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An unexpected finding: A case of papillary thyroid carcinoma within a lateral thyroglossal duct cyst 一个意想不到的发现:一例甲状腺舌管外侧囊肿内的甲状腺乳头状癌
Q3 Dentistry Pub Date : 2023-09-01 DOI: 10.1016/j.omsc.2023.100323
Pouya Namiranian , Robert S. Julian III , Brian M. Woo , Baorong Chen

Thyroglossal duct cysts (TGDCs) are the most common congenital cysts in the anterior neck. The incidence of papillary thyroid carcinoma (PTC) being present within a cyst is less than 1% and in most cases, the diagnosis is made postoperatively. We present a 60-year-old female with PTC arising from a lateral TGDC, identified in pathologic study after intra-oral excision of the cyst. Further thyroid ultrasound and fine-needle aspiration of a highly suspicious lesion at the superior pole of the left thyroid lobe showed PTC. The patient then underwent left hemithyroidectomy, isthmusectomy, ipsilateral and central neck dissection revealing PTC with ipsilateral nodal metastasis. The patient later underwent completion thyroidectomy and right neck dissection which did not reveal any additional malignant disease or nodal metastasis.

甲状舌管囊肿(TGDCs)是最常见的先天性颈部囊肿。甲状腺乳头状癌(PTC)出现在囊肿内的发生率小于1%,在大多数病例中,诊断是在手术后做出的。我们报告一位60岁的女性,在口腔内切除囊肿后,在病理研究中发现了由外侧TGDC引起的PTC。进一步的甲状腺超声和细针穿刺高度可疑的病变在左甲状腺叶上极显示PTC。患者随后行左半甲状腺切除术、峡部切除术、同侧及中央颈部清扫,发现PTC伴同侧淋巴结转移。患者后来进行了完全甲状腺切除术和右颈部清扫,未发现任何其他恶性疾病或淋巴结转移。
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引用次数: 0
A case of spindle cell hemangioma of the upper lip 上唇梭形细胞血管瘤1例
Q3 Dentistry Pub Date : 2023-09-01 DOI: 10.1016/j.omsc.2023.100327
Takeshi Yoshida , Shuu Inoue , Tatsuto Kuramoto , Akihiko Yamaguchi

Spindle cell hemangioma (SCH) is a rare benign vascular neoplasm. Its occurrence is infrequently in the oral cavity and can be mistaken for other common oral lesions such as mucocysts and fibroma. Microscopically it mimics some malignant vascular tumors and could be misdiagnosed. We report a case of SCH in the upper lip of a 49-year-old woman. The mass was diagnosed as a benign tumor and resected under local anesthesia. Histopathological findings showed dense proliferation of short spindle cells, dilated capillaries, and collagen fibers at the margin. The tumor was positive for the human erythroblast transformation-specific related gene. Thus, considering the clinical and pathological findings, a diagnosis of SCH was made. Three years have passed since the operation, and no recurrence has been observed. Our findings indicate that although SCH in the oral cavity is rare, it must be considered during the differential diagnosis of a benign lip lesion.

梭形细胞血管瘤是一种罕见的良性血管瘤。它在口腔中很少发生,可能被误认为是其他常见的口腔病变,如粘液囊肿和纤维瘤。显微镜下,它模仿了一些恶性血管肿瘤,可能会被误诊。我们报告一位49岁女性上唇SCH病例。肿块被诊断为良性肿瘤,并在局部麻醉下切除。组织病理学表现为短梭形细胞密集增殖,毛细血管扩张,边缘有胶原纤维。该肿瘤对人类成红细胞转化特异性相关基因呈阳性。因此,考虑到临床和病理结果,诊断为SCH。手术三年过去了,没有观察到复发。我们的研究结果表明,尽管口腔中的SCH很罕见,但在鉴别诊断良性唇部病变时必须考虑它。
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引用次数: 0
Rare presentation of solitary fibrous tumor in the anterior hard palate; Case report 罕见的前硬腭孤立性纤维瘤;病例报告
Q3 Dentistry Pub Date : 2023-08-26 DOI: 10.1016/j.omsc.2023.100333
Saba Hawamdeh , Gustavo Andres Grimaldi Finol , Mathias Martinez , Ismail Farag

Solitary fibrous tumors (SFT) are an uncommon group of neoplasm with an unknown origin reporting to appear in less than 2% of soft tissue tumors. Although SFT most commonly occurs in the pleura, several extra pleural sites of involvement have been reported. SFT most commonly present during the fifth and sixth decades of life, and there is no significant sex predilection. This report describes the case of a 44-year-old male patient who had unusual presentation of SFT in the anterior midline hard palate describing the morphology, histopathology, radiology management plan as well as follow up and literature review.

