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Karubiotec™ the Human Biobank of Guadeloupe (French West Indies): A Driver Towards Caribbean Health Research 瓜德罗普岛(法属西印度群岛)人类生物库:加勒比海健康研究的驱动力
Q2 Medicine Pub Date : 2021-09-23 DOI: 10.5334/ojb.75
Stanie Gaëte, Joelle Colat-Peyron, Colette Galbas-Frontinois, A. Marquina, Clara Lemaitre, Cécile Herrmann, A. Diédhiou, J. Deloumeaux
Karubiotec™ is a mono-site Biological Resources Center (BRC) and the only human biobank of Guadeloupe. It is an infrastructure of the University Hospital of Guadeloupe, which governed it. Located inside the hospital it is equipped with a molecular biology platform that allows all the processes from reception to preparation, storage and transfer of biological resources and their associated clinical data. These data are either part of specific research projects or of the BRC’s own research programs. After studying requests, Karubiotec™ can provide samples from blood (serum, plasma, cells, DNA, RNA), secretions and tissues for most common diseases found in the Caribbean [1], in respect of ethics requirements according to the proposed use. Paraffin blocks and slides from pathology units are also collected for some cancer sites for research reuse.
卡鲁比奥泰克™ 是一个单站点生物资源中心(BRC),也是瓜德罗普岛唯一的人类生物库。它是管理它的瓜德罗普大学医院的基础设施。它位于医院内部,配备了一个分子生物学平台,可以实现从接收到准备、存储和转移生物资源及其相关临床数据的所有过程。这些数据要么是特定研究项目的一部分,要么是BRC自己的研究项目。在研究了请求后,Karubiotec™ 根据拟议用途的伦理要求,可以为加勒比地区发现的大多数常见疾病[1]提供血液(血清、血浆、细胞、DNA、RNA)、分泌物和组织样本。病理单位的石蜡块和载玻片也被收集到一些癌症部位,用于研究重复使用。
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引用次数: 1
BCU Imaging Biobank, an Innovative Digital Resource for Biomedical Research Collecting Imaging and Clinical Data From Human Healthy and Pathological Subjects BCU成像生物库,一个创新的生物医学研究数字资源,收集人类健康和病理受试者的成像和临床数据
Q2 Medicine Pub Date : 2021-09-22 DOI: 10.5334/ojb.72
G. Esposito, Giulio Pagliari, Marco Randon, P. Mirabelli, M. Lavitrano, M. Aiello, M. Salvatore
BCU Imaging Biobank (BCU-IB) is a non-profit biorepository aimed at the collection, storage and retrieval of diagnostic images, derived descriptors and clinical data. The main scope of BCU-IB is to foster scientific advances in imaging and analysis, opening up new ways for biomedical research to diagnose, treat and potentially prevent diseases. BCU-IB collects a vast amount of images of the human body, including healthy and pathological subjects. Diagnostic images, clinical, anamnestic and demographic data are made available to study the associations between imaging phenotypes, diagnostic and prognostic factors. Curated datasets are stored and organized in a secure and reliable dedicated information systems based on the Extensible Neuroimaging Archive Toolkit (XNAT), hosted by Bio Check Up Srl.
BCU成像生物库(BCU-IB)是一家非营利性生物库,旨在收集、存储和检索诊断图像、衍生描述符和临床数据。BCU-IB的主要范围是促进成像和分析方面的科学进步,为生物医学研究诊断、治疗和潜在预防疾病开辟新的途径。BCU-IB收集了大量人体图像,包括健康和病理受试者。诊断图像、临床、记忆和人口统计数据可用于研究成像表型、诊断和预后因素之间的关系。Curated数据集存储和组织在一个安全可靠的专用信息系统中,该系统基于Bio-Check-Up Srl托管的可扩展神经成像档案工具包(XNAT)。
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引用次数: 2
Charlie Teo Foundation Brain Tumour Bank 张志贤基金会脑瘤银行
Q2 Medicine Pub Date : 2021-08-11 DOI: 10.5334/ojb.76
N. Caixeiro, J. Po, A. Zaman, M. Sughrue, C. Teo
Charlie Teo Foundation Brain Tumour Bank (CTFBTB) was started by Charlie Teo Foundation (CTF), an Australian charity funding brain cancer research. CTFBTB was established under the CTF’s research strategy of More Data – to produce and share high-quality, well-annotated, biological and clinical data that has the potential to drive further innovation and scientific breakthroughs. CTFBTB collects samples of human tissue, live cells, DNA and blood to be used for brain cancer research. CTFBTB also has a cell line repository of real-world brain tumours. Researchers can apply to use these valuable and accurate models that enable more refined analysis of the mechanisms that regulate individual patient response to treatment and allow for the further development of models for precision medicine.
