首页 > 最新文献

Journal of Clinical Obstetrics and Gynecology最新文献

英文 中文
Comparison of Serum D-dimer, Fibrinogen and Platelet Levels in Pregnant Women with COVID-19 Symptoms According to PCR Positivity or PCR Negativity: A Case-Control Study PCR阳性和PCR阴性孕妇血清d -二聚体、纤维蛋白原和血小板水平的比较:一项病例对照研究
IF 0.1 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2021-01-01 DOI: 10.5336/jcog.2021-85851
Gizem Cura Şahin, Buğra Şahin
Objective: The diagnosis and treatment of coronavirus disease-2019 (COVID-19) infection may be delayed in pregnant women because of the non-specific symptoms and limited application of the necessary radiological tests. The aim of this study was to compare the serum D-dimer, fibrinogen, and platelet levels in pregnant patients with COVID-19 symptoms and polymerase chain reaction (PCR) positivity or PCR negativity. Material and Methods: The study included 100 pregnant women who presented at the Gynaecology and Obstetrics Clinic of Tokat State Hospital between April 2020 and December 2020 with symptoms of COVID-19 infection (fever, cough, shortness of breath). Half of the patients were COVID-19 PCR positive and half were negative. The groups were compared in respect of age, gravida, gestational week, COVID-19 symptoms (fever, cough, shortness of breath), serum D-dimer, fibrinogen, and platelet values.
目的:新型冠状病毒病-2019 (COVID-19)感染的孕妇由于症状不特异性和必要的影像学检查应用有限,可能会延误诊断和治疗。本研究的目的是比较具有COVID-19症状和聚合酶链反应(PCR)阳性或阴性的妊娠患者血清d -二聚体、纤维蛋白原和血小板水平。材料和方法:该研究包括2020年4月至2020年12月期间在托卡特州立医院妇产科诊所就诊的100名孕妇,她们出现了COVID-19感染症状(发烧、咳嗽、呼吸短促)。新冠肺炎PCR阳性患者占一半,阴性患者占一半。比较两组年龄、妊娠、妊娠周、COVID-19症状(发热、咳嗽、呼吸短促)、血清d -二聚体、纤维蛋白原和血小板值。
{"title":"Comparison of Serum D-dimer, Fibrinogen and Platelet Levels in Pregnant Women with COVID-19 Symptoms According to PCR Positivity or PCR Negativity: A Case-Control Study","authors":"Gizem Cura Şahin, Buğra Şahin","doi":"10.5336/jcog.2021-85851","DOIUrl":"https://doi.org/10.5336/jcog.2021-85851","url":null,"abstract":"Objective: The diagnosis and treatment of coronavirus disease-2019 (COVID-19) infection may be delayed in pregnant women because of the non-specific symptoms and limited application of the necessary radiological tests. The aim of this study was to compare the serum D-dimer, fibrinogen, and platelet levels in pregnant patients with COVID-19 symptoms and polymerase chain reaction (PCR) positivity or PCR negativity. Material and Methods: The study included 100 pregnant women who presented at the Gynaecology and Obstetrics Clinic of Tokat State Hospital between April 2020 and December 2020 with symptoms of COVID-19 infection (fever, cough, shortness of breath). Half of the patients were COVID-19 PCR positive and half were negative. The groups were compared in respect of age, gravida, gestational week, COVID-19 symptoms (fever, cough, shortness of breath), serum D-dimer, fibrinogen, and platelet values.","PeriodicalId":36268,"journal":{"name":"Journal of Clinical Obstetrics and Gynecology","volume":"1 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70762329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Retrospective Analysis of Clinical Features, Maternal and Neonatal Outcomes of COVID-19 patients in an Obstetric Clinic in Ankara, Turkey 土耳其安卡拉一家产科诊所COVID-19患者的临床特征、孕产妇和新生儿结局回顾性分析
IF 0.1 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2021-01-01 DOI: 10.5336/jcog.2021-82263
İlknur Selvi̇, F. Cevher, A. Biri
Objective: To evaluate the effects of coronavirus disease-2019 (COVID-19) infection on clinical and laboratory features;maternal and fetal outcomes. Material and Methods: In this retrospective study, the patients diagnosed with COVID-19 by positive severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) reverse transcription polymerase chain reaction (RT-PCR) and delivered at Koru Hospital (Ankara, Turkey) between March 2020 and February 2021 were included. We obtained demographic, clinical, laboratory features, obstetric and delivery history, maternal and perinatal outcomes from medical records.