孤立性纤维性肿瘤(SFT)是一种不常见的肿瘤,来源不明,据报道在不到2%的软组织肿瘤中出现。虽然SFT最常发生在胸膜,但也有几个胸膜外部位受累的报道。SFT最常见于生命的第五和第六十年,并且没有明显的性别偏好。本文报告一例44岁男性患者,其前中线硬腭有异常的SFT表现,描述了形态学、组织病理学、放射学治疗方案、随访和文献复习。
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引用次数: 0
Idiopathic avascular maxillary necrosis: A case report 特发性上颌无血管性坏死1例
Q3 Dentistry Pub Date : 2023-08-25 DOI: 10.1016/j.omsc.2023.100332
S.M. Abdullah Salman , Oam Parkash , Mehak Anis , Muhammad Rameez , Hammad Ul-Haq

Osteonecrosis of the jaw (ONJ) is a rare phenomenon that usually occurs in individuals exposed to certain medications, radiation, or physical or chemical insults that ultimately result in compromised vascularity of the jaws. However, in some cases, it is difficult to pinpoint a specific risk factor that might have caused the patient to suffer this pathologic condition. Here, we are reporting a case of idiopathic maxillary necrosis for which a specific risk factor could not be established despite thorough investigations.

颌骨骨坏死(ONJ)是一种罕见的现象,通常发生在暴露于某些药物,辐射或物理或化学损伤的个体中,最终导致颌骨血管受损。然而,在某些情况下,很难确定可能导致患者遭受这种病理状况的特定风险因素。在这里,我们报告一个特发性上颌坏死的病例,尽管进行了彻底的调查,但具体的危险因素仍无法确定。
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引用次数: 0
Case report impact on orthognathic surgery for counterclockwise rotation and effect on airway, with or without temporomandibular joint total joint prostheses 顺时针旋转对正颌手术的影响及对气道的影响,有或没有颞下颌关节全关节假体
Q3 Dentistry Pub Date : 2023-08-23 DOI: 10.1016/j.omsc.2023.100325
Larry M. Wolford , Olga del Pilar Amaya Gomez

Purpose

Present case reports that have generated new treatment protocols improving treatment of patient outcomes with jaw deformities and airway compromises requiring counterclockwise rotation (CCWR) of the maxillo-mandibular complex (MMC) with or without a requirement for temporomandibular joint (TMJ) total joint prostheses (TJP). Presented are studies that verify the efficacy of these procedures.

Methods

Initial case presentations were identified in reference to CCWR of the MMC without and with TMJ total joint prostheses in cases of co-existing end-stage TMJ pathology. A non-systematic literature search was conducted to identify studies pertinent to subject matter.

Results

Two case reports are presented that have significantly affected our specialty: 1) CCWR of the MMC and effect on airway, and 2) TMJ TJP with concomitant maxillary osteotomies for CCWR of the MMC.  Forty papers were identified meeting the filtered criteria. Twenty-nine papers were excluded as case reports, philosophy, technique, or small case series. Eleven studies met the inclusion criteria and are summarized according to the data included. These studies validate the efficacy and stability of CCWR of the MMC in the presence of healthy joints as well as patients with end-stage TMJ pathology using custom TMJ TJP in conjunction with orthognathic surgery.

Conclusions

Patients with healthy TMJs can be treated with CCWR of the MMC with predictable outcomes and stability. Patients with end-stage TMJ pathology can benefit from TMJ TJP and orthognathic surgery for CCWR of the MMC with good stability, improved function, decreased pain, improved airway, and quality of life.

