Pub Date : 2021-06-29DOI: 10.3329/dshj.v36i2.54393
M. Mamun, M. Hussain, R. Rima
While the global coronavirus crisis worsens, a surprising feature of the disease appears that children might be immune from the worst form of it. Studies suggest that COVID- 19 is more likely to infect older adult men, particularly those with comorbidities. There is only limited data detailing the effects of COVID-19 on the pediatric population. Patients with underlying cardiovascular comorbidities are at increased risk of morbidity and mortality from SARS-CoV-2 infection. Certain adult patients with congenital heart disease (ACHD) and with complex congenital heart disease can be considered as high risk for complications related to COVID-19 infection on the basis of decreased functional reserve. While no study on COVID-19 has been included paediatric patients with congenital heart disease, it stands to reason that patients with congenital heart disease can be considered at higher risk for complications from COVID-19. Given the increased risk for severe COVID-19 in adults with underlying cardiac disease, there is concern that patients with congenital heart disease (CHD) may likewise be at increased risk for severe infection, as they are known to have higher risk for complications with viral illnesses including respiratory syncytial virus and influenza. DS (Child) H J 2020; 36(2): 138-145
{"title":"COVID-19 and Children with Congenital Heart Disease: Pandemic Implication","authors":"M. Mamun, M. Hussain, R. Rima","doi":"10.3329/dshj.v36i2.54393","DOIUrl":"https://doi.org/10.3329/dshj.v36i2.54393","url":null,"abstract":"While the global coronavirus crisis worsens, a surprising feature of the disease appears that children might be immune from the worst form of it. Studies suggest that COVID- 19 is more likely to infect older adult men, particularly those with comorbidities. There is only limited data detailing the effects of COVID-19 on the pediatric population. Patients with underlying cardiovascular comorbidities are at increased risk of morbidity and mortality from SARS-CoV-2 infection. Certain adult patients with congenital heart disease (ACHD) and with complex congenital heart disease can be considered as high risk for complications related to COVID-19 infection on the basis of decreased functional reserve. While no study on COVID-19 has been included paediatric patients with congenital heart disease, it stands to reason that patients with congenital heart disease can be considered at higher risk for complications from COVID-19. Given the increased risk for severe COVID-19 in adults with underlying cardiac disease, there is concern that patients with congenital heart disease (CHD) may likewise be at increased risk for severe infection, as they are known to have higher risk for complications with viral illnesses including respiratory syncytial virus and influenza. \u0000DS (Child) H J 2020; 36(2): 138-145","PeriodicalId":364860,"journal":{"name":"Dhaka Shishu (Children) Hospital Journal","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127928016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-03-26DOI: 10.3329/DSHJ.V36I1.52619
R. Biswas, R. Islam
Background: There is increased risk of hearing impairment in children with congenital hypothyroidism (CH). Only a few studies have explored the prevalence of hearing impairment in CH and their results vary widely. There is no data of hearing impairment in Bangladeshi children with CH. Objectives: The aim of this study was to investigate the prevalence of hearing impairment in children with CH, and its relation with age of diagnosis and the dose of thyroxine (T4) they received. Methods: This study was conducted in Paediatric Endocrinology & Metabolic Disorder Department of Dhaka Shishu (Children) Hospital from July 2014 to December 2018. Hearing evaluation of 55 children diagnosed with CH was performed with a battery of tools that included Middle ear analysis, Pure Tone Audiometry (PTA), Behavioral Observation Audiometry (BOA) and Oto Acoustic Emissions (OAE). The choice of assessment