Pub Date : 2023-06-01DOI: 10.33192/smj.v75i6.261124
Nicholas Carriker, Sirichai Hongsanguansri, Chosita Pavasuthipaisit, Komsan Kiatrungrit
Objective: This study aimed to find the association among body image focused social media usage (BSMU), resilience, attachment, and eating-related problems among Thai adolescents. Materials and Methods: Cross-sectional descriptive research was conducted with a sample of 495 high school students from three schools in Bangkok. The participants answered an online questionnaire comprised of age, sex, height/weight, BSMU, Body-esteem Scale for Adolescents and Adults, Eating Attitudes Test, Inventory of Parent and Peer Attachment for Children, and the Thai Resilience Quotient. Descriptive statistics were used to analyze demographic information, body satisfaction, resilience, attachment, and eating-related problems. T-tests, chi-square, and multivariate logistic regression analysis were performed to explore the associations between these variables. Results: Mean (SD) age was 17.06 (0.805), with 307 female participants (62%). Time spent on social media was found to be associated with increased risk of binging (AOR (CI) = 1.71 (1.14-2.56)). BSMU was associated with increased risk of inappropriate eating attitudes, binging, purging and using laxative (AOR (CI) = 1.14 (1.03-1.27), 1.14 (1.06-1.22), 1.20 (1.04-1.40), and 1.21 (1.09-1.34) respectively). Higher resilience was found to associated with lower risk in binging (AOR (CI) = 0.45 (0.21-0.97)). However, attachment is not associated with any of eating-related problems. Conclusion: BSMU usage was associated with inappropriate eating attitudes and behavior. Findings also suggest that higher resilience and stronger attachment were associated with lower risk of eating-related problems. The effectiveness of resilience and attachment improvement programs should be explored to help protect against eating problems.
{"title":"Association between Body Image Focused Social Media Usage (BSMU), Resilience, Attachment and Eating-related Problems among High School Students in Bangkok","authors":"Nicholas Carriker, Sirichai Hongsanguansri, Chosita Pavasuthipaisit, Komsan Kiatrungrit","doi":"10.33192/smj.v75i6.261124","DOIUrl":"https://doi.org/10.33192/smj.v75i6.261124","url":null,"abstract":"Objective: This study aimed to find the association among body image focused social media usage (BSMU), resilience, attachment, and eating-related problems among Thai adolescents.\u0000Materials and Methods: Cross-sectional descriptive research was conducted with a sample of 495 high school students from three schools in Bangkok. The participants answered an online questionnaire comprised of age, sex, height/weight, BSMU, Body-esteem Scale for Adolescents and Adults, Eating Attitudes Test, Inventory of Parent and Peer Attachment for Children, and the Thai Resilience Quotient. Descriptive statistics were used to analyze demographic information, body satisfaction, resilience, attachment, and eating-related problems. T-tests, chi-square, and multivariate logistic regression analysis were performed to explore the associations between these variables.\u0000Results: Mean (SD) age was 17.06 (0.805), with 307 female participants (62%). Time spent on social media was found to be associated with increased risk of binging (AOR (CI) = 1.71 (1.14-2.56)). BSMU was associated with increased risk of inappropriate eating attitudes, binging, purging and using laxative (AOR (CI) = 1.14 (1.03-1.27), 1.14 (1.06-1.22), 1.20 (1.04-1.40), and 1.21 (1.09-1.34) respectively). Higher resilience was found to associated with lower risk in binging (AOR (CI) = 0.45 (0.21-0.97)). However, attachment is not associated with any of eating-related problems.\u0000Conclusion: BSMU usage was associated with inappropriate eating attitudes and behavior. Findings also suggest that higher resilience and stronger attachment were associated with lower risk of eating-related problems. The effectiveness of resilience and attachment improvement programs should be explored to help protect against eating problems.","PeriodicalId":37270,"journal":{"name":"Siriraj Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48555937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-01DOI: 10.33192/smj.v75i6.261096
Juthamas Hannarong, Teerapong Tocharoenchok