Charlie Teo基金会脑肿瘤银行(CTFBTB)由Charlie TeoFoundation(CTF)发起,该基金会是一家资助癌症研究的澳大利亚慈善机构。CTFBTB是根据CTF的“更多数据”研究战略成立的,旨在产生和共享高质量、注释良好的生物学和临床数据,这些数据有可能推动进一步的创新和科学突破。CTFBTB收集人体组织、活细胞、DNA和血液样本,用于癌症研究。CTFBTB还有一个真实世界脑肿瘤的细胞系库。研究人员可以申请使用这些有价值和准确的模型,从而对调节个体患者对治疗反应的机制进行更精细的分析,并允许进一步开发精准医学模型。
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引用次数: 0
The Hannover Unified Biobank (HUB) – Centralized Standardised Biobanking at Hannover Medical School 汉诺威统一生物库(HUB)-汉诺威医学院的集中式标准化生物库
Q2 Medicine Pub Date : 2021-07-27 DOI: 10.5334/ojb.70
V. Kopfnagel, I. Bernemann, N. Klopp, M. Kersting, Nataliia Nizhegorodtseva, J. Prokein, U. Lehmann, H. Stark, T. Illig
The Hannover Unified Biobank (HUB) was established in 2012 as the central biobank of the Hannover Medical School (MHH) to provide an infrastructure for the standardised collection and storage of liquid biosamples and associated data in the context of research projects and clinical studies. For the comprehensive collection of tissue samples from the clinical routine the HUB cooperates with the MHH Institute of Pathology. All samples are connected with the associated clinical data stored in the ECRDW (Enterprise Clinical Research Data Warehouse) of the MHH. Headed by Prof. Dr. Thomas Illig the HUB developed into one of the biggest state of the art clinical biobanks in Germany and today stores about 2.88 Mio samples (mainly FFPE tissue and blood derived liquid samples) of a wide range of diseases.
汉诺威统一生物样本库(HUB)成立于2012年,是汉诺威医学院(MHH)的中央生物样本库,旨在为研究项目和临床研究中的液体生物样本和相关数据的标准化收集和存储提供基础设施。为了从临床常规中全面收集组织样本,HUB与MHH病理学研究所合作。所有样本都与存储在MHH的ECRDW(企业临床研究数据仓库)中的相关临床数据相关联。在Thomas Illig博士教授的领导下,该中心发展成为德国最大的最先进的临床生物库之一,目前储存了各种疾病的约288万个样本(主要是FFPE组织和血液来源的液体样本)。
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引用次数: 1
FarGen: Bioresource From the Faroe Genome Project 法罗:来自法罗基因组计划的生物资源
Q2 Medicine Pub Date : 2021-06-28 DOI: 10.5334/ojb.71
N. Gregersen, K. D. Apol, P. Weihe, B. Steig, G. Andorsdóttir
The Faroe Genome Project (FarGen) explores the genetic variation within the isolated population of the Faroe Islands. FarGen is an open bioresource comprising 3% of the entire Faroese population, available for further investigation of both rare and common diseases. The 1,541 volunteers include representatives from all sub-regions of the islands, and health- and socio-demographic data is collected by questionnaire, Multi-Generation Registry, Diagnostic-Registry, and National Registry. The FarGeninfrastructure is already open to research teams, and is being used in research of various complex disorders. Future aim is to reach 5000 samples i.e. 10% of the entire Faroese population.
