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“Nigerium massiliense” gen. nov., sp. nov., a new bacterium isolated from the gut from a patient with acute malnutrition 一种从急性营养不良患者的肠道中分离出来的新细菌
Q1 Medicine Pub Date : 2016-09-01 DOI: 10.1016/j.humic.2016.08.001
Sory Ibrahima Traore , Souleymane Brah , Jeremy Delerce , Pierre Edouard Fournier , Didier Raoult , Sophie Edouard

We propose the main characteristics of a new bacterium named “Nigerium massiliense” strain SIT5 (CSURP1302) that was isolated from the stool of a 2-year-old Nigerian child suffering from kwashiorkor, a form of severe acute malnutrition.

我们提出了一种名为“尼日利亚马氏菌”菌株SIT5 (CSURP1302)的新细菌的主要特征,该菌株是从一名患有严重急性营养不良的2岁尼日利亚儿童的粪便中分离出来的。
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引用次数: 0
Diet influence on the gut microbiota and dysbiosis related to nutritional disorders 饮食对肠道菌群和与营养失调相关的生态失调的影响
Q1 Medicine Pub Date : 2016-09-01 DOI: 10.1016/j.humic.2016.09.001
Maryam Tidjani Alou , Jean-Christophe Lagier , Didier Raoult

Studies concerning the gut microbiota have exponentially increased since the 1970s. A healthy gut microbiota is essential for growth and weight gain in infants as well as for a thorough harvest of energy from diet through a role in digestion. Study techniques include culture-independent and culture-dependent methods aiming at describing the gut microbiota taxonomically and functionally. Healthy gut microbiota plays a role in digestion by metabolizing indigestible macronutrients resulting in short chain fatty acids and other bioactive compounds. Diet was proven to influence the composition of the gut microbiota with specific changes to the major macronutrient contained in the diet. Since diet has an influence on gut microbiota’s composition, nutritional disorders such as obesity, severe acute malnutrition and anorexia nervosa are linked to an alteration of the gut microbiota mirroring the physiopathology of the nutritional disorder. These alterations should be the target of future therapeutic interventions in nutritional disorders.

自20世纪70年代以来,有关肠道微生物群的研究呈指数增长。健康的肠道菌群对婴儿的生长和体重增加至关重要,也对通过消化从饮食中获取能量至关重要。研究技术包括培养独立和培养依赖的方法,旨在描述肠道微生物群的分类和功能。健康的肠道微生物群通过代谢产生短链脂肪酸和其他生物活性化合物的不可消化的大量营养素,在消化中发挥作用。饮食已被证明会影响肠道微生物群的组成,具体改变饮食中所含的主要宏量营养素。由于饮食对肠道微生物群的组成有影响,营养失调,如肥胖、严重急性营养不良和神经性厌食症,与肠道微生物群的改变有关,反映了营养失调的生理病理。这些改变应该成为未来营养失调治疗干预的目标。
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引用次数: 121
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Human Microbiome Journal
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