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Radiation therapists’ perspectives on artificial intelligence: Insights from a single institution on Improving effectiveness and educational supports 放射治疗师对人工智能的看法:来自单一机构对提高有效性和教育支持的见解。
Q1 Nursing Pub Date : 2025-01-05 DOI: 10.1016/j.tipsro.2025.100300
Caroline Marr , Yat Tsang

Introduction

In recent years, artificial intelligence (AI) technology has played an evolving role in radiation science, influencing the clinical practice of radiation therapists. This study aimed to explore the knowledge, attitude, clinical applications, and learning needs from the perspective of radiation therapists.

Materials and Methods

This study used a cross-sectional online survey with a population of radiation therapists from a single institution. The survey was developed iteratively and was based on past literature. The questions were constructed to measure perception using four themes: knowledge of AI, perceived utilization, job impact, clinical applications, learning needs, and educational support. The data was analyzed using descriptive statistics according to the key themes.

Results

Between 22nd December 2023 and 17th January 2024, 74 radiation therapists completed the survey. The majority (55.4 %) were 44 years or older (Baby Boomers and Generation X). Additionally, 37.8 % rated their knowledge of AI as none or limited, but 93.2 % expressed interest in learning more about AI. Many (79.7 %) perceived AI not to be fully used in radiation therapy but has increased its effectiveness in image registration, reconstruction, and contouring. With the increasing use of AI in healthcare, 96.0 % feel that AI may affect their role, and 82.4 % believe it may impact their job satisfaction. Educational supports indicated to be the most advantageous for their job were online modules (36.5 %) and in-person workshops (35.1 %).

Conclusion

Exploring the perspectives of radiation therapists has shown a strong interest in learning about AI and its role in radiation therapy. This information can help in understanding how to develop tailored strategies to mitigate potential barriers, leading to the successful implementation of AI in clinical radiation therapy practice.
导读:近年来,人工智能(AI)技术在放射科学中发挥着不断发展的作用,影响着放射治疗师的临床实践。本研究旨在探讨放射治疗师的知识、态度、临床应用和学习需求。材料和方法:本研究对来自单一机构的放射治疗师进行了横断面在线调查。这项调查是根据过去的文献反复进行的。这些问题是通过四个主题来衡量感知的:人工智能知识、感知利用、工作影响、临床应用、学习需求和教育支持。根据关键主题,采用描述性统计方法对数据进行分析。结果:在2023年12月22日至2024年1月17日期间,74名放射治疗师完成了调查。大多数人(55.4%)年龄在44岁或以上(婴儿潮一代和X一代)。此外,37.8%的人认为他们对人工智能一无所知或了解有限,但93.2%的人表示有兴趣更多地了解人工智能。许多人(79.7%)认为人工智能并没有完全用于放射治疗,但它在图像配准、重建和轮廓方面的有效性有所提高。随着人工智能在医疗保健领域的应用越来越多,96.0%的人认为人工智能可能会影响他们的角色,82.4%的人认为人工智能可能会影响他们的工作满意度。对他们的工作最有利的教育支持是在线模块(36.5%)和面对面的研讨会(35.1%)。结论:探索放射治疗师的观点显示出对学习人工智能及其在放射治疗中的作用的强烈兴趣。这些信息有助于了解如何制定量身定制的策略来减轻潜在的障碍,从而在临床放射治疗实践中成功实施人工智能。
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引用次数: 0
Integrating knowledge-based planning and noncoplanar oblique VMAT arcs: A study of dose to the heart and immune cells in thoracic radiotherapy 整合基于知识的计划和非共面倾斜VMAT弧线:胸部放射治疗对心脏和免疫细胞的剂量研究。
Q1 Nursing Pub Date : 2025-01-05 DOI: 10.1016/j.tipsro.2025.100301
Brennan Diedrich, Justin Roper, Benjamin Hopkins, Sibo Tian, Shadab Momin, Eduard Schreibmann, Aparna H. Kesarwala, Kirk Luca

Background

Recent patient studies have linked higher immune cell doses with worse quality of life and survival. For thoracic radiotherapy, heart dose is a major contributor to the effective dose to immune cells (EDIC).

