REC: CardioClinics最新文献

英文中文

Efficacy and safety of creatine supplementation in patients with heart failure and reduced ejection fraction: a pilot study 补充肌酸对心力衰竭和射血分数降低患者的疗效和安全性：一项初步研究

Q4 Medicine

REC: CardioClinics

Pub Date : 2025-04-01 DOI: 10.1016/j.rccl.2024.10.012

José Carlos López-Clemente , Laura Fuertes-Kenneally , José Abellán Huerta , Federico Soria Arcos , Javier González-López , Rosario Mármol Lozano , Juan Antonio Castillo Moreno

Introduction and objectives

Heart failure (HF) poses a significant global health burden. Patients with HF experience reduced exercise tolerance, greatly affecting their quality of life. While creatine monohydrate (CM) improves functional capacity in healthy individuals, its effects in HF patients remain unexplored.

Methods

We conducted an exploratory, prospective, single center, open-label study evaluating the efficacy and safety of 5 g/day CM during 3 months in patients with HF and reduced ejection fraction. Outcomes included functional capacity, health-related quality of life (HRQoL), echocardiographic and laboratory parameters at 3-months and HF decompensations and mortality at 1-year.

Results

A total of 43 patients participated (60.73 ± 11.73 years; 30.43% females). The intervention was safe. Creatinine increased and glomerular filtration rate declined at 3 months but normalized after discontinuing CM. We observed a statistically significant increase in the 6-minute walk test (48.69 ± 32.76; P = .005), a reduction in Borg scale exertion (−1.57 ± −1.73 points; P < .01), and decreased heart rate increment during exercise (−2.43 ± −8.66 bpm; P = .04). HRQoL improved significantly (4.08 ± 12.29 points; P = .03). No changes were found in echocardiographic parameters, HF decompensations, or mortality.

Conclusions

CM supplementation in patients with HF and reduced ejection fraction is safe and could improve functional capacity and HRQoL. Further research is warranted to confirm our results.

前言和目的心力衰竭（HF）是一个重大的全球健康负担。心衰患者的运动耐受性降低，极大地影响了他们的生活质量。虽然一水肌酸（CM）可以改善健康人的功能，但其在心衰患者中的作用仍未得到研究。方法我们进行了一项探索性、前瞻性、单中心、开放标签的研究，评估了5 g/d CM在3个月期间对心力衰竭和射血分数降低患者的有效性和安全性。结果包括3个月时的功能能力、健康相关生活质量（HRQoL）、超声心动图和实验室参数以及1年时的HF失代偿和死亡率。结果共43例患者参与(60.73±11.73年；30.43%的女性)。干预是安全的。肌酐升高，肾小球滤过率在3个月时下降，但停药后恢复正常。我们观察到6分钟步行测试(48.69±32.76；P = 0.005)， Borg量表用力减少(- 1.57±- 1.73分；P & lt;.01)，运动时心率增加降低(- 2.43±- 8.66 bpm；p = .04)。HRQoL显著改善（4.08±12.29分）；p = .03)。超声心动图参数、心衰失代偿或死亡率均未见变化。结论在心力衰竭伴射血分数降低的患者中补充scm是安全的，并能改善功能能力和HRQoL。需要进一步的研究来证实我们的结果。

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引用次数: 0

Comité Organizador y Comité Científico 组织委员会和科学委员会

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REC: CardioClinics

Pub Date : 2025-04-01 DOI: 10.1016/S2605-1532(25)00077-9

引用次数: 0

Comunicaciones 通信

Q4 Medicine

REC: CardioClinics

Pub Date : 2025-04-01 DOI: 10.1016/S2605-1532(25)00078-0

引用次数: 0

Factibilidad y precisión de la impresión 3D a través de ecocardiografía transtorácica 3D en pacientes pediátricos 通过3D胸腔超声心动图对儿科患者进行3D打印的可行性和准确性

Q4 Medicine

REC: CardioClinics

Pub Date : 2025-04-01 DOI: 10.1016/j.rccl.2024.12.002

Luis Antonio Jiménez Salinas , Clara A. Vázquez Antona , Tomás Efraín Sánchez Pérez , Juan Carlos Barrera de la Torre , Ana Laura Trujeque Ruiz

Introduction and objectives

Three-dimensional (3D) printing applied to cardiology has demonstrated its usefulness, supporting the planning of surgical and interventional procedures, especially for congenital heart disease. Although printed models have been documented using transesophageal echocardiography images, this technique has limitations in small pediatric patients. The objective was to determine the feasibility and accuracy of digital and printed 3D models obtained from the acquisition of transthoracic images in pediatric patients with ventricular septal defect.

