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Daily intake of a lycopene-rich juice is associated with reductions in inflammatory markers but not increases in skin carotenoids in a pilot study among participants with obesity. 在一项针对肥胖参与者的初步研究中,每天摄入富含番茄红素的果汁与炎症标志物的减少有关,但与皮肤类胡萝卜素的增加无关。
IF 2.2 Q3 NUTRITION & DIETETICS Pub Date : 2025-12-19 DOI: 10.1186/s40795-025-01222-y
Stephanie B Jilcott Pitts, Qiang Wu, Melissa N Laska, Elizabeth Gates, Megumi H Seese, Katelyn E Senkus, Santiago Carrero Longlax, Alexandra Portillo-Varela, Andrew R DiNardo, Nancy E Moran
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引用次数: 0
Evaluation of the iron, zinc, and folic acid stability in fortified wheat flour storage and its impact on quality indicators. 强化小麦粉贮存中铁、锌、叶酸稳定性评价及其对品质指标的影响
IF 2.2 Q3 NUTRITION & DIETETICS Pub Date : 2025-12-18 DOI: 10.1186/s40795-025-01213-z
Abebe Bitew Zegeye, Abebe Ayelign, Alebachew Habte Gezmu, Chere Tadesse, Kelemua Tesfaye, Misganaw Andualem, Zeweter Abebe Sime

The fortification of wheat flour with micronutrients is regarded as an effective strategy for preventing micronutrient deficits in the general population. Therefore, this study was intended to evaluate the storage stability of iron, zinc, and folic acid in fortified wheat flour, as well as the overall quality properties of flour during storage. Wheat flour was fortified (with zinc oxide 80 mg/kg, iron sodium EDTA 30 mg/kg, and 2 mg/kg folic acid) and stored over a 6-month period in a polyethylene bag. Iron was analyzed based on the AOAC official method 944.02, dry ash technique, ultraviolet-visible reading spectrophotometer. Zinc was determined using micro plasma atomic emission spectroscopy and the folic acid content was determined using HPLC. Micronutrients remain stable during storage. Zinc and iron showed no significant losses at stored temperatures. The percentages of zinc and iron retention ranged from 96.1 to 100%; however, folic acid showed significant losses, and the percentages of retention ranged from 68.5 to 87.8%. Peroxide value was increased from 0 to 0.1484milliequivalents per kilogram (mEq/kg) of fat during storage, and pH decreased from 6.23 to 5.38 during the period of six months of storage. The moisture content did not exhibit any significant changes. In conclusion, fortification of iron, zinc, and folic acid in wheat flour remains stable during storage for six months. Fortification is a good technique to lower population micronutrient deficits.

