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The environmental responsibility of modern anesthesiology and perioperative care 现代麻醉学和围手术期护理的环境责任
Q3 Medicine Pub Date : 2024-02-21 DOI: 10.5554/22562087.e1103
J. A. Calvache
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引用次数: 0
Shortage of perioperative supplies and drugs: Theory and practical implications 围手术期用品和药品短缺:理论和实际影响
Q3 Medicine Pub Date : 2024-02-20 DOI: 10.5554/22562087.e1100
D. Rincón-Valenzuela, Ciro Gómez-Ardila
During the past three decades the world has been witness to an alarming increase in the shortage of drugs and biomedical products in the field of anesthesia and surgical care. This situation can be particularly challenging when there are no therapeutic alternatives available, as is the case with some supplies and drugs for perioperative use. Anesthesiologists, who play a crucial role in the preparation of the drugs they administer, are particularly aware of these shortages. The reasons for these shortages are diverse and involve problems in supply, demand and government regulation. Among the causes identified are the increase in demand, bidding systems and the sustainability challenges faced by pharmaceutical companies. It is essential to understand these causes in order to seek strategies to reduce the risk of shortages of medicines and supplies. Addressing this challenge requires improving supply chain management, fostering transparency in information on stock-outs, promoting local production of medicines, and strengthening procurement and distribution regulations and policies. The solution to this problem requires a comprehensive and collaborative approach, with multiple stakeholders working together to ensure adequate access to needed medications in the anesthesia and surgical care setting.
在过去的三十年里,全球麻醉和外科护理领域的药品和生物医药产品的短缺数量急剧增加。当没有替代治疗方法时,这种情况尤其具有挑战性,围术期使用的一些用品和药物就是如此。麻醉医师在配制药物方面发挥着至关重要的作用,他们尤其了解这些短缺情况。造成这些短缺的原因多种多样,涉及供应、需求和政府监管方面的问题。已查明的原因包括需求增加、招标制度和制药公司面临的可持续发展挑战。必须了解这些原因,才能寻求减少药品和供应短缺风险的策略。要应对这一挑战,就必须改善供应链管理,提高缺货信息的透明度,促进当地药品生产,加强采购和分销法规与政策。要解决这一问题,需要采取全面协作的方法,多个利益相关方共同努力,确保在麻醉和外科护理环境中充分获取所需药品。
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引用次数: 0
Características del paro cardiaco extrahospitalario atendido por operadores de ambulancias en Medellín. Estudio de cohorte retrospectivo de base poblacional 麦德林市由救护车操作员处理的院外心脏骤停患者的特征。基于人群的回顾性队列研究。
Q3 Medicine Pub Date : 2024-02-20 DOI: 10.5554/22562087.e1102
Sergio Andrés Muñoz Henao, Diego Ericson Giraldo Builes, Juan Carlos Villa Velásquez, Paola Andrea Elejalde Vidal, Carlos Eduardo Vallejo Bocanumen
Introduction: Every year, five million people around the world experience an out-of-hospital cardiac arrest (OHCA) and less than 40 % receive any assistance before the arrival of the Emergency Medical Services (EMS). Ambulance operators (AO) take care of people experiencing an OHCA, stabilize and then transfer them.  In Medellín, Colombia, there is a public AO and several private providers, but the information about an OHCA and the operational characteristics during the response to the event are limited. Objective: To estimate the incidence of OHCA and to explore the factors associated with survival after the event in Medellín city. Methods:  Retrospective, population-based cohort study. All the medical records of patients experiencing an OHCA who were assessed and treated by ambulance operators, (AO) of the Emergency Medical Services (EMS) and private agencies in Medellin city were reviewed. Descriptive statistics were used for data analysis and the annual incidence of the event standardized for the general population was estimated. Potential survival-associated factors reported as OR with their corresponding 95% CI were explored. Results: A total of 1,447 patient records with OHCA between 2018 and 2019 were analyzed.  The event incidence rate for the number of cases assessed was 28.1 (95 % CI 26.0-30.3) and 26.9 (95 % CI 24.9-29.1) cases per 100,000 inhabitants/year for 2018 and 2019, respectively; the incidence rate of treated OHCA was 2.6 (95 % CI 2.0-3.3) and 3.2 (95 % CI 2.5-4.0) per 100,000 inhabitants/year, for 2018 and 2019. Survival on arrival at hospitals of treated cases was 14.2 % (95 % CI 5.5-22.8) and 15.5 % (95 % CI 7.4-23.5) for 2018 and 2019, respectively. Conclusion: This study portrays the operating and care characteristics of the population experiencing OHCA in Medellín city. The incidence rate of the event and the survival were lower than those reported in the literature.
