI 0.75-0.79) in the TLSA validation cohort. External validation in the NILS-LSA yielded a C-statistic of 0.71 (bootstrapped 95% CI 0.66-0.76). The HLI effectively stratified participants into risk tertiles, with the highest-risk group showing only 27.8% probability of 12-year disability- and dementia-free survival compared to 87.8% in the lowest-risk group. Key predictors included age, sex, education, and, particularly, IC impairments in locomotion, visual acuity, and cognition-all assessable during routine primary care consultations.

Conclusions: The HLI provides a practical tool for real-time, personalized assessment of healthy longevity risk in primary care settings. Its design enables providers to deliver person-centered care through targeted interventions and individualized prevention strategies that promote healthy aging across populations, especially in older adults.

背景:在个人层面衡量和促进健康老龄化仍然具有挑战性,因为促进健康长寿需要实时、个性化的工具来评估风险并指导临床实践中的干预措施。目的:本研究旨在开发和验证一种用于老年人初级保健机构的新型健康寿命指数(HLI)。方法:使用台湾老龄化纵向研究(TLSA; n=4470)的数据,我们开发了一个基于nomogram HLI,包括人口统计学、生活方式因素、内在能力(IC)测量和慢性疾病,以预测4年、8年和12年的无残疾和无痴呆生存(无身体残疾、痴呆或死亡)。HLI在TLSA子集中进行了内部验证,在日本国家长寿科学研究所老龄化纵向研究(NILS-LSA)队列中进行了外部验证(n=1090)。结果:12年HLI nomogram显示了稳健的表现,在TLSA训练队列中,c统计量为0.79(自举95% CI为0.78-0.80),在TLSA验证队列中,c统计量为0.77(自举95% CI为0.75-0.79)。NILS-LSA的外部验证的c统计量为0.71(自举95% CI 0.66-0.76)。HLI有效地将参与者分层为风险各组,风险最高的组显示12年无残疾和痴呆生存的概率只有27.8%,而风险最低的组为87.8%。关键的预测因素包括年龄、性别、教育程度,尤其是运动、视力和认知方面的IC损伤——所有这些都可以在常规初级保健咨询中评估。结论:HLI为初级保健机构的健康长寿风险提供了实时、个性化评估的实用工具。它的设计使提供者能够通过有针对性的干预措施和个性化的预防策略来提供以人为本的护理,促进整个人群,特别是老年人的健康老龄化。
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引用次数: 0
The Caregiver Support Model for Informal Caregivers of Frail Older Adults: Randomized Controlled Trial. 体弱老年人非正式照顾者的照顾者支持模型:随机对照试验。
IF 4.8 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-11-03 DOI: 10.2196/71638
Cyrus Lap Kwan Leung, Kin-Kit Li, Dannii Y Yeung, Alice Ming Lin Chong, Marcus Yu Lung Chiu, Xin Guan, Tit Wing Lo

Background: Caregivers of frail older adults face substantial challenges, often managing their own health while providing care. To address these issues, we developed the caregiver support model (CSM), a structured approach that uses systematic assessment, personalized intervention planning, and sustained support to address informal family caregivers' diverse and evolving needs and leverage their resources.

Objective: This study aims to evaluate the effectiveness of CSM.

Methods: A blinded cluster randomized controlled trial was conducted across 8 centers providing services for older adults in Hong Kong. The CSM is a social worker-guided intervention that integrates a structured assessment of caregiver needs and resources, personalized service planning, and ongoing monitoring over 6 months. Meanwhile, the control group continued with their usual procedures without a standardized caregiver assessment. Data were collected at baseline, 3 months, and 6 months.

Results: We recruited 565 informal family caregivers (281/565, 49.7% CSM intervention; 284/565, 50.3% standard care control). Both groups improved over time; compared with the control group, the CSM produced greater reductions in caregiver needs, particularly in role conflict, and greater gains in resources, such as health awareness. Improvements were more pronounced at 6 months compared to 3 months, indicating a lasting effect and consolidation of gains. The intervention was particularly effective for caregivers in other relationships (not spouse or child) and those with higher education than spousal caregivers.

Conclusions: These findings highlight the importance of long-term tailored interventions that adapt to the evolving needs of caregivers through systematic assessment. The CSM offers a promising approach to enhancing the well-being of caregivers and managing the complex demands of caregiving, particularly in an aging population.

