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The Impact of Mergers and Acquisitions in Research-Based Pharmaceutical Companies on Productivity 研究型制药企业并购对生产率的影响
Pub Date : 2012-01-09 DOI: 10.2139/ssrn.1981889
Raymond R. Tjandrawinata, Destrina Grace Simanjuntak
This paper analyzes the impact of mergers and acquisitions (M&A) activities in research-based pharmaceutical companies, specifically the impact of R&D expenditure, sales revenue, and R&D intensity on firms’ productivity, on drug approval in pharmaceutical industries following M&A activities. The model was estimated using annual data, gathered from eight large research-based pharmaceutical companies in the world post-M&A, during the period 2003 until 2010. The regression analysis method uses a pooled regression method with generalized least square (GLS) analysis. The result further shows that following M&A activities, firms’ one-year lagged sales revenue (t-1) and R&D intensity to be positive in increasing significantly the firms’ amount of total approval of drugs in research-based pharmaceutical industries, while, surprisingly firms’ one-year lagged R&D expenditure (t-1) have a negative impact in increasing significantly the firms’ amount of total approval of drugs in research-based pharmaceutical industries.
本文分析了研究型制药企业并购活动对并购后制药行业药品审批的影响,特别是研发支出、销售收入和研发强度对企业生产率的影响。该模型是根据2003年至2010年期间从全球并购后的8家大型研究型制药公司收集的年度数据估算出来的。回归分析方法采用广义最小二乘(GLS)分析的混合回归方法。研究结果进一步表明,并购后企业的1年滞后销售收入(t-1)和研发强度对企业在研究型制药行业的药品总批准量显著增加具有正影响,而企业的1年滞后研发支出(t-1)对企业在研究型制药行业的药品总批准量显著增加具有负影响。
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引用次数: 6
When Should Firms Expose Themselves to Risk 什么时候公司应该承担风险
Pub Date : 2011-07-04 DOI: 10.2139/ssrn.1880062
A. Alexandrov
I analyze a firm making a decision of whether to expose itself to risk in an exogenous parameter when the firm can change a choice variable after observing the realization of the exogenous parameter. For example, whether to choose an advertising campaign with a less certain outcome, when the firm can adjust the product's price after seeing the effects of the campaign. I show that in many cases the firm wants to expose itself to risk and I outline general conditions that need to be satisfied for this result. I then analyze the strategic version of this setup with two competing firms, provide a general characterization, and show that in many cases both firms want to expose themselves to risk, as long as the risks are not too positively correlated. For example, many linear demand and constant marginal cost settings (monopoly, differentiated Bertrand, or differentiated Cournot firms selling substitutes) where the exogenous parameter is a demand or a marginal cost shifter results in the monopolist (or both of the competitors if the risks are not too positively correlated) voluntarily exposing themselves to risk.
我分析了当企业在观察到外生参数的实现后可以改变一个选择变量时,企业是否在外生参数下承担风险的决策。例如,是否选择一个结果不太确定的广告活动,当公司看到广告活动的效果后可以调整产品的价格。我表明,在许多情况下,公司希望暴露自己的风险,我概述了需要满足这种结果的一般条件。然后,我分析了两家竞争公司的战略版本,提供了一个一般的特征,并表明,在许多情况下,两家公司都希望自己暴露在风险中,只要风险不是太积极相关。例如,许多线性需求和恒定边际成本设置(垄断、差异化贝特朗或差异化古诺公司销售替代品),其中外生参数是需求或边际成本转移者,导致垄断者(或两个竞争对手,如果风险不是太正相关)自愿将自己暴露于风险中。
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引用次数: 2
A Portfolio Approach to Economic Development 经济发展的投资组合方法
Pub Date : 2010-11-16 DOI: 10.19030/JABR.V26I2.285
T. Vu, Terrance Jalbert, David L. Hammes
In this paper we introduce and empirically demonstrate a new model of economic development that we call Portfolio Economic Development. Our approach borrows from portfolio theory in finance and focuses on the risk-return nature of development projects. The paper examines how the loss of a dominant industry group from an island economy causes significant economic problems and how those problems might be mitigated by developing the economy in a portfolio context. The approach can help planners select optimal mixes of projects for development of any economy experiencing a transitional period.