Purpose

This study investigates heart and immune cell doses for plans optimized using a cardiac-sparing knowledge-based planning (KBP) model and the impact of carefully crafted beam geometry.

Methods

Sixteen stage III NSCLC patients previously treated to 60 Gy in 30 fractions using coplanar VMAT arcs were replanned using a cardiac-sparing KBP model with either the clinical field arrangement or noncoplanar oblique arcs that prioritize heart sparing. The cardiac-sparing KBP model consisted of fifteen substructures, all of which were used during optimization. All plans were normalized to 95% PTV coverage at 60 Gy. Statistical significance was assessed for EDIC (Jin Model), along with mean doses to the heart, lungs, body, and both the mean dose and D0.03 cc values for cardiac substructures, using the Wilcoxon signed-rank test.

Results

Compared to the clinically treated plans with the same beam geometry, cardiac-sparing KBP reduced mean heart dose from 8.50 Gy to 4.09 Gy and EDIC from 4.27 Gy to 3.81 Gy (p < 0.001). For the novel arcs, the mean heart dose was reduced to 3.70 Gy, significantly lower than KBP with clinical beam geometry (p = 0.001). EDIC, however, was equivalent. No statistically meaningful differences were observed for the remaining organs at risk, and all plans met institutional planning goals.

Conclusion

Cardiac-sparing RapidPlan is a valuable tool for reducing heart dose and lowering EDIC in NSCLC patients. Additional heart sparing is possible by strategically crafting noncoplanar oblique beams to minimize heart dose.
背景:最近的患者研究表明,较高的免疫细胞剂量与较差的生活质量和生存率有关。目的:本研究调查了使用保心知识规划(KBP)模型优化计划的心脏和免疫细胞剂量,以及精心设计的射束几何形状的影响:16例III期NSCLC患者之前曾接受过共面VMAT弧线治疗,每30个小节治疗60Gy,研究人员使用一个心脏保护KBP模型对其进行了重新规划,该模型既可以采用临床领域的安排,也可以采用优先保护心脏的非共面斜弧线。心脏保全 KBP 模型由 15 个子结构组成,优化过程中使用了所有这些子结构。所有计划均归一化为 95% PTV 覆盖率,60 Gy。使用Wilcoxon符号秩检验评估了EDIC(Jin模型)以及心脏、肺部、全身的平均剂量,以及心脏亚结构的平均剂量和D0.03 cc值的统计意义:结果:与具有相同射束几何形状的临床治疗计划相比,保心KBP将心脏的平均剂量从8.50 Gy减少到4.09 Gy,EDIC从4.27 Gy减少到3.81 Gy(p 结论:保心KBP计划可将心脏的平均剂量从8.50 Gy减少到4.09 Gy,EDIC从4.27 Gy减少到3.81 Gy:心脏保护 RapidPlan 是减少 NSCLC 患者心脏剂量和降低 EDIC 的重要工具。通过策略性地设计非共面斜束,最大限度地减少心脏剂量,还可以进一步保护心脏。
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引用次数: 0
Global professional issues in radiation therapy: Collaboration, adaptation and innovation 放射治疗的全球专业问题:合作、适应和创新
Q1 Nursing Pub Date : 2024-12-31 DOI: 10.1016/j.tipsro.2024.100298
