Pub Date : 2022-02-09DOI: 10.16931/1995-5464.2022-1-33-39
B. Medvedeva, A. Lukianchenko, V. Breder
The article reviews the key approaches to the use of modified response evaluation criteria in solid tumors (mRECIST) in patients with hepatocellular carcinoma and discusses its main strengths and features. According to the evaluation by mRECIST, complete response is defined as the disappearance of any intratumoral arterial enhancement in all target lesions. A partial response is defined as 30% decrease in the sum of the longest diameters of viable tumor target lesions compared with its baseline sum. Disease progression signifies a ≥20% increase in the sum of the longest diameters of viable tumor target lesions compared with nadir. Stable disease is defined as neither partial response nor progression.
{"title":"Features of modified response evaluation criteria use in solid tumors in patients with hepatocellular carcinoma","authors":"B. Medvedeva, A. Lukianchenko, V. Breder","doi":"10.16931/1995-5464.2022-1-33-39","DOIUrl":"https://doi.org/10.16931/1995-5464.2022-1-33-39","url":null,"abstract":"The article reviews the key approaches to the use of modified response evaluation criteria in solid tumors (mRECIST) in patients with hepatocellular carcinoma and discusses its main strengths and features. According to the evaluation by mRECIST, complete response is defined as the disappearance of any intratumoral arterial enhancement in all target lesions. A partial response is defined as 30% decrease in the sum of the longest diameters of viable tumor target lesions compared with its baseline sum. Disease progression signifies a ≥20% increase in the sum of the longest diameters of viable tumor target lesions compared with nadir. Stable disease is defined as neither partial response nor progression.","PeriodicalId":36549,"journal":{"name":"Annals of HPB Surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46018999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-02-09DOI: 10.16931/1995-5464.2022-1-87-93
G. V. Manukyan, R. Musin, V. M. Lebezev, S. B. Zhigalova, E. Kitsenko, D. Burenchev, V. Cherkasov, S. Rizaeva
This study demonstrates a successful clinical outcome in a female patient with severe refractory ascites associated with a complex combined form of extrahepatic portal hypertension. The study emphasizes the need and particular importance of comprehensive diagnostics and assessment of the angioarchitectonics in the portal vein system, thorough study of the porto–hepatic circulation and central hemodynamics, as well as of other major homeokinesis disorders. Understanding the pathogenesis of the disease allows for the development of a therapeutic plan with a strictly personalized approach toward the selection and staging of various surgical interventions.
{"title":"Refractory ascites of complex genesis in patients with a severe combined form of extrahepatic portal hypertension","authors":"G. V. Manukyan, R. Musin, V. M. Lebezev, S. B. Zhigalova, E. Kitsenko, D. Burenchev, V. Cherkasov, S. Rizaeva","doi":"10.16931/1995-5464.2022-1-87-93","DOIUrl":"https://doi.org/10.16931/1995-5464.2022-1-87-93","url":null,"abstract":"This study demonstrates a successful clinical outcome in a female patient with severe refractory ascites associated with a complex combined form of extrahepatic portal hypertension. The study emphasizes the need and particular importance of comprehensive diagnostics and assessment of the angioarchitectonics in the portal vein system, thorough study of the porto–hepatic circulation and central hemodynamics, as well as of other major homeokinesis disorders. Understanding the pathogenesis of the disease allows for the development of a therapeutic plan with a strictly personalized approach toward the selection and staging of various surgical interventions.","PeriodicalId":36549,"journal":{"name":"Annals of HPB Surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43308912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-02-09DOI: 10.16931/1995-5464.2022-1-48-55
A. Shabunin, V. Bedin, P. Drozdov, O. N. Levina, V. Tsurkan, O. S. Zhuravel
