Pub Date : 2025-12-06DOI: 10.1016/j.jcpo.2025.100675
Tianjiao Gao , Marwa Farag , Sohail Agha , Linda Mobula , Xiaohui Hou , Guohong Li , Wu Zeng
Background
This study retrospectively examines the cost-effectiveness of the national HPV vaccination program using the program cost and coverage data in Nigeria.
Methods
We conducted a cost-effectiveness analysis of the HPV vaccination program compared with no vaccination in Nigeria, adopting both health system and societal perspectives. A static Markov model simulating HPV infection and cervical cancer outcomes was developed for a cohort of girls aged 9–14 years, followed until age 100. The model comprised primarily the following health states: susceptible, cervical cancer, and death. It further incorporated three additional pathways for patients with cervical cancer, including those with successful treatment, with treatment failure, and with no treatment.
Results
The incremental cost-effectiveness ratio (ICER) was estimated at $268.67 per quality-adjusted life year (QALY) gained from the health system perspective and $217.85 per QALY gained from the societal perspective. Both ICERs were well below the cost-effectiveness threshold of one-time GDP per capita in Nigeria ($806.95). Key drivers of cost-effectiveness included vaccine cost, treatment success rate, cervical cancer treatment coverage, and cervical cancer utility values.
Discussion
The single-dose HPV vaccination program is highly cost-effective in Nigeria, compared to the status quo of no vaccination. To ensure long-term sustainability, the Nigerian government should strengthen financing mechanisms and the healthcare system to support the program.
Policy Summary
Single dose HPV vaccination is cost-effective in Nigeria. It is crucial to obtain sustainable vaccine financing and improve treatment to maintain the program impact.
{"title":"Economic evaluation of the one-dose HPV vaccination program in Nigeria","authors":"Tianjiao Gao , Marwa Farag , Sohail Agha , Linda Mobula , Xiaohui Hou , Guohong Li , Wu Zeng","doi":"10.1016/j.jcpo.2025.100675","DOIUrl":"10.1016/j.jcpo.2025.100675","url":null,"abstract":"<div><h3>Background</h3><div>This study retrospectively examines the cost-effectiveness of the national HPV vaccination program using the program cost and coverage data in Nigeria.</div></div><div><h3>Methods</h3><div>We conducted a cost-effectiveness analysis of the HPV vaccination program compared with no vaccination in Nigeria, adopting both health system and societal perspectives. A static Markov model simulating HPV infection and cervical cancer outcomes was developed for a cohort of girls aged 9–14 years, followed until age 100. The model comprised primarily the following health states: susceptible, cervical cancer, and death. It further incorporated three additional pathways for patients with cervical cancer, including those with successful treatment, with treatment failure, and with no treatment.</div></div><div><h3>Results</h3><div>The incremental cost-effectiveness ratio (ICER) was estimated at $268.67 per quality-adjusted life year (QALY) gained from the health system perspective and $217.85 per QALY gained from the societal perspective. Both ICERs were well below the cost-effectiveness threshold of one-time GDP per capita in Nigeria ($806.95). Key drivers of cost-effectiveness included vaccine cost, treatment success rate, cervical cancer treatment coverage, and cervical cancer utility values.</div></div><div><h3>Discussion</h3><div>The single-dose HPV vaccination program is highly cost-effective in Nigeria, compared to the status quo of no vaccination. To ensure long-term sustainability, the Nigerian government should strengthen financing mechanisms and the healthcare system to support the program.</div></div><div><h3>Policy Summary</h3><div>Single dose HPV vaccination is cost-effective in Nigeria. It is crucial to obtain sustainable vaccine financing and improve treatment to maintain the program impact.</div></div>","PeriodicalId":38212,"journal":{"name":"Journal of Cancer Policy","volume":"47 ","pages":"Article 100675"},"PeriodicalIF":2.0,"publicationDate":"2025-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145709939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bhutan has achieved 90–70–90 global targets by 2023, way ahead of the global targets of elimination of cervical cancer by 2030. However, cervical cancer remains the most prevalent cancer, among women in Bhutan. While all healthcare screening, diagnosis and treatment of cervical cancers are provided free of cost, sustainability in terms of financing and human resources and ensuring quality of services are the major challenges. Development of a national standard guideline is a major intervention towards improving the quality of colposcopy services and treatment of precancer in the country. In this article, we discuss the summary of the consensus-based practical guideline on colposcopy and treatment of cervical pre-cancers in Bhutan, challenges faced and potential way forward.
