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Readmission Rate of Outpatient Distal Radius Fixation Surgery with Brachial Plexus Block and Midline Pronator Quadratus Approach in the COVID-19 Era: A Retrospective Case Series Report in a Secondary Care Hospital in Thailand 新冠肺炎时代臂丛阻滞和中前屈二次肌入路门诊桡骨远端固定手术的再手术率:泰国一家二级护理医院的回顾性病例系列报告
Q3 Medicine Pub Date : 2023-07-01 DOI: 10.33192/smj.v75i7.262700
C. Mahaisavariya, Chuthamas Puengtananukij, Anticha Siritongtaworn
Objective: To demonstrate the readmission rate after distal radius fixation surgery performed with a brachial plexus block and the midline pronator quadratus approach in an ambulatory manner in a secondary care hospital.Materials and Methods: This retrospective study analyzed data on distal radius fracture patients treated with ambulatory surgery. The patients were enrolled from 1 January 2020 to 28 February 2022, which was during the COVID-19 pandemic. The primary outcome was the readmission rate within 30 days after the surgery. The secondary outcomes were complications, postoperative pain, radiographic outcome, and functional score. All patients were followed up for at least 1 year after the surgery.Results: Thirty-one patients were enrolled in this study. Their mean age was 58.5 years, and the fractures were mainly caused by low-energy trauma. No postoperative complications were reported, and no readmission after surgery was observed. Overall radiographic parameters were in the acceptable range (radial inclination = 21.9, radial height = 10.26, volar tilt = 2.65, and ulna variance = 1.33). All patients returned to their preinjury statuses within 5 months.Conclusion: Distal radius fixation surgery can be managed in an ambulatory manner with a low readmission rate, even in secondary care hospitals. This repair technique provides adequate soft tissue coverage of the volar radius plate while decreasing the risk of iatrogenic radial artery injuries.
目的:证明在二级护理医院采用臂丛神经阻滞和旋前象限中线入路进行桡骨远端固定手术后的再入院率。材料和方法:本回顾性研究分析了桡骨远端骨折患者接受门诊手术治疗的数据。患者于2020年1月1日至2022年2月28日登记,这是在新冠肺炎大流行期间。主要结果是手术后30天内的再次入院率。次要结果为并发症、术后疼痛、放射学结果和功能评分。所有患者术后均进行了至少1年的随访。结果:31名患者被纳入本研究。平均年龄58.5岁,骨折主要由低能量创伤引起。没有术后并发症的报告,也没有观察到术后再次入院。总体放射学参数在可接受范围内(径向倾斜度=21.9,径向高度=10.26,掌侧倾斜度=2.65,尺骨方差=1.33)。所有患者在5个月内恢复到损伤前状态。结论:即使在二级护理医院,桡骨远端固定手术也可以以门诊方式进行,再入院率低。这种修复技术为桡骨掌侧钢板提供了足够的软组织覆盖,同时降低了医源性桡动脉损伤的风险。
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引用次数: 0
Effectiveness of Repetitive Peripheral Magnetic Stimulation for Treatment of Mild to Moderate Carpal Tunnel Syndrome: A Randomized Controlled Trial 重复性外周磁刺激治疗轻中度腕管综合征的疗效:一项随机对照试验
Q3 Medicine Pub Date : 2023-07-01 DOI: 10.33192/smj.v75i7.262387
Thong Phonghanyudh, Kanintat Senchantichai, Natchaya Kaewma, Chanwit Phongamwong
Objective: This study aimed to evaluate the effectiveness of active repetitive peripheral magnetic stimulation (rPMS) compared to sham rPMS on symptoms severity and functional status among patients with mild to moderate carpal tunnel syndrome.Materials and Methods: A randomized controlled trial was conducted. Participants were randomly allocated (1:1) to either intervention (active rPMS) or control (sham rPMS) groups. Both groups received rPMS (A20 mode of OPTIMUS Pro) for 10 min, once a week for four weeks (four sessions). Symptom severity scales (SSS) and functional status scales (FSS) of Boston Carpal Tunnel Questionnaire were measured at baseline (before session one) and at the end of treatment (after session four). The relative changes in SSS and FSS scores were calculated as a clinical outcome.Results: Forty-two participants were enrolled and randomly allocated to either the intervention (n = 21) or control group (n = 21). There were no statistically significant differences in the median (interquartile range) of relative changes in SSS [0.05 (0.15) vs 0 (0.27), P = 0.41] or FSS [0 (0.25) vs 0 (0.11), P = 0.97] between the intervention and control groups.Conclusion: Active rPMS did not improve clinical outcome compared to sham rPMS among patients with mild to moderate CTS. A greater number of subjects and treatment sessions might be required for the future study.