Aim: Analysis of the first experience of transjugular intrahepatic portosystemic shunting (TIPS) in patients with liver cirrhosis at a multidisciplinary hospital with a liver transplantation program.Materials and methods: The authors examined 206 patients with liver cirrhosis from July 2019 to June 2021, with 20 of them undergoing TIPS. The mean age of the patients was 47.59 ± 9.55 years (35–65 years). Dynamic follow-up was performed at 3, 6, 9, 12, and 18 months. As a part of the dynamic follow-up, the patients underwent laboratory tests, abdomen ultrasound examination, and computed tomography imaging enhanced by the intravenous use of contrasting agent, endoscopy, esophagogastroduodenoscopy, and encephalopathy assessment.Results: No in-hospital TIPS-associated mortality has been reported. Two patients died in the hospital at the 19th and 26th day following the surgery because of the progression of liver failure, the 6-week mortality rate was 10%. In one patient (5%), an intraoperative complication was reported, i.e., intra-abdominal hemorrhage secondary to the migration of the stent under the liver capsule. The length of hospital stay after surgery was 7.34 ± 1.89 days (5–26 days). Long-term outcomes were available for 17 patients. The duration of the dynamic follow-up was 13.23 ± 2.47 months (3–24 months) and 2 (11,7%) deaths were reported. One patient (5.8%) was diagnosed with a shunt thrombosis at 12 months after the surgery. Three patients underwent liver transplantation after TIPS. The current one-year survival rate is 90%.Conclusion: TIPS is a safe and effective procedure decreasing mortality and improving quality of life of patients awaiting cadaveric liver transplantation. TIPS should be widely implemented in multidisciplinary hospitals having liver transplant program.
目的:分析多学科医院肝移植项目肝硬化患者经颈静脉肝内门静脉系统分流术(TIPS)的首次经验。材料和方法:作者在2019年7月至2021年6月期间检查了206例肝硬化患者，其中20例接受了TIPS治疗。患者平均年龄为47.59±9.55岁(35 ~ 65岁)。分别在3、6、9、12和18个月进行动态随访。作为动态随访的一部分，患者接受了实验室检查、腹部超声检查、通过静脉使用造影剂增强的计算机断层扫描成像、内窥镜检查、食管胃十二指肠镜检查和脑病评估。结果:没有与tips相关的住院死亡率报告。2例患者术后第19天和第26天因肝功能衰竭进展在医院死亡，6周死亡率为10%。1例患者(5%)报告术中并发症，即肝包膜下支架迁移继发腹腔出血。术后住院时间为7.34±1.89 d (5 ~ 26 d)。17例患者获得了长期结果。动态随访时间为13.23±2.47个月(3 ~ 24个月)，死亡2例(11.7%)。1例患者(5.8%)在术后12个月被诊断为分流血栓形成。3例患者行肝移植手术。目前的一年生存率为90%。结论:TIPS是一种安全有效的方法，可降低尸体肝移植患者的死亡率，提高患者的生活质量。TIPS应广泛应用于有肝移植项目的多学科医院。
{"title":"First experience of transjugular intrahepatic portosystemic shunting at multidisciplinary hospital with a liver transplantation program","authors":"A. Shabunin, V. Bedin, P. Drozdov, O. N. Levina, V. Tsurkan, O. S. Zhuravel","doi":"10.16931/1995-5464.2022-1-48-55","DOIUrl":"https://doi.org/10.16931/1995-5464.2022-1-48-55","url":null,"abstract":"Aim: Analysis of the first experience of transjugular intrahepatic portosystemic shunting (TIPS) in patients with liver cirrhosis at a multidisciplinary hospital with a liver transplantation program.Materials and methods: The authors examined 206 patients with liver cirrhosis from July 2019 to June 2021, with 20 of them undergoing TIPS. The mean age of the patients was 47.59 ± 9.55 years (35–65 years). Dynamic follow-up was performed at 3, 6, 9, 12, and 18 months. As a part of the dynamic follow-up, the patients underwent laboratory tests, abdomen ultrasound examination, and computed tomography imaging enhanced by the intravenous use of contrasting agent, endoscopy, esophagogastroduodenoscopy, and encephalopathy assessment.Results: No in-hospital TIPS-associated mortality has been reported. Two patients died in the hospital at the 19th and 26th day following the surgery because of the progression of liver failure, the 6-week mortality rate was 10%. In one patient (5%), an intraoperative complication was reported, i.e., intra-abdominal hemorrhage secondary to the migration of the stent under the liver capsule. The length of hospital stay after surgery was 7.34 ± 1.89 days (5–26 days). Long-term outcomes were available for 17 patients. The duration of the dynamic follow-up was 13.23 ± 2.47 months (3–24 months) and 2 (11,7%) deaths were reported. One patient (5.8%) was diagnosed with a shunt thrombosis at 12 months after the surgery. Three patients underwent liver transplantation after TIPS. The current one-year survival rate is 90%.Conclusion: TIPS is a safe and effective procedure decreasing mortality and improving quality of life of patients awaiting cadaveric liver transplantation. TIPS should be widely implemented in multidisciplinary hospitals having liver transplant program.","PeriodicalId":36549,"journal":{"name":"Annals of HPB Surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46513000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-02-09DOI: 10.16931/1995-5464.2022-1-56-63