目的:探讨新型冠状病毒病(COVID-19)感染对临床和实验室特征、母胎结局的影响。材料与方法:在这项回顾性研究中,纳入了2020年3月至2021年2月在土耳其安卡拉Koru医院(Koru Hospital)经严重急性呼吸综合征-冠状病毒-2 (SARS-CoV-2)逆转录聚合酶链反应(RT-PCR)阳性诊断为COVID-19的患者。我们从医疗记录中获得了人口统计学、临床、实验室特征、产科和分娩史、孕产妇和围产期结局。
{"title":"A Retrospective Analysis of Clinical Features, Maternal and Neonatal Outcomes of COVID-19 patients in an Obstetric Clinic in Ankara, Turkey","authors":"İlknur Selvi̇, F. Cevher, A. Biri","doi":"10.5336/jcog.2021-82263","DOIUrl":"https://doi.org/10.5336/jcog.2021-82263","url":null,"abstract":"Objective: To evaluate the effects of coronavirus disease-2019 (COVID-19) infection on clinical and laboratory features;maternal and fetal outcomes. Material and Methods: In this retrospective study, the patients diagnosed with COVID-19 by positive severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) reverse transcription polymerase chain reaction (RT-PCR) and delivered at Koru Hospital (Ankara, Turkey) between March 2020 and February 2021 were included. We obtained demographic, clinical, laboratory features, obstetric and delivery history, maternal and perinatal outcomes from medical records.","PeriodicalId":36268,"journal":{"name":"Journal of Clinical Obstetrics and Gynecology","volume":"1 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70761720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Urethrocutaneous Fistula After Transobturator Tape Operation 经闭带手术后尿道瘘
IF 0.1 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2021-01-01 DOI: 10.5336/jcog.2021-81586
Alev Esercan, Tuncer Bah eci
Transobturator tapes have demonstrated good outcomes for stress urinary incontinence treatment in women however a delayed urinary tract fistulation can develop after bladder or urethral injury. The purpose of this report was to draw attention to this rare occurrence. CASE: 49 year old woman had undergone transobturator tension free vaginal tape (TOT) operation ten days ago,presented to the emergency room complaining of left groin pain, walking disability and urinary complaint.Blood tests, MRI and CT demonstrated a liquid collection extending from the labia majora to the thigh muscles on the left-hand side that suggested the presence of an abscess.Mesh was removed from the incision line of TOT with urologist.In conclusion, thigh abscesses can occur secondary to unusual pelvic processes. Both urologists and surgeons should have a high index of suspicion when 48 diagnosing such unusual presentations.