{"title":"Quality improvement initiatives on colposcopy and treatment of cervical pre-cancer services in Bhutan: Experiences, challenges, and way forward","authors":"Namkha Dorji, Thinley Dorji, Yeshey Dorjey, Yangdon Yangdon","doi":"10.1016/j.jcpo.2025.100676","DOIUrl":"10.1016/j.jcpo.2025.100676","url":null,"abstract":"<div><div>Bhutan has achieved 90–70–90 global targets by 2023, way ahead of the global targets of elimination of cervical cancer by 2030. However, cervical cancer remains the most prevalent cancer, among women in Bhutan. While all healthcare screening, diagnosis and treatment of cervical cancers are provided free of cost, sustainability in terms of financing and human resources and ensuring quality of services are the major challenges. Development of a national standard guideline is a major intervention towards improving the quality of colposcopy services and treatment of precancer in the country. In this article, we discuss the summary of the consensus-based practical guideline on colposcopy and treatment of cervical pre-cancers in Bhutan, challenges faced and potential way forward.</div></div>","PeriodicalId":38212,"journal":{"name":"Journal of Cancer Policy","volume":"47 ","pages":"Article 100676"},"PeriodicalIF":2.0,"publicationDate":"2025-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145685016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-04DOI: 10.1016/j.jcpo.2025.100673
Red Thaddeus D. Miguel, Isabella Steffensen
{"title":"Evidence on vaping e-cigarettes as a risk factor for cancer: A cautionary tale in flawed synthesis","authors":"Red Thaddeus D. Miguel, Isabella Steffensen","doi":"10.1016/j.jcpo.2025.100673","DOIUrl":"10.1016/j.jcpo.2025.100673","url":null,"abstract":"","PeriodicalId":38212,"journal":{"name":"Journal of Cancer Policy","volume":"47 ","pages":"Article 100673"},"PeriodicalIF":2.0,"publicationDate":"2025-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145696375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01DOI: 10.1016/j.jcpo.2025.100670
Linsey Eldridge, Amina Chtourou, Kalina Duncan, Leslie Given, Sana Haider, Karin Hohman, Douglas M Puricelli Perin, Yannick Romero, Zuzanna Tittenbrun, Mishka Kohli Cira
Background: As cancer incidence in low- and middle-income countries (LMICs) continues to rise, the development of National Cancer Control Plans (NCCP) has become an essential policy tool for guiding a comprehensive and coordinated response. The NCCP Development Research Initiative (NCCP DRIVE) is a qualitative study led by the International Cancer Control Partnership (ICCP) to understand the NCCP development process and contextual factors that may enable or impede effective NCCP development.
Methods: In-depth interviews were conducted with country-level cancer planners in nine countries (seven African, two South Asian) within the ICCP network. Transcripts were recorded, transcribed, and double-coded in Dedoose, then analyzed thematically using the Health Policy Triangle (HPT) framework.
Results: Findings highlight that NCCP development is dynamic and iterative, following six commonly reported phases: Initiation, Formulation, Negotiation, Communication, Implementation, and Monitoring/Evaluation. Common challenges reported by respondents included limited financial and human resources, competing priorities, fragmented health systems, and inadequate data. These constraints led to compressed timelines, overlapping planning activities, and gaps in costing and implementation plans. To address these challenges, respondents employed various strategies, including integrating cancer control efforts with existing health programs, engaging multisector actors, building political will, and securing technical assistance (TA) from partners. Building partnerships was pivotal, helping to set priorities, align plans with national and global agendas, and leverage resources. However, some respondents reported misaligned timelines and priorities, and coordination challenges.
