首页 > 最新文献

International Journal of Population Data Science最新文献

英文 中文
The impact of COVID-19 pandemic on trends in the recorded incidence of Long-Term Conditions identified from routine electronic health records between 2000 and 2021 in Wales: a population data linkage study. 2019冠状病毒病大流行对2000年至2021年威尔士常规电子健康记录中确定的长期疾病记录发病率趋势的影响:一项人口数据联系研究。
Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2022-08-25 DOI: 10.23889/ijpds.v7i3.2011
Cathy Qi, T. Osborne, R. Bailey, J. Hollinghurst, A. Akbari, A. Cooper, Ruth Crowder, H. Peters, R. Law, Anthony Davies, R. Lewis, Mark C Walker, Adrian Edwards, R. Lyons
BackgroundThe COVID-19 pandemic has resulted in delayed diagnosis and treatment for cancer patients and increases in elective surgery waiting lists. The impact on other ‘long-term’ conditions (LTCs) is unclear. We examined the effects of the pandemic on the recorded incidence of 20 LTCs to inform decisions on treatment pathways and resource allocation. ApproachWe included Welsh residents diagnosed with any of 20 LTCs for the first time between 2000-2021. Data were accessed and analysed within the Secure Anonymised Information Linkage (SAIL) Databank. The primary aim was to assess the impact of the COVID-19 pandemic on trends in recorded incidence. Secondarily we examined incidence by socio-demographic and clinical subgroups: age, sex, deprivation quintile, ethnicity, frailty score and learning disability. Incidence were presented as monthly rates for each LTC. We performed interrupted time series analyses to estimate; the immediate and long-term change in rates following the pandemic; and the size of the undiagnosed population. ResultsWe included 2,206,070 individuals diagnosed with at least one LTC. An immediate reduction in recording of new diagnoses was observed in April 2020 across all 20 LTCs, followed by a gradual recovery towards pre-pandemic levels over the next 18 months, though at different rates across conditions. The largest difference between observed and expected (as predicted using pre-pandemic trends) incidence between January 2020 and June 2021 were in the diagnoses of COPD (-43%, 95% CI (-50%, -34%)), Asthma, Hypertension and Depression and the smallest difference was in Type 1 diabetes, dementia, stroke and TIA (-8%, 95% CI (-19% ,5%)). Differences in the proportions of incidence by socio-demographic and clinical subgroups in the years preceding and following the pandemic have also been analysed (results to be finalised). ConclusionThere was an abrupt reduction in the observed incidence of all 20 LTCs after March 2020 followed by a gradual recovery over consequent months towards pre-pandemic levels. Of 20 LTCs, 15 strongly indicate a reservoir of yet undiagnosed patients. The results from this study will have implications in resource allocation.
新冠肺炎疫情导致癌症患者的诊断和治疗延迟,择期手术等待名单增加。对其他“长期”状况(ltc)的影响尚不清楚。我们研究了大流行对20例LTCs记录发病率的影响,为治疗途径和资源分配决策提供信息。我们纳入了2000年至2021年间首次被诊断患有20种LTCs中的任何一种的威尔士居民。数据在安全匿名信息链接(SAIL)数据库中被访问和分析。主要目的是评估COVID-19大流行对记录发病率趋势的影响。其次,我们检查了社会人口统计学和临床亚组的发病率:年龄、性别、剥夺五分之一、种族、虚弱评分和学习障碍。发病率以每个LTC的月发病率表示。我们进行了中断时间序列分析来估计;大流行后发病率的近期和长期变化;以及未确诊人群的规模。结果:我们纳入了2,206,070名被诊断为至少一种LTC的个体。2020年4月,所有20个长期诊断中心的新诊断记录立即减少,随后在接下来的18个月里逐渐恢复到大流行前的水平,尽管不同条件下的恢复速度不同。2020年1月至2021年6月期间观察到的发病率与预期发病率(根据大流行前趋势预测)之间的最大差异是慢性阻塞性肺病(-43%,95%可信区间(-50%,-34%))、哮喘、高血压和抑郁症的诊断,差异最小的是1型糖尿病、痴呆、中风和TIA(-8%, 95%可信区间(-19%,5%))。还分析了在大流行前后几年中社会人口和临床亚组发病率的差异(结果有待最后确定)。结论:2020年3月之后,所有20例LTCs的观察发病率突然下降,随后几个月逐渐恢复到大流行前的水平。在20个LTCs中,有15个强烈表明存在尚未确诊的患者。这项研究的结果将对资源分配产生影响。
{"title":"The impact of COVID-19 pandemic on trends in the recorded incidence of Long-Term Conditions identified from routine electronic health records between 2000 and 2021 in Wales: a population data linkage study.","authors":"Cathy Qi, T. Osborne, R. Bailey, J. Hollinghurst, A. Akbari, A. Cooper, Ruth Crowder, H. Peters, R. Law, Anthony Davies, R. Lewis, Mark C Walker, Adrian Edwards, R. Lyons","doi":"10.23889/ijpds.v7i3.2011","DOIUrl":"https://doi.org/10.23889/ijpds.v7i3.2011","url":null,"abstract":"BackgroundThe COVID-19 pandemic has resulted in delayed diagnosis and treatment for cancer patients and increases in elective surgery waiting lists. The impact on other ‘long-term’ conditions (LTCs) is unclear. We examined the effects of the pandemic on the recorded incidence of 20 LTCs to inform decisions on treatment pathways and resource allocation. \u0000ApproachWe included Welsh residents diagnosed with any of 20 LTCs for the first time between 2000-2021. \u0000Data were accessed and analysed within the Secure Anonymised Information Linkage (SAIL) Databank. \u0000The primary aim was to assess the impact of the COVID-19 pandemic on trends in recorded incidence. Secondarily we examined incidence by socio-demographic and clinical subgroups: age, sex, deprivation quintile, ethnicity, frailty score and learning disability. \u0000Incidence were presented as monthly rates for each LTC. We performed interrupted time series analyses to estimate; the immediate and long-term change in rates following the pandemic; and the size of the undiagnosed population. \u0000ResultsWe included 2,206,070 individuals diagnosed with at least one LTC. \u0000An immediate reduction in recording of new diagnoses was observed in April 2020 across all 20 LTCs, followed by a gradual recovery towards pre-pandemic levels over the next 18 months, though at different rates across conditions. The largest difference between observed and expected (as predicted using pre-pandemic trends) incidence between January 2020 and June 2021 were in the diagnoses of COPD (-43%, 95% CI (-50%, -34%)), Asthma, Hypertension and Depression and the smallest difference was in Type 1 diabetes, dementia, stroke and TIA (-8%, 95% CI (-19% ,5%)). \u0000Differences in the proportions of incidence by socio-demographic and clinical subgroups in the years preceding and following the pandemic have also been analysed (results to be finalised). \u0000ConclusionThere was an abrupt reduction in the observed incidence of all 20 LTCs after March 2020 followed by a gradual recovery over consequent months towards pre-pandemic levels. Of 20 LTCs, 15 strongly indicate a reservoir of yet undiagnosed patients. The results from this study will have implications in resource allocation.","PeriodicalId":36483,"journal":{"name":"International Journal of Population Data Science","volume":"1977 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41262938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anti-asthmatic prescriptions in children with and without congenital anomalies: a European data linkage study. 先天性和非先天性畸形儿童的平喘处方:一项欧洲数据关联研究。
Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2022-08-25 DOI: 10.23889/ijpds.v7i3.1889
Natalie Divin, E. Garne, J. Morris, M. Loane
ObjectivesAsthma is the most common chronic disease in childhood, yet little is known about rates of asthma and wheezing in children with congenital anomalies. This study explored the prevalence and risk of receiving anti-asthmatic prescriptions in children with congenital anomalies compared to children without anomalies in six European regions/countries.ApproachThis was a EUROlinkCAT population-based linkage cohort study involving children from 0-9 years of age born between 2000-2014. Congenital anomaly data from six EUROCAT registries were linked to births data in national/vital statistics and to electronic prescription databases. Prescription/pharmacy dispensing records across regions were standardised to a Common Data Model. Anatomical Therapeutic Chemical classification codes beginning with R03 were used to identify anti-asthmatic prescriptions. Random-effects meta-analyses were performed to identify both the relative risk (RR) of receiving >1 anti-asthmatic prescription in a year relative to the reference group, and the heterogeneity of prevalence rates across registries and age group.ResultsA total of 5.1% of children with congenital anomalies and 4.9% of reference children were dropped from the study as they were not linked. Children with congenital anomalies (n=60,662) had a higher prevalence of >1 anti-asthmatic prescription and a significantly higher risk of being prescribed anti-asthmatics (RR=1.41, 95% CI 1.35-1.48) compared to reference children (n=1,722,912). The increased risk was consistent across all age groups. Children with congenital anomalies were more likely to be prescribed beta-2 agonists (RR=1.71, 95% CI 1.60-1.83) and inhaled corticosteroids (RR=1.74, 95% CI 1.61-1.87). Children with oesophageal atresia, diaphragmatic hernia, genetic syndromes and chromosomal anomalies had over twice the risk of being prescribed anti-asthmatics compared to reference children. Regional differences in prevalence and risk of anti-asthmatic prescriptions were identified.ConclusionChildren aged <10 years with congenital anomalies consistently had higher prevalence and risk of receiving >1 anti-asthmatic prescription across age group and across European regions. This study demonstrates that information on the prevalence of anti-asthmatic prescriptions issued/dispensed can be obtained through data linkage to monitor changes in prevalence over time.
