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Intensive Diabetes Therapy Reduces Risk of Impaired GFR in DCCT/EDIC Studies DCCT/EDIC研究中强化糖尿病治疗降低GFR受损风险
Pub Date : 2011-12-01 DOI: 10.1097/01.NEP.0000411040.94909.38
M. Coleman
PHILADELPHIA—The long-term risk of an impaired glomerular fi ltration rate (GFR) was 50% lower among patients with type 1 diabetes who were treated early with intensive diabetes therapy compared with those treated with conventional diabetes therapy, according to two interrelated studies reported simultaneously here at the late-breaking clinical trials session of the American Society of Nephrology Kidney Week 2011 (LB-OR05) and as an online-fi rst publication in the New England Journal of Medicine. “This study provides the fi rst direct evidence that intensive glycemic control can prevent loss of GFR in type 1 diabetes,” said Joachim Ix, MD, MAS, of the Division of Nephrology–Hypertension at the University of California, San Diego. “This is remarkable, as before now, no prior study of any intervention has proven to prevent loss of GFR in type 1 diabetes.” The Diabetes Control and Complications Trial (DCCT) was designed as a multicenter clinical trial of patients with type 1 diabetes mellitus, enrolling a total of 1,441 participants • ASN KIDNEY WEEK •
早期接受强化糖尿病治疗的1型糖尿病患者肾小球滤过率(GFR)受损的长期风险比接受常规糖尿病治疗的患者低50%。根据2011年美国肾脏病学会肾脏周(LB-OR05)最新的临床试验会议和新英格兰医学杂志在线首次发表的两项相关研究。“这项研究提供了第一个直接证据,表明强化血糖控制可以预防1型糖尿病患者GFR的损失,”加州大学圣地亚哥分校肾病学-高血压科的医学博士Joachim Ix说。“这是值得注意的,因为在此之前,没有任何干预研究证明可以预防1型糖尿病患者的GFR损失。”糖尿病控制和并发症试验(DCCT)是一项针对1型糖尿病患者的多中心临床试验,共纳入1441名参与者
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引用次数: 0
Hypertension: Where Are We Now? 高血压:我们现在在哪里?
Pub Date : 2011-11-01 DOI: 10.1097/01.NEP.0000409973.92982.75
V. Bansal
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引用次数: 1
A Combined Specialty Clinic Offers Comparable Care at Lower Costs, Study Reports 联合专科诊所以较低的成本提供可比的护理,研究报告
Pub Date : 2011-11-01 DOI: 10.1097/01.NEP.0000409977.15854.1D
M. Coleman
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引用次数: 0
Blood Pressure Goals in CKD: Where Are We Going, and How Do We Get There? 慢性肾病的血压目标:我们要去哪里,我们如何达到目标?
Pub Date : 2011-11-01 DOI: 10.1097/01.NEP.0000409976.77735.df
R. Lafayette
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引用次数: 0
Estimated GFR As ‘Good’ as Gold Standard in CRIC Subset 估计GFR在CRIC子集中为“良好”金标准
Pub Date : 2011-10-01 DOI: 10.1097/01.nep.0000407883.56110.d2
F. Lowry
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引用次数: 0
Time to Talk About End-of-Life Care 是时候谈谈临终关怀了
Pub Date : 2011-10-01 DOI: 10.1097/01.NEP.0000407881.71357.35
A. Moss
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引用次数: 1
Proposed Donor-Derived Infection Guideline Has Transplant Community Speaking Out 拟议的供体来源感染指南引起了移植社区的关注
Pub Date : 2011-10-01 DOI: 10.1097/01.NEP.0000407879.63733.F2
M. Hogan
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引用次数: 0
The Potential for Graft First in Selected Patients 首先在选定患者中移植的潜力
Pub Date : 2011-09-01 DOI: 10.1097/01.NEP.0000406709.12001.7F
M. Allon
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引用次数: 0
Early Hematuria Associated with Increased ESRD Risk, but Rates Are Low 早期血尿与ESRD风险增加相关,但发生率较低
Pub Date : 2011-09-01 DOI: 10.1097/01.NEP.0000406711.19624.68
B. Roehr
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引用次数: 0
Acute Kidney Injury: We Must Do Better 急性肾损伤:我们必须做得更好
Pub Date : 2011-09-01 DOI: 10.1097/01.NEP.0000406710.12001.A9
R. Lafayette
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引用次数: 0
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Nephrology Times
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