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Evaluation of the efficacy of three distinct lip repositioning techniques and identification of the approach associated with the lowest relapse rate. A six-month follow-up case report 评估三种不同的唇部复位技术的疗效,并确定复发率最低的方法。6个月随访病例报告
Q3 Dentistry Pub Date : 2025-12-01 Epub Date: 2025-09-11 DOI: 10.1016/j.omsc.2025.100423
Mohamad A. Alhomsi, Issa B. Wehbeh

Background

A beautiful smile is a key element of facial aesthetics, with an average gingival display of 1–3 mm in smile position. When gingival visibility exceeds this range, it is defined as a gummy smile. This condition may result from skeletal, dentoalveolar, or soft tissue factors.

Case description

Three patients with mild gummy smile were treated using different approaches: (i) traditional lip repositioning surgery, (ii) modified lip repositioning surgery, and (iii) Botox injection. Patients were monitored for two weeks to assess postoperative complications. Follow-up evaluations at two weeks, one month, three months, and six months assessed gingival exposure and relapse.

Conclusion

The modified lip repositioning procedure demonstrated greater stability between the three- and six-month follow-ups, with the least relapse, although it was associated with more postoperative complications. Botox was the most preferred option due to its non-invasive nature.
美丽的微笑是面部美学的关键元素,在微笑位置牙龈平均显示1-3毫米。当牙龈的可见度超过这个范围时,就被定义为粘牙微笑。这种情况可能是由骨骼、牙槽牙或软组织因素引起的。病例描述对3例轻度粘笑患者采用不同的治疗方法:(i)传统的唇部复位手术,(ii)改良的唇部复位手术和(iii)注射肉毒杆菌。对患者进行为期两周的监测以评估术后并发症。随访2周,1个月,3个月和6个月评估牙龈暴露和复发。结论改良的唇部复位手术在3 ~ 6个月的随访中表现出更大的稳定性,复发率最低,但术后并发症较多。肉毒杆菌素是最受欢迎的选择,因为它的非侵入性。
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引用次数: 0
Rehabilitation of the atrophic maxilla: Guided Le Fort I maxillary advancement and zygomatic implants with and immediate loading 萎缩上颌的康复:引导Le Fort I上颌前进和颧种植体与即刻负荷
Q3 Dentistry Pub Date : 2025-12-01 Epub Date: 2025-09-11 DOI: 10.1016/j.omsc.2025.100422
Rémy Raphael , Dimitri Pascual

Introduction

The full-arch rehabilitation of the atrophic maxilla using four zygomatic implants (ZI) has become a widespread solution, allowing us to bypass bone grafting procedures. However, the palatal prosthetic emergences inherent to the skeletal discrepancy cause significant discomfort for patients due to prosthetic compensations volume.

Observation

A 60-year-old patient, completely edentulous at the maxillary with severe atrophy and a skeletal Class III, was referred to us for full rehabilitation. We use an innovant surgical guide to perform the Le Fort I osteotomy, placement of four zygomatic implants, and immediate loading of a screw-retained Zirconia bridge without prosthetic compensation in one single surgery virtually planned.

