Pub Date : 2024-12-01Epub Date: 2024-06-18DOI: 10.1016/j.jisako.2024.06.002
Gerald Joseph Zeng, Ying Hao, Denny Tjiauw Tjoen Lie
Objective: There is paucity of literature on the impact of patients' gender on recovery and treatment success after arthroscopic rotator cuff repair. This study investigates the effect of gender on patient-reported outcomes preoperatively and postoperatively (minimum 2 years), and to determine if gender affects the attainment of patient-acceptable symptomatic state (PASS) thresholds.
Methods: 266 patients (117 males, 149 females), who underwent primary arthroscopic rotator cuff repair for atraumatic, full-thickness tears, were included. Functional outcomes and pain scores were collected preoperatively and postoperatively. Percentage of attainment of PASS for the various outcome scores was calculated and compared between males and females.
Results: Women had statistically significantly poorer functional outcome and pain scores preoperatively and at 1 and 2 years postoperatively (P < 0.01). They also experienced less improvement in outcome scores throughout the postoperative period. Women had statistically significantly lower rates of PASS attainment at 2 years postoperatively.
Conclusion: Women experience greater pain and poorer shoulder function compared with men preoperatively, and up to 2 years postoperatively. Women are less likely to achieve PASS thresholds postoperatively, compared to their male counterparts.
{"title":"Gender-based differences in mid-term clinical outcomes and patient acceptable symptomatic state attainment after arthroscopic rotator cuff repair: Minimum 2-year follow up.","authors":"Gerald Joseph Zeng, Ying Hao, Denny Tjiauw Tjoen Lie","doi":"10.1016/j.jisako.2024.06.002","DOIUrl":"10.1016/j.jisako.2024.06.002","url":null,"abstract":"<p><strong>Objective: </strong>There is paucity of literature on the impact of patients' gender on recovery and treatment success after arthroscopic rotator cuff repair. This study investigates the effect of gender on patient-reported outcomes preoperatively and postoperatively (minimum 2 years), and to determine if gender affects the attainment of patient-acceptable symptomatic state (PASS) thresholds.</p><p><strong>Methods: </strong>266 patients (117 males, 149 females), who underwent primary arthroscopic rotator cuff repair for atraumatic, full-thickness tears, were included. Functional outcomes and pain scores were collected preoperatively and postoperatively. Percentage of attainment of PASS for the various outcome scores was calculated and compared between males and females.</p><p><strong>Results: </strong>Women had statistically significantly poorer functional outcome and pain scores preoperatively and at 1 and 2 years postoperatively (P < 0.01). They also experienced less improvement in outcome scores throughout the postoperative period. Women had statistically significantly lower rates of PASS attainment at 2 years postoperatively.</p><p><strong>Conclusion: </strong>Women experience greater pain and poorer shoulder function compared with men preoperatively, and up to 2 years postoperatively. Women are less likely to achieve PASS thresholds postoperatively, compared to their male counterparts.</p><p><strong>Study design: </strong>Retrospective Cohort Study.</p><p><strong>Level of evidence: </strong>III.</p>","PeriodicalId":36847,"journal":{"name":"Journal of ISAKOS Joint Disorders & Orthopaedic Sports Medicine","volume":" ","pages":"100283"},"PeriodicalIF":2.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141427820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-01Epub Date: 2024-06-20DOI: 10.1016/j.jisako.2024.06.007
Jason H Kim, Richard M Danilkowicz, Zachary D Meeker, Kyle R Wagner, Zeeshan A Khan, Jorge Chahla
Objectives: The purpose of this study was to assess the educational reliability and quality of videos shared on YouTube regarding medial collateral ligament (MCL) injuries of the knee.
Methods: Using the search keywords "medial collateral ligament" on YouTube, the first 50 videos were evaluated by two independent reviewers. Video characteristics were extracted, and each video was categorized by upload source and content type. Three scoring systems were used to evaluate the videos: the Journal of the American Medical Association (JAMA) Benchmark Score to assess a video's reliability; the Global Quality Score (GQS) to assess educational quality; the novel MCL Specific Score (MCL-SS) to assess MCL-specific content quality. Linear regression analyses were conducted to explore relationships between video characteristics and scores.
Results: Collectively, the videos were viewed 5,759,427 times with a mean number of views per video of 115,189 ± 177,861. The mean JAMA score was 1.8, GQS was 2.1, and MCL-SS was 5.6, indicating both poor reliability and quality. Only videos uploaded by physicians showed a statistically significantly higher mean MCL-SS (P = 0.032) but were still of low quality with a mean MCL-SS of 9.2 ± 5.9. Multivariate linear regression revealed that videos uploaded by physicians were statistically significant predictors of greater MCL-SS (β = 4.108; P = 0.029). Longer video durations were statistically significant predictors of greater GQS (β = 0.001; P = 0.002) and MCL-SS (β = 0.007; P < 0.001).
Conclusions: YouTube videos regarding MCL injuries, despite their popularity, were found to be on average having poor overall reliability and quality as measured by JAMA, GQS and MCL-SS.
