Pub Date : 2019-10-31DOI: 10.29328/journal.cjog.1001031
M. Barretina-Ginesta, J. Galceran, H. Pla, C. Meléndez, A. C. Bagué, A. Ameijide, M. Carulla, J. Barretina, A. Izquierdo, R. Marcos-Gragera
Background: Breast cancer (BC) is one of the most prevalent malignancies. BC survivors have higher risk of second primary cancers than the general population. There is an increased interest in BC survivor management, including the prevention of these second cancers. The aim of this study was to assess the risk of gynaecological malignancy (GM) as second neoplasm among BC patients in our population. Methods: Patients with invasive BC diagnosed from 1980 to 2014 included in the Girona Cancer Registry were included. The incidence of second GM in these patients was compared to those in the general population. Second primary cancer was stated as a tumour diagnosed after 2 months from the BC diagnosis. Standardized incidence ratios (SIR) and absolute excess of risk (AER) were calculated. Results: 9,717 patients were diagnosed with invasive BC during this period, with a median age at diagnosis of 61 years, and a median follow-up of 7.9 years. 117 of them developed a second GM. By tumour type, the only statistically signifi cant higher SIR was observed for corpus uteri cancer (SIR:2.28 95% CI 1.82-2.83; AER:6.43 95% CI 4.13-9.14). After reviewing the histology of the corpus uteri cancer cases, we found that 71.4% were type I (endometrioid adenocarcinoma), 15.5% type II (serous adenocarcinomas and clear cell carcinomas), 10.7% carcinosarcomas, 2.4% sarcomas and there were no unspecifi ed malignant neoplasms. Conclusion: BC survivors have an increased risk of corpus uteri cancer, with an increase in unfavourable histologies compared to the general population. Lifelong primary and secondary prevention interventions should be recommended for these patients.
背景:乳腺癌(BC)是最常见的恶性肿瘤之一。BC幸存者患第二原发癌症的风险高于一般人群。人们对BC幸存者管理的兴趣越来越大，包括预防这些第二种癌症。本研究的目的是评估妇科恶性肿瘤(GM)作为我们人群中BC患者的第二大肿瘤的风险。方法:纳入赫罗纳癌症登记处1980 - 2014年诊断为浸润性BC的患者。将这些患者的第二次GM发生率与普通人群进行比较。第二原发癌是在BC诊断后2个月诊断出的肿瘤。计算标准化发病率比(SIR)和绝对超额风险(AER)。结果:9717例患者在此期间被诊断为浸润性BC，诊断时的中位年龄为61岁，中位随访时间为7.9年。其中117例发生了第二次GM。按肿瘤类型划分，唯一有统计学意义的高SIR是子宫癌(SIR:2.28 95% CI 1.82-2.83;比值:6.43 (95% ci 4.13-9.14)。在回顾子宫癌病例的组织学后，我们发现71.4%为I型(子宫内膜样腺癌)，15.5%为II型(浆液性腺癌和透明细胞癌)，10.7%为癌肉瘤，2.4%为肉瘤，没有未明确的恶性肿瘤。结论:与一般人群相比，BC幸存者患子宫肌癌的风险增加，不利组织学增加。应建议对这些患者进行终身一级和二级预防干预。
{"title":"Gynaecological malignancies after breast cancer diagnosis: A population-based study","authors":"M. Barretina-Ginesta, J. Galceran, H. Pla, C. Meléndez, A. C. Bagué, A. Ameijide, M. Carulla, J. Barretina, A. Izquierdo, R. Marcos-Gragera","doi":"10.29328/journal.cjog.1001031","DOIUrl":"https://doi.org/10.29328/journal.cjog.1001031","url":null,"abstract":"Background: Breast cancer (BC) is one of the most prevalent malignancies. BC survivors have higher risk of second primary cancers than the general population. There is an increased interest in BC survivor management, including the prevention of these second cancers. The aim of this study was to assess the risk of gynaecological malignancy (GM) as second neoplasm among BC patients in our population. Methods: Patients with invasive BC diagnosed from 1980 to 2014 included in the Girona Cancer Registry were included. The incidence of second GM in these patients was compared to those in the general population. Second primary cancer was stated as a tumour diagnosed after 2 months from the BC diagnosis. Standardized incidence ratios (SIR) and absolute excess of risk (AER) were calculated. Results: 9,717 patients were diagnosed with invasive BC during this period, with a median age at diagnosis of 61 years, and a median follow-up of 7.9 years. 117 of them developed a second GM. By tumour type, the only statistically signifi cant higher SIR was observed for corpus uteri cancer (SIR:2.28 95% CI 1.82-2.83; AER:6.43 95% CI 4.13-9.14). After reviewing the histology of the corpus uteri cancer cases, we found that 71.4% were type I (endometrioid adenocarcinoma), 15.5% type II (serous adenocarcinomas and clear cell carcinomas), 10.7% carcinosarcomas, 2.4% sarcomas and there were no unspecifi ed malignant neoplasms. Conclusion: BC survivors have an increased risk of corpus uteri cancer, with an increase in unfavourable histologies compared to the general population. Lifelong primary and secondary prevention interventions should be recommended for these patients.","PeriodicalId":36268,"journal":{"name":"Journal of Clinical Obstetrics and Gynecology","volume":"145 41","pages":""},"PeriodicalIF":0.1,"publicationDate":"2019-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72539440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-18DOI: 10.29328/journal.cjog.1001030
