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Delayed diagnosis of parkinsonism hyperpyrexia syndrome resulting in death: a case report 帕金森病高热综合征的延误诊断导致死亡1例
Q4 Medicine Pub Date : 2022-07-15 DOI: 10.12809/ajgg-2021-497-cr
C. Kwok, Y. Chan
A 68-year-old woman with a history of Parkinson disease was admitted for Escherichia coli urinary tract infection and physical deconditioning. She was subsequently found to have a history of rheumatoid arthritis and iatrogenic Cushing syndrome with adrenal insufficiency. The patient developed high fever, fluctuating blood pressure, hypertonia, progressive confusion, and recurrent generalised tonic-clonic seizures. She was kept nil by mouth, and levodopa was withheld for 2 days. Blood test showed elevated creatine kinase level. Diagnosis of parkinsonism hyperpyrexia syndrome was made after consultation with neurologists, and levodopa was resumed. However, her condition did not improve and she later died. This case highlights the precipitating factors of parkinsonism hyperpyrexia syndrome and the importance of early recognition of the disease. Care must be taken in avoiding sudden withdrawal of levodopa in patients with Parkinson disease.
一名68岁女性,有帕金森病病史,因大肠杆菌尿路感染和身体不适入院。随后发现她有类风湿关节炎和医源性库欣综合征伴肾上腺功能不全病史。患者出现高热、血压波动、高张力、进行性意识不清和复发性全身性强直阵挛发作。口服0,停服左旋多巴2天。血液检查显示肌酸激酶水平升高。与神经科医生会诊后诊断为帕金森性高热综合征,并恢复左旋多巴治疗。然而,她的病情没有好转,后来去世了。本病例强调了帕金森病高热综合征的诱发因素和早期识别疾病的重要性。帕金森病患者必须注意避免左旋多巴突然停药。
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引用次数: 0
Calciphylaxis of the fingers: a case report 手指钙化反应1例报告
Q4 Medicine Pub Date : 2022-07-15 DOI: 10.12809/ajgg-2021-501-cr
Zay Yar Aung, Kumar Sheetanshu, Shan‐Xian Lee, C. Chen
We report a case of calciphylaxis of the fingers in a 75-year-old woman with end-stage renal disease. She was on haemodialysis and had diabetes mellitus, hypertension, ischaemic heart disease, and hypothyroidism. She presented with progressive blackish discoloration of the fingertips of both hands. Calciphylaxis is caused by arterial calcification with consequent tissue necrosis and gangrene. It commonly occurs in patients with chronic kidney disease undergoing haemodialysis. Treatment involves modifying risk factors, wound care, cinacalcet, and sodium thiosulfate in addition to haemodialysis.
我们报告一位75岁末期肾脏疾病女性的手指钙化反应病例。她正在接受血液透析,患有糖尿病、高血压、缺血性心脏病和甲状腺功能减退症。她的双手指尖出现逐渐变黑的变色。钙化反应是由动脉钙化引起的,并伴随着组织坏死和坏疽。它通常发生在接受血液透析的慢性肾脏疾病患者中。治疗包括改变危险因素、伤口护理、西那卡司和硫代硫酸钠,以及血液透析。
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引用次数: 0
Pain and frailty among community-dwelling older people in Hong Kong 香港社区长者的痛苦和虚弱
Q4 Medicine Pub Date : 2022-07-15 DOI: 10.12809/ajgg-2022-529-oa
Doris KY Miu
Introduction. Pain and frailty are common geriatric syndromes and can lead to adverse health outcomes. This study aims to examine the association between pain and frailty in community-dwelling older adults in Hong Kong and to suggest a patient-centred intervention for frail older people with pain. Methods: Community-dwelling older adults aged ≥ 65 years were invited to attend a health check programme. Characteristics of pain were recorded, including the presence of pain, the total number of pain sites, the highest pain intensity, and the frequency of pain. The 5-item FRAIL scale was used to screen frailty. The Lawton instrumental activity of daily living (IADL) scale was used to assess independence. Handgrip strength of the dominant hand and walking speed for 6 meters were measured. Results: Of 445 older adults who attended the health check programme, 265 women and 64 men (mean age, 75 years) agreed to participate and were included for analysis. Of them, 123 (37.4%) reported persistent pain, 116 (35.5%) reported sporadic pain, and 90 (27.4%) reported no pain. Participants were classified as frail (n=47, 14.3%), prefrail (n=200, 60.8%), or robust (n=82, 24.9%). Comparing the combined frail and prefrail group with the robust group, frailty was independently associated with age (odds ratios [OR]=1.053, p=0.007), Lawton IADL (OR=0.602, p=0.004), and sporadic pain (OR=2.072, p=0.031), after adjusting for walking speed and handgrip strength. Conclusion: The prevalence of frailty is high among community-dwelling older adults in Hong Kong. Age, IADL, and sporadic pain are independently associated with frailty; only pain is amenable. Pain management may help prevent progression to frailty in older people.
