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Journal of Integrated OMICS最新文献

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Therapeutic potential of autologous bone marrow mononuclear cells preconditioned with Erythropoietin implantation in laser channels in patients with Cardiac arteria disease 激光通道促红细胞生成素植入预处理的自体骨髓单核细胞对心脏动脉疾病患者的治疗潜力
Q4 Biochemistry, Genetics and Molecular Biology Pub Date : 2019-06-28 DOI: 10.5584/JIOMICS.V9I1.258
A. Lykov, O. Poveshchenko, M. Surovtseva
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引用次数: 2
THE ROLE OF METALLOTHIONEINS IN MAINTENANCE OF ZINC HOMEOSTASIS AND REDOX STATE IN ERYTHROCYTES OF CARDIOLOGIC PATIENTS WITH METABOLIC SYNDROME 金属硫蛋白在代谢综合征心脏病患者红细胞锌稳态和氧化还原状态中的作用
Q4 Biochemistry, Genetics and Molecular Biology Pub Date : 2019-06-28 DOI: 10.5584/JIOMICS.V9I1.260
Y. Harmaza, A. Tamashevski, E. Slobozhanina
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引用次数: 1
THIAMINASE IS PRESENT IN THE BRAIN OF MAMMALS 硫胺酶存在于哺乳动物的大脑中
Q4 Biochemistry, Genetics and Molecular Biology Pub Date : 2019-06-28 DOI: 10.5584/JIOMICS.V9I1.272
S. Petrov
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引用次数: 0
VITABOLONICA. NEW DIRECTION IN THE VITAMINOLOGY VITABOLONICA。维生素学的新方向
Q4 Biochemistry, Genetics and Molecular Biology Pub Date : 2019-06-28 DOI: 10.5584/JIOMICS.V9I1.252
S. Petrov
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引用次数: 1
THIOCHROME ACTIVATES DNA-POLYMERASE I 硫代铬激活dna聚合酶I
Q4 Biochemistry, Genetics and Molecular Biology Pub Date : 2019-06-28 DOI: 10.5584/JIOMICS.V9I1.261
S. Petrov
{"title":"THIOCHROME ACTIVATES DNA-POLYMERASE I","authors":"S. Petrov","doi":"10.5584/JIOMICS.V9I1.261","DOIUrl":"https://doi.org/10.5584/JIOMICS.V9I1.261","url":null,"abstract":"","PeriodicalId":37675,"journal":{"name":"Journal of Integrated OMICS","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41305045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Molecular mechanisms of adaptation to the habitat depth in visual pigments of A. subulata and L. forbesi squids: on the role of the S270F substitution 亚扁鲟和forbesi鱿鱼视觉色素对生境深度适应的分子机制:S270F取代的作用
Q4 Biochemistry, Genetics and Molecular Biology Pub Date : 2019-06-28 DOI: 10.5584/JIOMICS.V9I1.273
M. N. Ryazantsev, Dmitrii M. Nikolaev, D. Osipov, Daniil M. Strashkov, S. Vyazmin, Vasily Akulov, D. V. Kravtcov, O. Chakchir, M. Panov
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引用次数: 2
Long non-coding RNA in regulation of plasticity of vascular smooth muscle cells 长链非编码RNA在血管平滑肌细胞可塑性调控中的作用
Q4 Biochemistry, Genetics and Molecular Biology Pub Date : 2019-03-15 DOI: 10.5584/JIOMICS.V9I1.265
A. Orekhov, V. Myasoedova, Dongwei Zhang, A. Grechko
Phenotypic plasticity of vascular smooth muscle cells (VSMCs) is a functional property that is essential for vascular remodeling in vessel injury healing. During phenotypic switch, quiescent VSMCs loss contractile capacity but acquire ability to proliferate and migrate to the injured site where they differentiate again to the quiescent state. However, in pathological conditions such as endothelial dysfunction or atherosclerosis, phenotypic changes in arterial VSMCs become deregulated leading to elevated VSMC dedifferentiation, proliferation, excessive extracellular matrix deposits, and intimal thickening. VSMC hyperplasia is a complex mechanism that is coordinated by a network of various regulatory factors. Long non-coding (lnc)RNAs represent an important part of this regulatory network. Some of lncRNAs are involved in VSMC differentiation, apoptosis, and maintenance of VSMC quiescence, while other lncRNAs promote VSMC dedifferentiation, proliferation, and motility. In this review, we characterize these RNAs and their function in the context of possible involvement to atherosclerosis. Normal 0 false false false EN-GB X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Calibri",sans-serif; mso-bidi-font-family:"Times New Roman"; mso-ansi-language:EN-GB; mso-fareast-language:EN-GB;}