目的:本研究旨在评价主动重复外周磁刺激(rPMS)与假rPMS对轻至中度腕管综合征患者症状严重程度和功能状态的影响。材料与方法:采用随机对照试验。参与者被随机分配(1:1)到干预组(积极rPMS)或对照组(假rPMS)组。两组均接受rPMS (OPTIMUS Pro的A20模式)治疗,每次10分钟,每周1次,共4周(4次)。在基线(第一阶段前)和治疗结束(第四阶段后)分别测量波士顿腕管问卷症状严重程度量表(SSS)和功能状态量表(FSS)。计算SSS和FSS评分的相对变化作为临床结果。结果:42名参与者被纳入并随机分配到干预组(n = 21)和对照组(n = 21)。干预组与对照组SSS相对变化的中位数(四分位数范围)[0.05 (0.15)vs 0 (0.27), P = 0.41]和FSS [0 (0.25) vs 0 (0.11), P = 0.97]差异均无统计学意义。结论:在轻中度CTS患者中,与假rPMS相比,主动rPMS并没有改善临床结果。未来的研究可能需要更多的受试者和治疗疗程。
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引用次数: 0
Eating Disorders and their Relation with Emotional Disturbances among Undergraduate Students in Malaysia during COVID-19 Pandemic 新冠肺炎大流行期间马来西亚大学生饮食失调及其与情绪障碍的关系
Q3 Medicine Pub Date : 2023-07-01 DOI: 10.33192/smj.v75i7.262003
G. Faisal, A. Radeef, O. Ibrahim
Objective: COVID-19 pandemic has greatly impacted several aspects of undergraduate students’ lives including significant effect on mental wellbeing, physical activity and eating habits which might increase the risk for developing eating disorders as these disorders tend to emerge at university age. This study aimed to assess the prevalence of eating disorders and their associated factors among undergraduate students.Materials and Methods: A cross sectional study was conducted among 624 undergraduate students from three different universities in Malaysia. Eating disorders was assessed using the Malay version of the Eating Disorder Examination Questionnaire (EDE-Q) while the emotional disturbances was assessed by the Malay version of Kessler Psychological Distress Scale (K10) and perceived social support was assessed by the revised Malay version of The 8-item Multidimensional Scale of Perceived Social Support (MSPSS).Results: The prevalence of eating disorders among students was 14.9%. There were significant differences in terms of gender and other socio-demographic factors. Eating disorders were significantly associated and positively correlated with emotional disturbances level r = 0.37. While inverse correlation between social support and eating disorders was also shown r= -0.13. Multiple linear regression analysis showed that emotional disturbances level (β = 0.212, P = 0.000) and poor social support (β = -0.126, P = 0.002) were a significantly important risk factor.Conclusion: Eating disorders are prevalent among undergraduate students, female students, emotional disturbances and high BMI are significantly associated factors. Emotional disturbances and poor social support are predictive factor for eating disorders.