Conclusion

Zygomatic implant and orthognathic rehabilitation, using a custom surgical guide, offers an accurate solution to restore in a single surgery, the oral function with an immediate loading prothesis when the maxilla atrophy is severe in skeletal Class III.
使用四个颧植入物(ZI)对萎缩的上颌骨进行全弓康复已经成为一种广泛的解决方案,使我们能够绕过植骨手术。然而,由于假体代偿体积的差异,腭假体出现固有的骨骼差异会给患者带来明显的不适。一位60岁的患者,上颌完全无牙,严重萎缩,骨骼为III级,被转介到我们进行完全康复。我们使用一种创新的手术指南,在一次手术中完成Le Fort I型截骨术,放置四个颧骨植入物,并立即加载螺钉保留的氧化锆桥,而无需假体补偿。结论颧骨种植和正颌康复,采用定制的手术指导,可以在颌骨严重萎缩的情况下,单次手术修复即刻加载假体的口腔功能。
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引用次数: 0
Angina bullosa hemorrhagica: A case report and review of the literature 大疱性出血性心绞痛1例报告及文献复习
Q3 Dentistry Pub Date : 2025-09-01 Epub Date: 2025-07-12 DOI: 10.1016/j.omsc.2025.100412
Hassan El-Awour , Kinda Allaham , Mohammed Inam Ullah Khan
Here we present a case of Angina Bullosa Hemorrhagica (ABH) and review the literature highlighting its features, differentiation diagnosis from similar lesions, management considerations, and treatment options. Furthermore, we present a treatment algorithm for managing cases of this rare disorder. ABH lesions commonly manifest on the palate, tongue, buccal mucosa, lips, the floor of the mouth, and uvula. ABH range in size, from 4 to 30 mm in diameter. ABH lesions are generally self-limiting and resolve within a few days without scarring. Management recommendations may include supportive therapy for small lesions, incision for large bulla and continued palliative therapy using mouthrinses and analgesics. Though, ABH is a rare disorder, general dental practitioners ought to be aware of it. This report provides guidance on diagnosis, management and investigations in hopes to avoid ill-informed or unnecessary treatments.
在此,我们报告一例大疱性出血性心绞痛(ABH),并回顾文献,强调其特征,与类似病变的鉴别诊断,管理注意事项和治疗方案。此外,我们提出了一种治疗算法来管理这种罕见疾病的病例。ABH病变通常表现在上颚、舌头、颊粘膜、嘴唇、口腔底和小舌。ABH的尺寸范围,从直径4到30毫米。ABH病变通常是自限性的,在几天内消退,不会留下疤痕。治疗建议包括对小病变的支持治疗,对大球囊的切开治疗和使用止疼药和止痛药的持续姑息治疗。虽然,ABH是一种罕见的疾病,普通牙科医生应该意识到这一点。本报告提供了诊断、管理和调查方面的指导,希望能避免不了解情况或不必要的治疗。
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引用次数: 0
The interplay of soft tissue and osseous structures in bifid mandibular condyle: Implications for diagnosis and treatment. Case series and literature review 软组织和骨性结构在下颌髁的相互作用:对诊断和治疗的意义。病例系列和文献回顾
Q3 Dentistry Pub Date : 2025-09-01 Epub Date: 2025-08-07 DOI: 10.1016/j.omsc.2025.100415
Gustavo Andres Grimaldi Finol , Alaa Abdulsattar Kadhim Al-Taie , Renan Elsadig Ibrahem Aadam , Ismail Farag , Abdul-Aziz ALaqeeli
Bifid mandibular condyle (BMC) is a rare developmental or acquired anomaly of the temporomandibular joint (TMJ), characterized by the presence of a duplicated condylar head. Although often asymptomatic and discovered incidentally on imaging, BMC can be associated with TMJ dysfunction, facial asymmetry, and a history of trauma or developmental disturbances. The clinical significance of BMC remains poorly understood, with controversies surrounding its etiology, classification, and management. This article presents a comprehensive literature review on the current understanding of BMC, supported by the presentation of a unique clinical case involving a symptomatic patient diagnosed through advanced imaging modalities. The diagnostic process, clinical presentation, and treatment approach are detailed to highlight the role of thorough evaluation and multidisciplinary management. Our findings suggest that while conservative management remains the mainstay in asymptomatic cases, individualized approaches are essential when functional disturbances are present. Further studies are warranted to clarify long-term outcomes and to standardize diagnostic and therapeutic protocols for BMC within maxillofacial practice.
双裂下颌髁(BMC)是一种罕见的发育或获得性颞下颌关节(TMJ)异常,其特征是存在重复的髁头。虽然BMC通常无症状且在影像学上偶然发现,但它可能与颞下颌关节功能障碍、面部不对称、创伤史或发育障碍有关。BMC的临床意义仍然知之甚少,围绕其病因、分类和管理存在争议。本文介绍了一个独特的临床病例,该病例涉及一位通过先进的成像方式诊断出有症状的患者,并对目前对BMC的理解进行了全面的文献回顾。诊断过程,临床表现和治疗方法详细强调全面评估和多学科管理的作用。我们的研究结果表明,虽然保守治疗仍然是无症状病例的主流,但当存在功能障碍时,个性化治疗是必不可少的。进一步的研究是必要的,以澄清长期结果和标准化的诊断和治疗方案BMC在颌面外科实践。
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引用次数: 0
The trinity of chronic kidney failure, hyperparathyroidism, and brown tumors: a case report 慢性肾衰竭、甲状旁腺功能亢进和棕色肿瘤三位一体:1例报告
Q3 Dentistry Pub Date : 2025-09-01 Epub Date: 2025-08-22 DOI: 10.1016/j.omsc.2025.100417
Alamira haya Salloum , Nayar Khadro , Iyad Ali , Mounzer Assad , Zuheir Alshehabi