介绍疼痛和虚弱是常见的老年综合征,可导致不良的健康后果。本研究旨在研究香港社区老年人疼痛与虚弱之间的关系,并建议对患有疼痛的虚弱老年人进行以患者为中心的干预。方法:邀请年龄≥65岁的社区老年人参加健康检查项目。记录疼痛特征,包括疼痛的存在、疼痛部位的总数、最高疼痛强度和疼痛频率。采用5项脆弱性量表进行脆弱性筛查。劳顿工具性日常生活活动量表用于评估独立性。测量了优势手的握力和6米的步行速度。结果:在445名参加健康检查计划的老年人中,265名女性和64名男性(平均年龄75岁)同意参加并被纳入分析。其中,123人(37.4%)报告持续疼痛,116人(35.5%)报告偶发疼痛,90人(27.4%)报告无疼痛。参与者被分为虚弱(n=47,14.3%)、运动前(n=200,60.8%)或强健(n=82,24.9%)。将虚弱和运动前组合组与强健组进行比较,在调整了步行速度和握力后,虚弱与年龄(比值比[or]=1.053,p=0.007)、劳顿IADL(or=0.602,p=0.004)和偶发疼痛(or=2.072,p=0.031)独立相关。结论:香港社区老年人虚弱患病率较高。年龄、IADL和散发性疼痛与虚弱独立相关;只有疼痛是可以忍受的。疼痛管理可能有助于防止老年人发展为虚弱。
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引用次数: 0
Simulation training on donning personal protective equipment and performing cardiopulmonary resuscitation for nurses in a geriatric step-down hospital during COVID-19 新冠肺炎期间老年降压医院护士穿戴个人防护装备和心肺复苏的模拟训练
Q4 Medicine Pub Date : 2022-07-15 DOI: 10.12809/ajgg-2021-460-oa
T. Chan, Frankie KK Lam, Hoi-Yan Lam, So Law, Pui-Lui Cheung, YC Tsang, A. Chan, F. H. Chan, J. Luk
Background. Donning personal protective equipment (PPE) and performing cardiopulmonary resuscitation (CPR) are stressful tasks for healthcare professionals, particularly during the COVID-19 pandemic. This study aimed to assess the effectiveness of simulation training on donning PPE and performing CPR with PPE put on for nurses at a geriatric step-down hospital. Methods. A lecture and simulation training on donning PPE and performing CPR were provided for nurses. Confidence in donning PPE and performing CPR, knowledge of CPR, and satisfaction of participants were assessed before training (baseline), after the lecture, and after the simulation training. Results. 50 nurses (33 women and 17 men) attended both the lecture and simulation training, accounting for 90% of nurses in the department. Self-rated confidence in donning PPE and performing CPR improved significantly after the lecture (both p<0.001) and again after the simulation training (both p<0.001). Knowledge of CPR improved significantly after the lecture (p<0.001). Self-rated satisfaction of participants was high (9.3±0.3). Conclusion. Simulation training on donning PPE and performing CPR with PPE put on significantly improves the knowledge and confidence of nurses in a geriatric step-down hospital. This may contribute to improved patient outcomes, particularly during the COVID-19 pandemic. © 2022 The Hong Kong Geriatrics Society and Hong Kong Association of Gerontology.