Objective: Our aim was to report on the long-term outcomes of patients who underwent RV-PA conduit placement at our institute. Materials and Methods: We retrospectively reviewed 407 RV-PA conduit placements from January 1997 to December 2018. The primary outcomes were freedom from and risk factor(s) for conduit re-operation. The secondary outcomes were survival, freedom from conduit dysfunction and conduit-related catheter intervention. Results: Of all the included patients, 209 were male (51.4%) and the median age at the operation was nine years (IQR 6, 18 years). The most commonly used conduit types were bovine jugular vein conduit (125, 30.7%), pulmonary homograft (122, 30.0%), and aortic homograft (76, 18.7%). The median follow-up time was 5.1 years (IQR 0.9, 9.2 years). The overall survival was 92.2% at 5 years. Freedom from re-operation was 95.4% and 84.2%, at 5 and 10 years. Factors related to conduit reoperation were age at operation less than 1 year, diagnosis rather than pulmonary atresia or stenosis, conduit size less than 18 mm, and conduit z-score greater than 3 (all p<0.01). In multivariate analysis, a significant contributing factor for re-operation was small conduit size (13 mm or smaller; HR 6.87 (95%CI 2.36, 20.01); p<0.001, 14–17 mm; HR 3.20 (95%CI 1.28, 8.00); p=0.013). Freedom from conduit dysfunction was 84.4% and 61.6% at 5 and 10 years. Freedom from conduit intervention was 94.4% and 89.3% at 5 and 10 years. Conclusion: Our study showed that patients had excellent survival with acceptable freedom from re-operation despite deteriorated conduit function. Small conduit size is associated with re-operation.
{"title":"Long-Term Outcomes After Right Ventricular Outflow Tract Conduit Placement","authors":"Juthamas Hannarong, Teerapong Tocharoenchok","doi":"10.33192/smj.v75i6.261096","DOIUrl":"https://doi.org/10.33192/smj.v75i6.261096","url":null,"abstract":"Objective: Our aim was to report on the long-term outcomes of patients who underwent RV-PA conduit placement at our institute.\u0000Materials and Methods: We retrospectively reviewed 407 RV-PA conduit placements from January 1997 to December 2018. The primary outcomes were freedom from and risk factor(s) for conduit re-operation. The secondary outcomes were survival, freedom from conduit dysfunction and conduit-related catheter intervention.\u0000Results: Of all the included patients, 209 were male (51.4%) and the median age at the operation was nine years (IQR 6, 18 years). The most commonly used conduit types were bovine jugular vein conduit (125, 30.7%), pulmonary homograft (122, 30.0%), and aortic homograft (76, 18.7%). The median follow-up time was 5.1 years (IQR 0.9, 9.2 years). The overall survival was 92.2% at 5 years. Freedom from re-operation was 95.4% and 84.2%, at 5 and 10 years. Factors related to conduit reoperation were age at operation less than 1 year, diagnosis rather than pulmonary atresia or stenosis, conduit size less than 18 mm, and conduit z-score greater than 3 (all p<0.01). In multivariate analysis, a significant contributing factor for re-operation was small conduit size (13 mm or smaller; HR 6.87 (95%CI 2.36, 20.01); p<0.001, 14–17 mm; HR 3.20 (95%CI 1.28, 8.00); p=0.013). Freedom from conduit dysfunction was 84.4% and 61.6% at 5 and 10 years. Freedom from conduit intervention was 94.4% and 89.3% at 5 and 10 years.\u0000Conclusion: Our study showed that patients had excellent survival with acceptable freedom from re-operation despite deteriorated conduit function. Small conduit size is associated with re-operation.","PeriodicalId":37270,"journal":{"name":"Siriraj Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46558176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-01DOI: 10.33192/smj.v75i6.261881
Chavalit Chotruangnapa, Piyawan Thongdang
Objective: To compare blood pressure (BP) and heart rate measured by attended and unattended automated office blood pressure measurement (AOBPM) versus home blood pressure measurement (HBPM) and the effect of unattended AOBPM on the classification of BP phenotypes. Materials and Methods: The cross-sectional study was conducted at the outpatient department in Siriraj Hospital, Thailand. All participants measured their office BP using attended and unattended techniques in random order and recorded home BP twice a day for consecutive 7 days. The agreement between office BP from both AOBPM methods and that from HBPM was analyzed using the Bland-Altman plot. The change in the proportion of each BP phenotype was also analyzed. Results: We included 114 participants. The mean age was 57.96 + 15.07 years. The average BP from attended AOBPM, unattended AOBPM, and HBPM were 150.52 + 16.12/81.77 + 11.04, 139.68 + 13.80/78.55 + 11.71, and 126.91 + 9.80/76.40 + 8.37 mmHg, respectively. The BP and heart rate measured by these techniques were significantly different (p-value of <0.001). Bland-Altman analysis showed the biases of attended and unattended SBP versus home SBP were 23.61 and 12.77 mmHg, respectively. Unattended AOBPM significantly decreased the numbers of patients classified as white-coat and sustained hypertension regardless of BP thresholds (p-value of <0.001 for both groups). Conclusion: Unattended AOBPM significantly minimizes the white-coat effect in real-life clinical practice and may help physicians avoid overdiagnosis of hypertension. Nevertheless, it does not replace HBPM.
