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Wounds and wound infections. The prof. B.M. Kostyuchenok journal最新文献

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Post-release of the International Scientific and Practice Congress “Diabetes Mellitus, Its Complications and Surgical Infections” (November 19–21, 2019, Moscow, Russia) 国际科学与实践大会“糖尿病及其并发症和手术感染”发布后(2019年11月19-21日,俄罗斯莫斯科)
Pub Date : 2021-07-24 DOI: 10.25199/2408-9613-2020-7-3-6-13
Yu. S. Paskhalova
The article presents the chronology of the International Scientific and Practice Congress “Diabetes Mellitus, Its Complications and Surgical Infections” (November 19–21, 2019).
文章介绍了国际科学与实践大会“糖尿病及其并发症和手术感染”(2019年11月19-21日)的年表。
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引用次数: 0
Experience in the treatment of Fournier's gangrene in a hospital of the Far North 远北地区某医院治疗富尼耶坏疽的经验
Pub Date : 2021-07-23 DOI: 10.25199/2408-9613-2020-7-3-32-39
N. Bruklich, A. Orunbaeva, E. G. Nersesyan
The article presents several clinical observations about the experience of treating Fournier's gangrene in a hospital in the Far North.
本文介绍了一些临床观察的经验,治疗富尼耶坏疽在医院在遥远的北方。
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引用次数: 0
Anniversary of Leonid Aleksandrovich Blatun (March 29, 1941) 列昂尼德·亚历山德罗维奇·布拉通诞辰纪念日(1941年3月29日)
Pub Date : 2021-07-22 DOI: 10.25199/2408-9613-2021-8-1-6-11
Yu. S. Paskhalova
The article presents a brief biography of the senior researcher in wounds and wound infections department and clinical microbiologist of the Federal State Budgetary Institution “A. V. Vishnevsky National Medical Research Center of Surgery” Ministry of Health of Russia Leonid Aleksandrovich Blatun (03/29/1941) in honor of his 80th anniversary, of which 55 years passed within the walls of the A. V. Vishnevsky institute of surgery!
本文介绍了伤口和伤口感染部门的高级研究员和联邦国家预算机构“a”的临床微生物学家的简要传记。维什涅夫斯基国家外科医学研究中心”俄罗斯卫生部列昂尼德·亚历山德罗维奇·布拉顿(1941年3月29日)纪念他80周年,其中55年是在维什涅夫斯基外科研究所度过的!
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引用次数: 0
Influence of the combined method of air-plasma flows and NO-therapy on the blood system parameters in treatment of infectious wound complications in cardiac surgery 空气-血浆流联合no治疗对心脏手术感染性伤口并发症血液系统参数的影响
Pub Date : 2021-07-22 DOI: 10.25199/2408-9613-2021-8-1-30-41
M. Kuznetsov, G. Nasrashvili, D. Panfilov, R. S. Kozhanov, A. S. Pryakhin, V. Shipulin, B. Kozlov
Nitric oxide (NO) is a universal biological mediator that has a multifaceted effect on physiological and pathological processes in various organs and systems of the body. It is known that NO-therapy is a powerful stimulator of a positive effect on the course of the wound process, especially in complicated wounds.Objective: to evaluate the use of the combined effect of NO-containing air-plasma flows on the parameters of the blood system in the treatment of infectious wound complications in cardiac surgery patients.Materials and methods. A total of 60 patients were included in the study: 31 (52%) men and 29 (48%) women aged 29 to 79 years (mean 63.67 ± 7.6 years). All patients were divided into two groups: Group I – 30 patients who received treatment for sternomediastinitis using a combined exposure to air-plasma flow and exogenous nitric oxide; Group II – 30 patients who were treated for sternomediastinitis according to the clinical guidelines for the surgical treatment of patients with postoperative mediastinitis and osteomyelitis of the sternum and ribs.Results. The use of the combined effect of NO-containing air-plasma flows for the