目的:2019冠状病毒病大流行极大地影响了大学生生活的几个方面,包括对心理健康、身体活动和饮食习惯的重大影响,这可能会增加患饮食失调的风险,因为这些疾病往往出现在大学年龄。本研究旨在评估大学生饮食失调的患病率及其相关因素。材料与方法:对来自马来西亚三所不同大学的624名本科生进行横断面研究。进食障碍采用马来语版进食障碍检查问卷(ed - q)进行评估,情绪障碍采用马来语版凯斯勒心理困扰量表(K10)进行评估,感知社会支持采用马来语版8项感知社会支持多维量表(MSPSS)进行评估。结果:学生饮食失调患病率为14.9%。在性别和其他社会人口因素方面存在显著差异。饮食失调与情绪障碍呈显著正相关,水平r = 0.37。而社会支持与饮食失调也呈负相关,r= -0.13。多元线性回归分析结果显示,情绪障碍水平(β = 0.212, P = 0.000)和社会支持不良(β = -0.126, P = 0.002)是影响抑郁的重要因素。结论:进食障碍在大学生中普遍存在,女大学生、情绪障碍和高BMI是进食障碍的显著相关因素。情绪障碍和缺乏社会支持是饮食失调的预测因素。
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引用次数: 0
Social Support in Quality of Life among Breast Cancer Patients after Diagnosis: A Bibliometric Analysis 社会支持对乳腺癌患者诊断后生活质量的影响:文献计量学分析
Q3 Medicine Pub Date : 2023-07-01 DOI: 10.33192/smj.v75i7.261979
Solikhah Solikhah, D. Perwitasari, Lalu Muhammad Irham, Ratu Matahari
In terms of bibliometric analysis, there are no studies related to the impact of social support on breast cancer survivors' quality of life. Therefore, this study aims to provide a bibliometric assessment of results on social support in quality of life in breast cancer patients. The studies for the dataset were selected from Scopus published in the year 2001–2021 based on their relevancy to the established subjects. The VOSviewer software was used for bibliometric analysis to represent the performance of publications covering annual outputs, mainstream journals leading countries, institutions, research tendencies, and hotspots. The analysis of the findings indicated only 45 articles over the range of 2001-2021. The highest number of publications was published in 2021, and the lowest was in 2002-2004 and 2006. Social support strongly correlates with the psychological adjustment of adherence to cancer treatment. Only one study failed to find an association between social support and suicide after a cancer diagnosis. Meanwhile, China, the United States, and Hong Kong contributed to social support. Instrumental, financial, information, and emotional support were reported as domains needed to support breast cancer patients. This bibliometric analysis provides the results of thoughts and insights about the development needed by breast cancer patients to prolong survival.
在文献计量分析方面,没有研究表明社会支持对癌症幸存者生活质量的影响。因此,本研究旨在对癌症患者生活质量社会支持的结果进行文献计量评估。该数据集的研究是根据其与既定受试者的相关性从2001-2021年发表的Scopus中选择的。VOSviewer软件用于文献计量分析,以表示出版物的表现,包括年度产出、主流期刊、领先国家、机构、研究趋势和热点。对调查结果的分析表明,在2001-2021年间,只有45篇文章。出版数量最多的是2021年,最低的是2002-2004年和2006年。社会支持与坚持癌症治疗的心理调整密切相关。只有一项研究未能发现社会支持与癌症诊断后自杀之间的联系。同时,中国、美国和香港为社会支持做出了贡献。据报道,工具、财务、信息和情感支持是支持癌症患者所需的领域。这篇文献计量分析提供了对癌症患者延长生存期所需的发展的思考和见解的结果。
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引用次数: 1
Patients’ Need for Sexual Counseling in the Cardiac Rehabilitation Service 心脏康复服务中患者对性咨询的需求
Q3 Medicine Pub Date : 2023-07-01 DOI: 10.33192/smj.v75i7.263195
Pattarika Rittirong, Wilawan Thirapatarapong, Thanitta Thanakiatpinyo
Objective: To evaluate the need for sexual counseling among patients with heart diseaseMaterials and Methods: Data were collected from 363 patients with heart disease attending a cardiac rehabilitation outpatient clinic. Participants completed the questionnaire independently.Results: The participants consisted of 241 males (66.4%) and 122 females (33.6%) with a mean age of 57.69±14.50 years. Among them, 248 (68.3%) were married. Most participants (91.2%) agreed that healthcare providers should offer sexual counseling to all heart patients of reproductive age, and they wanted their healthcare providers to initiate the counseling. Factors related to the need for counseling were being male (OR=2.07; 95% CI =1.05-4.07), being married (OR=2.04; 95% CI =1.03-4.05) and being 50 years of age or younger (OR 9.05; 95%CI =2.06-39.82). The main obstacles affecting conversations about sexual activity with healthcare providers were feeling embarrassed (45.7%), being physically impaired (45.4%), and having a third person present during counseling (44.9%).Conclusion: Most patients with heart disease want to receive counseling on how to safely resume sexual activity following their illness. They expect healthcare providers to initiate such counseling during visits to cardiac rehabilitation clinics. It is crucial that healthcare providers provide counseling in a format that is tailored to the needs and preferences of each patient.  