本文引入并实证论证了一种新的经济发展模式,即组合经济发展模式。我们的方法借鉴了金融领域的投资组合理论,重点关注开发项目的风险回报性质。本文探讨了从一个岛屿经济中失去一个占主导地位的工业集团如何造成重大的经济问题,以及如何通过在投资组合背景下发展经济来减轻这些问题。这种方法可以帮助规划者为任何处于转型期的经济体的发展选择最佳的项目组合。
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引用次数: 0
Financial Integration and International Diversification Benefits: Cross Country Evidence from a Malaysian Perspective 金融一体化与国际多元化利益:来自马来西亚视角的跨国证据
Pub Date : 2010-07-13 DOI: 10.2139/ssrn.1639710
Surianor Kamaralzaman, F. Samad, M. Isa
A vast deal of research presenting evidence on the benefits of international diversification has been published. The empirical studies came to rather diverse conclusions as the authors used different sampling data, analyzed different countries within a different time period. The purpose of this paper is to analyze the degree of financial integration and benefits of portfolio diversification between the Malaysian equity markets and developed and developing equity markets from Malaysian perspective. The research question is; Is Malaysian financial market integrated to developed and developing markets? It inspects the controversial issues of market segmentation and integration in an emerging market setting, namely Malaysia. In the analysis, the developed and developing equity returns are adjusted for exchange rate fluctuations using Ringgit Malaysia based exchange rates. By employing time series analysis, the paper also seeks to investigate which market actually leads the Malaysian stock market. The research is based on secondary data, existing theories and earlier studies regarding international integration of stock market movements. The methodology utilizes standard co integration analysis, vector error correction model and portfolio theory. We also rely on variance decomposition and impulse response functions to gauge the strength of the interactions among the variables. This study contains secondary data for the period of 1999 to 2008.The study comprises monthly closing Morgan Stanley Composite Index (MSCI) indices of twenty developed and developing countries. The findings from the analysis could be useful to fund managers in their essential decision for portfolio management. The findings may also be of interest to policy makers interested in stock market co movement, since internationalization of markets could represent significant capital inflow or outflow and thus influence savings and consumption decisions.
已经发表了大量研究报告,证明了国际多样化的好处。由于作者使用了不同的抽样数据,分析了不同时期的不同国家,因此实证研究得出了相当不同的结论。本文的目的是从马来西亚的角度分析马来西亚股票市场与发达和发展中股票市场之间的金融一体化程度和投资组合多样化的收益。研究的问题是;马来西亚金融市场是否与发达市场和发展中市场融合?它检查市场细分和整合在新兴市场的设置,即马来西亚有争议的问题。在分析中,发达国家和发展中国家的股本回报率采用以马来西亚林吉特为基础的汇率,根据汇率波动进行调整。通过采用时间序列分析,本文还试图调查哪个市场实际上领先马来西亚股票市场。本研究基于二手数据、现有理论和早期关于股票市场运动国际一体化的研究。该方法采用标准协整分析、矢量误差修正模型和投资组合理论。我们还依靠方差分解和脉冲响应函数来衡量变量之间相互作用的强度。本研究包含1999年至2008年期间的二手数据。该研究包括20个发达国家和发展中国家的摩根士丹利综合指数(MSCI)月度收盘指数。分析结果可能对基金经理进行投资组合管理的关键决策有用。研究结果也可能引起对股票市场变动感兴趣的决策者的兴趣,因为市场国际化可能代表大量资本流入或流出,从而影响储蓄和消费决策。
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引用次数: 0
Why There? Decomposing the Choice of Target Industry 为什么?分解目标行业的选择
Pub Date : 2010-02-19 DOI: 10.2139/ssrn.1555924
Lasse B. Lien, Peter G. Klein
How do diversifying firms chose their target industries? We use two population-level samples and new measures of relatedness to decompose the determinants of diversifying entry into internal factors (firm-specific resources and capabilities) and external factors (industry attractiveness). Our approach captures a variety of sources and types of relatedness and includes measures of resource strength as well as resource relevance, giving us a highly general picture of the drivers of diversification.