目的哮喘是儿童最常见的慢性疾病,但对先天性异常儿童哮喘和喘息的发病率知之甚少。本研究探讨了6个欧洲地区/国家先天性异常儿童与非异常儿童接受抗哮喘处方的患病率和风险。这是一项基于EUROlinkCAT人群的连锁队列研究,涉及2000-2014年间出生的0-9岁儿童。来自六个EUROCAT登记处的先天性异常数据与国家/生命统计中的出生数据和电子处方数据库相关联。各地区的处方/药房配药记录被标准化为通用数据模型。以R03开头的解剖治疗化学分类代码用于识别抗哮喘处方。进行随机效应荟萃分析,以确定一年内相对于参照组接受bbb1抗哮喘处方的相对风险(RR),以及不同登记中心和年龄组患病率的异质性。结果5.1%的先天性异常患儿和4.9%的对照患儿因未关联而被排除在研究之外。与对照儿童(n=1,722,912)相比,先天性异常儿童(n=60,662)使用bbb1类抗哮喘药物的比例更高,服用抗哮喘药物的风险也明显更高(RR=1.41, 95% CI 1.35-1.48)。风险的增加在所有年龄组中都是一致的。有先天性异常的儿童更可能使用β -2激动剂(RR=1.71, 95% CI 1.60-1.83)和吸入皮质类固醇(RR=1.74, 95% CI 1.61-1.87)。与对照儿童相比,患有食管闭锁、膈疝、遗传综合征和染色体异常的儿童服用抗哮喘药物的风险超过两倍。确定了抗哮喘处方患病率和风险的地区差异。结论1岁儿童抗哮喘处方具有跨年龄组和跨欧洲地区的特点。本研究表明,可以通过数据链接获得有关已开/配发的抗哮喘处方的患病率信息,以监测患病率随时间的变化。
{"title":"Anti-asthmatic prescriptions in children with and without congenital anomalies: a European data linkage study.","authors":"Natalie Divin, E. Garne, J. Morris, M. Loane","doi":"10.23889/ijpds.v7i3.1889","DOIUrl":"https://doi.org/10.23889/ijpds.v7i3.1889","url":null,"abstract":"ObjectivesAsthma is the most common chronic disease in childhood, yet little is known about rates of asthma and wheezing in children with congenital anomalies. This study explored the prevalence and risk of receiving anti-asthmatic prescriptions in children with congenital anomalies compared to children without anomalies in six European regions/countries.\u0000ApproachThis was a EUROlinkCAT population-based linkage cohort study involving children from 0-9 years of age born between 2000-2014. Congenital anomaly data from six EUROCAT registries were linked to births data in national/vital statistics and to electronic prescription databases. Prescription/pharmacy dispensing records across regions were standardised to a Common Data Model. Anatomical Therapeutic Chemical classification codes beginning with R03 were used to identify anti-asthmatic prescriptions. Random-effects meta-analyses were performed to identify both the relative risk (RR) of receiving >1 anti-asthmatic prescription in a year relative to the reference group, and the heterogeneity of prevalence rates across registries and age group.\u0000ResultsA total of 5.1% of children with congenital anomalies and 4.9% of reference children were dropped from the study as they were not linked. Children with congenital anomalies (n=60,662) had a higher prevalence of >1 anti-asthmatic prescription and a significantly higher risk of being prescribed anti-asthmatics (RR=1.41, 95% CI 1.35-1.48) compared to reference children (n=1,722,912). The increased risk was consistent across all age groups. Children with congenital anomalies were more likely to be prescribed beta-2 agonists (RR=1.71, 95% CI 1.60-1.83) and inhaled corticosteroids (RR=1.74, 95% CI 1.61-1.87). Children with oesophageal atresia, diaphragmatic hernia, genetic syndromes and chromosomal anomalies had over twice the risk of being prescribed anti-asthmatics compared to reference children. Regional differences in prevalence and risk of anti-asthmatic prescriptions were identified.\u0000ConclusionChildren aged <10 years with congenital anomalies consistently had higher prevalence and risk of receiving >1 anti-asthmatic prescription across age group and across European regions. This study demonstrates that information on the prevalence of anti-asthmatic prescriptions issued/dispensed can be obtained through data linkage to monitor changes in prevalence over time.","PeriodicalId":36483,"journal":{"name":"International Journal of Population Data Science","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44544631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Feasibility of evaluating COVID-19 vaccine effectiveness and variant severity through a routine health information exchange. 通过常规健康信息交流评估新冠肺炎疫苗有效性和变异严重性的可行性。
Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2022-08-25 DOI: 10.23889/ijpds.v7i3.2066
A. Boulle, A. Heekes, H. Hussey, Reshna Kassanjee, M. Davies
ObjectivesTo date South Africa has experienced four distinct COVID-19 waves due to ancestral, Beta, Delta and Omnicron SARS-CoV-2 variants. We sought to answer pertinent public health questions in a timely manner as new COVID-19 variants emerge(d) using routine health service data linked through a service-facing health information exchange (HIE). ApproachA population cohort was defined amongst regular health service users in the Western Cape Province of South Africa based on recent utilisation of public sector services as reflected in the Provincial Health Data Centre (PHDC) which functions as a HIE.  Infection, hospitalisation and mortality data were derived from routinely linked laboratory, service and national vital registration data sources.  Serology done on residual specimens of patients monitored for HIV and diabetes treatment progress were linked to the PHDC, as were vaccination data from the national vaccination information system.  A single linked and de-identified dataset was exported for analysis purposes. ResultsBased on accessing services in the preceding 3 years, a cohort of 3.5 million adult patients could be enumerated and linked to co-morbidity and SARS-CoV-2 outcome data. Serology from 16,000 specimens spread across the three inter-wave periods, and vaccine data from amongst the 5 million vaccine doses given in the Province, could also be linked.  Variants could be identified by wave or by PCR assay target anomalies during cross-over periods. Publishable variant severity analyses were feasible from the sub-cohort of patients with diagnosed COVID-19, and variant-specific vaccine effectiveness was assessible amongst cases, in the population cohort, and in patients with HIV.  The impact of prior infection and marginal value of vaccination in those with prior infection was assessible within the serology sub-cohort. ConclusionA single linked de-identified dataset derived from an operational HIE was able to quickly address critical public health questions related to COVID-19 variants in a privacy-preserving manner.