血管平滑肌细胞(VSMCs)的表型可塑性是一种功能特性,在血管损伤愈合过程中对血管重塑至关重要。在表型转换过程中,静止的VSMCs失去收缩能力,但获得增殖和迁移到损伤部位的能力,并再次分化到静止状态。然而,在内皮功能障碍或动脉粥样硬化等病理条件下,动脉VSMC的表型改变变得不受调节,导致VSMC去分化、增殖、过度的细胞外基质沉积和内膜增厚。VSMC增生是一个复杂的机制,由多种调节因子网络协调。长链非编码rna (lnc)是该调控网络的重要组成部分。一些lncrna参与VSMC的分化、凋亡和维持VSMC的静止,而其他lncrna则促进VSMC的去分化、增殖和运动。在这篇综述中,我们描述了这些rna及其在动脉粥样硬化可能参与的背景下的功能。正常0 false false false EN-GB X-NONE X-NONE /*样式定义*/表。mso-style-name:"Table Normal";mso-tstyle-rowband-size: 0;mso-tstyle-colband-size: 0;mso-style-noshow:是的;mso-style-priority: 99;mso-style-parent:“”;Mso-padding-alt:0cm 5.4pt;mso-para-margin: 0厘米;mso-para-margin-bottom: .0001pt;mso-pagination: widow-orphan;字体大小:10.0分;无衬线字体类型:“Calibri”;mso-bidi-font-family:宋体;mso-ansi-language: en -;mso-fareast-language: en;}
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引用次数: 0
Vol 8, No 3 (2018) 第八卷第三期(2018)
Q4 Biochemistry, Genetics and Molecular Biology Pub Date : 2018-12-30 DOI: 10.5584/jiomics.v8i3.271
J. Capelo
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引用次数: 0
Special Issue: Book of Abstracts LEISHMANIASIS 2018 特刊:《莱希曼尼亚西斯文摘》2018
Q4 Biochemistry, Genetics and Molecular Biology Pub Date : 2018-12-26 DOI: 10.5584/jiomics.v8i3.270
J. Capelo
SPECIAL ISSUE: SELECTED ABSTRACTS OF THE I INTERNATIONAL CAPARICA CONFERENCE ON LEISHMANIASIS (LEISHMANIASIS 2018
特刊:第I届加勒比利什曼病国际会议摘要选集
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引用次数: 0
Recovering Damaged Documents to Improve Information Retrieval Processes 恢复损坏的文档以改进信息检索过程
Q4 Biochemistry, Genetics and Molecular Biology Pub Date : 2018-12-19 DOI: 10.5584/JIOMICS.V8I3.230
Angel L. Garrido, Álvaro Peiró
Although computer forensics is frequently related to the investigation of computer crimes, it can also be used in civil procedures. An example of case of use is information retrieval from damaged documents, where words have undergone alterations, either accidentally or intentionally. In this paper, we present a new tool able to retrieve information from large volumes of documents whose contents have been damaged. We have designed a new approach to recover the original words, composed of two stages: a text cleaning filter, able to remove non relevant information, and a text correction unit, which gather a general purpose spell checker with a N-gram based spell checker built specifically for the domain of the documents. The benefits of using this combined approach are two-fold: on the one hand, the general spell checker allows us to leverage all the general purpose techniques that are usually used to perform the corrections; on the other hand, the use of an N-gram based model allows us to adapt them to the particular domain we are tackling exploiting text regularities detected in successfully processed domain documents. The result of the correction allows us to improve automatic information retrieval tasks of from the texts. We have tested it using a real data set by using an information extraction tool based on semantic technologies in collaboration with the Spanish company InSynergy Consulting.
虽然计算机取证经常与计算机犯罪的调查有关,但它也可以用于民事诉讼。使用的一个例子是从损坏的文档中检索信息,其中单词经历了无意或有意的更改。在本文中,我们提出了一种新的工具,能够从内容已损坏的大量文档中检索信息。我们设计了一种新的方法来恢复原始单词,它由两个阶段组成:一个文本清理过滤器,能够删除不相关的信息;一个文本校正单元,它收集了一个通用的拼写检查器,其中包含一个专门为文档领域构建的基于N-gram的拼写检查器。使用这种组合方法的好处是双重的:一方面,通用拼写检查器允许我们利用所有通常用于执行更正的通用技术;另一方面,使用基于N-gram的模型使我们能够利用在成功处理的领域文档中检测到的文本规律,使它们适应我们正在处理的特定领域。修正的结果使我们能够改进文本信息的自动检索任务。我们与西班牙公司InSynergy Consulting合作,使用基于语义技术的信息提取工具,使用真实数据集对其进行了测试。
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引用次数: 3
期刊
Journal of Integrated OMICS
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