背景:体弱老年人的照顾者面临着巨大的挑战,往往在提供护理的同时管理自己的健康。为了解决这些问题,我们开发了照顾者支持模型(CSM),这是一种结构化的方法,使用系统评估、个性化干预计划和持续支持来解决非正式家庭照顾者多样化和不断变化的需求,并利用他们的资源。目的:评价CSM的治疗效果。方法:在香港8个老年人服务中心进行盲法整群随机对照试验。CSM是一种由社会工作者指导的干预,它整合了对照顾者需求和资源的结构化评估、个性化服务计划和持续监测超过6个月。与此同时,对照组继续他们的常规程序,没有标准化的照顾者评估。在基线、3个月和6个月时收集数据。结果:共招募非正规家庭照顾者565人(28.1 /565,49.7% CSM干预组;28.4 /565,50.3%标准护理对照组)。随着时间的推移,两组都有所改善;与对照组相比,CSM在照顾者需求(尤其是角色冲突)方面产生了更大的减少,并在资源(如健康意识)方面获得了更大的收益。与3个月相比,6个月的改善更为明显,表明效果持久且巩固了收益。干预对其他关系中的照顾者(不是配偶或子女)和比配偶照顾者受教育程度更高的照顾者特别有效。结论:这些发现强调了通过系统评估适应护理人员不断变化的需求的长期量身定制干预措施的重要性。CSM提供了一个有希望的方法来提高照顾者的福祉和管理照顾的复杂需求,特别是在老龄化人口。
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引用次数: 0
Effectiveness of mHealth-Based Gamified Interventions on Physical Activity in Older Adults: Systematic Review. 基于移动健康的游戏化干预对老年人身体活动的有效性:系统评价。
IF 4.8 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-10-31 DOI: 10.2196/78686
Lin Chen, Fenglin Jang, Min Li, Wei Zong, Huiqin Yu

Background: Global aging presents significant socioeconomic and health challenges, particularly for older adults who face an increased risk of chronic diseases and reduced physical activity levels. Although physical activity is crucial for maintaining health, most older adults do not meet the recommended guidelines. Gamification and mobile health (mHealth) technologies offer innovative solutions to motivate physical activity; however, research focusing on older adults is limited, especially regarding the effectiveness and sustainability of such interventions.

Objective: This study aims to synthesize evidence on the effectiveness of mHealth-based gamified interventions for improving physical activity in older adults.

Methods: This systematic review followed Preferred Reporting Items for Systematic Reviews and Meta-Analyses and Meta-Analysis of Observational Studies in Epidemiology guidelines and analyzed studies from PubMed, Embase, Web of Science, CINAHL, Scopus, and Wiley Online Library, covering relevant literature from their inception up to May 2025. The inclusion criteria focused on gamified mHealth interventions for adults aged 60+ years, excluding serious games. Quality assessment was conducted according to the Joanna Briggs Institute standards, with data extracted on study design, gamification elements, and outcomes such as step counts and moderate-to-vigorous physical activity.

Results: Of 2944 studies identified from the database search, 1454 individuals from 8 trials were included. Gamified interventions significantly increased daily step counts and time spent in moderate-to-vigorous physical activity among older adults. Goal setting and rewards were the most frequently used components, and the combined use of mobile and wearable devices offered greater flexibility and accessibility. A classification framework indicated that interventions integrating multiple gamification elements with hybrid technology systems were most effective, particularly when guided by a theoretical basis. However, the heterogeneity in study designs, small sample sizes, and lack of long-term follow-up studies limited the generalizability of the findings.

Conclusions: mHealth-based gamification interventions demonstrate potential for increasing physical activity in older adults. Future interventions should consider employing multifaceted designs combining advanced gamification with hybrid technology systems, while also prioritizing theoretical integration, long-term sustainability, and caregiver involvement to improve sustainability and inclusivity. This review highlights the need for theory-driven, technology-mediated strategies that address the unique health needs of older adults.