目的迄今为止,由于祖先、贝塔、德尔塔和奥密克戎SARS-CoV-2变种,南非经历了四次不同的新冠肺炎疫情。随着新冠肺炎新变种的出现,我们寻求及时回答相关的公共卫生问题(d)使用通过面向服务的健康信息交换(HIE)链接的常规健康服务数据。方法根据作为HIE的省卫生数据中心(PHDC)最近对公共部门服务的使用情况,在南非西开普省的常规卫生服务用户中定义了人口群体。感染、住院和死亡率数据来自常规关联的实验室、服务和国家生命登记数据来源。对监测艾滋病毒和糖尿病治疗进展的患者残余样本进行的血清学检查与PHDC有关,国家疫苗接种信息系统的疫苗接种数据也是如此。为了进行分析,导出了一个单独的链接和取消标识的数据集。结果根据前3年获得的服务,可以列举350万成年患者的队列,并将其与合并发病率和严重急性呼吸系统综合征冠状病毒2型的结果数据联系起来。来自16000个样本的血清学分布在三个波间期,以及来自该省500万剂疫苗的疫苗数据也可能存在关联。变异可以通过波或通过交叉期内的PCR检测目标异常来识别。从诊断为新冠肺炎的患者的亚队列中进行可发表的变异严重性分析是可行的,并且可在病例、人群队列和艾滋病毒患者中评估变异特异性疫苗的有效性。既往感染的影响和疫苗接种对既往感染者的边际价值可在血清学亚队列中评估。结论来自操作性HIE的单一链接去识别数据集能够以保密的方式快速解决与新冠肺炎变异相关的关键公共卫生问题。
{"title":"Feasibility of evaluating COVID-19 vaccine effectiveness and variant severity through a routine health information exchange.","authors":"A. Boulle, A. Heekes, H. Hussey, Reshna Kassanjee, M. Davies","doi":"10.23889/ijpds.v7i3.2066","DOIUrl":"https://doi.org/10.23889/ijpds.v7i3.2066","url":null,"abstract":"ObjectivesTo date South Africa has experienced four distinct COVID-19 waves due to ancestral, Beta, Delta and Omnicron SARS-CoV-2 variants. We sought to answer pertinent public health questions in a timely manner as new COVID-19 variants emerge(d) using routine health service data linked through a service-facing health information exchange (HIE). \u0000ApproachA population cohort was defined amongst regular health service users in the Western Cape Province of South Africa based on recent utilisation of public sector services as reflected in the Provincial Health Data Centre (PHDC) which functions as a HIE.  Infection, hospitalisation and mortality data were derived from routinely linked laboratory, service and national vital registration data sources.  Serology done on residual specimens of patients monitored for HIV and diabetes treatment progress were linked to the PHDC, as were vaccination data from the national vaccination information system.  A single linked and de-identified dataset was exported for analysis purposes. \u0000ResultsBased on accessing services in the preceding 3 years, a cohort of 3.5 million adult patients could be enumerated and linked to co-morbidity and SARS-CoV-2 outcome data. Serology from 16,000 specimens spread across the three inter-wave periods, and vaccine data from amongst the 5 million vaccine doses given in the Province, could also be linked.  Variants could be identified by wave or by PCR assay target anomalies during cross-over periods. Publishable variant severity analyses were feasible from the sub-cohort of patients with diagnosed COVID-19, and variant-specific vaccine effectiveness was assessible amongst cases, in the population cohort, and in patients with HIV.  The impact of prior infection and marginal value of vaccination in those with prior infection was assessible within the serology sub-cohort. \u0000ConclusionA single linked de-identified dataset derived from an operational HIE was able to quickly address critical public health questions related to COVID-19 variants in a privacy-preserving manner.","PeriodicalId":36483,"journal":{"name":"International Journal of Population Data Science","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42492628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Policy Impact Case Study Using Real World Data from Welsh Government Fuel Poverty Schemes to Inform Scheme Design. 使用威尔士政府燃料贫困计划的真实世界数据进行政策影响案例研究,以告知计划设计。
Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2022-08-25 DOI: 10.23889/ijpds.v7i3.1894
Sarah E. Lowe, S. Morrison-Rees
ObjectivesTo reduce fuel poverty in Wales: the Welsh Government developed schemes to provide energy efficiency improvements to lower income households. To inform scheme design: investigate health impacts by linking scheme data to health records. Presented objective: to demonstrate how research findings using real world data can impact policy focus. ApproachThe research was conducted by an independent researcher at Swansea University who co-produced research questions with the Welsh Government Fuel Poverty Policy Team. A longitudinal dataset was created by linking anonymised ‘Warm Homes: Nest’ improvements data to residents’ routine health records in the SAIL Databank at Swansea University. We examined recipient health before and after intervention compared with controls. A high-level policy briefing and research report were published in the Welsh Government Social Research – Analysis for Policy series. Findings were used to design and pilot new eligibility criteria to capture low-income individuals with a respiratory, circulatory or mental health condition. ResultsThis presentation will describe the policy impact pathway from initial discussions with policymakers to real world change, including: securing ESRC funding for a Knowledge Transfer Fellowship, which included a 2013 data linking demonstration project… …which allowed funding to be secured for a 2015-18 research project focused on the impact of improvements on recipient health… …which published emerging findings in 2016… …and substantive findings in 2017, showing a significant positive impact of improvements on recipient health… …which policymakers used to design a pilot to test ways to widen eligibility criteria to include individuals on a low income with a respiratory, circulatory or mental health condition… …which led to scheme criteria being widened in 2019. By 2021, 25% of recipients entered the scheme via the ‘health route’. ConclusionBy delivering research findings generated using linked real world data, and focused on questions co-produced with policymakers, researchers can successfully impact the design and implementation of government policy, thereby improving the lives of people in the real world - in this case, the health of the citizens of Wales.