背景穿戴个人防护装备(PPE)和进行心肺复苏术(CPR)对医护人员来说是压力很大的任务,尤其是在新冠肺炎大流行期间。本研究旨在评估老年降压医院护士穿戴个人防护装备和使用个人防护装备进行心肺复苏的模拟培训的有效性。方法。为护士们提供了关于穿戴个人防护装备和进行心肺复苏的讲座和模拟培训。在训练前(基线)、讲座后和模拟训练后评估参与者对穿戴个人防护装备和进行心肺复苏的信心、心肺复苏知识和满意度。后果50名护士(33名女性和17名男性)参加了讲座和模拟培训,占科室护士的90%。讲座结束后,参与者对穿戴个人防护装备和进行心肺复苏术的自评信心显著提高(均<0.001),模拟训练结束后再次提高(均p<0.001)。心肺复苏知识在讲座结束后显著提高(p<0.001),参与者自评满意度高(9.3±0.3)。结论。穿戴个人防护装备和戴上个人防护装备进行心肺复苏的模拟培训显著提高了老年降压医院护士的知识和信心。这可能有助于改善患者的预后,特别是在新冠肺炎大流行期间。©2022香港老年医学会和香港老年病学协会。
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引用次数: 0
Video-based fall prevention education for cognitively impaired inpatients: a pilot study 基于视频的认知障碍住院患者跌倒预防教育:一项试点研究
Q4 Medicine Pub Date : 2022-07-15 DOI: 10.12809/ajgg-2021-490-oa
J. Dai, Sibgat Saleheen, Anita Ko, Ishrat Jahan, N. Braidy, D. Chan
Background. Inpatient falls complicate and lengthen hospital admissions for older adults. Cognitive impairment is a risk factor for falls. Current fall prevention education is ineffective for people with cognitive impairment. We aimed to investigate whether an educational video is a better mode of delivery than verbal education for individuals with cognitive impairment in terms of recall and fall prevention. Methods: In a randomised controlled trial, patients were assigned at random to receive fall prevention education either verbally or through an educational video. The co-primary outcomes were recall at 1 day and number of falls. Results: Of 21 and 31 participants assigned to receive video education (intervention) and verbal education (active comparator), respectively, 19 and 31 completed the study, respectively. The percentage of participants who recalled the fall prevention message was significantly higher in the intervention group than in the active comparator group (31.5% [6/19] vs 9.7% [3/31], p=0.03). There was no significant difference in the fall rate between groups. Conclusion: Fall prevention education delivered using a video may be better retained by individuals with cognitive impairment when compared with the standard practice of verbal fall prevention education. Larger studies are needed to confirm our findings.
背景住院病人跌倒使老年人的住院时间延长。认知障碍是跌倒的危险因素。目前的预防跌倒教育对有认知障碍的人来说是无效的。我们的目的是调查在回忆和跌倒预防方面,对于认知障碍患者来说,教育视频是否是比言语教育更好的传递方式。方法:在一项随机对照试验中,患者被随机分配接受口头或教育视频的跌倒预防教育。共同主要结果是第1天的回忆和跌倒次数。结果:在分别接受视频教育(干预)和言语教育(主动对照)的21名和31名参与者中,分别有19名和31人完成了研究。干预组参与者回忆起预防跌倒信息的百分比显著高于主动对照组(31.5%[6/19]vs 9.7%[3/31],p=0.03)。两组之间的跌倒率没有显著差异。结论:与言语预防跌倒教育的标准实践相比,认知障碍患者可以更好地保留使用视频进行的预防跌倒教育。需要更大规模的研究来证实我们的发现。
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引用次数: 0
Cognitive impairment and parkinsonism as a manifestation of delayed neuropsychological sequelae after carbon monoxide poisoning: a case report 一氧化碳中毒后迟发性神经心理后遗症表现为认知障碍和帕金森病1例
Q4 Medicine Pub Date : 2022-07-15 DOI: 10.12809/ajgg-2021-487-cr
Trishpal Kaur Dhaliwal, B. H. Rosario