C. Yazbeck, A. Boukadida, C. Chauvin, A. Margulies, S. Falcone
1Department of Obstetrics, Gynecology and Reproductive Medicine, CMC Hartmann Cherest Clinics, 26 Bd Victor Hugo 92200 Neuilly Sur Seine, France 2Department of Obstetrics, Gynecology and Reproductive Medicine, Foch University Hospital, 40 rue Worth, 92150 Suresnes, France 3Department of Obstetrics, Gynecology and Reproductive Medicine, Bichat Claude Bernard University Hospital, APHP, 75018 Paris, France More Information
1 CMC Hartmann Cherest诊所妇产科和生殖医学科，26 Bd Victor Hugo 92200法国塞纳河畔纽伊2福奇大学医院妇产科和生殖医学科，40 rue Worth, 92150 Suresnes，法国3 Bichat Claude Bernard大学医院妇产科和生殖医学科，APHP, 75018法国巴黎
{"title":"Effect of laparoscopic salpingectomy on subsequent ovarian response after controlled ovarian hyperstimulation","authors":"C. Yazbeck, A. Boukadida, C. Chauvin, A. Margulies, S. Falcone","doi":"10.29328/journal.cjog.1001030","DOIUrl":"https://doi.org/10.29328/journal.cjog.1001030","url":null,"abstract":"1Department of Obstetrics, Gynecology and Reproductive Medicine, CMC Hartmann Cherest Clinics, 26 Bd Victor Hugo 92200 Neuilly Sur Seine, France 2Department of Obstetrics, Gynecology and Reproductive Medicine, Foch University Hospital, 40 rue Worth, 92150 Suresnes, France 3Department of Obstetrics, Gynecology and Reproductive Medicine, Bichat Claude Bernard University Hospital, APHP, 75018 Paris, France More Information","PeriodicalId":36268,"journal":{"name":"Journal of Clinical Obstetrics and Gynecology","volume":"6 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2019-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75609511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-18DOI: 10.29328/journal.cjog.1001029
P. Korovessis, Rania Antonaki, Spyridon Zacharatos, V. Syrimpeis
Study design: A consecutive case series study. Purpose: To investigate whether Low Back Pain (LBP) in women with primary singleton pregnancy induces disability. Background: LBP is reported to be increased in pregnants than in non-pregnant women. Different outcome measures have been used to search for correlations between pain and disability. Method: 167 pregnant women aged 30 ± 3.5 years participated. Two equal categorial age groups were constructed: Group A included women aged 23-29 years, and Group B women aged 30-39 years. Their weight was 76 ± 13 kg prepartum and the Body Mass index (BMI was 28 ± 4 prepartum. Visual Analogue Scale (VAS) was used for LBP pain intensity and Oswestry Disability Scale (ODI) for disability estimation in the last three months prepartum and in the first three months postpartum. Results: The women weight was 67 ± 13 kg postpartum. The BMI was 24 ± 4 postpartum. There was no difference in VAS and ODI scores versus BMI, weight and height between the two age groups in both periods of observation: prepartum and postpartum. Prepartum, 81.4% of women claimed LBP that dropped to 55.5% postpartum. ODI score dropped from 19.5 ± 13.6% prepartum to 11 ± 12% postpartum. The ODI subscales that showed significant reduction postpartum were: Pain intensity (P=0.002); working (P=0.009); sitting (P=0.004); standing (P=0.003); sleeping (P=0.008); and traveling (P=0.006). VAS prepartum was increasing as the weight was increasing in both periods of observation (P=0.015 and P=0.051) respectively. VAS prepartum was significantly correlated with BMI prepartum (P=0.019) and postpartum (P=0.028). Discussion: Physical disability in pregnant women was low and reduced following delivery. Disability was linked with LBP intensity, weight, BMI and height, but not with age or educational level.