tool was based on patient’s age. Results: The mean age at diagnosis and at inclusion into the study was 2.0±1.7 years and 3.2±2.3 years respectively. The etiological diagnosis was thyroid agenesis in 40(72.7%), ectopia in 3(5.5%), dyshormonogenesis in 7(12.7%) and hypothyroidism with eutopic gland in 5(9.1%%) patients. Middle ear analysis, PTA, BOA and OAE was done in 35, 28, 32 and 37 patients respectively. Sensorineural hearing loss was detected in 1 out of 55(1.8%) patients while conductive hearing loss was found in 3(5.4%) patients. Conclusion: Hearing loss was present in a small proportion of patients with permanent CH. Further larger studies are required to determine the exact prevalence of hearing impairment in Bangladeshi children with CH. DS (Child) H J 2020; 36(1) : 14-19
{"title":"Hearing Impairment in Children with Congenital Hypothyroidism","authors":"R. Biswas, R. Islam","doi":"10.3329/DSHJ.V36I1.52619","DOIUrl":"https://doi.org/10.3329/DSHJ.V36I1.52619","url":null,"abstract":"Background: There is increased risk of hearing impairment in children with congenital hypothyroidism (CH). Only a few studies have explored the prevalence of hearing impairment in CH and their results vary widely. There is no data of hearing impairment in Bangladeshi children with CH. \u0000Objectives: The aim of this study was to investigate the prevalence of hearing impairment in children with CH, and its relation with age of diagnosis and the dose of thyroxine (T4) they received. \u0000Methods: This study was conducted in Paediatric Endocrinology & Metabolic Disorder Department of Dhaka Shishu (Children) Hospital from July 2014 to December 2018. Hearing evaluation of 55 children diagnosed with CH was performed with a battery of tools that included Middle ear analysis, Pure Tone Audiometry (PTA), Behavioral Observation Audiometry (BOA) and Oto Acoustic Emissions (OAE). The choice of assessment tool was based on patient’s age. \u0000Results: The mean age at diagnosis and at inclusion into the study was 2.0±1.7 years and 3.2±2.3 years respectively. The etiological diagnosis was thyroid agenesis in 40(72.7%), ectopia in 3(5.5%), dyshormonogenesis in 7(12.7%) and hypothyroidism with eutopic gland in 5(9.1%%) patients. Middle ear analysis, PTA, BOA and OAE was done in 35, 28, 32 and 37 patients respectively. Sensorineural hearing loss was detected in 1 out of 55(1.8%) patients while conductive hearing loss was found in 3(5.4%) patients. \u0000Conclusion: Hearing loss was present in a small proportion of patients with permanent CH. Further larger studies are required to determine the exact prevalence of hearing impairment in Bangladeshi children with CH. \u0000DS (Child) H J 2020; 36(1) : 14-19","PeriodicalId":364860,"journal":{"name":"Dhaka Shishu (Children) Hospital Journal","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117191340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-02-03DOI: 10.3329/dshj.v34i1.51818
S. Afroz
Abstract not available DS (Child) H J 2018; 34(1) : 1-2
摘要:未得到DS(儿童)[J] 2018;34(1): 1-2
{"title":"Neonatal Acute Kidney Injury - Do We Need to Pay More Attention?","authors":"S. Afroz","doi":"10.3329/dshj.v34i1.51818","DOIUrl":"https://doi.org/10.3329/dshj.v34i1.51818","url":null,"abstract":"Abstract not available \u0000DS (Child) H J 2018; 34(1) : 1-2","PeriodicalId":364860,"journal":{"name":"Dhaka Shishu (Children) Hospital Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128675424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-02-03DOI: 10.3329/dshj.v34i1.51822
T. Ferdaus, S. Afroz, Md. Abid Hossain Mollah, M. Banerjee, Tofazzal Hossain Khan