{"title":"Evaluating the reliability and quality of YouTube videos regarding medial collateral ligament knee injury as a patient education resource.","authors":"Jason H Kim, Richard M Danilkowicz, Zachary D Meeker, Kyle R Wagner, Zeeshan A Khan, Jorge Chahla","doi":"10.1016/j.jisako.2024.06.007","DOIUrl":"10.1016/j.jisako.2024.06.007","url":null,"abstract":"<p><strong>Objectives: </strong>The purpose of this study was to assess the educational reliability and quality of videos shared on YouTube regarding medial collateral ligament (MCL) injuries of the knee.</p><p><strong>Methods: </strong>Using the search keywords \"medial collateral ligament\" on YouTube, the first 50 videos were evaluated by two independent reviewers. Video characteristics were extracted, and each video was categorized by upload source and content type. Three scoring systems were used to evaluate the videos: the Journal of the American Medical Association (JAMA) Benchmark Score to assess a video's reliability; the Global Quality Score (GQS) to assess educational quality; the novel MCL Specific Score (MCL-SS) to assess MCL-specific content quality. Linear regression analyses were conducted to explore relationships between video characteristics and scores.</p><p><strong>Results: </strong>Collectively, the videos were viewed 5,759,427 times with a mean number of views per video of 115,189 ± 177,861. The mean JAMA score was 1.8, GQS was 2.1, and MCL-SS was 5.6, indicating both poor reliability and quality. Only videos uploaded by physicians showed a statistically significantly higher mean MCL-SS (P = 0.032) but were still of low quality with a mean MCL-SS of 9.2 ± 5.9. Multivariate linear regression revealed that videos uploaded by physicians were statistically significant predictors of greater MCL-SS (β = 4.108; P = 0.029). Longer video durations were statistically significant predictors of greater GQS (β = 0.001; P = 0.002) and MCL-SS (β = 0.007; P < 0.001).</p><p><strong>Conclusions: </strong>YouTube videos regarding MCL injuries, despite their popularity, were found to be on average having poor overall reliability and quality as measured by JAMA, GQS and MCL-SS.</p><p><strong>Level of evidence: </strong>III.</p><p><strong>Study design: </strong>Cross-sectional Study.</p>","PeriodicalId":36847,"journal":{"name":"Journal of ISAKOS Joint Disorders & Orthopaedic Sports Medicine","volume":" ","pages":"100288"},"PeriodicalIF":2.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141440937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-01Epub Date: 2024-06-17DOI: 10.1016/j.jisako.2024.06.005
Patricia Nuñez de Aysa, Jonas Grani Garðarsson, Ayyoub Al-Dolaymi, Marcelo Bordalo-Rodrigues, Markus Laupheimer, Theodorakys Marín Fermín
This is the case of an 18-year-old male professional soccer player, an attacking midfielder, who presented acute-onset pain in his right thigh during a training match but continued playing and training until the end of the session. Two weeks after the initial symptoms, the athlete's pain increased after kicking the ball and stopping training. He came for consultation a week later with tenderness in his right thigh and impaired gait. A 3 cm gap in his right mid-quadriceps muscle and tenderness during resisted knee extension and leg raises with no hip or knee range of motion limitations were observed on physical examination. He was scheduled for magnetic resonance imaging (MRI) after the consultation, revealing an acute-on-chronic type 2A lateral muscle tear of the distal rectus femoris. A 2 ml seroma aspiration was performed five weeks after the initial injury with a subsequent intra-lesional 1 ml liquid leukocyte-rich platelet-rich plasma (LR-PRP) injection using intermittent ultrasound guidance within 5 min after preparation. The LR-PRP preparation was classified as 3 14-1 3-0 0 according to the Universal Coding System (UCS) by Kon et al. Nine physiotherapy sessions, including an initial assessment, were conducted over five weeks. The rehabilitation started with pulley exercises with hip flexion, tension arch, leg extension, and squatting with supporting exercises for core and hip strength, with a gradual increase in loading. As the player's symptoms improved, he started doing eccentric exercises such as the reverse Nordics and leg extension. He also followed a running program, gradually increasing speed to a full sprint without pain or irritation. The return-to-sports clearance consultation was conducted seven weeks after the injury, previously confirming satisfactory healing on an MRI. The patient was cleared after passing the Rehabilitation Department battery tests and physical examination. The patient was asymptomatic and had no complaints despite his right quadriceps gap, returning to competition nine weeks after injury. After a one-year follow-up, the patient remains playing at a competitive level, asymptomatic, with no reported reinjury. Adequate reporting of rehabilitation programs and PRP injection characterization is crucial for future research quality improvement and reproducibility.
{"title":"Leukocyte-Rich Platelet-Rich Plasma Injection in an Acute-on-Chronic Rectus Femoris Injury of a Professional Soccer Player: A Case Report.","authors":"Patricia Nuñez de Aysa, Jonas Grani Garðarsson, Ayyoub Al-Dolaymi, Marcelo Bordalo-Rodrigues, Markus Laupheimer, Theodorakys Marín Fermín","doi":"10.1016/j.jisako.2024.06.005","DOIUrl":"10.1016/j.jisako.2024.06.005","url":null,"abstract":"<p><p>This is the case of an 18-year-old male professional soccer player, an attacking midfielder, who presented acute-onset pain in his right thigh during a training match but continued playing and training until the end of the session. Two weeks after the initial symptoms, the athlete's pain increased after kicking the ball and stopping training. He came for consultation a week later with tenderness in his right thigh and impaired gait. A 3 cm gap in his right mid-quadriceps muscle and tenderness during resisted knee extension and leg raises with no hip or knee range of motion limitations were observed on physical examination. He was scheduled for magnetic resonance imaging (MRI) after the consultation, revealing an acute-on-chronic type 2A lateral muscle tear of the distal rectus femoris. A 2 ml seroma aspiration was performed five weeks after the initial injury with a subsequent intra-lesional 1 ml liquid leukocyte-rich platelet-rich plasma (LR-PRP) injection using intermittent ultrasound guidance within 5 min after preparation. The LR-PRP preparation was classified as 3 14-1 3-0 0 according to the Universal Coding System (UCS) by Kon et al. Nine physiotherapy sessions, including an initial assessment, were conducted over five weeks. The rehabilitation started with pulley exercises with hip flexion, tension arch, leg extension, and squatting with supporting exercises for core and hip strength, with a gradual increase in loading. As the player's symptoms improved, he started doing eccentric exercises such as the reverse Nordics and leg extension. He also followed a running program, gradually increasing speed to a full sprint without pain or irritation. The return-to-sports clearance consultation was conducted seven weeks after the injury, previously confirming satisfactory healing on an MRI. The patient was cleared after passing the Rehabilitation Department battery tests and physical examination. The patient was asymptomatic and had no complaints despite his right quadriceps gap, returning to competition nine weeks after injury. After a one-year follow-up, the patient remains playing at a competitive level, asymptomatic, with no reported reinjury. Adequate reporting of rehabilitation programs and PRP injection characterization is crucial for future research quality improvement and reproducibility.