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Life-course trajectory of frailty and its clinical applications: a narrative review 衰弱的生命历程轨迹及其临床应用:叙述性回顾
Q4 Medicine Pub Date : 2021-01-01 DOI: 10.12809/ajgg-2020-429-ra
T. Auyeung, Swj Lee
Frailty is a condition indicating a reduced reserve in multiple systems and their disconnections. The whole body system cannot repair or recover by itself and may go into irreversible decline should interventions not be carried out early. This review discusses frailty in terms of the conceptual framework, pathophysiology, measurement and identification, lifecourse trajectory, and clinical application of assessment. It is anticipated that clinical application of the electronic frailty index expands to various specialties beyond geriatric medicine.
脆弱是指多个系统的储备减少及其断开的一种状态。整个身体系统不能自行修复或恢复,如果不及早进行干预,可能会进入不可逆转的衰退。本文从脆弱性的概念框架、病理生理学、测量和识别、生命历程轨迹以及评估的临床应用等方面进行了综述。预计电子虚弱指数的临床应用将扩展到老年医学以外的各个专业。
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引用次数: 1
Adaptation and validation of the Indonesian version of the FRAIL scale and the SARC-F in older adults 印度尼西亚版体弱量表和SARC-F在老年人中的适应和验证
Q4 Medicine Pub Date : 2021-01-01 DOI: 10.12809/ajgg-2020-436-oa
L. Dwipa, M. Apandi, Priyo Panji Utomo, Mira Hasmirani, A. Rakhimullah, F. A. Yulianto, Y. Pratiwi
Objective. To adapt and validate the Indonesian version of the FRAIL scale (Ina-FRAIL) and the SARC-F (Ina-SARC-F). Methods. The Ina-FRAIL and the Ina-SARC-F were developed through forwards-backwards translation, and their validity (itemtotal item correlations), internal consistency (Cronbach’s alpha), and test-retest reliability (kappa statistic) were determined. The diagnostic performance of the Ina-FRAIL and the Ina-SARC-F was evaluated using the receiver operating characteristic curve analysis. Results. A total of 101 (57 men and 44 women) and 64 (23 men and 41 women) patients were included in the validation of the Ina-FRAIL scale and the Ina-SARC-F, respectively. For the Ina-FRAIL scale, internal consistency coefficient was 0.530, and test-retest reliability was 0.951 (p<0.001). The correlation coefficients between the total score and items of fatigue, resistance, ambulation, illness, and loss of weight were 0.503, 0.813, 0.679, 0.561, and 0.317, respectively (all p<0.001). Correlation between the Ina-FRAIL scale and the Cardiovascular Health Study was strong (rs=0.696, p<0.001). Using the cut-off value of ≥2, the diagnostic performance of the Ina-FRAIL was 80% sensitivity and 70.4% specificity. For the Ina-SARC-F, internal consistency was 0.851, and test-retest reliability was 1.00 (p<0.001). The correlation coefficients between the total score and items of strength, ambulation, rising, climbing, and falls were 0.646, 0.775, 0.653, 0.685, and 0.580, respectively (all r>0.361 and p<0.001). Using the cut-off value of ≥3, the diagnosis performance of the Ina-SARC-F was 100% sensitivity and 61.7% specificity. Conclusions. The Ina-FRAIL scale and the Ina-SARC-F are valid and reliable tools to screen for frailty syndrome and sarcopenia, respectively.