在小麦粉中添加微量营养素被认为是预防普通人群微量营养素缺乏的有效策略。因此,本研究旨在评价强化小麦粉中铁、锌和叶酸的储存稳定性,以及面粉在储存期间的整体品质特性。小麦粉被强化(氧化锌80 mg/kg, EDTA铁钠30 mg/kg,叶酸2 mg/kg),并在聚乙烯袋中储存6个月。采用AOAC官方方法944.02、干灰法、紫外可见读数分光光度计对铁进行了分析。采用微等离子体原子发射光谱法测定锌含量,高效液相色谱法测定叶酸含量。微量营养素在贮存期间保持稳定。锌和铁在储存温度下没有明显的损失。锌和铁的保留率为96.1 ~ 100%;然而,叶酸损失明显,保留率为68.5% ~ 87.8%。过氧化值在储存期间从0增加到0.1484毫当量/公斤(mEq/kg), pH在储存6个月期间从6.23下降到5.38。水分含量没有明显变化。综上所述,小麦面粉中铁、锌和叶酸的强化在储存6个月期间保持稳定。营养强化是降低人群微量营养素缺乏症的好方法。
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引用次数: 0
Relationship and predictive value of controlling nutritional status score and serum vitamin level with coronary heart disease in young and middle-aged adults. 控制营养状况评分及血清维生素水平与中青年冠心病的关系及预测价值
IF 2.2 Q3 NUTRITION & DIETETICS Pub Date : 2025-12-18 DOI: 10.1186/s40795-025-01220-0
Jie Deng, Xiaoming Liu, Haining Liu, Wei Lu
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引用次数: 0
The impact of nutritional risk on the progression of COVID-19: a retrospective study. 营养风险对COVID-19进展的影响:一项回顾性研究
IF 2.2 Q3 NUTRITION & DIETETICS Pub Date : 2025-12-13 DOI: 10.1186/s40795-025-01219-7
Min Xu, Runzhu Wang, Hong Zhao, Jiadan Fu, Xia Yu, Huafen Wang
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引用次数: 0
Prevalence of stunting, wasting, and underweight among children aged 6 to 59 months and adolescents in pastoral and semi-pastoral areas of Ethiopia: a systematic review and meta-analysis. 埃塞俄比亚牧区和半牧区6至59个月儿童和青少年中发育迟缓、消瘦和体重不足的患病率:一项系统回顾和荟萃分析
IF 2.2 Q3 NUTRITION & DIETETICS Pub Date : 2025-12-12 DOI: 10.1186/s40795-025-01210-2
Zekarias Markos, Yegle Asrat Tekletsadik, Ayenew Kassegn, Esubalew Muluneh Aligaz
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引用次数: 0
Norwegian food system actors' perspectives on participating in a cross-sector research partnership: a qualitative study. 挪威食品系统参与者参与跨部门研究伙伴关系的观点:一项定性研究。
IF 2.2 Q3 NUTRITION & DIETETICS Pub Date : 2025-12-10 DOI: 10.1186/s40795-025-01192-1
Anne Lene Løvhaug, Lisa Garnweidner-Holme, Laura Terragni, Arnfinn Helleve

Background: Cross-sector partnerships are governance models that are increasingly used in policy, research and practice to address food systems challenges including unhealthy diets. Despite ongoing debates about their value, especially in research, there is limited knowledge on the experiences of participating in these partnerships. This study is set in Norway, a country with tradition for cross-sector collaboration. We examine the Norwegian cross-sector research partnership NewTools to explore participants' perspectives in an early project stage. The partnership comprises 28 actors from research institutions, food industry, civil society and government agencies, and aims to develop two food profiling models: one for nutrition and one for environmental and social sustainability. This study can help identify initial factors that can influence nutrition-related cross-sector collaboration processes.

Methods: We conducted qualitative interviews with 17 NewTools-participants in 2022. Interviews were analyzed with reflexive thematic analysis.

Results: Five themes were identified: (i) "The importance of being in the room" illustrated participants views on the benefits of cross-sector collaboration, including sharing expertise and influencing project outcomes. (ii) "Divergent expectations towards collaboration and project aims" reflected varying expectations towards partner involvement and the project outcomes among participants. (iii) "Viewpoints towards food profiling systems" highlighted differing viewpoints on two food profiling models to be developed, with more skeptical views towards the nutrition profiling model. (iv) "Power asymmetries and mistrust" suggested potential tensions and some preexisting mistrust among partners. (v) "Pragmatic approach to COI and conflict management" conveyed that conflicts were considered manageable components of cross-sector collaboration.

Conclusions: In our study from an early project phase, participants described cross-sector collaboration as valuable and challenges as manageable. They also described potential tensions and mistrust between participants and diverging expectations towards roles and project objectives. These findings suggest that potential obstacles for collaboration were present in the project. This underscores the importance of investing time early in cross-sector research partnerships to clarify roles, align expectations and agree on project goals, which otherwise may turn into obstacles for collaboration between actors with varying mandates, interests, and expectations.

