首页 > 最新文献

Colombian Journal of Anesthesiology最新文献

英文 中文
Complications of bronchial thermoplasty using laryngeal mask: case series 喉罩支气管热成形术的并发症:病例系列
Q3 Medicine Pub Date : 2021-10-11 DOI: 10.5554/22562087.e1008
Carlos Fernando Sanabria Botello, A. Fernández Trujillo, I. Palacios, C. Ocampo
Severe asthma affects more than 250 million people and represents high healthcare costs. Bronchial thermoplasty is a relatively new technique in interventional pulmonology for managing this condition. The procedure is done under general anesthesia and the patients are mostly ASA II and III; therefore, the anesthesia plan must be safe. The purpose of the article is to describe the anesthetic technique used (general anesthesia and laryngeal mask) and the immediate and early complications of the procedure. Four patients were included, each undergoing three sessions. The complications during and immediately after the procedure, as well as the early complications (up to seven days post-procedure) that could have required hospital management were discussed. In three of the sessions at least one acute bronchospasm event presented, but only one patient required hospital admission for more than 24 hours. Experience suggests that thermoplasty may be safely conducted under general anesthesia and laryngeal mask.
严重哮喘影响超过2.5亿人,医疗费用高昂。支气管热成形术是介入肺科治疗这种疾病的一种相对较新的技术。手术是在全身麻醉下进行的,患者大多是ASA II和III;因此,麻醉方案必须是安全的。本文的目的是描述所使用的麻醉技术(全身麻醉和喉罩)以及手术的即时和早期并发症。包括四名患者,每个患者接受三次治疗。讨论了手术期间和手术后的并发症,以及可能需要医院管理的早期并发症(手术后七天)。在其中三个疗程中,至少出现了一例急性支气管痉挛事件,但只有一名患者需要住院超过24小时。经验表明,热成形术可以在全身麻醉和喉罩下安全进行。
{"title":"Complications of bronchial thermoplasty using laryngeal mask: case series","authors":"Carlos Fernando Sanabria Botello, A. Fernández Trujillo, I. Palacios, C. Ocampo","doi":"10.5554/22562087.e1008","DOIUrl":"https://doi.org/10.5554/22562087.e1008","url":null,"abstract":"Severe asthma affects more than 250 million people and represents high healthcare costs. Bronchial thermoplasty is a relatively new technique in interventional pulmonology for managing this condition. The procedure is done under general anesthesia and the patients are mostly ASA II and III; therefore, the anesthesia plan must be safe. The purpose of the article is to describe the anesthetic technique used (general anesthesia and laryngeal mask) and the immediate and early complications of the procedure. Four patients were included, each undergoing three sessions. The complications during and immediately after the procedure, as well as the early complications (up to seven days post-procedure) that could have required hospital management were discussed. In three of the sessions at least one acute bronchospasm event presented, but only one patient required hospital admission for more than 24 hours. Experience suggests that thermoplasty may be safely conducted under general anesthesia and laryngeal mask.","PeriodicalId":36529,"journal":{"name":"Colombian Journal of Anesthesiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44231115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Update on the management of local anesthetic systemic toxicity 局麻药全身毒性管理的最新进展
Q3 Medicine Pub Date : 2021-10-07 DOI: 10.5554/22562087.e1007
M. I. Berrío Valencia, Sebastián Rivera Díaz
{"title":"Update on the management of local anesthetic systemic toxicity","authors":"M. I. Berrío Valencia, Sebastián Rivera Díaz","doi":"10.5554/22562087.e1007","DOIUrl":"https://doi.org/10.5554/22562087.e1007","url":null,"abstract":"","PeriodicalId":36529,"journal":{"name":"Colombian Journal of Anesthesiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43036931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Aerosol box for intubation of patients with suspected COVID-19: simulation study 用于疑似新冠肺炎患者插管的气雾盒:模拟研究
Q3 Medicine Pub Date : 2021-10-04 DOI: 10.5554/22562087.e1006
Saúl Álvarez Robles, Claudia Consuelo Torres Contreras, Raquel Rivera Carvajal, Víctor Manuel Lucigniani Ariza, Sonia Margarita Vivas García
Introduction. Endotracheal intubation is a procedure associated with a high level of exposure to the COVID-19 virus. This has led to the search of alternatives to reduce the risk of contamination, including the so-called aerosol box. Objective: To compare time and difficulty of orotracheal intubation when using the aerosol box in a simulated setting. Methodology: Observational study conducted with the participation of 33 anesthetist physicians and anesthesia residents; groups were compared in terms of time and intubation difficulty using a conventional Macintosh laryngoscope and the McGRATH™ MAC (Medtronic) videolaryngoscope with or without aerosol box. In order to determine performance with the intubation maneuver, crude hazard ratios were estimated, and a Cox multivariate regression model was built, adjusted by anesthetist years of experience and difficulties during the procedure. Results: On average, the aerosol box increased intubation time by 7.57 seconds (SD 8.33) when the videolaryngoscope was used, and by 6.62 (SD 5.74) with the Macintosh. Overall, 132 intubations were performed, with 121 successful and 6 failed first-time attempts (4 with the use of the aerosol box); 16 participants (48.48%) reported difficulty handling the box. With the use of the Macintosh, intubation was found to be faster than with the videolaryngoscope (cHR: 1.36 [95% CI 0.64-2.88]; adjusted HR: 2.20 [95% CI 0.73-6.62]). Conclusions: The use of the aerosol box and personal protective equipment in a simulation setting hinders the intubation maneuver and may result in protracted execution time.
