C. Lewis, S. McQuaid, Priscilla Clark, P. Murray, T. McGuigan, Christine Greene, Bronagh Coulter, K. Mills, J. James
The Northern Ireland Biobank (NIB) was established in 2011 as a joint initiative between Queen’s University Belfast and Belfast Health and Social Care Trust to provide the infrastructure for the standardised collection and storage of high quality, well annotated human tissue samples, with matched bloods and bodily fluids to underpin cancer research in Northern Ireland and beyond. The NIB has been instrumental in supporting translational research locally, nationally and internationally with a number of key achievements to date. The vision of NIB is to develop an internationally recognised biobank network within Northern Ireland which collects, stores and distributes high quality, clinically annotated biospecimens for biomarker research to benefit cancer patients. Funding statement: NIB receives core funding from the Health and Social Care Research and Development Division of the Public Health Agency in Northern Ireland with charitable funding from Friends of the Cancer Centre. NIB previously received charitable funding from Cancer Research UK and Prostate Cancer UK.
{"title":"The Northern Ireland Biobank: A Cancer Focused Repository of Science","authors":"C. Lewis, S. McQuaid, Priscilla Clark, P. Murray, T. McGuigan, Christine Greene, Bronagh Coulter, K. Mills, J. James","doi":"10.5334/OJB.47","DOIUrl":"https://doi.org/10.5334/OJB.47","url":null,"abstract":"The Northern Ireland Biobank (NIB) was established in 2011 as a joint initiative between Queen’s University Belfast and Belfast Health and Social Care Trust to provide the infrastructure for the standardised collection and storage of high quality, well annotated human tissue samples, with matched bloods and bodily fluids to underpin cancer research in Northern Ireland and beyond. The NIB has been instrumental in supporting translational research locally, nationally and internationally with a number of key achievements to date. The vision of NIB is to develop an internationally recognised biobank network within Northern Ireland which collects, stores and distributes high quality, clinically annotated biospecimens for biomarker research to benefit cancer patients. Funding statement: NIB receives core funding from the Health and Social Care Research and Development Division of the Public Health Agency in Northern Ireland with charitable funding from Friends of the Cancer Centre. NIB previously received charitable funding from Cancer Research UK and Prostate Cancer UK.","PeriodicalId":36769,"journal":{"name":"Open Journal of Bioresources","volume":"5 1","pages":"9"},"PeriodicalIF":0.0,"publicationDate":"2018-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44868239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. J. V. Os, Y. Ruigrok, J. Manniën, E. Dijk, P. Koudstaal, G. Luijckx, P. Nederkoorn, R. Oostenbrugge, M. Visser, L. Kappelle, A. Algra, M. Wermer
The Dutch Parelsnoer Institute-Cerebrovascular accident (CVA) Study is part of the Parelsnoer Institute (PSI), initiated in 2007 by the Netherlands Federation of University Medical Centers (NFU). PSI is a cooperation of all eight Dutch University Medical Centers (UMCs) and aims at building large prospectively collected datasets with uniformly and standardized storage of biomaterials for complex diseases. Currently, PSI covers 18 disease-specific cohorts called ‘Pearls’, and this number is still growing. One of these cohorts is the Stroke or CVA Pearl. For each of the cohorts, PSI offers the UMCs an infrastructure and standard procedures for storing the specific biomaterials in their certified biobanks. Clinical data are stored in a central database after being pseudonymized to ensure patient privacy. For the Parelsnoer Institute-CVA Study, blood for genetic analysis, serum and plasma are collected according to nationally agreed standards. Currently (November 2017) the Stroke Pearl has stored blood samples with prospectively obtained clinical data of around 6000 patients in all UMCs combined. Blood samples and data are available for all researchers with a methodologically valid research proposal. Funding statement: PSI was founded in 2007 with a five year grant from the Dutch Government. From 2011 until now PSI is funded and facilitated by the Netherlands Federation of University Medical Centers (NFU) and its member institutions, independent of external funds. Additional funds from governmental sources, industry sponsors and charity are used for the analysis on the existing data and the expansion of PSI with new diseases.