Background: Acute kidney injury (AKI) is common in neonates admitted in Special Care Baby Unit (SCABU) with high morbidity and mortality. Objective: The present study was intended to see the immediate hospital outcome of neonatal acute kidney injury (AKI) in a Special Care Baby Unit (SCABU). Methods: This observational study was carried out in SCABU, in the Department of Paediatrics, Dhaka Medical College Hospital, from October 2013 to March 2014. A total of 44 neonates (from 3-28 days) with AKI were included in this study. AKI staging was done by using pediatric RIFLE criteria as Risk, Injury, Failure. Patients were managed conservatively and immediate hospital outcome was assessed by SCABU stay, multiorgan failure, resolution of AKI, mortality and dialysis as needed. Results: Demographic profile among the study population the neonate of d”7 days old comprised the main bulk. Majority of the neonates were of average birth weight. The diagnosis was based on estimated creatinine clearance(eCCL) criteria of pRIFLE showed that 40.9% neonates were at risk of AKI, 20.5% have had already injured. Higher proportions of neonates were classified as failure (38.6%).Outcome variables of neonatal AKI predicted by pRIFLE criteria was significantly higher in failure group in respect to SCABU stay (12.1+ 7.9) p value < 0.001, multiorgan failure (41.2 %) p value 0.026 and dialysis needed (88.2 %) p value < 0.001, resolution from AKI (47.1%) p value 0.885, Mortality (41.2%) p value 0.106. Here 43% neonates with AKI were improved with normal renal function and 29% improved with impaired renal function. Increased frequency of death (28%) in this series was due to multiorgan involvement and significantly higher in failure group with adequate dialysis support. Conclusion: From the findings of the study it can be concluded that immediate hospital outcome of neonatal AKI is worst even after adequate dialysis support. Multiorgan involvements, increase length of hospital stay at SCABU, increase need for dialysis, are the important cause of increase mortality and morbidity. So, early detection, prompt referral and immediate supportive therapy could improve the outcome of neonatal AKI. DS (Child) H J 2018; 34(1) : 5-10
{"title":"Outcome of Neonatal Acute Kidney Injury in a Special Care Baby Unit (SCABU)","authors":"T. Ferdaus, S. Afroz, Md. Abid Hossain Mollah, M. Banerjee, Tofazzal Hossain Khan","doi":"10.3329/dshj.v34i1.51822","DOIUrl":"https://doi.org/10.3329/dshj.v34i1.51822","url":null,"abstract":"Background: Acute kidney injury (AKI) is common in neonates admitted in Special Care Baby Unit (SCABU) with high morbidity and mortality. \u0000Objective: The present study was intended to see the immediate hospital outcome of neonatal acute kidney injury (AKI) in a Special Care Baby Unit (SCABU). \u0000Methods: This observational study was carried out in SCABU, in the Department of Paediatrics, Dhaka Medical College Hospital, from October 2013 to March 2014. A total of 44 neonates (from 3-28 days) with AKI were included in this study. AKI staging was done by using pediatric RIFLE criteria as Risk, Injury, Failure. Patients were managed conservatively and immediate hospital outcome was assessed by SCABU stay, multiorgan failure, resolution of AKI, mortality and dialysis as needed. \u0000Results: Demographic profile among the study population the neonate of d”7 days old comprised the main bulk. Majority of the neonates were of average birth weight. The diagnosis was based on estimated creatinine clearance(eCCL) criteria of pRIFLE showed that 40.9% neonates were at risk of AKI, 20.5% have had already injured. Higher proportions of neonates were classified as failure (38.6%).Outcome variables of neonatal AKI predicted by pRIFLE criteria was significantly higher in failure group in respect to SCABU stay (12.1+ 7.9) p value < 0.001, multiorgan failure (41.2 %) p value 0.026 and dialysis needed (88.2 %) p value < 0.001, resolution from AKI (47.1%) p value 0.885, Mortality (41.2%) p value 0.106. Here 43% neonates with AKI were improved with normal renal function and 29% improved with impaired renal function. Increased frequency of death (28%) in this series was due to multiorgan involvement and significantly higher in failure group with adequate dialysis support. \u0000Conclusion: From the findings of the study it can be concluded that immediate hospital outcome of neonatal AKI is worst even after adequate dialysis support. Multiorgan involvements, increase length of hospital stay at SCABU, increase need for dialysis, are the important cause of increase mortality and morbidity. So, early detection, prompt referral and immediate supportive therapy could improve the outcome of neonatal AKI. \u0000DS (Child) H J 2018; 34(1) : 5-10","PeriodicalId":364860,"journal":{"name":"Dhaka Shishu (Children) Hospital Journal","volume":"165 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121168017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-02-03DOI: 10.3329/dshj.v34i1.51828