目的:评估心脏病患者对性咨询的需求材料和方法:收集363名心脏病康复门诊患者的数据。参与者独立完成问卷调查。结果:参与者包括241名男性(66.4%)和122名女性(33.6%),平均年龄为57.69±14.50岁。其中已婚248人(68.3%)。大多数参与者(91.2%)同意医疗保健提供者应该为所有育龄心脏病患者提供性咨询,他们希望他们的医疗保健提供者发起咨询。与咨询需求相关的因素是男性(OR=2.07;95%CI=1.05-4.07)、已婚(OR=2.04;95%CI-1.03-4.05)和50岁或50岁以下(OR9.05;95%CI=2.06-39.82)。影响与医疗保健提供者谈论性活动的主要障碍是感到尴尬(45.7%)、身体受损(45.4%),以及在咨询过程中有第三人在场(44.9%)。结论:大多数心脏病患者希望接受关于如何在患病后安全地恢复性活动的咨询。他们希望医疗保健提供者在去心脏康复诊所就诊时主动提供此类咨询。至关重要的是,医疗保健提供者应根据每位患者的需求和偏好提供量身定制的咨询服务。
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引用次数: 1
Prevalence and Factors Associated with Post-operative Strictures in Anorectal Malformations 肛门直肠畸形术后狭窄的患病率及相关因素
Q3 Medicine Pub Date : 2023-07-01 DOI: 10.33192/smj.v75i7.262816
R. Ruangtrakool, Thuphom Chodchoy
Objective: Rectal strictures are a serious complication following operation for anorectal malformations (ARM). The purpose of this study was to determine the factors affecting rectal strictures following surgical treatments for ARM.Materials and Methods: Retrospective chart reviews of 204 patients with ARM who underwent surgical treatment at Siriraj Hospital between January 2003 and December 2019 were carried out.Results: Overall, the prevalence of post-operative rectal stricture was 19.6% (40/204). The higher types of ARM had higher rectal stricture rates.  In low type ARM, the stricture rate following surgery for perineal fistula, vestibular fistula was 4.1% and 14.7%, respectively. Recto-bulbar urethral fistula and recto-prostatic urethral fistula had stricture rates of 19.2% and 26.7%, respectively, but in higher types, the stricture rates were above 70%. Complications such as wound infection, dehiscence, retraction, colonic necrosis and recurrent fistula all affected the post-operative stricture rate (p = 0.029, p = 0.01, p = 0.01, p = 0.042 and p = 0.002, respectively). The operation for low type ARM using local tissue flap, such as YV and cutback anoplasty, had low complications. More complicated operations were performed for higher type ARM. The higher the complication rate, the higher the post-operative rectal stricture. Routine rectal dilatation by parents seemed to prevent rectal strictures (p = 0.056). The surgical treatments for rectal strictures composed of 57.5% anoplasty, 17.5% PSARP, 15% abdo-assisted pull-through and 10% abdo-assisted PSARP.Conclusion: Post-operative rectal stricture occurred because of complications following complicated operations for high type ARM. A meticulous operative technique is crucial.
目的:直肠狭窄是肛门直肠畸形术后的一个严重并发症。本研究的目的是确定影响ARM手术治疗后直肠狭窄的因素。材料和方法:对2003年1月至2019年12月在Siriraj医院接受手术治疗的204名ARM患者进行回顾性图表审查。结果:总的来说,术后直肠狭窄的发生率为19.6%(40/204)。ARM类型越高,直肠狭窄发生率越高。在低型ARM中,会阴瘘、前庭瘘术后狭窄率分别为4.1%和14.7%。直肠球尿道瘘和直肠前列腺尿道瘘的狭窄率分别为19.2%和26.7%,但在较高类型中,狭窄率超过70%。伤口感染、裂开、回缩、结肠坏死和复发性瘘等并发症均影响术后狭窄率(分别为p=0.029、p=0.01、p=0.042和p=0.002)。应用局部组织瓣如YV和切口肛门成形术治疗低型ARM并发症少。对更高类型的ARM执行了更复杂的操作。并发症发生率越高,术后直肠狭窄程度越高。父母的常规直肠扩张似乎可以预防直肠狭窄(p=0.056)。直肠狭窄的手术治疗包括57.5%的肛门成形术、17.5%的PSARP、15%的腹部辅助牵引和10%的腹部辅助PSARP。细致的操作技巧至关重要。
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引用次数: 0
Effect of Multifocal Intraocular Lens on Contrast Sensitivity in Primary Angle-Closure Patients 多焦人工晶状体对原发性闭角症患者对比敏感度的影响
Q3 Medicine Pub Date : 2023-07-01 DOI: 10.33192/smj.v75i7.263254
Naris Kitnarong, Dovchinjamts Dagvadorj