We report a case of delayed neuropsychological sequelae manifesting as cognitive impairment and parkinsonism in a 72-year-old woman who attempted suicide by carbon monoxide poisoning 20 years earlier. was admitted after a fall-related traumatic brain injury resulting in bilateral sub-dural haemorrhages and seizures. She had hypertension, hyperlipidaemia, and depression. She had undergone mastectomy for right breast cancer 20 years earlier. She needed assistance in all instrumental activities of daily living (IADLs) and most basic ADLs. She had deficits in all six of the neurocognitive domains, with severe executive dysfunction, impaired language with paucity of spontaneous speech, and impaired memory and attention for 10 years. She was apathetic with low mood. Notably, in her early 50s, she had attempted suicide by CO poisoning and required mechanical ventilation for 10 days, after which her cognitive and functional deficits developed. Examination revealed features of parkinsonism with hypomimia, bilateral cogwheeling and lead-pipe rigidity of the upper limbs, generalised bradykinesia, and slow gait with decreased arm swing. Her abbreviated mental test score was 8/10. Her mini-mental state examination score was 22/30, with impairments in orientation and visuospatial tasks and unimpaired three-item recall. Her Geriatric Depression scale score was 11/15. She had vitamin B12 deficiency (<111 pmol/L) [normal range, 145-637 pmol/L) and was administered vitamin B12 replacement. Test results of and profiles, thyroid
我们报告了一例延迟性神经心理后遗症,表现为认知障碍和帕金森综合征,该患者是一名72岁的女性,20年前曾试图通过一氧化碳中毒自杀。在跌倒相关的创伤性脑损伤导致双侧硬膜下出血和癫痫发作后入院。她患有高血压、高脂血症和抑郁症。20年前,她因右乳腺癌症接受了乳房切除术。她在日常生活的所有工具性活动和最基本的日常生活能力方面都需要帮助。她在所有六个神经认知领域都有缺陷,严重的执行功能障碍,语言受损,缺乏自发语言,记忆力和注意力受损达10年之久。她情绪低落,无动于衷。值得注意的是,在她50岁出头的时候,她曾试图通过一氧化碳中毒自杀,并需要机械通气10天,之后她的认知和功能出现了缺陷。检查显示帕金森综合征的特征是模仿功能减退、双侧上肢转动和铅管僵硬、全身性运动迟缓和步态缓慢伴手臂摆动减少。她的简略心理测试成绩是8/10。她的迷你精神状态检查得分为22/30,在定向和视觉空间任务方面有障碍,三项回忆未受损。她的老年抑郁症量表评分为11/15。她患有维生素B12缺乏症(<111 pmol/L)[正常范围,145-637 pmol/L],并服用了维生素B12替代品
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引用次数: 0
Colourimetric capnometry to verify nasogastric tube placement in patients at risk of mal-placement 比色测量法验证有放置不正确风险的患者鼻胃管放置
Q4 Medicine Pub Date : 2021-12-17 DOI: 10.12809/ajgg-2020-446-oa
Peggy Pp Cheng, Iris FK Lee
Background. Nasogastric tubes (NGT) are frequently used in geriatric settings and verification of NGT placement is important for patient safety. This study aimed to ascertain the accuracy of carbon dioxide (CO2) colourimeter in the verification of NGT and to estimate the reduction in patient waiting time for resumption of NGT feeding in the general care setting. Methods. Doubtful NGT placements were obtained from patients in three medical extended wards in a public hospital in Hong Kong. Doubtful NGT placements were verified using both X-ray imaging and CO2 colourimeter. The sensitivity and specificity of CO2 colourimeter were evaluated using X-ray imaging as the gold standard. The patient waiting time for resumption of NGT feeding were estimated by recording the time required for completion of X-ray imaging verification. Results. There were 26 patients in the study with a mean age of 74.07 years (SD = 16.33). Fifteen (57.7%) of them were male. The final sample consisted of 71 doubtful NGT placement and none of them was misplaced. The specificity of CO2 colourimeter was 98.6%, while the sensitivity was unable to determine. The patient waiting time required for X-ray imaging verification ranged from 51 to 1095 minutes (mean = 380.75 min., SD = 179.51). Conclusions. CO2 colourimeter has high specificity in verification of doubtful NGT placement. Replacing X-ray imaging with CO2 colourimetry verification may speed up resumption of NGT feeding.