背景:跨部门伙伴关系是一种治理模式,越来越多地用于政策、研究和实践,以应对包括不健康饮食在内的粮食系统挑战。尽管关于它们的价值(尤其是在研究方面)仍在进行辩论,但人们对参与这些伙伴关系的经验了解有限。本研究以挪威为背景,这是一个具有跨部门合作传统的国家。我们研究了挪威跨部门研究伙伴关系NewTools,以探索参与者在项目早期阶段的观点。该伙伴关系由来自研究机构、食品工业、民间社会和政府机构的28个参与者组成,旨在开发两种食品概况模型:一种用于营养,另一种用于环境和社会可持续性。这项研究可以帮助确定影响营养相关跨部门合作进程的初始因素。方法:我们在2022年对17名newtools参与者进行了定性访谈。访谈采用自反性主题分析。结果:确定了五个主题:(i) “参与会议的重要性”说明了与会者对跨部门协作的好处的看法,包括分享专门知识和影响项目成果。(ii)“对合作和项目目标的不同期望”反映了参与者对伙伴参与和项目结果的不同期望。(iii)“对食物分析系统的观点”强调了对两种有待开发的食物分析模型的不同观点,对营养分析模型持更多怀疑态度。“权力不对称和不信任”表明伙伴之间可能存在紧张关系和一些先前存在的不信任。“对COI和冲突管理的务实态度”表示,冲突被认为是跨部门协作的可管理组成部分。结论:在我们早期项目阶段的研究中,参与者认为跨部门协作是有价值的,挑战是可管理的。他们还描述了参与者之间潜在的紧张和不信任,以及对角色和项目目标的不同期望。这些发现表明,合作的潜在障碍存在于项目中。这强调了在跨部门研究伙伴关系中尽早投入时间来澄清角色、调整期望和就项目目标达成一致的重要性,否则这些可能会成为具有不同任务、兴趣和期望的参与者之间合作的障碍。
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引用次数: 0
The association between dietary acid load and Kidney/Liver function in morbidly obese bariatric candidates. 病态肥胖患者膳食酸负荷与肾/肝功能的关系
IF 2.2 Q3 NUTRITION & DIETETICS Pub Date : 2025-12-09 DOI: 10.1186/s40795-025-01216-w
Yasamin Hozhabr Kalali, Ali Nikparast, Fatemeh S Hosseini, Seyed Ali Keshavarz, Hastimansooreh Ansar
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引用次数: 0
Effects of caffeine supplementation on lipid profile and handgrip strength in cirrhotic patients: a randomized, placebo- controlled, clinical trial. 补充咖啡因对肝硬化患者血脂和握力的影响:一项随机、安慰剂对照的临床试验。
IF 2.2 Q3 NUTRITION & DIETETICS Pub Date : 2025-12-04 DOI: 10.1186/s40795-025-01217-9
Seyed Ali Abbas-Hashemi, Zahra Yari, Behzad Hatami, Amir Anushiravani, Shadi Kolahdoozan, Ali Zamanian, Nadia Akbarzadeh, Azita Hekmatdoost
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引用次数: 0
Online and face-to-face education are effective to improve clinical competence regarding nutritional care in early chronic kidney disease. 在线和面授教育能有效提高早期慢性肾病患者营养护理的临床能力。
IF 2.2 Q3 NUTRITION & DIETETICS Pub Date : 2025-12-04 DOI: 10.1186/s40795-025-01206-y
Roxana Michel Márquez-Herrera, Laura Cortés-Sanabria, Alfonso Martin Cueto-Manzano, Héctor Ramón Martínez-Ramírez, Enrique Rojas-Campos, Aaron González-Palacios, Claudia Nelly Orozco-González, Erika Fabiola Gómez-García

Background: Adequate clinical competence (CC) of dietitians for prevention and management of chronic kidney disease (CKD) could have enormous importance to reduce the burden of end- stage kidney disease (ESKD). Unfortunately, this issue has been poorly analyzed, particularly in primary health-care. Online education offers advantages; however, its effect on CC remains unclear. The aim of this study was to compare the effect of an online vs. face-to-face educative intervention on dietitians' clinical competence (CC) regarding nutritional care of early chronic kidney disease (CKD).