Introduction

Chronic kidney disease (CKD) is an irreversible progressive glomerular disease, and it can cause many complications like osteodystrophy, hyperparathyroidism (HPT), or bone lesions such as Brown Tumors (BT)
BTs are rare slow-growing lesions in skeletal and facial bones and are benign.
This paper describes a patient with tertiary hyperparathyroidism (THPT) and CKD-MBD who developed a large maxillary BT.

Case presentation

A 28-year-old male presented with swelling in the maxillary bone caused by secondary hyperparathyroidism (SHPT) after 14 years of chronic kidney disease (CKD). Radiological examinations confirmed the presence of a bone lesion localized to the maxillary bone, indicating a tumor, followed by histological tests confirmed the tumor was a brown tumor and the role of CKD and SHPT hypothesis involvement. The tumor was treated surgically after controlling the other underlying conditions.

Discussion

The impaired kidney function in Chronic kidney disease (CKD) leads to vitamin D deficiency and abnormal calcium and phosphorus levels, which stimulate the parathyroid glands to overproduce parathyroid hormone (PTH), and alteration in bone resorption and formation leading to bone lesions like BTs.
The diagnosis of brown Tumors is quite challenging and usually requires a combination of clinical and laboratory examination with imaging.
The cornerstone in treating BTs is managing the underlying HPT, which may involve medication, surgery, or both.

Conclusion

Brown Tumors are a late complication of hyperparathyroidism and chronic kidney disease. A thorough medical history is essential for early diagnosis and appropriate treatment of BTs.
慢性肾脏疾病(CKD)是一种不可逆的进行性肾小球疾病,它可以引起许多并发症,如骨营养不良、甲状旁腺功能亢进(HPT)或骨病变,如棕色肿瘤(BT), BT是骨骼和面部骨骼中罕见的缓慢生长病变,是良性的。本文报告一位患有慢性肾脏疾病(CKD) 14年后继发性甲状旁腺功能亢进症(SHPT)的28岁男性患者,上颌骨肿胀。影像学检查证实上颌骨存在骨病变,提示肿瘤,随后组织学检查证实肿瘤为棕色肿瘤,假设CKD和SHPT的作用涉及。在控制了其他基础条件后,对肿瘤进行了手术治疗。慢性肾脏疾病(CKD)的肾功能受损导致维生素D缺乏和钙磷水平异常,从而刺激甲状旁腺过量产生甲状旁腺激素(PTH),改变骨吸收和形成,导致骨病变,如BTs。棕色肿瘤的诊断相当具有挑战性,通常需要结合临床和实验室检查以及影像学检查。治疗bt的基石是控制潜在的HPT,这可能涉及药物、手术或两者兼而有之。结论褐色肿瘤是甲状旁腺功能亢进和慢性肾脏疾病的晚期并发症。全面的病史对于早期诊断和适当治疗bt至关重要。
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引用次数: 0
Evaluation of the effectiveness of anterior segmental maxillary osteotomy in management of anterior vertical maxillary excess associated with gummy smile: A clinical study 上颌前节段截骨术治疗上颌前垂直过度伴粘笑的临床研究
Q3 Dentistry Pub Date : 2025-09-01 Epub Date: 2025-08-05 DOI: 10.1016/j.omsc.2025.100414
Mohammad Kouja, Abdul Karim Khalil
To evaluate the effectiveness of anterior segmental maxillary osteotomy in improving The amount of gingival exposure (above incisors and above canines) and the measurement of the nasolabial angle and increasing patient satisfaction in cases of excessive vertical growth of the upper jaw associated with a gummy smile.