</p>","PeriodicalId":36847,"journal":{"name":"Journal of ISAKOS Joint Disorders & Orthopaedic Sports Medicine","volume":" ","pages":"100286"},"PeriodicalIF":2.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141427821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-01Epub Date: 2024-04-15DOI: 10.1016/j.jisako.2024.04.008
George Jacob, Kazunori Shimomura, Norimasa Nakamura
Stress fractures, a common overuse injury in physically active individuals, present a significant challenge for athletes and military personnel. Patients who sustain stress fractures have demanding training regimes where periods of rest and immobilisation have unacceptable negative consequences on sports goals and finances. Aside from being an overuse injury, there are various contributing risk factors that put certain individuals at risk of a stress fracture. The main two being nutritional deficiencies and hormonal variations, which have significant effects on bone metabolism and turnover. Historically, treatment of stress fractures focused on conservative strategies such as rest and immobilisation. Calcium and vitamin D deficiencies have been closely linked to stress fractures and so over time supplementation has also played a role in treatment. With the introduction of biologics into orthopaedics, newer treatment strategies have been applied to accelerate fracture healing and perhaps improve fracture callus quality. If such therapies can reduce time spent away from sport and activity, it would be ideal for treating stress fractures. This article aims to offer insights into the evolving landscape of stress fracture management. It investigates the pre-clinical evidence and available published clinical applications. Though fracture healing is well understood, the role of biologics for fracture healing is still indeterminate. Available literature for the use of biologic therapies in stress fractures are restricted and most reports have used biologics as a supplement to surgical fixation in subjects in studies that lack control groups. Randomised control trials have been proposed and registered by a few groups, with results awaited. Assessing individuals for risk factors, addressing hormonal imbalances and nutritional deficiencies seems like an effective approach to addressing the burden of stress fractures. We await better designed trials and studies to accurately determine the clinical benefit of adding biologics to the management of these injuries.
应力性骨折是体力活动者常见的过度劳损,对运动员和军人来说是一项重大挑战。发生应力性骨折的患者需要进行高强度的训练,休息和固定的时间会对运动目标和经济产生不可接受的负面影响。应力性骨折除了是一种过度劳损外,还有各种风险因素导致某些人面临应力性骨折的风险。其中最主要的两个因素是营养缺乏和荷尔蒙变化,它们对骨质代谢和新陈代谢有重大影响。从历史上看,应力性骨折的治疗主要采用保守疗法,如休息和固定。钙和维生素 D 的缺乏与应力性骨折密切相关,因此随着时间的推移,补充剂也在治疗中发挥了作用。随着生物制剂被引入骨科,更新的治疗策略被应用于加速骨折愈合,或许还能改善骨折胼胝的质量。如果这些疗法能缩短患者离开运动和活动的时间,那么它将成为治疗应力性骨折的理想选择。本文旨在深入探讨应力性骨折治疗的演变。文章对临床前证据和已发表的临床应用进行了研究。虽然人们对骨折愈合有了充分的认识,但生物制剂在骨折愈合中的作用仍不确定。关于应力性骨折使用生物制剂疗法的现有文献十分有限,大多数报告都是在缺乏对照组的研究中将生物制剂作为手术固定的补充。少数研究小组提出并登记了随机对照试验,结果尚待公布。评估个人风险因素、解决荷尔蒙失调和营养缺乏问题似乎是解决应力性骨折负担的有效方法。我们正等待设计更完善的试验和研究,以准确确定在这些损伤的治疗中添加生物制剂的临床益处。
{"title":"Biologic therapies in stress fractures: Current concepts.","authors":"George Jacob, Kazunori Shimomura, Norimasa Nakamura","doi":"10.1016/j.jisako.2024.04.008","DOIUrl":"10.1016/j.jisako.2024.04.008","url":null,"abstract":"<p><p>Stress fractures, a common overuse injury in physically active individuals, present a significant challenge for athletes and military personnel. Patients who sustain stress fractures have demanding training regimes where periods of rest and immobilisation have unacceptable negative consequences on sports goals and finances. Aside from being an overuse injury, there are various contributing risk factors that put certain individuals at risk of a stress fracture. The main two being nutritional deficiencies and hormonal variations, which have significant effects on bone metabolism and turnover. Historically, treatment of stress fractures focused on conservative strategies such as rest and immobilisation. Calcium and vitamin D deficiencies have been closely linked to stress fractures and so over time supplementation has also played a role in treatment. With the introduction of biologics into orthopaedics, newer treatment strategies have been applied to accelerate fracture healing and perhaps improve fracture callus quality. If such therapies can reduce time spent away from sport and activity, it would be ideal for treating stress fractures. This article aims to offer insights into the evolving landscape of stress fracture management. It investigates the pre-clinical evidence and available published clinical applications. Though fracture healing is well understood, the role of biologics for fracture healing is still indeterminate. Available literature for the use of biologic therapies in stress fractures are restricted and most reports have used biologics as a supplement to surgical fixation in subjects in studies that lack control groups. Randomised control trials have been proposed and registered by a few groups, with results awaited. Assessing individuals for risk factors, addressing hormonal imbalances and nutritional deficiencies seems like an effective approach to addressing the burden of stress fractures. We await better designed trials and studies to accurately determine the clinical benefit of adding biologics to the management of these injuries.</p>","PeriodicalId":36847,"journal":{"name":"Journal of ISAKOS Joint Disorders & Orthopaedic Sports Medicine","volume":" ","pages":"100256"},"PeriodicalIF":2.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140867450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-01Epub Date: 2024-06-06DOI: 10.1016/j.jisako.2024.06.001
Amit Meena, Riccardo D'Ambrosi, Luca Farinelli, Manish Attri, Ahmed Mabrouk, Norimasa Nakamura, Matthieu Ollivier, Sachin Tapasvi