Yolanda Surjan , Sandra Ndarukwa
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引用次数: 0
Proton beam therapy image-guided radiotherapy training for RTTs – Experience from a single institution rtt的质子束治疗图像引导放射治疗培训-来自单一机构的经验。
Q1 Nursing Pub Date : 2024-12-19 DOI: 10.1016/j.tipsro.2024.100299
Jannath Shirin Kottakunnan , Samaneh Shoraka , Amy Dodd , Maria Kilkenny , Sarah Petty , Kathryn Osborn , Amanda Webster
This study investigates whether an Image-Guided Radiation Therapy (IGRT) workbook and Cone Beam Computed Tomography (CBCT) case studies enhances Radiation Therapists’ (RTTs) confidence analysing Proton Beam Therapy (PBT) CBCTs. An 11-participant questionnaire-based study was conducted to assess pre- and post-training confidence. Prior to training, RTTs exhibited higher confidence in photon CBCT decision-making over proton CBCT, highlighting the need for PBT-specific IGRT training, irrespective of prior photon experience. After completing the PBT IGRT workbook and case studies, RTTs experienced increased confidence in analysing PBT CBCTs. The workbook was particularly beneficial for junior RTTs, while experienced staff desired clearer guidance and real-life scenarios. The results show the IGRT workbook and CBCT case studies enhance RTTs’ confidence in PBT CBCT analysis. PBT departments should consider these results for RTT led IGRT. Future work could involve adjusting training to account for participants’ prior IGRT experience and conducting larger-scale studies to validate our results.
本研究探讨了图像引导放射治疗(IGRT)工作手册和锥束计算机断层扫描(CBCT)案例研究是否增强了放射治疗师(rtt)对质子束治疗(PBT) CBCT的信心。一项11人参与的基于问卷的研究进行了评估培训前和培训后的信心。在训练之前,与质子CBCT相比,rtt在光子CBCT决策方面表现出更高的信心,这突出了pbt特异性IGRT训练的必要性,而不管之前的光子经验如何。在完成PBT IGRT工作手册和案例研究后,rtt在分析PBT cbct方面的信心增加了。工作手册对初级rtf特别有益,而经验丰富的工作人员则希望得到更清晰的指导和真实的场景。结果表明,IGRT工作手册和CBCT案例研究增强了rtt对PBT CBCT分析的信心。PBT部门在RTT引导IGRT时应考虑这些结果。未来的工作可能包括调整培训以考虑参与者先前的IGRT经验,并进行更大规模的研究来验证我们的结果。
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引用次数: 0
Comparative evaluation of two dose-volume histogram prediction tools for treatment planning: Treatment planning quality and dose verification accuracy 两种治疗计划剂量-体积直方图预测工具的比较评价:治疗计划质量和剂量验证准确性。
Q1 Nursing Pub Date : 2024-12-13 DOI: 10.1016/j.tipsro.2024.100297
Shoma Nakano , Motoharu Sasaki , Yuji Nakaguchi , Takeshi Kamomae , Kanako Sakuragawa , Yuto Yamaji , Hitoshi Ikushima