介绍气管插管是一种与高水平接触新冠肺炎病毒相关的程序。这导致了寻找降低污染风险的替代品,包括所谓的气溶胶盒。目的:比较在模拟环境中使用气雾盒进行经口气管插管的时间和难度。方法:由33名麻醉师、医生和麻醉住院医师参与的观察性研究;使用传统的Macintosh喉镜和McGRATH在时间和插管困难方面对各组进行了比较™ 带或不带气雾盒的MAC(美敦力)视频喉镜。为了确定插管操作的性能,估计了粗略的危险比,并建立了Cox多元回归模型,根据麻醉师多年的经验和手术过程中的困难进行了调整。结果:使用视频喉镜时,气雾盒平均增加插管时间7.57秒(SD 8.33),使用Macintosh时增加插管时间6.62秒(SD 5.74)。总共进行了132次插管,其中121次成功,6次失败(4次使用气雾盒);16名参与者(48.48%)表示难以处理箱子。使用Macintosh,插管比使用视频喉镜更快(cHR:1.36[95%CI 0.64-2.88];调整后HR:2.20[95%CI 0.73-6.62])。结论:在模拟环境中使用气雾盒和个人防护设备会阻碍插管操作,并可能导致执行时间延长。
{"title":"Aerosol box for intubation of patients with suspected COVID-19: simulation study","authors":"Saúl Álvarez Robles, Claudia Consuelo Torres Contreras, Raquel Rivera Carvajal, Víctor Manuel Lucigniani Ariza, Sonia Margarita Vivas García","doi":"10.5554/22562087.e1006","DOIUrl":"https://doi.org/10.5554/22562087.e1006","url":null,"abstract":"Introduction. Endotracheal intubation is a procedure associated with a high level of exposure to the COVID-19 virus. This has led to the search of alternatives to reduce the risk of contamination, including the so-called aerosol box. \u0000Objective: To compare time and difficulty of orotracheal intubation when using the aerosol box in a simulated setting. \u0000Methodology: Observational study conducted with the participation of 33 anesthetist physicians and anesthesia residents; groups were compared in terms of time and intubation difficulty using a conventional Macintosh laryngoscope and the McGRATH™ MAC (Medtronic) videolaryngoscope with or without aerosol box. In order to determine performance with the intubation maneuver, crude hazard ratios were estimated, and a Cox multivariate regression model was built, adjusted by anesthetist years of experience and difficulties during the procedure. \u0000Results: On average, the aerosol box increased intubation time by 7.57 seconds (SD 8.33) when the videolaryngoscope was used, and by 6.62 (SD 5.74) with the Macintosh. Overall, 132 intubations were performed, with 121 successful and 6 failed first-time attempts (4 with the use of the aerosol box); 16 participants (48.48%) reported difficulty handling the box. With the use of the Macintosh, intubation was found to be faster than with the videolaryngoscope (cHR: 1.36 [95% CI 0.64-2.88]; adjusted HR: 2.20 [95% CI 0.73-6.62]). \u0000Conclusions: The use of the aerosol box and personal protective equipment in a simulation setting hinders the intubation maneuver and may result in protracted execution time.","PeriodicalId":36529,"journal":{"name":"Colombian Journal of Anesthesiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47043886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Assessing the duration of obstetric analgesia and the time elapsed between analgesia and delivery. Observational trial 评估产科镇痛的持续时间和从镇痛到分娩的时间。观察试验
Q3 Medicine Pub Date : 2021-09-21 DOI: 10.5554/22562087.e1005
Juan Sebastián Parada Zuluaga, Diego Alejandro Bastidas Palacios, Yerlin Andrés Colina Vargas, Nury Isabel Socha García, J. G. Barrientos Gómez, Ancízar Joaquín De la Peña Silva
Introduction: The duration of labor and the immediate puerperium are affected by obstetric and maternal-fetal factors. Interventions to provide obstetric analgesia may prolong the hospital stay. Objective: To characterize the procedure for obstetric analgesia and describe the time elapsed between analgesia and delivery and postpartum surveillance in healthy mothers. Methods: Observational, descriptive trial. The time elapsed between analgesia and delivery, and postpartum surveillance were measured in healthy pregnant women with vaginal delivery and a prescription of a neuraxial analgesia technique. Results: 226 patients were included. The mean time elapsed between analgesia an delivery was 4 hours (IQR 3-7). 50.7 % (n = 114) received early analgesia (neuraxial technique with ≤ 4 centimeters of cervical dilatation), of which 48.2 % (n = 109) experienced a duration of analgesia until delivery longer than expected. The mean cervical dilatation at the time of the neuraxial approach was 4 centimeters (IQR 4-6) and the epidural technique was the most frequently used – 92.9 % (n = 210). The mean postpartum surveillance was 20 hours (IQR 15-27). Conclusions: Half of the patients included received early analgesia and around fifty percent of them took longer than expected in completing delivery. The postpartum surveillance time was consistent with the provisions of the Ministry of Health and with the current trend of a short postpartum surveillance aimed at early hospital discharge and the benefits thereof.
