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SPINAL TUMORS: A CONCEPT OF INTEGRATED ASSESSMENT IN RELATION TO EMERGENCY CONDITIONS 脊柱肿瘤:与紧急情况有关的综合评估概念
Q3 Medicine Pub Date : 2018-09-19 DOI: 10.14531/SS2018.3.92-99
M. A. Mushkin, A. K. Dulaev, A. Mushkin, М. А. Мушкин, Александр Кайсинович Дулаев, А. Ю. Мушкин
A modern concept of assessing tumor lesions of the spine, NOMS, adapted to the conditions of emergency care is presented as a part of a systematic review of the literature. Principles of neurological, oncological, mechanical and system analysis of spine lesions in primary and metastatic spinal tumors, which are the basis for step-by-step tactical decisions, as well as methods for analyzing each component are described.
评估脊柱肿瘤病变的现代概念,NOMS,适应紧急护理的条件,提出了作为文献系统综述的一部分。在原发性和转移性脊柱肿瘤中脊柱病变的神经学、肿瘤学、力学和系统分析原理,这是一步一步战术决策的基础,以及分析每个组成部分的方法。
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引用次数: 0
SURGICAL CORRECTION OF ADULT IDIOPATHIC SCOLIOSIS IN PATIENTS OF YOUNG AND MIDDLE AGE 中青年成人特发性脊柱侧凸的手术矫正
Q3 Medicine Pub Date : 2018-09-19 DOI: 10.14531/ss2018.3.52-60
M. Mikhaylovskiy, A. Vasyura, V. Novikov, V. Sarnadsky, E. V. Gubina, M. A. Chernyadjeva
Objective.To evaluate the results of surgical correction of idiopathic scoliosis in patients aged 18-50 years, in terms of different age groups.Material and Methods.A total of 393 patients (348 women, 45 men) with idiopathic scoliosis were operated on during 1996-2015. In all cases, posterior correction of the deformity was performed using segmental third-generation instrumentation. The primary curve and structural countercurve were included in the fusion area. Hook fixation was performed in 298 cases, and hybrid (hooks and pedicle screws) in 95. The period of postoperative follow-up was 4.4 years on average. Analysis of immediate and long-term results was performed using X-ray and computer optical topography in three age groups (age at the time of surgery): 18 to 24 years (274 patients), 25 to 34 years (95 patients), 35 years and older (24 patients).Results.No statistically significant differences between age groups were revealed, both in initial parameters (magnitude of the primary curve, countercurve, and the apical vertebra rotation) and in surgical results (magnitude of correction, loss of correction and mobility). When interviewing patients with the SRS-24 questionnaire, the best results were obtained in the group of age 18-24, worse in the group of age 25-34, and even worse in the group of age over 35. Computer topography also revealed the absence of statistically significant difference between age groups.Conclusion.Surgical treatment of adult idiopathic scoliosis provides quite satisfactory results, especially in terms of improving the quality of life, that do not have significant differences when comparing three age groups within the age range exceeding 30 years. 