Materials and methods

10 female patients, aged 20–34 years, were diagnosed with anterior vertical maxillary excess combined with a gummy smile. They underwent anterior segmental maxillary osteotomy using digital three-dimensional planning. Gingival exposure above the incisors and canines and the nasolabial angle were measured. Patient satisfaction was assessed using a numerical scale from 1 to 5 six months post-surgery.

Results

The findings demonstrated a statistically significant reduction in gingival exposure (from 7.00 mm to 1.20 mm above incisors, with an 97.14 % improvement) and (from 6.30 mm to 1.40 mm, with a 93.65 % improvement).And nasolabial angle(from 84.24° to 98.77° with 92.20 %).The average patient satisfaction score was 4.70 out of 5, with a low standard deviation (0.48), indicating a high level of satisfaction consistency among the patients.

Conclusion

Anterior segmental maxillary osteotomy is an effective and safe technique for improving gingival exposure over the maxillary incisors and canines, optimizing the nasolabial angle, and enhancing patient satisfaction in cases of excessive vertical maxillary growth associated with a gummy smile, particularly when performed with digital planning.
评价上颌前节段截骨术对提高上颌垂直生长过度伴粘笑患者牙龈暴露量(门牙上和犬齿上)和鼻唇角测量的效果,提高患者满意度。材料与方法10例女性患者,年龄20 ~ 34岁,诊断为上颌前垂直增生合并粘牙。他们采用数字三维规划进行上颌前段截骨术。测量门齿和犬齿以上牙龈暴露量和鼻唇角。术后1 - 6个月采用数值量表评估患者满意度。结果龈外露(从门牙以上7.00 mm减少到1.20 mm,改善97.14%)和(从6.30 mm减少到1.40 mm,改善93.65%)均有统计学意义。鼻唇角(84.24°~ 98.77°)占92.20%。患者满意度平均得分为4.70分(满分5分),标准差较低(0.48分),表明患者满意度一致性较高。结论上颌前节段截骨术是一种安全有效的方法,可以改善上颌切牙和犬齿的牙龈暴露,优化鼻唇角,提高上颌垂直生长过度伴粘笑患者的满意度,特别是在数字计划下。
{"title":"Evaluation of the effectiveness of anterior segmental maxillary osteotomy in management of anterior vertical maxillary excess associated with gummy smile: A clinical study","authors":"Mohammad Kouja,&nbsp;Abdul Karim Khalil","doi":"10.1016/j.omsc.2025.100414","DOIUrl":"10.1016/j.omsc.2025.100414","url":null,"abstract":"<div><div>To evaluate the effectiveness of anterior segmental maxillary osteotomy in improving The amount of gingival exposure (above incisors and above canines) and the measurement of the nasolabial angle and increasing patient satisfaction in cases of excessive vertical growth of the upper jaw associated with a gummy smile.</div></div><div><h3>Materials and methods</h3><div>10 female patients, aged 20–34 years, were diagnosed with anterior vertical maxillary excess combined with a gummy smile. They underwent anterior segmental maxillary osteotomy using digital three-dimensional planning. Gingival exposure above the incisors and canines and the nasolabial angle were measured. Patient satisfaction was assessed using a numerical scale from 1 to 5 six months post-surgery.</div></div><div><h3>Results</h3><div>The findings demonstrated a statistically significant reduction in gingival exposure (from 7.00 mm to 1.20 mm above incisors, with an 97.14 % improvement) and (from 6.30 mm to 1.40 mm, with a 93.65 % improvement).And nasolabial angle(from 84.24° to 98.77° with 92.20 %).The average patient satisfaction score was 4.70 out of 5, with a low standard deviation (0.48), indicating a high level of satisfaction consistency among the patients.</div></div><div><h3>Conclusion</h3><div>Anterior segmental maxillary osteotomy is an effective and safe technique for improving gingival exposure over the maxillary incisors and canines, optimizing the nasolabial angle, and enhancing patient satisfaction in cases of excessive vertical maxillary growth associated with a gummy smile, particularly when performed with digital planning.</div></div>","PeriodicalId":38030,"journal":{"name":"Oral and Maxillofacial Surgery Cases","volume":"11 3","pages":"Article 100414"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144770944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Occult papillary thyroid carcinoma presenting as parapharyngeal space mass: A case report and literature review 隐匿性甲状腺乳头状癌表现为咽旁间隙肿块:1例报告并文献复习