{"title":"Low back pain induces disability of women in primary uncomplicated pregnancy","authors":"P. Korovessis, Rania Antonaki, Spyridon Zacharatos, V. Syrimpeis","doi":"10.29328/journal.cjog.1001029","DOIUrl":"https://doi.org/10.29328/journal.cjog.1001029","url":null,"abstract":"Study design: A consecutive case series study. Purpose: To investigate whether Low Back Pain (LBP) in women with primary singleton pregnancy induces disability. Background: LBP is reported to be increased in pregnants than in non-pregnant women. Different outcome measures have been used to search for correlations between pain and disability. Method: 167 pregnant women aged 30 ± 3.5 years participated. Two equal categorial age groups were constructed: Group A included women aged 23-29 years, and Group B women aged 30-39 years. Their weight was 76 ± 13 kg prepartum and the Body Mass index (BMI was 28 ± 4 prepartum. Visual Analogue Scale (VAS) was used for LBP pain intensity and Oswestry Disability Scale (ODI) for disability estimation in the last three months prepartum and in the first three months postpartum. Results: The women weight was 67 ± 13 kg postpartum. The BMI was 24 ± 4 postpartum. There was no difference in VAS and ODI scores versus BMI, weight and height between the two age groups in both periods of observation: prepartum and postpartum. Prepartum, 81.4% of women claimed LBP that dropped to 55.5% postpartum. ODI score dropped from 19.5 ± 13.6% prepartum to 11 ± 12% postpartum. The ODI subscales that showed significant reduction postpartum were: Pain intensity (P=0.002); working (P=0.009); sitting (P=0.004); standing (P=0.003); sleeping (P=0.008); and traveling (P=0.006). VAS prepartum was increasing as the weight was increasing in both periods of observation (P=0.015 and P=0.051) respectively. VAS prepartum was significantly correlated with BMI prepartum (P=0.019) and postpartum (P=0.028). Discussion: Physical disability in pregnant women was low and reduced following delivery. Disability was linked with LBP intensity, weight, BMI and height, but not with age or educational level.","PeriodicalId":36268,"journal":{"name":"Journal of Clinical Obstetrics and Gynecology","volume":"8 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2019-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84164470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-11DOI: 10.29328/journal.cjog.1001028
M. Abolfotouh, H. Al-Anazi, Samar N. Hassan
{"title":"The validity of progesterone level on hCG injection day in the prediction of IVF/ICSI cycles’ outcome","authors":"M. Abolfotouh, H. Al-Anazi, Samar N. Hassan","doi":"10.29328/journal.cjog.1001028","DOIUrl":"https://doi.org/10.29328/journal.cjog.1001028","url":null,"abstract":"","PeriodicalId":36268,"journal":{"name":"Journal of Clinical Obstetrics and Gynecology","volume":"85 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2019-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85616366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-07-12DOI: 10.29328/JOURNAL.CJOG.1001027
A. B. Fazari, Maria Eugenia Ramirez Aristondo, F. Azim, Basma Almaamari, Rasha Eltayeb
Myometrial tissue trauma and scarring are the main predisposing factors resulting in both placenta previa and morbidly adherent placenta. This can be caused by multiple Caesarean sections; this risk rises as the number of prior Caesarean sections increases. Placenta accreta spectrum is not exclusively a consequence of Caesarean delivery. Other surgical trauma to the integrity of the uterine endometrium and/or super icial myometrium, such as dilatation and curettage and other surgical injuries to the myometrium: manual removal of the placenta, postpartum endometritis or myomectomy, has been associated with accreta placentation in subsequent pregnancies, as well as, assisted reproductive technology and maternal smoking.
{"title":"Methotrexate in management of Morbidly Adherent Placenta at Latifa Hospital, DHA, Dubai, UAE.: Case report","authors":"A. B. Fazari, Maria Eugenia Ramirez Aristondo, F. Azim, Basma Almaamari, Rasha Eltayeb","doi":"10.29328/JOURNAL.CJOG.1001027","DOIUrl":"https://doi.org/10.29328/JOURNAL.CJOG.1001027","url":null,"abstract":"Myometrial tissue trauma and scarring are the main predisposing factors resulting in both placenta previa and morbidly adherent placenta. This can be caused by multiple Caesarean sections; this risk rises as the number of prior Caesarean sections increases. Placenta accreta spectrum is not exclusively a consequence of Caesarean delivery. Other surgical trauma to the integrity of the uterine endometrium and/or super icial myometrium, such as dilatation and curettage and other surgical injuries to the myometrium: manual removal of the placenta, postpartum endometritis or myomectomy, has been associated with accreta placentation in subsequent pregnancies, as well as, assisted reproductive technology and maternal smoking.","PeriodicalId":36268,"journal":{"name":"Journal of Clinical Obstetrics and Gynecology","volume":"31 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2019-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87758220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-07-02DOI: 10.29328/JOURNAL.CJOG.1001023
J. Akowuah, B. Owusu
{"title":"Focused Antenatal Care in urban Ghana: A qualitative study into physical accessibility of maternal health services in Kwabre East Municipality","authors":"J. Akowuah, B. Owusu","doi":"10.29328/JOURNAL.CJOG.1001023","DOIUrl":"https://doi.org/10.29328/JOURNAL.CJOG.1001023","url":null,"abstract":"","PeriodicalId":36268,"journal":{"name":"Journal of Clinical Obstetrics and Gynecology","volume":"2 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2019-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82030620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-07-02DOI: 10.29328/JOURNAL.CJOG.1001025
Tumilara Busayo Amoo, O. S. Ajayi
{"title":"Maternal mortality and factors affecting it, among pregnant women in Abeokuta South, Nigeria","authors":"Tumilara Busayo Amoo, O. S. Ajayi","doi":"10.29328/JOURNAL.CJOG.1001025","DOIUrl":"https://doi.org/10.29328/JOURNAL.CJOG.1001025","url":null,"abstract":"","PeriodicalId":36268,"journal":{"name":"Journal of Clinical Obstetrics and Gynecology","volume":"53 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2019-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76492604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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