多元化企业如何选择目标行业?我们使用两个人口水平的样本和新的相关性度量将多元化进入的决定因素分解为内部因素(企业特定的资源和能力)和外部因素(行业吸引力)。我们的方法捕捉了各种来源和类型的相关性,包括资源强度和资源相关性的测量,为我们提供了多样化驱动因素的高度概括的图景。
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引用次数: 1
Market-Driven Management, Market Space and Value Proposition 市场导向管理、市场空间和价值主张
Pub Date : 2009-06-01 DOI: 10.4468/2009.2.04GNECCHI
F. Gnecchi
In over-supplied markets, companies that have developed market-driven management policies have proved to be able to sustain their proposals, to achieve remunerative income flows and to generate financial resources. A market-driven company is aware of the fact that the opportunities embodied by globalisation are not limited to a mere advantage in terms of reduced costs, but generate conditions for a competitive approach to the market. By revisiting the concept of ‘space’, market-driven businesses focus their commitment on understanding the customer’s assessment; they therefore define their own supply so that they can propose performance that is superior to that guaranteed by competitors. In this context, which determines a clear value proposition, companies have realised that by developing market-space management they can not only modify relations with customers, but even foster the development of collaboration agreements with partners (strategic alliances).
在供应过剩的市场上,制定了市场驱动的管理政策的公司已证明能够维持其建议,实现有报酬的收入流并产生财政资源。一个以市场为导向的公司意识到这样一个事实,即全球化所体现的机会并不仅仅局限于降低成本方面的优势,而是为进入市场的竞争方式创造条件。通过重新审视“空间”的概念,市场驱动型企业将其承诺集中在理解客户的评估上;因此,他们定义自己的供应,这样他们就可以提出优于竞争对手所保证的性能。在这种背景下,这决定了一个明确的价值主张,公司已经意识到,通过发展市场空间管理,他们不仅可以改变与客户的关系,甚至可以促进与合作伙伴(战略联盟)的合作协议的发展。
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引用次数: 26
Corporate Strategies during the Global Downturn: Initiating a Forward-Looking Debate 全球经济低迷时期的企业战略:发起一场前瞻性的辩论
Pub Date : 2009-04-04 DOI: 10.2139/ssrn.1373024
K. Meyer
The global financial crisis has created a structural break in the global economy. Businesses thus need to reassess the strategies they have developed to operate in a highly integrated global economy. Initial reactions have often been defensive as companies downsize and call for government support. However, times of crisis are also times of opportunity. In the short-term, opportunities arise for instance in 'value for money' segments. Long term opportunities require managers to develop foresight to use the crisis to position themselves for the next upswing. Business leaders thus need to develop scenarios of the new economy, and envisage their role in it.The current public debate largely focuses on the origins of the crisis, yet it is time look forward to address the question, how can businesses survive the crisis, and position themselves for the recovery whenever it may come? This paper aims to initiate this forward-looking debate. The main focus thus is on generating ideas on how to move forward, rather than to provide definitive answers.