经通气带治疗女性压力性尿失禁效果良好,但膀胱或尿道损伤后可出现延迟性尿路瘘。本报告的目的是提请注意这一罕见事件。病例:49岁女性,10天前行经闭口无张力阴道带(TOT)手术,就诊于急诊室,主诉左腹股沟疼痛、行走障碍和泌尿系统不适。血液检查、MRI和CT显示液体从大阴唇延伸到左侧大腿肌肉,提示存在脓肿。与泌尿科医生一起从TOT切口线上取下补片。总之,大腿脓肿可继发于不寻常的骨盆突变。泌尿科医生和外科医生在诊断这种不寻常的表现时都应该高度怀疑。
{"title":"Urethrocutaneous Fistula After Transobturator Tape Operation","authors":"Alev Esercan, Tuncer Bah eci","doi":"10.5336/jcog.2021-81586","DOIUrl":"https://doi.org/10.5336/jcog.2021-81586","url":null,"abstract":"Transobturator tapes have demonstrated good outcomes for stress urinary incontinence treatment in women however a delayed urinary tract fistulation can develop after bladder or urethral injury. The purpose of this report was to draw attention to this rare occurrence. CASE: 49 year old woman had undergone transobturator tension free vaginal tape (TOT) operation ten days ago,presented to the emergency room complaining of left groin pain, walking disability and urinary complaint.Blood tests, MRI and CT demonstrated a liquid collection extending from the labia majora to the thigh muscles on the left-hand side that suggested the presence of an abscess.Mesh was removed from the incision line of TOT with urologist.In conclusion, thigh abscesses can occur secondary to unusual pelvic processes. Both urologists and surgeons should have a high index of suspicion when 48 diagnosing such unusual presentations.","PeriodicalId":36268,"journal":{"name":"Journal of Clinical Obstetrics and Gynecology","volume":"1 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70761759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Challenges of Frozen Section in Borderline Ovarian Tumors: A 10-Year Retrospective Analysis from a Tertiary Gynecological Cancer Center: Retrospective Analysis 冷冻切片在交界性卵巢肿瘤中的挑战:来自三级妇科癌症中心的10年回顾性分析
IF 0.1 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2021-01-01 DOI: 10.5336/jcog.2020-76344
Munip Akalin, Emine Eda Akalın, B. Giray, Canan Kabaca Kocakuşak
{"title":"Challenges of Frozen Section in Borderline Ovarian Tumors: A 10-Year Retrospective Analysis from a Tertiary Gynecological Cancer Center: Retrospective Analysis","authors":"Munip Akalin, Emine Eda Akalın, B. Giray, Canan Kabaca Kocakuşak","doi":"10.5336/jcog.2020-76344","DOIUrl":"https://doi.org/10.5336/jcog.2020-76344","url":null,"abstract":"","PeriodicalId":36268,"journal":{"name":"Journal of Clinical Obstetrics and Gynecology","volume":"1 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70761264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Menstrual Cycle Characteristics of Healthcare Professionals Working at COVID-19 Pandemic Clinics COVID-19大流行诊所医护人员的月经周期特征
IF 0.1 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2021-01-01 DOI: 10.5336/jcog.2021-82054
Sevcan Arzu Arınkan, F. Vural
Objective: The impact of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection on the reproductive system is still not known. We aimed to investigate the menstrual characteristics of healthcare professionals employed in the coronavirus disease2019 (COVID-19) clinics and to investigate whether COVID-19 alters the pattern of the menstrual cycle. Material and Methods: This cross-sectional study was conducted on 275 healthcare professionals.
目的:SARS-CoV-2感染对生殖系统的影响尚不清楚。我们的目的是调查在2019冠状病毒病(COVID-19)诊所工作的医护人员的月经特征,并调查COVID-19是否改变了月经周期的模式。材料和方法:本横断面研究对275名卫生保健专业人员进行。
{"title":"Menstrual Cycle Characteristics of Healthcare Professionals Working at COVID-19 Pandemic Clinics","authors":"Sevcan Arzu Arınkan, F. Vural","doi":"10.5336/jcog.2021-82054","DOIUrl":"https://doi.org/10.5336/jcog.2021-82054","url":null,"abstract":"Objective: The impact of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection on the reproductive system is still not known. We aimed to investigate the menstrual characteristics of healthcare professionals employed in the coronavirus disease2019 (COVID-19) clinics and to investigate whether COVID-19 alters the pattern of the menstrual cycle. Material and Methods: This cross-sectional study was conducted on 275 healthcare professionals.","PeriodicalId":36268,"journal":{"name":"Journal of Clinical Obstetrics and Gynecology","volume":"1 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70761536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Comparison of Maternal-Fetal Outcome Following Operative Delivery: Omnicup Versus Malmstrom Metal Cup: Clinical Research 手术分娩后母胎结局的比较:Omnicup与Malmstrom金属杯:临床研究
IF 0.1 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2021-01-01 DOI: 10.5336/jcog.2021-82080