背景:全球老龄化带来了重大的社会经济和健康挑战,特别是对于面临慢性病风险增加和身体活动水平降低的老年人。虽然体育活动对保持健康至关重要,但大多数老年人都没有达到建议的指导方针。游戏化和移动健康(mHealth)技术提供了创新的解决方案,以激励身体活动;然而,针对老年人的研究是有限的,特别是关于这些干预措施的有效性和可持续性。目的:本研究旨在综合基于移动健康的游戏化干预对改善老年人身体活动的有效性的证据。方法:本系统评价遵循流行病学指南中系统评价和观察性研究的荟萃分析和荟萃分析的首选报告项目,并分析了PubMed, Embase, Web of Science, CINAHL, Scopus和Wiley Online Library的研究,涵盖了从成立到2025年5月的相关文献。纳入标准侧重于针对60岁以上成年人的游戏化移动健康干预措施,不包括严肃游戏。质量评估是根据乔安娜布里格斯研究所的标准进行的,提取的数据包括研究设计、游戏化元素以及步数和中高强度体育锻炼等结果。结果:从数据库检索中确定的2944项研究中,包括来自8项试验的1454名个体。游戏化干预显着增加了老年人的每日步数和花在中等到剧烈体育活动上的时间。目标设定和奖励是最常用的组件,移动和可穿戴设备的结合使用提供了更大的灵活性和可访问性。分类框架表明,将多种游戏化元素与混合技术系统相结合的干预措施最为有效,特别是在理论基础的指导下。然而,研究设计的异质性、小样本量和缺乏长期随访研究限制了研究结果的普遍性。结论:基于移动健康的游戏化干预显示了增加老年人身体活动的潜力。未来的干预措施应考虑采用多方面的设计,将先进的游戏化与混合技术系统相结合,同时优先考虑理论整合、长期可持续性和护理人员参与,以提高可持续性和包容性。本综述强调需要理论驱动、技术介导的策略来解决老年人独特的健康需求。
{"title":"Effectiveness of mHealth-Based Gamified Interventions on Physical Activity in Older Adults: Systematic Review.","authors":"Lin Chen, Fenglin Jang, Min Li, Wei Zong, Huiqin Yu","doi":"10.2196/78686","DOIUrl":"10.2196/78686","url":null,"abstract":"<p><strong>Background: </strong>Global aging presents significant socioeconomic and health challenges, particularly for older adults who face an increased risk of chronic diseases and reduced physical activity levels. Although physical activity is crucial for maintaining health, most older adults do not meet the recommended guidelines. Gamification and mobile health (mHealth) technologies offer innovative solutions to motivate physical activity; however, research focusing on older adults is limited, especially regarding the effectiveness and sustainability of such interventions.</p><p><strong>Objective: </strong>This study aims to synthesize evidence on the effectiveness of mHealth-based gamified interventions for improving physical activity in older adults.</p><p><strong>Methods: </strong>This systematic review followed Preferred Reporting Items for Systematic Reviews and Meta-Analyses and Meta-Analysis of Observational Studies in Epidemiology guidelines and analyzed studies from PubMed, Embase, Web of Science, CINAHL, Scopus, and Wiley Online Library, covering relevant literature from their inception up to May 2025. The inclusion criteria focused on gamified mHealth interventions for adults aged 60+ years, excluding serious games. Quality assessment was conducted according to the Joanna Briggs Institute standards, with data extracted on study design, gamification elements, and outcomes such as step counts and moderate-to-vigorous physical activity.</p><p><strong>Results: </strong>Of 2944 studies identified from the database search, 1454 individuals from 8 trials were included. Gamified interventions significantly increased daily step counts and time spent in moderate-to-vigorous physical activity among older adults. Goal setting and rewards were the most frequently used components, and the combined use of mobile and wearable devices offered greater flexibility and accessibility. A classification framework indicated that interventions integrating multiple gamification elements with hybrid technology systems were most effective, particularly when guided by a theoretical basis. However, the heterogeneity in study designs, small sample sizes, and lack of long-term follow-up studies limited the generalizability of the findings.</p><p><strong>Conclusions: </strong>mHealth-based gamification interventions demonstrate potential for increasing physical activity in older adults. Future interventions should consider employing multifaceted designs combining advanced gamification with hybrid technology systems, while also prioritizing theoretical integration, long-term sustainability, and caregiver involvement to improve sustainability and inclusivity. This review highlights the need for theory-driven, technology-mediated strategies that address the unique health needs of older adults.</p>","PeriodicalId":36245,"journal":{"name":"JMIR Aging","volume":"8 ","pages":"e78686"},"PeriodicalIF":4.8,"publicationDate":"2025-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12577663/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145423202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Examining Technology Perspectives of Older Adults With Mild Cognitive Impairment: Scoping Review. 研究轻度认知障碍老年人的技术观点:范围回顾。
IF 4.8 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-10-30 DOI: 10.2196/78229
Snezna Bizilj Schmidt, Stephen Isbel, Blooma John, Ramanathan Subramanian, Nathan Martin D'Cunha
<p><strong>Background: </strong>Mild cognitive impairment (MCI) affects up to 20% of people older than the age of 65 years. The global incidence of MCI is increasing, and technology is being explored for early intervention. Theories of technology adoption predict that useful and easy-to-use solutions will have higher rates of adoption; however, these models do not specifically consider older adults with cognitive impairments or the unique human-computer interaction challenges posed by MCI. There are gaps in understanding the combined impacts of aging and cognitive impairment on factors affecting technology adoption for older adults with MCI, and it is not clear how MCI impacts human-computer interaction and device and interaction modality preferences in this population.</p><p><strong>Objective: </strong>This study aimed to collate perspectives from older adults with MCI about technology solutions proposed for them, to understand whether solutions are perceived as useful, easy to use, and what changes are suggested. It also identifies which devices and interaction modalities are preferred, and other factors that may affect usage and adoption.</p><p><strong>Methods: </strong>This scoping review was completed according to the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews) guidelines. A consistent search was performed across 9 electronic databases (ACM Digital Library, EBSCOhost CINAHL Plus with Full Text, EBSCOhost Computers and Applied Sciences Complete, Google Scholar, JMIR Publications, IEEE Xplore, EBSCOhost MEDLINE, Scopus, and Web of Science Core Collection) for studies published between January 1, 2014, and May 1, 2024. Extracted data were analyzed using inductive thematic analysis.</p><p><strong>Results: </strong>We identified 4271 studies, and after the removal of duplicates and screening, 83 studies were included for data extraction. Inductive thematic analysis of feedback from older adults with MCI about technology solutions proposed for them identified five themes: (1) purpose and need, (2) solution design and ease of use, (3) self-impression, (4) lifestyle, and (5) interaction modality. Solutions were perceived as useful, even though gaps in functional support exist; however, they were not perceived as entirely easy to use due to issues related to usability and user experience. Devices that are lightweight, portable, familiar, and have large screens are preferred, as is multimodal interaction-particularly speech, visual or text, and touch.</p><p><strong>Conclusions: </strong>Using technology can create feelings that positively or negatively affect a user's comfort, confidence, and overall well-being. Older adults with MCI value independence and autonomy, and solution designs should support these. Usefulness, ease of use, security, privacy, cost, physical comfort, and convenience are important considerations for technology use. Reliable technology creates trust, confidence, a
背景:轻度认知障碍(MCI)影响多达20%的65岁以上老年人。全球轻度认知障碍的发病率正在上升,人们正在探索早期干预的技术。技术采用理论预测,有用和易于使用的解决方案将有更高的采用率;然而,这些模型并没有特别考虑到有认知障碍的老年人或MCI带来的独特的人机交互挑战。对于老年MCI患者,年龄和认知障碍对影响技术采用因素的综合影响的理解存在空白,MCI如何影响该人群的人机交互以及设备和交互方式偏好尚不清楚。目的:本研究旨在整理老年MCI患者对技术解决方案的看法,以了解解决方案是否被认为是有用的,易于使用的,以及建议进行哪些改变。它还确定了首选的设备和交互模式,以及可能影响使用和采用的其他因素。方法:根据PRISMA-ScR(系统评价和荟萃分析扩展范围评价的首选报告项目)指南完成范围评价。对2014年1月1日至2024年5月1日之间发表的9个电子数据库(ACM Digital Library, EBSCOhost CINAHL Plus with全文,EBSCOhost Computers and Applied Sciences Complete, b谷歌Scholar, JMIR Publications, IEEE Xplore, EBSCOhost MEDLINE, Scopus和Web of Science Core Collection)进行了一致的搜索。提取的数据采用归纳主题分析法进行分析。结果:我们确定了4271项研究,在去除重复和筛选后,纳入了83项研究进行数据提取。对老年MCI患者关于技术解决方案的反馈进行归纳主题分析,确定了五个主题:(1)目的和需求,(2)解决方案设计和易用性,(3)自我印象,(4)生活方式,(5)交互方式。解决方案被认为是有用的,即使在功能支持方面存在差距;然而,由于与可用性和用户体验相关的问题,它们并不被认为完全容易使用。轻便、便携、熟悉、大屏幕的设备是首选,多模式交互——尤其是语音、视觉或文本以及触摸——也是首选。结论:使用技术可以产生积极或消极的感觉,影响用户的舒适度、信心和整体幸福感。患有轻度认知障碍的老年人重视独立性和自主性,解决方案设计应支持这些。实用性、易用性、安全性、隐私性、成本、物理舒适性和便利性是技术使用的重要考虑因素。可靠的技术创造信任、信心和授权感。这篇综述建议未来的工作(1)提高可用性和用户体验,(2)增强个性化,(3)更好地了解交互偏好和有效性,(4)启用多模式交互选项,(5)更无缝地将解决方案集成到用户的生活方式中。
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引用次数: 0
Correction: Machine Learning Approach for Frailty Detection in Long-Term Care Using Accelerometer-Measured Gait and Daily Physical Activity: Model Development and Validation Study. 修正:使用加速度计测量的步态和日常身体活动进行长期护理中虚弱检测的机器学习方法:模型开发和验证研究。
IF 4.8 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-10-29 DOI: 10.2196/85173
Xiaoping Zheng, Ziwei Zeng, Kimberley S van Schooten, Yijian Yang