目标。目的:评价18-50岁特发性脊柱侧凸不同年龄组的手术矫正效果。材料和方法。1996-2015年间,共有393例特发性脊柱侧凸患者(女性348例,男性45例)接受手术治疗。所有病例均采用第三代节段性内固定进行后路畸形矫正。融合区包括主曲线和结构反曲线。钩固定298例,混合(钩和椎弓根螺钉)95例。术后随访时间平均4.4年。采用x线和计算机光学地形图对3个年龄组(手术时年龄)的近期和远期结果进行分析:18 ~ 24岁(274例),25 ~ 34岁(95例),35岁及以上(24例)。在初始参数(主曲线、反曲线和根尖椎体旋转的大小)和手术结果(矫正的大小、矫正的损失和活动能力)方面,年龄组之间没有统计学上的显著差异。使用SRS-24问卷对患者进行访谈时,18-24岁组效果最好,25-34岁组效果较差,35岁以上组效果更差。结论:成人特发性脊柱侧凸的手术治疗效果相当满意,特别是在改善生活质量方面,在30岁以上的年龄范围内,三个年龄组比较无显著差异。
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引用次数: 1
ANALYSIS OF C1, C2 SCREW FIXATION FOR ATLANTOAXIAL INSTABILITY IN PATIENTS OF DIFFERENT AGE GROUPS c1、c2螺钉固定治疗不同年龄组寰枢椎不稳的分析
Q3 Medicine Pub Date : 2018-09-19 DOI: 10.14531/ss2018.3.6-12
A. Gubin, A. Burtsev, S. Ryabykh, V. Klimov, A. Evsyukov, D. Ivliev
Objective. To analyze feasibility and safety of C1, C2 fixation for craniocervical stabilization in patients of different age groups.Material and Methods. Study design is a retrospective multicenter cohort analysis. Level of evidence – II. The study was based on the diagnosis and treatment data of 43 patients aged 5–74 years who underwent C1, C2 screw fixation.Results. In most cases, atlantoaxial instability was due to traumatic injuries. Screws were implanted in C1 in 81 cases, and in C2 in 80. Postoperative MSCT data were evaluated in 41 patients. The position of the screws in C1 was defined as ideal in 63,0 % of cases, in the remaining cases there were malpositions, with 6 screws having double malpositions. Out of 80 screws inserted in C2, 64 were implanted transpedicularly. In 59.5 % of cases, a good position was revealed; in other cases different malpositions were noted. In none of the cases neurovascular damage or clinical manifestation occurred.Conclusion. Analysis of screw fixation of C1, C2 showed that this technique is feasible in patients of different age groups. Duration of surgery and blood loss did not go beyond the conventional values. Postoperative malpositions are not accompanied by neurological disorders, which allows to consider this fixation quite safe.
目标。分析C1、C2固定用于不同年龄组患者颅颈稳定的可行性及安全性。材料和方法。研究设计为回顾性多中心队列分析。证据水平- 2。本研究基于43例5-74岁接受C1, C2螺钉固定的患者的诊断和治疗资料。在大多数病例中,寰枢椎不稳定是由于外伤性损伤。螺钉植入C1 81例,C2 80例。对41例患者的术后MSCT数据进行了评估。63,0 %的病例认为C1螺钉位置理想,其余病例出现错位,其中6例出现双错位。在80枚C2螺钉中,64枚经椎弓根植入。在59.5%的病例中,良好的位置显露;在其他情况下,注意到不同的错位。所有病例均未出现神经血管损伤或临床表现。对C1、C2螺钉固定的分析表明,该技术适用于不同年龄组的患者。手术时间和出血量没有超出常规值。术后错位不伴有神经系统疾病,因此可以认为这种固定是相当安全的。
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引用次数: 0
PREDICTION OF SURGICAL SITE INFECTION IN SPINE SURGERY 脊柱外科手术部位感染的预测
Q3 Medicine Pub Date : 2018-06-09 DOI: 10.14531/SS2018.2.84-90
V. M. Haydarov, A. N. Tkachenko, I. A. Kirilova, D. Mansurov
Objective. To analyze prognostic factors for the development of surgical site infection following spine surgery and evaluate rating values for each of them. Material and Methods . The data on 325 patients who underwent spinal surgery were analyzed. Data on 177 patients of the retrospective group who underwent spinal surgery without infectious complications were compared with the data of patients who had local complications of infectious genesis within one year after the operation (36 observations). Results. The study resulted in creation of a learning matrix which became the basis for mathematical prediction and algorithm for the prevention of local infectious complications in patients who underwent spinal surgery. Seventeen criteria for predicting the development of surgical site infection were identified. Conclusion. Approbation of the program in a prospective study (112 cases) with a follow-up period of 12 months after surgery demonstrated significant decrease in the incidence of surgical site infection  as compared with that in the retrospective study group (from 16.9 to 9.8 %).