G. Aliyeva, G. Muslumov, B. Bayramov, N. Zeynalov, V. Behbudov
Aim: To investigate the association of the heme oxygenase-1 (HMOX1) gene polymorphism rs2071746 and chronic pancreatitis in the Azerbaijani population.Methods: From a period of 2014–2019, 70 patients with different types of chronic pancreatitis and 90 apparently healthy volunteers were observed. Of them, 55 subjects were consuming alcohol at least 3–4 times a week, with an average daily dose of >80 g/L, and 35 subjects were not consuming alcohol. The venous blood samples were collected from the control subjects and patients with pancreatitis; DNA was extracted and analyzed by polymerase chain reaction–restriction fragment length polymorphism.Results: The A allele in the homozygous form (A/A genotype) was found to be more common in patients with chronic pancreatitis (42.9%) than in the control group (16.6%). Thus, the A allele in the homozygous form (A/A genotype) may be associated with the development of chronic pancreatitis (odd ratio [OR] = 3.75; 95% confidence interval [CI] 1.81–7.77; p = 0.000). Furthermore, a statistical correlation between the A allele of the 495 A>T polymorphism (rs2071746) and an increased risk of the disease was observed. (p = 0.02, OR = 1.73; 95% CI 1.09–2.74). The heterozygous form of the A allele (A/T genotype; OR = 0.27; 95% CI = 0.13–0.56) and the T allele of the HMOX1 −495 A>T (rs2071746) polymorphism (OR = 0.53; 95% CI 0.32–0.89) reduced the risk of developing chronic alcoholic pancreatitis (p = 0.000 and p = 0.017, respectively).Conclusion: The identification of genetic association of the various types of chronic pancreatitis will encourage further research on HMOX1, drug development, or the use of hemin in clinical practice.
{"title":"Association between heme oxygenase-1 (HMOX1) gene polymorphism and chronic pancreatitis","authors":"G. Aliyeva, G. Muslumov, B. Bayramov, N. Zeynalov, V. Behbudov","doi":"10.16931/1995-5464.2022-1-56-63","DOIUrl":"https://doi.org/10.16931/1995-5464.2022-1-56-63","url":null,"abstract":"Aim: To investigate the association of the heme oxygenase-1 (HMOX1) gene polymorphism rs2071746 and chronic pancreatitis in the Azerbaijani population.Methods: From a period of 2014–2019, 70 patients with different types of chronic pancreatitis and 90 apparently healthy volunteers were observed. Of them, 55 subjects were consuming alcohol at least 3–4 times a week, with an average daily dose of >80 g/L, and 35 subjects were not consuming alcohol. The venous blood samples were collected from the control subjects and patients with pancreatitis; DNA was extracted and analyzed by polymerase chain reaction–restriction fragment length polymorphism.Results: The A allele in the homozygous form (A/A genotype) was found to be more common in patients with chronic pancreatitis (42.9%) than in the control group (16.6%). Thus, the A allele in the homozygous form (A/A genotype) may be associated with the development of chronic pancreatitis (odd ratio [OR] = 3.75; 95% confidence interval [CI] 1.81–7.77; p = 0.000). Furthermore, a statistical correlation between the A allele of the 495 A>T polymorphism (rs2071746) and an increased risk of the disease was observed. (p = 0.02, OR = 1.73; 95% CI 1.09–2.74). The heterozygous form of the A allele (A/T genotype; OR = 0.27; 95% CI = 0.13–0.56) and the T allele of the HMOX1 −495 A>T (rs2071746) polymorphism (OR = 0.53; 95% CI 0.32–0.89) reduced the risk of developing chronic alcoholic pancreatitis (p = 0.000 and p = 0.017, respectively).Conclusion: The identification of genetic association of the various types of chronic pancreatitis will encourage further research on HMOX1, drug development, or the use of hemin in clinical practice.","PeriodicalId":36549,"journal":{"name":"Annals of HPB Surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45322250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-02-09DOI: 10.16931/10.16931/1995-5464.2022-1-72-79