目标:减少威尔士的燃料贫困:威尔士政府制定了提高低收入家庭能源效率的计划。为方案设计提供信息:通过将方案数据与健康记录联系起来,调查健康影响。提出的目标:展示使用真实世界数据的研究结果如何影响政策重点。这项研究是由斯旺西大学的一名独立研究员进行的,他与威尔士政府燃料贫困政策小组共同提出了研究问题。通过将匿名的“温暖之家:巢”改善数据与斯旺西大学SAIL数据库中居民的日常健康记录联系起来,创建了一个纵向数据集。与对照组相比,我们在干预前后检查了接受者的健康状况。《威尔士政府社会研究-政策分析》系列发表了一份高级别政策简报和研究报告。研究结果被用于设计和试点新的资格标准,以捕获有呼吸、循环或精神健康状况的低收入个体。本演讲将描述从与政策制定者的初步讨论到现实世界变化的政策影响途径,包括:确保ESRC为知识转移研究金提供资金,其中包括2013年的数据链接示范项目... ...,该项目为2015-18年的研究项目提供资金,重点关注改善对接受者健康的影响... ...,该项目于2016年发表了新发现... ...,并于2017年发表了实质性发现;显示对接受者健康的改善产生了重大的积极影响... ...政策制定者用来设计一个试点,以测试扩大资格标准的方法,以包括患有呼吸、循环或精神健康状况的低收入个人... ...,这导致计划标准在2019年扩大。到2021年,25%的受助人通过"健康途径"加入该计划。通过提供使用关联的真实世界数据产生的研究结果,并将重点放在与政策制定者共同产生的问题上,研究人员可以成功地影响政府政策的设计和实施,从而改善现实世界中人们的生活——在这种情况下,改善威尔士公民的健康。
{"title":"A Policy Impact Case Study Using Real World Data from Welsh Government Fuel Poverty Schemes to Inform Scheme Design.","authors":"Sarah E. Lowe, S. Morrison-Rees","doi":"10.23889/ijpds.v7i3.1894","DOIUrl":"https://doi.org/10.23889/ijpds.v7i3.1894","url":null,"abstract":"ObjectivesTo reduce fuel poverty in Wales: the Welsh Government developed schemes to provide energy efficiency improvements to lower income households. \u0000To inform scheme design: investigate health impacts by linking scheme data to health records. \u0000Presented objective: to demonstrate how research findings using real world data can impact policy focus. \u0000ApproachThe research was conducted by an independent researcher at Swansea University who co-produced research questions with the Welsh Government Fuel Poverty Policy Team. \u0000A longitudinal dataset was created by linking anonymised ‘Warm Homes: Nest’ improvements data to residents’ routine health records in the SAIL Databank at Swansea University. We examined recipient health before and after intervention compared with controls. \u0000A high-level policy briefing and research report were published in the Welsh Government Social Research – Analysis for Policy series. \u0000Findings were used to design and pilot new eligibility criteria to capture low-income individuals with a respiratory, circulatory or mental health condition. \u0000ResultsThis presentation will describe the policy impact pathway from initial discussions with policymakers to real world change, including: \u0000 \u0000securing ESRC funding for a Knowledge Transfer Fellowship, which included a 2013 data linking demonstration project… \u0000…which allowed funding to be secured for a 2015-18 research project focused on the impact of improvements on recipient health… \u0000…which published emerging findings in 2016… \u0000…and substantive findings in 2017, showing a significant positive impact of improvements on recipient health… \u0000…which policymakers used to design a pilot to test ways to widen eligibility criteria to include individuals on a low income with a respiratory, circulatory or mental health condition… \u0000…which led to scheme criteria being widened in 2019. \u0000 \u0000By 2021, 25% of recipients entered the scheme via the ‘health route’. \u0000ConclusionBy delivering research findings generated using linked real world data, and focused on questions co-produced with policymakers, researchers can successfully impact the design and implementation of government policy, thereby improving the lives of people in the real world - in this case, the health of the citizens of Wales.","PeriodicalId":36483,"journal":{"name":"International Journal of Population Data Science","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46075573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysing Siamese Neural Network Architectures for Computing Name Similarity. 分析用于计算名称相似性的暹罗神经网络架构。
Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2022-08-25 DOI: 10.23889/ijpds.v7i3.2077
Nicholas Vinden, Jérémy Foxcroft, L. Antonie
IntroductionA wide assortment of string similarity measures can be used to determine how similar two names are. A diverse set of discriminating and independent features for name similarity are important for classification during record linkage. A Siamese neural network could surpass traditional string similarity measures for the name similarity problem. Objectives and ApproachThis research aims to compare a classifier based on the Siamese network architecture with a Random Forest classifier. In addition to comparing overall performance, we seek to answer whether there are any special properties of certain matching name pairs where the complexity of the Siamese network offers particular benefit. Our data consists of 25,000 last name pairings, with each pair being two variants of a family name. Name similarity predictions from the Siamese network are compared to a Random Forest model that serves as an ensemble of existing string similarity measures. ResultsWe compare the similarity scores yielded by the two methods and discuss the results. We describe the representation of names to each method; name representation is computed formulaically for the traditional measures but is learned by the Siamese network during training. The comparison of different methods is made both in terms of their similarity prediction quality, and the computational cost to generate the predictions. As expected, the Siamese network necessitates a significant computational cost to train. Unexpectedly, the ensemble of traditional measures yields almost identical overall classification performance. However, we expect that further analysis of false positives and false negatives will yield some insight into when practitioners should consider one method over the other. Conclusions/ImplicationsResults suggest that there may be instances where a Siamese network outperforms other similarity measures, although training a Siamese network comes at a considerable computational cost. It is worth considering this approach to name similarity as an additional similarity feature when performing record linkage tasks.
引言可以使用各种各样的字符串相似性度量来确定两个名称的相似程度。在记录链接过程中,名称相似性的一组不同的判别和独立特征对于分类很重要。在名称相似性问题上,暹罗神经网络可以超越传统的字符串相似性度量。目的和方法本研究旨在将基于暹罗网络架构的分类器与随机森林分类器进行比较。除了比较整体性能外,我们还试图回答某些匹配名称对是否有任何特殊性质,其中暹罗网络的复杂性提供了特别的好处。我们的数据由25000个姓氏配对组成,每个配对都是一个姓氏的两个变体。将暹罗网络的名称相似性预测与随机森林模型进行比较,该模型用作现有字符串相似性度量的集合。结果我们比较了两种方法得出的相似性得分,并对结果进行了讨论。我们描述了每个方法的名称表示;名称表示是为传统度量公式化计算的,但在训练过程中由暹罗网络学习。对不同方法的相似性预测质量和生成预测的计算成本进行了比较。正如预期的那样,暹罗网络需要大量的计算成本来进行训练。出乎意料的是,传统度量的集合产生了几乎相同的总体分类性能。然而,我们预计,对假阳性和假阴性的进一步分析将对从业者何时应该考虑一种方法而不是另一种方法产生一些见解。结论/含义结果表明,尽管训练暹罗网络需要相当大的计算成本,但暹罗网络可能在某些情况下优于其他相似性度量。在执行记录链接任务时,值得考虑将这种名称相似性方法作为额外的相似性特征。
{"title":"Analysing Siamese Neural Network Architectures for Computing Name Similarity.","authors":"Nicholas Vinden, Jérémy Foxcroft, L. Antonie","doi":"10.23889/ijpds.v7i3.2077","DOIUrl":"https://doi.org/10.23889/ijpds.v7i3.2077","url":null,"abstract":"IntroductionA wide assortment of string similarity measures can be used to determine how similar two names are. A diverse set of discriminating and independent features for name similarity are important for classification during record linkage. A Siamese neural network could surpass traditional string similarity measures for the name similarity problem. \u0000Objectives and ApproachThis research aims to compare a classifier based on the Siamese network architecture with a Random Forest classifier. In addition to comparing overall performance, we seek to answer whether there are any special properties of certain matching name pairs where the complexity of the Siamese network offers particular benefit. \u0000Our data consists of 25,000 last name pairings, with each pair being two variants of a family name. Name similarity predictions from the Siamese network are compared to a Random Forest model that serves as an ensemble of existing string similarity measures. \u0000ResultsWe compare the similarity scores yielded by the two methods and discuss the results. We describe the representation of names to each method; name representation is computed formulaically for the traditional measures but is learned by the Siamese network during training. The comparison of different methods is made both in terms of their similarity prediction quality, and the computational cost to generate the predictions. \u0000As expected, the Siamese network necessitates a significant computational cost to train. Unexpectedly, the ensemble of traditional measures yields almost identical overall classification performance. However, we expect that further analysis of false positives and false negatives will yield some insight into when practitioners should consider one method over the other. \u0000Conclusions/ImplicationsResults suggest that there may be instances where a Siamese network outperforms other similarity measures, although training a Siamese network comes at a considerable computational cost. It is worth considering this approach to name similarity as an additional similarity feature when performing record linkage tasks.","PeriodicalId":36483,"journal":{"name":"International Journal of Population Data Science","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46138847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Care trajectory in homes care users across mortality-risk profiles: an observational study. 家庭护理轨迹-护理使用者的死亡风险概况:一项观察性研究。
Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2022-08-25 DOI: 10.23889/ijpds.v7i3.1847
Maya Murmann, D. Manuel, P. Tanuseputro, C. Bennett, M. Pugliese, Rhiannon Roberts, Wenshan Li, A. Hsu
ObjectivesRESPECT is a prognostic tool, developed using linked population-based data, to predict 6-month mortality in community-dwelling older adults. RESPECT is implemented and openly accessible as a web-based tool on ProjectBigLife.ca, where over 700,000 calculations have been performed to date. Our objective was to describe healthcare utilization patterns among home care (HC) users across mortality risk profiles generated from RESPECT to inform care planning for older persons who have varying mortality risks and levels of care needs as they decline. ApproachWe conducted a retrospective cohort study examining healthcare use among HC users in Ontario, Canada, who received at least one interRAI HC assessment between April 2018 and September 2019.  Using linked health administrative data at the individual level, we examined the use of acute care (hospitalizations and emergency department (ED) visits), long-term care (LTC), and palliative home care within 6-months of each assessment and prognostication using RESPECT. Mortality risk profiles from RESPECT were created based on the median survival. ResultsThe cohort comprised 247,377 community-dwelling older adults; 14.3% died within 6-months of an assessment. Among decedents, half (51.51%) of HC users with a predicted median survival of less than 3-months received at least one palliative care home visit; 39.17%, 34.82% and 13.84% visited the ED, were hospitalized, or were admitted to LTC, respectively. The proportion of assessments that received at least one palliative HC visit declined to 43.11% and 30.28% of assessments with a median survival between 3- and 6-months and those between 6-months and 12-months, respectively.  The proportion of assessments with an acute care use increases with increasing median survival. ConclusionA considerable proportion of people at the end-of-life do not receive any palliative home care and continued to be institutionalized. This may be indication that the reduced life expectancies and palliative care needs of many older adults are not being recognized, thus demonstrating the value of prognostic models like RESPECT to inform care planning  for individuals in their final years of life.