Q3 Dentistry Pub Date : 2025-09-01 Epub Date: 2025-05-24 DOI: 10.1016/j.omsc.2025.100402
Fawaz Alotaibi , Harish Tummala , Mitchell Naito , Yousef Alshamrani
Papillary thyroid carcinoma presenting as a parapharyngeal mass is uncommon clinical presentation1,2. Papillary thyroid cancer is the most common primary thyroid cancer (80–90 % of cases)17. 20–50 % of cases have lymph node metastasis4. Superior thyroid lesions usually metastasize through superior pretracheal and cervical nodes while inferior thyroid and isthmus drainage travel via the paratracheal and deep cervical nodes17. Parapharyngeal space (PPS) tumors are rare and represent about 0.5 % of all head and neck tumors1,2. We report a case of 59 years-old man who presented initially with left parapharyngeal mass for about four months and a chief complaint of dysphagia. Exam revealed a submucosal 4 cm mass in the oropharyngeal wall, no tumor was palpable in the neck and his physical examination was otherwise unremarkable. Preoperative work up was completed, and Fine Needle Aspiration (FNA) was inconclusive. The mass was excised via transcervical-mandibular swing approach and a diagnosis of papillary thyroid carcinoma was rendered. Subsequently, the patient underwent a total thyroidectomy and neck dissection. This case report highlights the unusual metastasis to parapharyngeal space from occult papillary thyroid carcinoma, reviews the lymphatic drainage system of the head and neck responsible for this route of metastasis, recommendations for preoperative imaging, surgical treatment, and adjuvant treatment of this uncommon presentation.
甲状腺乳头状癌表现为咽旁肿块是罕见的临床表现1,2。甲状腺乳头状癌是最常见的原发性甲状腺癌(占病例的80 - 90%)17。20 - 50%的病例有淋巴结转移4。上甲状腺病变通常通过上气管前淋巴结和颈淋巴结转移,而下甲状腺和峡部引流则通过气管旁淋巴结和颈深部淋巴结转移17。咽旁间隙(PPS)肿瘤很少见,约占头颈部肿瘤的0.5% 1,2。我们报告一个59岁的男性病例,他最初表现为左侧咽旁肿块约4个月,主诉为吞咽困难。检查发现口咽壁黏膜下4厘米肿块,颈部未见肿瘤,其他体格检查无明显异常。术前工作完成,细针抽吸(FNA)不确定。肿块经经颈-下颌摆动入路切除,诊断为甲状腺乳头状癌。随后,患者接受了甲状腺全切除术和颈部清扫术。本病例报告强调隐匿性甲状腺乳头状癌向咽旁间隙的不寻常转移,回顾头颈部淋巴引流系统对这种转移途径的影响,建议术前影像学、手术治疗和辅助治疗这种不寻常的表现。
{"title":"Occult papillary thyroid carcinoma presenting as parapharyngeal space mass: A case report and literature review","authors":"Fawaz Alotaibi ,&nbsp;Harish Tummala ,&nbsp;Mitchell Naito ,&nbsp;Yousef Alshamrani","doi":"10.1016/j.omsc.2025.100402","DOIUrl":"10.1016/j.omsc.2025.100402","url":null,"abstract":"<div><div>Papillary thyroid carcinoma presenting as a parapharyngeal mass is uncommon clinical presentation<sup>1,2</sup>. Papillary thyroid cancer is the most common primary thyroid cancer (80–90 % of cases)<sup>17</sup>. 20–50 % of cases have lymph node metastasis<sup>4</sup>. Superior thyroid lesions usually metastasize through superior pretracheal and cervical nodes while inferior thyroid and isthmus drainage travel via the paratracheal and deep cervical nodes<sup>17</sup>. Parapharyngeal space (PPS) tumors are rare and represent about 0.5 % of all head and neck tumors<sup>1,2</sup>. We report a case of 59 years-old man who presented initially with left parapharyngeal mass for about four months and a chief complaint of dysphagia. Exam revealed a submucosal 4 cm mass in the oropharyngeal wall, no tumor was palpable in the neck and his physical examination was otherwise unremarkable. Preoperative work up was completed, and Fine Needle Aspiration (FNA) was inconclusive. The mass was excised via transcervical-mandibular swing approach and a diagnosis of papillary thyroid carcinoma was rendered. Subsequently, the patient underwent a total thyroidectomy and neck dissection. This case report highlights the unusual metastasis to parapharyngeal space from occult papillary thyroid carcinoma, reviews the lymphatic drainage system of the head and neck responsible for this route of metastasis, recommendations for preoperative imaging, surgical treatment, and adjuvant treatment of this uncommon presentation.