分娩持续时间和产褥期直接受到产科和母胎因素的影响。提供产科镇痛的干预措施可能延长住院时间。目的:描述健康母亲的产科镇痛过程,描述从镇痛到分娩和产后监测之间的时间间隔。方法:观察性描述性试验。在健康孕妇阴道分娩和神经轴镇痛技术处方中,测量了镇痛和分娩之间的时间间隔和产后监测。结果:纳入226例患者。从镇痛到分娩的平均时间为4小时(IQR 3-7)。50.7% (n = 114)接受了早期镇痛(宫颈扩张≤4厘米的轴向技术),其中48.2% (n = 109)的镇痛持续时间超过预期。神经轴入路时平均宫颈扩张4厘米(IQR 4-6),硬膜外技术是最常用的- 92.9% (n = 210)。平均产后监测时间为20小时(IQR 15-27)。结论:一半的患者接受了早期镇痛,大约50%的患者完成分娩的时间比预期的要长。产后监测时间符合卫生部的规定,也符合目前短期产后监测的趋势,目的是尽早出院并从中获益。
{"title":"Assessing the duration of obstetric analgesia and the time elapsed between analgesia and delivery. Observational trial","authors":"Juan Sebastián Parada Zuluaga, Diego Alejandro Bastidas Palacios, Yerlin Andrés Colina Vargas, Nury Isabel Socha García, J. G. Barrientos Gómez, Ancízar Joaquín De la Peña Silva","doi":"10.5554/22562087.e1005","DOIUrl":"https://doi.org/10.5554/22562087.e1005","url":null,"abstract":"Introduction: The duration of labor and the immediate puerperium are affected by obstetric and maternal-fetal factors. Interventions to provide obstetric analgesia may prolong the hospital stay. \u0000Objective: To characterize the procedure for obstetric analgesia and describe the time elapsed between analgesia and delivery and postpartum surveillance in healthy mothers. \u0000Methods: Observational, descriptive trial. The time elapsed between analgesia and delivery, and postpartum surveillance were measured in healthy pregnant women with vaginal delivery and a prescription of a neuraxial analgesia technique. \u0000Results: 226 patients were included. The mean time elapsed between analgesia an delivery was 4 hours (IQR 3-7). 50.7 % (n = 114) received early analgesia (neuraxial technique with ≤ 4 centimeters of cervical dilatation), of which 48.2 % (n = 109) experienced a duration of analgesia until delivery longer than expected. The mean cervical dilatation at the time of the neuraxial approach was 4 centimeters (IQR 4-6) and the epidural technique was the most frequently used – 92.9 % (n = 210). The mean postpartum surveillance was 20 hours (IQR 15-27). \u0000Conclusions: Half of the patients included received early analgesia and around fifty percent of them took longer than expected in completing delivery. The postpartum surveillance time was consistent with the provisions of the Ministry of Health and with the current trend of a short postpartum surveillance aimed at early hospital discharge and the benefits thereof.","PeriodicalId":36529,"journal":{"name":"Colombian Journal of Anesthesiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42962770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intravenous lidocaine in cancer-related neuropathic pain: case series 静脉注射利多卡因治疗癌症相关神经性疼痛:病例系列
Q3 Medicine Pub Date : 2021-09-20 DOI: 10.5554/22562087.E1004
Danny Steven Castiblanco-Delgado, Daniela Seija-Butnaru, Bilena Margarita Molina-Arteta
Introduction: Administering systemic lidocaine has been shown to deliver effective analgesia for both cancer-related and non-cancer pain. Adverse effects and toxicity are rare with controlled administration. Objective: To report the results obtained after the indication to manage with IV lidocaine infusion to control neuropathic pain flares in 9 cancer patients. Methodology: Observational, descriptive, case series-type study. A search was conducted in the files of the Pain and Palliative Care Service of the National Cancer Institute - Instituto Nacional de Cancerología - in Bogotá. Patients over 18 years old diagnosed with cancer, who experienced high intensity neuropathic pain and with the cognitive ability to rate their pain in a numerical analogue scale (NAS), without any absolute contraindications for the use of IV lidocaine were included; patients were assessed between September 27 and November 21, 2019. Results: 9 patients experiencing a pain flare-up which was characterized as neuropathic were registered, of which 89 % had some improvement following the administration of an initial lidocaine bolus. After one hour, 60 % reported over 40% improvement in the initial NAS. After 24 hours all patients had experienced some improvement, with a reduction of 46% in the pain scale as compared to the baseline. Conclusions: In this series of cases, the intravenous infusion of lidocaine as an option for the management of neuropathic pain flares seems to reduce pain intensity following the initial bolus administration.