{"title":"The Benefit of Unattended Automated Office Blood Pressure Measurement on the White-coat Effect: A Cross-sectional Study","authors":"Chavalit Chotruangnapa, Piyawan Thongdang","doi":"10.33192/smj.v75i6.261881","DOIUrl":"https://doi.org/10.33192/smj.v75i6.261881","url":null,"abstract":"Objective: To compare blood pressure (BP) and heart rate measured by attended and unattended automated office blood pressure measurement (AOBPM) versus home blood pressure measurement (HBPM) and the effect of unattended AOBPM on the classification of BP phenotypes.\u0000Materials and Methods: The cross-sectional study was conducted at the outpatient department in Siriraj Hospital, Thailand. All participants measured their office BP using attended and unattended techniques in random order and recorded home BP twice a day for consecutive 7 days. The agreement between office BP from both AOBPM methods and that from HBPM was analyzed using the Bland-Altman plot. The change in the proportion of each BP phenotype was also analyzed.\u0000Results: We included 114 participants. The mean age was 57.96 + 15.07 years. The average BP from attended AOBPM, unattended AOBPM, and HBPM were 150.52 + 16.12/81.77 + 11.04, 139.68 + 13.80/78.55 + 11.71, and 126.91 + 9.80/76.40 + 8.37 mmHg, respectively. The BP and heart rate measured by these techniques were significantly different (p-value of <0.001). Bland-Altman analysis showed the biases of attended and unattended SBP versus home SBP were 23.61 and 12.77 mmHg, respectively. Unattended AOBPM significantly decreased the numbers of patients classified as white-coat and sustained hypertension regardless of BP thresholds (p-value of <0.001 for both groups).\u0000Conclusion: Unattended AOBPM significantly minimizes the white-coat effect in real-life clinical practice and may help physicians avoid overdiagnosis of hypertension. Nevertheless, it does not replace HBPM.","PeriodicalId":37270,"journal":{"name":"Siriraj Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49585267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-01DOI: 10.33192/smj.v75i6.261710
R. Ruangtrakool, Piyaporn Krajangjit
Objective: The purpose of this study was to examine factors affecting early complications following transanal endorectal pull-through (TERPT) in patients with Hirschprung’s disease. Materials and Methods: Retrospective chart reviews of patients with Hirschsprung’s disease who underwent TERPT/ abdominal assisted TERPT at Siriraj Hospital between January 2009 and December 2019 was carried out. . Results: The overall complication rate was 26% (43/163). The complications were as follows: 14 cases of anastomotic strictures (32.6%), five cases of abscess at anastomosis (11.6%), and three cases of anastomotic leakages (7.0%). In regards to preoperative bowel preparation, when comparing those with and those without post-operative complications, the amount of NSS for rectal irrigation (ml/Kg), duration required (days), and duration of changed diet (days) were the same. Colostomy prior to a pull-through operation could not prevent post-operative complications following endorectal pull-through (p = 1.000). The incidences of early complications following TERPT and abdominal assisted TERPT was the same (p = 0.344). Abdominal assisted TERPT had a higher incidence (4%) of anastomotic leakages whereas TERPT had a higher rate of anastomosis strictures (12%) compared to o abdominal assisted TERPT (5%). The higher the transitional zone, the higher the complication rate. Anastomotic leakages, the most serious complication, rarely occurred following TERPT in the low transitional zone. Conclusion: There was no significant risk factor associated with early surgical complications following TERPT. Abdominal assisted TERPT should be selected properly according to the level of transitional zone. The complications correlate with whether a perfect pull-through operation could be performed or not.
