{"title":"Changing Trends of Subacute Sclerosing Panencephalitis— Pre- and Postvaccination Era, Why Should Children Vaccinated against Measles Develop SSPE?","authors":"E. Agarwal, S. K, Rajadhyaksha S.","doi":"10.1055/S-0039-1694867","DOIUrl":"https://doi.org/10.1055/S-0039-1694867","url":null,"abstract":"","PeriodicalId":38086,"journal":{"name":"International Journal of Epilepsy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/S-0039-1694867","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45642462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
questionnaire. A video electroenceph-alography and CT brain (MRI in focal seizures) was done in all patients. of In focal in
问卷调查所有患者均进行了视频脑电图和脑CT（局灶性癫痫的MRI）检查。的In focus In
{"title":"Clinical Profile and Health-Related Quality of Life in Patients with Alcohol-Related Seizures","authors":"S. Prasanth, C. Shaji, Jithin Raj, Muhammad","doi":"10.1055/s-0039-1694885","DOIUrl":"https://doi.org/10.1055/s-0039-1694885","url":null,"abstract":"questionnaire. A video electroenceph-alography and CT brain (MRI in focal seizures) was done in all patients. of In focal in","PeriodicalId":38086,"journal":{"name":"International Journal of Epilepsy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/s-0039-1694885","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42834316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Kamel, S. Mounir, N. Okaily, M. Abdelzaher, Mohammed H. Hassan
Abstract Background There has been a long interest in investigating the relationship between heat shock protein (HSP) expression and the evidence of neuronal damage in the most susceptible brain areas after seizures. So, the present study aimed to assess heat shock protein (HSP70) in children with seizures (febrile seizures and epilepsy), and to find out the cutoff point of this marker that may help in confirming epilepsy diagnosis. The present study has been conducted to evaluate serum levels of HSP70 in children with epileptic and febrile seizures and to compare these results to that of healthy children. Materials and Methods A prospective study included 85 children (32 females and 53 males) in Children and Maternity Unit, Minia University Hospital, Minia, Egypt. Children were subdivided into three groups, group (I) included 30 children with epilepsy, group (II) included 30 children with febrile seizures, and group (III) included 25 healthy children that served as a control group. HSP70 assay was performed for all included children using the enzyme-linked immunosorbent assay technique. Results The overall results revealed significant high serum HSP70 levels in epilepsy and febrile seizures groups when compared with control group (p < 0.001). Also, HSP70 serum levels were significantly higher in epilepsy group than in febrile seizures group (p < 0.001). Serum HSP70 level at a cutoff point > 170 ng/L showed 60% sensitivity and specificity equal to 83.3% in prediction of epilepsy. Conclusion HSP70 level was significantly higher in epileptic and febrile seizures children than normal healthy children, and HSP70 may be beneficial in confirming the diagnosis of epilepsy.
{"title":"Possible Role of Heat Shock Protein 70 in Childhood Seizures","authors":"M. Kamel, S. Mounir, N. Okaily, M. Abdelzaher, Mohammed H. Hassan","doi":"10.1055/s-0038-1676907","DOIUrl":"https://doi.org/10.1055/s-0038-1676907","url":null,"abstract":"Abstract Background There has been a long interest in investigating the relationship between heat shock protein (HSP) expression and the evidence of neuronal damage in the most susceptible brain areas after seizures. So, the present study aimed to assess heat shock protein (HSP70) in children with seizures (febrile seizures and epilepsy), and to find out the cutoff point of this marker that may help in confirming epilepsy diagnosis. The present study has been conducted to evaluate serum levels of HSP70 in children with epileptic and febrile seizures and to compare these results to that of healthy children. Materials and Methods A prospective study included 85 children (32 females and 53 males) in Children and Maternity Unit, Minia University Hospital, Minia, Egypt. Children were subdivided into three groups, group (I) included 30 children with epilepsy, group (II) included 30 children with febrile seizures, and group (III) included 25 healthy children that served as a control group. HSP70 assay was performed for all included children using the enzyme-linked immunosorbent assay technique. Results The overall results revealed significant high serum HSP70 levels in epilepsy and febrile seizures groups when compared with control group (p < 0.001). Also, HSP70 serum levels were significantly higher in epilepsy group than in febrile seizures group (p < 0.001). Serum HSP70 level at a cutoff point > 170 ng/L showed 60% sensitivity and specificity equal to 83.3% in prediction of epilepsy. Conclusion HSP70 level was significantly higher in epileptic and febrile seizures children than normal healthy children, and HSP70 may be beneficial in confirming the diagnosis of epilepsy.","PeriodicalId":38086,"journal":{"name":"International Journal of Epilepsy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/s-0038-1676907","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44758691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bilateral Rassmussen's Encephalitis: A Rare and Difficult Entity—Case Report","authors":"Swapan Gupta, N. Chaudhry, V. Puri","doi":"10.1055/S-0039-1694901","DOIUrl":"https://doi.org/10.1055/S-0039-1694901","url":null,"abstract":"","PeriodicalId":38086,"journal":{"name":"International Journal of Epilepsy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/S-0039-1694901","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43080606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Perception of Epilepsy Stigma in School Children and Teachers’ Awareness and Attitude towards Epilepsy—A South Indian Cohort Study","authors":"G. Goud, V. Chinta, R. Mrudula, R. Borgohain","doi":"10.1055/S-0039-1694870","DOIUrl":"https://doi.org/10.1055/S-0039-1694870","url":null,"abstract":"","PeriodicalId":38086,"journal":{"name":"International Journal of Epilepsy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/S-0039-1694870","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42922375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Third Generation Cardioselective Beta Blocker Exhibits Significant Anticonvulsant Properties in Pentylenetetrazole Model in Wistar Albino Rats","authors":"C. D., Karamthoti B., Kurra B.","doi":"10.1055/s-0039-1694863","DOIUrl":"https://doi.org/10.1055/s-0039-1694863","url":null,"abstract":"","PeriodicalId":38086,"journal":{"name":"International Journal of Epilepsy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/s-0039-1694863","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43397528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Sethi, P. Carney, Laura K. Zugno, J. Archer, G. Jackson
{"title":"“Super-Focal” Cortical Resection in MRI-Negative Epilepsy using Multimodal Imaging-Guided Stereo EEG: A Case Report","authors":"M. Sethi, P. Carney, Laura K. Zugno, J. Archer, G. Jackson","doi":"10.1055/S-0039-1694884","DOIUrl":"https://doi.org/10.1055/S-0039-1694884","url":null,"abstract":"","PeriodicalId":38086,"journal":{"name":"International Journal of Epilepsy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/S-0039-1694884","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46875287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Archita Chawla, R. Bansal, S. Sharma, N. Bansal, Gagandeep Singh, Ch C Gupta, Karan Chouhan
{"title":"An Ethnographic and Structured Assessment of Treatment-Seeking Attitudes and Behaviors of People with Epilepsy in the Community","authors":"Archita Chawla, R. Bansal, S. Sharma, N. Bansal, Gagandeep Singh, Ch C Gupta, Karan Chouhan","doi":"10.1055/S-0039-1694860","DOIUrl":"https://doi.org/10.1055/S-0039-1694860","url":null,"abstract":"","PeriodicalId":38086,"journal":{"name":"International Journal of Epilepsy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/S-0039-1694860","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46907857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rakesh Mishra, N. Mariyappa, S. Sinha, A. Arivazhagan, M. Rao
{"title":"Magnetic Source Imaging of Eloquent Cortex: Novel Findings and Implications","authors":"Rakesh Mishra, N. Mariyappa, S. Sinha, A. Arivazhagan, M. Rao","doi":"10.1055/S-0039-1694889","DOIUrl":"https://doi.org/10.1055/S-0039-1694889","url":null,"abstract":"","PeriodicalId":38086,"journal":{"name":"International Journal of Epilepsy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/S-0039-1694889","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48243667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Focal-onset seizures can be caused by underlying brain lesions including focal lesions such as granulomas, low-grade neoplasms, vascular lesions, or neuronal migration disorders. Polymicrogyria is a congenital abnormality of cortical formation occurring during embryonic life. Choroidal fissure cysts are either arachnoid or neuroepithelial cysts arising at the choroidal fissure, and mostly they are incidental findings having no significant clinical implications. Coexistence of both of these can lead to dilemma in the management decisions. We present a case of focal-onset seizures with an unreported coexistence of polymicrogyria with choroidal fissure cyst.
{"title":"Coexistence of Temporo-Occipital Polymicrogyria with Choroidal Fissure Cyst in a Case of Focal Onset Seizures","authors":"M. Kiran, A. Karthik, L. Lekshmi., K. Nagarajan","doi":"10.1055/s-0039-1683836","DOIUrl":"https://doi.org/10.1055/s-0039-1683836","url":null,"abstract":"Abstract Focal-onset seizures can be caused by underlying brain lesions including focal lesions such as granulomas, low-grade neoplasms, vascular lesions, or neuronal migration disorders. Polymicrogyria is a congenital abnormality of cortical formation occurring during embryonic life. Choroidal fissure cysts are either arachnoid or neuroepithelial cysts arising at the choroidal fissure, and mostly they are incidental findings having no significant clinical implications. Coexistence of both of these can lead to dilemma in the management decisions. We present a case of focal-onset seizures with an unreported coexistence of polymicrogyria with choroidal fissure cyst.","PeriodicalId":38086,"journal":{"name":"International Journal of Epilepsy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/s-0039-1683836","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43383396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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