全球金融危机造成了全球经济的结构性断裂。因此,企业需要重新评估它们为在高度一体化的全球经济中运营而制定的战略。当企业缩减规模并要求政府支持时,最初的反应往往是防御性的。然而,危机时刻也是机遇时刻。在短期内,机会出现了,比如“物有所值”的细分市场。长期机会要求管理者具备远见,利用危机为下一轮上涨做好准备。因此,商业领袖需要制定新经济的情景,并设想他们在其中的角色。目前的公众辩论主要集中在危机的起源上,但现在是时候期待解决这个问题了,企业如何在危机中生存下来,并为可能到来的复苏做好准备?本文旨在发起这一前瞻性的辩论。因此,主要的焦点是产生关于如何前进的想法,而不是提供明确的答案。
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引用次数: 1
Cross-Border Mergers and Acquisitions and European Integration 跨国并购与欧洲一体化
Pub Date : 2009-01-01 DOI: 10.1111/j.1468-0327.2009.00218.x
Nicolas Coeurdacier, Roberto A. De Santis, Antonin Aviat
Cross-border mergers and acquisitions activities (MA (2) joining the EU favoured both horizontal and vertical mergers; (3) policy-makers can help attract capital by reducing the corporate tax rates and the degree of product market regulations and by improving the country's financial systems; (4) the service industry has not yet fully benefited from European integration because the level of protection and barriers to entry in the services sector act as a strong deterrent to cross-border M&As in services.
跨境并购活动(MA(2))加入欧盟有利于横向和纵向并购;(3)政策制定者可以通过降低企业税率和产品市场监管程度以及改善国家金融体系来吸引资本;(4)服务业尚未从欧洲一体化中充分受益,因为服务业的保护水平和进入壁垒对服务业的跨境并购起到了强大的威慑作用。
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引用次数: 144
Diversification Strategy in the Pharmaceutical Industry 制药行业的多元化战略
Pub Date : 2008-10-12 DOI: 10.2139/ssrn.1283129
Ruxandra Ciulu
The study focuses on the manner in which diversification strategy is applied to the pharmaceutical industry. The paper deals with diversification business models, such as the blockbuster model and the generic drugs model. Also, an important trend in the pharmaceutical industry is related to mergers and acquisitions, as well as the choice between diversification and focus. By way of conclusion, I offered the situation of the Romanian pharmaceutical industry, which will probably undergo important changes in the years to come.
本研究的重点是多元化战略应用于制药业的方式。本文探讨了医药企业的多元化经营模式,如重磅产品经营模式和仿制药经营模式。此外,制药行业的一个重要趋势与并购以及多元化和专注之间的选择有关。最后,我介绍了罗马尼亚制药业的情况,该行业在今后几年可能会发生重大变化。
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引用次数: 2
How Much is Too Much: Are Merger Premiums Too High? 多少才算太多:并购溢价是否过高?
Pub Date : 2008-03-01 DOI: 10.2139/ssrn.884244
Antonios Antoniou, Philippe Arbour, Huainan Zhao
Is it too much to pay target firm shareholders a 50% premium on top of market price? Or is it too much to pay a 100% premium when pursuing mergers and acquisitions? How much is too much? In this paper, we examine how the extent of merger premiums paid impacts both the long-run and announcement period stock returns of acquiring firms. We find no evidence that acquirers paying high premiums underperform those paying relatively low premiums in three years following mergers, and the result is robust after controlling for a variety of firm and deal characteristics. Short term cumulative abnormal returns are moreover positively correlated to the level of the premium paid by acquirers. Our evidence therefore suggests that high merger premiums paid are unlikely to be responsible for acquirers' long-run post merger underperformance.
在市场价格的基础上,向目标公司股东支付50%的溢价是否过高?或者,在进行并购时支付100%的溢价是否过高?多少才算太多?在本文中,我们研究了并购溢价支付的程度如何影响收购公司的长期和公告期股票收益。我们没有发现任何证据表明,在并购后的三年内,支付高溢价的收购方表现不如支付相对低溢价的收购方,并且在控制了各种公司和交易特征后,结果是稳健的。此外,短期累积异常收益与收购方支付的溢价水平呈正相关。因此,我们的证据表明,高额的并购溢价不太可能是并购后收购方长期表现不佳的原因。
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引用次数: 87
期刊
Diversification Strategy & Policy eJournal
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