[This corrects the article DOI: 10.2196/77140.].

[更正文章DOI: 10.2196/77140]。
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引用次数: 0
Free-Text Responses in a Nationally Representative Experimental Survey about End-of-Life Care Choices: ChatGPT-4o-Assisted Qualitative Analytical Study. 关于临终关怀选择的全国性代表性实验调查中的自由文本反应:chatgpt - 40辅助定性分析研究。
IF 4.8 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-10-29 DOI: 10.2196/76335
Elizabeth M Goldberg, Mario Macis, Megan Bounds, Jonathan Gomez Picazo, Lauren Hersch Nicholas

Background: Little is known about how surrogates make end-of-life care choices for patients who lack the ability to make decisions for themselves.

Objective: The study aims (1) to identify key themes that emerged from participants' free-text responses to a large nationally representative vignette survey about surrogate decision-making in end-of-life care and (2) to determine if an advanced artificial intelligence (AI) chatbot could assist us in accurately and efficiently performing qualitative analyses.

Methods: Our dataset included 3931 free-text responses from a nationally representative survey of 6109 individuals. In this qualitative study, we first familiarized ourselves with the free-text responses and hand-coded the first 200 responses until we reached saturation. We then created a codebook, initial themes, subthemes, and illustrative quotes. Subsequently, we prompted ChatGPT-4o to analyze the entire dataset of 3931 responses and identify frequent keywords and generate themes and quotable quotes. We validated responses by comparing the AI's keyword counts to qualitative software (NVivo, Lumivero) counts and cross-validating AI-generated quotes with the original transcripts.

Results: We identified several key themes: surrogates more often chose comfort care for care recipients with dementia, particularly at advanced stages. They also strongly weighed the patients' perceived quality of life and functional status. Many reported making surrogate decisions based on their own lived experiences or values, rather than making decisions aligned with the patients' previously stated wishes. There was no significant difference between the AI and qualitative software's keyword counts. The most frequent keywords included "life" (2051/81,713, 2.51%), "quality" (903/81,713, 1.11%), and dementia (507/81,713, 0.62%). Overall, AI-generated themes closely aligned with aforementioned human-generated themes. Manual coding of the first 200 free-text responses required 4 hours, including codebook development. In contrast, ChatGPT-4o generated themes in <10 seconds using the predefined codebook. However, dataset preparation, output verification, iterative prompting, debugging, and validation required several weeks.