{"title":"Early Surgical Complications Following Transanal Endorectal Pull-through for Hirschsprung’s Disease","authors":"R. Ruangtrakool, Piyaporn Krajangjit","doi":"10.33192/smj.v75i6.261710","DOIUrl":"https://doi.org/10.33192/smj.v75i6.261710","url":null,"abstract":"Objective: The purpose of this study was to examine factors affecting early complications following transanal endorectal pull-through (TERPT) in patients with Hirschprung’s disease.\u0000Materials and Methods: Retrospective chart reviews of patients with Hirschsprung’s disease who underwent TERPT/ abdominal assisted TERPT at Siriraj Hospital between January 2009 and December 2019 was carried out. .\u0000Results: The overall complication rate was 26% (43/163). The complications were as follows: 14 cases of anastomotic strictures (32.6%), five cases of abscess at anastomosis (11.6%), and three cases of anastomotic leakages (7.0%). In regards to preoperative bowel preparation, when comparing those with and those without post-operative complications, the amount of NSS for rectal irrigation (ml/Kg), duration required (days), and duration of changed diet (days) were the same. Colostomy prior to a pull-through operation could not prevent post-operative complications following endorectal pull-through (p = 1.000). The incidences of early complications following TERPT and abdominal assisted TERPT was the same (p = 0.344). Abdominal assisted TERPT had a higher incidence (4%) of anastomotic leakages whereas TERPT had a higher rate of anastomosis strictures (12%) compared to o abdominal assisted TERPT (5%). The higher the transitional zone, the higher the complication rate. Anastomotic leakages, the most serious complication, rarely occurred following TERPT in the low transitional zone.\u0000Conclusion: There was no significant risk factor associated with early surgical complications following TERPT. Abdominal assisted TERPT should be selected properly according to the level of transitional zone. The complications correlate with whether a perfect pull-through operation could be performed or not.","PeriodicalId":37270,"journal":{"name":"Siriraj Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43880231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-01DOI: 10.33192/smj.v75i6.261925
Tanapat Pansaksiri, Patranuch Noppakulsatid
Objective: Our objective was to determine how effectively our smartphone app improved follow-up compliance in ureteral stent patients. Materials and Methods: Two groups of patients who underwent double-j stent placement were compared. For the traditional program (i), retrospective data from January 2021 to June 2021 was collected. We randomly selected 72 patients from the overall 121 patient data. For the smartphone-based stent tracking program (ii), a smartphone application was used from July 2022 to January 2023 to track 72 patients. Result: The rate of poor compliance in group (ii) (4.2%), was significantly lower (p=0.004) than the rate of poor compliance in group (i) (19.4%). Differences in diagnosis between the two groups were not found to be related to the compliance rates. Surprisingly, kidney transplant patients in both groups had perfect compliance. Conclusion: Smartphone-based stent tracking application increased patient compliance to appointments in patients who underwent double-j stent placement. This study is a demonstration of how technology can assist patients to better health care and can prevent complications.