Purpose

This study aims to compare treatment plans created using RapidPlan and PlanIQ for twelve patients with prostate cancer, focusing on dose uniformity, dose reduction to organs at risk (OARs), plan complexity, and dose verification accuracy. The goal is to identify the tool that demonstrates superior performance in achieving uniform target dose distribution and reducing OAR dose, while ensuring accurate dose verification.

Methods

Dose uniformity in the planning target volume, excluding the rectum, and dose reduction in the OARs (the rectum and bladder) were assessed. The validation included point-dose measurements with an ionization chamber dosimeter and gamma analysis of dose distributions. Monitor units were calculated to evaluate plan complexity.

Results

PlanIQ provided superior dose uniformity, with improvements in the dose homogeneity index compared with RapidPlan. RapidPlan was more effective in reducing OAR doses, particularly in the rectum, with significant reductions at various dose levels. Dose verification showed no significant differences between the two tools. However, PlanIQ showed a smaller mean difference between the calculated and measured doses and a slightly better dose distribution match with less variability than RapidPlan.

Conclusions

RapidPlan was more effective at reducing OAR doses, whereas PlanIQ achieved better dose uniformity and lower plan complexity. Both tools performed similarly in terms of dose verification accuracy, with PlanIQ showing a slight advantage in dose-distribution matching. The choice of planning tool depends on the primary treatment goal, whether it is to reduce the OAR doses or improve the target dose uniformity.
目的:本研究旨在比较RapidPlan和PlanIQ为12例前列腺癌患者制定的治疗方案,重点关注剂量均匀性、危及器官剂量减少(OARs)、方案复杂性和剂量验证准确性。目标是确定在实现均匀靶剂量分布和降低OAR剂量方面表现优异的工具,同时确保准确的剂量验证。方法:评估计划靶区(不包括直肠)的剂量均匀性和OARs(直肠和膀胱)的剂量减少情况。验证包括用电离室剂量计进行点剂量测量和剂量分布的伽马分析。计算监测单元以评估计划的复杂性。结果:PlanIQ提供了更好的剂量均匀性,与RapidPlan相比,剂量均匀性指数有所提高。RapidPlan在减少OAR剂量方面更有效,特别是在直肠,在不同剂量水平上都有显著的减少。剂量验证显示两种工具之间无显著差异。然而,与RapidPlan相比,PlanIQ显示计算剂量和测量剂量之间的平均差异较小,剂量分布匹配略好,变异性较小。结论:RapidPlan在降低OAR剂量方面更有效,而PlanIQ具有更好的剂量均匀性和更低的计划复杂性。两种工具在剂量验证精度方面表现相似,PlanIQ在剂量分布匹配方面显示出轻微的优势。计划工具的选择取决于主要治疗目标,是降低OAR剂量还是提高靶剂量均匀性。
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引用次数: 0
Illuminating the hidden cost: A systematic review of cognitive late effects regarding cancer-related fatigue in treated paediatric brain tumors 揭示隐藏的成本:一项关于治疗的儿童脑肿瘤患者癌症相关疲劳的认知晚期效应的系统综述。
Q1 Nursing Pub Date : 2024-12-09 DOI: 10.1016/j.tipsro.2024.100291
Ingrid Vethe Hernes , Amalie Jansdatter , Anita Nordsteien , Mathilde Haraldsen Normann

Objective

Globally, in 2022, 30,871 children were diagnosed with CNS-tumors. Many have been treated with radiotherapy, and a significant number suffer from chronic late effects, including fatigue. This study aims to investigate previous research on the impact of cancer-related fatigue for neurocognitive function that can be related to radiotherapy in patients who have undergone primary brain radiotherapy before the age of 18.

Methods

Conducted under PRISMA-S framework, this systematic review searched MEDLINE ALL (Ovid), EMBASE (Ovid), CINAHL (EBSCO), and PsycINFO (Ovid) for relevant studies. Criteria for inclusion were children under 18 who underwent radiotherapy for primary brain cancer, focusing on late cognitive side effects, published 2000–2023.

Results

From 4,067 records, 10 studies were included, examining Proton Radiation Therapy (n = 4), X-ray Radiation Therapy (n = 3), and their comparisons (n = 3). The studies used various cognitive tests, and late effects that emerged were neurocognitive functions and disorders, intellectual functioning, specific cognitive functions and daily life, social functioning, and performance. These themes can be encompassed by cancer-related fatigue.