背景鼻导管(NGT)在老年患者中经常使用,NGT放置的验证对患者安全很重要。本研究旨在确定二氧化碳(CO2)色度计在NGT验证中的准确性,并估计在普通护理环境中患者等待恢复NGT喂养的时间减少。方法。香港一家公立医院的三个医疗扩展病房的患者接受了可疑的NGT安置。使用X射线成像和CO2色度计对可疑的NGT放置进行了验证。以X射线成像为金标准,评价CO2色度计的灵敏度和特异性。通过记录完成X射线成像验证所需的时间来估计患者等待恢复NGT喂养的时间。后果研究中有26名患者,平均年龄74.07岁(SD=16.33),其中15名(57.7%)为男性。最后的样本由71个可疑的NGT放置组成,没有一个放错地方。CO2色度计的特异性为98.6%,但灵敏度无法确定。X射线成像验证所需的患者等待时间为51-1095分钟(平均值=380.75分钟,标准差=179.51)。结论。CO2色度计在验证可疑NGT放置方面具有很高的特异性。用CO2比色法验证代替X射线成像可以加快NGT喂养的恢复。
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引用次数: 2
Editorial 社论
Q4 Medicine Pub Date : 2021-12-17 DOI: 10.12809/ajgg-v16n2-ed
J. Luk
Assessment and prevention of frailty and sarcopenia are of particular importance during the COVID-19 pandemic. Since 2020, the pandemic has been a new risk factor for frailty and sarcopenia. Feeding problems are common among older patients who had a stroke, advanced dementia, neurologic degenerative diseases (parkinsonism), or sarcopenic dysphagia.3 Although careful hand feeding is implemented in some geriatric units, nasogastric tube feeding is common in Hong Kong, particularly in residential care homes. Rehabilitation has beneficial effects on motor and swallowing function, activities of daily living, and quality of life in patients with Parkinson disease.7,8 Pilates exercise seems to be useful to improve balance and motor function of patients with Parkinson disease.
在新冠肺炎大流行期间,评估和预防虚弱和少肌症尤为重要。自2020年以来,新冠疫情一直是虚弱和少肌症的新风险因素。喂食问题在患有中风、晚期痴呆、神经退行性疾病(帕金森病)或肌萎缩性吞咽困难的老年患者中很常见。3尽管在一些老年病房实施了谨慎的手喂食,但在香港,尤其是在养老院,鼻胃管喂食很常见。康复对帕金森病患者的运动和吞咽功能、日常生活活动和生活质量有着有益的影响。7,8普拉提运动似乎有助于改善帕金森病患者平衡和运动功能。
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引用次数: 0
Statin-induced immune-mediated necrotising myopathy: a case report 他汀类药物诱导的免疫介导的坏死性肌病1例报告
Q4 Medicine Pub Date : 2021-12-17 DOI: 10.12809/ajgg-2020-440-cr
Ccd Leung, Wy Chu, CF Ko
{"title":"Statin-induced immune-mediated necrotising myopathy: a case report","authors":"Ccd Leung, Wy Chu, CF Ko","doi":"10.12809/ajgg-2020-440-cr","DOIUrl":"https://doi.org/10.12809/ajgg-2020-440-cr","url":null,"abstract":"","PeriodicalId":38338,"journal":{"name":"Asian Journal of Gerontology and Geriatrics","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45124175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Proton pump inhibitor–induced hypomagnesaemia leading to recurrent falls and delirium: a case report 质子泵抑制剂诱导的低镁血症导致复发性跌倒和谵妄:一例报告
Q4 Medicine Pub Date : 2021-12-17 DOI: 10.12809/ajgg-2020-431-cr
Tanya Joy Zapata Quicho, C. Chen
Older adults are at increased risk of developing hypomagnesaemia secondary to chronic use of proton pump inhibitors. We report a 73-yearold woman who presented with acute functional decline, recurrent falls, and cognitive impairment likely owing to unrecognised persistent hypomagnesaemia secondary to use of proton pump inhibitors.
由于长期使用质子泵抑制剂,老年人患低镁血症的风险增加。我们报告了一名73岁的女性,她表现出急性功能下降、反复跌倒和认知障碍,可能是由于使用质子泵抑制剂后出现的未被识别的持续性低镁血症。
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引用次数: 0
期刊
Asian Journal of Gerontology and Geriatrics
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