{"title":"Efficacy Evaluation of Smartphone-based Stent Tracking Application in Follow-up Patients with Ureteral Stents: A Prospective Study","authors":"Tanapat Pansaksiri, Patranuch Noppakulsatid","doi":"10.33192/smj.v75i6.261925","DOIUrl":"https://doi.org/10.33192/smj.v75i6.261925","url":null,"abstract":"Objective: Our objective was to determine how effectively our smartphone app improved follow-up compliance in ureteral stent patients.\u0000Materials and Methods: Two groups of patients who underwent double-j stent placement were compared. For the traditional program (i), retrospective data from January 2021 to June 2021 was collected. We randomly selected 72 patients from the overall 121 patient data. For the smartphone-based stent tracking program (ii), a smartphone application was used from July 2022 to January 2023 to track 72 patients.\u0000Result: The rate of poor compliance in group (ii) (4.2%), was significantly lower (p=0.004) than the rate of poor compliance in group (i) (19.4%). Differences in diagnosis between the two groups were not found to be related to the compliance rates. Surprisingly, kidney transplant patients in both groups had perfect compliance. \u0000Conclusion: Smartphone-based stent tracking application increased patient compliance to appointments in patients who underwent double-j stent placement. This study is a demonstration of how technology can assist patients to better health care and can prevent complications.","PeriodicalId":37270,"journal":{"name":"Siriraj Medical Journal","volume":"101 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69524984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-01DOI: 10.33192/smj.v75i6.261621
P. Rojsanga, Anchalee Jintapattanakit, D. Chantasart
Objective: The aim of this study was to investigate the physicochemical and microbiological stability of extemporaneous amitriptyline hydrochloride (AMH) topical preparations for the treatment of neuropathic pain. Materials and Methods: AMH tablets were triturated to produce fine powders with a mortar and pestle. These powders were levigated and separately incorporated into four compounding bases: hydrophilic petrolatum USP, anionic cream, cold cream USP, and pluronic lecithin organogel (PLO) having the concentration of 2%w/w AMH. Results: In the in vitro release study, the most significant amount of AMH was released from the PLO, followed by cold cream, anionic cream and hydrophilic petrolatum, respectively; therefore, the compounded AMH in cold cream and AMH in PLO were selected for the evaluation of the in vitro permeation and product stability. The permeation of AMH from PLO across human epidermal membrane was significantly greater than that from the cold cream.Product stability was characterized as having no remarkable change in color or texture and AMH remaining in the range of 90–110% of the initial concentration quantified by high-performance liquid chromatography. Compounded AMH in cold cream was stable at 2–8 °C and 30 °C for 60 days, and 40 °C for 30 days, whereas compounded AMH in PLO was stable at 30 °C and 40 °C for 14 days. There was no visible microbial growth in any of the samples. Conclusion: Taken together with the in vitro permeation and product stability studies, the present study suggests that AMH in cold cream could be prepared and used as extemporaneous topical preparations with a beyond-use date of 60 days when kept at 2–8 °C and 30 °C.
{"title":"Stability of Extemporaneously Prepared Amitriptyline Hydrochloride Topical Preparations for the Treatment of Neuropathic Pain","authors":"P. Rojsanga, Anchalee Jintapattanakit, D. Chantasart","doi":"10.33192/smj.v75i6.261621","DOIUrl":"https://doi.org/10.33192/smj.v75i6.261621","url":null,"abstract":"Objective: The aim of this study was to investigate the physicochemical and microbiological stability of extemporaneous amitriptyline hydrochloride (AMH) topical preparations for the treatment of neuropathic pain.\u0000Materials and Methods: AMH tablets were triturated to produce fine powders with a mortar and pestle. These powders were levigated and separately incorporated into four compounding bases: hydrophilic petrolatum USP, anionic cream, cold cream USP, and pluronic lecithin organogel (PLO) having the concentration of 2%w/w AMH.\u0000Results: In the in vitro release study, the most significant amount of AMH was released from the PLO, followed by cold cream, anionic cream and hydrophilic petrolatum, respectively; therefore, the compounded AMH in cold cream and AMH in PLO were selected for the evaluation of the in vitro permeation and product stability. The permeation of AMH from PLO across human epidermal membrane was significantly greater than that from the cold cream.Product stability was characterized as having no remarkable change in color or texture and AMH remaining in the range of 90–110% of the initial concentration quantified by high-performance liquid chromatography. Compounded AMH in cold cream was stable at 2–8 °C and 30 °C for 60 days, and 40 °C for 30 days, whereas compounded AMH in PLO was stable at 30 °C and 40 °C for 14 days. There was no visible microbial growth in any of the samples.\u0000Conclusion: Taken together with the in vitro permeation and product stability studies, the present study suggests that AMH in cold cream could be prepared and used as extemporaneous topical preparations with a beyond-use date of 60 days when kept at 2–8 °C and 30 °C.","PeriodicalId":37270,"journal":{"name":"Siriraj Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47420456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: To demonstrate the outcome of transvaginal urethrolysis as a treatment option for women with recurrent cystitis, which could be caused from voiding problems. In the case of a failure of non-invasive treatment, the surgical procedure to decrease outlet resistance may have a role. Materials and Methods: Between January 2016 and December 2020, women with recurrent cystitis who underwent urethrolysis at Siriraj Hospital were retrospectively reviewed. Only women who were followed-up for more than 6 months were analyzed. Cure was defined by no clinical symptoms of cystitis, no pyuria on urine analysis, and/or negative urine culture during the follow-up period. Results: In total, 52 women underwent transvaginal urethrolysis. The overall cure rate was observed 53.9% (28 cases) at a median follow-up time of 11.9 (6–59) months. Eighteen of the 44 cases (40.9%) who underwent a video urodynamics study showed bladder outlet obstruction, defined as a Solomon–Greenwell bladder outlet obstruction index of more than 5. None of the characteristics or urodynamics parameters showed statistically significant differences between the cure and failure groups. Postoperative urinary incontinence was reported in 14 cases (26.9%) but showed no statistical difference between the cure and failure group (p = 0.748). Conclusion: Bladder outlet obstruction is a common cause of recurrent cystitis. Transvaginal urethrolysis may have a role as treatment for women with recurrent cystitis from voiding dysfunction who have failed non- and less-invasive treatments. Here, the overall cure rate was 53.8%. A factor associated with the cure rate could not be demonstrated in this study.