Conclusions

The findings underscore critical need for more in-depth research to understand the health perception variations among children post-primary brain radiotherapy. Furthermore, detailed insights of treatment specifics, disease progression, target volume sizes, and doses to surrounding organs at risk are imperative.
目的:在全球范围内,2022年,30,871名儿童被诊断为中枢神经系统肿瘤。许多人接受了放射治疗,而且相当多的人患有慢性晚期症状,包括疲劳。本研究旨在调查18岁之前接受过初级脑放疗的患者的癌症相关性疲劳对神经认知功能的影响,该影响可能与放疗有关。方法:本系统综述在PRISMA-S框架下,检索MEDLINE ALL (Ovid)、EMBASE (Ovid)、CINAHL (EBSCO)和PsycINFO (Ovid)进行相关研究。纳入标准为18岁以下接受原发性脑癌放疗的儿童,重点关注晚期认知副作用,发表于2000-2023年。结果:从4067份记录中,纳入了10项研究,检查了质子放射治疗(n = 4),x射线放射治疗(n = 3)及其比较(n = 3)。这些研究使用了各种认知测试,出现的后期影响包括神经认知功能和障碍、智力功能、特定认知功能和日常生活、社会功能和表现。这些主题可以被癌症相关的疲劳所涵盖。结论:研究结果强调了对儿童原发性脑放疗后健康感知变化进行更深入研究的迫切需要。此外,详细了解治疗细节、疾病进展、靶体积大小和周围器官的风险剂量是必要的。
{"title":"Illuminating the hidden cost: A systematic review of cognitive late effects regarding cancer-related fatigue in treated paediatric brain tumors","authors":"Ingrid Vethe Hernes ,&nbsp;Amalie Jansdatter ,&nbsp;Anita Nordsteien ,&nbsp;Mathilde Haraldsen Normann","doi":"10.1016/j.tipsro.2024.100291","DOIUrl":"10.1016/j.tipsro.2024.100291","url":null,"abstract":"<div><h3>Objective</h3><div>Globally, in 2022, 30,871 children were diagnosed with CNS-tumors. Many have been treated with radiotherapy, and a significant number suffer from chronic late effects, including fatigue. This study aims to investigate previous research on the impact of cancer-related fatigue for neurocognitive function that can be related to radiotherapy in patients who have undergone primary brain radiotherapy before the age of 18.</div></div><div><h3>Methods</h3><div>Conducted under PRISMA-S framework, this systematic review searched MEDLINE ALL (Ovid), EMBASE (Ovid), CINAHL (EBSCO), and PsycINFO (Ovid) for relevant studies. Criteria for inclusion were children under 18 who underwent radiotherapy for primary brain cancer, focusing on late cognitive side effects, published 2000–2023.</div></div><div><h3>Results</h3><div>From 4,067 records, 10 studies were included, examining Proton Radiation Therapy (n = 4), X-ray Radiation Therapy (n = 3), and their comparisons (n = 3). The studies used various cognitive tests, and late effects that emerged were neurocognitive functions and disorders, intellectual functioning, specific cognitive functions and daily life, social functioning, and performance. These themes can be encompassed by cancer-related fatigue.</div></div><div><h3>Conclusions</h3><div>The findings underscore critical need for more in-depth research to understand the health perception variations among children post-primary brain radiotherapy. Furthermore, detailed insights of treatment specifics, disease progression, target volume sizes, and doses to surrounding organs at risk are imperative.</div></div>","PeriodicalId":36328,"journal":{"name":"Technical Innovations and Patient Support in Radiation Oncology","volume":"33 ","pages":"Article 100291"},"PeriodicalIF":0.0,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11699426/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142932896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Case report: Clinical workflow considerations for treating soft-tissue sarcoma on a 1.5-T MR-Linac 病例报告:在1.5 t MR-Linac上治疗软组织肉瘤的临床工作流程考虑。
Q1 Nursing Pub Date : 2024-12-07 DOI: 10.1016/j.tipsro.2024.100296
Gye Won Choi, Gary A. Eastwick, Leonard H. Kim
We present specific issues that arose when using a 1.5-Tesla MR-Linac to treat a series of 4 soft-tissue sarcoma (STS) patients. These issues arose from the combination of typical STS attributes (long, off-axis target) and MR-Linac design-specific limitations on field size and patient positioning. Despite the availability of on-line plan adaptation, STS patients were more efficiently treated after workflow changes to improve patient selection and immobilization. Other issues arising from off-axis STS target locations: geometric distortion of MR images and patient-specific QA, are discussed.
我们提出了使用1.5特斯拉MR-Linac治疗一系列4例软组织肉瘤(STS)患者时出现的具体问题。这些问题是由典型的STS属性(长,离轴靶标)和MR-Linac设计对视野大小和患者定位的特定限制共同引起的。尽管有在线计划调整,但在工作流程改变以改善患者选择和固定后,STS患者得到了更有效的治疗。本文还讨论了由离轴STS靶位置引起的其他问题:MR图像的几何畸变和患者特异性QA。
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引用次数: 0
Advanced practice radiation therapist led vaginal vault brachytherapy: An evaluation of efficiency and effectiveness of service delivery 高级实践放射治疗师引导阴道穹窿近距离治疗:服务交付效率和效果的评估
Q1 Nursing Pub Date : 2024-12-01 DOI: 10.1016/j.tipsro.2024.100289
Rhona Goodwin