<p><strong>Importance: </strong>Orthobiologics has seen a renaissance over the last decade as an adjunct therapy during osteotomy due to the limited inherent regenerative potential of damaged intraarticular tissues.</p><p><strong>Aim or objective: </strong>This systematic review aims to present the latest evidence regarding using orthobiologics with simultaneous high tibial osteotomy (HTO) for knee osteoarthritis. The results of this study may guide surgeons to improve their clinical results and clear the air regarding confusion over whether or not to add orthobiologics to HTO in clinical practice backed by scientific evidence.</p><p><strong>Evidence review: </strong>According to PRISMA guidelines a systematic search for relevant literature was performed in the PubMed (MEDLINE), Scopus, EMBASE, and Cochrane Library databases of all studies published in English from January 1990 to May 2023. The following search terms were entered into the title, abstract, and keyword fields: "knee" or "osteotomy" AND "valgus" or "varus" AND "regenerative medicine" or "PRP" or "mesenchymal stem cells" or "stem cells" or "BMAC" or "bone marrow" or "growth factors" or "umbilical cord blood-derived mesenchymal stem cell" or "stromal vascular fraction". The AMSTAR-2 checklist was used to confirm the quality of the systematic review. Randomised controlled trials (RCTs), prospective and retrospective comparative cohort studies, case-control studies, and case series were included. Studies that reported clinical outcomes in patients treated with knee osteotomy for varus/valgus knee with concomitant adjunction of regenerative treatment [Platelet-rich plasma (PRP), Adipose-derived stem cells (ADSC), Human Umbilical Cord Blood-Derived (HUCBD), Mesenchymal Stem Cells (MSC), bone marrow aspirate concentrate (BMAC), stromal vascular fraction (SVF)] were included. The outcome measures extracted from the studies were the KOOS score, Lysholm score, Subjective IKDC, WOMAC Score, KSS, Tegner, HSS, radiographic tibiofemoral angle, posterior tibial slope and complications. The current systematic review is registered in the PROSPERO Registry (CRD42023439379).</p><p><strong>Findings: </strong>Osteotomy for unicompartmental arthritis with adjunction of orthobiologics such as PRP, ADSC, HVCBD, MSC, BMAC, and SVF presents a consistent statistically significant clinical improvement compared to preoperative scores regardless of the treatment modality used and there were no notable complications associated with the use of these novel agents.</p><p><strong>Conclusions and relevance: </strong>Orthobiologics and knee osteotomies could improve outcomes in patients with knee osteoarthritis desiring Knee preservation surgeries. However, only a few studies are available on the topic to conclude anything with certainty, the patients included in the studies could not be disintegrated based on the grade of osteoarthritis (OA), type, dosage and frequency of administration of orthobiologic and type of ad
{"title":"Should I add orthobiologics to my knee osteotomy practice? A systematic review.","authors":"Amit Meena, Riccardo D'Ambrosi, Luca Farinelli, Manish Attri, Ahmed Mabrouk, Norimasa Nakamura, Matthieu Ollivier, Sachin Tapasvi","doi":"10.1016/j.jisako.2024.06.001","DOIUrl":"10.1016/j.jisako.2024.06.001","url":null,"abstract":"<p><strong>Importance: </strong>Orthobiologics has seen a renaissance over the last decade as an adjunct therapy during osteotomy due to the limited inherent regenerative potential of damaged intraarticular tissues.</p><p><strong>Aim or objective: </strong>This systematic review aims to present the latest evidence regarding using orthobiologics with simultaneous high tibial osteotomy (HTO) for knee osteoarthritis. The results of this study may guide surgeons to improve their clinical results and clear the air regarding confusion over whether or not to add orthobiologics to HTO in clinical practice backed by scientific evidence.</p><p><strong>Evidence review: </strong>According to PRISMA guidelines a systematic search for relevant literature was performed in the PubMed (MEDLINE), Scopus, EMBASE, and Cochrane Library databases of all studies published in English from January 1990 to May 2023. The following search terms were entered into the title, abstract, and keyword fields: \"knee\" or \"osteotomy\" AND \"valgus\" or \"varus\" AND \"regenerative medicine\" or \"PRP\" or \"mesenchymal stem cells\" or \"stem cells\" or \"BMAC\" or \"bone marrow\" or \"growth factors\" or \"umbilical cord blood-derived mesenchymal stem cell\" or \"stromal vascular fraction\". The AMSTAR-2 checklist was used to confirm the quality of the systematic review. Randomised controlled trials (RCTs), prospective and retrospective comparative cohort studies, case-control studies, and case series were included. Studies that reported clinical outcomes in patients treated with knee osteotomy for varus/valgus knee with concomitant adjunction of regenerative treatment [Platelet-rich plasma (PRP), Adipose-derived stem cells (ADSC), Human Umbilical Cord Blood-Derived (HUCBD), Mesenchymal Stem Cells (MSC), bone marrow aspirate concentrate (BMAC), stromal vascular fraction (SVF)] were included. The outcome measures extracted from the studies were the KOOS score, Lysholm score, Subjective IKDC, WOMAC Score, KSS, Tegner, HSS, radiographic tibiofemoral angle, posterior tibial slope and complications. The current systematic review is registered in the PROSPERO Registry (CRD42023439379).</p><p><strong>Findings: </strong>Osteotomy for unicompartmental arthritis with adjunction of orthobiologics such as PRP, ADSC, HVCBD, MSC, BMAC, and SVF presents a consistent statistically significant clinical improvement compared to preoperative scores regardless of the treatment modality used and there were no notable complications associated with the use of these novel agents.</p><p><strong>Conclusions and relevance: </strong>Orthobiologics and knee osteotomies could improve outcomes in patients with knee osteoarthritis desiring Knee preservation surgeries. However, only a few studies are available on the topic to conclude anything with certainty, the patients included in the studies could not be disintegrated based on the grade of osteoarthritis (OA), type, dosage and frequency of administration of orthobiologic and type of ad","PeriodicalId":36847,"journal":{"name":"Journal of ISAKOS Joint Disorders & Orthopaedic Sports Medicine","volume":" ","pages":"100282"},"PeriodicalIF":2.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141293809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: Sleep is an important determinant of quality of life. Sleep disturbance is concomitant with end-stage knee osteoarthritis for which total knee arthroplasty (TKA) is the most commonly done procedure. However, literature on this topic is lacking in terms of the impact of sleep quality on patient satisfaction after arthroplasty, especially the adverse associations of surgery on sleep quality. Improvement in sleep quality may be a necessary prerequisite for any effective rehabilitation program. In our study we aim to assess the changes in sleep quality after TKA, and how it affects patient satisfaction of TKA and other quality-of-life indicators, postoperatively.