</div></div>","PeriodicalId":38030,"journal":{"name":"Oral and Maxillofacial Surgery Cases","volume":"11 3","pages":"Article 100402"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144205666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Iatrogenic intra-temporomandibular joint emphysema during injection: A case report 注射时医源性颞下颌关节内肺气肿1例
Q3 Dentistry Pub Date : 2025-09-01 Epub Date: 2025-05-26 DOI: 10.1016/j.omsc.2025.100405
Asaad Shehada, Mazen Zenati
The temporomandibular joint has a variation in its atmospheric pressure during the mouth movement, although the intra-articular injection is widely used as one of the management strategies for reducing the pain and enhancing the mouth movement range, there are atmospheric fluctuations in the joint space due to make a passage between this closed spaces and the external medium when the needle inserted into the joint capsule. This report presents iatrogenic emphysema in two cases, while this emphysema is absent in a different case.
颞下颌关节在口腔运动过程中存在大气压的变化,尽管关节内注射被广泛用于减轻疼痛和增加口腔运动范围的治疗策略之一,但当针头插入关节囊时,由于关节间隙与外部介质之间存在通道,因此关节间隙存在大气波动。本报告报告了两例医源性肺气肿,而另一例无此肺气肿。
{"title":"Iatrogenic intra-temporomandibular joint emphysema during injection: A case report","authors":"Asaad Shehada,&nbsp;Mazen Zenati","doi":"10.1016/j.omsc.2025.100405","DOIUrl":"10.1016/j.omsc.2025.100405","url":null,"abstract":"<div><div>The temporomandibular joint has a variation in its atmospheric pressure during the mouth movement, although the intra-articular injection is widely used as one of the management strategies for reducing the pain and enhancing the mouth movement range, there are atmospheric fluctuations in the joint space due to make a passage between this closed spaces and the external medium when the needle inserted into the joint capsule. This report presents iatrogenic emphysema in two cases, while this emphysema is absent in a different case.</div></div>","PeriodicalId":38030,"journal":{"name":"Oral and Maxillofacial Surgery Cases","volume":"11 3","pages":"Article 100405"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144166766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Primary sclerosing fibroinflammatory pseudotumor of the maxillary sinus misdiagnosed as migraine: A case report 上颌窦原发性硬化性纤维炎性假瘤误诊为偏头痛1例
Q3 Dentistry Pub Date : 2025-09-01 Epub Date: 2025-07-05 DOI: 10.1016/j.omsc.2025.100411
Safwan Salih, Sadeq Qanah, Fadi Nahhab
The head and neck region is a complex anatomical area where overlapping structures and nonspecific symptoms often make accurate diagnosis challenging. Facial pain, in particular, is a common yet ambiguous symptom frequently attributed to prevalent conditions like migraine, which can delay recognition of less common but clinically significant diseases. One such condition is Primary Sclerosing Fibroinflammatory Pseudotumor—a rare, benign lesion that can mimic malignancy both clinically and radiologically.We present the case of an 18-year-old female with chronic facial pain and globe displacement, misdiagnosed as migraine for four years. Imaging revealed a mass in the maxillary sinus with bone erosion and orbital involvement. A core needle biopsy was inconclusive, and definitive diagnosis was achieved only after surgical excision. Histopathological and immunohistochemical analysis confirmed Primary Sclerosing Fibroinflammatory Pseudotumor. The patient experienced substantial clinical improvement following combined surgical and corticosteroid therapy. This case highlights the importance of including rare pathologies in the differential diagnosis of maxillofacial masses and demonstrates the value of thorough investigation when symptoms persist despite standard treatment.