respect是一种预后工具,使用相关的基于人群的数据开发,用于预测社区居住的老年人6个月死亡率。RESPECT作为基于web的工具在ProjectBigLife上实现并公开访问。Ca,迄今为止已经进行了70多万次计算。我们的目的是通过RESPECT生成的死亡率风险概况来描述家庭护理(HC)使用者的医疗保健利用模式,为老年人的护理规划提供信息,这些老年人随着年龄的下降有不同的死亡率风险和护理需求水平。方法:我们进行了一项回顾性队列研究,调查了加拿大安大略省HC使用者的医疗保健使用情况,这些使用者在2018年4月至2019年9月期间至少接受了一次rai HC评估。使用个人层面的相关健康管理数据,我们检查了每次评估和使用RESPECT进行预测后6个月内的急性护理(住院和急诊就诊)、长期护理(LTC)和姑息性家庭护理的使用情况。RESPECT的死亡风险概况是基于中位生存期创建的。结果该队列包括247,377名社区居住老年人;14.3%在评估后6个月内死亡。在死者中,半数(51.51%)预期中位生存期小于3个月的HC使用者至少接受过一次姑息治疗家访;分别有39.17%、34.82%和13.84%的患者去急诊科就诊、住院或住院。接受至少一次姑息性HC访问的评估比例分别下降至43.11%和30.28%,中位生存期分别为3至6个月和6至12个月。急性护理使用的评估比例随着中位生存期的增加而增加。结论相当比例的临终患者没有接受任何姑息性家庭护理,而是继续被机构化。这可能表明,许多老年人的预期寿命缩短和姑息治疗需求没有得到认识,从而证明了像RESPECT这样的预后模型的价值,可以为个人生命最后几年的护理计划提供信息。
{"title":"Care trajectory in homes care users across mortality-risk profiles: an observational study.","authors":"Maya Murmann, D. Manuel, P. Tanuseputro, C. Bennett, M. Pugliese, Rhiannon Roberts, Wenshan Li, A. Hsu","doi":"10.23889/ijpds.v7i3.1847","DOIUrl":"https://doi.org/10.23889/ijpds.v7i3.1847","url":null,"abstract":"ObjectivesRESPECT is a prognostic tool, developed using linked population-based data, to predict 6-month mortality in community-dwelling older adults. RESPECT is implemented and openly accessible as a web-based tool on ProjectBigLife.ca, where over 700,000 calculations have been performed to date. Our objective was to describe healthcare utilization patterns among home care (HC) users across mortality risk profiles generated from RESPECT to inform care planning for older persons who have varying mortality risks and levels of care needs as they decline. \u0000ApproachWe conducted a retrospective cohort study examining healthcare use among HC users in Ontario, Canada, who received at least one interRAI HC assessment between April 2018 and September 2019.  Using linked health administrative data at the individual level, we examined the use of acute care (hospitalizations and emergency department (ED) visits), long-term care (LTC), and palliative home care within 6-months of each assessment and prognostication using RESPECT. Mortality risk profiles from RESPECT were created based on the median survival. \u0000ResultsThe cohort comprised 247,377 community-dwelling older adults; 14.3% died within 6-months of an assessment. Among decedents, half (51.51%) of HC users with a predicted median survival of less than 3-months received at least one palliative care home visit; 39.17%, 34.82% and 13.84% visited the ED, were hospitalized, or were admitted to LTC, respectively. The proportion of assessments that received at least one palliative HC visit declined to 43.11% and 30.28% of assessments with a median survival between 3- and 6-months and those between 6-months and 12-months, respectively.  The proportion of assessments with an acute care use increases with increasing median survival. \u0000ConclusionA considerable proportion of people at the end-of-life do not receive any palliative home care and continued to be institutionalized. This may be indication that the reduced life expectancies and palliative care needs of many older adults are not being recognized, thus demonstrating the value of prognostic models like RESPECT to inform care planning  for individuals in their final years of life.","PeriodicalId":36483,"journal":{"name":"International Journal of Population Data Science","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46199487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring Goldstein et al.’s Scalelink method of data linkage. 探索Goldstein等人的Scalelink数据链接方法。
Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2022-08-25 DOI: 10.23889/ijpds.v7i3.2042
M. A. M. Cleaton, Josie Plachta, R. Shipsey
ObjectivesScalelink is an innovative probabilistic data linkage method based on correspondence analysis. Unlike the popular and widely-used Fellegi-Sunter algorithm, it does not assume linkage variable independence. It also claims to be more intuitive and computationally efficient. We aim to test this method for the first time on real-world big data. ApproachScalelink uses agreement states for each linkage variable and candidate pair. These are compared to determine how frequently, for all candidate pairs, any given agreement state is held at the same time as any other agreement state (this accounts for variable dependence). The results of this comparison are inputted into a loss function and the minimisation of this function is derived within constraints to produce weights. Currently, the method is accessible via Goldstein et al.’s paper and R package. We are translating it into PySpark to enable testing on datasets that are too large to link without using distributed computing. ResultsInitial testing of Goldstein et al.’s Scalelink method on small samples of real-world datasets shows that it performs as expected for a probabilistic linkage method, although cannot currently deal with missingness. To test the quality of the method on real-world big data, a high-quality linked dataset of the 2021 England and Wales Census and follow-up Census Coverage Survey will be used as a Gold Standard (GS). After developing a method that enables Scalelink to deal with missingness, we will apply Scalelink and automatic Fellegi-Sunter probabilistic linkage to this GS. We can thus establish and compare the precision and recall of both methods. We will also investigate linkage bias for particular demographics, test computational efficiency and estimate the clerical review burden for each method. ConclusionGoldstein et al.’s Scalelink algorithm shows promise as a high quality, scalable, dependence-free linkage algorithm for use in any matching project. Here, for the first time, we research the method’s quality and feasibility with real-world big data. From this we will produce recommendations regarding its utility.