Methods: Over a period of two years, 104 patients undergoing primary total knee arthroplasty were assessed prospectively using the Pittsburgh Sleep Quality Index (PSQI), Knee Society Score (KSS), Oxford Knee Score (OKS); preoperatively and postoperatively at 3 months, 6 months, and 1 year. Obesity and diabetes status were also included in the analyses.
Results: Preoperatively, most patients exhibited poor sleep quality (mean PSQI score 9.23 (Standard deviation (SD) = 3.03), which subsequently improved after surgery. Immediately after surgery, there was an initial worsening in the PSQI scores until 6 weeks (12.58 (SD = 3.59)). However, at 1 year, there was a statistically significant improvement to a mean of 5.69 (SD = 1.91). The mean Visual Analogue Scale (VAS) score showed a statistically significant decrease from 7.26 (SD = 1.90) pre-operatively to 1.80 (SD = 1.37) at 1 year postoperatively (p < 0.001). The mean OKS showed a statistically significant increase from preoperative 18.15 to 33.81 at 1 year and the composite KSS increased from 36.22 preoperative to 87.09 at 1 year (p < 0.001). Improvement in sleep was observed for 61% of non-obese patients while obese patients did not observe any improvement in sleep. Only 8% of diabetics showed improved sleep compared to 55% of non-diabetics.
Conclusions: We observed an overall improvement in sleep quality after total knee arthroplasty. However, there was an initial stage of sleep disturbance immediately postoperatively. Obesity and diabetes may lower the chances of achieving optimal improvements in both functional and sleep outcomes.
{"title":"Sleep quality improves after total knee arthroplasty: Addressing early disturbance and risk factors.","authors":"Nirali Mehta, Parag Sancheti, Ashok Shyam, Kailash Patil, Sunny Gugale, Nisar Obaid, Yogesh Sisodia, Sahil Sanghavi","doi":"10.1016/j.jisako.2024.100373","DOIUrl":"10.1016/j.jisako.2024.100373","url":null,"abstract":"<p><strong>Objectives: </strong>Sleep is an important determinant of quality of life. Sleep disturbance is concomitant with end-stage knee osteoarthritis for which total knee arthroplasty (TKA) is the most commonly done procedure. However, literature on this topic is lacking in terms of the impact of sleep quality on patient satisfaction after arthroplasty, especially the adverse associations of surgery on sleep quality. Improvement in sleep quality may be a necessary prerequisite for any effective rehabilitation program. In our study we aim to assess the changes in sleep quality after TKA, and how it affects patient satisfaction of TKA and other quality-of-life indicators, postoperatively.</p><p><strong>Methods: </strong>Over a period of two years, 104 patients undergoing primary total knee arthroplasty were assessed prospectively using the Pittsburgh Sleep Quality Index (PSQI), Knee Society Score (KSS), Oxford Knee Score (OKS); preoperatively and postoperatively at 3 months, 6 months, and 1 year. Obesity and diabetes status were also included in the analyses.</p><p><strong>Results: </strong>Preoperatively, most patients exhibited poor sleep quality (mean PSQI score 9.23 (Standard deviation (SD) = 3.03), which subsequently improved after surgery. Immediately after surgery, there was an initial worsening in the PSQI scores until 6 weeks (12.58 (SD = 3.59)). However, at 1 year, there was a statistically significant improvement to a mean of 5.69 (SD = 1.91). The mean Visual Analogue Scale (VAS) score showed a statistically significant decrease from 7.26 (SD = 1.90) pre-operatively to 1.80 (SD = 1.37) at 1 year postoperatively (p < 0.001). The mean OKS showed a statistically significant increase from preoperative 18.15 to 33.81 at 1 year and the composite KSS increased from 36.22 preoperative to 87.09 at 1 year (p < 0.001). Improvement in sleep was observed for 61% of non-obese patients while obese patients did not observe any improvement in sleep. Only 8% of diabetics showed improved sleep compared to 55% of non-diabetics.</p><p><strong>Conclusions: </strong>We observed an overall improvement in sleep quality after total knee arthroplasty. However, there was an initial stage of sleep disturbance immediately postoperatively. Obesity and diabetes may lower the chances of achieving optimal improvements in both functional and sleep outcomes.</p><p><strong>Level of evidence: </strong>Level III.</p>","PeriodicalId":36847,"journal":{"name":"Journal of ISAKOS Joint Disorders & Orthopaedic Sports Medicine","volume":" ","pages":"100373"},"PeriodicalIF":2.7,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142773178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-30DOI: 10.1016/j.jisako.2024.100369
Claudio Legnani, Matteo Del Re, Giuseppe M Peretti, Vittorio Macchi, Enrico Borgo, Alberto Ventura
Objectives: The purposes of this study were to (1) prospectively evaluate clinical and functional outcomes of athletes following anterior cruciate ligament (ACL) reconstruction up to 12 months after surgery, (2) to identify the correlations between functional and subjective tests, and (3) to determine which factors influence patients' capability to resume sports at pre-injury level.