导言:全世界每年有 500 万人发生院外心脏骤停(OHCA),但只有不到 40% 的人在紧急医疗服务(EMS)到达之前得到了任何救助。救护车操作员(AO)负责救治院外心脏骤停患者,稳定病情,然后转运。 在哥伦比亚麦德林,有一家公共救护机构和几家私营救护机构,但有关心脏骤停的信息和救护过程中的操作特点却很有限。目标:估计麦德林市 OHCA 的发生率,并探讨与事件发生后存活率相关的因素。方法 基于人群的回顾性队列研究。研究人员查阅了麦德林市急救医疗服务机构(EMS)和私人机构的救护车操作员(AO)评估和治疗过的高危心梗患者的所有医疗记录。数据分析采用了描述性统计方法,并估算了以普通人群为标准的年发病率。研究还探讨了与生存相关的潜在因素,这些因素以 OR 形式报告,并附有相应的 95% CI。结果共分析了 2018 年至 2019 年间 1447 份 OHCA 患者记录。 2018 年和 2019 年,评估病例数的事件发生率分别为每 10 万居民/年 28.1 例(95 % CI 26.0-30.3)和 26.9 例(95 % CI 24.9-29.1);2018 年和 2019 年,接受治疗的 OHCA 发生率分别为每 10 万居民/年 2.6 例(95 % CI 2.0-3.3)和 3.2 例(95 % CI 2.5-4.0)。2018 年和 2019 年,接受治疗的病例到达医院后的存活率分别为 14.2 %(95 % CI 5.5-22.8)和 15.5 %(95 % CI 7.4-23.5)。结论:本研究描绘了麦德林市发生 OHCA 的人群的手术和护理特征。该事件的发生率和存活率均低于文献报道。
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引用次数: 0
Respuesta hemodinámica a dosis subanestésicas de ketamina en dolor posoperatorio: revisión sistemática 术后疼痛患者对亚麻醉剂量氯胺酮的血流动力学反应:系统综述
Q3 Medicine Pub Date : 2024-02-12 DOI: 10.5554/22562087.e1099
A. M. Cadavid Puentes, Julio Ernesto Camelo Rincón, Fabián David Casas Arroyave, Edna Fernanda Chávez Lasso, Maritza Leyton Ortega, Alejandro Tovar Gutiérrez
Introduction: Low-dose ketamine infusions have shown analgesic effectiveness for the management of postoperative pain. The impact of low-dose ketamine infusions on cardiovascular response is dose-dependent and requires a better knowledge about its effects on this population. Objective: To conduct a systematic review to describe changes in systolic, diastolic and mean arterial pressure, and heart rate 24, 48 and 72 hours after surgery. Methods: Randomized, controlled trials were reviewed in the  Cochrane Library, PubMed, EMBASE, SciELO, Lilacs and grey literature on low-dose ketamine infusions for the study variables. The quality of the studies was assessed using the Cochrane’s risk of bias tool. Results: Six randomized, controlled trials with 641 patients were included. Low-quality evidence was found suggestive of a lack of certainty of any significant differences in the systolic blood pressure variables at 24 hours (mean standard deviation  -1.00, 95 % CI: -7.27 to 5.27). A statistically significant higher mean heart rate at 24 hours was identified in the low-dose ketamine infusion group, (mean standard deviation 1.64 95 % CI: 0.38 to 2.90) which did not reach clinical significance. A lower pain level and less use of opioids was identified in the low-dose ketamine infusion group. Conclusion: Low quality evidence was found, suggesting that low-dose ketamine infusions are not associated with significant changes in blood pressure or heart rate 24 – 48 hours after surgery. It is important to individualize cardiovascular risk for each case, before initiating treatment.