P. Sarkar, Md Shakibur Rahman
In 1774, Joseph Priestley of England discovered the colorless, odorless, tasteless gas that Antoine Lavoisier named oxygen.Oxygen is a lifesaving drug has safe dose ranges, adverse physiologic effects, and toxic manifestations that are associated with higher doses and prolonged use. So, the administration of oxygen should be done with as much care and attention as any other drugs. Oxygen is transported in the blood in two ways: dissolved in the serum and in combination with hemoglobin.Children with any of the following signs are likely to have hypoxemia: central cyanosis, nasal flaring, inability to drink or feed due to respiratory distress, grunting with every breath and depressed mental state, severe lower chest wall indrawing, tachypnea or head nodding. The sources of oxygen and its delivery depend on the facility and the availability of resources. Most commonly use devices for oxygen delivery are nasal cannula, nasal prongs, simple face mask. An FiO2 of >0.5 is considered toxic. After only a few hours of breathing 100% O2, mucociliary function is depressed and clearance of mucous is impaired followed by nonproductive cough, substernal pain and nasal stuffiness may develop. More prolonged exposure to high O2 tention may lead to changes in the lung that mimic adult respiratory distress syndrome. In premature neonates, lower SpO2 may be targeted to reduce the toxic effects of oxygen therapy, such as retinopathy of prematurity or bronchopulmonary dysplasia. DS (Child) H J 2018; 34(1) : 48-54
{"title":"Oxygen Therapy in Children - An Update","authors":"P. Sarkar, Md Shakibur Rahman","doi":"10.3329/dshj.v34i1.51828","DOIUrl":"https://doi.org/10.3329/dshj.v34i1.51828","url":null,"abstract":"In 1774, Joseph Priestley of England discovered the colorless, odorless, tasteless gas that Antoine Lavoisier named oxygen.Oxygen is a lifesaving drug has safe dose ranges, adverse physiologic effects, and toxic manifestations that are associated with higher doses and prolonged use. So, the administration of oxygen should be done with as much care and attention as any other drugs. Oxygen is transported in the blood in two ways: dissolved in the serum and in combination with hemoglobin.Children with any of the following signs are likely to have hypoxemia: central cyanosis, nasal flaring, inability to drink or feed due to respiratory distress, grunting with every breath and depressed mental state, severe lower chest wall indrawing, tachypnea or head nodding. The sources of oxygen and its delivery depend on the facility and the availability of resources. Most commonly use devices for oxygen delivery are nasal cannula, nasal prongs, simple face mask. An FiO2 of >0.5 is considered toxic. After only a few hours of breathing 100% O2, mucociliary function is depressed and clearance of mucous is impaired followed by nonproductive cough, substernal pain and nasal stuffiness may develop. More prolonged exposure to high O2 tention may lead to changes in the lung that mimic adult respiratory distress syndrome. In premature neonates, lower SpO2 may be targeted to reduce the toxic effects of oxygen therapy, such as retinopathy of prematurity or bronchopulmonary dysplasia. \u0000DS (Child) H J 2018; 34(1) : 48-54","PeriodicalId":364860,"journal":{"name":"Dhaka Shishu (Children) Hospital Journal","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126619402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-02-03DOI: 10.3329/dshj.v34i1.51819
Md. Shahidul Islam
Abstract not available DS (Child) H J 2018; 34(1) : 3-4
摘要:未得到DS(儿童)[J] 2018;34(1): 3-4