目标。调整和验证印尼版本的脆弱量表(ina -脆弱)和SARC-F (Ina-SARC-F)。方法。通过前后翻译编制ina -脆弱量表和Ina-SARC-F量表,并测定其效度(项目总项目相关性)、内部一致性(Cronbach’s alpha)和重测信度(kappa统计量)。采用受者工作特征曲线分析评价ina -脆弱和Ina-SARC-F的诊断性能。结果。共有101例患者(男性57例,女性44例)和64例患者(男性23例,女性41例)被纳入ina -虚弱量表和Ina-SARC-F的验证。ina -脆弱量表的内部一致性系数为0.530,重测信度为0.951 (p0.361, p<0.001)。截断值≥3时,Ina-SARC-F的诊断敏感性为100%,特异性为61.7%。结论。ina -脆弱量表和Ina-SARC-F分别是筛查虚弱综合征和肌肉减少症的有效和可靠的工具。
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引用次数: 3
Osteosarcopenia and frailty: a review 骨肉瘤减少症和虚弱:综述
Q4 Medicine Pub Date : 2019-06-20 DOI: 10.12809/AJGG-2018-323-RA
K. Miu
Coexistence of osteoporosis and sarcopenia, known as osteosarcopenia, is well documented in frailty development in elderly people. Osteosarcopenia is associated with poor outcomes in terms of morbidity and mortality. This study aims to review the epidemiology and interactions of osteosarcopenia with frailty among older adults. Exercise seems to produce promising results in osteosarcopenic elderly people. Multidisciplinary assessment and management is the gold standard of care. Department of Rehabilitation and Extended Care, Wong Tai Sin Hospital, Hong Kong Correspondence to: Dr Ka Ying Doris Miu, Department of Rehabilitation and Extended Care, Wong Tai Sin Hospital, 124 Shatin Pass Road, Hong Kong. Email: miuky@ha.org.hk adjusted skeletal muscle mass of <7.26 kg/m2 in men and 5.45 kg/m2 in women as measured by DXA or <8.5 kg/m2 in men and 5.75 kg/m2 in women measured by BIA. A hand grip strength of <30 kg in men and <20 kg in women is considered at risk of sarcopenia. As body build differs between ethnic groups, the Asian Working Group for Sarcopenia (AWGS) defines sarcopenia as a height adjusted skeletal muscle mass of <7 kg/m2 in men and <5.4 kg/m2 in women measured by DXA and <7 kg/m2 in men and <5.7 kg/m2 in women measured by BIA, with a gait speed <0.8 m/s and a cut-off value of hand grip strength of <26 kg in men and <18 kg in women.8 In addition, there is a subgroup of elderly people who have both conditions with a higher risk of falls and fracture than those with osteoporosis or sarcopenia alone.9 This is known as sarco-osteopenia and later as osteosarcopenia. Studies have reported the association between osteosarcopenia and poor outcomes.10-12 Frailty is a major geriatric syndrome and is associated with greater prevalence of adverse health outcomes, including mortality, institutionalisation, falls, and recurrent hospitalisation.13-15 Frailty consists of multidimensional syndromes of loss of energy, physical activity, cognition, and health. There are many definitions of frailty.13,16,17 Fried et al16 defined frailty as the presence of three or more of the following syndromes: unintentional weight loss, INTRODUCTION With the growth of the ageing population, osteoporosis and sarcopenia are emerging.1,2 Osteoporosis is defined as low bone mass and micro-architectural deterioration of bone tissue.3 According to the World Health Organization (WHO) criteria, a t-score of bone mineral density of <–2.5 is considered as osteoporotic.4 In clinical settings, osteoporosis is defined by the WHO bone mineral density criteria or the occurrence of a fragility fracture. Osteoporosis leads to increased bone fragility and fracture risk. In Asian countries, the age-standardised annual incidence of hip fractures is higher than that in the USA and some European countries.5 Osteoporotic fractures in elderly people can result in hospitalisation, institutional care, impaired quality of life, disability, and even death.6 Sarcopenia is defined as decreased muscle m
