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COVID-related mucormycosis mimicking dental infection 与新冠肺炎相关的毛霉菌病,模仿牙齿感染。
Q3 Dentistry Pub Date : 2023-06-01 DOI: 10.1016/j.omsc.2023.100310
Saja A. Alramadhan , Sumita S. Sam , Shaun Young , Donald M. Cohen , Mohammed N. Islam , Indraneel Bhattacharyya

Background

A recent increase in the prevalence of mucormycosis of the head and neck in patients who have recovered from COVID-19 following hospitalization has been reported. A Majority of the cases have been reported from India. Conditions such as diabetes mellitus, use of corticosteroids for other autoimmune conditions, organ transplant, immunosuppression, immunodeficiency, and malignancies especially hematologic ones, are all known risk factors for mucormycosis. Recently, hospitalization for COVID-19 has been added to the list of risk factors for opportunistic mucormycosis infection. This is likely attributable to the high doses and prolonged use of corticosteroids in the treatment of hospitalized COVID-19 patients. Case Description: Two patients with post-COVID-19 associated rhinocerebral mucormycosis presented with profound unexplained dental disease including tooth mobility and dental abscess mimicking periodontal disease. The patients were previously hospitalized for COVID-19 and received prolonged treatment with high doses of corticosteroids. The patients responded well to the surgical debridement with or without antifungal therapy. Conclusion: Oral healthcare providers including oral and maxillofacial surgeons, dentists, dental hygienists, and other dental practitioners can play a vital role in the recognition and early diagnosis of rhinocerebral mucormycosis given the large number of patients with severe COVID-19 infection who have recovered following hospitalization and/or received long-term high doses of immunosuppressive treatment.

据报道,在新冠肺炎住院后康复的患者中,头部和颈部毛霉菌病的发病率最近有所上升。大多数病例来自印度。糖尿病、皮质类固醇用于其他自身免疫性疾病、器官移植、免疫抑制、免疫缺陷和恶性肿瘤,尤其是血液病,都是毛霉菌病的已知风险因素。最近,新冠肺炎住院已被列入机会性毛霉菌病感染的危险因素列表。这可能是由于在治疗住院新冠肺炎患者时使用了高剂量和长时间的皮质类固醇。病例描述:两名COVID-19后相关的鼻脑毛霉菌病患者出现了严重的不明原因的牙科疾病,包括牙齿松动和类似牙周病的牙脓肿。这些患者此前因新冠肺炎住院,并接受了高剂量皮质类固醇的长期治疗。患者对有或无抗真菌治疗的外科清创术反应良好。结论:口腔保健提供者包括口腔颌面外科医生、牙医、牙科保健师、,鉴于大量严重新冠肺炎感染患者在住院治疗后康复和/或接受长期高剂量免疫抑制治疗,其他牙科医生可以在鼻脑毛霉菌病的识别和早期诊断中发挥重要作用。
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引用次数: 0
A rare case of bilateral multifocal nodular oncocytic hyperplasia of the parotid gland 一例罕见的双侧腮腺多灶结节性嗜酸细胞增生
Q3 Dentistry Pub Date : 2023-06-01 DOI: 10.1016/j.omsc.2023.100312
Wauters Lauri , Geers Caroline , Büttner Michael

Multifocal nodular oncocytic hyperplasia (MNOH) is an extremely rare pathological entity occurring in the parotid gland, even more rarely described in the submandibular gland. We report a case of bilateral parotid MNOH in a 71-year-old woman and perform a search of the existing literature that is compiled in a table. Fifty-nine cases are described in 34 publications. Half of the published cases presented as bilateral lesions, either synchronous or metachronous. Other lesions of the oncocyte-spectrum such as oncocytomas are frequently described on the ground of oncocytic hyperplasia. MNOH rarely occurs before the age of 40 years and mean age of the described cases is 62 years. The condition is considered as benign by all authors, but surgery was performed in nearly all cases, most often due to a lack of diagnostic certainty. Nevertheless, the radiologic presentation of MNOH is often highly suggestive. Based on the existing literature, recommendations for the management of MNOH are formulated.