目的:目前的病例报告产生了新的治疗方案,改善了需要逆时针旋转(CCWR)上颌-下颌复合体(MMC)的颌骨畸形和气道妥协患者的治疗结果,并要求或不要求颞下颌关节(TMJ)全关节假体(TJP)。提出了验证这些程序的有效性的研究。方法对合并颞下颌关节终末期病变的MMC患者的CCWR进行比较。进行非系统文献检索以确定与主题相关的研究。结果2例病例报告对我们的专业有显著影响:1)MMC的CCWR及其对气道的影响;2)TMJ TJP合并上颌截骨术治疗MMC的CCWR。40篇论文符合筛选标准。29篇论文被排除在病例报告、哲学、技术或小病例系列中。11项研究符合纳入标准,并根据纳入的资料进行汇总。这些研究验证了MMC CCWR在健康关节和终末期TMJ病理患者中使用定制TMJ TJP结合正颌手术的有效性和稳定性。结论健康的颞下颌关节病患者可以采用MMC的CCWR治疗,其结果可预测且稳定。终末期TMJ病理患者可以通过TMJ TJP和正颌手术治疗MMC的CCWR,具有良好的稳定性,改善功能,减轻疼痛,改善气道和生活质量。
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引用次数: 0
Synergy of electrochemotherapy and immunotherapy in the treatment of skin squamous cell carcinoma of the head and neck 电疗与免疫疗法在头颈部皮肤鳞状细胞癌治疗中的协同作用
Q3 Dentistry Pub Date : 2023-08-19 DOI: 10.1016/j.omsc.2023.100330
Ida Barca, Francesco Ferragina, Elvis Kallaverja, Maria Giulia Cristofaro

Treatment of advanced-stage head and neck cutaneous squamous cell carcinoma is a challenge for maxillofacial surgeons, oncologists, and radiotherapists. These carcinomas respond with difficulty to systemic therapy and most of them relapse. Electrochemotherapy combines the use of cytotoxic drugs and electroporation, preserving organ function in combination with effective local control of the tumour. It can be used alone or in combination with other therapies, such as immunotherapy.

This study aims to verify whether electrochemotherapy performed with immunotherapy on head and neck squamous cell carcinoma can lead to an increase in the objective response rate. We report the case of a patient with head and neck skin squamous cell carcinoma treated with a combination of electrochemotherapy (by using both linear and finger probes) and immunotherapy (by using Cemiplimab, antibody blocking the programmed death receptor-1 – PD-1). This association has been shown to be effective both in controlling the progression of the disease, and in reducing the symptomatology of the patient (reduction of pain and bleeding), leading to an improvement in the quality of life.

晚期头颈部皮肤鳞状细胞癌的治疗对颌面外科医生、肿瘤学家和放射治疗师来说是一个挑战。这些癌对全身治疗反应困难,大多数复发。电疗结合使用细胞毒性药物和电穿孔,在保留器官功能的同时有效地局部控制肿瘤。它可以单独使用,也可以与其他疗法(如免疫疗法)联合使用。本研究旨在验证电化疗联合免疫治疗头颈部鳞状细胞癌是否能提高客观有效率。我们报告了一例头颈部皮肤鳞状细胞癌患者,采用化疗(使用线性和手指探针)和免疫治疗(使用阻断程序性死亡受体-1 - PD-1的抗体Cemiplimab)联合治疗。这种联系已被证明在控制疾病进展和减轻患者症状(减轻疼痛和出血)方面是有效的,从而改善了生活质量。
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引用次数: 0
Oral metastasis of a human chorionic gonadotrophin secreting primary hepatic carcinoma; A case report observed at the Yaoundé University Teaching Hospital 人绒毛膜促性腺激素分泌型原发性肝癌的口腔转移;雅温得大学教学医院的病例报告
Q3 Dentistry Pub Date : 2023-07-01 DOI: 10.1016/j.omsc.2023.100321
Zilefac Brian Ngokwe, Ntep Ntep David Bienvenue, Endalle Ewoudou Catherine, Nokam Kamdem Stephane, Mandeng Chanelle Valérie, Mballa Amougou Jean Claude
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引用次数: 0
A case of spindle cell hemangioma of the upper lip 上唇梭形细胞血管瘤1例
Q3 Dentistry Pub Date : 2023-07-01 DOI: 10.1016/j.omsc.2023.100327
Takeshi Yoshida, Shuu Inoue, Tatsuto Kuramoto, A. Yamaguchi
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引用次数: 0
Multidisciplinary management of an advanced mandibular ameloblastoma: Etiopathogenesis, surgical management and prosthetic rehabilitation 晚期下颌成釉细胞瘤的多学科治疗:发病机制、手术治疗和假肢康复
Q3 Dentistry Pub Date : 2023-06-01 DOI: 10.1016/j.omsc.2023.100296
Jeffrey W. Chadwick , Sonia Ruo Chen Huang , Ali Khadivi , Karl K. Cuddy