Methods: Dietitians were included in an online (N 51) or face-to-face group (N 23) to receive educational interventions developed by a multidisciplinary team, based on the constructivism paradigm and focused on nutritional aspects of prevention and management of early CKD. Content and duration (8 weeks) of both interventions were exactly the same. To evaluate CC, a validated questionnaire (120 points) was applied at the beginning and end of the study. Participation score (80 points) and satisfaction were evaluated.

Results: Age, gender, work experience, and previous training in end-stage kidney disease were similar and > 90% of participants completed the study in both groups. Comparing groups, participation scores were similar (p = 0.75): online 72.2 ± 4.6 points vs. face-to-face 74.1 ± 3.7 points. Baseline CC score was low in both groups: online 51 (41-65) points vs. face-to-face 49 (40-59) points, p = 0.60, but increased at the end of study: online group score increased 63% (26-91%, p < 0.0001) and face-to-face 74% (20-100%, p < 0.0001), without inter-group difference (p = 0.57).

背景:足够的临床能力(CC)的营养师预防和管理慢性肾脏疾病(CKD)可能具有巨大的重要性,以减轻终末期肾脏疾病(ESKD)的负担。不幸的是,对这个问题的分析很差,特别是在初级保健方面。在线教育具有优势;然而,其对CC的影响尚不清楚。本研究的目的是比较在线与面对面教育干预对早期慢性肾脏疾病(CKD)营养护理方面营养师临床能力(CC)的影响。方法:营养师被纳入在线组(N 51)或面对面组(N 23),接受由多学科团队开发的教育干预,基于建构主义范式,重点关注早期CKD预防和管理的营养方面。两种干预措施的内容和持续时间(8周)完全相同。为了评估CC,在研究开始和结束时应用了一份有效的问卷(120分)。评估参与得分(80分)和满意度。结果:年龄、性别、工作经验和以前的终末期肾病培训相似,两组中90%的参与者完成了研究。两组比较,参与得分相似(p = 0.75):在线72.2±4.6分,面对面74.1±3.7分。两组的CC基线得分均较低:在线51(41-65)分,面对面49(40-59)分,p = 0.60,但在研究结束时有所增加:在线组得分增加63% (26-91%,p = 0.60)
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引用次数: 0
Causal effects of Antenatal Care (ANC) on child malnutrition: a machine learning approach in Ethiopia and Rwanda. 产前护理(ANC)对儿童营养不良的因果影响:埃塞俄比亚和卢旺达的机器学习方法。
IF 2.2 Q3 NUTRITION & DIETETICS Pub Date : 2025-11-28 DOI: 10.1186/s40795-025-01208-w
Alehegn Moges Tessema, Temesgen Zewotir, Richard Kabanda
<p><p>Malnutrition among children under five remains a critical public health challenge in Ethiopia and Rwanda, with nearly half of the children in this study population affected by at least one form of undernutrition. This study provides a robust causal analysis of the heterogeneous effects of Antenatal Care (ANC) on child malnutrition, as measured by the Composite Index of Anthropometric Failure (CIAF). Leveraging data from 33,737 mother-child pairs from the Demographic and Health Surveys (DHS) in Ethiopia (N = 22,668) and Rwanda (N = 11,069) across three waves (2005-2015), we employ a machine learning-based Causal Forest model. This approach was chosen specifically to overcome the limitations of traditional regression methods, allowing for the estimation of how the impact of different levels of ANC attendance varies across diverse sociodemographic and health-related subgroups. The results reveal a clear and powerful dose-response relationship. While a single ANC visit has a negligible effect, attending 2-3 visits is associated with a modest 3.5% point reduction