Pub Date : 2019-05-01DOI: 10.1093/MED/9780198786757.003.0014
M. Powell, A. Taylor
Chapter 14 discusses carcinoma of the uterus (the endometrium and cervix), including discussion on anatomy, cervical cancer, uterine cancer, pelvic and para-aortic nodal irradiation, palliative treatment, and management of patients undergoing pelvic radiotherapy.
{"title":"Uterus: Endometrium and Cervix","authors":"M. Powell, A. Taylor","doi":"10.1093/MED/9780198786757.003.0014","DOIUrl":"https://doi.org/10.1093/MED/9780198786757.003.0014","url":null,"abstract":"Chapter 14 discusses carcinoma of the uterus (the endometrium and cervix), including discussion on anatomy, cervical cancer, uterine cancer, pelvic and para-aortic nodal irradiation, palliative treatment, and management of patients undergoing pelvic radiotherapy.","PeriodicalId":380029,"journal":{"name":"External Beam Therapy","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123404254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-01DOI: 10.1093/MED/9780198786757.003.0009
R. Glynne-Jones, M. Harrison
Chapter 9 discusses squamous cell carcinoma of the anus and includes discussion on specific Phase III trials that establish chemoradiotherapy as the treatment of choice, radiotherapy dose, brachytherapy, radical primary treatment, postoperative adjuvant treatment, supportive care during radiotherapy, palliative treatment, therapeutic assessment and follow-up, and current and future research.
{"title":"Squamous cell carcinoma of the anus","authors":"R. Glynne-Jones, M. Harrison","doi":"10.1093/MED/9780198786757.003.0009","DOIUrl":"https://doi.org/10.1093/MED/9780198786757.003.0009","url":null,"abstract":"Chapter 9 discusses squamous cell carcinoma of the anus and includes discussion on specific Phase III trials that establish chemoradiotherapy as the treatment of choice, radiotherapy dose, brachytherapy, radical primary treatment, postoperative adjuvant treatment, supportive care during radiotherapy, palliative treatment, therapeutic assessment and follow-up, and current and future research.","PeriodicalId":380029,"journal":{"name":"External Beam Therapy","volume":"12 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"113984428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-01DOI: 10.1093/MED/9780198786757.003.0006
K. Franks, F. McDonald, G. Hanna
Chapter 6 discusses radiotherapy for thoracic tumours and includes discussion on lung cancer. The chapter covers assessment of patients with lung cancer for radical radiotherapy, patient positioning for radical radiotherapy for lung cancer, tumour motion, target delineation, organs at risk, implementation on the treatment machine, treatment verification , radical treatment of non-small cell lung cancer, radical treatment for small cell lung cancer, and palliative thoracic treatment for lung cancer. It also covers mesothelioma (including current indications for radiotherapy, patient positioning, target delineation, planning, and dose prescription) and thymic tumours (including current indications for radiotherapy, radical treatment, and palliative radiotherapy).
{"title":"Radiotherapy for thoracic tumours","authors":"K. Franks, F. McDonald, G. Hanna","doi":"10.1093/MED/9780198786757.003.0006","DOIUrl":"https://doi.org/10.1093/MED/9780198786757.003.0006","url":null,"abstract":"Chapter 6 discusses radiotherapy for thoracic tumours and includes discussion on lung cancer. The chapter covers assessment of patients with lung cancer for radical radiotherapy, patient positioning for radical radiotherapy for lung cancer, tumour motion, target delineation, organs at risk, implementation on the treatment machine, treatment verification , radical treatment of non-small cell lung cancer, radical treatment for small cell lung cancer, and palliative thoracic treatment for lung cancer. It also covers mesothelioma (including current indications for radiotherapy, patient positioning, target delineation, planning, and dose prescription) and thymic tumours (including current indications for radiotherapy, radical treatment, and palliative radiotherapy).","PeriodicalId":380029,"journal":{"name":"External Beam Therapy","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115014968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-01DOI: 10.1093/med/9780198786757.003.0012
P. Hoskin
Chapter 12 discusses the role of radiotherapy in testicular cancer and how it is becoming less prominent. The mainstay of treatment is radical orchidectomy and, where there is a risk of metastatic disease, combination chemotherapy. Radiotherapy may be indicated in the following situations: 1) stage I and IIa testicular seminoma delivering prophylactic para-aortic lymph nodes irradiation, and 2) palliative treatment in the management of chemotherapy resistant disease.
