Pub Date : 2025-04-01DOI: 10.1016/j.rccl.2025.01.006
Rocío García-Orta , Miguel Morales García , Eduardo Moreno Escobar
{"title":"La impresión tridimensional a partir de la ecografía transtorácica en las cardiopatías congénitas","authors":"Rocío García-Orta , Miguel Morales García , Eduardo Moreno Escobar","doi":"10.1016/j.rccl.2025.01.006","DOIUrl":"10.1016/j.rccl.2025.01.006","url":null,"abstract":"","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"60 2","pages":"Pages 74-75"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143858814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-04-01DOI: 10.1016/j.rccl.2024.12.003
Carlos Alcántara Noguez , Alejandra Contreras-Ramos , Maria Esther Lazcano Melo , Karen Janeth Zúñiga Sánchez , Sergio Ruiz , Patricia Romero Cárdenas , Alejandro Bolio Cerdán , Juan Manuel Vera Canelo
Introduction and objectives
The 22q11.2 deletion syndrome (22q11.2 DS), known as DiGeorge syndrome, is phenotypically associated with conotruncal heart defects. The aim of this review was to evaluate mortality in pediatric patients with corrected conotruncal defects.
Methods
A literature search was conducted in the databases PubMed, ScienceDirect, Google Scholar, and Redalyc databases, covering the last 10 years. Original articles with pediatric population diagnosed with 22q11.2 DS and conotruncal congenital heart defects were included. A statistical analysis of 5 studies was performed, evaluating the odds ratio (OR), 95% confidence intervals (95%CI), and statistical significance using the chi-square test for each exposure variable. The ROBINS-E tool was used to assess the risk of bias.
Results
A total of 18 articles were collected, including a total population of 10 993 patients (3225 with 22q11.2 DS). The most frequent cardiac defect was tetralogy of Fallot (n = 655). The most common intraoperative complications were arrhythmias, and the most common postoperative complications were infections. Mortality in patients with 22q11.2 DS was assessed. The OR was 0.74 (95%CI, 0.38-1.45; P = .38). Heterogeneity test yielded an I2 = 66%.
Conclusions
22q11.2 DS is not associated with post-surgical mortality in patients treated for conotruncal congenital heart defects.
{"title":"Impacto del síndrome de deleción 22q11.2 en la mortalidad de los pacientes pediátricos con defectos conotruncales corregidos","authors":"Carlos Alcántara Noguez , Alejandra Contreras-Ramos , Maria Esther Lazcano Melo , Karen Janeth Zúñiga Sánchez , Sergio Ruiz , Patricia Romero Cárdenas , Alejandro Bolio Cerdán , Juan Manuel Vera Canelo","doi":"10.1016/j.rccl.2024.12.003","DOIUrl":"10.1016/j.rccl.2024.12.003","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>The 22q11.2 deletion syndrome (22q11.2 DS), known as DiGeorge syndrome, is phenotypically associated with conotruncal heart defects. The aim of this review was to evaluate mortality in pediatric patients with corrected conotruncal defects.</div></div><div><h3>Methods</h3><div>A literature search was conducted in the databases PubMed, ScienceDirect, Google Scholar, and Redalyc databases, covering the last 10 years. Original articles with pediatric population diagnosed with 22q11.2 DS and conotruncal congenital heart defects were included. A statistical analysis of 5 studies was performed, evaluating the odds ratio (OR), 95% confidence intervals (95%CI), and statistical significance using the chi-square test for each exposure variable. The ROBINS-E tool was used to assess the risk of bias.</div></div><div><h3>Results</h3><div>A total of 18 articles were collected, including a total population of 10<!--> <!-->993 patients (3225 with 22q11.2 DS). The most frequent cardiac defect was tetralogy of Fallot (n<!--> <!-->=<!--> <!-->655). The most common intraoperative complications were arrhythmias, and the most common postoperative complications were infections. Mortality in patients with 22q11.2 DS was assessed. The OR was 0.74 (95%CI, 0.38-1.45; <em>P<!--> </em>=<!--> <!-->.38). Heterogeneity test yielded an I<sup>2</sup> <!-->=<!--> <!-->66%.</div></div><div><h3>Conclusions</h3><div>22q11.2 DS is not associated with post-surgical mortality in patients treated for conotruncal congenital heart defects.</div></div>","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"60 2","pages":"Pages 97-105"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143858865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-04-01DOI: 10.1016/j.rccl.2024.10.009
Jon Zubiaur , Víctor Fernández Lobo , Gonzalo Martín Gorria , Luis Javier Ruiz Guerrero
{"title":"Pheochromocytoma as a trigger of miocarditis in arrhythmogenic cardiomyopathy","authors":"Jon Zubiaur , Víctor Fernández Lobo , Gonzalo Martín Gorria , Luis Javier Ruiz Guerrero","doi":"10.1016/j.rccl.2024.10.009","DOIUrl":"10.1016/j.rccl.2024.10.009","url":null,"abstract":"","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"60 2","pages":"Pages 155-157"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143858867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-04-01DOI: 10.1016/j.rccl.2024.10.012
José Carlos López-Clemente , Laura Fuertes-Kenneally , José Abellán Huerta , Federico Soria Arcos , Javier González-López , Rosario Mármol Lozano , Juan Antonio Castillo Moreno
Introduction and objectives
Heart failure (HF) poses a significant global health burden. Patients with HF experience reduced exercise tolerance, greatly affecting their quality of life. While creatine monohydrate (CM) improves functional capacity in healthy individuals, its effects in HF patients remain unexplored.