Objective: To study the effect of multifocal intraocular lens (MIOL) implantation on contrast sensitivity (CS) compared to monofocal intraocular lens (mIOL) in primary angle-closure (PAC) or primary angle-closure glaucoma (PACG) patients. Materials and Methods: This prospective study included patients with PAC or PACG and visually significant cataract. Phacoemulsification with MIOL or mIOL (patient preference) was performed. Collected data included best-corrected distant visual acuity (BCVA), intraocular pressure (IOP), anterior chamber depth (ACD), and contrast sensitivity (CS) measured at spatial frequency 1.5, 3.0, 6.0, 12.0, and 18.0 cycles per degree (CPD) preoperatively, and at 2-6 months postoperatively. Preoperative and postoperative parameters were then compared. Results: Of the 45 eyes from 35 patients that were enrolled, 33 eyes (15 PAC, 18 PACG) from 26 patients completed the study. Fourteen eyes (11 patients) received diffractive MIOL, and 19 eyes (15 patients) received aspheric mIOL. Preoperative CS was not significantly different between groups. Postoperatively, BCVA, and CS at each spatial frequency were significantly improved in both groups (all p<0.001). Mean postoperative CS at spatial frequency 1.5, 3.0, 6.0, 12.0, and 18.0 CPD was 28.03, 42.63, 44.84, 10.82, and 2.86 in the MIOL group, and 29.55, 49.63, 46.20, 16.83, and 7.09 in the mIOL group, both respectively. Postoperative CS was not significant different between groups at any spatial frequencies. IOP was decreased (p=0.001) and ACD increased (p<0.001) postoperatively in both groups. Conclusion: No significant difference in visual acuity or contrast sensitivity was observed between MIOL and mIOL after cataract removal in patients with PAC/PACG.
目的:比较原发性闭角型青光眼(PAC)和原发性闭角型青光眼(PACG)患者多焦点人工晶状体(MIOL)植入术与单焦点人工晶状体(MIOL)对比敏感度(CS)的影响。材料与方法:本前瞻性研究纳入PAC或PACG合并显著性白内障患者。采用MIOL或MIOL(患者选择)进行超声乳化术。收集的数据包括术前和术后2-6个月在1.5、3.0、6.0、12.0和18.0周期/度(CPD)的空间频率下测量的最佳矫正远视力(BCVA)、眼内压(IOP)、前房深度(ACD)和对比敏感度(CS)。然后比较术前和术后参数。结果:在入选的35名患者的45只眼睛中,26名患者的33只眼睛(15只PAC, 18只PACG)完成了研究。衍射MIOL 14眼(11例),非球面MIOL 19眼(15例)。术前CS组间差异无统计学意义。两组术后各空间频率的BCVA和CS均显著改善(p < 0.001)。在空间频率1.5、3.0、6.0、12.0、18.0 CPD下,MIOL组术后平均CS分别为28.03、42.63、44.84、10.82、2.86;MIOL组术后平均CS分别为29.55、49.63、46.20、16.83、7.09。术后CS在各空间频率组间无显著差异。两组术后IOP降低(p=0.001), ACD升高(p=0.001)。结论:PAC/PACG患者摘除白内障后MIOL与MIOL的视力及对比敏感度无显著差异。
{"title":"Effect of Multifocal Intraocular Lens on Contrast Sensitivity in Primary Angle-Closure Patients","authors":"Naris Kitnarong, Dovchinjamts Dagvadorj","doi":"10.33192/smj.v75i7.263254","DOIUrl":"https://doi.org/10.33192/smj.v75i7.263254","url":null,"abstract":"Objective: To study the effect of multifocal intraocular lens (MIOL) implantation on contrast sensitivity (CS) compared to monofocal intraocular lens (mIOL) in primary angle-closure (PAC) or primary angle-closure glaucoma (PACG) patients. Materials and Methods: This prospective study included patients with PAC or PACG and visually significant cataract. Phacoemulsification with MIOL or mIOL (patient preference) was performed. Collected data included best-corrected distant visual acuity (BCVA), intraocular pressure (IOP), anterior chamber depth (ACD), and contrast sensitivity (CS) measured at spatial frequency 1.5, 3.0, 6.0, 12.0, and 18.0 cycles per degree (CPD) preoperatively, and at 2-6 months postoperatively. Preoperative and postoperative parameters were then compared. Results: Of the 45 eyes from 35 patients that were enrolled, 33 eyes (15 PAC, 18 PACG) from 26 patients completed the study. Fourteen eyes (11 patients) received diffractive MIOL, and 19 eyes (15 patients) received aspheric mIOL. Preoperative CS was not significantly different between groups. Postoperatively, BCVA, and CS at each spatial frequency were significantly improved in both groups (all p<0.001). Mean postoperative CS at spatial frequency 1.5, 3.0, 6.0, 12.0, and 18.0 CPD