{"title":"Dutch Parelsnoer Institute-Cerebrovascular Accident (CVA) Study: A Large Multicenter Clinical Biobank with Standardized Collection and Storage","authors":"H. J. V. Os, Y. Ruigrok, J. Manniën, E. Dijk, P. Koudstaal, G. Luijckx, P. Nederkoorn, R. Oostenbrugge, M. Visser, L. Kappelle, A. Algra, M. Wermer","doi":"10.5334/OJB.41","DOIUrl":"https://doi.org/10.5334/OJB.41","url":null,"abstract":"The Dutch Parelsnoer Institute-Cerebrovascular accident (CVA) Study is part of the Parelsnoer Institute (PSI), initiated in 2007 by the Netherlands Federation of University Medical Centers (NFU). PSI is a cooperation of all eight Dutch University Medical Centers (UMCs) and aims at building large prospectively collected datasets with uniformly and standardized storage of biomaterials for complex diseases. Currently, PSI covers 18 disease-specific cohorts called ‘Pearls’, and this number is still growing. One of these cohorts is the Stroke or CVA Pearl. For each of the cohorts, PSI offers the UMCs an infrastructure and standard procedures for storing the specific biomaterials in their certified biobanks. Clinical data are stored in a central database after being pseudonymized to ensure patient privacy. For the Parelsnoer Institute-CVA Study, blood for genetic analysis, serum and plasma are collected according to nationally agreed standards. Currently (November 2017) the Stroke Pearl has stored blood samples with prospectively obtained clinical data of around 6000 patients in all UMCs combined. Blood samples and data are available for all researchers with a methodologically valid research proposal. Funding statement: PSI was founded in 2007 with a five year grant from the Dutch Government. From 2011 until now PSI is funded and facilitated by the Netherlands Federation of University Medical Centers (NFU) and its member institutions, independent of external funds. Additional funds from governmental sources, industry sponsors and charity are used for the analysis on the existing data and the expansion of PSI with new diseases.","PeriodicalId":36769,"journal":{"name":"Open Journal of Bioresources","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42232625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bimetra Biobank is the central high quality biorepository of University Hospital Ghent in collaboration with Ghent University (Belgium). Fully operational since 2015 in a new state-of-the-art biobank facility, Bimetra Biobank acts as a core facility for researchers and third parties looking for high-quality annotated clinical biospecimens. Bimetra Biobank stores about 120.000 clinical samples, both historical collections and prospective collections (disease-based collections, population-based collections and basic research collections) within well-defined and ethically approved research projects. Through a clear governance structure compliant with applicable laws, collections are operationally managed by Bimetra biobank personnel and samples releases are coordinated through collection specific coordinators and advisory boards. Biobank collections are open for collaborations to the international scientific community.
{"title":"Bimetra Biobank: A High Quality Biobank Facility to Stimulate Translational Biomedical Research","authors":"V. T'joen, Sara Phlypo, S. Bekaert","doi":"10.5334/OJB.37","DOIUrl":"https://doi.org/10.5334/OJB.37","url":null,"abstract":"Bimetra Biobank is the central high quality biorepository of University Hospital Ghent in collaboration with Ghent University (Belgium). Fully operational since 2015 in a new state-of-the-art biobank facility, Bimetra Biobank acts as a core facility for researchers and third parties looking for high-quality annotated clinical biospecimens. Bimetra Biobank stores about 120.000 clinical samples, both historical collections and prospective collections (disease-based collections, population-based collections and basic research collections) within well-defined and ethically approved research projects. Through a clear governance structure compliant with applicable laws, collections are operationally managed by Bimetra biobank personnel and samples releases are coordinated through collection specific coordinators and advisory boards. Biobank collections are open for collaborations to the international scientific community.","PeriodicalId":36769,"journal":{"name":"Open Journal of Bioresources","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48415646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Geiger, S. Both, S. Kircher, Michael Neumann, A. Rosenwald, R. Jahns
The ibdw was established in 2011 as one of 5 centralised national biobanks in Germany within the framework of the governmental funding program “Nationale Biobank-Initiative”. The ibdw is a joint core facility of both, the University Hospital and the Julius-Maximilians-University Wurzburg and acts as a faculty-wide service provider of human biological material for medical research. From the outset main emphasis was placed on comprehensive automation and seamless integration of sample collection in clinical routine workflows thereby securing highest quality standards. The ibdw collects fluid and tissue samples in parallel from patients, based on a broad informed consent, hence not limiting future research use.