骨质疏松症和少肌症(称为少骨症)的共存在老年人的虚弱发展中有很好的记录。骨肉瘤减少症与发病率和死亡率方面的不良结果有关。本研究旨在综述老年人骨骼肌减少症与虚弱的流行病学和相互作用。锻炼似乎对骨质疏松的老年人产生了有希望的效果。多学科评估和管理是护理的黄金标准。香港黄大仙医院康复及扩展护理科致:香港沙田帕斯道124号黄大仙院康复及扩展治疗科Ka Ying Doris Miu医生。电子邮件:miuky@ha.org.hk通过DXA测量的男性<7.26 kg/m2和女性5.45 kg/m2的调整骨骼肌质量,或者通过BIA测量的男子<8.5 kg/m2和妇女5.75 kg/m2。男性握力<30 kg,女性握力<20 kg被认为有少肌症的风险。由于不同种族的体型不同,亚洲肌肉减少症工作组(AWGS)将肌肉减少症定义为通过DXA测量的男性<7 kg/m2、女性<5.4 kg/m2、男性<7 mg/m2、女性<5.7 kg/m2的身高调整骨骼肌质量,步态速度<0.8 m/s,男性握力临界值<26 kg,女性<18 kg。8此外,有一组老年人同时患有这两种疾病,其跌倒和骨折的风险比单纯患有骨质疏松症或少肌症的人更高。9这被称为少肌症,后来又称为少骨症。研究报告了少骨症与不良预后之间的关系。10-12虚弱是一种主要的老年综合征,与更高的不良健康后果发生率有关,包括死亡率、住院、跌倒和反复住院。13-15虚弱由能量、体力活动、认知和健康损失的多方面综合征组成。虚弱有很多定义。13,16,17 Fried等人16将虚弱定义为存在以下三种或三种以上综合征:意外体重减轻,引言随着人口老龄化的增长,骨质疏松症和少肌症正在出现。1,2骨质疏松症被定义为骨组织的低骨量和微结构退化。3根据世界卫生组织(世界卫生组织)的标准,骨矿物质密度<-2.5的t评分被视为骨质疏松。4在临床环境中,骨质疏松症是由世界卫生组织骨密度标准或脆性骨折的发生定义的。骨质疏松症会增加骨骼脆性和骨折风险。在亚洲国家,髋部骨折的年龄标准化年发病率高于美国和一些欧洲国家。5老年人骨质疏松性骨折可能导致住院、机构护理、生活质量受损、残疾甚至死亡。6肌萎缩被定义为肌肉质量和身体表现下降,各国不同(表)。欧洲老年人肌肉减少症工作组(EWGSOP)将肌肉减少症定义为一种综合征,其特征是骨骼肌质量和力量的进行性和全身性丧失,并有出现身体残疾、生活质量差、,7可通过双能X射线吸收仪(DXA)或生物电阻抗分析(BIA)和/或低肌肉功能/力量进行诊断。EWGSOP将少肌症定义为步态速度<0.8 m/s,身高
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引用次数: 0
Malnutrition risk prevalence and clinical outcomes among acute hospital inpatients in Hong Kong 香港急症住院病人营养不良风险现况及临床结果
Q4 Medicine Pub Date : 2019-06-20 DOI: 10.12809/AJGG-2018-305-OA
T. Ting, CY. Wong, S. Y. Ng
Introduction. Studies have suggested that 20% to 50% of inpatients are malnourished. This study aimed to investigate the prevalence of malnutrition risk in inpatients at an acute hospital and to evaluate the association between nutritional risk and clinical outcomes. Methods. Records of 40,105 adult patients admitted to our hospital between January and December 2016 were retrieved. We recorded patient Malnutrition Screening Tool (MST) scores (range, 0–5) and outcomes after discharge from hospital such as length of hospital stay (LOS), 28-day emergency readmission rate, and death. The malnutrition risk was categorised into three levels according to MST score: low risk (0-1), medium risk (2), and high risk (≥3). We made comparisons among the three groups, and between the low-risk group and the mediumand high-risk (at-risk) group. Results. The prevalence of malnutrition risk was 9.2%. Malnutrition risk was 12.0% among those aged ≥65 years and 6.1% among those aged 18 to 65 years. The low-, mediumand high-risk groups differed significantly in terms of the mean patient age (64.2 vs. 70.8 vs. 73.7 years, p<0.01) and the mean LOS (4.2 vs. 6.4 vs. 7.4 days, p<0.001). The emergency readmission rate within 28 days was higher in at-risk patients than in low-risk patients (25.1% vs. 14.6%, odds ratio=2.0, p<0.001), as was the mortality rate (8.5% vs. 2.3%, odds ratio=3.9, p<0.001). Conclusion. Malnutrition is a common problem among hospitalised patients. The use of a validated malnutrition screening tool to lower the malnutrition risk is necessary. A multicentre cross-sectional study on the effect of malnutrition on clinical outcomes is needed for developing service-quality enhancement measures. 1 Dietetics Department, North District Hospital, New Territories, Hong Kong 2 Department of Surgery, North District Hospital, New Territories, Hong Kong 3 Central Nursing Department, North District Hospital, New Territories, Hong Kong Correspondence to: Dr Terry HY Ting, 1/F, Dietetics Department, North District Hospital, New Territories, Hong Kong. Email: tinghoyan@gmail.com intake owing to neurological disorders (including dysphagia) that decrease the ability to self-feed, sideeffects of drugs or treatments, or deterioration in taste and smell leading to a poor appetite.2 Malnutrition is more likely to develop in older adults with comorbid chronic conditions, impaired adaptation to inflammatory-catabolic states, or a heightened risk of acute diseases.3 By 2050, the number of older INTRODUCTION Malnutrition is defined as a state of nutrition in which an excess or deficiency of energy, macroand micro-nutrients causes adverse effects on clinical, functional, and economic outcomes.1 Malnutrition is common in health care settings, particularly in an acute care hospitals, when patients reduce their food