多灶性结节性嗜瘤细胞增生(MNOH)是一种极其罕见的病理实体,发生在腮腺,甚至更罕见的描述在下颌腺。我们报告一个病例的双侧腮腺MNOH在一个71岁的妇女,并执行搜索现有的文献汇编在一个表。在34份出版物中描述了59个病例。一半已发表的病例表现为双侧病变,同步或异时。癌细胞谱上的其他病变,如癌细胞瘤,常以癌细胞增生为基础来描述。MNOH很少发生在40岁之前,所述病例的平均年龄为62岁。所有作者都认为这种情况是良性的,但几乎所有病例都进行了手术,最常见的原因是缺乏诊断的确定性。然而,MNOH的放射学表现通常是高度提示的。在现有文献的基础上,对MNOH的管理提出建议。
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引用次数: 0
A hard nodule of the upper lip 上唇硬结
Q3 Dentistry Pub Date : 2023-06-01 DOI: 10.1016/j.omsc.2023.100315
Dries Govaerts , Esther Hauben , Constantinus Politis

In this case report, we present a pleomorphic adenoma that presented as a hard nodule on the upper lip in a man in his 30s. Differential diagnosis is necessary, as there are multiple causes of a nodule in the lip. The nodule was excised extracapsularly and a histopathological examination was performed. Although the tumor was found to be benign, there is a risk of late malignant conversion, which underscores the importance of prompt treatment.

在这个病例报告中,我们报告了一个30多岁的男性上唇的多形性腺瘤,表现为坚硬的结节。鉴别诊断是必要的,因为有多种原因的结节在唇。在囊外切除结节并进行组织病理学检查。虽然肿瘤被发现是良性的,但有晚期恶性转化的风险,这强调了及时治疗的重要性。
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引用次数: 0
Reconstruction of frontal bone using patient specific implant poly-ether-ketone-ketone via a lateral nasal/lynch incision 采用患者特异性种植体聚醚酮酮经鼻/鼻侧切口重建额骨
Q3 Dentistry Pub Date : 2023-06-01 DOI: 10.1016/j.omsc.2023.100293
Dana Jackson, Temidayo Obayomi, Francis Mir

Trauma to the craniofacial structures can result in both functional and aesthetic defects. Mucosa lines the frontal sinus outflow tract (FSOT) from the frontal sinus to the nasal cavity and any obstruction to the flow of mucus can lead to complications such as mucocele formation or chronic frontal sinusitis. If the FSOT or posterior cranial vault is not damaged, reestablishment of the aesthetic contour of the frontal bandeau becomes the primary concern. There are several materials that have been proposed for treatment of frontal bone defects. Technological advances such as computed tomography (CT) scan, computer assisted design (CAD), and computer assisted manufacturing (CAM), have led to the development of three-dimensionally printed patient-specific implants. Poly-Ether-Ketone-Ketone (PEKK) is a biocompatible material from the same polyaromatic semicrystalline polymer family as Poly-Ether-Ether-Ketone (PEEK). Patient specific implants have given way to smaller surgical incisions that enable the implant to be slipped into the bony defect to reestablish contour of the frontal bandeau and secured with lag screws. The aim of this study is to describe a case of frontal bone defect reconstruction with PEKK implant via a lateral nasal/Lynch incision.

颅面结构的创伤可导致功能和美学缺陷。从额窦到鼻腔的额窦流出道(FSOT)由粘膜构成,任何阻碍粘液流动的因素都可能导致并发症,如粘液囊肿形成或慢性额窦炎。如果FSOT或后颅穹窿未受损,则重建额带的美观轮廓成为首要考虑的问题。有几种材料已被提出用于治疗额骨缺损。诸如计算机断层扫描(CT)、计算机辅助设计(CAD)和计算机辅助制造(CAM)等技术的进步导致了三维打印患者特异性植入物的发展。聚醚酮酮(PEKK)是一种生物相容性材料,与聚醚醚酮(PEEK)属于同一聚芳族半结晶聚合物家族。患者特定的植入物已经让位于较小的手术切口,使植入物能够滑入骨缺损以重建额叶带的轮廓,并用拉力螺钉固定。本研究的目的是描述一个用PEKK种植体经侧鼻/Lynch切口重建额骨缺损的病例。
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引用次数: 0
Romosozumab-associated medication-related osteonecrosis of the jaw 罗莫索珠单抗相关药物治疗的颌骨坏死
Q3 Dentistry Pub Date : 2023-06-01 DOI: 10.1016/j.omsc.2023.100318
Benjamin Palla , John Anderson , Michael Miloro , Sarah Moles , Nicholas Callahan