Conclusion: This study contributes a policy framework-informed, implementation-focused analysis of NCCP development, offering practical insights into how countries navigate complex challenges to initiate and sustain cancer control planning. Findings underscore the need for flexible TA models and stronger data systems, and the value of integrating cancer control priorities within existing health systems. Understanding these dynamics from initiation to implementation offers practical insights for countries at various stages of development, and for partners providing technical assistance.
{"title":"Understanding the development process of national cancer control plans in low- and middle-income countries.","authors":"Linsey Eldridge, Amina Chtourou, Kalina Duncan, Leslie Given, Sana Haider, Karin Hohman, Douglas M Puricelli Perin, Yannick Romero, Zuzanna Tittenbrun, Mishka Kohli Cira","doi":"10.1016/j.jcpo.2025.100670","DOIUrl":"https://doi.org/10.1016/j.jcpo.2025.100670","url":null,"abstract":"<p><strong>Background: </strong>As cancer incidence in low- and middle-income countries (LMICs) continues to rise, the development of National Cancer Control Plans (NCCP) has become an essential policy tool for guiding a comprehensive and coordinated response. The NCCP Development Research Initiative (NCCP DRIVE) is a qualitative study led by the International Cancer Control Partnership (ICCP) to understand the NCCP development process and contextual factors that may enable or impede effective NCCP development.</p><p><strong>Methods: </strong>In-depth interviews were conducted with country-level cancer planners in nine countries (seven African, two South Asian) within the ICCP network. Transcripts were recorded, transcribed, and double-coded in Dedoose, then analyzed thematically using the Health Policy Triangle (HPT) framework.</p><p><strong>Results: </strong>Findings highlight that NCCP development is dynamic and iterative, following six commonly reported phases: Initiation, Formulation, Negotiation, Communication, Implementation, and Monitoring/Evaluation. Common challenges reported by respondents included limited financial and human resources, competing priorities, fragmented health systems, and inadequate data. These constraints led to compressed timelines, overlapping planning activities, and gaps in costing and implementation plans. To address these challenges, respondents employed various strategies, including integrating cancer control efforts with existing health programs, engaging multisector actors, building political will, and securing technical assistance (TA) from partners. Building partnerships was pivotal, helping to set priorities, align plans with national and global agendas, and leverage resources. However, some respondents reported misaligned timelines and priorities, and coordination challenges.</p><p><strong>Conclusion: </strong>This study contributes a policy framework-informed, implementation-focused analysis of NCCP development, offering practical insights into how countries navigate complex challenges to initiate and sustain cancer control planning. Findings underscore the need for flexible TA models and stronger data systems, and the value of integrating cancer control priorities within existing health systems. Understanding these dynamics from initiation to implementation offers practical insights for countries at various stages of development, and for partners providing technical assistance.</p>","PeriodicalId":38212,"journal":{"name":"Journal of Cancer Policy","volume":" ","pages":"100670"},"PeriodicalIF":2.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145670139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01DOI: 10.1016/j.jcpo.2025.100639
Linsey Eldridge, Kalina Duncan, Mishka Kohli Cira
{"title":"Response to ‘beyond virtual learning: Leveraging project ECHO to sustain and localize national cancer control plan implementation in LMICs’","authors":"Linsey Eldridge, Kalina Duncan, Mishka Kohli Cira","doi":"10.1016/j.jcpo.2025.100639","DOIUrl":"10.1016/j.jcpo.2025.100639","url":null,"abstract":"","PeriodicalId":38212,"journal":{"name":"Journal of Cancer Policy","volume":"46 ","pages":"Article 100639"},"PeriodicalIF":2.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145070951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01DOI: 10.1016/j.jcpo.2025.100667