was 28.03, 42.63, 44.84, 10.82, and 2.86 in the MIOL group, and 29.55, 49.63, 46.20, 16.83, and 7.09 in the mIOL group, both respectively. Postoperative CS was not significant different between groups at any spatial frequencies. IOP was decreased (p=0.001) and ACD increased (p<0.001) postoperatively in both groups. Conclusion: No significant difference in visual acuity or contrast sensitivity was observed between MIOL and mIOL after cataract removal in patients with PAC/PACG.","PeriodicalId":37270,"journal":{"name":"Siriraj Medical Journal","volume":"288 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136184911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Neuroimaging Findings in Acquired Esotropia Patients at Siriraj Hospital from 2009–2020 2009-2020年Siriraj医院获得性内斜视患者的神经影像学发现
Q3 Medicine Pub Date : 2023-07-01 DOI: 10.33192/smj.v75i7.261478
Thammanoon Surachatkumtonekul, Natnicha Khiewwan, Kiatthida Hokierti, Piangporn Saksiriwuttho
Objective: To analyze the neuroimaging findings in patients with acquired esotropia at Siriraj Hospital from 2009 to 2020.Materials and Methods: A retrospective review of the medical records of all patients aged above 6 months old who presented with acquired esotropia was done. All the patients had an angle of deviation 10 prism diopters (PD), refraction < +3.0 diopters (D), and had neuroimaging performed. The patients with restrictive myopathy and extraocular neurological abnormalities were excluded from the study.Results: In total, 177 subjects aged between 8 months old to 81 years old (mean age 32.35 ± 24.40 years old) were included in the study. The patients’ demographic data, ocular findings, and neuroimaging findings were collected. The mean angle of deviation near and at distance were 26.88 ± 18.90 PD and 29.81 ± 17.25 PD, respectively. Of the 177 cases, 113 cases (63.8%) had no neuroimaging abnormalities, while 64 cases (36.2%) had abnormal neuroimaging findings. In those 64 cases with abnormal findings, there were 16 intracranial tumors, 6 inflammations, 4 vascular lesions, 7 degenerations, and 31 other lesions. Sixth nerve palsy was found to be significantly different between the positive and negative neuroimaging group from both the uni- and multivariate analysis.Conclusion: Although more than half of acquired esotropia patients had no abnormalities in neuroimaging, but 14.7% of those with abnormal neuroimaging findings had underlying serious conditions, which consisted of intracranial tumors, inflammation, and vascular lesions. Special attention should be concentrated to patients with sixth nerve palsy as it was the significant factor found to be associated with positive neuroimaging findings in acquired esotropia.
目的:分析2009 - 2020年诗丽拉杰医院获得性内斜视患者的神经影像学表现。材料与方法:回顾性分析所有年龄大于6个月的后天性内斜视患者的医疗记录。所有患者的偏角为棱镜屈光度10 (PD),屈光度< +3.0 (D),并行神经影像学检查。有限制性肌病和眼外神经异常的患者排除在研究之外。结果:共纳入受试者177例,年龄8月龄~ 81岁,平均年龄32.35±24.40岁。收集患者的人口学资料、眼部检查结果和神经影像学检查结果。近、远处平均偏角分别为26.88±18.90 PD和29.81±17.25 PD。177例患者中,113例(63.8%)未见神经影像学异常,64例(36.2%)有神经影像学异常。在64例异常中,颅内肿瘤16例,炎症6例,血管病变4例,变性7例,其他病变31例。从单因素和多因素分析中发现,阳性和阴性神经影像学组的第六神经麻痹有显著差异。结论:虽然超过一半的获得性内斜视患者神经影像学无异常,但14.7%的神经影像学异常患者存在潜在的严重疾病,包括颅内肿瘤、炎症和血管病变。第六神经麻痹患者应特别注意,因为它是获得性内斜视神经影像学阳性表现的重要因素。
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引用次数: 0
Long-term Efficacy of Genicular Nerve Ablation for Chronic Osteoarthritic Knee Pain: A Prospective Observational Longitudinal Study 膝神经消融治疗慢性骨关节炎膝关节疼痛的长期疗效:一项前瞻性观察性纵向研究
Q3 Medicine Pub Date : 2023-06-01 DOI: 10.33192/smj.v75i6.261692