{"title":"Transvaginal Urethrolysis As A Treatment Option For Women With Recurrent Cystitis","authors":"Sunporn Boonwong, Atichet Sawangchareon, Patkawat Ramart","doi":"10.33192/smj.v75i5.261230","DOIUrl":"https://doi.org/10.33192/smj.v75i5.261230","url":null,"abstract":"Objectives: To demonstrate the outcome of transvaginal urethrolysis as a treatment option for women with recurrent cystitis, which could be caused from voiding problems. In the case of a failure of non-invasive treatment, the surgical procedure to decrease outlet resistance may have a role.\u0000Materials and Methods: Between January 2016 and December 2020, women with recurrent cystitis who underwent urethrolysis at Siriraj Hospital were retrospectively reviewed. Only women who were followed-up for more than 6 months were analyzed. Cure was defined by no clinical symptoms of cystitis, no pyuria on urine analysis, and/or negative urine culture during the follow-up period.\u0000Results: In total, 52 women underwent transvaginal urethrolysis. The overall cure rate was observed 53.9% (28 cases) at a median follow-up time of 11.9 (6–59) months. Eighteen of the 44 cases (40.9%) who underwent a video urodynamics study showed bladder outlet obstruction, defined as a Solomon–Greenwell bladder outlet obstruction index of more than 5. None of the characteristics or urodynamics parameters showed statistically significant differences between the cure and failure groups. Postoperative urinary incontinence was reported in 14 cases (26.9%) but showed no statistical difference between the cure and failure group (p = 0.748).\u0000Conclusion: Bladder outlet obstruction is a common cause of recurrent cystitis. Transvaginal urethrolysis may have a role as treatment for women with recurrent cystitis from voiding dysfunction who have failed non- and less-invasive treatments. Here, the overall cure rate was 53.8%. A factor associated with the cure rate could not be demonstrated in this study.","PeriodicalId":37270,"journal":{"name":"Siriraj Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42978313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.33192/smj.v75i5.261536
Suveerawan Limsuvan, Titchaphorn Palo, Dollaporn Mamaethong, Nut Yuthanarat, Suksalin Booranasubkajorn, N. Lumlerdkij, Kamonchanok Maneechai, P. Akarasereenont
Objective: To investigate the effects of the WNF on platelet aggregation and find a link between iDCR factors and platelet aggregation. Materials and Methods: Forty healthy volunteers with different iDCRs (Earth, Water, Wind, and Fire) received a single dose of 1,000 mg WNF. A blood sample was taken before and after the WNF administration at 3, 6, and 24 hours for analysis of platelet aggregation by aggregometry. Epinephrine, adenosine diphosphate (ADP) and collagen were used as platelet agonists. Results: The WNF affects platelet aggregation in some subjects, especially females with an Earth iDCR or Wind iDCR with hyperaggregation patterns at baseline. The result after WNF treatment revealed that the percentage of platelet aggregation significantly changed downward at 3 hours and then recovered to pre-dosing levels after 24 hours. Additionally, it also did not have any relationship to iDCR. There were no reported adverse drug events. Conclusion: WNF should be used with caution in patients with blood diseases and a close eye should be kept on herb-drug interactions such as with aspirin or other NSAIDs.