{"title":"Hospital-integrated Biobanking as a Service – The Interdisciplinary Bank of Biomaterials and Data Wuerzburg (ibdw)","authors":"J. Geiger, S. Both, S. Kircher, Michael Neumann, A. Rosenwald, R. Jahns","doi":"10.5334/OJB.38","DOIUrl":"https://doi.org/10.5334/OJB.38","url":null,"abstract":"The ibdw was established in 2011 as one of 5 centralised national biobanks in Germany within the framework of the governmental funding program “Nationale Biobank-Initiative”. The ibdw is a joint core facility of both, the University Hospital and the Julius-Maximilians-University Wurzburg and acts as a faculty-wide service provider of human biological material for medical research. From the outset main emphasis was placed on comprehensive automation and seamless integration of sample collection in clinical routine workflows thereby securing highest quality standards. The ibdw collects fluid and tissue samples in parallel from patients, based on a broad informed consent, hence not limiting future research use.","PeriodicalId":36769,"journal":{"name":"Open Journal of Bioresources","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45389813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Goethals, A. D. Wilde, Katrien Lesage, E. Smits, P. Pauwels, M. Peeters
Tumorbank@UZA is an academic hospital integrated biobank that collects tissue, blood and urine samples from oncology patients. We work according to a quality management system and have established SOPs for all work procedures in the biobank. Tumorbank@UZA is funded by the National Cancer Plan, an initiative from the Belgian government since 2009. Samples from our biobank are available for both academic as well as commercial researchers, through a well-established access procedure. Currently the collection consists of more than 85.000 samples of more than 8000 patients. Funding statement: Tumorbank@UZA is funded by the National Cancer Plan (initiative 27) from the Ministry of Health of the Belgian Federal Government.
{"title":"Tumorbank@uza: A Collection of Tissue, Fluid Samples and Associated Data of Oncology Patients for the Use in Translational Research","authors":"S. Goethals, A. D. Wilde, Katrien Lesage, E. Smits, P. Pauwels, M. Peeters","doi":"10.5334/OJB.30","DOIUrl":"https://doi.org/10.5334/OJB.30","url":null,"abstract":"Tumorbank@UZA is an academic hospital integrated biobank that collects tissue, blood and urine samples from oncology patients. We work according to a quality management system and have established SOPs for all work procedures in the biobank. Tumorbank@UZA is funded by the National Cancer Plan, an initiative from the Belgian government since 2009. Samples from our biobank are available for both academic as well as commercial researchers, through a well-established access procedure. Currently the collection consists of more than 85.000 samples of more than 8000 patients. Funding statement: Tumorbank@UZA is funded by the National Cancer Plan (initiative 27) from the Ministry of Health of the Belgian Federal Government.","PeriodicalId":36769,"journal":{"name":"Open Journal of Bioresources","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42687700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Reed, J. Saunus, K. Ferguson, Colleen Niland, P. Simpson, S. Lakhani
The Brisbane Breast Bank (BBB) was established in 2005 with a view to collecting surplus tissue from every breast surgery patient at the Royal Brisbane and Women’s Hospital. This not-for-profit biobank provides resources on a collaborative basis, supporting local, national and international studies. The resource prides itself on its comprehensive clinico-pathology sample annotation. Since its inception, the remit of the BBB has expanded to the prospective collection of serial blood samples from patients at high risk of recurrence, and the collection of blood and tumour tissue from metastatic patients.