简介:系统给予利多卡因已被证明提供有效的镇痛癌症相关和非癌症疼痛。在控制用药的情况下,不良反应和毒性是罕见的。目的:报告9例肿瘤患者静脉输注利多卡因控制神经性疼痛发作后的适应证。方法:观察性、描述性、病例系列研究。在波哥大国立癌症研究所(Instituto Nacional de Cancerología)疼痛和姑息治疗服务中心的档案中进行了搜索。患者年龄超过18岁,诊断为癌症,经历高强度神经性疼痛,有认知能力在数值模拟量表(NAS)中评估他们的疼痛,没有使用静脉注射利多卡因的绝对禁忌症;在2019年9月27日至11月21日期间对患者进行评估。结果:9例患者经历了以神经性疾病为特征的疼痛发作,其中89%的患者在给予初始利多卡因后有所改善。一小时后,60%的患者报告初始NAS改善超过40%。24小时后,所有患者都有一定的改善,与基线相比,疼痛程度降低了46%。结论:在这一系列病例中,静脉输注利多卡因作为治疗神经性疼痛发作的一种选择,似乎可以在最初的大剂量给药后减轻疼痛强度。
{"title":"Intravenous lidocaine in cancer-related neuropathic pain: case series","authors":"Danny Steven Castiblanco-Delgado, Daniela Seija-Butnaru, Bilena Margarita Molina-Arteta","doi":"10.5554/22562087.E1004","DOIUrl":"https://doi.org/10.5554/22562087.E1004","url":null,"abstract":"Introduction: Administering systemic lidocaine has been shown to deliver effective analgesia for both cancer-related and non-cancer pain. Adverse effects and toxicity are rare with controlled administration. \u0000Objective: To report the results obtained after the indication to manage with IV lidocaine infusion to control neuropathic pain flares in 9 cancer patients. \u0000Methodology: Observational, descriptive, case series-type study. A search was conducted in the files of the Pain and Palliative Care Service of the National Cancer Institute - Instituto Nacional de Cancerología - in Bogotá. Patients over 18 years old diagnosed with cancer, who experienced high intensity neuropathic pain and with the cognitive ability to rate their pain in a numerical analogue scale (NAS), without any absolute contraindications for the use of IV lidocaine were included; patients were assessed between September 27 and November 21, 2019. \u0000Results: 9 patients experiencing a pain flare-up which was characterized as neuropathic were registered, of which 89 % had some improvement following the administration of an initial lidocaine bolus. After one hour, 60 % reported over 40% improvement in the initial NAS. After 24 hours all patients had experienced some improvement, with a reduction of 46% in the pain scale as compared to the baseline. \u0000Conclusions: In this series of cases, the intravenous infusion of lidocaine as an option for the management of neuropathic pain flares seems to reduce pain intensity following the initial bolus administration.","PeriodicalId":36529,"journal":{"name":"Colombian Journal of Anesthesiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47745987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Iatrogenic tracheal wall injury 医源性气管壁损伤
Q3 Medicine Pub Date : 2021-09-10 DOI: 10.5554/22562087.e1003
S. Khanna, Roshni Sreedharan, Carlos Trombettaa
{"title":"Iatrogenic tracheal wall injury","authors":"S. Khanna, Roshni Sreedharan, Carlos Trombettaa","doi":"10.5554/22562087.e1003","DOIUrl":"https://doi.org/10.5554/22562087.e1003","url":null,"abstract":"","PeriodicalId":36529,"journal":{"name":"Colombian Journal of Anesthesiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45065395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Robotic-assisted laparoscopic partial nephrectomy. Retrospective descriptive study over a 10-year period. Anesthetic experience 机器人辅助腹腔镜肾部分切除术。为期10年的回顾性描述性研究。麻醉经验
Q3 Medicine Pub Date : 2021-09-09 DOI: 10.5554/22562087.E1001
Ana Pérez, A. López, Borja Mugabure Bujedo, Berta Castellano Paulis, Manuel Azcona Andueza, Edurne Lodoso Ochoa, Nuria González Jorrin
Introduction: Robot-assisted laparoscopic surgery is currently the surgical treatment of choice for small renal masses. Objective: Reviewing the anesthetic management and perioperative morbidity of patients undergoing robotic-assisted laparoscopic partial nephrectomy (RALPN) from 2009 to 2019 at Hospital Universitario Donostia. Material and methods: Retrospective, descriptive, observational study involving 343 patients. Results: 95 % of the patients were ASA II-III. Transient renal artery clamping was performed in 91 %, with a mean ischemia time of 17.79 minutes. The mean duration of the procedure under balanced general anesthesia was 184 min. Standard monitoring was performed along with invasive arterial pressure monitoring (IAP), central venous catheter (CVC) and EV1000 platform (Edwards®) for complex patients. Complications were recorded in 40 patients (11.67 %). Patients under anti-aggregation therapy experienced more bleeding than non-anti-aggregation patients (p 0.04) but did not require more transfusions. Patients with a higher anesthetic risk did not experience more complications. No statistically significant association was found between worsening renal function and the occurrence of intraoperative complications. 21 patients (6 %) were readmitted due to complications; the most frequent complication was renal artery pseudoaneurysm that required endovascular embolization. Conclusions: It should be highlighted that after ten years of experience with this technique, the patients with a higher anesthetic risk have not experienced serious perioperative complications. RALPN is a safe technique that demands a careful anesthetic support. A robot-assisted approach alone is not a guarantee for success without strong teamwork.