Gökhan Ünver, R. Karakuş, S. S. Karakus, Zafer Bütün, E. Ozkaya
{"title":"Comparison of Maternal-Fetal Outcome Following Operative Delivery: Omnicup Versus Malmstrom Metal Cup: Clinical Research","authors":"Gökhan Ünver, R. Karakuş, S. S. Karakus, Zafer Bütün, E. Ozkaya","doi":"10.5336/jcog.2021-82080","DOIUrl":"https://doi.org/10.5336/jcog.2021-82080","url":null,"abstract":"","PeriodicalId":36268,"journal":{"name":"Journal of Clinical Obstetrics and Gynecology","volume":"1 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70761606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnostic Profile of Corpus Callosum Anomalies at a Tertiary Center: A Retrospective Cross-sectional Study 三级中心胼胝体异常的诊断概况:回顾性横断面研究
IF 0.1 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2021-01-01 DOI: 10.5336/jcog.2021-81985
Z. Özköse, Süleyman Cemil Oğlak, Mustafa Behram, Fatma Ölmez, Ayşegül Bestel, S. S. Çaypinar, I. Ozdemir
ABS TRACT Objective: This study aimed to define the frequency and type of additional accompanying anomalies in cases with various anomalies of the corpus callosum (ACCs) in our tertiary center in the last 8 years. Material and Methods: This retrospective cross-sectional study included the data of 152 cases of prenatally diagnosed ACCs in a tertiary referral center between October 2012 and November 2020. We evaluated central nervous system and other organ system structural abnormalities, chromosomal abnormalities, and syndromes accompanying in non-isolated forms. Results: During the study period, a total of 152 cases with callosal anomaly were diagnosed throughout the study course in a population of 117,450 live births, resulting in an overall prevalence of 12.9 per 10,000 live births. Of the 152 cases ascer-tained, 105 (69%) were total agenesis, 38 (25%) were partial agenesis, and 9 (6%) were hypoplasia of the corpus callosum. Of these 152 cases, 80 (52.6%) had isolated ACC and the remaining 72 (47.4%) cases had at least one associated anomaly, including chromosomal anomalies, recognized syndromes, and multiple congenital abnormalities. Conclusion: ACCs are clinically and etiologically heterogeneous, and prenatal diagnosis is possible. Even in isolated cases, the neurodevelopmental prognosis is uncertain and mostly associated with other structural abnormalities, chromosomal and genetic diseases. Due to the underlying etiological cause, accompanying additional anomalies and un- certainty regarding developmental outcomes, chromosomal, syndromic, and additional structural disorders may be clues in antenatal ultrasonographic observation in ACC cases should be investigated with the more detailed sonographic examination and genetic tests.
目的:本研究旨在确定近8年来我院三级中心胼胝体(ACCs)各种异常病例的额外伴随异常的频率和类型。材料和方法:本回顾性横断面研究包括2012年10月至2020年11月在三级转诊中心进行的152例产前诊断的acc病例的数据。我们评估了中枢神经系统和其他器官系统结构异常、染色体异常以及非孤立形式的综合征。结果:在研究期间,在117,450名活产婴儿中,共有152例胼胝体异常被诊断出来,总体患病率为每10,000名活产婴儿12.9例。在152例确诊病例中,完全发育不全105例(69%),部分发育不全38例(25%),胼胝体发育不全9例(6%)。在这152例病例中,80例(52.6%)有孤立性ACC,其余72例(47.4%)至少有一种相关异常,包括染色体异常、公认综合征和多种先天性异常。结论:ACCs具有临床和病因异质性,产前诊断是可能的。即使在个别病例中,神经发育预后也不确定,而且大多与其他结构异常、染色体和遗传疾病有关。由于潜在的病因,伴随的其他异常和发育结局的不确定性,染色体,综合征和其他结构障碍可能是产前超声观察ACC病例的线索,应通过更详细的超声检查和基因检测进行调查。
{"title":"Diagnostic Profile of Corpus Callosum Anomalies at a Tertiary Center: A Retrospective Cross-sectional Study","authors":"Z. Özköse, Süleyman Cemil Oğlak, Mustafa Behram, Fatma Ölmez, Ayşegül Bestel, S. S. Çaypinar, I. Ozdemir","doi":"10.5336/jcog.2021-81985","DOIUrl":"https://doi.org/10.5336/jcog.2021-81985","url":null,"abstract":"ABS TRACT Objective: This study aimed to define the frequency and type of additional accompanying anomalies in cases with various anomalies of the corpus callosum (ACCs) in our tertiary center in the last 8 years. Material and Methods: This retrospective cross-sectional study included the data of 152 cases of prenatally diagnosed ACCs in a tertiary referral center between October 2012 and November 2020. We evaluated central nervous system and other organ system structural abnormalities, chromosomal abnormalities, and syndromes accompanying in non-isolated forms. Results: During the study period, a total of 152 cases with callosal anomaly were diagnosed throughout the study course in a population of 117,450 live births, resulting in an overall prevalence of 12.9 per 10,000 live births. Of the 152 cases ascer-tained, 105 (69%) were total agenesis, 38 (25%) were partial agenesis, and 9 (6%) were hypoplasia of the corpus callosum. Of these 152 cases, 