Aims

An advanced practice radiation therapist (APRT) role in vaginal vault brachytherapy (VBT) was first introduced in 2015. The aim of this manuscript was to clarify how the introduction of an APRT can improve efficiencies within service delivery while maintaining non inferior clinical outcomes of recurrence.

Materials and methods

This was a single-centred retrospective comparative service evaluation of stage 1 endometrial cancer patients treated with postoperative high dose rate VBT alone. Sixty patients in total were included in the evaluation. They were divided into two equal groups of ‘before’ and ‘after’ based on the introduction of the APRT-led role and changes made to treatment processes. Quantitative analysis of waiting times from surgery to adjuvant VBT (weeks), duration of day one treatment procedure (minutes), rate of isolated vaginal recurrence and loco regional recurrence (vaginal and pelvic) were compared between the groups.

Results

The mean time from surgery to treatment between the ‘before’ and ‘after’ groups was 13.1 and 9.1 weeks respectively. The mean time for day one treatment procedure was 91 min in the ‘before’ group and 59 min in the ‘after’ group. Vaginal free recurrence (VFR) was 100 % for both groups..

Conclusion

An APRT led vaginal vault service, with learnt role extension, allows for a more efficient and effective service delivery.
AimsAn高级实践放射治疗师(APRT)在阴道穹窿近距离治疗(VBT)中的作用于2015年首次推出。本文的目的是阐明APRT的引入如何提高服务提供的效率,同时保持复发的非劣等临床结果。材料和方法本研究是一项单中心回顾性比较服务评估1期子宫内膜癌患者术后单独接受高剂量率VBT治疗。共有60例患者被纳入评估。根据aprt主导作用的引入和治疗过程的变化,他们被分为“之前”和“之后”两组。定量分析从手术到辅助VBT的等待时间(周)、第一天治疗过程的持续时间(分钟)、孤立性阴道复发率和局部区域复发率(阴道和盆腔)。结果术前组和术后组从手术到治疗的平均时间分别为13.1周和9.1周。“治疗前”组治疗第一天的平均时间为91分钟,“治疗后”组为59分钟。结论以APRT为主导的阴道拱顶服务,学习角色的延伸,使服务提供更加高效和有效。
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引用次数: 0
Can Tho oncology (Việt Nam) hospital radiotherapy department: A Snapshot of current and future practice 可拓肿瘤科(Việt南)医院放疗科:当前和未来实践的快照
Q1 Nursing Pub Date : 2024-12-01 DOI: 10.1016/j.tipsro.2024.100292
Tran Thanh Phong, Vo Van Kha, Le Thi Den
Can Tho City Oncology Hospital was established on September 28, 2007, by the People’s Committee of Can Tho City. The Can Tho City Oncology Hospital has been in operation for 17 years and has over time become a reliable place for the provision of oncological patient services and treatment for Can Tho citizens and the Mekong Delta area. The Hospital includes approximately 400 patient beds, 9 clinical departments, 5 paraclinical departments (radiology, pathology etc), and 8 functional rooms (customer care epartment, admissions, discharge office, finance and accounting division,). The Radiotherapy Department is a busy and important part of the Hospital and plays an important role in cancer patient treatment.
Introducing the current situation, challenges and future plans for the Radiotherapy Department in Can Tho Oncology Hospital, Việt Nam.
芹苴市肿瘤医院由芹苴市人民委员会于2007年9月28日成立。芹苴市肿瘤医院已经运营了17年,随着时间的推移,它已成为为芹苴市民和湄公河三角洲地区提供肿瘤患者服务和治疗的可靠场所。医院拥有近400张病床,9个临床科室,5个临床辅助科室(放射科、病理科等),8个功能室(客户服务部、入院、出院处、财务科、)。放疗科是医院的一个繁忙而重要的组成部分,在肿瘤患者的治疗中起着重要的作用。介绍灿苴肿瘤医院放射治疗科的现况、挑战及未来计划Việt南。
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引用次数: 0
Benchmarking and performance evaluation of a novel deformable image registration software for radiotherapy CT images 一种用于放疗CT图像的新型可变形图像配准软件的基准测试和性能评估。
Q1 Nursing Pub Date : 2024-12-01 DOI: 10.1016/j.tipsro.2024.100295
Shorug S. Alshammari , Sridhar Yaddanapudi , Blaž Kušnik , Rok Ivančič , Kristjan Anderle , Jonathan G. Li , Keith M. Furutani , Chris J. Beltran , Bo Lu