Methods: Patients who underwent ACL reconstruction using doubled autologous hamstring graft were prospectively assessed pre-operatively, 6, and 12 months after surgery using International Knee Documentation Committee (IKDC) Subjective Knee Form, Tegner activity level, and ACL-Return to Sport after Injury (ACL-RSI) scale. Jumping ability was instrumentally assessed using a test battery including bipodalic squat jump (SJ), bipodalic countermovement jump (CMJ), monopodalic CMJ, and monopodalic side-hop test.
Results: Thirty-three patients were available for clinical evaluation at 12-months follow-up. Average age was 34.0 years (SD 11.5, range 19-50). Male/female ratio was 31:2. Mean overall IKDC, and ACL-RSI scores increased from 52.5 to 47.1 preoperatively, to 89.9 (SD: 12.2, range 36.8-100) and 81.3 (SD 21.7, range 10-98.3), respectively at last follow-up (p < 0.001). Monopodalic jump tests showed improvements at 12-month evaluation compared to 6-month follow-up (p < 0.01). No statistically significant correlation was reported for ACL-RSI and jump limb symmetry index (LSI) (p = 0.08 vs. CMJ; p = 0.07 vs. side-hop test). No differences were observed in terms of jump LSI between patients who returned to pre-injury activity level and those who did not (p = 0.11 for CMJ, p = 0.09 for side-hop test). A significantly higher IKDC score at 6 months was observed in patients who did not return to pre-injury levels (p = 0.009). Patients who did not return to pre-injury activity reported lower ACL-RSI scores at 12-months follow-up (p = 0.007).
Conclusions: One year after ACL reconstruction, an improvement in jumping ability was observed, while a persistence of lower limbs asymmetries when performing jump tests was noted at 6-months follow-up. The ability to perform vertical jumps was not influenced by psychological outcomes 12 months following surgery. Higher values of subjective knee score and psychological readiness weakly correlated to return to sport at preinjury level, while no correlation was reported concerning jumping performance.
{"title":"Return to sport at the pre-injury level following anterior cruciate ligament reconstruction is influenced by patients' perceived knee status and psychological readiness, and does not correlate with functional ability.","authors":"Claudio Legnani, Matteo Del Re, Giuseppe M Peretti, Vittorio Macchi, Enrico Borgo, Alberto Ventura","doi":"10.1016/j.jisako.2024.100369","DOIUrl":"10.1016/j.jisako.2024.100369","url":null,"abstract":"<p><strong>Objectives: </strong>The purposes of this study were to (1) prospectively evaluate clinical and functional outcomes of athletes following anterior cruciate ligament (ACL) reconstruction up to 12 months after surgery, (2) to identify the correlations between functional and subjective tests, and (3) to determine which factors influence patients' capability to resume sports at pre-injury level.</p><p><strong>Methods: </strong>Patients who underwent ACL reconstruction using doubled autologous hamstring graft were prospectively assessed pre-operatively, 6, and 12 months after surgery using International Knee Documentation Committee (IKDC) Subjective Knee Form, Tegner activity level, and ACL-Return to Sport after Injury (ACL-RSI) scale. Jumping ability was instrumentally assessed using a test battery including bipodalic squat jump (SJ), bipodalic countermovement jump (CMJ), monopodalic CMJ, and monopodalic side-hop test.</p><p><strong>Results: </strong>Thirty-three patients were available for clinical evaluation at 12-months follow-up. Average age was 34.0 years (SD 11.5, range 19-50). Male/female ratio was 31:2. Mean overall IKDC, and ACL-RSI scores increased from 52.5 to 47.1 preoperatively, to 89.9 (SD: 12.2, range 36.8-100) and 81.3 (SD 21.7, range 10-98.3), respectively at last follow-up (p < 0.001). Monopodalic jump tests showed improvements at 12-month evaluation compared to 6-month follow-up (p < 0.01). No statistically significant correlation was reported for ACL-RSI and jump limb symmetry index (LSI) (p = 0.08 vs. CMJ; p = 0.07 vs. side-hop test). No differences were observed in terms of jump LSI between patients who returned to pre-injury activity level and those who did not (p = 0.11 for CMJ, p = 0.09 for side-hop test). A significantly higher IKDC score at 6 months was observed in patients who did not return to pre-injury levels (p = 0.009). Patients who did not return to pre-injury activity reported lower ACL-RSI scores at 12-months follow-up (p = 0.007).</p><p><strong>Conclusions: </strong>One year after ACL reconstruction, an improvement in jumping ability was observed, while a persistence of lower limbs asymmetries when performing jump tests was noted at 6-months follow-up. The ability to perform vertical jumps was not influenced by psychological outcomes 12 months following surgery. Higher values of subjective knee score and psychological readiness weakly correlated to return to sport at preinjury level, while no correlation was reported concerning jumping performance.</p>","PeriodicalId":36847,"journal":{"name":"Journal of ISAKOS Joint Disorders & Orthopaedic Sports Medicine","volume":" ","pages":"100369"},"PeriodicalIF":2.7,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142773173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-24DOI: 10.1016/j.jisako.2024.100368
Bandar S Alrashedan, Sarah Remedios, Ivan Wong
Objectives: This study aims to evaluate the outcomes of patients following surgery diagnosed with femoroacetabular impingement syndrome (FAIS) who also experience low back and other joint pain compared to those with isolated hip pain.