treatment of sternomediastinitis is accompanied by a decrease in the level of acute phase proteins already by 3 days, normalization of leukocytes and neutrophils by 10 days after the start of therapy, and prevents hyperaggregation and spontaneous aggregation of platelets.Conclusion. The use of the combined method of low-temperature plasma and exogenous nitrogen monoxide in the local treatment of infectious wound complications after cardiac surgery is justified and effective. No reliable confirmation of the cytotoxic effect of exogenous nitric oxide in the applied dosage on the elements of red blood was found in this study
一氧化氮(NO)是一种普遍的生物介质,对身体各器官和系统的生理和病理过程具有多方面的影响。众所周知,一氧化氮治疗是一种强大的刺激剂,对伤口过程的过程有积极的影响,特别是在复杂的伤口。目的:探讨含no空气-血浆联合流动对血液系统参数的影响在心脏手术患者感染性伤口并发症治疗中的应用。材料和方法。共纳入60例患者:男性31例(52%),女性29例(48%),年龄29 ~ 79岁(平均63.67±7.6岁)。所有患者分为两组:第一组- 30例接受胸骨纵隔炎联合暴露于空气-血浆流和外源性一氧化氮治疗;第二组:30例胸骨纵隔炎患者,按照术后纵隔炎合并胸骨及肋部骨髓炎的手术治疗临床指南进行治疗。使用含no的空气-血浆流联合作用治疗胸骨纵隔炎,可使急性期蛋白水平下降3天,白细胞和中性粒细胞在治疗开始后10天恢复正常,并可防止血小板的超聚集和自发聚集。低温血浆联合外源性一氧化氮局部治疗心脏手术后感染性伤口并发症是合理有效的。本研究未发现外源性一氧化氮在应用剂量下对红细胞元素的细胞毒性作用
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引用次数: 1
Ways to reduce the frequency of high amputations, post-amputation complications and mortality in diabetic foot syndrome 降低糖尿病足综合征高位截肢率、截肢后并发症及死亡率的方法
Pub Date : 2021-07-22 DOI: 10.25199/2408-9613-2021-8-1-12-23
V. M. Bensman, A. Baryshev, S. Pyatakov, K. G. Triandafilov, V. N. Ponomarev, V. V. Fedyushkin, D. Y. Sheremetyev, A. O. Sheremetyeva, A. Kiba
Despite the success in treatment, currently 30.0% of patients with diabetic foot syndrome (DFS) still undergo high amputations with a mortality rate of up to 54.0–68.0 %. The causes of high low limb amputations in 28.0 % of patients are infection, and in 46.0 % – arterial insufficiency in the stage of critical limb ischemia.Objective: to improve the results of patients treatment by reducing the number of high amputations of the lower extremities, reducing the occurrence of complications and deaths of the disease.Materials and methods. To study the results of treatment of patients with DFS, they were divided into two comparison groups and two main groups. From 1982 to 2019, the frequency of amputations, mainly at the hip level, was 71.0 % (177 amputations in 248 patients). These patients formed the first comparison group of observations. The second comparison group (1988–1994) included 58.3 % of patients in whom amputations were performed according to more stringent indications (157 amputations in 269 patients). The first main group of observations (1995–2013) included 9.9 % of patients with DFS who were amputated only for wet gangrene, incurable critical limb ischemia, and infection with a systemic inflammatory response (130 amputations out of 1312 patients). In ischemia with preserved blood flow through the deep artery of the thigh, amputation of the lower leg was performed in a sequential-two-flap method with removal of the soleus muscle. Amputations were completed with the imposition of drainage removable muscle-fascial sutures. The second main group (2014) consisted of 11.4 % of patients who underwent amputations only for sepsis or wet gangrene (124 amputations in 1083 patients). The difference between the second main group and the first was the division of the high amputation intervention into 2 stages.Results. Comparison of the treatment results in the main groups and in the comparison groups revealed a 6-fold decrease in the number of high amputations (from 64.6 to 10.69 %) and a