Conclusions: Surrogates often base end-of-life decisions on dementia stage, perceived quality of life, and their own lived experiences, rather than patient preferences. Using an AI chatbot to perform qualitative analysis on free-text responses may help extend the work of qualitatively trained investigators, especially for large datasets such as free-text responses to large surveys.

背景:对于代理人如何为缺乏自主决策能力的患者做出临终关怀选择,我们知之甚少。目的:本研究旨在(1)确定参与者对一项关于临终关怀中替代决策的全国性代表性小问卷调查的自由文本回答中出现的关键主题;(2)确定先进的人工智能(AI)聊天机器人是否可以帮助我们准确有效地进行定性分析。方法:我们的数据集包括来自全国6109人的代表性调查的3931份自由文本回复。在这个定性研究中,我们首先熟悉自由文本回复,并对前200个回复进行手工编码,直到达到饱和状态。然后我们创建了一个代码本、初始主题、子主题和说明性引用。随后,我们促使chatgpt - 40分析3931个回复的整个数据集,识别频繁的关键词,并生成主题和可引用的引语。我们通过将人工智能的关键字计数与定性软件(NVivo、Lumivero)计数进行比较,并将人工智能生成的引文与原始文本进行交叉验证,从而验证了回答。结果:我们确定了几个关键主题:代理人更经常为患有痴呆症的护理对象选择舒适的护理,特别是在晚期。他们还强烈衡量了患者的生活质量和功能状态。许多人报告说,他们根据自己的生活经历或价值观做出替代决定,而不是根据患者先前陈述的愿望做出决定。人工智能和定性软件的关键词数量没有显著差异。最常见的关键词包括“生活”(2051/ 81713,2.51%)、“质量”(903/ 81713,1.11%)和痴呆症(507/ 81713,0.62%)。总的来说,人工智能生成的主题与前面提到的人类生成的主题密切相关。前200个自由文本响应的手工编码需要4个小时,包括代码本的开发。相比之下,chatgpt - 40在结论中产生了主题:代理人通常根据痴呆症阶段、感知的生活质量和他们自己的生活经历做出临终决定,而不是患者的偏好。使用人工智能聊天机器人对自由文本回复进行定性分析可能有助于扩展经过定性训练的调查人员的工作,特别是对于大型数据集,如大型调查的自由文本回复。
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引用次数: 0
Ethical and Quality of Care-Related Challenges of Digital Health Twins in Care Settings for Older Adults: Scoping Review. 老年人护理环境中数字健康双胞胎护理相关挑战的伦理和质量:范围审查
IF 4.8 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-10-28 DOI: 10.2196/73925
Md Shafiqur Rahman Jabin, Ayesha Mirza, Adaobi Ilodibe, Tillal Eldabi, Emilia Vann Yaroson
<p><strong>Background: </strong>Digital health twins (DHTs) have been evolving with their diverse applications in medicine, particularly in care settings for older adults, in response to the increasing demands of older adults. Despite its numerous benefits, the optimal implementation of DHTs has faced several challenges, particularly in terms of ethics and quality of care. Given the continuous rise in the need for such care and the evident potential for DHTs to meet these needs, this review seeks to identify and address the gaps in research knowledge to enhance DHT implementation.</p><p><strong>Objective: </strong>The review aims to compile and synthesize the best available evidence regarding the issues associated with quality of care, the ethical implications of DHTs, and the strategies undertaken to overcome those challenges in care settings for older adults.</p><p><strong>Methods: </strong>The review followed the Joanna Briggs Institute (JBI) methodology as a guide. The published studies were searched through CINAHL, MEDLINE, JBI, and Web of Science. The unpublished studies were searched through Mednar, Trove, OCLC WorldCat, and Dissertations and Theses. Studies published in English from 2016 were considered. This review included studies of older individuals (aged 60 years and older) undergoing care delivery associated with DHTs and respective care providers. The concept involved the application of technology, and the context included studies based on care settings for older adults. A broad scope of evidence, including quantitative, qualitative, text, and opinion studies, was considered. In addition, 2 independent reviewers screened the titles and abstracts and reviewed the full text.</p><p><strong>Results: </strong>The results will be presented in a PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) flow diagram. A total of 2 draft charting tables were developed and presented. A summary of the characteristics of the included studies was then described in terms of location, study sites, timing, participants, and outcomes measured or phenomena of interest. A result-based convergent (integrated) synthesis design was used to identify 5 key challenges. Those challenges included (1) data security and privacy concerns, (2) equity and accessibility of health care, (3) effectiveness concerning context, timing, and location, (4) ethical implications regarding autonomy, consent, and overdiagnosis, and (5) the impact of DHTs on health care workflows and provider workload.</p><p><strong>Conclusions: </strong>The studies reviewed reveal several critical characteristics regarding the implementation of DHT technologies and their associated ethical considerations, particularly in terms of safety, equity, timing, location, participant characteristics, and workflow impact. The implications of these challenges emphasize the necessity for more practical ethical guidelines and policy frameworks to mitigate the potential risks associated wi
背景:为了应对老年人日益增长的需求,数字健康双胞胎(dht)在医学,特别是老年人护理环境中的各种应用不断发展。尽管有许多好处,但最佳实施dht面临着一些挑战,特别是在道德和护理质量方面。鉴于对此类护理的需求不断增加,以及DHT满足这些需求的明显潜力,本审查旨在确定和解决研究知识方面的差距,以加强DHT的实施。目的:本综述旨在汇编和综合有关护理质量、dht的伦理影响以及在老年人护理环境中克服这些挑战所采取的策略等问题的最佳证据。方法:采用乔安娜布里格斯研究所(Joanna Briggs Institute, JBI)的研究方法。已发表的研究通过CINAHL、MEDLINE、JBI和Web of Science进行检索。未发表的研究通过Mednar, Trove, OCLC WorldCat和学位论文和论文进行搜索。2016年用英语发表的研究被纳入考虑范围。本综述包括老年人(60岁及以上)接受与dht相关的护理和各自的护理提供者的研究。这个概念涉及到技术的应用,背景包括基于老年人护理环境的研究。广泛的证据,包括定量、定性、文本和意见研究,被考虑。此外,2名独立审稿人对标题和摘要进行了筛选,并对全文进行了审稿。结果:结果将在PRISMA(系统评价和荟萃分析的首选报告项目)流程图中显示。共编制并提出了2份图表草案。然后根据地点、研究地点、时间、参与者和测量结果或感兴趣的现象来描述所纳入研究的特征摘要。采用基于结果的聚合(集成)综合设计来确定5个关键挑战。这些挑战包括(1)数据安全和隐私问题,(2)卫生保健的公平性和可及性,(3)有关背景、时间和地点的有效性,(4)有关自主、同意和过度诊断的伦理影响,以及(5)dht对卫生保健工作流程和提供者工作量的影响。结论:回顾的研究揭示了DHT技术实施的几个关键特征及其相关的伦理考虑,特别是在安全性、公平性、时间、地点、参与者特征和工作流程影响方面。这些挑战的影响强调需要更实用的伦理准则和政策框架,以减轻与老年护理中DHT应用相关的潜在风险。应该进行进一步的研究,以检查护理质量的其他方面,如可及性、及时性、可接受性和适当性。
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引用次数: 0
The Experience and Impact of Digital Technologies on Indigenous Populations in New Zealand During the COVID-19 Pandemic and Cyclone Gabrielle: The Kaupapa Māori Methodology. 在2019冠状病毒病大流行和加布里埃尔飓风期间,数字技术对新西兰土著居民的经验和影响:考帕帕Māori方法。
IF 4.8 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-10-28 DOI: 10.2196/73974
Dianne Wepa, Shiji Thomas, Md Shafiqur Rahman Jabin