头颈部是一个复杂的解剖区域,其中重叠的结构和非特异性症状往往使准确诊断具有挑战性。尤其是面部疼痛,是一种常见但模棱两可的症状,通常归因于偏头痛等常见疾病,这可能会延迟对不太常见但具有临床意义的疾病的识别。其中一种情况是原发性硬化性纤维炎性假瘤,这是一种罕见的良性病变,在临床和放射学上都能模仿恶性肿瘤。我们提出的情况下,18岁的女性慢性面部疼痛和全球位移,误诊为偏头痛四年。影像学显示上颌窦肿块伴骨侵蚀及眼眶受累。核心穿刺活检不确定,只有在手术切除后才得到明确诊断。组织病理学和免疫组化分析证实原发性硬化性纤维炎性假瘤。在手术和皮质类固醇联合治疗后,患者的临床状况得到了显著改善。本病例强调了在颌面部肿块鉴别诊断中包括罕见病理的重要性,并证明了在标准治疗后症状仍然存在时进行彻底检查的价值。
{"title":"Primary sclerosing fibroinflammatory pseudotumor of the maxillary sinus misdiagnosed as migraine: A case report","authors":"Safwan Salih,&nbsp;Sadeq Qanah,&nbsp;Fadi Nahhab","doi":"10.1016/j.omsc.2025.100411","DOIUrl":"10.1016/j.omsc.2025.100411","url":null,"abstract":"<div><div>The head and neck region is a complex anatomical area where overlapping structures and nonspecific symptoms often make accurate diagnosis challenging. Facial pain, in particular, is a common yet ambiguous symptom frequently attributed to prevalent conditions like migraine, which can delay recognition of less common but clinically significant diseases. One such condition is Primary Sclerosing Fibroinflammatory Pseudotumor—a rare, benign lesion that can mimic malignancy both clinically and radiologically.We present the case of an 18-year-old female with chronic facial pain and globe displacement, misdiagnosed as migraine for four years. Imaging revealed a mass in the maxillary sinus with bone erosion and orbital involvement. A core needle biopsy was inconclusive, and definitive diagnosis was achieved only after surgical excision. Histopathological and immunohistochemical analysis confirmed Primary Sclerosing Fibroinflammatory Pseudotumor. The patient experienced substantial clinical improvement following combined surgical and corticosteroid therapy. This case highlights the importance of including rare pathologies in the differential diagnosis of maxillofacial masses and demonstrates the value of thorough investigation when symptoms persist despite standard treatment<strong>.</strong></div></div>","PeriodicalId":38030,"journal":{"name":"Oral and Maxillofacial Surgery Cases","volume":"11 3","pages":"Article 100411"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144581178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tumor Transformation: Case of conversion of Ossifying Fibroma to Osteosarcoma post-excision in a young male 肿瘤转化:一例年轻男性骨化纤维瘤切除术后转化为骨肉瘤
Q3 Dentistry Pub Date : 2025-09-01 Epub Date: 2025-07-10 DOI: 10.1016/j.omsc.2025.100409
Sagar Rane, Nitin Bhola, Chetan Gupta
Ossifying fibroma (OF) is a benign fibro-osseous tumor characterized by slow growth and a low recurrence risk, primarily affecting the mandible in young females. Although OF is typically non-invasive, rare cases demonstrate locally aggressive behavior, requiring surgical resection. Post-surgical transformation of into osteosarcoma, a rare malignancy with a prevalence of 0.7 per million in the jaw, is exceptionally uncommon. This report presents a rare case of a 28-year-old male initially diagnosed with ossifying fibroma, managed surgically through excision and reconstruction with an iliac crest graft. Despite achieving negative margins, the lesion underwent malignant transformation into fibroblastic osteosarcoma within a month, presenting diagnostic and therapeutic challenges.