客观的分析脊柱手术后发生手术部位感染的预后因素,并评估每种因素的评分值。材料和方法。对325例接受脊柱手术的患者的数据进行了分析。将177名接受脊柱手术但无感染性并发症的回顾性组患者的数据与术后一年内有感染性并发症局部患者的数据进行比较(36项观察)。后果这项研究创建了一个学习矩阵,该矩阵成为预防脊柱手术患者局部感染并发症的数学预测和算法的基础。确定了17个预测手术部位感染发展的标准。结论在一项前瞻性研究(112例)中,术后随访12个月,与回顾性研究组相比,手术部位感染的发生率显著降低(从16.9%降至9.8%)。
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引用次数: 3
COMPARATIVE ANALYSIS OF METHODS TO PREVENT CICATRICIAL ADHESIVE EPIDURITIS AFTER MICRODISCECTOMY IN THE LUMBOSACRAL SPINE 腰骶椎显微椎间盘切除术后瘢痕粘连性皮炎预防方法的比较分析
Q3 Medicine Pub Date : 2018-06-09 DOI: 10.14531/ss2018.2.56-65
D. M. Zavyalov, V. Orlov, M. N. Kravtsov, K. Babichev
Objective. To analyze the effectiveness of methods for the prevention of cicatricial adhesive epiduritis (CAE) after lumbar microdiscectomy. Material and Methods. The results of treatment of 108 patients with herniated intervertebral discs at the lumbosacral level were analyzed. Cicatricial adhesive epiduritis was prevented using 4 % sodium carboxymethylcellulose gel in Group I (n = 36), by placing autograft from the internal leaf of the lumbar fascia into the space between the vertebral arches in Group II (n = 32), and prevention of CAE was not carried out in Group III (n = 40). Results. Complete examination of patients after microsurgical removal of the herniated lumbar intervertebral disc revealed cicatricial adhesive changes in the epidural space in all studied groups, though the degree of their expression was different: in Groups I and II, cicatricial adhesive epiduritis was insignificant without clinical manifestations, in Group III, clinical manifestations were observed. Conclusion. The proposed methods for prevention of cicatricial adhesive epiduritis after microsurgical treatment of herniated lumbar intervertebral disc protect the epidural space and perform a barrier function.
客观的分析腰椎微椎间盘切除术后瘢痕粘连性脱皮炎(CAE)预防方法的有效性。材料和方法。对108例腰骶部椎间盘突出症患者的治疗结果进行分析。在第I组(n=36)中,使用4%羧甲基纤维素钠凝胶,通过将自体移植物从腰筋膜内叶放置到第II组(n=32)中的脊椎弓之间的空隙中,预防了瘢痕粘连性皮炎,而在第III组(n=40)中,未进行CAE的预防。后果对所有研究组的患者在显微手术切除突出的腰椎间盘后进行的全面检查显示,硬膜外间隙发生了瘢痕性粘连变化,尽管其表达程度不同:在I组和II组中,瘢痕性粘连性肠胃炎不明显,没有临床表现,在III组中,观察到临床表现。结论所提出的预防腰椎间盘突出症显微外科治疗后瘢痕性粘连性肠胃炎的方法保护硬膜外间隙并发挥屏障功能。
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引用次数: 0
INTRAOPERATIVE DIAGNOSIS OF NEUROLOGICAL COMPLICATIONS IN SURGERY OF SEVERE SCOLIOSIS: REPORT OF CLINICAL CASES 重度脊柱侧凸手术中神经系统并发症的术中诊断:临床病例报告
Q3 Medicine Pub Date : 2018-06-09 DOI: 10.14531/SS2018.2.7-11
A. Vasyura, M. Mikhaylovskiy, V. Novikov, E. V. Chesheva
Clinical observations of 13- and 15-year-old patients with severe (118° and 133°) idiopathic scoliosis, subjected to operative correction with the use of segmental instrumentation are presented. Intraoperative monitoring of the spinal cord function was performed by recording motor potentials of the brain and skin thermometry from the lower limbs (authors’ technique). During the operation, there was a gradual decrease in potentials in one case and sharp in another, with no changes in cutaneous temperature. Based on the data of skin thermometry, surgeons decided not to remove the implant and to bring the operation to completion in both cases. In the postoperative period, neurological complications were not revealed. The conclusion is made about the advisability of including the skin thermometry in a complex of intraoperative monitoring of spinal cord function in patients with spine deformities.