Methods: This is a retrospective cohort study of patients diagnosed with FAIS, with or without other joint pain, treated with hip arthroscopy from 2016 to 2020. Excluded cases were patients who had significant arthritis, irreparable labral tear requiring reconstruction, or were lost follow-up. Analysis was carried out in two ways, the first was according to the musculoskeletal morbidity (MSKM) scheme where patients were stratified into four different groups, and the second was according to the presence of any other joint or back pain (MSKM 2-4) compared to hip pain only (MSKM 1). Demographic data was analyzed between the groups. International Hip Outcome Tool 33 (iHOT-33) and Hip Outcome Score (HOS) were used as the primary and secondary outcome measures pre-operatively and a minimum of two years postoperatively.
Results: A total of 131 patients were included in the study with 37 % males and 63 % females. Age (years) and body mass index (kg/m2) were similar between groups, whereas a statistically greater number of male participants were seen in the hip pain only group (MSKM 1). Pre-operatively, patients with isolated hip pain (MSKM 1), had a higher iHOT-33 scores (p < 0.05), but no statistically significant differences were observed postoperatively between the groups. All groups demonstrated a statistically significant improvement in iHOT-33 and HOS scores postoperatively compared to pre-operatively (p < 0.05), with 76 % meeting the threshold for minimum clinically important difference.
Conclusion: Patient-reported outcomes following hip arthroscopy for FAIS were significantly greater postoperatively for all patients, despite the presence of other joint or back pain. This study can assist in driving patient expectations following hip arthroscopy for FAIS.
{"title":"Patients with associated spine or other major joint pain have equivalent outcomes to patients with isolated hip pain after hip arthroscopy.","authors":"Bandar S Alrashedan, Sarah Remedios, Ivan Wong","doi":"10.1016/j.jisako.2024.100368","DOIUrl":"10.1016/j.jisako.2024.100368","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to evaluate the outcomes of patients following surgery diagnosed with femoroacetabular impingement syndrome (FAIS) who also experience low back and other joint pain compared to those with isolated hip pain.</p><p><strong>Methods: </strong>This is a retrospective cohort study of patients diagnosed with FAIS, with or without other joint pain, treated with hip arthroscopy from 2016 to 2020. Excluded cases were patients who had significant arthritis, irreparable labral tear requiring reconstruction, or were lost follow-up. Analysis was carried out in two ways, the first was according to the musculoskeletal morbidity (MSKM) scheme where patients were stratified into four different groups, and the second was according to the presence of any other joint or back pain (MSKM 2-4) compared to hip pain only (MSKM 1). Demographic data was analyzed between the groups. International Hip Outcome Tool 33 (iHOT-33) and Hip Outcome Score (HOS) were used as the primary and secondary outcome measures pre-operatively and a minimum of two years postoperatively.</p><p><strong>Results: </strong>A total of 131 patients were included in the study with 37 % males and 63 % females. Age (years) and body mass index (kg/m<sup>2</sup>) were similar between groups, whereas a statistically greater number of male participants were seen in the hip pain only group (MSKM 1). Pre-operatively, patients with isolated hip pain (MSKM 1), had a higher iHOT-33 scores (p < 0.05), but no statistically significant differences were observed postoperatively between the groups. All groups demonstrated a statistically significant improvement in iHOT-33 and HOS scores postoperatively compared to pre-operatively (p < 0.05), with 76 % meeting the threshold for minimum clinically important difference.</p><p><strong>Conclusion: </strong>Patient-reported outcomes following hip arthroscopy for FAIS were significantly greater postoperatively for all patients, despite the presence of other joint or back pain. This study can assist in driving patient expectations following hip arthroscopy for FAIS.</p><p><strong>Level of evidence: </strong>IV.</p>","PeriodicalId":36847,"journal":{"name":"Journal of ISAKOS Joint Disorders & Orthopaedic Sports Medicine","volume":" ","pages":"100368"},"PeriodicalIF":2.7,"publicationDate":"2024-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142717263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-22DOI: 10.1016/j.jisako.2024.100367
Elliott W Cole, Katherine E Bach, Jeffrey J Theismann, Luke L Sang, Zaim Chaudhary, Nirav K Pandya, Brian T Feeley
Introduction: Anterior cruciate ligament (ACL) injuries and ACL reconstruction (ACLR) surgery are very common. Patients increasingly use social media platforms like YouTube to find healthcare information to help them make medical decisions. The purpose of this study was to evaluate the quality of YouTube videos providing information about ACL injuries and ACL surgery.
Methods: The most-viewed YouTube videos for ACL-associated search terms were reviewed for inclusion and assessed by two authors using four video quality assessment tools: the Journal of American Medical Association benchmark (JAMA) (0-4), Global Quality Score (GQS) (1-5), modified DISCERN (mod-DISCERN) (0-5), and YouTube ACL Specific Score (the score) (0-25). Intraclass correlation coefficients (ICCs) were calculated to determine interrater reliability. Unpaired t-tests were used for comparisons between groups and linear regressions to identify associations.
Results: There were 45 videos that met the inclusion criteria. Overall, 31.1% of videos reported an academic affiliation, and 53.3% listed an MD as the lead author. The mean JAMA score was 2.8, GQS 3.2, mod-DISCERN 2.6, and overall the score 5.9. There was good interobserver agreement across all quality tools (ICC>0.75). Videos with an MD lead author had significantly higher JAMA (p < 0.001) and GQS (p < 0.01) scores than those led by non-physicians. Videos with academic affiliations had significantly higher JAMA (p < 0.001), GQS (p < 0.01), mod-DISCERN (p < 0.01), and the score Management Domain (p = 0.04) scores.