This is the first reported case of medication-related osteonecrosis of the jaw (MRONJ) resulting from the use of romosozumab, a new anti-resorptive medication that functions through inhibition of sclerostin. It was approved by the FDA in 2019, and mentioned in the 2022 AAOMS Position Paper on MRONJ. Although initial evidence from animal studies and clinical trials showed a low risk of MRONJ from romosozumab, recent publications on adverse event monitoring demonstrate the need for continued observation and research. Little is known regarding the risk of MRONJ from romosozumab, however, oral surgeons will inevitably be first line clinicians to manage patients on this medication. The purpose of this extremely unusual case report is to improve knowledge and heighten awareness about the association between romosozumab and MRONJ.

这是首次报道的由使用romosozumab引起的药物相关性颌骨骨坏死(MRONJ)病例,romosozumab是一种通过抑制硬化蛋白起作用的新型抗吸收药物。它于2019年获得FDA批准,并在2022年AAOMS关于MRONJ的立场文件中提到。尽管来自动物研究和临床试验的初步证据显示,romosozumab产生MRONJ的风险较低,但最近发表的不良事件监测报告表明,需要继续进行观察和研究。关于romosozumab的MRONJ风险知之甚少,然而,口腔外科医生将不可避免地成为第一线临床医生来管理使用这种药物的患者。这一极不寻常的病例报告的目的是提高对romosozumab和MRONJ之间关联的认识和认识。
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引用次数: 1
Total temporomandibular mandibular joint alloplastic replacement as first line treatment for condylar fracture 颞下颌关节置换术治疗髁突骨折
Q3 Dentistry Pub Date : 2023-06-01 DOI: 10.1016/j.omsc.2023.100302
Fabio G. Ritto , John R. Zuniga

The treatment of condylar fractures has been the subject of debate and controversy. Open reduction and internal fixation, along with closed reduction, are the 2 main treatment modalities when well indicated and performed. In specific situations, however, the success of both treatment modalities can be challenged by local or systemic conditions. Alloplastic total temporomandibular joint replacement (TMJR) with the current systems, Biomet and Stryker, has proven to be successful in the long-term. The authors present 2 cases and propose the consideration of TMJR as a first-line treatment for condylar fractures in the following situations: fractures older than 4 weeks; 2) elderly patients with severely dislocated or displaced condyles; 3) condylar dislocation into the cranial fossa; 4) maxillomandibular fixation is not a viable option.

髁突骨折的治疗一直是争论和争议的主题。切开复位和内固定以及闭合复位是两种主要的治疗方式,如果指征和执行得当。然而,在特定情况下,两种治疗方式的成功可能会受到局部或全身条件的挑战。同种异体全颞下颌关节置换术(TMJR)采用目前的系统,Biomet和Stryker,已被证明是长期成功的。作者报告了2例病例,并建议在以下情况下考虑将TMJR作为髁突骨折的一线治疗方法:骨折大于4周;2)老年患者髁突严重脱位或移位;3)髁突脱位入颅窝;上颌下颌固定不是一个可行的选择。
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引用次数: 0
Penetrating orbital trauma by a large metallic foreign body: A case report 大型金属异物穿透眼眶外伤1例
Q3 Dentistry Pub Date : 2023-06-01 DOI: 10.1016/j.omsc.2023.100307
Mohamed Elseyoufi , Hassan Abdel-Ghany

Intraorbital foreign bodies are not uncommon, and the outcome is not always satisfying after management. A 41-year-old male presented to the ER with a history of occupational trauma 30 minutes before presentation. On non-contrast CT, a 4 cm curved nail was visualized near the lateral orbital wall penetrating the zygomatic buttress with no evidence of retrobulbar haemorrhage or bulbus oculi perforation. Under coverage of proper antibiotics, the nail was removed using lateral eyebrow approach keeping the globe intact, and the wound was closed in layers. The injured eye demonstrated free range of movement postoperatively. The patient was then referred for retinal repair surgery. Early management and meticulous extraction can lead to satisfying outcomes even with large foreign bodies.