{"title":"The Brisbane Breast Bank","authors":"A. Reed, J. Saunus, K. Ferguson, Colleen Niland, P. Simpson, S. Lakhani","doi":"10.5334/OJB.33","DOIUrl":"https://doi.org/10.5334/OJB.33","url":null,"abstract":"The Brisbane Breast Bank (BBB) was established in 2005 with a view to collecting surplus tissue from every breast surgery patient at the Royal Brisbane and Women’s Hospital. This not-for-profit biobank provides resources on a collaborative basis, supporting local, national and international studies. The resource prides itself on its comprehensive clinico-pathology sample annotation. Since its inception, the remit of the BBB has expanded to the prospective collection of serial blood samples from patients at high risk of recurrence, and the collection of blood and tumour tissue from metastatic patients.","PeriodicalId":36769,"journal":{"name":"Open Journal of Bioresources","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43212135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Manders, J. Lutomski, C. Smit, D. Swinkels, G. Zielhuis
The Radboud Biobank offers disease-based biobanks a centralized facility to optimize the use and distribution of biomaterial for scientific research. Notably, two population biobanks are also included in this collection. All collections are professionally and sustainably maintained using high-quality and secure standardized protocols for ICT, legal-ethical aspects, sample collection, processing and storage, communication and distribution. The Radboud Biobank includes biomaterial (e.g. DNA, serum, plasma, tissue, urine and faeces – depending on the specific patient group), images, associated clinical data (patient, disease-specific and phenotypic data) and derived information (genotypic data, microarray gene expressions). Patient advocates and other relevant stakeholders are actively involved in the governance of the Radboud Biobank. Funding statement: The Radboud Biobank was implemented by the Radboudumc Executive Board as part of the university research infrastructure. It is a central facility for the Radboudumc, with guaranteed central support for at least 15 years. A governing strategic board, encompassing relevant stakeholder groups, oversees the operations of the Radboud Biobank. Two patient representatives are included in this strategic board, and one holds the position of chairperson.
{"title":"The Radboud Biobank: A Central Facility for Disease-Based Biobanks to Optimise Use and Distribution of Biomaterial for Scientific Research in the Radboud University Medical Center, Nijmegen","authors":"P. Manders, J. Lutomski, C. Smit, D. Swinkels, G. Zielhuis","doi":"10.5334/OJB.36","DOIUrl":"https://doi.org/10.5334/OJB.36","url":null,"abstract":"The Radboud Biobank offers disease-based biobanks a centralized facility to optimize the use and distribution of biomaterial for scientific research. Notably, two population biobanks are also included in this collection. All collections are professionally and sustainably maintained using high-quality and secure standardized protocols for ICT, legal-ethical aspects, sample collection, processing and storage, communication and distribution. The Radboud Biobank includes biomaterial (e.g. DNA, serum, plasma, tissue, urine and faeces – depending on the specific patient group), images, associated clinical data (patient, disease-specific and phenotypic data) and derived information (genotypic data, microarray gene expressions). Patient advocates and other relevant stakeholders are actively involved in the governance of the Radboud Biobank. Funding statement: The Radboud Biobank was implemented by the Radboudumc Executive Board as part of the university research infrastructure. It is a central facility for the Radboudumc, with guaranteed central support for at least 15 years. A governing strategic board, encompassing relevant stakeholder groups, oversees the operations of the Radboud Biobank. Two patient representatives are included in this strategic board, and one holds the position of chairperson.","PeriodicalId":36769,"journal":{"name":"Open Journal of Bioresources","volume":"5 1","pages":"2"},"PeriodicalIF":0.0,"publicationDate":"2018-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46190834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Li Zhou, A. Yuksel, O. Markovich, Natalie Gabrael, D. Catchpoole
The Tumor Bank at The Children’s Hospital at Westmead was established in 1998 with the purpose of facilitating research into childhood malignancy through the active provision of well annotated, ethically collected tissue samples and providing a pathway for the Children Hospital at Westmead to engage in leading research initiatives, supporting international investigations and clinical trials. Within 20 years practice as a single institute biorepository, The Tumour Bank has established standard operating procedures for collection of tissue, blood and bone marrow that were integrated into routine patient management systems. In addition, three main operational areas have been developed: collection of biospecimens and written consent; management of clinical data and biospecimen inventory database; and implementation of an open access policy to support childhood cancer research around the world. Regulatory oversight is provided by the Tumour Bank Committee, Human Research Ethics Committee and Governance Department. This concerted effort has resulted in collecting 20340 specimens from 3788 patients within 20 years, and The Tumour bank has supported over 108 national and international research projects, and contributed to over 70 peer-reviewed publications to date, with a mean time–to-publication of 19.1 ± 9.0 months and average Impact Factor of 6.11 ± 4.53. In conclusion, the Children’s Hospital at Westmead Tumour Bank has demonstrated a sustained single institutional biorepository model for facilitating translational research of rare cancer. It has provided strong evidence that integration of a single institutional biobank into standard clinical practices would be the long-term pathway of valuable bio-resource for rare cancer research.