{"title":"Testis","authors":"P. Hoskin","doi":"10.1093/med/9780198786757.003.0012","DOIUrl":"https://doi.org/10.1093/med/9780198786757.003.0012","url":null,"abstract":"Chapter 12 discusses the role of radiotherapy in testicular cancer and how it is becoming less prominent. The mainstay of treatment is radical orchidectomy and, where there is a risk of metastatic disease, combination chemotherapy. Radiotherapy may be indicated in the following situations: 1) stage I and IIa testicular seminoma delivering prophylactic para-aortic lymph nodes irradiation, and 2) palliative treatment in the management of chemotherapy resistant disease.","PeriodicalId":380029,"journal":{"name":"External Beam Therapy","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116287502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-01DOI: 10.1093/med/9780198786757.003.0005
C. Coles, M. Brunt, A. Kirby, S. Lightowlers, N. Twyman
Chapter 5 discusses breast radiotherapy and includes discussion on the evidence-based rationale for radiotherapy, including adjuvant loco-regional radiotherapy and other indications, adverse effects of breast and lymphatic radiotherapy, pre-planning procedures, radiotherapy planning, treatment and verification, and patient assessment and follow-up.
{"title":"Breast radiotherapy","authors":"C. Coles, M. Brunt, A. Kirby, S. Lightowlers, N. Twyman","doi":"10.1093/med/9780198786757.003.0005","DOIUrl":"https://doi.org/10.1093/med/9780198786757.003.0005","url":null,"abstract":"Chapter 5 discusses breast radiotherapy and includes discussion on the evidence-based rationale for radiotherapy, including adjuvant loco-regional radiotherapy and other indications, adverse effects of breast and lymphatic radiotherapy, pre-planning procedures, radiotherapy planning, treatment and verification, and patient assessment and follow-up.","PeriodicalId":380029,"journal":{"name":"External Beam Therapy","volume":"136 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123256235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-01DOI: 10.1093/MED/9780198786757.003.0023
P. Díez, E. Aird
Chapter 23 discusses quality assurance of the patient pathway, concentrating on quality control of treatment planning and delivery. There is also discussion on relevant legislation associated with the radiotherapy process as well as a section on quality assurance for clinical trials.
{"title":"Quality assurance in radiotherapy","authors":"P. Díez, E. Aird","doi":"10.1093/MED/9780198786757.003.0023","DOIUrl":"https://doi.org/10.1093/MED/9780198786757.003.0023","url":null,"abstract":"Chapter 23 discusses quality assurance of the patient pathway, concentrating on quality control of treatment planning and delivery. There is also discussion on relevant legislation associated with the radiotherapy process as well as a section on quality assurance for clinical trials.","PeriodicalId":380029,"journal":{"name":"External Beam Therapy","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126595055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-01DOI: 10.1093/MED/9780198786757.003.0021
H. Mandeville
Chapter 21 discusses principles of paediatric radiation oncology including discussion on proton therapy for paediatric tumours, intensity-modulated radiotherapy, radiotherapy quality assurance, toxicity of radiotherapy for children, chemotherapy and radiotherapy interactions, leukaemia, Hodgkin lymphoma, non-Hodgkin lymphoma, neuroblastoma, Wilms’ tumour, rhabdomyosarcoma, Ewing’s sarcoma, osteosarcoma, central nervous system tumours, and high-grade glioma.