眶内异物并不少见,治疗后的结果并不总是令人满意。一名41岁男性在就诊前30分钟有职业创伤史。在非对比CT上,在眶外壁附近可见一枚4厘米弯曲的钉子,穿过颧支撑,未见球后出血或球眼穿孔。在适当的抗生素覆盖下,采用外侧眉入路去除指甲,保持眼球完整,伤口分层闭合。伤眼术后活动范围自由。患者随后接受视网膜修复手术。即使是较大的异物,早期处理和细致的拔除也能取得令人满意的结果。
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引用次数: 0
Anterolateral thigh harvesting for head and neck reconstruction without Doppler: Risky or not? 不经多普勒切除前外侧大腿进行头颈部重建术:是否有风险?
Q3 Dentistry Pub Date : 2023-06-01 DOI: 10.1016/j.omsc.2023.100304
Georgia-Alexandra Spyropoulou , Konstantinos Vahtsevanos , Konstantinos Antoniades , Eleni Karagergou , Sofia Papadopoulou , Efterpi Demiri

Background

Anterolateral thigh flap (ALT) is used as a workhorse flap for head and neck reconstruction. The most used method to map the perforators nowadays is hand-held Doppler although several more sophisticated techniques have been described. This paper is to investigate whether harvesting the ALT flap without preoperative mapping is safe.

Materials and methods

Twenty consecutive patients were randomly assigned to one of two groups: A or B. Patients of A group (n = 10) were marked before the operation with the use of a Doppler probe whilst patients of group B (n = 10) were not marked preoperatively using Doppler to detect the perforators. Complications and time of ALT dissection were documented.

Results

There was no statistical difference of complications between the two groups. Mean time of flap harvesting (skin incision up to main pedicle) was approximately 140 min in group A and 165 min in group B (statistically significantly less in group A p = 0.008).

Conclusions

This paper is an indication that harvesting the ALT flap without preoperative mapping, even with hand-held Doppler, does not compromise safety of the procedure although operative time is prolonged.

背景:大腿外侧皮瓣(ALT)是头颈部重建的主要皮瓣。目前最常用的射孔定位方法是手持式多普勒,尽管也有一些更复杂的技术。本文的目的是探讨在术前不做定位的情况下摘取ALT皮瓣是否安全。材料与方法将20例患者随机分为A组和B组,A组(n = 10)术前采用多普勒穿刺标记,B组(n = 10)术前不采用多普勒穿刺标记。记录ALT剥离的并发症及时间。结果两组患者并发症发生率无统计学差异。A组皮瓣收获(皮肤切口至主蒂)的平均时间约为140 min, B组约为165 min (A组差异有统计学意义p = 0.008)。结论在术前不做定位的情况下获取ALT皮瓣,即使使用手持多普勒,虽然延长了手术时间,但并不影响手术的安全性。
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引用次数: 0
The 360-degree continuous mattress suture in dental implant surgery: A case series 种植牙手术中360度连续床垫缝合:一个病例系列
Q3 Dentistry Pub Date : 2023-06-01 DOI: 10.1016/j.omsc.2023.100311
Ernesto Bruschi , Stefano Granata , Massimiliano Agrestini

The necessity of an ‘adequate’ keratinized mucosa at the emergence profile of dental implants is a controversial and debated topic. But, in recent years, research suggests that a minimum of at least 2mm of keratinized mucosa is recommended for the maintenance of peri-implant health. The latest systematic reviews on this topic are largely in favor of keratinized mucosa, as are the recommendations of some expert panels. The present paper presents a novel technique for peri-implant flap suturing that can be used in combination with soft tissue augmentation procedures, such as laterally positioned flaps, roll-flaps, and decellularized dermal matrix xenografts. The technique stabilizes the flap on the buccal surface of the healing screw or the emergence profile of the tissue-level implant with a circumferential continuous mattress design that is anchored on the buccal margins and/or periosteum with a final knot. The technique is carried out with a sterile 6/0 synthetic absorbable glyconate monofilament surgical suture (Monosyn, Bbraun, B. Braun Milano S. p.A., Via Vincenzo da Seregno, 14, 20,161 Milan, Italy). This type of suture is ideal, as it slides smoothly through the tissues and allows for the ideal adjustment of the tension and the position of the flap margins until the final knot is positioned. Furthermore, these augmentative procedures make use of second-intention healing and mattress sutures are always ideal to stabilize flap margins without excess tension in such cases. This case series involves patients with a reduced band of keratinized mucosa and, as such, in need of augmentative flap procedures.