significant improvement in the main quality indicators. This concerns a 6-fold decrease in mortality, which was a consequence of the introduction of a two-stage tactic for high amputation treatment of the most severe patients and the limitation of indications for amputation of the hip. Using of removable drainage muscle-fascial sutures decreased postoperative wound complications from 51.9 to 13.0 %, and the number of re-amputations decreased in 17th times.Conclusion. Amputation of the lower extremities for irreversible critical limb ischemia can be performed with a decrease in TcP02 of the stitched stump tissues to no more than 30 mm Hg. Preserving the knee joint improves the possibilities of prosthetics, which allows older diabetics to lead an active life. Methods of performing parallel- or sequential-two-flap high amputation improve the conditions for cutting out racquet-shaped wound flaps, which provides free displacement of the soft tissues of the stump connec
尽管治疗取得了成功,但目前仍有30.0%的糖尿病足综合征(DFS)患者接受高度截肢,死亡率高达54.0% ~ 68.0%。高下肢截肢的原因28.0%是感染,46.0%是危重肢体缺血期动脉功能不全。目的:通过减少下肢高位截肢次数,减少疾病并发症的发生和死亡,提高患者的治疗效果。材料和方法。为研究DFS患者的治疗效果,将患者分为两组对照组和两组主组。1982年至2019年,截肢发生率为71.0%(248例患者中177例截肢),主要发生在髋关节水平。这些患者组成了第一个观察对照组。第二组(1988-1994)包括58.3%的患者,他们根据更严格的指征进行截肢(269例患者中157例截肢)。第一组主要观察(1995-2013)包括9.9%仅因湿性坏疽、无法治愈的严重肢体缺血和全身炎症反应感染而截肢的DFS患者(1312例患者中有130例截肢)。在缺血的情况下,保留血流通过大腿深动脉,采用顺序双瓣法切除比目鱼肌,切除小腿。截肢手术采用引流可移动肌筋膜缝合线。第二组(2014年)包括11.4%仅因脓毒症或湿性坏疽接受截肢的患者(1083例患者中有124例截肢)。第二主组与第一主组的区别在于将高位截肢干预分为2个阶段。主要组和对照组的治疗结果比较显示,高位截肢率下降了6倍(从64.6%降至10.69%),主要质量指标有了显著改善。这与死亡率降低6倍有关,这是对最严重的患者采用两阶段高位截肢治疗策略和限制髋关节截肢指征的结果。采用可移动引流肌筋膜缝合线使术后创面并发症从51.9%减少到13.0%,再截肢次数减少17次。对于不可逆的严重肢体缺血的下肢截肢,可以将缝合的残肢组织的TcP02降低到不超过30毫米汞柱。保留膝关节可以提高假肢的可能性,使老年糖尿病患者能够过上积极的生活。平行或顺序双瓣高位截肢的方法改善了切割球拍状伤口皮瓣的条件,这提供了残肢软组织的自由位移,并通过可移动的引流缝线连接。
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引用次数: 0
Features of the course of Fournier’s gangrene in patients with diabetes mellitus 糖尿病患者富尼耶坏疽病程特点分析
Pub Date : 2021-07-22 DOI: 10.25199/2408-9613-2021-8-1-24-29
A. Imankulova, O. T. Kochorov, U. T. Naraliev
Fournier’s gangrene (FG) is a septic process accompanied by tissue necrosis of the scrotum, penis and perineum, as well as systemic inflammatory syndrome and endotoxicosis. FG is associated with long hospital stay and high mortality. In recent decades, there has been an increase in the incidence of this pathology, as evidenced by the indicators of the “database of the treated case” in Kyrgyzstan. This fact is associated with the growth of immunocompromised patients and, first of all, patients with diabetes mellitus. The result of treatment depends on the correct tactics, time and volume of emergency surgery. This article presents a 5-year experience of treating patients with FG against the background of diabetes mellitus in the department of purulent surgery of the National Hospital in Bishkek.
富尼耶坏疽(Fournier’s gangrene, FG)是一种脓毒症过程,伴有阴囊、阴茎和会阴组织坏死,以及全身性炎症综合征和内毒素中毒。FG与住院时间长和死亡率高有关。近几十年来,吉尔吉斯斯坦“治疗病例数据库”的指标证明,这种病理的发病率有所增加。这一事实与免疫功能低下患者的增长有关,首先是糖尿病患者。治疗的结果取决于正确的策略、时间和急诊手术的数量。本文介绍了在比什凯克国立医院化脓性外科治疗糖尿病背景下FG患者的5年经验。
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引用次数: 0
Post release International Scientific and Practice Conference “High low limb amputations in children and adult” 国际科学与实践会议“儿童与成人高下肢截肢”
Pub Date : 2020-12-08 DOI: 10.25199/2408-9613-2020-7-1-67-73
Yu. S. Paskhalova
The article presents the chronology of the International Scientific and Practice Conference “High low limb amputations in children and adult” (May 20–21, 2019).