Российская Федерация, Минздрава России
The paper presents an analysis of the recent studies on the various aspects of surgical management of acute (excluding biliary) pancreatitis. It evaluates the suggestion of interventions in the sterile phase, which are limited to and include enzymatic peritonitis and abdominal compartment syndrome. Surgery is suggested when conservative treatment is ineffective, pain is present, which is associated with pancreatic fluid accumulation, there is a risk of the pancreatic fluid leaking into the abdominal cavity, or compression of the adjacent organs develops due to the disconnected pancre-atic duct syndrome. Infected necrosis is the main indication for surgical intervention in acute pancreatitis. The drainage is preferably delayed for at least 4 weeks following the onset of the disease, and is gradually performed (in a “step-up” manner). The choice of drainage technique is based on the necrosis localization, delimiting wall, surgeon’s expertise, and technical capabilities. Sequestrectomy can be performed starting from mini-invasive percutaneous drainage under endoscopic guidance, or using a covered metal stent. In the cases of early infection or advanced injury of retroperitoneal tissue, it is advisable to combine percutaneous and endoscopic methods, and use multiple transluminal gateway techniques with several draining tracts installed from single or multiple points of access.
{"title":"Surgical treatment of acute pancreatitis","authors":"Российская Федерация, Минздрава России","doi":"10.16931/10.16931/1995-5464.2022-1-72-79","DOIUrl":"https://doi.org/10.16931/10.16931/1995-5464.2022-1-72-79","url":null,"abstract":"The paper presents an analysis of the recent studies on the various aspects of surgical management of acute (excluding biliary) pancreatitis. It evaluates the suggestion of interventions in the sterile phase, which are limited to and include enzymatic peritonitis and abdominal compartment syndrome. Surgery is suggested when conservative treatment is ineffective, pain is present, which is associated with pancreatic fluid accumulation, there is a risk of the pancreatic fluid leaking into the abdominal cavity, or compression of the adjacent organs develops due to the disconnected pancre-atic duct syndrome. Infected necrosis is the main indication for surgical intervention in acute pancreatitis. The drainage is preferably delayed for at least 4 weeks following the onset of the disease, and is gradually performed (in a “step-up” manner). The choice of drainage technique is based on the necrosis localization, delimiting wall, surgeon’s expertise, and technical capabilities. Sequestrectomy can be performed starting from mini-invasive percutaneous drainage under endoscopic guidance, or using a covered metal stent. In the cases of early infection or advanced injury of retroperitoneal tissue, it is advisable to combine percutaneous and endoscopic methods, and use multiple transluminal gateway techniques with several draining tracts installed from single or multiple points of access.","PeriodicalId":36549,"journal":{"name":"Annals of HPB Surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46482862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-02-09DOI: 10.16931/1995-5464.2022-1-64-71
E. Zamanov, M. Efanov
This literature review highlights the recent advances in the prevention and prognosis of purulent-septic complications, post-resection liver failure, and other severe postoperative complications following the surgical treatment of hilar cholangiocarcinoma. The data obtained from the analysis of the recent scientific publications indicate the relevance of this problem. Research should be prioritized to formulate combined methods that can assess the risk of perioperative complications.