The Children’s Hospital at Westmead的肿瘤银行成立于1998年，其目的是通过积极提供精心注释的、合乎道德的组织样本来促进儿童恶性肿瘤的研究，并为Westmead儿童医院参与领先的研究倡议、支持国际调查和临床试验提供途径。在作为单一机构生物储存库的20年实践中，肿瘤银行建立了组织、血液和骨髓收集的标准操作程序，并将其纳入常规患者管理系统。此外，还发展了三个主要业务领域:收集生物标本和书面同意;临床数据和生物标本库存数据库的管理;实施开放获取政策，支持世界各地的儿童癌症研究。监管监督由肿瘤银行委员会、人类研究伦理委员会和治理部提供。在这一共同努力下，肿瘤库在20年内从3788名患者中收集了20340个标本，支持了108多个国家和国际研究项目，迄今为止发表了70多篇同行评议的论文，平均发表时间为19.1±9.0个月，平均影响因子为6.11±4.53。总之，韦斯特米德肿瘤银行的儿童医院已经展示了一种促进罕见癌症转化研究的持续的单一机构生物存储模式。它提供了强有力的证据，证明将一个单一的机构生物库整合到标准的临床实践中，将是罕见癌症研究宝贵生物资源的长期途径。
{"title":"The Tumour Bank at the Children’s Hospital at Westmead: An Australian Paediatric Cancer Biorepository","authors":"Li Zhou, A. Yuksel, O. Markovich, Natalie Gabrael, D. Catchpoole","doi":"10.5334/OJB.34","DOIUrl":"https://doi.org/10.5334/OJB.34","url":null,"abstract":"The Tumor Bank at The Children’s Hospital at Westmead was established in 1998 with the purpose of facilitating research into childhood malignancy through the active provision of well annotated, ethically collected tissue samples and providing a pathway for the Children Hospital at Westmead to engage in leading research initiatives, supporting international investigations and clinical trials. Within 20 years practice as a single institute biorepository, The Tumour Bank has established standard operating procedures for collection of tissue, blood and bone marrow that were integrated into routine patient management systems. In addition, three main operational areas have been developed: collection of biospecimens and written consent; management of clinical data and biospecimen inventory database; and implementation of an open access policy to support childhood cancer research around the world. Regulatory oversight is provided by the Tumour Bank Committee, Human Research Ethics Committee and Governance Department. This concerted effort has resulted in collecting 20340 specimens from 3788 patients within 20 years, and The Tumour bank has supported over 108 national and international research projects, and contributed to over 70 peer-reviewed publications to date, with a mean time–to-publication of 19.1 ± 9.0 months and average Impact Factor of 6.11 ± 4.53. In conclusion, the Children’s Hospital at Westmead Tumour Bank has demonstrated a sustained single institutional biorepository model for facilitating translational research of rare cancer. It has provided strong evidence that integration of a single institutional biobank into standard clinical practices would be the long-term pathway of valuable bio-resource for rare cancer research.","PeriodicalId":36769,"journal":{"name":"Open Journal of Bioresources","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43173565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fecarotta Emanuela, S. Giovanna, Garofalo Giuseppa Maria, Damiani Gianfranca, Piazza Angela, Sacco Massimiliano, Renda Disma, G. Antonino, Cristian Catalano, M. Aurelio, Renda Maria Concetta
The research biobank “Anna Maria Ferraro Cutino” AOR-villa Sofia-Cervello, started in 2010 by a grant of the Sicilian Department of Health. Within the biobank are collected, characterized, stored and distributed amniotic fluids (AF) from amniocentesis performed for maternal age. Patients choose to donate to the biobank the first 3 ml of AF that cannot be used for prenatal diagnosis. AF and donor data are anonymously archived in a database, according to the standard ethical principles. Collateral biobanks are present to collect, storage and manage donor sera and DNA samples, to perform microbiological and genetic tests necessary for the unit release. Funding Statement: From 2009 to date this work is supported by: 1. “Franco e Piera Cutino” onlus Foundation, Palermo (Italy); 2. Health Department Sicilian Region; 3. Productive Activities Department Sicilian Region; 4. AOR “Villa Sofia –Cervello” (Palermo).