简介:机器人辅助腹腔镜手术是目前治疗肾脏小肿块的首选手术。目的:回顾2009年至2019年在Donostia大学医院接受机器人辅助腹腔镜部分肾切除术(RALPN)的患者的麻醉管理和围手术期发病率。材料和方法:回顾性、描述性、观察性研究,涉及343名患者。结果:95%的患者ASA为Ⅱ-Ⅲ级。91%的患者进行了短暂性肾动脉阻断,平均缺血时间为17.79分钟。在平衡全身麻醉下,手术的平均持续时间为184分钟。对复杂患者进行标准监测以及有创动脉压监测(IAP)、中心静脉导管(CVC)和EV1000平台(Edwards®)。40名患者(11.67%)出现并发症。接受抗聚集治疗的患者比未接受抗聚集疗法的患者出血更多(p 0.04),但不需要更多的输血。麻醉风险较高的患者没有出现更多并发症。肾功能恶化与术中并发症的发生之间没有统计学意义的相关性。21例(6%)患者因并发症再次入院;最常见的并发症是需要血管内栓塞的肾动脉假性动脉瘤。结论:值得强调的是,在使用该技术十年后,麻醉风险较高的患者没有出现严重的围手术期并发症。RALPN是一种安全的技术,需要仔细的麻醉支持。如果没有强有力的团队合作,仅靠机器人辅助的方法并不能保证成功。
{"title":"Robotic-assisted laparoscopic partial nephrectomy. Retrospective descriptive study over a 10-year period. Anesthetic experience","authors":"Ana Pérez, A. López, Borja Mugabure Bujedo, Berta Castellano Paulis, Manuel Azcona Andueza, Edurne Lodoso Ochoa, Nuria González Jorrin","doi":"10.5554/22562087.E1001","DOIUrl":"https://doi.org/10.5554/22562087.E1001","url":null,"abstract":"Introduction: Robot-assisted laparoscopic surgery is currently the surgical treatment of choice for small renal masses. \u0000Objective: Reviewing the anesthetic management and perioperative morbidity of patients undergoing robotic-assisted laparoscopic partial nephrectomy (RALPN) from 2009 to 2019 at Hospital Universitario Donostia. \u0000Material and methods: Retrospective, descriptive, observational study involving 343 patients. \u0000Results: 95 % of the patients were ASA II-III. Transient renal artery clamping was performed in 91 %, with a mean ischemia time of 17.79 minutes. The mean duration of the procedure under balanced general anesthesia was 184 min. Standard monitoring was performed along with invasive arterial pressure monitoring (IAP), central venous catheter (CVC) and EV1000 platform (Edwards®) for complex patients. Complications were recorded in 40 patients (11.67 %). Patients under anti-aggregation therapy experienced more bleeding than non-anti-aggregation patients (p 0.04) but did not require more transfusions. Patients with a higher anesthetic risk did not experience more complications. No statistically significant association was found between worsening renal function and the occurrence of intraoperative complications. 21 patients (6 %) were readmitted due to complications; the most frequent complication was renal artery pseudoaneurysm that required endovascular embolization. \u0000Conclusions: It should be highlighted that after ten years of experience with this technique, the patients with a higher anesthetic risk have not experienced serious perioperative complications. RALPN is a safe technique that demands a careful anesthetic support. A robot-assisted approach alone is not a guarantee for success without strong teamwork.","PeriodicalId":36529,"journal":{"name":"Colombian Journal of Anesthesiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42680990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Inverted P waves: harmless or harbinger of doom? 倒P波:无害还是厄运的预兆?