介绍研究表明,20%至50%的住院患者营养不良。本研究旨在调查急性医院住院患者营养不良风险的患病率,并评估营养风险与临床结果之间的关系。方法。检索了2016年1月至12月期间入住我院的40105名成年患者的记录。我们记录了患者营养不良筛查工具(MST)评分(范围,0-5)和出院后的结果,如住院时间(LOS)、28天急诊再次入院率和死亡。根据MST评分,营养不良风险分为三个级别:低风险(0-1)、中风险(2)和高风险(≥3)。我们在三组之间以及低风险组和中高风险组之间进行了比较。后果营养不良风险的患病率为9.2%,≥65岁人群的营养不良风险为12.0%,18-65岁人群为6.1%。低、中、高危组的平均患者年龄(64.2 vs.70.8 vs.73.7岁,p<0.01)和平均LOS(4.2 vs.6.4 vs.7.4天,p<0.001)存在显著差异。高危患者28天内的急诊再入院率高于低风险患者(25.1%vs.14.6%,比值比=2.0,p<0.001),死亡率也是如此(8.5%对2.3%,比值比=3.9,p<0.001)。营养不良是住院病人的常见问题。使用经过验证的营养不良筛查工具来降低营养不良风险是必要的。需要对营养不良对临床结果的影响进行多中心横断面研究,以制定提高服务质量的措施。1香港新界北区医院饮食科2香港新界北区医院外科3香港新界北区医院中央护理部致香港新界北区医院一楼Terry HY Ting医生。电子邮件:tinghoyan@gmail.com由于神经系统疾病(包括吞咽困难)导致的进食能力下降,药物或治疗的副作用,或味觉和嗅觉下降导致食欲下降。2老年人更容易出现营养不良,患有慢性病,对炎症分解代谢状态的适应受损,或患急性疾病的风险增加。3到2050年,老年人的数量引言营养不良被定义为一种营养状态,在这种状态下,能量、宏量和微量营养素的过量或缺乏会对临床、功能和经济结果产生不利影响。1营养不良在医疗保健环境中很常见,尤其是在急性护理医院,当患者减少食物时
{"title":"Malnutrition risk prevalence and clinical outcomes among acute hospital inpatients in Hong Kong","authors":"T. Ting, CY. Wong, S. Y. Ng","doi":"10.12809/AJGG-2018-305-OA","DOIUrl":"https://doi.org/10.12809/AJGG-2018-305-OA","url":null,"abstract":"Introduction. Studies have suggested that 20% to 50% of inpatients are malnourished. This study aimed to investigate the prevalence of malnutrition risk in inpatients at an acute hospital and to evaluate the association between nutritional risk and clinical outcomes. Methods. Records of 40,105 adult patients admitted to our hospital between January and December 2016 were retrieved. We recorded patient Malnutrition Screening Tool (MST) scores (range, 0–5) and outcomes after discharge from hospital such as length of hospital stay (LOS), 28-day emergency readmission rate, and death. The malnutrition risk was categorised into three levels according to MST score: low risk (0-1), medium risk (2), and high risk (≥3). We made comparisons among the three groups, and between the low-risk group and the mediumand high-risk (at-risk) group. Results. The prevalence of malnutrition risk was 9.2%. Malnutrition risk was 12.0% among those aged ≥65 years and 6.1% among those aged 18 to 65 years. The low-, mediumand high-risk groups differed significantly in terms of the mean patient age (64.2 vs. 70.8 vs. 73.7 years, p<0.01) and the mean LOS (4.2 vs. 6.4 vs. 7.4 days, p<0.001). The emergency readmission rate within 28 days was higher in at-risk patients than in low-risk patients (25.1% vs. 14.6%, odds ratio=2.0, p<0.001), as was the mortality rate (8.5% vs. 2.3%, odds ratio=3.9, p<0.001). Conclusion. Malnutrition is a common problem among hospitalised patients. The use of a validated malnutrition screening tool to lower the malnutrition risk is necessary. A multicentre cross-sectional study on the effect of malnutrition on clinical outcomes is needed for developing service-quality enhancement measures. 1 Dietetics Department, North District Hospital, New Territories, Hong Kong 2 Department of Surgery, North District Hospital, New Territories, Hong Kong 3 Central Nursing Department, North District Hospital, New Territories, Hong Kong Correspondence to: Dr Terry HY Ting, 1/F, Dietetics Department, North District Hospital, New Territories, Hong Kong. Email: tinghoyan@gmail.com intake owing to neurological disorders (including dysphagia) that decrease the ability to self-feed, sideeffects of drugs or treatments, or deterioration in taste and smell leading to a poor appetite.2 Malnutrition is more likely to develop in older adults with comorbid chronic conditions, impaired adaptation to inflammatory-catabolic states, or a heightened risk of acute diseases.3 By 2050, the number of older INTRODUCTION Malnutrition is defined as a state of nutrition in which an excess or deficiency of energy, macroand micro-nutrients causes adverse effects on clinical, functional, and economic outcomes.1 Malnutrition is common in health care settings, particularly in an acute care hospitals, when patients reduce their food","PeriodicalId":38338,"journal":{"name":"Asian Journal of Gerontology and Geriatrics","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44325304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Hip osteomyelitis secondary to pressure injury: a case report 髋关节骨髓炎继发于压伤:1例报告