Background: Pandemics, such as COVID-19, and climate change-related catastrophic weather events are increasing, impacting social connectedness within communities by disrupting social cohesion, increasing loneliness, and affecting mental health and social well-being. Digital technology, in addition to being used for communication, education, and business transactions, also plays a vital role in maintaining a country's health and well-being, as well as sustaining economic growth.

Objective: This study aimed to explore the experiences of Māori kaumātua in using digital technology to meet their health needs within Ngāti Kahungunu, North Island, New Zealand, during the COVID-19 pandemic and Cyclone Gabrielle.

Methods: This qualitative study employed the Kaupapa Māori methodology to understand the challenges, resilience, and approaches used by Māori to maintain connectedness and access essential services. An inductive approach to thematic analysis, as recommended by Braun and Clarke, was used to ensure a thorough and robust data analysis. The user characteristic was assessed on a semantic level using the information provided in the narrative text.

Results: The findings highlight the role of digital technology in disaster management and underscore the urgent need to address digital disparities in support of vulnerable populations. In this study, 14 individuals were interviewed, comprising 71% (n=10) women and 29% (n=4) men. These participants fell into different age groups, with 9 participants being 65 years or older (older adults). Of the total participants, 43% (n=6) were limited users, 43% (n=6) comprised confident users, and the rest (n=2; 14%) were normal users. A total of 6 themes emerged from the interview data: social connectedness and resilience, digital literacy and access to information, barriers to telecommunications and digital technology, cultural appropriateness and psychological barriers, perceived threats of feeling insecure, and impact on mental health and emotional well-being.

Conclusions: Vulnerable situations such as pandemics and extreme weather events can have tremendous effects on the lives of Indigenous people who live remotely. The study also focused on the actions that should be taken to mitigate these challenges and overcome difficult circumstances, such as the pandemic and the cyclone. The recommendations include a better health care system and improved coordination among care providers, user-friendly digital solutions, ensuring local funding and community services, establishing training processes for basic digital skills, and fostering leadership and partnerships with Indigenous New Zealanders.