{"title":"The Effect of The Thai Herbal Wattana Formula on Platelet Aggregation and The Relationship with Innate Dhatu Chao Ruean","authors":"Suveerawan Limsuvan, Titchaphorn Palo, Dollaporn Mamaethong, Nut Yuthanarat, Suksalin Booranasubkajorn, N. Lumlerdkij, Kamonchanok Maneechai, P. Akarasereenont","doi":"10.33192/smj.v75i5.261536","DOIUrl":"https://doi.org/10.33192/smj.v75i5.261536","url":null,"abstract":"Objective: To investigate the effects of the WNF on platelet aggregation and find a link between iDCR factors and platelet aggregation.\u0000Materials and Methods: Forty healthy volunteers with different iDCRs (Earth, Water, Wind, and Fire) received a single dose of 1,000 mg WNF. A blood sample was taken before and after the WNF administration at 3, 6, and 24 hours for analysis of platelet aggregation by aggregometry. Epinephrine, adenosine diphosphate (ADP) and collagen were used as platelet agonists.\u0000Results: The WNF affects platelet aggregation in some subjects, especially females with an Earth iDCR or Wind iDCR with hyperaggregation patterns at baseline. The result after WNF treatment revealed that the percentage of platelet aggregation significantly changed downward at 3 hours and then recovered to pre-dosing levels after 24 hours. Additionally, it also did not have any relationship to iDCR. There were no reported adverse drug events.\u0000Conclusion: WNF should be used with caution in patients with blood diseases and a close eye should be kept on herb-drug interactions such as with aspirin or other NSAIDs.","PeriodicalId":37270,"journal":{"name":"Siriraj Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46302756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.33192/smj.v75i5.260948
Sangarun Dungkong
Achilles tendinopathy (AT) is common in both the general population and athletes, especially in running and jumping sports. The incidence of AT is 43% in athletes, but as high as 83% in middle-distance runners. However, 30% of patients have a sedentary lifestyle. Currently, the physical therapy (PT) is an effective conservative treatment and more widely population. Objective this review article is update the most effective physiotherapy treatment and the most validity and reliability clinical evaluation for AT. Destination is to provide physical therapist guideline for select appropriate clinical practice. The results of the literature review found that key treatment recommendation for AT is to follow an eccentric exercise protocol, which is the most common intervention for the management of functional limitations in AT. Extracorporeal shockwave therapy (ESWT) is the most commonly used next step when patients do not respond to eccentric exercise. Also, eccentric exercise combined with ESWT and eccentricexercise combined with ankle joint mobilization can improve immediately enhance their quality of life more than either treatment alone. Clinical evaluation can utilize many tools but the VISA-A questionnaire was developed as a validity and reliability assessment for AT. A limitation of the VISA-A questionnaire is that it was designed for athletes only, and so is inappropriate for the general population. The FAOS questionnaire has been accepted as a valid and reliable tool for evaluating foot and ankle injuries. Clinical evaluation is recommended to choosethe appropriate assessment tool each patient (for the general population or athletes).
{"title":"Current Physical Therapy Management and Clinical Evaluation for Achilles Tendinopathy","authors":"Sangarun Dungkong","doi":"10.33192/smj.v75i5.260948","DOIUrl":"https://doi.org/10.33192/smj.v75i5.260948","url":null,"abstract":"Achilles tendinopathy (AT) is common in both the general population and athletes, especially in running and jumping sports. The incidence of AT is 43% in athletes, but as high as 83% in middle-distance runners. However, 30% of patients have a sedentary lifestyle. Currently, the physical therapy (PT) is an effective conservative treatment and more widely population. Objective this review article is update the most effective physiotherapy treatment and the most validity and reliability clinical evaluation for AT. Destination is to provide physical therapist guideline for select appropriate clinical practice. The results of the literature review found that key treatment recommendation for AT is to follow an eccentric exercise protocol, which is the most common intervention for the management of functional limitations in AT. Extracorporeal shockwave therapy (ESWT) is the most commonly used next step when patients do not respond to eccentric exercise. Also, eccentric exercise combined with ESWT and eccentricexercise combined with ankle joint mobilization can improve immediately enhance their quality of life more than either treatment alone. Clinical evaluation can utilize many tools but the VISA-A questionnaire was developed as a validity and reliability assessment for AT. A limitation of the VISA-A questionnaire is that it was designed for athletes only, and so is inappropriate for the general population. The FAOS questionnaire has been accepted as a valid and reliable tool for evaluating foot and ankle injuries. Clinical evaluation is recommended to choosethe appropriate assessment tool each patient (for the general population or athletes).","PeriodicalId":37270,"journal":{"name":"Siriraj Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46886961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.33192/smj.v75i5.261510