Methods
We conducted an exploratory, prospective, single center, open-label study evaluating the efficacy and safety of 5 g/day CM during 3 months in patients with HF and reduced ejection fraction. Outcomes included functional capacity, health-related quality of life (HRQoL), echocardiographic and laboratory parameters at 3-months and HF decompensations and mortality at 1-year.
Results
A total of 43 patients participated (60.73 ± 11.73 years; 30.43% females). The intervention was safe. Creatinine increased and glomerular filtration rate declined at 3 months but normalized after discontinuing CM. We observed a statistically significant increase in the 6-minute walk test (48.69 ± 32.76; P = .005), a reduction in Borg scale exertion (−1.57 ± −1.73 points; P < .01), and decreased heart rate increment during exercise (−2.43 ± −8.66 bpm; P = .04). HRQoL improved significantly (4.08 ± 12.29 points; P = .03). No changes were found in echocardiographic parameters, HF decompensations, or mortality.
Conclusions
CM supplementation in patients with HF and reduced ejection fraction is safe and could improve functional capacity and HRQoL. Further research is warranted to confirm our results.
{"title":"Efficacy and safety of creatine supplementation in patients with heart failure and reduced ejection fraction: a pilot study","authors":"José Carlos López-Clemente , Laura Fuertes-Kenneally , José Abellán Huerta , Federico Soria Arcos , Javier González-López , Rosario Mármol Lozano , Juan Antonio Castillo Moreno","doi":"10.1016/j.rccl.2024.10.012","DOIUrl":"10.1016/j.rccl.2024.10.012","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Heart failure (HF) poses a significant global health burden. Patients with HF experience reduced exercise tolerance, greatly affecting their quality of life. While creatine monohydrate (CM) improves functional capacity in healthy individuals, its effects in HF patients remain unexplored.</div></div><div><h3>Methods</h3><div>We conducted an exploratory, prospective, single center, open-label study evaluating the efficacy and safety of 5<!--> <!-->g/day CM during 3 months in patients with HF and reduced ejection fraction. Outcomes included functional capacity, health-related quality of life (HRQoL), echocardiographic and laboratory parameters at 3-months and HF decompensations and mortality at 1-year.</div></div><div><h3>Results</h3><div>A total of 43 patients participated (60.73<!--> <!-->±<!--> <!-->11.73<!--> <!-->years; 30.43% females). The intervention was safe. Creatinine increased and glomerular filtration rate declined at 3 months but normalized after discontinuing CM. We observed a statistically significant increase in the 6-minute walk test (48.69<!--> <!-->±<!--> <!-->32.76; <em>P</em> <!-->=<!--> <!-->.005), a reduction in Borg scale exertion (−1.57<!--> <!-->±<!--> <!-->−1.73 points; <em>P</em> <!--><<!--> <!-->.01), and decreased heart rate increment during exercise (−2.43<!--> <!-->±<!--> <!-->−8.66<!--> <!-->bpm; <em>P</em> <!-->=<!--> <!-->.04). HRQoL improved significantly (4.08<!--> <!-->±<!--> <!-->12.29 points; <em>P</em> <!-->=<!--> <!-->.03). No changes were found in echocardiographic parameters, HF decompensations, or mortality.</div></div><div><h3>Conclusions</h3><div>CM supplementation in patients with HF and reduced ejection fraction is safe and could improve functional capacity and HRQoL. Further research is warranted to confirm our results.</div></div>","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"60 2","pages":"Pages 76-86"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143858971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-04-01DOI: 10.1016/j.rccl.2024.12.002
Luis Antonio Jiménez Salinas , Clara A. Vázquez Antona , Tomás Efraín Sánchez Pérez , Juan Carlos Barrera de la Torre , Ana Laura Trujeque Ruiz
Introduction and objectives
Three-dimensional (3D) printing applied to cardiology has demonstrated its usefulness, supporting the planning of surgical and interventional procedures, especially for congenital heart disease. Although printed models have been documented using transesophageal echocardiography images, this technique has limitations in small pediatric patients. The objective was to determine the feasibility and accuracy of digital and printed 3D models obtained from the acquisition of transthoracic images in pediatric patients with ventricular septal defect.
Methods
Five pediatric patients with different locations of the defect were studied. Echocardiographic data were extracted, images processed, segmentation conducted, designs optimized, and models printed; the morphology, diameters of the defect, and their spatial relationships were analyzed.