本文介绍了13岁和15岁的严重(118°和133°)特发性脊柱侧凸患者的临床观察,这些患者采用节段性内固定进行手术矫正。术中通过记录脑运动电位和下肢皮肤温度来监测脊髓功能(作者的技术)。术中,1例电位逐渐下降,1例电位急剧下降,皮肤温度无变化。根据皮肤测温数据,外科医生决定不移除植入物,并完成这两例手术。术后未发现神经系统并发症。结论:在脊柱畸形患者术中对脊髓功能进行综合监测时,皮肤测温是可取的。
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引用次数: 1
ADVERSE DRUG REACTIONS TO LOCAL INTRAWOUND VANCOMYCIN APPLICATION AFTER POSTERIOR LUMBOSACRAL FUSION 腰骶后路融合术后局部创面内应用万古霉素的不良反应
Q3 Medicine Pub Date : 2018-06-09 DOI: 10.14531/SS2018.2.76-83
V. Byvaltsev, I. Stepanov, V. Borisov
Objective. To analyze the types and frequency of adverse drug reactions to local intrawound application of vancomycin powder in patients after posterior decompression and stabilization in the lumbosacral spine. Material and Methods . Clinical series published in 2011–2017 were analyzed. At the first stage, Medline and PubMed databases were searched for English-language literature sources using the keywords «intrawound vancomycin», «surgical site infection», and «posterior lumbar fusion», and e-Library for Russian-language sources using «local application of vancomycin powder», «infection in the surgical site», and «posterior decompression and stabilization». At the second stage, abstracts of articles were examined, and publications that did not meet the research criteria were excluded. At the third stage, the full texts of the selected articles were reviewed for compliance with inclusion criteria, as well as references for relevant studies. Results. Nineteen clinical studies (16 retrospective and 3 prospective) with a total of 13,077 patients were selected for a systematic review. In 55.3 % (7,236) of posterior lumbosacral surgery cases, vancomycin powder was applied locally to prevent surgical site infection. Among the entire cohort of patients, unwanted drug reactions were detected in 2.19 % of patients. Conclusions. Local application of vancomycin powder is associated with a low incidence of unwanted drug reactions.
目标。目的分析腰骶椎后路减压稳定术后局部伤口内应用万古霉素粉的不良反应类型及发生频率。材料和方法。分析2011-2017年发表的临床丛书。在第一阶段,使用关键词“伤口万古霉素”、“手术部位感染”和“腰椎后路融合”搜索Medline和PubMed数据库的英文文献来源,并使用“万古霉素粉的局部应用”、“手术部位感染”和“后路减压和稳定”搜索俄语文献来源的电子图书馆。在第二阶段,对文章的摘要进行审查,不符合研究标准的出版物被排除在外。在第三阶段,审查选定文章的全文是否符合纳入标准,以及相关研究的参考文献。结果。19项临床研究(16项回顾性研究,3项前瞻性研究)共13077例患者入选系统评价。在55.3%(7236例)的腰骶后路手术病例中,局部应用万古霉素粉剂预防手术部位感染。在整个队列患者中,2.19%的患者检测到不良药物反应。结论。局部应用万古霉素粉剂与不良药物反应发生率低有关。
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引用次数: 3
SURGICAL CORRECTION OF SUBAXIAL KYPHOSIS IN A CHILD WITH TYPE I NEUROFIBROMATOSIS: RARE CLINICAL CASE AND LITERATURE REVIEW 1例I型神经纤维瘤病儿童轴下型后凸的手术矫正:罕见临床病例及文献复习
Q3 Medicine Pub Date : 2018-06-09 DOI: 10.14531/ss2018.2.12-17
D. Malamashin, M. M. Schelkunov, M. A. Krasnikov, A. Mushkin
The paper presents a case of rapidly developing severe cervical kyphosis in a 5-year-old child which was the first clinical manifestation of type I neurofibromatosis (NF1). Surgical correction was carried out in two stages with preliminary hardware halo-traction and subsequent reconstruction of the spine using titanium mesh cage with bone autograft and posterior instrumentation. The deformity was corrected from the magnitude of 79° to the restoration of physiological lordosis. Long-term results were followed-up for 2.5 years with full maintenance of the achieved deformity correction. A 15-year literature review on the cervical spine lesions in NF1 is presented.