Purpose

We evaluated and benchmarked a novel deformable image registration (DIR) software functionality (DirOne, Cosylab d.d., Ljubljana, Slovenia) by comparing it to two commercial systems, MIM and VelocityAI, following AAPM task group 132 (TG-132) guidelines.

Methods

Three publicly available datasets were used for evaluation. The first dataset includes primary and deformed phantom images for a male pelvis. The second, from DIR-Lab, contains ten sets of 4D CT thoracic scans. The third dataset, from the DIR Evaluation Project (DIREP), includes ten head and neck CTs. VelocityAI and MIM served as benchmarks to assess DirOne’s performance. Target registration error (TRE), dice similarity coefficient (DSC), and mean distance to agreement (MDA) were the evaluation metrics.

Results

For TRE, the average results for DirOne, MIM, and VelocityAI were 3.3 ± 3.1 mm, 2.7 ± 3.7 mm, and 3.4 ± 2.4 mm, respectively. For DSC, DirOne achieved 0.96 ± 0.02, MIM 0.98 ± 0.02, and VelocityAI 0.98 ± 0.01 across the first and second datasets. In the DIREP dataset, DirOne achieved 0.73 ± 0.34 for MDA and 0.91 ± 0.03 for DSC; MIM achieved 0.54 ± 0.36 and 0.93 ± 0.02, and VelocityAI 0.93 ± 0.38 and 0.90 ± 0.03.

Conclusion

The novel DIR software demonstrated clinically acceptable accuracy compared to other commercial systems, supporting its potential use in radiotherapy treatment planning applications such as automatic image segmentation, 4D segmentation propagation, and dose warping.
目的:我们根据AAPM任务组132 (TG-132)指南,将一种新的可变形图像配准(DIR)软件功能(DirOne, Cosylab博士,卢布尔雅那,斯洛文尼亚)与两个商业系统MIM和VelocityAI进行比较,评估并对其进行基准测试。方法:使用三个公开可用的数据集进行评估。第一个数据集包括男性骨盆的原始和变形幻象图像。第二份来自DIR-Lab,包含十组4D CT胸部扫描。第三个数据集来自DIR评估项目(DIREP),包括10个头颈部ct。VelocityAI和MIM作为评估DirOne性能的基准。目标配准误差(TRE)、骰子相似系数(DSC)和平均一致距离(MDA)为评价指标。结果:对于TRE, DirOne、MIM和VelocityAI的平均结果分别为3.3±3.1 mm、2.7±3.7 mm和3.4±2.4 mm。对于DSC, DirOne在第一和第二数据集上实现了0.96±0.02,MIM为0.98±0.02,VelocityAI为0.98±0.01。在DIREP数据集中,DirOne的MDA和DSC分别达到0.73±0.34和0.91±0.03;MIM分别为0.54±0.36和0.93±0.02,VelocityAI分别为0.93±0.38和0.90±0.03。结论:与其他商业系统相比,新型DIR软件具有临床可接受的准确性,支持其在放射治疗计划应用中的潜在应用,如自动图像分割,4D分割传播和剂量翘曲。
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引用次数: 0
期刊
Technical Innovations and Patient Support in Radiation Oncology
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