Methods

Five pediatric patients with different locations of the defect were studied. Echocardiographic data were extracted, images processed, segmentation conducted, designs optimized, and models printed; the morphology, diameters of the defect, and their spatial relationships were analyzed.

Results

The correlation between the measurements obtained from 3D echocardiography and the digital 3D models and printed models was high (correlation coefficients of 0.953 and 0.952, respectively). The mean absolute difference between the values obtained by 3D echocardiography and the digital 3D models was 0.064 mm, while the mean absolute difference between the values obtained by 3D echocardiography and the printed models was 0.644 mm. There were no statistically significant differences between echocardiography and the models.

Conclusions

3D digital and printed models obtained from transthoracic echocardiographic data in pediatric patients are technically feasible and accurately reflect the morphology, spatial relationships, and dimensions of the different types of ventricular septal defect. However, the visualization of the models may vary according to the location of the defect, with muscle defects being easier to represent compared to perimembranous defects.

介绍和目的三维（3D）打印在心脏病学中的应用已经证明了它的实用性，它支持外科和介入手术的规划，特别是对于先天性心脏病。虽然经食管超声心动图图像已证实打印模型，但该技术在小儿科患者中有局限性。目的是确定数字和打印3D模型的可行性和准确性，这些模型是通过获取小儿室间隔缺损患者的经胸图像获得的。方法对5例小儿不同部位的先天性缺陷进行分析。超声心动图数据提取、图像处理、分割、设计优化、模型打印；分析了缺陷的形貌、直径及其空间关系。结果三维超声心动图测量值与数字三维模型和打印模型的相关性较高，相关系数分别为0.953和0.952。三维超声心动图与数字三维模型的平均绝对差为0.064 mm， 3D超声心动图与打印模型的平均绝对差为0.644 mm。超声心动图与模型比较无统计学差异。结论利用小儿经胸超声心动图数据建立三维数字和打印模型在技术上是可行的，能准确反映不同类型室间隔缺损的形态、空间关系和尺寸。然而，模型的可视化可能因缺陷的位置而异，与膜周缺陷相比，肌肉缺陷更容易表示。

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引用次数: 0

Desplazamiento de Holter subcutáneo a la cavidad pleural 皮下Holter移位至胸腔

Q4 Medicine

REC: CardioClinics

Pub Date : 2025-04-01 DOI: 10.1016/j.rccl.2024.10.004

Miguel Cayetano Amores Luque , Cristina Cavestany García-Matres , José Luis Zamorano Gómez , Javier Moreno

引用次数: 0

Recomendaciones para la optimización de la atención a los pacientes tras infarto agudo de miocardio. Proyecto MIMIC 优化急性心肌梗死患者护理的建议。MIMIC项目

Q4 Medicine

REC: CardioClinics

Pub Date : 2025-04-01 DOI: 10.1016/j.rccl.2024.11.003

José M. de la Torre-Hernández , Guillermo Aldama-López , Rut Andrea , Miguel Corbí-Pascual , Alberto Cordero , María Rosa Fernández Olmo , Xavier García-Moll , Antonio García Quintana , Arantxa Matalí , Miriam Sandín Rollán , Xoana Taboada , Ana Viana Tejedor , Sergio Raposeiras-Roubín

In recent years, efforts in the care of acute myocardial infarction (AMI) have focused on ensuring a rapid response during the acute phase. However, follow-up after hospitalization is essential for adequate recovery and the prevention of future complications. Heart failure following an infarction is a common complication that implies a worse prognosis and a high rate of readmission, increasing the risk of death both in its early phase and in the long term. The Myocardial infarction and heart failure model (MIMIC) project analyzed patient care after an AMI in different healthcare models, with the aim of identifying recommendations for improvement and best practices that contribute to generalizing optimal care models after an AMI, to achieve a better prognosis, a higher quality of life, and a reduction in healthcare costs.