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引用次数: 1
NEW PLASTIC MATERIAL FOR THE TREATMENT OF VERTEBRAL PATHOLOGY AND NOT ONLY... 新型塑料材料治疗椎体病理,不仅…
Q3 Medicine Pub Date : 2018-06-09 DOI: 10.14531/SS2018.2.91-97
A. Zaidman
The paper presents results of the author’s multi-year research in the field of cellular technologies. The differentiation stages of the chondro-osseous graft are described based on the findings of morphological, ultrastructural, and molecular genetic studies. The stages of cell transformation, dynamics of synthetic processes and matrix formation are identified. Hypotheses of the histogenesis of initial stages of different types of bone tissue, and the formation of microcirculatory and vascular beds in the process of osteogenesis are suggested. Experimental testing of regenerative potentialities of the bone graft in animals has shown that it is a primitive bone tissue with a high potency to proliferation, formation and differentiation into definitive bone tissue within a transplant zone.
本文介绍了作者多年来在蜂窝技术领域的研究成果。根据形态学、超微结构和分子遗传学的研究结果,描述了软骨骨移植物的分化阶段。确定了细胞转化的阶段、合成过程的动力学和基质的形成。对不同类型骨组织初始阶段的组织发生、成骨过程中微循环和血管床的形成提出了假设。动物骨移植再生潜力的实验测试表明,它是一种原始的骨组织,在移植区域内具有很高的增殖、形成和分化成最终骨组织的能力。
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引用次数: 2
ON THE EXTENT OF PREOPERATIVE RADIOLOGICAL AND CT EXAMINATION OF PATIENTS WITH DEGENERATIVE DISEASES OF THE LUMBAR SPINE 腰椎退行性疾病患者术前放射学和ct检查的范围
Q3 Medicine Pub Date : 2018-06-09 DOI: 10.14531/ss2018.2.66-75
A. Krutko, A. Sanginov
Objective. To specify the extent of preoperative examination of patients with lumbar degenerative diseases and to study the effect of examination results on the tactics of surgical treatment. Material and Methods. The study included retrospective analysis of 1340 patients with lumbar degenerative diseases treated in the Neurosurgical Department No. 2 of Novosibirsk RITO n.a. Ya.L. Tsivyan during 2017. Results. The average height of the intervertebral disc as evaluated with MRI was 7.4 ± 1.8 mm, and that evaluated with MSCT – 4.9 ± 1.5 mm, with a statistically significant difference between them (p < 0.05). Immediate preoperative examination of patients with lumbar disc herniation showed reduction or lysis of the hernia fragment in some of them. Reduction of the leg pain and hernia size (by more than 50 %) and lysis of the herniated disc fragment evidenced by MRI were observed in 21 (3.2 %) patients. Comparison of the preplanned and actually performed extent of decompression and stabilization interventions showed that tactics and/ or extent of surgical treatment changed in 37.6 % of cases. Conclusion. The complex of instrumental radiological and neuroimaging studies, as well as methods of provocative procedure in the lumbar spine performed immediately before the planned surgical treatment allow choosing the proper treatment tactics, specifying or correcting the volume of surgical treatment, and to prognosing its outcome in lumbar degenerative diseases.
客观的明确腰椎退行性疾病患者术前检查的范围,并研究检查结果对手术治疗策略的影响。材料和方法。该研究包括对2017年在新西伯利亚RITO n.a.Ya.L Tsivyan第二神经外科接受治疗的1340名腰椎退行性疾病患者的回顾性分析。后果MRI评估的椎间盘平均高度为7.4±1.8 mm,MSCT评估的椎间盘中平均高度为4.9±1.5 mm,两者之间存在统计学显著差异(p<0.05)。腰椎间盘突出症患者术前立即检查显示,其中一些患者的疝片减少或溶解。在21名(3.2%)患者中观察到腿部疼痛和疝气大小减轻(超过50%)以及椎间盘突出碎片溶解。对预先计划和实际实施的减压和稳定干预程度的比较表明,37.6%的病例的手术治疗策略和/或程度发生了变化。结论仪器放射学和神经影像学研究的复杂性,以及在计划的手术治疗前立即对腰椎进行挑衅性手术的方法,使我们能够选择正确的治疗策略,指定或纠正手术治疗的量,并预测其在腰椎退行性疾病中的结果。
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引用次数: 1
期刊
Hirurgia Pozvonochnika
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