背景:COVID-19等大流行病和与气候变化有关的灾难性天气事件正在增加,通过破坏社会凝聚力、增加孤独感以及影响心理健康和社会福祉,影响社区内的社会连通性。数字技术除了用于通信、教育和商业交易之外,在维持一个国家的健康和福祉以及维持经济增长方面也发挥着至关重要的作用。目的:本研究旨在探讨在2019冠状病毒病(COVID-19)大流行和强热带气旋加布里埃尔(Gabrielle)期间,新西兰北岛Ngāti卡洪古努(Kahungunu)利用数字技术满足其健康需求的经验。方法:本定性研究采用Kaupapa Māori方法来了解Māori在保持连通性和获取基本服务方面所面临的挑战、弹性和方法。采用Braun和Clarke推荐的归纳方法进行主题分析,以确保数据分析的全面和稳健。使用叙事文本中提供的信息在语义层面上评估用户特征。结果:研究结果强调了数字技术在灾害管理中的作用,并强调了在支持弱势群体方面解决数字差距的迫切需要。在这项研究中,采访了14个人,其中71% (n=10)为女性,29% (n=4)为男性。这些参与者分为不同的年龄组,有9名参与者年龄在65岁或以上(老年人)。在所有参与者中,43% (n=6)是有限用户,43% (n=6)是自信用户,其余(n=2; 14%)是正常用户。访谈数据共产生了6个主题:社会联系和弹性、数字素养和信息获取、电信和数字技术的障碍、文化适当性和心理障碍、感觉不安全的威胁以及对心理健康和情感福祉的影响。结论:流行病和极端天气事件等脆弱情况可能对偏远地区土著人民的生活产生巨大影响。该研究还侧重于为减轻这些挑战和克服诸如大流行病和旋风等困难情况应采取的行动。这些建议包括更好的医疗保健系统和改善医疗服务提供者之间的协调,用户友好的数字解决方案,确保地方资金和社区服务,建立基本数字技能的培训流程,以及促进与新西兰土著人民的领导和伙伴关系。
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引用次数: 0
Urban Quality and Biochemical, Hematological, and Nutritional Markers in Older Adults: Cross-Sectional Geospatial Study. 城市质量与老年人生化、血液学和营养指标:横断面地理空间研究。
IF 4.8 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-10-27 DOI: 10.2196/74313
Carlos Mena, Yony Ormazabal, Nacim Molina, Eduardo Fuentes, Juan Carlos Cantillana, Victoria Villalobos, Moises Sandoval, Ivan Palomo, Diego Arauna
<p><strong>Background: </strong>The urban environment is an important determinant of frailty, primarily through factors such as infrastructure that supports physical activity, availability of social and medical support, and access to nutritious food. Given the increasing aging population, understanding the link between urban quality, frailty, and metabolic health is crucial for effective public health and urban planning interventions.</p><p><strong>Objective: </strong>This study aims to quantify the impact of distinct urban domains (built-environment characteristics, accessibility to essential services, availability of green and recreational spaces, and neighborhood socioeconomic context) on frailty status, nutritional profile, and hematological or biochemical biomarkers in community-dwelling older adults by integrating geospatial analysis.</p><p><strong>Methods: </strong>A cohort of 251 older adults (aged older than 65 years) was studied. Frailty was assessed using the Frailty Trait Scale 5, and nutritional status was determined using the Controlling Nutritional Status score. Hematological and biochemical parameters were evaluated in a subset of 70 participants by MINDRAY automatic equipment. A spatial analysis of frailty was conducted by incorporating Geographic Information System layers that mapped the distribution of urban facilities, including fruit and vegetable shops, senior centers, pharmacies, emergency health centers, parks and squares, community centers, and exercise facilities. Statistical analyses included t tests, Mann-Whitney U test, ANOVA, and correlation analyses.</p><p><strong>Results: </strong>The prevalence of frailty was 17.5%. Frail individuals exhibited significantly higher BMI (mean 31.5, SD  4.4 vs mean 28.5,  SD 4.5 kg/m²; P=.0001). When comparing the upper (Q4) and lower (Q1) quartiles of urban quality, Q4 participants had higher Frailty Trait Scale 5 scores (mean 15.2,  SD 7.4 vs mean 11.8, SD  6.4; P=.0334) and lower handgrip strength (mean 19.1, SD 4.4 vs mean 22.8, SD 7.3 kg; P=.006). Frail individuals resided significantly closer to emergency health centers (P=.0010), family health centers (P=.0412), and exercise facilities (P=.0322). In addition, bilirubin (Spearman ρ=0.33; P=.0049), serum iron (Spearman ρ=0.27; P=.0272), transferrin saturation (Spearman ρ=0.24; P=.0386), red blood cell count (Spearman ρ=0.26; P=.0303), and red blood cell distribution width (Spearman ρ=0.23; P=.0462) were positively correlated with urban quality. Frail participants also had higher Controlling Nutritional Status scores (P=.0323), which were positively correlated with urban quality (Spearman ρ=0.25; P=.0359).</p><p><strong>Conclusions: </strong>Urban quality was significantly associated with hematological parameters, nutritional status, and frailty. Frail individuals in areas with better urban quality exhibit lower handgrip strength, higher frailty scores, and greater proximity to emergency rooms, community health centers, and exerc