Q4 Medicine Pub Date : 2019-06-20 DOI: 10.12809/AJGG-2018-300-CR
L. Onn, S. Teo
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引用次数: 2
Optimal rehabilitation and community integration for family caregivers of stroke patients 脑卒中患者家庭护理人员的最佳康复和社区整合
Q4 Medicine Pub Date : 2019-06-20 DOI: 10.12809/AJGG-V14N1-ED
V. Lou
Stroke is the second most common cause of disability-adjusted life years worldwide, and the incidence of stroke is highest in east Asia.1 In Hong Kong, every year approximately 22,000 people who suffer from stroke are discharged to home or institutional care.2 Risk factors for stroke are mainly associated with three aspects, including factors such as high systolic blood pressure and high level of cholesterol; behavioural factors such as smoking, physical inactivity, and diet; and environmental factors such as air pollution. Stroke survivors have three silent needs during rehabilitation: (1) need for rehabilitation of physical, cognitive, psychological and social functions, (2) need to regain an active lifestyle corresponding to their physical and/or mental limitations, and (3) need for environmental adaptation to regain an active lifestyle in a safe, accessible, and empowering environment.3
中风是全球第二常见的致残原因-调整后的寿命年数,中风的发病率在东亚最高。1在香港,每年约有22000名中风患者出院到家中或机构护理。2中风的风险因素主要与三个方面有关,包括诸如高收缩压和高胆固醇水平的因素;吸烟、缺乏运动和饮食等行为因素;以及空气污染等环境因素。中风幸存者在康复过程中有三种无声的需求:(1)身体、认知、心理和社会功能的康复需求,(2)需要恢复与其身体和/或精神限制相对应的积极生活方式,以及(3)需要环境适应,以便在安全、可及和赋权的环境中恢复积极的生活方式。3
{"title":"Optimal rehabilitation and community integration for family caregivers of stroke patients","authors":"V. Lou","doi":"10.12809/AJGG-V14N1-ED","DOIUrl":"https://doi.org/10.12809/AJGG-V14N1-ED","url":null,"abstract":"Stroke is the second most common cause of disability-adjusted life years worldwide, and the incidence of stroke is highest in east Asia.1 In Hong Kong, every year approximately 22,000 people who suffer from stroke are discharged to home or institutional care.2 Risk factors for stroke are mainly associated with three aspects, including factors such as high systolic blood pressure and high level of cholesterol; behavioural factors such as smoking, physical inactivity, and diet; and environmental factors such as air pollution. Stroke survivors have three silent needs during rehabilitation: (1) need for rehabilitation of physical, cognitive, psychological and social functions, (2) need to regain an active lifestyle corresponding to their physical and/or mental limitations, and (3) need for environmental adaptation to regain an active lifestyle in a safe, accessible, and empowering environment.3","PeriodicalId":38338,"journal":{"name":"Asian Journal of Gerontology and Geriatrics","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48149526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development and validation of a modified Frailty Risk Index as a predictor of mortality in rural elderly people 改进的衰弱风险指数作为农村老年人死亡率预测因子的开发和验证
Q4 Medicine Pub Date : 2019-06-20 DOI: 10.12809/AJGG-2018-315-OA
Sunil Kumar, Shraddha Jain, A. Wanjari, S. Mandal
Background. Frailty is a reversible age-related condition characterised by declines across multiple physiologic systems and associated with an increased risk of mortality or unplanned hospitalisation. We developed and validated a new frailty index that is easy to apply in elderly people in rural India and has predictive accuracy for all-cause mortality at 6 and 12 months. Methods. 