Conclusion: Among the most-viewed YouTube videos related to ACL injuries and ACL surgery, physician-led and academically affiliated videos provided higher quality educational information compared to other sources, however, the overall quality of content provided is low.
{"title":"Physician-led YouTube videos related to anterior cruciate ligament injuries provide higher-quality educational content compared to other sources.","authors":"Elliott W Cole, Katherine E Bach, Jeffrey J Theismann, Luke L Sang, Zaim Chaudhary, Nirav K Pandya, Brian T Feeley","doi":"10.1016/j.jisako.2024.100367","DOIUrl":"10.1016/j.jisako.2024.100367","url":null,"abstract":"<p><strong>Introduction: </strong>Anterior cruciate ligament (ACL) injuries and ACL reconstruction (ACLR) surgery are very common. Patients increasingly use social media platforms like YouTube to find healthcare information to help them make medical decisions. The purpose of this study was to evaluate the quality of YouTube videos providing information about ACL injuries and ACL surgery.</p><p><strong>Methods: </strong>The most-viewed YouTube videos for ACL-associated search terms were reviewed for inclusion and assessed by two authors using four video quality assessment tools: the Journal of American Medical Association benchmark (JAMA) (0-4), Global Quality Score (GQS) (1-5), modified DISCERN (mod-DISCERN) (0-5), and YouTube ACL Specific Score (the score) (0-25). Intraclass correlation coefficients (ICCs) were calculated to determine interrater reliability. Unpaired t-tests were used for comparisons between groups and linear regressions to identify associations.</p><p><strong>Results: </strong>There were 45 videos that met the inclusion criteria. Overall, 31.1% of videos reported an academic affiliation, and 53.3% listed an MD as the lead author. The mean JAMA score was 2.8, GQS 3.2, mod-DISCERN 2.6, and overall the score 5.9. There was good interobserver agreement across all quality tools (ICC>0.75). Videos with an MD lead author had significantly higher JAMA (p < 0.001) and GQS (p < 0.01) scores than those led by non-physicians. Videos with academic affiliations had significantly higher JAMA (p < 0.001), GQS (p < 0.01), mod-DISCERN (p < 0.01), and the score Management Domain (p = 0.04) scores.</p><p><strong>Conclusion: </strong>Among the most-viewed YouTube videos related to ACL injuries and ACL surgery, physician-led and academically affiliated videos provided higher quality educational information compared to other sources, however, the overall quality of content provided is low.</p><p><strong>Level of evidence: </strong>Level IV.</p>","PeriodicalId":36847,"journal":{"name":"Journal of ISAKOS Joint Disorders & Orthopaedic Sports Medicine","volume":" ","pages":"100367"},"PeriodicalIF":2.7,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142711152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-22DOI: 10.1016/j.jisako.2024.100366
Betina B Hinckel, Pietro Conte, Justin T Smith, Norimasa Nakamura, Elizaveta Kon
Cartilage lesions around the knee are common injuries in the orthopedic practice. The spontaneous healing capacity of the articular cartilage is limited, and therefore surgical intervention may be necessary. The goal is to improve patients' symptoms, articular functionality, and potentially delay the progression of knee osteoarthritis. Extensive knowledge is available regarding the efficacy of cartilage restoration procedures for tibiofemoral chondral and osteochondral lesions; however, evidence on patellofemoral surgery remains more limited and controversial. The complex biomechanics and morphology of the patellofemoral joint represents a challenge in the setting of knee cartilage surgery and, as a result, inferior outcomes have been reported when compared to treatment of condylar lesions. Furthermore, patellofemoral cartilage restoration can be combined with procedures such as a tibial tuberosity osteotomy and/or other realigning osteotomies when pathological deformities are present. Finally, when the aforementioned strategies fail or when severe osteoarthritis develops, and preservation procedures are contraindicated, arthroplasty and other options can be considered. This State of the Art review aims to critically examine the current concepts of conservative and surgical treatment of patellofemoral cartilage lesions, reporting the latest clinical evidence and describing potential future perspectives in this field.
{"title":"Patellofemoral joint part 3 (Patellofemoral cartilage treatment): State of the art.","authors":"Betina B Hinckel, Pietro Conte, Justin T Smith, Norimasa Nakamura, Elizaveta Kon","doi":"10.1016/j.jisako.2024.100366","DOIUrl":"10.1016/j.jisako.2024.100366","url":null,"abstract":"<p><p>Cartilage lesions around the knee are common injuries in the orthopedic practice. The spontaneous healing capacity of the articular cartilage is limited, and therefore surgical intervention may be necessary. The goal is to improve patients' symptoms, articular functionality, and potentially delay the progression of knee osteoarthritis. Extensive knowledge is available regarding the efficacy of cartilage restoration procedures for tibiofemoral chondral and osteochondral lesions; however, evidence on patellofemoral surgery remains more limited and controversial. The complex biomechanics and morphology of the patellofemoral joint represents a challenge in the setting of knee cartilage surgery and, as a result, inferior outcomes have been reported when compared to treatment of condylar lesions. Furthermore, patellofemoral cartilage restoration can be combined with procedures such as a tibial tuberosity osteotomy and/or other realigning osteotomies when pathological deformities are present. Finally, when the aforementioned strategies fail or when severe osteoarthritis develops, and preservation procedures are contraindicated, arthroplasty and other options can be considered. This State of the Art review aims to critically examine the current concepts of conservative and surgical treatment of patellofemoral cartilage lesions, reporting the latest clinical evidence and describing potential future perspectives in this field.</p>","PeriodicalId":36847,"journal":{"name":"Journal of ISAKOS Joint Disorders & Orthopaedic Sports Medicine","volume":" ","pages":"100366"},"PeriodicalIF":2.7,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142695920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}