简介:低剂量氯胺酮输注在治疗术后疼痛方面具有镇痛效果。低剂量氯胺酮输注对心血管反应的影响与剂量有关,因此需要更好地了解其对这一人群的影响。目的:开展一项系统性研究,描述术后 24、48 和 72 小时收缩压、舒张压、平均动脉压和心率的变化。方法:回顾随机对照试验:在 Cochrane 图书馆、PubMed、EMBASE、SciELO、Lilacs 和灰色文献中查阅了有关低剂量氯胺酮输注研究变量的随机对照试验。研究质量采用 Cochrane 的偏倚风险工具进行评估。研究结果共纳入了六项随机对照试验,641 名患者接受了治疗。发现的低质量证据表明,24 小时内收缩压变量的显著差异缺乏确定性(平均标准偏差-1.00,95% CI:-7.27 至 5.27)。低剂量氯胺酮输注组 24 小时平均心率较高,具有统计学意义(平均标准偏差 1.64,95 % CI:0.38 至 2.90),但未达到临床意义。低剂量氯胺酮输注组的疼痛程度较低,阿片类药物的使用也较少。结论低质量证据表明,低剂量氯胺酮输注与术后 24 - 48 小时血压或心率的显著变化无关。重要的是,在开始治疗之前,要针对每个病例的心血管风险进行个体化分析。
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引用次数: 0
ChatGPT's learning and reasoning capacity in anesthesiology ChatGPT 在麻醉学方面的学习和推理能力
Q3 Medicine Pub Date : 2023-11-17 DOI: 10.5554/22562087.e1092
Gustavo Cruz, Santiago Pedroza, Fredy Ariza
Introduction: Over the past few months, ChatGPT has raised a lot of interest given its ability to perform complex tasks through natural language and conversation. However, its use in clinical decision-making is limited and its application in the field of anesthesiology is unknown. Objective: To assess ChatGPT’s basic and clinical reasoning and its learning ability in a performance test on general and specific anesthesia topics. Methods: A three-phase assessment was conducted. Basic knowledge of anesthesia was assessed in the first phase, followed by a review of difficult airway management and, finally, measurement of decision-making ability in ten clinical cases. The second and the third phases were conducted before and after feeding ChatGPT with the 2022 guidelines of the American Society of Anesthesiologists on difficult airway management. Results: On average, ChatGPT succeded 65% of the time in the first phase and 48% of the time in the second phase. Agreement in clinical cases was 20%, with 90% relevance and 10% error rate. After learning, ChatGPT improved in the second phase, and was correct 59% of the time, with agreement in clinical cases also increasing to 40%. Conclusions: ChatGPT showed acceptable accuracy in the basic knowledge test, high relevance in the management of specific difficult airway clinical cases, and the ability to improve after learning.