1000 participants aged >60 years who were admitted to a geriatric unit of a rural hospital for screening or treatment of any illness were recruited for development and validation of the Frailty Index in Rural Elderly – Mental status, Activities of daily living, Depression, and Events (FIRE-MADE), which combines the Cumulative Deficits Model and the Comprehensive Geriatric Assessment Model and takes into account of four domains: physical, cognitive, psychosocial, and functional. Results. The FIRE-MADE score increased with age and was higher in men than in women. Higher FIRE-MADE score was associated with higher rates of mortality and unplanned hospitalisation. In multivariable analysis, predictors for mortality were Mini-Mental State Examination, activities of daily living, ischaemic heart disease, history of stroke, and polypharmacy. In Kaplan-Meier survival analysis, 4.9%, 7.1%, and 16.7% of participants with mild (FIRE-MADE score, 0.3-0.4), moderate (0.5-0.6), and severe (>0.7) frailty died at the end of 1 year. The cut-off values for mortality and unplanned hospitalisation were 0.32 and 0.27, respectively, with the area under the receiver operating characteristic curve for the severity being 0.883 and 0.794, respectively. Compared with the Longitudinal Aging Study Amsterdam frailty index score in predicting mortality and unplanned hospitalisation, the FIRE-MADE score had positive predictive values of 88.89% and 88.89%, respectively, and negative predictive values of 65.93% and 41.10%, respectively. Association between the two indices was strong. Conclusions. FIRE-MADE is easy to apply in clinical practice as a screening tool to detect frailty in elderly people in rural India.
{"title":"Development and validation of a modified Frailty Risk Index as a predictor of mortality in rural elderly people","authors":"Sunil Kumar, Shraddha Jain, A. Wanjari, S. Mandal","doi":"10.12809/AJGG-2018-315-OA","DOIUrl":"https://doi.org/10.12809/AJGG-2018-315-OA","url":null,"abstract":"Background. Frailty is a reversible age-related condition characterised by declines across multiple physiologic systems and associated with an increased risk of mortality or unplanned hospitalisation. We developed and validated a new frailty index that is easy to apply in elderly people in rural India and has predictive accuracy for all-cause mortality at 6 and 12 months. Methods. 1000 participants aged >60 years who were admitted to a geriatric unit of a rural hospital for screening or treatment of any illness were recruited for development and validation of the Frailty Index in Rural Elderly – Mental status, Activities of daily living, Depression, and Events (FIRE-MADE), which combines the Cumulative Deficits Model and the Comprehensive Geriatric Assessment Model and takes into account of four domains: physical, cognitive, psychosocial, and functional. Results. The FIRE-MADE score increased with age and was higher in men than in women. Higher FIRE-MADE score was associated with higher rates of mortality and unplanned hospitalisation. In multivariable analysis, predictors for mortality were Mini-Mental State Examination, activities of daily living, ischaemic heart disease, history of stroke, and polypharmacy. In Kaplan-Meier survival analysis, 4.9%, 7.1%, and 16.7% of participants with mild (FIRE-MADE score, 0.3-0.4), moderate (0.5-0.6), and severe (>0.7) frailty died at the end of 1 year. The cut-off values for mortality and unplanned hospitalisation were 0.32 and 0.27, respectively, with the area under the receiver operating characteristic curve for the severity being 0.883 and 0.794, respectively. Compared with the Longitudinal Aging Study Amsterdam frailty index score in predicting mortality and unplanned hospitalisation, the FIRE-MADE score had positive predictive values of 88.89% and 88.89%, respectively, and negative predictive values of 65.93% and 41.10%, respectively. Association between the two indices was strong. Conclusions. FIRE-MADE is easy to apply in clinical practice as a screening tool to detect frailty in elderly people in rural India.","PeriodicalId":38338,"journal":{"name":"Asian Journal of Gerontology and Geriatrics","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42214935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 16