背景:城市环境是脆弱的一个重要决定因素,主要是通过支持身体活动的基础设施、社会和医疗支持的可获得性以及获得营养食品等因素。鉴于人口老龄化日益加剧,了解城市质量、脆弱性和代谢健康之间的联系对于有效的公共卫生和城市规划干预至关重要。目的:本研究旨在通过整合地理空间分析,量化不同城市域(建筑环境特征、基本服务可及性、绿色和娱乐空间的可用性以及社区社会经济背景)对社区居住老年人的虚弱状态、营养状况和血液或生化生物标志物的影响。方法:对251名年龄在65岁以上的老年人进行队列研究。使用脆弱性状量表5评估虚弱程度,使用控制营养状况评分确定营养状况。使用MINDRAY自动设备对70名参与者的血液学和生化参数进行评估。利用地理信息系统层对城市设施的分布进行了空间分析,包括水果和蔬菜商店、老年中心、药房、急救中心、公园和广场、社区中心和锻炼设施。统计分析包括t检验、Mann-Whitney U检验、方差分析和相关分析。结果:虚弱的患病率为17.5%。体弱个体表现出更高的BMI(平均31.5, SD 4.4 vs平均28.5,  SD 4.5 kg/m²;P= 0.0001)。当比较城市质量的上(Q4)和下(Q1)四分位数时,Q4参与者的脆弱特征量表5得分较高(平均15.2,  SD 7.4 vs平均11.8,SD 6.4;P= 0.034),握力较低(平均19.1,SD 4.4 vs平均22.8,SD 7.3 kg; P= 0.006)。体弱个体居住在离急救中心(P= 0.0010)、家庭健康中心(P= 0.0412)和运动设施(P= 0.0322)较近的地方。此外,胆红素(Spearman ρ=0.33; P= 0.0049)、血清铁(Spearman ρ=0.27; P= 0.0272)、转铁蛋白饱和度(Spearman ρ=0.24; P= 0.086)、红细胞计数(Spearman ρ=0.26; P= 0.0303)和红细胞分布宽度(Spearman ρ=0.23; P= 0.0462)与城市质量呈正相关。体弱的参与者也有较高的控制营养状态评分(P= 0.0323),这与城市质量呈正相关(Spearman ρ=0.25; P= 0.0359)。结论:城市质量与血液学参数、营养状况和虚弱程度显著相关。在城市质量较好的地区,体弱多病的个体表现出较低的握力,较高的虚弱评分,并且更接近急诊室、社区卫生中心和锻炼设施。这种空间分布可能反映了体弱参与者获得医疗保健和娱乐资源的可达性较高。城市规划和公共卫生战略应侧重于创造有利于老年人的环境,以预防虚弱和改善健康结果。
{"title":"Urban Quality and Biochemical, Hematological, and Nutritional Markers in Older Adults: Cross-Sectional Geospatial Study.","authors":"Carlos Mena, Yony Ormazabal, Nacim Molina, Eduardo Fuentes, Juan Carlos Cantillana, Victoria Villalobos, Moises Sandoval, Ivan Palomo, Diego Arauna","doi":"10.2196/74313","DOIUrl":"10.2196/74313","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;The urban environment is an important determinant of frailty, primarily through factors such as infrastructure that supports physical activity, availability of social and medical support, and access to nutritious food. Given the increasing aging population, understanding the link between urban quality, frailty, and metabolic health is crucial for effective public health and urban planning interventions.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;This study aims to quantify the impact of distinct urban domains (built-environment characteristics, accessibility to essential services, availability of green and recreational spaces, and neighborhood socioeconomic context) on frailty status, nutritional profile, and hematological or biochemical biomarkers in community-dwelling older adults by integrating geospatial analysis.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A cohort of 251 older adults (aged older than 65 years) was studied. Frailty was assessed using the Frailty Trait Scale 5, and nutritional status was determined using the Controlling Nutritional Status score. Hematological and biochemical parameters were evaluated in a subset of 70 participants by MINDRAY automatic equipment. A spatial analysis of frailty was conducted by incorporating Geographic Information System layers that mapped the distribution of urban facilities, including fruit and vegetable shops, senior centers, pharmacies, emergency health centers, parks and squares, community centers, and exercise facilities. Statistical analyses included t tests, Mann-Whitney U test, ANOVA, and correlation analyses.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The prevalence of frailty was 17.5%. Frail individuals exhibited significantly higher BMI (mean 31.5, SD  4.4 vs mean 28.5,  SD 4.5 kg/m²; P=.0001). When comparing the upper (Q4) and lower (Q1) quartiles of urban quality, Q4 participants had higher Frailty Trait Scale 5 scores (mean 15.2,  SD 7.4 vs mean 11.8, SD  6.4; P=.0334) and lower handgrip strength (mean 19.1, SD 4.4 vs mean 22.8, SD 7.3 kg; P=.006). Frail individuals resided significantly closer to emergency health centers (P=.0010), family health centers (P=.0412), and exercise facilities (P=.0322). In addition, bilirubin (Spearman ρ=0.33; P=.0049), serum iron (Spearman ρ=0.27; P=.0272), transferrin saturation (Spearman ρ=0.24; P=.0386), red blood cell count (Spearman ρ=0.26; P=.0303), and red blood cell distribution width (Spearman ρ=0.23; P=.0462) were positively correlated with urban quality. Frail participants also had higher Controlling Nutritional Status scores (P=.0323), which were positively correlated with urban quality (Spearman ρ=0.25; P=.0359).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;Urban quality was significantly associated with hematological parameters, nutritional status, and frailty. Frail individuals in areas with better urban quality exhibit lower handgrip strength, higher frailty scores, and greater proximity to emergency rooms, community health centers, and exerc","PeriodicalId":36245,"journal":{"name":"JMIR Aging","volume":"8 ","pages":"e74313"},"PeriodicalIF":4.8,"publicationDate":"2025-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12558422/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145379215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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JMIR Aging
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