文章介绍了“儿童和成人高下肢截肢”国际科学与实践会议(2019年5月20日至21日)的年表。
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引用次数: 0
The role of the angiosomaly-oriented endovascular revascularization method in the complex treatment of diabetic foot syndrome 血管体定向血管内血管重建术在糖尿病足综合征复杂治疗中的作用
Pub Date : 2020-12-08 DOI: 10.25199/2408-9613-2020-7-1-36-45
V. Petrova, G. Smirnov, M. N. Arzhelas
Objective: analyze the effectiveness of the angiosomal oriented endovascular revascularization method in the complex treatment of diabetic foot syndrome (DFS). Materials and methods. One of the most serious complications of diabetes mellitus is damage to the vessels of the lower extremities. In diabetic macroangiopathy, an extended lesion of medium-sized arteries occurs, which, coupled with an atherosclerotic lesion, often leads to the formation of arterial stenosis and occlusion. The leading method for correcting the patency of the great vessels today is endovascular balloon angioplasty. The study examined the feasibility of selective angiosomal revascularization of the lower extremities. The advantages of angiosomaly-oriented endovascular revascularization are a reduction in the duration of the intervention, a decrease in the volume of the injected contrast drug, and targeted restoration of blood flow in the arteries that feed the affected segment of the limb. The study included 49 patients with a neuroischemic form of DFS with hemodynamically significant stenosis and occlusion of the lower extremities arteries. Patients were divided into 2 groups. Patients of both groups underwent complex conservative treatment and performed operations on the lower extremities (from surgical debridement to below the knee amputation). Patients of the first group underwent angiosomaly oriented revascularization of the lower extremities. Patients from the second group underwent traditional endovascular revascularization. Results. After angiosomaly oriented revascularization, a complete restoration of the initial diameter of the vessel was achieved in 80.0 % of cases, the absence of residual stenosis – in 82.5 %, the absence of intimal dissection – in 95.0 % of cases. It was possible to achieve laminar blood flow in 90.0 % of cases. A reduction in the revascularization procedure by an average of 30 minutes and a decrease in the consumption of contrasting pharmaceuticals by an average of 100.0 ml are shown. Conclusion. When evaluating the results of complex treatment of patients after angiosomaly oriented revascularization, a decrease in the average hospital stay (11 and 13 days, respectively), a decrease in the average healing time of a wound defect by 1.25 times, a decrease in the average duration of ulcerative epithelization (9 and 13 days, respectively) and a decrease in the volume of surgical intervention and the number of high amputations during the year after angioplasty compared with patients who underwent endovascular revascularization according to the traditional method.
目的:分析血管小体定向血管内血管重建术在糖尿病足综合征(DFS)综合治疗中的效果。材料和方法。糖尿病最严重的并发症之一是下肢血管的损害。在糖尿病大血管病变中,中等动脉病变扩大,并伴有动脉粥样硬化病变,常导致动脉狭窄和闭塞的形成。目前矫正大血管通畅的主要方法是血管内球囊血管成形术。本研究探讨了选择性下肢血管体重建术的可行性。以血管躯体为导向的血管内血管重建术的优点是缩短了干预时间,减少了注射造影剂的体积,并有针对性地恢复了肢体受影响部分的动脉血流。该研究包括49例神经缺血性DFS患者,伴有血流动力学上明显的下肢动脉狭窄和闭塞。患者分为两组。两组患者均进行了复杂的保守治疗,并对下肢进行了手术(从手术清创到膝下截肢)。第一组患者行下肢血管成形术。第二组患者行传统血管内血管重建术。结果。在血管成形术后,80.0%的病例血管初始直径完全恢复,82.5%的病例没有残留狭窄,95.0%的病例没有内膜夹层。在90%的病例中有可能实现层流血流。血运重建过程平均减少30分钟,对比药物的消耗平均减少100.0毫升。结论。在评估血管成形术后患者的综合治疗结果时,平均住院时间减少(分别为11天和13天),伤口缺损平均愈合时间减少1.25倍,溃疡性上皮平均持续时间减少(9天和13天)。与传统方法行血管内重建术的患者相比,血管成形术后一年内的手术干预量和高位截肢数量均有所减少。
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引用次数: 0
The use of a vacuum aspiration system for the treatment of anterior abdominal wall purulent wounds after complicated abdominoplasty 应用真空抽吸系统治疗复杂腹部成形术后前腹壁脓性伤口
Pub Date : 2020-09-02 DOI: 10.25199/2408-9613-2019-6-3-44-49
M. R. Gafiullov, S. Suvorov, V. Orelkin, Yu. D. Orelkin
The article presents the experience of successful complex treatment of a 55-year-old patient with morbid obesity (BMI 66.3 kg / m2) who underwent excision of a skin-fat apron with simultaneous abdominoplasty complicated by purulent surgical infection.
本文介绍了一名55岁的病态肥胖(BMI 66.3 kg / m2)患者的成功综合治疗经验,该患者接受了皮肤脂肪围裙切除术并同时腹部成形术并发化脓性手术感染。
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引用次数: 3
Necrotizing fasciitissurgical treatment (clinical case) 坏死性筋膜组织手术治疗(临床一例)
Pub Date : 2020-09-02 DOI: 10.25199/2408-9613-2019-6-4-26-29
V. Maslennikov, V. N. Maslennikov
The article presents the experience of complex surgical treatment in patient with necrotizing fasciitis of the lower extremity. The features of the clinical picture and the course of the disease are given.
本文介绍下肢坏死性筋膜炎复杂手术治疗的经验。并对其临床表现特点及病程进行了分析。
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引用次数: 0
期刊
Wounds and wound infections. The prof. B.M. Kostyuchenok journal
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