目的scalelink是一种基于对应分析的概率数据链接方法。与流行且广泛使用的Fellegi-Sunter算法不同,它不假设连杆变量独立。它还声称更直观,计算效率更高。我们的目标是在现实世界的大数据上首次测试这种方法。ApproachScalelink为每个链接变量和候选对使用一致状态。对它们进行比较,以确定对于所有候选对,任何给定的协议状态与任何其他协议状态同时保持的频率(这说明了变量依赖性)。该比较的结果被输入到损失函数中,并且该函数的最小化在约束内导出以产生权重。目前,该方法可通过Goldstein等人的论文和R包访问。我们正在将其转换为PySpark,以便在不使用分布式计算就无法链接的数据集上进行测试。结果Goldstein等人的Scalelink方法在真实世界数据集的小样本上的初步测试表明,它的性能与概率链接方法的预期一样,尽管目前无法处理缺失。为了在真实世界的大数据上测试该方法的质量,2021年英格兰和威尔士人口普查和后续人口普查覆盖率调查的高质量关联数据集将被用作黄金标准(GS)。在开发出一种使Scalelink能够处理缺失的方法后,我们将把Scalelink和自动Fellegi-Sunter概率链接应用于该GS。因此,我们可以建立并比较这两种方法的精度和召回率。我们还将调查特定人口统计学的联系偏差,测试计算效率,并估计每种方法的文书审查负担。结论Goldstein等人的Scalelink算法有望成为一种高质量、可扩展、无依赖的链接算法,可用于任何匹配项目。在这里,我们首次利用真实世界的大数据研究了该方法的质量和可行性。据此,我们将提出关于其效用的建议。
{"title":"Exploring Goldstein et al.’s Scalelink method of data linkage.","authors":"M. A. M. Cleaton, Josie Plachta, R. Shipsey","doi":"10.23889/ijpds.v7i3.2042","DOIUrl":"https://doi.org/10.23889/ijpds.v7i3.2042","url":null,"abstract":"ObjectivesScalelink is an innovative probabilistic data linkage method based on correspondence analysis. Unlike the popular and widely-used Fellegi-Sunter algorithm, it does not assume linkage variable independence. It also claims to be more intuitive and computationally efficient. We aim to test this method for the first time on real-world big data. \u0000ApproachScalelink uses agreement states for each linkage variable and candidate pair. These are compared to determine how frequently, for all candidate pairs, any given agreement state is held at the same time as any other agreement state (this accounts for variable dependence). The results of this comparison are inputted into a loss function and the minimisation of this function is derived within constraints to produce weights. Currently, the method is accessible via Goldstein et al.’s paper and R package. We are translating it into PySpark to enable testing on datasets that are too large to link without using distributed computing. \u0000ResultsInitial testing of Goldstein et al.’s Scalelink method on small samples of real-world datasets shows that it performs as expected for a probabilistic linkage method, although cannot currently deal with missingness. To test the quality of the method on real-world big data, a high-quality linked dataset of the 2021 England and Wales Census and follow-up Census Coverage Survey will be used as a Gold Standard (GS). After developing a method that enables Scalelink to deal with missingness, we will apply Scalelink and automatic Fellegi-Sunter probabilistic linkage to this GS. We can thus establish and compare the precision and recall of both methods. We will also investigate linkage bias for particular demographics, test computational efficiency and estimate the clerical review burden for each method. \u0000ConclusionGoldstein et al.’s Scalelink algorithm shows promise as a high quality, scalable, dependence-free linkage algorithm for use in any matching project. Here, for the first time, we research the method’s quality and feasibility with real-world big data. From this we will produce recommendations regarding its utility.","PeriodicalId":36483,"journal":{"name":"International Journal of Population Data Science","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41432374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
COVID-19 vaccination rates and related outcomes in adults with intellectual and developmental disabilities (IDD): An application of linked administrative health data to support Ontario’s COVID-19 response. 患有智力和发育障碍(IDD)的成年人的新冠肺炎疫苗接种率和相关结果:应用相关行政健康数据支持安大略省应对新冠肺炎。
Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2022-08-25 DOI: 10.23889/ijpds.v7i3.2065
N. Troke, Diana An, Eliane Kim, Y. Lunsky, R. Balogh, L. Plumptre
ObjectivesEquitable vaccine distribution was essential in supporting Ontario’s COVID-19 response, particularly for persons with intellectual and developmental disabilities (IDD), who have been disproportionately impacted by the pandemic. An Applied Health Research Question (AHRQ) request through ICES, sought to report on COVID-19 vaccination uptake in adults with and without IDD. ApproachTo examine the proportion of adults with IDD vaccinated for COVID-19, a request from the Ministry of Children, Community and Social Services (MCCSS) was approved by the ICES-AHRQ team. A secondary goal was to explore if vaccinated individuals with IDD experienced similar levels of protection from COVID-19 infection, to the general population. The open cohort was derived by linking vaccination events reported in Ontario COVID-19 Vaccine Data, between December 2020 to December 2021, to several administrative health databases. An algorithm was used to define IDD by a series of inpatient hospitalizations, emergency department and/or physician visits, with IDD diagnostic codes. ResultsThe proportion who received at least two doses was similar between both groups (82% (IDD); 83% (non-IDD)). However, despite emerging evidence suggesting that high-risk populations should receive a third dose, a lower proportion of people with IDD (25%), compared to the general population without IDD (30%), had done so. The IDD subpopulation is generally younger, and partially explained the third dose findings when examined by age. Withal, adults with IDD vaccinated with at least two doses were mostly male (62% vs 48%), 18-29 years of age (44% vs 17%), and from the lowest neighborhood income quintile (26% vs 18%), compared to the non-IDD population, respectively. Cumulatively, adults with IDD had comparable rates of confirmed breakthrough case infections following vaccination (17%), to those without IDD (19%). Conclusion/ImplicationsAdministrative health data and analytics through the ICES-AHRQ program were used in responding to COVID-19, and providing public health guidance, for those with IDD. To inform decision making and policy actions related to immediate vaccination strategies, MCCSS used such findings to target vaccination efforts in specific IDD subpopulations, across Ontario.