在牙种植体出现时,“足够的”角化粘膜的必要性是一个有争议和争论的话题。但是,近年来的研究表明,推荐至少2毫米的角质化粘膜来维持种植体周围的健康。关于这一主题的最新系统综述在很大程度上支持角化粘膜,一些专家小组的建议也是如此。本文介绍了一种种植体周围皮瓣缝合的新技术,该技术可与软组织增强手术结合使用,如侧向定位皮瓣,滚动皮瓣和脱细胞真皮基质异种移植物。该技术稳定愈合螺钉颊表面的皮瓣或组织级植入物的涌现轮廓,采用环状连续床垫设计,以最终结固定在颊缘和/或骨膜上。该技术使用无菌6/0合成可吸收糖酸盐单丝手术缝线(Monosyn, Bbraun, B. Braun Milano s.p.a., Via Vincenzo da Seregno, 14,20,161米兰,意大利)。这种类型的缝线是理想的,因为它平滑地穿过组织,并允许理想的张力调整和皮瓣边缘的位置,直到最终的结定位。此外,这些增强手术利用二次愈合和床垫缝合线总是理想的稳定皮瓣边缘,在这种情况下没有过度的张力。本病例系列涉及角化粘膜带减少的患者,因此,需要增加皮瓣手术。
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引用次数: 0
An unusual case of pilomatrix carcinoma of the salivary glands in a young man 一例罕见的青年人唾液腺毛基质癌
Q3 Dentistry Pub Date : 2023-06-01 DOI: 10.1016/j.omsc.2023.100320
Umberto Committeri , Giovanna Norino , Antonio Arena , Vincenzo Abbate , Giovanni Salzano , Simona Barone , Francesco Giovacchini , Luigi Califano , Giovanni Dell’Aversana Orabona

We describe here a rare case of pilomatrix carcinoma in the right parotid region, arising in a young patient.

Pilomatrix carcinoma is a rare, locally aggressive tumor with a tendency to recur. Pilomatrixoma is a superficial benign skin tumor arising from the matrix cells of the hair follicle generally located in the scalp, face, and upper limbs. Clinically, it usually presents as a solitary subcutaneous blue-black nodule which grows slowly.

An 18-year-old male, non-smoker, in good health, was referred to our Unit after the onset of a swelling in the right parotid region. The lesion had been present for 1 year but the patient did not seek medical attention in that time. Clinical examination showed an exophytic mass in the right parotid region measuring 20 × 20 mm. An ultrasound of the major salivary glands showed an oval lesion of the right parotid gland; contrast-enhanced MRI appeared to show an oval lesion in the right intraparotid region, approximately 20 × 25 mm, which was hypointense in T1 images, and hyperintense in T2 images, with inhomogeneous contrast-enhancement; Fine Needle Aspiration Cytology (FNAC) was indicative of a lesion with high suspicion of malignancy.

We elected to carry out a facial nerve sparing total parotidectomy, under general anesthesia, and facial reconstruction of the remaining gap with a sternocleidomastoid muscle flap. Histopathological analysis demonstrated basaloid cell proliferation beneath granulation tissue, hemorrhage, and large number of “ghost cells” with high mitotic activity. This confirmed the diagnosis of pilomatrix carcinoma. Postoperative outcome was uneventful.

我们在此报告一例罕见的右腮腺区毛基质癌,发生在一个年轻的病人。摘要毛基质癌是一种罕见的局部侵袭性肿瘤,有复发倾向。毛囊基质瘤是一种由毛囊基质细胞产生的浅表良性皮肤肿瘤,通常位于头皮、面部和上肢。临床上通常表现为生长缓慢的孤立的皮下蓝黑色结节。一名18岁男性,不吸烟,身体健康,在右侧腮腺区域出现肿胀后被转介到我科。该病变已存在1年,但患者在此期间未求医。临床检查显示右侧腮腺区长20 × 20 mm的外生性肿块。大唾液腺超声示右侧腮腺呈椭圆形病变;MRI增强示右侧腮腺内区椭圆形病灶,约20 × 25 mm, T1表现为低信号,T2表现为高信号,增强不均匀;细针吸细胞学(FNAC)提示病变高度怀疑恶性肿瘤。我们选择在全身麻醉下行保留面神经的腮腺全切除术,并用胸锁乳突肌瓣重建面部剩余间隙。组织病理学分析显示肉芽组织下基底细胞增生,出血,大量具有高有丝分裂活性的“鬼细胞”。这证实了毛基质癌的诊断。术后结果平平。
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引用次数: 0
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Oral and Maxillofacial Surgery Cases
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