E. Chotikawanich, S. Leewansangtong, Karn Liangkobkit, C. Nualyong, S. Srinualnad, B. Chaiyaprasithi, T. Taweemonkongsap, Kittipong Phinthusophon, S. Jitpraphai, Patkawat Ramart, V. Woranisarakul, C. Suk-ouichai, Thawatchai Mankongsrisuk, T. Hansomwong, Kantima Jongjitaree
Objective: To study the safety and efficacy of retrograde intrarenal surgery (RIRS) in patients with staghorn stones. Materials and Methods: This retrospective observational study was carried out between May 2016 and October 2020, which is when we performed RIRS in staghorn stone patients. Medical records of all patients with this condition in the database of Siriraj Hospital were reviewed. A total of 35 patients were eligible for this study. Descriptive statistics were used to assess the safety and efficacy of RIRS in patients with staghorn stones. Results: In total, 31.43% of patients were stone-free after the first round of RIRS and 59.55% achieved stone-free status after the second procedure. The stone-free rate did not increase after a second round of RIRS. The median size of all staghorn stones was 3.1 cm. Unfortunately, we found two sepsis patients in this study. We also found eight events of minor complications, including fever and minimal ureteric injury in 54 sessions of RIRS we performed. However, no major injuries or bleeding requiring blood transfusion was identified. Conclusion: Percutaneous nephrolithotomy (PCNL) is still considered the first-line therapy for kidney stones over two centimeters with a favorable stone-free rate. But, in some patients with limitations such as uncorrectable coagulopathies, impaired renal function, single kidney, and morbid obesity, RIRS is a good choice to reduce the likelihood of serious complications and have an acceptable stone-free rate. However, a prospective study should be performed to confirm these findings.
{"title":"The Feasibility and Outcomes of Retrograde Intrarenal Surgery to Treat Staghorn Renal Calculi","authors":"E. Chotikawanich, S. Leewansangtong, Karn Liangkobkit, C. Nualyong, S. Srinualnad, B. Chaiyaprasithi, T. Taweemonkongsap, Kittipong Phinthusophon, S. Jitpraphai, Patkawat Ramart, V. Woranisarakul, C. Suk-ouichai, Thawatchai Mankongsrisuk, T. Hansomwong, Kantima Jongjitaree","doi":"10.33192/smj.v75i5.261510","DOIUrl":"https://doi.org/10.33192/smj.v75i5.261510","url":null,"abstract":"Objective: To study the safety and efficacy of retrograde intrarenal surgery (RIRS) in patients with staghorn stones.\u0000Materials and Methods: This retrospective observational study was carried out between May 2016 and October 2020, which is when we performed RIRS in staghorn stone patients. Medical records of all patients with this condition in the database of Siriraj Hospital were reviewed. A total of 35 patients were eligible for this study. Descriptive statistics were used to assess the safety and efficacy of RIRS in patients with staghorn stones.\u0000Results: In total, 31.43% of patients were stone-free after the first round of RIRS and 59.55% achieved stone-free status after the second procedure. The stone-free rate did not increase after a second round of RIRS. The median size of all staghorn stones was 3.1 cm. Unfortunately, we found two sepsis patients in this study. We also found eight events of minor complications, including fever and minimal ureteric injury in 54 sessions of RIRS we performed. However, no major injuries or bleeding requiring blood transfusion was identified.\u0000Conclusion: Percutaneous nephrolithotomy (PCNL) is still considered the first-line therapy for kidney stones over two centimeters with a favorable stone-free rate. But, in some patients with limitations such as uncorrectable coagulopathies, impaired renal function, single kidney, and morbid obesity, RIRS is a good choice to reduce the likelihood of serious complications and have an acceptable stone-free rate. However, a prospective study should be performed to confirm these findings.","PeriodicalId":37270,"journal":{"name":"Siriraj Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46272399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}