目标公平的疫苗分配对于支持安大略省应对新冠肺炎至关重要,特别是对于受疫情影响过大的智力和发育障碍(IDD)患者。通过ICES提出的应用健康研究问题(AHRQ)请求旨在报告患有和不患有IDD的成年人接种新冠肺炎疫苗的情况。方法为了检查患有IDD的成年人接种新冠肺炎疫苗的比例,ICES-AHRQ团队批准了儿童、社区和社会服务部(MCCSS)的请求。第二个目标是探索接种疫苗的IDD患者对新冠肺炎感染的保护水平是否与普通人群相似。开放队列是通过将2020年12月至2021年12月期间安大略省新冠肺炎疫苗数据中报告的疫苗接种事件与几个行政卫生数据库联系起来得出的。通过一系列住院、急诊和/或医生就诊,使用IDD诊断代码,使用一种算法来定义IDD。结果两组患者中至少接受两剂治疗的比例相似(82%(IDD);83%(非IDD))。然而,尽管有新的证据表明高危人群应该接种第三剂,但与没有IDD的普通人群(30%)相比,患有IDD的人(25%)接种的比例较低。IDD亚群通常更年轻,并在按年龄检查时部分解释了第三剂的发现。与非IDD人群相比,至少接种两剂IDD疫苗的成年人大多为男性(62%对48%)、18-29岁(44%对17%)和社区收入最低的五分之一人群(26%对18%)。累计来看,患有IDD的成年人在接种疫苗后确诊的突破性病例感染率(17%)与没有IDD的人(19%)相当。结论/含义通过ICES-AHRQ计划进行的行政健康数据和分析用于应对新冠肺炎,并为IDD患者提供公共卫生指导。为了为与即时疫苗接种策略相关的决策和政策行动提供信息,MCCSS利用这些发现针对安大略省特定IDD亚群的疫苗接种工作。
{"title":"COVID-19 vaccination rates and related outcomes in adults with intellectual and developmental disabilities (IDD): An application of linked administrative health data to support Ontario’s COVID-19 response.","authors":"N. Troke, Diana An, Eliane Kim, Y. Lunsky, R. Balogh, L. Plumptre","doi":"10.23889/ijpds.v7i3.2065","DOIUrl":"https://doi.org/10.23889/ijpds.v7i3.2065","url":null,"abstract":"ObjectivesEquitable vaccine distribution was essential in supporting Ontario’s COVID-19 response, particularly for persons with intellectual and developmental disabilities (IDD), who have been disproportionately impacted by the pandemic. An Applied Health Research Question (AHRQ) request through ICES, sought to report on COVID-19 vaccination uptake in adults with and without IDD. \u0000ApproachTo examine the proportion of adults with IDD vaccinated for COVID-19, a request from the Ministry of Children, Community and Social Services (MCCSS) was approved by the ICES-AHRQ team. A secondary goal was to explore if vaccinated individuals with IDD experienced similar levels of protection from COVID-19 infection, to the general population. The open cohort was derived by linking vaccination events reported in Ontario COVID-19 Vaccine Data, between December 2020 to December 2021, to several administrative health databases. An algorithm was used to define IDD by a series of inpatient hospitalizations, emergency department and/or physician visits, with IDD diagnostic codes. \u0000ResultsThe proportion who received at least two doses was similar between both groups (82% (IDD); 83% (non-IDD)). However, despite emerging evidence suggesting that high-risk populations should receive a third dose, a lower proportion of people with IDD (25%), compared to the general population without IDD (30%), had done so. The IDD subpopulation is generally younger, and partially explained the third dose findings when examined by age. Withal, adults with IDD vaccinated with at least two doses were mostly male (62% vs 48%), 18-29 years of age (44% vs 17%), and from the lowest neighborhood income quintile (26% vs 18%), compared to the non-IDD population, respectively. Cumulatively, adults with IDD had comparable rates of confirmed breakthrough case infections following vaccination (17%), to those without IDD (19%). \u0000Conclusion/ImplicationsAdministrative health data and analytics through the ICES-AHRQ program were used in responding to COVID-19, and providing public health guidance, for those with IDD. To inform decision making and policy actions related to immediate vaccination strategies, MCCSS used such findings to target vaccination efforts in specific IDD subpopulations, across Ontario.","PeriodicalId":36483,"journal":{"name":"International Journal of Population Data Science","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42505134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Longitudinal study of diabetes prevalence and hospitalisations among care experienced and general population children in Scotland: evidence of an end of care “cliff edge”? 苏格兰有护理经验的儿童和普通人群儿童糖尿病患病率和住院率的纵向研究:护理“悬崖边缘”结束的证据?
Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2022-08-25 DOI: 10.23889/ijpds.v7i3.1998
M. Allik, A. Leyland, M. Henderson
ObjectivesCare experienced people have poorer health in UK and internationally, but the direction of causation is debated. Using longitudinal cross-sectoral data linkage we explore if inequalities in diabetes prevalence and hospitalisation are present before entering care or develop during or after leaving care. ApproachHealth and social care data were linked for 13,830 care experienced children (CEC) and together with 649,771 general population children (GPC) their prescriptions and hospitalisations were followed from birth between 1990-2004 to study end in 2016. Diabetes prevalence was estimated as at least one prescription   or inpatient hospitalisation for diabetes. We compared hospitalisation percentages and rates in the two cohorts by age and gender. Results from multivariable models adjusted for socioeconomic status, age, gender, care type/length, local authority, and comorbidities will be presented at conference. ResultsDiabetes prevalence was similar in both cohorts and higher in females. However, CEC had twice as many hospitalisations as GPC. Mean hospitalisations were highest among care experienced males (6 compared to 3.6 in females and 2 in GPC). 24% of CEC were hospitalised 3-9 times and 13% 10+ times, for GPC these were 19% and 3% respectively. Hospitalisation rates increase with age in both cohorts, as do differences between cohorts. At ages 0-4 hospitalisation rates are similar, by ages 12-15 CEC have twice as high and at ages 18-27 4-times higher hospitalisation rates. Among CEC, across all ages hospitalisation rates are lower while the child is in care, with the lowest rates in foster care. Hospitalisation rates are highest before entering and after leaving care. ConclusionResults for diabetes hospitalisations suggest that being in care can be good for children’s health. However, a sudden withdrawal of support can create a “cliff edge” and health may deteriorate after leaving care. Data linkage has significant potential to inform policy and practice, including supporting CEC after leaving care.
在英国和国际上,有护理经验的人健康状况较差,但因果关系的方向是有争议的。使用纵向跨部门数据链接,我们探索糖尿病患病率和住院治疗的不平等是否在进入护理之前存在,或在离开护理期间或之后发展。研究人员将13830名有护理经验的儿童(CEC)的健康和社会护理数据与649771名普通人群儿童(GPC)的数据联系起来,从1990-2004年出生到2016年研究结束,他们的处方和住院情况被跟踪。糖尿病患病率估计至少有一次处方或住院治疗糖尿病。我们按年龄和性别比较了两组患者的住院率和百分比。对社会经济地位、年龄、性别、护理类型/时间、地方当局和合并症进行调整的多变量模型的结果将在会议上发表。结果两组糖尿病患病率相似,女性患病率较高。然而,CEC的住院人数是GPC的两倍。有护理经验的男性平均住院率最高(6例,女性3.6例,GPC 2例)。24%的CEC患者住院3-9次,13%住院10次以上,GPC患者分别为19%和3%。两组患者的住院率随年龄增长而增加,两组患者之间的差异也是如此。0-4岁儿童的住院率相似,12-15岁儿童的住院率是原来的两倍,18-27岁儿童的住院率是原来的4倍。在CEC中,所有年龄段的儿童在接受照料期间的住院率都较低,其中寄养的住院率最低。入院前和出院后的住院率最高。结论糖尿病住院治疗的结果表明,护理对儿童健康有益。然而,突然停止支持可能会造成“悬崖边缘”,离开护理后健康状况可能会恶化。数据链接具有为政策和实践提供信息的巨大潜力,包括支持离开护理后的CEC。
{"title":"Longitudinal study of diabetes prevalence and hospitalisations among care experienced and general population children in Scotland: evidence of an end of care “cliff edge”?","authors":"M. Allik, A. Leyland, M. Henderson","doi":"10.23889/ijpds.v7i3.1998","DOIUrl":"https://doi.org/10.23889/ijpds.v7i3.1998","url":null,"abstract":"ObjectivesCare experienced people have poorer health in UK and internationally, but the direction of causation is debated. Using longitudinal cross-sectoral data linkage we explore if inequalities in diabetes prevalence and hospitalisation are present before entering care or develop during or after leaving care. \u0000ApproachHealth and social care data were linked for 13,830 care experienced children (CEC) and together with 649,771 general population children (GPC) their prescriptions and hospitalisations were followed from birth between 1990-2004 to study end in 2016. Diabetes prevalence was estimated as at least one prescription   or inpatient hospitalisation for diabetes. We compared hospitalisation percentages and rates in the two cohorts by age and gender. Results from multivariable models adjusted for socioeconomic status, age, gender, care type/length, local authority, and comorbidities will be presented at conference. \u0000ResultsDiabetes prevalence was similar in both cohorts and higher in females. However, CEC had twice as many hospitalisations as GPC. Mean hospitalisations were highest among care experienced males (6 compared to 3.6 in females and 2 in GPC). 24% of CEC were hospitalised 3-9 times and 13% 10+ times, for GPC these were 19% and 3% respectively. Hospitalisation rates increase with age in both cohorts, as do differences between cohorts. At ages 0-4 hospitalisation rates are similar, by ages 12-15 CEC have twice as high and at ages 18-27 4-times higher hospitalisation rates. Among CEC, across all ages hospitalisation rates are lower while the child is in care, with the lowest rates in foster care. Hospitalisation rates are highest before entering and after leaving care. \u0000ConclusionResults for diabetes hospitalisations suggest that being in care can be good for children’s health. However, a sudden withdrawal of support can create a “cliff edge” and health may deteriorate after leaving care. Data linkage has significant potential to inform policy and practice, including supporting CEC after leaving care.","PeriodicalId":36483,"journal":{"name":"International Journal of Population Data Science","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44664660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Maternal mental health and children’s development: a bi-directional relationship? 母亲心理健康与儿童发展:双向关系?
Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2022-08-25 DOI: 10.23889/ijpds.v7i3.1936
E. Lowthian, S. Bedston, A. Akbari, Alan Katz, K. Huxley, Rhodri D Johnson, S. M. Kristensen, R. Owen, Chris Taylor, L. Griffiths
ObjectivesResearch on bi-directional associations between self-reported caregiver mental health and child development is mixed. Through linkage of a cohort study and primary care data, we examine whether maternal mental health diagnoses, treatment and symptoms are bi-directionally associated with child development, namely emotional and conduct problems, hyperactivity and peer problems. ApproachWe accessed 14 years of data by linking the Millennium Cohort Study (in Wales) to anonymised individual-level population-scale health and administrative data within the Secure Anonymised Information Linkage (SAIL) Databank. We identified maternal mental health problems using John et al’s (2016) existing algorithm for anxiety and depression diagnoses, symptoms and treatment. We measured child development using parent-reports of the Strengths and Difficulties questionnaire. Outcomes were tested when the child was 3, 5, 7, 11 and 14 years of age. We used Bayesian Structural Equation Modelling, specifically Random-Intercept Cross-Lagged Panel Models, to analyse within and between-person associations. ResultsWe found that mother’s mental health was strongly associated over time, as were children’s development difficulties. Cross-lagged associations from mother to child were weakly positively associated at age 3 to 5 for child total scores, and at age 11 to 14 for child emotional problems. In contrast, child development associations with maternal mental health were significant from age 7 to 11 for total scores, emotional and peer problems, but weakly associated at age 3 to 5, and 11 to 14 for conduct problems. Hyperactivity had few associations. Few associations at the same-time point were found, but emotional problems at age 11 and 14 were positively associated, as were hyperactivity at age 14, and peer problems at age 11. Between-person effects were consistently strongly associated. ConclusionWe find mixed evidence for bi-directional associations, but strong between-person associations. Overall development and emotional problem models showed more bi-directional relationships; child development was positively associated with mother’s mental health event at age 7 for all models except hyperactivity, conduct problems were weakly associated at age 5 and 11.
目的研究自我报告照料者心理健康与儿童发展之间的双向关系。通过一项队列研究和初级保健数据的联系,我们研究了母亲心理健康的诊断、治疗和症状是否与儿童发育双向相关,即情绪和行为问题、多动和同伴问题。方法:我们通过将千年队列研究(威尔士)与安全匿名信息链接(SAIL)数据库中的匿名个人层面人口规模的健康和管理数据联系起来,访问了14年的数据。我们使用John等人(2016)现有的焦虑和抑郁诊断、症状和治疗算法来确定孕产妇心理健康问题。我们使用家长报告的优势和困难问卷来衡量儿童的发展。在孩子3岁、5岁、7岁、11岁和14岁时对结果进行了测试。我们使用贝叶斯结构方程模型,特别是随机截距交叉滞后面板模型,来分析人与人之间和人与人之间的联系。结果我们发现,母亲的心理健康与儿童的发展困难密切相关。母亲对孩子的交叉滞后关联在3 - 5岁儿童总分和11 - 14岁儿童情绪问题上呈弱正相关。相比之下,儿童发展与母亲心理健康的关联在7至11岁的总分、情绪和同伴问题上显著,但在3至5岁和11至14岁的行为问题上相关性较弱。多动几乎没有关联。在同一时间点上发现的联系很少,但11岁和14岁时的情绪问题呈正相关,14岁时的多动症和11岁时的同伴问题也是如此。人与人之间的影响始终密切相关。结论我们发现双向关联的证据不一,但人与人之间的关联很强。整体发展模型和情绪问题模型表现出更多的双向关系;儿童发展与母亲7岁时的心理健康事件呈正相关,除了多动症,行为问题在5岁和11岁时呈弱相关。
{"title":"Maternal mental health and children’s development: a bi-directional relationship?","authors":"E. Lowthian, S. Bedston, A. Akbari, Alan Katz, K. Huxley, Rhodri D Johnson, S. M. Kristensen, R. Owen, Chris Taylor, L. Griffiths","doi":"10.23889/ijpds.v7i3.1936","DOIUrl":"https://doi.org/10.23889/ijpds.v7i3.1936","url":null,"abstract":"ObjectivesResearch on bi-directional associations between self-reported caregiver mental health and child development is mixed. Through linkage of a cohort study and primary care data, we examine whether maternal mental health diagnoses, treatment and symptoms are bi-directionally associated with child development, namely emotional and conduct problems, hyperactivity and peer problems. \u0000ApproachWe accessed 14 years of data by linking the Millennium Cohort Study (in Wales) to anonymised individual-level population-scale health and administrative data within the Secure Anonymised Information Linkage (SAIL) Databank. We identified maternal mental health problems using John et al’s (2016) existing algorithm for anxiety and depression diagnoses, symptoms and treatment. We measured child development using parent-reports of the Strengths and Difficulties questionnaire. Outcomes were tested when the child was 3, 5, 7, 11 and 14 years of age. We used Bayesian Structural Equation Modelling, specifically Random-Intercept Cross-Lagged Panel Models, to analyse within and between-person associations. \u0000ResultsWe found that mother’s mental health was strongly associated over time, as were children’s development difficulties. Cross-lagged associations from mother to child were weakly positively associated at age 3 to 5 for child total scores, and at age 11 to 14 for child emotional problems. In contrast, child development associations with maternal mental health were significant from age 7 to 11 for total scores, emotional and peer problems, but weakly associated at age 3 to 5, and 11 to 14 for conduct problems. Hyperactivity had few associations. Few associations at the same-time point were found, but emotional problems at age 11 and 14 were positively associated, as were hyperactivity at age 14, and peer problems at age 11. Between-person effects were consistently strongly associated. \u0000ConclusionWe find mixed evidence for bi-directional associations, but strong between-person associations. Overall development and emotional problem models showed more bi-directional relationships; child development was positively associated with mother’s mental health event at age 7 for all models except hyperactivity, conduct problems were weakly associated at age 5 and 11.","PeriodicalId":36483,"journal":{"name":"International Journal of Population Data Science","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44827953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
International Journal of Population Data Science
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1