{"title":"History of Pediatric Anesthesia in Bangladesh","authors":"Md. Shahidul Islam","doi":"10.3329/dshj.v34i1.51819","DOIUrl":"https://doi.org/10.3329/dshj.v34i1.51819","url":null,"abstract":"Abstract not available \u0000DS (Child) H J 2018; 34(1) : 3-4","PeriodicalId":364860,"journal":{"name":"Dhaka Shishu (Children) Hospital Journal","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127545185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-02-03DOI: 10.3329/dshj.v34i1.51827
-. Mohammad Ali, M. Selimuzzaman, Sumaya Marzan
Dental practitioners must be aware of the importance of bleeding disorders in the management of dental patients. Initial recognition of such bleeding disorders, knowledge of their possible systemic causes and clear idea in the management of the cases for dental treatment or when to refer those cases to secondary care, plays a crucial and important role in reducing potential complications and negative side effects. The purpose of this article is to review common bleeding disorders, complications and their management that dentists might find in their daily dental practice. DS (Child) H J 2018; 34(1) : 41-47
{"title":"Importance of Bleeding Disorder in the Management of Dental Patients","authors":"-. Mohammad Ali, M. Selimuzzaman, Sumaya Marzan","doi":"10.3329/dshj.v34i1.51827","DOIUrl":"https://doi.org/10.3329/dshj.v34i1.51827","url":null,"abstract":"Dental practitioners must be aware of the importance of bleeding disorders in the management of dental patients. Initial recognition of such bleeding disorders, knowledge of their possible systemic causes and clear idea in the management of the cases for dental treatment or when to refer those cases to secondary care, plays a crucial and important role in reducing potential complications and negative side effects. The purpose of this article is to review common bleeding disorders, complications and their management that dentists might find in their daily dental practice. \u0000DS (Child) H J 2018; 34(1) : 41-47","PeriodicalId":364860,"journal":{"name":"Dhaka Shishu (Children) Hospital Journal","volume":"339 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123215593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-02-03DOI: 10.3329/dshj.v34i1.51826
Md. Shafiul Hoque, Md Abdul Kaium Masud, A. N. Ahmed
Background: Guillain-Barré Syndrome (GBS) deserves a serious attention in children. The treatment of GBS consists of supportive and immune-modulator treatments, among which intravenous immunoglobulin (IVIG) is considered as most effective. But IVIG is costly and many patients cannot afford. Objective: To document the outcome of treatment of GBS patients by IVIG and Methylprednisolone. Methods: This is a retrospective study conducted in the Pediatric intensive care unit of Dhaka Shishu Hospital from January 2013 to December 2016. Data was collected from the admission record file in pediatric intensive care unit of Dhaka Shishu Hospital. A total of 36 patients up to the age of 15 years presenting with Guillain-Barré Syndrome were included in the study. Treatment modalities including supportive, Intravenous Immunoglobulins (IVIG) and steroids were selected in patients with GBS depending upon indication and facilities available. Those who were unable to provide IVIG due to financial constrain were treated with Methylprednisolone. Results were analyzed using SPSS (version 16) for Windows. Results: During the study period, a total of 36 patients were diagnosed and treated as GBS in pediatric intensive care unit. Among those, 34 (94.4%) patient were classical GBS. Most patients were in the age range of 3-5 years (21, 58.3%). Total 19 (52.8%) patients were treated with IVIG and rest was treated with steroid (17, 47.2%). 16 (44.4%) patient needed mechanical ventilation and among the patient needed mechanical ventilation 9 (56.3%) got treatment with IVIG and 7 (43.7%) got treatment with Methylprednisolone. After treatment 31 (86.2%) patients were improved and 5 (13.8%) were expired. Among the improved patient 16 (84.2%) were treated with IVIG and 15 (88.2%) were treated with Methylprednisolone. Conclusion: Treatment outcome of GBS patient with Methylprednisolone is comparable with IVIG and can be considered in case of financial constrain. DS (Child) H J 2018; 34(1) : 30-35