Q3 Medicine Pub Date : 2021-09-09 DOI: 10.5554/22562087.E1002
S. Khanna, Roshni Sreedharan, Carlos Trombettaa, S. Bustamante
P-waves represent atrial depolarization and appear upright in electrocardiographic leads I, II and V3-6, when they originate from the sinoatrial-node. New onset inverted P-waves, may result from benign or potentially life-threatening conditions. Anesthesiologists often have to decide if further work up is necessary in such circumstances, especially in symptomatic patients. We present two examples. Image A, an electrocardiogram from a patient who developed nausea while recovering in the post-anesthesia-care-unit after undergoing an uneventful cystoscopy, demonstrates inverted P-waves in lead I (red-arrows) and upright P-waves in lead V6 (bluearrows). As P-wave polarity should be similar in leads I and V6, the inconsistency in Image-A suggests reversal of left-arm and rightarm electrode positions.(1) Correct electrode placement rectified P-wave inversion and ondansetron administration ameliorated nausea. Image B demonstrates prominent inverted P-waves in inferiorleads II, III, aVF and precordial-leads V3-6 (red-arrows). This suggests retrograde atrial depolarization and in conjunction with a heartrate <70 beats/min, this pattern represents an atrioventricularjunctional-rhythm. Atrioventricular-junctional-rhythm may be a manifestation of sinus-node-dysfunction, myocardial-infarction, or digoxin-toxicity.(2) The electrocardiogram presented in Image B is from a patient who endorsed feeling nauseated in the postanesthesia-care-unit after undergoing an endoscopy under propofol-anesthesia. This patient accidentally continued his oral digoxin therapy while completing a clarithromycin-based Helicobacter-Pylori eradication regimen. Clarithromycin-induced inhibition of P-glycoprotein, an efflux pump that influences digoxin pharmacokinetics, results in increased gut absorption and decreased renal excretion of digoxin. This drug interaction can potentially precipitate digoxin-toxicity. As patients often present with non-specific symptoms such as nausea, abdominal pain, confusion, headache or dizziness, diagnosis of digoxin-toxicity necessitates a high index of suspicion. Electrocardiographic manifestations include severe bradyarrythmias and ventricular tachyarrhyhtmias. Although digoxin serum levels do not correlate with severity of toxicity, they help corroborate the diagnosis. In addition to atropine administration and institution of inotropic support, symptomatic and hemodynamically unstable digoxin-induced Received: 10 June, 2021 ▶ Accepted: 19 June, 2021 ▶ Online first: 9 September, 2021
P波代表心房去极化,当它们起源于窦房结时,在心电图导联I、II和V3-6中垂直出现。新发的反向P波可能是良性或潜在危及生命的情况造成的。麻醉师通常必须决定在这种情况下是否有必要进行进一步的检查,尤其是对有症状的患者。我们举两个例子。图像A是一名患者的心电图,该患者在麻醉后护理室接受了平静的膀胱镜检查后恢复时出现恶心,显示I导联出现倒置P波(红色箭头),V6导联出现直立P波(蓝色箭头)。由于导联I和V6中的P波极性应该相似,图像A中的不一致性表明左臂和右臂电极位置相反。(1) 正确的电极放置纠正了P波倒置和昂丹司琼给药改善了恶心。图像B显示下导联II、III、aVF和心前导联V3-6(红色箭头)出现明显的倒置P波。这表明心房逆行去极化,结合心率<70次/分,这种模式代表房室交界节律。房室交界性心律可能是窦房结功能障碍、心肌梗死或地高辛毒性的表现。(2) 图B中的心电图来自一名患者,该患者在丙泊酚麻醉下接受内窥镜检查后,在麻醉后护理室感到恶心。这位患者在完成基于克拉霉素的幽门螺杆菌根除方案时,意外地继续了他的口服地高辛治疗。克拉霉素诱导的P-糖蛋白(一种影响地高辛药代动力学的外排泵)的抑制导致地高辛的肠道吸收增加和肾脏排泄减少。这种药物相互作用可能导致地高辛中毒。由于患者经常出现非特异性症状,如恶心、腹痛、意识模糊、头痛或头晕,因此诊断地高辛毒性需要高度怀疑。心电图表现包括严重的缓慢性心律失常和室性心动过速。尽管地高辛血清水平与毒性的严重程度无关,但它们有助于证实诊断。除了阿托品给药和肌力支持机构外,症状和血液动力学不稳定的地高辛诱导接受时间:2021年6月10日▶ 接受日期:2021年6月19日▶ 首次在线:2021年9月9日
{"title":"Inverted P waves: harmless or harbinger of doom?","authors":"S. Khanna, Roshni Sreedharan, Carlos Trombettaa, S. Bustamante","doi":"10.5554/22562087.E1002","DOIUrl":"https://doi.org/10.5554/22562087.E1002","url":null,"abstract":"P-waves represent atrial depolarization and appear upright in electrocardiographic leads I, II and V3-6, when they originate from the sinoatrial-node. New onset inverted P-waves, may result from benign or potentially life-threatening conditions. Anesthesiologists often have to decide if further work up is necessary in such circumstances, especially in symptomatic patients. We present two examples. Image A, an electrocardiogram from a patient who developed nausea while recovering in the post-anesthesia-care-unit after undergoing an uneventful cystoscopy, demonstrates inverted P-waves in lead I (red-arrows) and upright P-waves in lead V6 (bluearrows). As P-wave polarity should be similar in leads I and V6, the inconsistency in Image-A suggests reversal of left-arm and rightarm electrode positions.(1) Correct electrode placement rectified P-wave inversion and ondansetron administration ameliorated nausea. Image B demonstrates prominent inverted P-waves in inferiorleads II, III, aVF and precordial-leads V3-6 (red-arrows). This suggests retrograde atrial depolarization and in conjunction with a heartrate <70 beats/min, this pattern represents an atrioventricularjunctional-rhythm. Atrioventricular-junctional-rhythm may be a manifestation of sinus-node-dysfunction, myocardial-infarction, or digoxin-toxicity.