Results
The correlation between the measurements obtained from 3D echocardiography and the digital 3D models and printed models was high (correlation coefficients of 0.953 and 0.952, respectively). The mean absolute difference between the values obtained by 3D echocardiography and the digital 3D models was 0.064 mm, while the mean absolute difference between the values obtained by 3D echocardiography and the printed models was 0.644 mm. There were no statistically significant differences between echocardiography and the models.
Conclusions
3D digital and printed models obtained from transthoracic echocardiographic data in pediatric patients are technically feasible and accurately reflect the morphology, spatial relationships, and dimensions of the different types of ventricular septal defect. However, the visualization of the models may vary according to the location of the defect, with muscle defects being easier to represent compared to perimembranous defects.
{"title":"Factibilidad y precisión de la impresión 3D a través de ecocardiografía transtorácica 3D en pacientes pediátricos","authors":"Luis Antonio Jiménez Salinas , Clara A. Vázquez Antona , Tomás Efraín Sánchez Pérez , Juan Carlos Barrera de la Torre , Ana Laura Trujeque Ruiz","doi":"10.1016/j.rccl.2024.12.002","DOIUrl":"10.1016/j.rccl.2024.12.002","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Three-dimensional (3D) printing applied to cardiology has demonstrated its usefulness, supporting the planning of surgical and interventional procedures, especially for congenital heart disease. Although printed models have been documented using transesophageal echocardiography images, this technique has limitations in small pediatric patients. The objective was to determine the feasibility and accuracy of digital and printed 3D models obtained from the acquisition of transthoracic images in pediatric patients with ventricular septal defect.</div></div><div><h3>Methods</h3><div>Five pediatric patients with different locations of the defect were studied. Echocardiographic data were extracted, images processed, segmentation conducted, designs optimized, and models printed; the morphology, diameters of the defect, and their spatial relationships were analyzed.</div></div><div><h3>Results</h3><div>The correlation between the measurements obtained from 3D echocardiography and the digital 3D models and printed models was high (correlation coefficients of 0.953 and 0.952, respectively). The mean absolute difference between the values obtained by 3D echocardiography and the digital 3D models was 0.064<!--> <!-->mm, while the mean absolute difference between the values obtained by 3D echocardiography and the printed models was 0.644<!--> <!-->mm. There were no statistically significant differences between echocardiography and the models.</div></div><div><h3>Conclusions</h3><div>3D digital and printed models obtained from transthoracic echocardiographic data in pediatric patients are technically feasible and accurately reflect the morphology, spatial relationships, and dimensions of the different types of ventricular septal defect. However, the visualization of the models may vary according to the location of the defect, with muscle defects being easier to represent compared to perimembranous defects.</div></div>","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"60 2","pages":"Pages 87-96"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143858864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-04-01DOI: 10.1016/j.rccl.2024.11.003
José M. de la Torre-Hernández , Guillermo Aldama-López , Rut Andrea , Miguel Corbí-Pascual , Alberto Cordero , María Rosa Fernández Olmo , Xavier García-Moll , Antonio García Quintana , Arantxa Matalí , Miriam Sandín Rollán , Xoana Taboada , Ana Viana Tejedor , Sergio Raposeiras-Roubín
In recent years, efforts in the care of acute myocardial infarction (AMI) have focused on ensuring a rapid response during the acute phase. However, follow-up after hospitalization is essential for adequate recovery and the prevention of future complications. Heart failure following an infarction is a common complication that implies a worse prognosis and a high rate of readmission, increasing the risk of death both in its early phase and in the long term. The Myocardial infarction and heart failure model (MIMIC) project analyzed patient care after an AMI in different healthcare models, with the aim of identifying recommendations for improvement and best practices that contribute to generalizing optimal care models after an AMI, to achieve a better prognosis, a higher quality of life, and a reduction in healthcare costs.
{"title":"Recomendaciones para la optimización de la atención a los pacientes tras infarto agudo de miocardio. Proyecto MIMIC","authors":"José M. de la Torre-Hernández , Guillermo Aldama-López , Rut Andrea , Miguel Corbí-Pascual , Alberto Cordero , María Rosa Fernández Olmo , Xavier García-Moll , Antonio García Quintana , Arantxa Matalí , Miriam Sandín Rollán , Xoana Taboada , Ana Viana Tejedor , Sergio Raposeiras-Roubín","doi":"10.1016/j.rccl.2024.11.003","DOIUrl":"10.1016/j.rccl.2024.11.003","url":null,"abstract":"<div><div>In recent years, efforts in the care of acute myocardial infarction (AMI) have focused on ensuring a rapid response during the acute phase. However, follow-up after hospitalization is essential for adequate recovery and the prevention of future complications. Heart failure following an infarction is a common complication that implies a worse prognosis and a high rate of readmission, increasing the risk of death both in its early phase and in the long term. The Myocardial infarction and heart failure model (MIMIC) project analyzed patient care after an AMI in different healthcare models, with the aim of identifying recommendations for improvement and best practices that contribute to generalizing optimal care models after an AMI, to achieve a better prognosis, a higher quality of life, and a reduction in healthcare costs.</div></div>","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"60 2","pages":"Pages 127-138"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143858871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}