The malignant transformation was confirmed through histopathological and immunohistochemical evaluations, revealing a high Ki-67 labeling index (60 %), indicative of aggressive tumor behavior. Following multidisciplinary tumor board discussions, the patient underwent extensive surgical management, including composite resection, segmental mandibulectomy, neck dissection, and microvascular reconstruction with a free fibula osteocutaneous flap. Despite its rarity, this case highlights the need for vigilant follow-up and comprehensive diagnostic workups for recurrent or progressive lesions post-OF resection.
This report contributes to the limited literature on malignant transformation in fibro-osseous lesions, emphasizing the importance of differentiating benign conditions from low-grade malignancies and discussing the role of surgical intervention in such transformations. Further research is required to elucidate the mechanisms of transformation, optimize management strategies, and improve outcomes for patients with similar rare pathologies.
骨化纤维瘤(OF)是一种生长缓慢、复发风险低的良性纤维骨肿瘤,主要影响年轻女性的下颌骨。虽然OF通常是非侵入性的,但很少有病例表现出局部侵袭性行为,需要手术切除。骨肉瘤是一种罕见的恶性肿瘤,在颌骨中发病率为百万分之0.7,非常罕见。本文报告一例罕见的28岁男性患者,最初诊断为骨化性纤维瘤,通过手术切除和髂骨移植重建。尽管边缘呈阴性,但病变在一个月内恶性转化为纤维母细胞骨肉瘤,给诊断和治疗带来了挑战。通过组织病理学和免疫组化评价证实了恶性转化,显示Ki-67标记指数高(60%),表明肿瘤具有侵袭性行为。在多学科肿瘤委员会讨论后,患者接受了广泛的手术治疗,包括复合切除术、下颌骨节段性切除术、颈部剥离术和腓骨骨皮皮瓣重建微血管。尽管罕见,该病例强调了对肿瘤切除术后复发或进展性病变的警惕随访和全面诊断的必要性。本报告补充了有限的关于纤维骨病变恶性转化的文献,强调了区分良性和低级别恶性肿瘤的重要性,并讨论了手术干预在这种转化中的作用。需要进一步的研究来阐明转化机制,优化管理策略,改善类似罕见病理患者的预后。
{"title":"Tumor Transformation: Case of conversion of Ossifying Fibroma to Osteosarcoma post-excision in a young male","authors":"Sagar Rane,&nbsp;Nitin Bhola,&nbsp;Chetan Gupta","doi":"10.1016/j.omsc.2025.100409","DOIUrl":"10.1016/j.omsc.2025.100409","url":null,"abstract":"<div><div>Ossifying fibroma (OF) is a benign fibro-osseous tumor characterized by slow growth and a low recurrence risk, primarily affecting the mandible in young females. Although OF is typically non-invasive, rare cases demonstrate locally aggressive behavior, requiring surgical resection. Post-surgical transformation of into osteosarcoma, a rare malignancy with a prevalence of 0.7 per million in the jaw, is exceptionally uncommon. This report presents a rare case of a 28-year-old male initially diagnosed with ossifying fibroma, managed surgically through excision and reconstruction with an iliac crest graft. Despite achieving negative margins, the lesion underwent malignant transformation into fibroblastic osteosarcoma within a month, presenting diagnostic and therapeutic challenges.</div><div>The malignant transformation was confirmed through histopathological and immunohistochemical evaluations, revealing a high Ki-67 labeling index (60 %), indicative of aggressive tumor behavior. Following multidisciplinary tumor board discussions, the patient underwent extensive surgical management, including composite resection, segmental mandibulectomy, neck dissection, and microvascular reconstruction with a free fibula osteocutaneous flap. Despite its rarity, this case highlights the need for vigilant follow-up and comprehensive diagnostic workups for recurrent or progressive lesions post-OF resection.</div><div>This report contributes to the limited literature on malignant transformation in fibro-osseous lesions, emphasizing the importance of differentiating benign conditions from low-grade malignancies and discussing the role of surgical intervention in such transformations. Further research is required to elucidate the mechanisms of transformation, optimize management strategies, and improve outcomes for patients with similar rare pathologies.</div></div>","PeriodicalId":38030,"journal":{"name":"Oral and Maxillofacial Surgery Cases","volume":"11 3","pages":"Article 100409"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144632555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Oral and Maxillofacial Surgery Cases
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