in the risk of malnutrition. The strongest impact is seen with the completion of 4 or more visits, which is associated with an average reduction of 5.7% points (ATE: -0.057). Crucially, this average effect masks profound and policy-relevant heterogeneity. The benefits of ANC are massively amplified for the most vulnerable populations; for children in the poorer wealth quintile, 4 + ANC visits are associated with a massive 17.1% point reduction in malnutrition risk-an effect nearly three times the population average. The intervention is also particularly impactful for older mothers (aged 35-49), where it is associated with an 11.9% point risk reduction. Furthermore, the benefits of ANC are amplified by a healthier environment; for children in households with an improved water source, the associated risk reduction is a substantial 7.8% points, demonstrating a powerful synergistic effect between clinical care and public health infrastructure. The application of the Causal Forest model represents a significant advancement, moving beyond a single average effect to uncover this critical heterogeneity and identify for whom, and under what conditions, ANC is most effective. These findings provide robust causal evidence for a necessary shift away from a one-size-fits-all public health strategy. The results strongly advocate for stratified and multi-sectoral interventions. Policy and resources should be intensely focused on ensuring the most vulnerable populations-particularly the poorest households and older mothers-complete the full ANC schedule, as this is where the public health return on investment is highest. Additionally, the synergistic effect with WASH highlights the need to integrate clinical maternal health programs with investments in community-level water and sanitation infrastructure. By tailoring ANC programs and combining them with broader public health improvements, governments c
在埃塞俄比亚和卢旺达,五岁以下儿童营养不良仍然是一项重大的公共卫生挑战,在这项研究的人口中,近一半的儿童至少有一种形式的营养不良。本研究通过人体测量失败综合指数(CIAF)对产前护理(ANC)对儿童营养不良的异质性影响进行了强有力的因果分析。利用来自埃塞俄比亚(N = 22,668)和卢旺达(N = 11069)三波(2005-2015)人口与健康调查(DHS)的33,737对母子的数据,我们采用了基于机器学习的因果森林模型。选择这种方法是专门为了克服传统回归方法的局限性,允许估计不同水平的ANC出席率在不同社会人口统计学和健康相关亚组中的影响。结果显示了一个明确而有力的剂量-反应关系。虽然一次ANC访问的影响可以忽略不计,但参加2-3次访问与营养不良风险降低3.5%有关。最强烈的影响是完成4次或更多的访问,这与平均减少5.7%分(ATE: -0.057)有关。至关重要的是,这种平均效应掩盖了与政策相关的深刻异质性。对于最脆弱的人群,非洲人国民大会的好处被大大放大;对于较贫穷的五分之一的儿童来说,4次以上的ANC访问与营养不良风险大幅降低17.1%相关,这一效果几乎是人口平均水平的三倍。该干预措施对年龄较大的母亲(35-49岁)也特别有效,与11.9%的风险降低有关。此外,更健康的环境扩大了非裔美国人的利益;对于水源改善的家庭中的儿童,相关的风险降低了7.8%,这表明临床护理和公共卫生基础设施之间具有强大的协同效应。因果森林模型的应用代表了一个重大的进步,超越了单一的平均效应,揭示了这种关键的异质性,并确定了对谁,在什么条件下,ANC是最有效的。这些发现为放弃一刀切的公共卫生战略提供了强有力的因果证据。研究结果强烈提倡分层和多部门干预。政策和资源应高度集中于确保最脆弱的人口——特别是最贫穷的家庭和老年母亲——完成非洲人国民大会的全部计划,因为这是公共卫生投资回报最高的地方。此外,与讲卫生运动的协同效应凸显了将临床孕产妇保健方案与社区一级水和卫生基础设施投资结合起来的必要性。通过调整儿童营养不良计划,并将其与更广泛的公共卫生改善相结合,政府可以制定更全面、更有效的战略,加快在埃塞俄比亚、卢旺达和类似高负担国家消除儿童营养不良的进程。
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引用次数: 0
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BMC Nutrition
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