背景:吉兰-巴罗综合征(GBS)在儿童中值得重视。GBS的治疗包括支持治疗和免疫调节剂治疗，其中静脉注射免疫球蛋白(IVIG)被认为是最有效的。但是IVIG是昂贵的，许多患者负担不起。目的:观察IVIG联合甲基强的松龙治疗GBS患者的疗效。方法:对2013年1月至2016年12月在达卡石树医院儿科重症监护室进行回顾性研究。数据收集自达卡石树医院儿科重症监护病房的住院记录文件。共有36名年龄在15岁以下的格林-巴-罗综合征患者被纳入研究。治疗方式包括支持，静脉注射免疫球蛋白(IVIG)和类固醇的GBS患者选择根据指征和设施可用。那些由于经济拮据而无法提供IVIG的患者使用甲基强的松龙治疗。使用SPSS (version 16 for Windows)分析结果。结果:在研究期间，共有36例患儿在儿科重症监护室诊断和治疗为GBS。其中34例(94.4%)为典型GBS。大多数患者年龄在3 ~ 5岁(21.58.3%)。19例(52.8%)采用IVIG治疗，其余17例(47.2%)采用类固醇治疗。需要机械通气的患者16例(44.4%)，需要机械通气的患者中9例(56.3%)使用IVIG, 7例(43.7%)使用甲泼尼龙。治疗后好转31例(86.2%)，死亡5例(13.8%)。在好转的患者中，IVIG治疗16例(84.2%)，甲基强的松龙治疗15例(88.2%)。结论:甲强的松龙治疗GBS患者的效果与IVIG相当，在经济拮据的情况下可以考虑。DS(儿童)[J] 2018;34(1): 30-35
{"title":"Guillain-Barré Syndrome: Outcome of Treatment by IVIG vs. Methylprednisolone in Pediatric Intensive Care Unit of a Tertiary Care Hospital","authors":"Md. Shafiul Hoque, Md Abdul Kaium Masud, A. N. Ahmed","doi":"10.3329/dshj.v34i1.51826","DOIUrl":"https://doi.org/10.3329/dshj.v34i1.51826","url":null,"abstract":"Background: Guillain-Barré Syndrome (GBS) deserves a serious attention in children. The treatment of GBS consists of supportive and immune-modulator treatments, among which intravenous immunoglobulin (IVIG) is considered as most effective. But IVIG is costly and many patients cannot afford. \u0000Objective: To document the outcome of treatment of GBS patients by IVIG and Methylprednisolone. \u0000Methods: This is a retrospective study conducted in the Pediatric intensive care unit of Dhaka Shishu Hospital from January 2013 to December 2016. Data was collected from the admission record file in pediatric intensive care unit of Dhaka Shishu Hospital. A total of 36 patients up to the age of 15 years presenting with Guillain-Barré Syndrome were included in the study. Treatment modalities including supportive, Intravenous Immunoglobulins (IVIG) and steroids were selected in patients with GBS depending upon indication and facilities available. Those who were unable to provide IVIG due to financial constrain were treated with Methylprednisolone. Results were analyzed using SPSS (version 16) for Windows. \u0000Results: During the study period, a total of 36 patients were diagnosed and treated as GBS in pediatric intensive care unit. Among those, 34 (94.4%) patient were classical GBS. Most patients were in the age range of 3-5 years (21, 58.3%). Total 19 (52.8%) patients were treated with IVIG and rest was treated with steroid (17, 47.2%). 16 (44.4%) patient needed mechanical ventilation and among the patient needed mechanical ventilation 9 (56.3%) got treatment with IVIG and 7 (43.7%) got treatment with Methylprednisolone. After treatment 31 (86.2%) patients were improved and 5 (13.8%) were expired. Among the improved patient 16 (84.2%) were treated with IVIG and 15 (88.2%) were treated with Methylprednisolone. \u0000Conclusion: Treatment outcome of GBS patient with Methylprednisolone is comparable with IVIG and can be considered in case of financial constrain. \u0000DS (Child) H J 2018; 34(1) : 30-35","PeriodicalId":364860,"journal":{"name":"Dhaka Shishu (Children) Hospital Journal","volume":"119 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124613272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-02-03DOI: 10.3329/dshj.v34i1.51832
The Editor
Abstract not available DS (Child) H J 2018; 34(1) : 63-64
摘要:未得到DS(儿童)[J] 2018;34(1): 63-64
{"title":"Abstracts from current literature Vol 34(1)","authors":"The Editor","doi":"10.3329/dshj.v34i1.51832","DOIUrl":"https://doi.org/10.3329/dshj.v34i1.51832","url":null,"abstract":"Abstract not available \u0000DS (Child) H J 2018; 34(1) : 63-64","PeriodicalId":364860,"journal":{"name":"Dhaka Shishu (Children) Hospital Journal","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122031778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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