{"title":"Prediction and prevention of severe complications following radical surgical treatment of hilar cholangiocarcinoma","authors":"E. Zamanov, M. Efanov","doi":"10.16931/1995-5464.2022-1-64-71","DOIUrl":"https://doi.org/10.16931/1995-5464.2022-1-64-71","url":null,"abstract":"This literature review highlights the recent advances in the prevention and prognosis of purulent-septic complications, post-resection liver failure, and other severe postoperative complications following the surgical treatment of hilar cholangiocarcinoma. The data obtained from the analysis of the recent scientific publications indicate the relevance of this problem. Research should be prioritized to formulate combined methods that can assess the risk of perioperative complications.","PeriodicalId":36549,"journal":{"name":"Annals of HPB Surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47518115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-02-09DOI: 10.16931/1995-5464.2022-1-12-21
G. Karmazanovsky, L. Abuladze
Aim: To present the computed tomography and magnetic resonance imaging assessments of benign and malignant duodenal tumors, pancreatic head adenocarcinoma invading the duodenum, and duodenal dystrophy.Methods: We searched for scientific papers and clinical guidelines in the information and analytical databases PubMed and Google Scholar from the 2013–2021 period using the following search terms: duodenal neoplasms, adenocarcinoma, duodenum, duodenal neuroendocrine tumors, duodenal adenoma, gastrointestinal stromal tumor, cholangiocarcinoma, radiology, magnetic resonance imaging, computed tomography, pancreatic head cancer. Then, we examined the reference lists of all the identified studies to collate the papers that would meet the eligibility criteria.Results: We analyzed 1494 articles, 22 of which were included in our review. From the papers published within 1992–2021, 35 articles from the reference lists were additionally included. Based on the search results, several domains of articles were clustered; the articles from those domains were reviewed and evaluated that involved the abovementioned diagnostic features.Conclusion: The early diagnosis and selection of appropriate management methods remain extremely relevant for the treatment of duodenal tumors, and hence, require careful attention from diagnosticians and clinicians.
{"title":"Computer-assisted and magnetic resonance imaging assessment of tumors and tumor invasion of the duodenum","authors":"G. Karmazanovsky, L. Abuladze","doi":"10.16931/1995-5464.2022-1-12-21","DOIUrl":"https://doi.org/10.16931/1995-5464.2022-1-12-21","url":null,"abstract":"Aim: To present the computed tomography and magnetic resonance imaging assessments of benign and malignant duodenal tumors, pancreatic head adenocarcinoma invading the duodenum, and duodenal dystrophy.Methods: We searched for scientific papers and clinical guidelines in the information and analytical databases PubMed and Google Scholar from the 2013–2021 period using the following search terms: duodenal neoplasms, adenocarcinoma, duodenum, duodenal neuroendocrine tumors, duodenal adenoma, gastrointestinal stromal tumor, cholangiocarcinoma, radiology, magnetic resonance imaging, computed tomography, pancreatic head cancer. Then, we examined the reference lists of all the identified studies to collate the papers that would meet the eligibility criteria.Results: We analyzed 1494 articles, 22 of which were included in our review. From the papers published within 1992–2021, 35 articles from the reference lists were additionally included. Based on the search results, several domains of articles were clustered; the articles from those domains were reviewed and evaluated that involved the abovementioned diagnostic features.Conclusion: The early diagnosis and selection of appropriate management methods remain extremely relevant for the treatment of duodenal tumors, and hence, require careful attention from diagnosticians and clinicians.","PeriodicalId":36549,"journal":{"name":"Annals of HPB Surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49548701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-02-09DOI: 10.16931/1995-5464.2022-1-80-86
A. Dobrodeev, D. Kostromitsky, S. Afanasyev, A. Tarasova, A. Avgustinovich
Hepatic resection has become the treatment of choice for metastatic colorectal cancer, and this treatment technique increases the five-year survival of cancer patients up to 40–58%. More recently, the criteria for resectability have been revised and expanded to include any patient in whom all metastatic deposits can be removed with a negative surgical margin and with sufficient residual liver parenchyma. Currently, resectability is determined mostly by the minimum functional liver remnant volume. Under this new paradigm, the number of patients with potentially resectable oncological process can be increased. However, there are no widely accepted concepts and criteria for resectability, which further complicates the choice of treatment methods and directly affects the patients’ survival. The literature search for this review was performed using PubMed, Cochrane Library, Google Scholar, and eLibrary systems. We included publications that characterized the modern possibilities of liver surgery aimed at increasing resectability and improving cancer outcomes in patients with colorectal cancer liver metastases.