Pub Date : 2019-05-01DOI: 10.1093/MED/9780198786757.003.0020
J. Wylie
Chapter 20 covers sarcomas of soft tissue and bone and includes discussion of radiotherapy for soft tissue sarcomas (including indications for radiotherapy, essential investigations for planning radiotherapy, patient preparation, planning imaging required for target definition, target definition, dose fractionation, and critical organs and tolerance doses,including the sites forearm, hands and feet, retroperitoneum, chest wall, and spinal/para-spinal), particular histologies (angiosarcoma and fibromatosis), particular radiotherapy techniques, and palliative treatment (including cerebral and lung secondaries),
{"title":"Sarcomas of soft tissue and bone","authors":"J. Wylie","doi":"10.1093/MED/9780198786757.003.0020","DOIUrl":"https://doi.org/10.1093/MED/9780198786757.003.0020","url":null,"abstract":"Chapter 20 covers sarcomas of soft tissue and bone and includes discussion of radiotherapy for soft tissue sarcomas (including indications for radiotherapy, essential investigations for planning radiotherapy, patient preparation, planning imaging required for target definition, target definition, dose fractionation, and critical organs and tolerance doses,including the sites forearm, hands and feet, retroperitoneum, chest wall, and spinal/para-spinal), particular histologies (angiosarcoma and fibromatosis), particular radiotherapy techniques, and palliative treatment (including cerebral and lung secondaries),","PeriodicalId":380029,"journal":{"name":"External Beam Therapy","volume":"01 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127191562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-01DOI: 10.1093/MED/9780198786757.003.0003
Y. Tsang
Chapter 3 discusses how successful delivery of external beam radiotherapy such as intensity-modulated radiotherapy and image-guided radiotherapy involves a number of complex processes beginning with the decision by the clinical oncologist to use radiotherapy as part of the patient’s cancer management, through the preparation and planning of the patient’s treatment, to the verification of the patient position and radiation dose delivered at the time of treatment.
{"title":"Treatment delivery, intensity-modulated radiotherapy, and image-guided radiotherapy","authors":"Y. Tsang","doi":"10.1093/MED/9780198786757.003.0003","DOIUrl":"https://doi.org/10.1093/MED/9780198786757.003.0003","url":null,"abstract":"Chapter 3 discusses how successful delivery of external beam radiotherapy such as intensity-modulated radiotherapy and image-guided radiotherapy involves a number of complex processes beginning with the decision by the clinical oncologist to use radiotherapy as part of the patient’s cancer management, through the preparation and planning of the patient’s treatment, to the verification of the patient position and radiation dose delivered at the time of treatment.","PeriodicalId":380029,"journal":{"name":"External Beam Therapy","volume":"134 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133657188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-01DOI: 10.1093/med/9780198786757.003.0011
N. James, D. Fackrell, A. Zarkar
Chapter 11 discusses the considerable controversy about the optimal management of localized, muscle invasive bladder cancer. Surgical removal of the bladder is considered the ‘gold standard’ in many countries but there is no randomized trial to underpin this statement, and many patients are unfit for surgery. Reported 5-year survival rates with radiotherapy are similar to surgical series and there are many patients for whom radical surgery is simply not suitable and hence bladder-preserving techniques are appropriate.
{"title":"Bladder cancer","authors":"N. James, D. Fackrell, A. Zarkar","doi":"10.1093/med/9780198786757.003.0011","DOIUrl":"https://doi.org/10.1093/med/9780198786757.003.0011","url":null,"abstract":"Chapter 11 discusses the considerable controversy about the optimal management of localized, muscle invasive bladder cancer. Surgical removal of the bladder is considered the ‘gold standard’ in many countries but there is no randomized trial to underpin this statement, and many patients are unfit for surgery. Reported 5-year survival rates with radiotherapy are similar to surgical series and there are many patients for whom radical surgery is simply not suitable and hence bladder-preserving techniques are appropriate.","PeriodicalId":380029,"journal":{"name":"External Beam Therapy","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127456189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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