Background

The ameloblastoma is a benign but locally aggressive epithelial odontogenic neoplasm. Although rare, the ameloblastoma is the most common odontogenic tumor associated with the maxillofacial complex which possesses a significant propensity for local recurrence in the setting of conservative treatment. Concordantly, definitive therapy is predicated on wide surgical excision with reconstruction of ablative defects dictated by the resultant tissue defects. The purpose of this report is to highlight specific treatment and reconstructive challenges, emphasizing the essential need for collaborative patient care within a large multidisciplinary team.

Case description

A 31-year-old Vietnamese-speaking male was referred for management of an extensive ameloblastoma associated with the left mandible. Management consisted of a bilateral composite mandibular resection and reconstruction via free tissue transfer utilizing an osteocutaneous fibular free flap. Histopathologic analysis confirmed the diagnosis of a conventional ameloblastoma. Delayed oral rehabilitation employing virtual surgical planning to facilitate the placement of endosseous implants with immediate loading of a fixed acrylic prosthesis was accomplished in the post-operative period without any evidence of recurrence.

Practical implications

Multidisciplinary collaboration in the setting of advanced odontogenic tumors is paramount in enhancing treatment outcomes. This case strengthens the need for accurate and rapid diagnosis in the primary care setting with collaborative interprofessional management utilizing advances in digital technologies to optimize both functional and aesthetic outcomes which have significant influence over long-term quality-of-life.

成釉细胞瘤是一种良性但局部侵袭性的上皮性牙源性肿瘤。虽然罕见,但成釉细胞瘤是最常见的与颌面复合体相关的牙源性肿瘤,在保守治疗中具有明显的局部复发倾向。一致地,最终的治疗是基于广泛的手术切除和消融缺陷的重建,由此产生的组织缺陷。本报告的目的是强调具体的治疗和重建挑战,强调在一个大型多学科团队中协作患者护理的基本需求。病例描述:一名31岁的越南语男性因左下颌骨广泛的成釉细胞瘤而接受治疗。治疗包括双侧复合下颌骨切除术和利用骨皮腓骨自由皮瓣进行游离组织移植重建。组织病理学分析证实了常规成釉细胞瘤的诊断。延迟口腔康复采用虚拟手术计划,以方便放置内腔种植体,并立即加载固定丙烯酸假体,在术后完成,无复发迹象。临床意义:在晚期牙源性肿瘤的治疗中,多学科合作对提高治疗效果至关重要。本案例强调了在初级保健环境中对准确和快速诊断的需求,利用先进的数字技术进行跨专业协作管理,以优化对长期生活质量有重大影响的功能和美学结果。
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引用次数: 0
Hypoglossal nerve injury following local anesthetic injection: A case report and literature review 局麻注射后舌下神经损伤1例并文献复习
Q3 Dentistry Pub Date : 2023-06-01 DOI: 10.1016/j.omsc.2023.100300
Andrew J. Deek , Christopher Scott , Michael Foster , Jack E. Gotcher Jr.

Hypoglossal nerve injury is a known complication of oral intubation, otolaryngology procedures, and trauma. More rarely, hypoglossal nerve injury has been described as a complication of dental procedures. While iatrogenic damage to the inferior alveolar nerve has been extensively described in the oral and maxillofacial surgery literature, a paucity of literature can be found related to 12th cranial nerve complications. This case report aims to describe a case presenting to our office and the available treatment for patients suffering from this pathology.

舌下神经损伤是已知的口腔插管、耳鼻喉科手术和创伤的并发症。更罕见的是,舌下神经损伤被描述为牙科手术的并发症。虽然医源性下牙槽神经损伤在口腔颌面外科文献中有广泛的描述,但与第12颅神经并发症相关的文献很少。本病例报告的目的是描述一个病例呈现到我们的办公室和可用的治疗患者患有这种病理。
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引用次数: 0
期刊
Oral and Maxillofacial Surgery Cases
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