{"title":"Modern approaches to surgical treatment of patients with colorectal cancer liver metastases","authors":"A. Dobrodeev, D. Kostromitsky, S. Afanasyev, A. Tarasova, A. Avgustinovich","doi":"10.16931/1995-5464.2022-1-80-86","DOIUrl":"https://doi.org/10.16931/1995-5464.2022-1-80-86","url":null,"abstract":"Hepatic resection has become the treatment of choice for metastatic colorectal cancer, and this treatment technique increases the five-year survival of cancer patients up to 40–58%. More recently, the criteria for resectability have been revised and expanded to include any patient in whom all metastatic deposits can be removed with a negative surgical margin and with sufficient residual liver parenchyma. Currently, resectability is determined mostly by the minimum functional liver remnant volume. Under this new paradigm, the number of patients with potentially resectable oncological process can be increased. However, there are no widely accepted concepts and criteria for resectability, which further complicates the choice of treatment methods and directly affects the patients’ survival. The literature search for this review was performed using PubMed, Cochrane Library, Google Scholar, and eLibrary systems. We included publications that characterized the modern possibilities of liver surgery aimed at increasing resectability and improving cancer outcomes in patients with colorectal cancer liver metastases.","PeriodicalId":36549,"journal":{"name":"Annals of HPB Surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48915520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-02-09DOI: 10.16931/1995-5464.2022-1-94-100
I. P. Kirtanasov, A. Andreev, V. M. Durleshter, S. A. Gabriel’, L. G. Izmailova
The paper presents the clinical observations of the rare complication of hepatic hydatid disease: the rupture of hydatide cysts into the bile ducts. The complication causes obstruction of the bile ducts, obstructive jaundice, and cholangitis. The basic stages of diagnosis and the role of ultrasound in detecting the complications of hepatic hydatid disease have been highlighted in this paper. The minimally invasive percutaneous and endoscopic techniques under radiological guidance have been reviewed.
{"title":"Minimally invasive treatment of hepatic hydatid cysts complicated by the rupture into the biliary tract","authors":"I. P. Kirtanasov, A. Andreev, V. M. Durleshter, S. A. Gabriel’, L. G. Izmailova","doi":"10.16931/1995-5464.2022-1-94-100","DOIUrl":"https://doi.org/10.16931/1995-5464.2022-1-94-100","url":null,"abstract":"The paper presents the clinical observations of the rare complication of hepatic hydatid disease: the rupture of hydatide cysts into the bile ducts. The complication causes obstruction of the bile ducts, obstructive jaundice, and cholangitis. The basic stages of diagnosis and the role of ultrasound in detecting the complications of hepatic hydatid disease have been highlighted in this paper. The minimally invasive percutaneous and endoscopic techniques under radiological guidance have been reviewed.","PeriodicalId":36549,"journal":{"name":"Annals of HPB Surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44453551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-02-09DOI: 10.16931/1995-5464.2022-1-40-47
K. A. Zamyatina, M. Godzenko, G. G. Kаrmаzаnovsky, A. Revishvili
A study of the international literature on texture analysis was performed, and the reported data was compared to the findings of radiomics studies performed by the specialists of our institute. The relevant papers were searched using a combination of the following search terms: “radiomics”, “radiology”, “texture analysis”, “perspectives”, and “clinical implementation”. The search was limited to papers published in English within the last 5 years, which essentially focused on liver and pancreas disorders. Due to the publication of new data on a fairly daily basis, the topic has not lost its relevance. The vast majority of authors confirm that radiomics can be efficiently used during diagnosis, treatment planning, and patient monitoring. However, consensus on the implementation of radiomics has not been reached yet, thereby delaying its introduction into clinical practice. The data collected in our institution reports that the clinical application of texture analysis methods may be very promising.
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