近年来，在急性心肌梗死（AMI）的护理努力集中在确保在急性期的快速反应。然而，住院后的随访对于充分恢复和预防未来并发症至关重要。梗死后心力衰竭是一种常见的并发症，意味着预后较差和再入院率高，增加了早期和长期死亡的风险。心肌梗死和心力衰竭模型（MIMIC）项目分析了AMI后不同医疗模式下的患者护理，目的是确定改进建议和最佳实践，有助于推广AMI后最佳护理模式，以实现更好的预后、更高的生活质量和降低医疗成本。

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引用次数: 0

Índice de autores 作者索引

Q4 Medicine

REC: CardioClinics

Pub Date : 2025-04-01 DOI: 10.1016/S2605-1532(25)00079-2

引用次数: 0

Actualización del posicionamiento sobre obesidad y enfermedad cardiovascular y renal de las Asociaciones de Cardiología Preventiva, Cardiología Clínica e Insuficiencia Cardiaca de la SEC 更新美国证券交易委员会预防心脏病学、临床心脏病学和心力衰竭协会关于肥胖、心血管和肾脏疾病的立场

Q4 Medicine

REC: CardioClinics

Pub Date : 2025-04-01 DOI: 10.1016/j.rccl.2024.11.004

Almudena Castro Conde , Juan José Gorgojo Martínez , Nicolás Manito Lorite

引用次数: 0

CARABELA-HF: new frontiers in the optimization of heart failure clinical management in Spain CARABELA-HF：西班牙心力衰竭临床管理优化的新领域

Q4 Medicine

REC: CardioClinics

Pub Date : 2025-04-01 DOI: 10.1016/j.rccl.2024.09.001

Álvaro González Franco , José Francisco Soto , Inmaculada Mediavilla , Manuel Leal , Manuel Anguita , on behalf of the CARABELA-HF Scientific Committee

引用次数: 0

Influence of COVID-19 on the prevalence of diabetes mellitus and use of health care services in Gran Canaria COVID-19对大加那利岛糖尿病患病率和卫生保健服务使用的影响

Q4 Medicine

REC: CardioClinics

Pub Date : 2025-04-01 DOI: 10.1016/j.rccl.2025.01.008

Roberto Sánchez Medina , Alejandro de Arriba Fernández , Ángela Gutiérrez Pérez , José Luis Alonso Bilbao

Introduction and objectives

The prevalence of diabetes mellitus (DM) has increased faster in low- and middle-income countries. We determined how the COVID-19 pandemic may have affected the relationship between income level and prevalence of DM, disease management, and the use of primary care services.

Methods

Descriptive cross-sectional study. It included diabetic patients over 14 years of age residing in Las Palmas de Gran Canaria as of 31 December 2022. The results were compared with those of a pre-pandemic study in 2019.

Results

The prevalence of DM in 2022 in Las Palmas de Gran Canaria was almost identical to that of 2019, with a slight decrease in the low- and high-income groups, and an increase in the middle-income group. The average age of the population with DM increased. The average number of visits to the doctor increased, while visits to the nursing home decreased. A worsening of glycosylated hemoglobin and low-density lipoproteins was found in high and middle incomes. The trend was the opposite for body weight, with a 1.2% increase in the prevalence of overweight/obesity in low incomes.

Conclusions

Lower incomes were associated with worse outcomes in terms of overweight and obesity. The situation of people with DM with overweight or obesity worsened compared to 2019 for the lower-income population.

前言和目标糖尿病（DM）的患病率在低收入和中等收入国家增长较快。我们确定了COVID-19大流行如何影响收入水平与糖尿病患病率、疾病管理和初级保健服务使用之间的关系。方法描述性横断面研究。它包括截至2022年12月31日居住在大加那利岛拉斯帕尔马斯的14岁以上的糖尿病患者。研究结果与2019年大流行前的一项研究结果进行了比较。结果2022年拉斯帕尔马斯岛的糖尿病患病率与2019年基本相同，低收入和高收入人群略有下降，中等收入人群略有上升。糖尿病患者的平均年龄增加。看医生的平均次数增加了，而去养老院的次数减少了。糖化血红蛋白和低密度脂蛋白在中高收入人群中呈恶化趋势。体重的趋势正好相反，低收入人群超重/肥胖的患病率增加了1.2%。结论在超重和肥胖方面，较低的收入与较差的结果相关。与2019年相比，低收入人群中伴有超重或肥胖的糖尿病患者的情况有所恶化。

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