Yasmin Jahan , Atiqur SM-Rahman
{"title":"Corrigendum to “Bridging the equity gap in colorectal cancer screening: A comparative analysis across high-income countries” [J. Cancer Policy 46 (2025) 100657]","authors":"Yasmin Jahan , Atiqur SM-Rahman","doi":"10.1016/j.jcpo.2025.100667","DOIUrl":"10.1016/j.jcpo.2025.100667","url":null,"abstract":"","PeriodicalId":38212,"journal":{"name":"Journal of Cancer Policy","volume":"46 ","pages":"Article 100667"},"PeriodicalIF":2.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145524506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01DOI: 10.1016/j.jcpo.2025.100637
Ajay Aggarwal, Richard Sullivan
{"title":"Mapping the global oncology & policy research landscape","authors":"Ajay Aggarwal, Richard Sullivan","doi":"10.1016/j.jcpo.2025.100637","DOIUrl":"10.1016/j.jcpo.2025.100637","url":null,"abstract":"","PeriodicalId":38212,"journal":{"name":"Journal of Cancer Policy","volume":"46 ","pages":"Article 100637"},"PeriodicalIF":2.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144972800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Project ECHO has emerged as a promising virtual peer-learning model to support National Cancer Control Plan (NCCP) implementation in low- and middle-income countries (LMICs). It aligns with the WHO Global Action Plan for the Prevention and Control of Noncommunicable Diseases 2013–2020, which underscores national coordination and multisectoral action [2]. In response to the recent evaluation by Eldridge et al., we offer additional insights highlighting the limitations of individual-level training when structural barriers remain unaddressed. Drawing lessons from cervical cancer prevention in Botswana and palliative care capacity-building in India, we argue that ECHO’s full potential lies in national-level integration, cross-sector policy coordination, and localized implementation. This correspondence emphasizes a systems-level perspective to sustainably embed ECHO-based knowledge into cancer control programs across LMICs.
{"title":"Beyond virtual learning: Leveraging project ECHO to sustain and localize national cancer control plan implementation in LMICs","authors":"Nathkapach Kaewpitoon Rattanapitoon, Natnapa Heebkaew Padchasuwan, Nav La, Schawanya Kaewpitoon Rattanapitoon","doi":"10.1016/j.jcpo.2025.100638","DOIUrl":"10.1016/j.jcpo.2025.100638","url":null,"abstract":"<div><div>Project ECHO has emerged as a promising virtual peer-learning model to support National Cancer Control Plan (NCCP) implementation in low- and middle-income countries (LMICs). It aligns with the WHO Global Action Plan for the Prevention and Control of Noncommunicable Diseases 2013–2020, which underscores national coordination and multisectoral action [2]. In response to the recent evaluation by Eldridge et al., we offer additional insights highlighting the limitations of individual-level training when structural barriers remain unaddressed. Drawing lessons from cervical cancer prevention in Botswana and palliative care capacity-building in India, we argue that ECHO’s full potential lies in national-level integration, cross-sector policy coordination, and localized implementation. This correspondence emphasizes a systems-level perspective to sustainably embed ECHO-based knowledge into cancer control programs across LMICs.</div></div>","PeriodicalId":38212,"journal":{"name":"Journal of Cancer Policy","volume":"46 ","pages":"Article 100638"},"PeriodicalIF":2.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145070990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-29DOI: 10.1016/j.jcpo.2025.100671
Truong Ngoc Tham , Nguyen Le My Han , Nguyen Thien Quang , Bui Dan Hieu Phuong , Nguyen Thao Ngan , Phillip Tran , Nguyen Tien Huy
{"title":"Cancer is getting younger: Alarming patterns of early-onset malignancies in Vietnam","authors":"Truong Ngoc Tham , Nguyen Le My Han , Nguyen Thien Quang , Bui Dan Hieu Phuong , Nguyen Thao Ngan , Phillip Tran , Nguyen Tien Huy","doi":"10.1016/j.jcpo.2025.100671","DOIUrl":"10.1016/j.jcpo.2025.100671","url":null,"abstract":"","PeriodicalId":38212,"journal":{"name":"Journal of Cancer Policy","volume":"47 ","pages":"Article 100671"},"PeriodicalIF":2.0,"publicationDate":"2025-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145655757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}