(2) The electrocardiogram presented in Image B is from a patient who endorsed feeling nauseated in the postanesthesia-care-unit after undergoing an endoscopy under propofol-anesthesia. This patient accidentally continued his oral digoxin therapy while completing a clarithromycin-based Helicobacter-Pylori eradication regimen. Clarithromycin-induced inhibition of P-glycoprotein, an efflux pump that influences digoxin pharmacokinetics, results in increased gut absorption and decreased renal excretion of digoxin. This drug interaction can potentially precipitate digoxin-toxicity. As patients often present with non-specific symptoms such as nausea, abdominal pain, confusion, headache or dizziness, diagnosis of digoxin-toxicity necessitates a high index of suspicion. Electrocardiographic manifestations include severe bradyarrythmias and ventricular tachyarrhyhtmias. Although digoxin serum levels do not correlate with severity of toxicity, they help corroborate the diagnosis. In addition to atropine administration and institution of inotropic support, symptomatic and hemodynamically unstable digoxin-induced Received: 10 June, 2021 ▶ Accepted: 19 June, 2021 ▶ Online first: 9 September, 2021","PeriodicalId":36529,"journal":{"name":"Colombian Journal of Anesthesiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48491291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Use of MeNTS, Frailty and Symptom Scales for selecting surgical patients during the SARS-CoV-2 pandemic: A retrospective study 在SARS-CoV-2大流行期间使用MeNTS、虚弱和症状量表选择手术患者:一项回顾性研究
Q3 Medicine Pub Date : 2021-09-02 DOI: 10.5554/22562087.e999
L. A. Tafur Betancourt, Adriana Sofía Rosero Cundar, Sergio Andrés Remolina Granados, Marcela Arévalo, María del Mar Millán G., Eduardo Lema Flórez, Andrés Zorrilla Vacca, Víctor Hernán Ruiz Holguín, Catalina Ceballos, Jaime Quintero Soto
Introduction: The SARS-CoV-2 pandemic has led to the cancellation of non-emergent surgeries in order to optimize the use of resources. Once the elective medical services are restored, a technical and ethical strategy becomes critical to select candidate patients for elective surgery. Objective: To describe the results from the implementation of MeNTS (Medically Necessary Time-sensitive Procedures), FI-CGA, and survey on COVID-19 symptoms Scales, as methods for the selection of patients who were candidates for elective surgery during the SARS-CoV-2 pandemic, in a third level institution in Cali, Colombia. Methodology: The databases of the results on the administration of MeNTS, frailty index (FI-CGA) and COVID 19 symptoms scales in patients who were candidates for elective surgery in a third level clinic in Cali city, between March 1st and August 31st, 2020 were reviewed. Results: A total of 1,044 patients were included, of which 647 (62.0 %) were females, with a mean age of 52 years (interquartile range [IQR] 38-62). 98 % of the patients were asymptomatic, the overall median score for MeNTS was 48 (IQR 44-52) and the average for FI-CGA was 0.0 (standard deviation 0.1). Conclusions: MeNTS, FI-CGA and the Symptoms Survey are easily accessible scales amidst the pandemic and are helpful to select patients with intermediate and low risk of perioperative morbidity in elective surgery during the SARS-CoV-2 pandemic. Further studies are required to confirm these findings and to clarify the potential of these tools in the selection of patients that meet the criteria to be identified as high risk.
引言:严重急性呼吸系统综合征冠状病毒2型疫情导致取消了非紧急手术,以优化资源使用。一旦恢复了选择性医疗服务,选择选择性手术的候选患者的技术和道德策略就变得至关重要。目的:描述MeNTS(医学必要时间敏感程序)、FI-CGA和新冠肺炎症状量表调查的实施结果,作为选择SARS-CoV-2大流行期间择期手术患者的方法,在哥伦比亚卡利的一家三级机构进行。方法:回顾了2020年3月1日至8月31日期间卡利市一家三级诊所择期手术候选患者的MeNTS、虚弱指数(FI-CGA)和COVID 19症状量表给药结果数据库。结果:共纳入1044名患者,其中647名(62.0%)为女性,平均年龄52岁(四分位间距[IQR]38-62)。MeNTS的总中位评分为48(IQR 44-52),FI-CGA的平均值为0.0(标准差0.1),FI-CGA和症状调查是疫情期间容易获得的量表,有助于在严重急性呼吸系统综合征冠状病毒2型疫情期间选择围手术期发病率中等和低风险的患者。需要进一步的研究来证实这些发现,并阐明这些工具在选择符合高风险标准的患者方面的潜力。
{"title":"Use of MeNTS, Frailty and Symptom Scales for selecting surgical patients during the SARS-CoV-2 pandemic: A retrospective study","authors":"L. A. Tafur Betancourt, Adriana Sofía Rosero Cundar, Sergio Andrés Remolina Granados, Marcela Arévalo, María del Mar Millán G., Eduardo Lema Flórez, Andrés Zorrilla Vacca, Víctor Hernán Ruiz Holguín, Catalina Ceballos, Jaime Quintero Soto","doi":"10.5554/22562087.e999","DOIUrl":"https://doi.org/10.5554/22562087.e999","url":null,"abstract":"Introduction: The SARS-CoV-2 pandemic has led to the cancellation of non-emergent surgeries in order to optimize the use of resources. Once the elective medical services are restored, a technical and ethical strategy becomes critical to select candidate patients for elective surgery. \u0000Objective: To describe the results from the implementation of MeNTS (Medically Necessary Time-sensitive Procedures), FI-CGA, and survey on COVID-19 symptoms Scales, as methods for the selection of patients who were candidates for elective surgery during the SARS-CoV-2 pandemic, in a third level institution in Cali, Colombia. \u0000Methodology: The databases of the results on the administration of MeNTS, frailty index (FI-CGA) and COVID 19 symptoms scales in patients who were candidates for elective surgery in a third level clinic in Cali city, between March 1st and August 31st, 2020 were reviewed. \u0000Results: A total of 1,044 patients were included, of which 647 (62.0 %) were females, with a mean age of 52 years (interquartile range [IQR] 38-62). 