“安娜·玛丽亚·费拉罗·库蒂诺”研究生物库于2010年由西西里岛卫生部拨款启动。在生物库中收集、鉴定、储存和分发的羊水(AF)来自于孕妇年龄进行的羊膜穿刺术。患者选择将不能用于产前诊断的前3ml房颤捐献给生物库。根据标准的伦理原则，AF和捐赠者的数据匿名保存在数据库中。附属生物库用于收集、储存和管理供体血清和DNA样本，进行单位释放所需的微生物和基因检测。资助说明:2009年至今，本研究由以下机构资助:“Franco e Piera Cutino”onlus基金会，巴勒莫(意大利);2. 西西里岛地区卫生局;3.西西里岛地区生产活动司;4. AOR“Villa Sofia -Cervello”(巴勒莫)。
{"title":"Amniotic Fluid Cells Biobank for Research on Fetal Mesenchymal Stem Cells","authors":"Fecarotta Emanuela, S. Giovanna, Garofalo Giuseppa Maria, Damiani Gianfranca, Piazza Angela, Sacco Massimiliano, Renda Disma, G. Antonino, Cristian Catalano, M. Aurelio, Renda Maria Concetta","doi":"10.5334/OJB.35","DOIUrl":"https://doi.org/10.5334/OJB.35","url":null,"abstract":"The research biobank “Anna Maria Ferraro Cutino” AOR-villa Sofia-Cervello, started in 2010 by a grant of the Sicilian Department of Health. Within the biobank are collected, characterized, stored and distributed amniotic fluids (AF) from amniocentesis performed for maternal age. Patients choose to donate to the biobank the first 3 ml of AF that cannot be used for prenatal diagnosis. AF and donor data are anonymously archived in a database, according to the standard ethical principles. Collateral biobanks are present to collect, storage and manage donor sera and DNA samples, to perform microbiological and genetic tests necessary for the unit release. Funding Statement: From 2009 to date this work is supported by: 1. “Franco e Piera Cutino” onlus Foundation, Palermo (Italy); 2. Health Department Sicilian Region; 3. Productive Activities Department Sicilian Region; 4. AOR “Villa Sofia –Cervello” (Palermo).","PeriodicalId":36769,"journal":{"name":"Open Journal of Bioresources","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70694412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Quinlan, E. Lawrence, Amir Pourabdolla, J. Sims, A. Gander, B. Fuller, B. Thomson, J. Garibaldi, B. Davidson
The UKCRC Tissue Directory and Coordination Centre was established to improve access to and utilisation of UK human tissue samples for medical research. The key output of the Centre is the creation of the UK’s first pan-disease Tissue Directory ( https://directory.biobankinguk.org/ ). Any researcher can search the Directory based on a series of simple key words including disease classification, age, sex, sample type, preservation details, quality indicators and datasets available. The Directory as of April 2017 contains 100 Bioresources. Researchers seeking fresh samples can also search for facilities that offer bespoke collection services. Future work of the Centre will be to explore greater standardisation of biobanking activities across the UK and to facilitate an inter-connected research infrastructure related to the use of human biosamples. Funding statement: The Centre is funded by a consortium, the UK Clinical Research Collaboration, and administered by the Medical Research Council, grant number: MR/M501748/1.
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