Thanawut Jitsinthunun, P. Euasobhon, Amornrat Suttijanuwat, Suratsawadee Wangnamthip, P. Rushatamukayanunt, Sukunya Jirachaipitak, N. Zinboonyahgoon, Mohd Suhaimi Tajudin, Rapeepat Narkbunnum, W. Sutipornpalangkul
Objective: When patients with chronic osteoarthritis (OA) knee pain do not respond to conservative treatment and are not suitable for knee arthroplasty, radiofrequency ablation (RFA) of the genicular nerve is probably an alternative treatment. This study aimed to evaluate the efficacy and safety of genicular nerve ablation in severe osteoarthritic knee pain patients.Materials and Methods: Patients with severe chronic OA knee pain were recruited and performed a genicular nerve block (GNB). The patients’ demographic data, numerical rating scale (NRS) at rest and on movement, Thai Oxford knee score (Thai OKS), Thai knee injury and osteoarthritis outcome score physical function short form (Thai KOOS-PS), timed up and go test, brief pain inventory, fall evaluation, and EuroQol 5D-5L were recorded. For the positive block patients (≥50% pain relief for 24 hours), genicular nerve RFA was performed under fluoroscopic or ultrasound guidance. All patients were followed up at the 1st, 3rd, 6th, 9th and 12th months.Results: 21 patients were included in the study, but only 17 were completely followed up for 12 months. At the 12th month, genicular nerve RFA reduced the mean NRS on movement from 7.9±1.6 to 4.0±2.6 (p=0.005), improved knee function (Thai OKS from 18.8±5.3 to 28.5±10.1; p=0.006), but did not significantly improve quality of life (EuroQol-5D-5L from 0.43±0.20 to 0.69±0.33; p=0.130). No adverse events were observed.Conclusion: Genicular nerve radiofrequency ablation in severe chronic OA knee patients demonstrated significant pain relief and functional improvement for up to 12 months without serious adverse events.
目的:当慢性骨关节炎(OA)膝关节疼痛患者对保守治疗无效且不适合进行膝关节置换术时,膝神经射频消融(RFA)可能是一种替代治疗方法。本研究旨在评估膝神经消融治疗严重骨关节炎性膝关节疼痛患者的疗效和安全性。材料和方法:招募患有严重慢性OA膝关节疼痛的患者,并进行膝神经阻滞(GNB)。记录患者的人口统计学数据、休息和运动时的数字评定量表(NRS)、泰式Oxford膝关节评分(泰式OKS)、泰式膝关节损伤和骨关节炎结果评分——身体功能简表(泰式KOOS-PS)、定时测试、简表疼痛量表、跌倒评估和EuroQol 5D-5L。对于阳性阻滞患者(疼痛缓解≥50%,持续24小时),在荧光镜或超声引导下进行膝神经RFA。所有患者均在第1、3、6、9和12个月进行了随访。结果:21名患者被纳入研究,但只有17名患者得到了12个月的完全随访。在第12个月,膝神经RFA将运动时的平均NRS从7.9±1.6降低到4.0±2.6(p=0.005),改善了膝关节功能(泰国OKS从18.8±5.3提高到28.5±10.1;p=0.006),但没有显著改善生活质量(EuroQol-5D-5L从0.43±0.20提高到0.69±0.33;p=0.0130)。没有观察到不良事件。结论:生殖器神经射频消融术治疗严重慢性OA膝关节患者,在长达12个月的时间里,疼痛明显减轻,功能改善,没有出现严重的不良事件。
{"title":"Long-term Efficacy of Genicular Nerve Ablation for Chronic Osteoarthritic Knee Pain: A Prospective Observational Longitudinal Study","authors":"Thanawut Jitsinthunun, P. Euasobhon, Amornrat Suttijanuwat, Suratsawadee Wangnamthip, P. Rushatamukayanunt, Sukunya Jirachaipitak, N. Zinboonyahgoon, Mohd Suhaimi Tajudin, Rapeepat Narkbunnum, W. Sutipornpalangkul","doi":"10.33192/smj.v75i6.261692","DOIUrl":"https://doi.org/10.33192/smj.v75i6.261692","url":null,"abstract":"Objective: When patients with chronic osteoarthritis (OA) knee pain do not respond to conservative treatment and are not suitable for knee arthroplasty, radiofrequency ablation (RFA) of the genicular nerve is probably an alternative treatment. This study aimed to evaluate the efficacy and safety of genicular nerve ablation in severe osteoarthritic knee pain patients.\u0000Materials and Methods: Patients with severe chronic OA knee pain were recruited and performed a genicular nerve block (GNB). The patients’ demographic data, numerical rating scale (NRS) at rest and on movement, Thai Oxford knee score (Thai OKS), Thai knee injury and osteoarthritis outcome score physical function short form (Thai KOOS-PS), timed up and go test, brief pain inventory, fall evaluation, and EuroQol 5D-5L were recorded. For the positive block patients (≥50% pain relief for 24 hours), genicular nerve RFA was performed under fluoroscopic or ultrasound guidance. All patients were followed up at the 1st, 3rd, 6th, 9th and 12th months.