98 % of the patients were asymptomatic, the overall median score for MeNTS was 48 (IQR 44-52) and the average for FI-CGA was 0.0 (standard deviation 0.1). \u0000Conclusions: MeNTS, FI-CGA and the Symptoms Survey are easily accessible scales amidst the pandemic and are helpful to select patients with intermediate and low risk of perioperative morbidity in elective surgery during the SARS-CoV-2 pandemic. Further studies are required to confirm these findings and to clarify the potential of these tools in the selection of patients that meet the criteria to be identified as high risk.","PeriodicalId":36529,"journal":{"name":"Colombian Journal of Anesthesiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43380231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pain prevalence in infants and preschool children in a Colombian hospital 哥伦比亚一家医院婴儿和学龄前儿童的疼痛患病率
Q3 Medicine Pub Date : 2021-09-02 DOI: 10.5554/22562087.e1000
José Manuel Quintero-Castellanos, Ángela Hernández, Tania Parra
Introduction: The pain prevalence in hospitalized infants and preschool children has not been accurately identified in high-income countries, and in low and medium-income countries it has not been extensively studied. The assessment instruments are limited. Objective: To describe the prevalence and management of pain in infants and preschool children during the first 24 hours of hospitalization in a third level institution in Colombia, using the CRIES scale. Methods: An observational study was conducted during the first 24 hours of hospitalization. Demographic information was recorded, pain was assessed at admission, after 4, and 24 hours using the CRIES scale. Pharmacological therapy was also documented. Results: 250 children between one month and 5 years old were studied. The pain prevalence at admission was 12 %. The pain prevalence per subgroups was higher among the surgical patients, as compared to the clinical patients (35.9 % vs. 7.6 %). The pharmacological analysis revealed that 70.8 % of patients received treatment; the most widely used medications were oral acetaminophen and intravenous dipyrone. Conclusions: Pain prevalence was lower than the levels described for the general pediatric population. This result may be due to the sensitivity of the CRIES instrument, or to a particular pain behavior. Further studies are needed to identify the sensitivity of the assessment instruments in early life and to accurately investigate any associated phenomena.
引言:高收入国家尚未准确确定住院婴儿和学龄前儿童的疼痛患病率,中低收入国家也未对此进行广泛研究。评估工具是有限的。目的:使用CRIES量表描述哥伦比亚三级机构婴儿和学龄前儿童住院前24小时的疼痛发生率和管理情况。方法:在住院的前24小时内进行一项观察性研究。记录人口统计学信息,在入院时、4小时后和24小时后使用CRIES量表评估疼痛。药物治疗也有文献记载。结果:对250名1个月至5岁的儿童进行了研究。入院时疼痛发生率为12%。与临床患者相比,外科患者的每个亚组的疼痛发生率更高(35.9%对7.6%)。药理学分析显示,70.8%的患者接受了治疗;最广泛使用的药物是口服对乙酰氨基酚和静脉注射双嘧酮。结论:疼痛发生率低于一般儿科人群的描述水平。这种结果可能是由于CRIES仪器的敏感性,或者是由于特定的疼痛行为。需要进一步研究,以确定评估工具在早期的敏感性,并准确调查任何相关现象。
{"title":"Pain prevalence in infants and preschool children in a Colombian hospital","authors":"José Manuel Quintero-Castellanos, Ángela Hernández, Tania Parra","doi":"10.5554/22562087.e1000","DOIUrl":"https://doi.org/10.5554/22562087.e1000","url":null,"abstract":"Introduction: The pain prevalence in hospitalized infants and preschool children has not been accurately identified in high-income countries, and in low and medium-income countries it has not been extensively studied. The assessment instruments are limited. \u0000Objective: To describe the prevalence and management of pain in infants and preschool children during the first 24 hours of hospitalization in a third level institution in Colombia, using the CRIES scale. \u0000Methods: An observational study was conducted during the first 24 hours of hospitalization. Demographic information was recorded, pain was assessed at admission, after 4, and 24 hours using the CRIES scale. Pharmacological therapy was also documented. \u0000Results: 250 children between one month and 5 years old were studied. The pain prevalence at admission was 12 %. The pain prevalence per subgroups was higher among the surgical patients, as compared to the clinical patients (35.9 % vs. 7.6 %). The pharmacological analysis revealed that 70.8 % of patients received treatment; the most widely used medications were oral acetaminophen and intravenous dipyrone. \u0000Conclusions: Pain prevalence was lower than the levels described for the general pediatric population. This result may be due to the sensitivity of the CRIES instrument, or to a particular pain behavior. Further studies are needed to identify the sensitivity of the assessment instruments in early life and to accurately investigate any associated phenomena.","PeriodicalId":36529,"journal":{"name":"Colombian Journal of Anesthesiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46042652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Colombian Journal of Anesthesiology
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1