简介在过去的几个月里,ChatGPT 通过自然语言和对话执行复杂任务的能力引起了人们的广泛兴趣。然而,它在临床决策中的应用有限,在麻醉学领域的应用更是未知数。 目的评估 ChatGPT 的基本推理和临床推理能力,以及其在普通和特殊麻醉主题性能测试中的学习能力。 方法:分三个阶段进行评估:评估分为三个阶段。第一阶段评估麻醉基础知识,随后复习困难气道处理,最后测量十个临床病例的决策能力。第二和第三阶段分别在喂食 ChatGPT 前和喂食 ChatGPT 后进行,采用的是美国麻醉医师协会关于困难气道处理的 2022 年指南。 结果:ChatGPT 在第一阶段的平均成功率为 65%,在第二阶段的平均成功率为 48%。临床病例的一致性为 20%,相关性为 90%,错误率为 10%。经过学习,ChatGPT 在第二阶段有所提高,正确率达到 59%,与临床病例的一致性也提高到 40%。 结论ChatGPT 在基础知识测试中表现出了可接受的准确性,在处理特定困难气道临床病例时具有很高的相关性,并且在学习后还能得到提高。
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引用次数: 0
Anesthesia training: Are we doing enough in three years? Cross-sectional study 麻醉培训:我们在三年内做得够多吗?横断面研究
Q3 Medicine Pub Date : 2023-11-15 DOI: 10.5554/22562087.e1091
María Paula Giraldo, Andrés Guillermo Beltrán, Julieth Díaz-Ramírez, German Andrés Franco-Gruntorad
Introduction: The minimum number of procedures required to be performed during anesthesia training has not been officially defined in Colombia. Although a number is no guarantee of acquired competencies, it does indicate the level of opportunity offered by the different programs. This study describes the practical training afforded to residents in a graduate anesthesia program in Colombia, and compares its results with international standards. Objective: Describe exposure to procedures performed by residents enrolled in a three-year anesthesia specialization program in Colombia between 2015 and 2020, and compare with the standards proposed by ASCOFAME and ACGME. Methods: Descriptive, cross-sectional study which included residents who did their specialization in a Colombian anesthesia program between 2015 and 2020. Complexity, anesthesia techniques, invasive monitoring and airway approach were described. Finally a descriptive comparison was made with the published references of the Colombian Association of Medical Schools (ASCOFAME) and the Accreditation Council for Graduate Medical Education (ACGME). Results: The results for 10 residents were included. Each resident had a median of 978 cases (IQR 942-1120), corresponding to 25 surgical specialties, the most frequent being general surgery (18%), orthopedics (16%), pediatric surgery (19%), and obstetrics (10.8%). According to the American Society of Anesthesiology (ASA) classification, the majority of patients were ASA II (39.63%) and ASA III (28.4%). Adequate exposure was achieved in 11 of the 15 categories proposed by ACGME and in 6 of the 15 proposed by ASCOFAME. Conclusions: A detailed description of the practice component acquired by the residents during their three years of training was obtained. This baseline provides insight into the national landscape and allows to describe the relationship with international standards.
导言:哥伦比亚尚未正式规定麻醉培训期间所需的最低手术数量。虽然数量并不能保证所获得的能力,但它确实表明了不同项目所提供的机会水平。本研究描述了哥伦比亚一个麻醉研究生项目为住院医师提供的实践培训,并将其结果与国际标准进行了比较。 目的:描述 2015 年至 2020 年间在哥伦比亚参加三年制麻醉专业课程的住院医师所接触的手术,并将其与 ASCOFAME 和 ACGME 提出的标准进行比较。 研究方法:描述性横断面研究,包括 2015 年至 2020 年期间在哥伦比亚麻醉专业学习的住院医师。对复杂性、麻醉技术、侵入性监测和气道方法进行了描述。最后,与哥伦比亚医学院协会(ASCOFAME)和毕业后医学教育认证委员会(ACGME)公布的参考文献进行了描述性比较。 结果:共纳入了 10 名住院医师的研究结果。每位住院医师的病例中位数为 978 例(IQR 942-1120),涉及 25 个外科专科,其中最常见的是普通外科(18%)、骨科(16%)、小儿外科(19%)和产科(10.8%)。根据美国麻醉学会(ASA)的分类,大多数患者属于ASA II级(39.63%)和ASA III级(28.4%)。在 ACGME 提出的 15 个分类中,有 11 个达到了充分暴露,在 ASCOFAME 提出的 15 个分类中,有 6 个达到了充分暴露。 结论:对住院医师在三年培训期间获得的实践内容进行了详细描述。这一基线有助于深入了解各国的情况,并能说明与国际标准之间的关系。
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引用次数: 0
Promises for the future: The role of artificial intelligence in education and perioperative care 对未来的承诺:人工智能在教育和围手术期护理中的作用
Q3 Medicine Pub Date : 2023-11-02 DOI: 10.5554/22562087.e1090
J. A. Calvache
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引用次数: 0
Postgraduate medical education in Colombia. Proposals to improve it 哥伦比亚的医学研究生教育。改进建议