法罗基因组计划(FarGen)探索法罗群岛孤立人口的遗传变异。FarGen是一个开放的生物资源,占整个法罗人口的3%,可用于进一步调查罕见和常见疾病。1 541名志愿人员包括来自岛屿所有次区域的代表,健康和社会人口数据是通过问卷调查、多代登记、诊断登记和国家登记收集的。FarGeninfrastructure已经向研究团队开放,并被用于各种复杂疾病的研究。未来的目标是达到5000个样本,即法罗群岛总人口的10%。
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引用次数: 3
VetBiobank, Vetmeduni Vienna: A bioresource for clinical animal biospecimens VetBiobank, Vetmeduni Vienna:临床动物生物标本的生物资源
Q2 Medicine Pub Date : 2020-11-30 DOI: 10.5334/ojb.60
I. Walter, Stefanie Burger, M. Stargardt, S. Kummer, Monika Wieser
The VetBiobank was established in 2007 as part of the VetCore Facility for Research at the University of Veterinary Medicine, Vienna. The primary objectives of the VetBiobank are (1) to achieve comprehensive collections of high quality animal samples to support research projects and (2) to provide biological reference material as controls e.g. for method verification. Currently, collections mainly contain tumor tissues and healthy reference tissues from cats and dogs, but also a small number of biospecimens from other diseases and other species, including macaque, horse, pig, and small companion animals. A total number of around 58000 individual samples are stored. The VetBiobank is partner of BBMRI.at (the Biobanking and BioMolecular resource Research Infrastructure Austria [1]), the Austrian national node of the European research infrastructure BBMRI-ERIC [2], comprising the only member with a focus on veterinary medicine. Funding statement: The VetBiobank is part of the central research facility of the University of Veterinary Medicine, which takes over personnel and running costs. Additionally, the VetBiobank was and is currently supported by two grants from the federal ministry of Austria to BBMRI.at (BMWFM GZ: 10.470/0016-II/3/2013, BMBWF GZ: 10.470/0010-V/3c/2018).
VetBiobank成立于2007年,是维也纳兽医大学VetCore研究设施的一部分。VetBiobank的主要目标是(1)实现高质量动物样本的全面收集,以支持研究项目;(2)提供生物参考材料作为对照,例如用于方法验证。目前,收集的主要是猫和狗的肿瘤组织和健康参考组织,但也有少量其他疾病和其他物种的生物标本,包括猕猴、马、猪和小型伴侣动物。总共储存了大约5.8万个单独的样本。VetBiobank是BBMRI.at(奥地利生物银行和生物分子资源研究基础设施[1])的合作伙伴,该基础设施是欧洲研究基础设施BBMRI-ERIC[2]的奥地利国家节点,是唯一专注于兽医的成员。资金声明:兽医生物库是兽医大学中央研究机构的一部分,负责承担人员和运营成本。此外,VetBiobank过去和现在都得到了奥地利联邦部向BBMRI.at提供的两项资助(BMWFM GZ:10.470/016-II/3/2013,BMBWF GZ:10.447/0010-V/3c/2018)。
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引用次数: 6
The Assistance Publique Hôpitaux de Marseille’s Biobank 马赛生物银行的公共援助医院
Q2 Medicine Pub Date : 2020-10-22 DOI: 10.5334/ojb.63
Etienne Dougy, D. Figarella-Branger, P. Morange, A. Sandre-Giovannoli, B. Lacarelle, Karine Bertaux, K. Pedeillier, N. Saut, C. Jiguet-Jiglaire, Soutsakhone Tong, K. Achache
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引用次数: 4
Biological Resource Center for Toxoplasma 弓形虫生物资源中心
Q2 Medicine Pub Date : 2020-10-20 DOI: 10.5334/ojb.61
Camila Rocaboy, M. Dardé, D. Aubert, A. Mercier, Naïma Ortis, K. Passebosc-Faure, H. Riahi, S. Escotte, Martine Gatet, I. Villena
(1) Bioresource Overview Project description The Biological Resource Center (BRC) for Toxoplasma gondii is a certified structure (NF S96-900 standard) that manages the storage of Toxoplasma gondii strains (protozoan parasite) and strain derivatives from human or animal toxoplasmosis to make them available to the scientific community. The BRC Toxoplasma works through a network of correspondents who send isolates to the parasitology departments of Reims and Limoges University hospitals (France). The managers are Pr Isabelle VILLENA (Reims) and Pr Marie-Laure DARDE (Limoges). The biological resources are stored in cryobanks located in both sites. Toxoplasma gondii strains which integrate the BRC Toxoplasma collection come from:
(1) 生物资源概述项目描述弓形虫生物资源中心(BRC)是一个经过认证的结构(NF S96-900标准),负责管理弓形虫菌株(原生动物寄生虫)和人类或动物弓形虫的菌株衍生物的储存,以供科学界使用。BRC弓形虫通过一个通讯员网络工作,他们将分离株送往兰斯和利摩日大学医院的寄生虫学部门(法国)。经理是Isabelle VILLENA(兰斯)和Marie Laure DARDE(利摩日)。生物资源储存在两个地点的冷冻库中。整合BRC弓形虫集合的弓形虫菌株来自:
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引用次数: 1
Ethical Tissue: A Bioresource Specialising in Broad Prospective Supply of Tissue from a Wide Range of Participants 伦理组织:一种生物资源,专门从广泛的参与者那里提供具有广泛前景的组织
Q2 Medicine Pub Date : 2020-04-08 DOI: 10.5334/ojb.50
Kevin Adams, W. Burrill, Joanne Mullarkey
Ethical Tissue (ET) is a Research Tissue Bank specialising in researcher led prospective collection of tissues. ET does not focus on specific conditions nor is it restricted in who it can supply. We consider requests for any type of tissue, including biofluids such as blood, serum, plasma and urine, from researchers in academia or industry from any part of the world. Tissues and biofluids are collected under generic and lasting consent, maximising reuse/sharing potential. ET also provides tissue processing services including tissue micro-arrays from both fresh frozen tissues and FFPE blocks, primary cell cultures, subcellular fractions and DNA/RNA preparations. A list of banked tissues, including biofluids, cell lines and processed samples is available on the ET website. Funding statement: The major source of income for Ethical Tissue is through cost recovery. In addition the authors would like to acknowledge the ongoing support of the University of Bradford.
伦理组织(ET)是一个研究组织库,专门从事研究人员领导的组织前瞻性收集。ET不关注特定条件,也不限制其可以向谁提供。我们考虑来自世界任何地方的学术界或工业界研究人员对任何类型组织的请求,包括血液、血清、血浆和尿液等生物流体。组织和生物流体是在通用和持久同意的情况下收集的,最大限度地提高了重复使用/共享的潜力。ET还提供组织加工服务,包括新鲜冷冻组织和FFPE块的组织微阵列、原代细胞培养物、亚细胞组分和DNA/RNA制剂。ET网站上有一份储存组织的清单,包括生物流体、细胞系和处理过的样本。资金声明:伦理组织的主要收入来源是通过成本回收。此外,作者还要感谢布拉德福德大学的持续支持。
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引用次数: 0
Centre de Ressources Biologiques-Tumorothèque: Bioresources and Associated Clinical Data Dedicated to Translational Research in Oncology at the Institut de Cancérologie de l’Ouest, France 法国西部癌症研究所生物肿瘤资源中心:致力于肿瘤转化研究的生物资源和相关临床数据
Q2 Medicine Pub Date : 2020-04-07 DOI: 10.5334/ojb.62
D. Heymann, O. Kerdraon, V. Verrièle, Estelle Verhille, Vanessa Veron, M. Vitré, Florian Delmas, Cécile Henry, Yann Gouy, M. Amiand, J. Bard
The Centre de Ressources Biologiques-Tumorotheque ICO is a biobank integrated in a clinical cancer center (ICO, Institut de Cancerologie de l’Ouest, Saint-Herblain, FR) that collects tissues (snap frozen, FFPE, TMA) and biological (serum, plasma, DNA, RNA, stools, etc) samples from oncology patients and dedicated to translational research. The biobank started its activities in 2002 and is certified NF S 96 900. Activities are framed by a quality management system with established and validated SOPs for all work procedures. Samples stored into the biobank are available for both academic as well as commercial researchers, through a defined access procedure. Currently the bioresources consist in more than 99.500 samples with informed consent and associated clinical data.
生物资源中心-肿瘤中心ICO是一个整合在临床癌症中心(ICO, Institut de Cancerologie de l 'Ouest, Saint-Herblain, FR)的生物样本库,收集肿瘤患者的组织(速冻、FFPE、TMA)和生物(血清、血浆、DNA、RNA、粪便等)样本,并致力于转化研究。该生物库于2002年开始活动,并通过了NF S 96 900认证。活动由质量管理体系框架,所有工作程序都有已建立和验证的标准操作规程。存储在生物库中的样本可以通过一个确定的访问程序提供给学术和商业研究人员。目前,生物资源包括99.500多个样本,并有知情同意和相关临床数据。
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引用次数: 9
期刊
Open Journal of Bioresources
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