80 (52.6%) had isolated ACC and the remaining 72 (47.4%) cases had at least one associated anomaly, including chromosomal anomalies, recognized syndromes, and multiple congenital abnormalities. Conclusion: ACCs are clinically and etiologically heterogeneous, and prenatal diagnosis is possible. Even in isolated cases, the neurodevelopmental prognosis is uncertain and mostly associated with other structural abnormalities, chromosomal and genetic diseases. Due to the underlying etiological cause, accompanying additional anomalies and un- certainty regarding developmental outcomes, chromosomal, syndromic, and additional structural disorders may be clues in antenatal ultrasonographic observation in ACC cases should be investigated with the more detailed sonographic examination and genetic tests.","PeriodicalId":36268,"journal":{"name":"Journal of Clinical Obstetrics and Gynecology","volume":"1 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70761477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Should All Abortion Materials Be Sent for Histopathological Evaluation? 所有流产材料都应该送去做组织病理学评估吗?
IF 0.1 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2021-01-01 DOI: 10.5336/jcog.2021-81117
M. Albayrak, I. Biyik, Mehmet Hüseyin Metineren, Y. Taşçı
{"title":"Should All Abortion Materials Be Sent for Histopathological Evaluation?","authors":"M. Albayrak, I. Biyik, Mehmet Hüseyin Metineren, Y. Taşçı","doi":"10.5336/jcog.2021-81117","DOIUrl":"https://doi.org/10.5336/jcog.2021-81117","url":null,"abstract":"","PeriodicalId":36268,"journal":{"name":"Journal of Clinical Obstetrics and Gynecology","volume":"1 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70761621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The Prevalence and Associated Factors of Fear of Childbirth Among Pregnant Adolescents in Turkey: A Cross-Sectional Study 土耳其怀孕青少年害怕分娩的患病率及相关因素:一项横断面研究
IF 0.1 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2021-01-01 DOI: 10.5336/jcog.2021-86477
Fatma Ölmez, Süleyman Cemil Oğlak
{"title":"The Prevalence and Associated Factors of Fear of Childbirth Among Pregnant Adolescents in Turkey: A Cross-Sectional Study","authors":"Fatma Ölmez, Süleyman Cemil Oğlak","doi":"10.5336/jcog.2021-86477","DOIUrl":"https://doi.org/10.5336/jcog.2021-86477","url":null,"abstract":"","PeriodicalId":36268,"journal":{"name":"Journal of Clinical Obstetrics and Gynecology","volume":"1 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70762045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effect of Estrogen and Progesterone Receptor Status on the Prognosis of Endometrioid Type Endometrial Cancer: Retrospective Study 雌激素和孕激素受体状态对子宫内膜样型子宫内膜癌预后影响的回顾性研究
IF 0.1 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2021-01-01 DOI: 10.5336/jcog.2021-81692
İrem Alyazıcı Küçükyıldız, A. Yanik
ABS TRACT Objective: Endometrioid-type endometrial cancer (EC) is the most common histological type of EC, and generally has good survival if diagnosed during the early stages. While tumour grade, stage and lymph node invasion are known to affect survival in these patients, the prognostic significance of steroid receptor status remains unclear. The present study aimed to determine the effect of estrogen and progesterone receptor (ER and PR, respectively) status and its relationship with other prognostic factors in endometrioid-type EC. Material and Methods: Data from 152 patients who underwent surgery at the same centre between 2009 and 2019 were retrospectively evaluated. Histological characteristics of tumours were determined using the original pathology reports, and stage, grade and lymph node involvement of tumours were compared with ER and PR status. The relationship between ER and PR status and preoperative serum cancer antigen 125 and albumin levels were also investigated. Results: When the results of our study were examined, it was revealed that 114 patients had Grade I tumor and 118 had International Federation of Gynecology and Obstetrics Stage I tumor and 34 patients had ER and PR negativity. In our study, a dependence was found between both ER and PR status and pelvic lymph node involvement. It was found that the possibility of pelvic lymph node involvement increases in both hormone receptor negativity. Conclusion: This study reports that the patients with pelvic lymph node involvement, which is a prognostic factor in EC, may experience more frequent ER and PR negativity. However, its effects on survival remain unclear.