Q3 Medicine Pub Date : 2023-10-30 DOI: 10.5554/22562087.e1089
José Ricardo Navarro-Vargas, Héctor Andrés Ruiz-Ávila, Hans Fred García–Araque
After 70 years of the formalization of medical specialties in Colombia, very little progress has been made in the educational models for the acquisition of clinical competencies in these postgraduate programs. Furthermore, although there is already a law on human resources in health, the Colombian medical education system lacks specific regulations on the training of health professionals (physicians) in the different medical specialty programs offered in the country. Likewise, at present, factors such as the financial crisis of public hospitals, the limited number of accredited hospitals and the growing number of medical schools and specialization programs, affect the comprehensive and equal development of medical competencies of professionals who are trained as specialists in the different postgraduate medical programs offered in Colombia.  In view of the above, the purpose of this article is to present a proposal for postgraduate medical education that prioritizes the adequate acquisition of competencies over compliance with the time required to complete the curricula of the different medical specialties. However, this involves several prerequisites: a regulatory body in charge of overseeing and monitoring the training of medical residents or specialists in the country; strong training in university teaching for professors practicing in medical schools and university hospitals; the standardization of the graduates profile; adequate financing of university hospitals, as well as appropriate support in the process of accreditation as such, and the self-evaluation and continuous improvement of postgraduate medical programs.
哥伦比亚的医学专业正规化已有 70 年,但在这些研究生课程中获取临床能力的教育模式方面进展甚微。 此外,虽然已经有了一部关于卫生人力资源的法律,但哥伦比亚的医学教育体系缺乏关于在国内提供的不同医学专业课程中培训卫生专业人员(医生)的具体规定。 同样,目前,公立医院的财政危机、获得认证的医院数量有限以及医学院和专业课程的数量不断增加等因素,都影响了在哥伦比亚提供的不同医学研究生课程中接受专业培训的专业人员的医疗能力的全面和平等发展。 有鉴于此,本文旨在提出一项关于医学研究生教育的建议,该建议将充分掌握能力置于完成不同医学专业课程所需的时间之上。然而,这涉及到几个先决条件:一个负责监督和监测国内住院医师或专科医生培训的监管机构;对在医学院和大学医院执业的教授进行强有力的大学教学培训;毕业生档案的标准化;为大学医院提供充足的资金,并在认证过程中提供适当的支持,以及对医学研究生课程进行自我评估和持续改进。
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引用次数: 0
The three main tasks of modern epidemiology: description, prediction and causal inference 现代流行病学的三大任务:描述、预测和因果推论
Q3 Medicine Pub Date : 2023-10-09 DOI: 10.5554/22562087.e1088
J. A. Calvache, César Higgins Tejera
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引用次数: 0
What are the effects of drugs for nausea and vomiting prevention following general anesthesia? Summary and comments regarding a Cochrane Collaboration network meta-analysis 全身麻醉后预防恶心和呕吐药物的效果如何?有关 Cochrane 协作网络荟萃分析的摘要和评论
Q3 Medicine Pub Date : 2023-09-14 DOI: 10.5554/22562087.e1087
M. Z. Zamudio Burbano, J. A. Calvache, I. Flórez
The aim of this special article is to summarize and discuss, from an anesthesia perspective, the network meta-analysis on drugs used for the prevention of postoperative nausea and vomiting after general anesthesia, in agreement with the Cochrane Colombia collaboration and within the framework of the Cochrane Corners strategy. Through the combination of indirect comparisons and based on the evidence, the use of aprepitant, ramosetron, granisetron, dexamethasone and ondansetron is recommended with a high degree of certainty for the reduction of postoperative nausea and vomiting.
这篇专文旨在从麻醉学的角度总结和讨论关于预防全身麻醉后恶心和呕吐药物的网络荟萃分析,该分析与 Cochrane 哥伦比亚合作组织达成一致,并在 Cochrane Corners 战略的框架内进行。通过结合间接比较和证据,阿普瑞坦、雷莫司琼、格拉司琼、地塞米松和昂丹司琼被高度肯定地推荐用于减少术后恶心和呕吐。
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引用次数: 0
期刊
Colombian Journal of Anesthesiology
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