\u0000Results: 21 patients were included in the study, but only 17 were completely followed up for 12 months. At the 12th month, genicular nerve RFA reduced the mean NRS on movement from 7.9±1.6 to 4.0±2.6 (p=0.005), improved knee function (Thai OKS from 18.8±5.3 to 28.5±10.1; p=0.006), but did not significantly improve quality of life (EuroQol-5D-5L from 0.43±0.20 to 0.69±0.33; p=0.130). No adverse events were observed.\u0000Conclusion: Genicular nerve radiofrequency ablation in severe chronic OA knee patients demonstrated significant pain relief and functional improvement for up to 12 months without serious adverse events.","PeriodicalId":37270,"journal":{"name":"Siriraj Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47421481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence and Type of Human Papillomavirus Infection in Thai Males with Anogenital Warts 泰国男性肛门生殖器疣患者的人乳头瘤病毒感染率和类型
Q3 Medicine Pub Date : 2023-06-01 DOI: 10.33192/smj.v75i6.262215
S. Jiamton, P. Chanyachailert, Nuttagarn Jantanapornchai, Poramin Patthamalai, Jiraporn Jantaravinid, Yanisorn Nanchaipruek, P. Limphoka, Ya-Nin Nokdhes
Objective: Low-risk (LR) human papillomavirus (HPV) infection is a recognized cause of anogenital warts (AGW). LR-HPV 6 and 11 are the HPV types that were reported to be associated with AGW. However, data specific to the HPV types that associate with AGW in Thailand are scarce. Accordingly, this study aimed to determine the prevalence of HPV in patients with AGW, and to investigate for association between HPV types and AGW among Thai males attending the sexually transmitted disease clinic of Siriraj Hospital – Thailand’s largest national tertiary referral center.Materials and Methods: This prospective study was conducted at the Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand during April 2017 to December 2019. Thai males with at least one AGW were included. AGW specimens were obtained, and HPV genotyping was performed at both the genital and perianal areas.Results: A total of 43 Thai male participants (mean age: 37.3±13.8 years; range: 19-72) with AGW were enrolled. The rate of HPV positive detection at the genital area and the perianal area was 86.0% and 72.1%, respectively. The most common HPV types at the genital area were HPV 6, followed by HPV 11. Alternatively, the most common HPV types at the perianal area were HPV 11, followed by HPV 6.Conclusion: The findings of this study suggest LR-HPV types 6 and 11 as the culprit pathogenic causes of AGW among males in Thailand. These findings further support and emphasize the importance of HPV vaccination for prophylaxis against both HPV and AGW.
目的:低风险(LR)人乳头瘤病毒(HPV)感染是公认的肛门生殖器疣(AGW)的病因。LR-HPV 6和11是被报道与AGW相关的HPV类型。然而,在泰国,与AGW相关的HPV类型的具体数据很少。因此,本研究旨在确定AGW患者中HPV的患病率,并调查在泰国最大的国家三级转诊中心Siriraj医院性病诊所就诊的泰国男性中HPV类型与AGW之间的关系。材料和方法:这项前瞻性研究于2017年4月至2019年12月在泰国曼谷玛希隆大学Siriraj医院医学院皮肤科进行。包括至少有一个AGW的泰国男性。获得AGW标本,并在生殖器和肛周区域进行HPV基因分型。结果:共有43名患有AGW的泰国男性参与者(平均年龄:37.3±13.8岁;范围:19-72岁)入选。生殖器和肛周HPV阳性检出率分别为86.0%和72.1%。生殖器部位最常见的HPV类型是HPV 6,其次是HPV 11。另外,肛周最常见的HPV类型是HPV 11,其次是HPV 6。结论:本研究结果表明,LR-HPV 6型和11型是泰国男性AGW的罪魁祸首致病原因。这些发现进一步支持并强调了HPV疫苗接种对预防HPV和AGW的重要性。
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Siriraj Medical Journal
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