目的:子宫内膜样型子宫内膜癌(EC)是最常见的组织学类型,如果在早期诊断,通常具有良好的生存率。虽然已知肿瘤分级、分期和淋巴结侵袭会影响这些患者的生存,但类固醇受体状态的预后意义尚不清楚。本研究旨在探讨雌激素和孕激素受体(ER和PR)状态在子宫内膜样型EC中的影响及其与其他预后因素的关系。材料和方法:对2009年至2019年在同一中心接受手术的152例患者的数据进行回顾性评估。根据原始病理报告确定肿瘤的组织学特征,并将肿瘤的分期、分级和淋巴结受累情况与ER和PR状态进行比较。研究ER和PR水平与术前血清癌抗原125和白蛋白水平的关系。结果:我们的研究结果显示,114例患者为I级肿瘤,118例为国际妇产联合会I期肿瘤,34例ER和PR阴性。在我们的研究中,发现ER和PR状态与盆腔淋巴结受累之间存在依赖关系。发现盆腔淋巴结受累的可能性在激素受体阴性的情况下增加。结论:本研究报告盆腔淋巴结受累是EC的预后因素之一,患者可能更频繁出现ER和PR阴性。然而,它对生存的影响尚不清楚。
{"title":"The Effect of Estrogen and Progesterone Receptor Status on the Prognosis of Endometrioid Type Endometrial Cancer: Retrospective Study","authors":"İrem Alyazıcı Küçükyıldız, A. Yanik","doi":"10.5336/jcog.2021-81692","DOIUrl":"https://doi.org/10.5336/jcog.2021-81692","url":null,"abstract":"ABS TRACT Objective: Endometrioid-type endometrial cancer (EC) is the most common histological type of EC, and generally has good survival if diagnosed during the early stages. While tumour grade, stage and lymph node invasion are known to affect survival in these patients, the prognostic significance of steroid receptor status remains unclear. The present study aimed to determine the effect of estrogen and progesterone receptor (ER and PR, respectively) status and its relationship with other prognostic factors in endometrioid-type EC. Material and Methods: Data from 152 patients who underwent surgery at the same centre between 2009 and 2019 were retrospectively evaluated. Histological characteristics of tumours were determined using the original pathology reports, and stage, grade and lymph node involvement of tumours were compared with ER and PR status. The relationship between ER and PR status and preoperative serum cancer antigen 125 and albumin levels were also investigated. Results: When the results of our study were examined, it was revealed that 114 patients had Grade I tumor and 118 had International Federation of Gynecology and Obstetrics Stage I tumor and 34 patients had ER and PR negativity. In our study, a dependence was found between both ER and PR status and pelvic lymph node involvement. It was found that the possibility of pelvic lymph node involvement increases in both hormone receptor negativity. Conclusion: This study reports that the patients with pelvic lymph node involvement, which is a prognostic factor in EC, may experience more frequent ER and PR negativity. However, its effects on survival remain unclear.","PeriodicalId":36268,"journal":{"name":"Journal of Clinical Obstetrics and Gynecology","volume":"1 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70761866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of Clinical Obstetrics and Gynecology
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1