Effect of multidisciplinary prehabilitation-rehabilitation on outcomes after colorectal surgery in elderly patients 多学科预康复对老年结直肠癌术后预后的影响
Q4 Medicine Pub Date : 2019-06-20 DOI: 10.12809/AJGG-2018-304-OA
Nicholette Goh, K. Tan
Objective. To determine the effect of the start-to-finish programme by comparing outcomes of elderly patients who underwent colorectal surgery before and after introduction of the programme. Methods: Data of consecutive patients aged ≥75 years who underwent major colorectal surgery (open, minimally invasive, elective, or emergency) between February 2007 and November 2015 at our institution were collected prospectively. Postoperative outcomes of patients were compared before and after the July 2013 introduction of the start-to-finish programme. Patients were risk-stratified for decision on whether prehabilitation was required, based on frailty syndrome, weighted Charlson Comorbidity Index, and ambulatory status. Frailty was defined as presentation of three or more of the following criteria: unintentional weight loss, self-reported exhaustion, weakness (grip strength), slow walking speed, and low physical activity. Outcome measures included discharge destination, functional decline in terms of a loss of ≥10 points in the Barthel Index at postoperative week 6, length of hospital stay, postoperative complication in terms of a Clavien-Dindo score of ≥3, and 30-day mortality. Results: A total of 121 geriatric patients were recruited and followed up for a mean duration of 36 months. Of whom, 49 (40.1%) were recruited after the introduction of start-to-finish programme in July 2013. 34 (28.1%) of the 121 patients were determined to be frail. In multivariate analysis, frailty was the only predictor of discharge destination (odds ratio [OR]=6.067, p=0.001). Patients with a Clavien-Dindo score of ≥3 were more likely to have functional decline at postoperative week 6 (OR=83.926, p=0.003). The start-to-finish programme (OR=0.067, p=0.023) and elective surgery (OR=0.091, p=0.024) were associated with maintenance of functional. Frailty was associated with discharge to facilities other than home (OR=6.067, p=0.001) and a steeper decline on longer-term follow-up. Conclusion: The start-to-finish programme had a positive effect on reducing functional decline after colorectal surgery. Frail patients and patients with major complications require special attention to mitigate the steep functional decline.
客观的通过比较在引入该计划之前和之后接受结直肠手术的老年患者的结果来确定从开始到结束的计划的效果。方法:前瞻性收集2007年2月至2015年11月期间在我院接受大肠癌手术(开放式、微创、选择性或急诊)的年龄≥75岁的连续患者的数据。比较了2013年7月实施从开始到结束方案前后患者的术后结果。根据虚弱综合征、加权Charlson合并症指数和动态状况,对患者进行风险分层,以决定是否需要进行康复。虚弱被定义为以下三个或三个以上标准的表现:意外体重减轻、自我报告的疲惫、虚弱(握力)、行走速度慢和体力活动量低。结果指标包括出院目的地、术后第6周Barthel指数损失≥10分的功能下降、住院时间、Clavien-Dindo评分≥3的术后并发症以及30天死亡率。结果:共招募了121名老年患者,并进行了平均36个月的随访。其中49人(40.1%)是在2013年7月开始实施从开始到结束的方案后被招募的。121名患者中有34名(28.1%)被确定为身体虚弱。在多变量分析中,虚弱是出院目的地的唯一预测因素(比值比[OR]=6.067,p=0.001)。Clavien-Dindo评分≥3的患者在术后第6周更有可能出现功能下降(OR=83.926,p=0.003)。从开始到结束的方案(OR=0.067,p=0.023)和选择性手术(OR=0.091,p=0.024)与功能维持有关。虚弱与出院到家庭以外的设施有关(OR=6.067,p=0.001),并且在长期随访中下降幅度更大。结论:从开始到结束的方案对减少结直肠手术后功能下降有积极作用。虚弱的患者和有严重并发症的患者需要特别注意,以缓解急剧的功能下降。
{"title":"Effect of multidisciplinary prehabilitation-rehabilitation on outcomes after colorectal surgery in elderly patients","authors":"Nicholette Goh, K. Tan","doi":"10.12809/AJGG-2018-304-OA","DOIUrl":"https://doi.org/10.12809/AJGG-2018-304-OA","url":null,"abstract":"Objective. To determine the effect of the start-to-finish programme by comparing outcomes of elderly patients who underwent colorectal surgery before and after introduction of the programme. Methods: Data of consecutive patients aged ≥75 years who underwent major colorectal surgery (open, minimally invasive, elective, or emergency) between February 2007 and November 2015 at our institution were collected prospectively. Postoperative outcomes of patients were compared before and after the July 2013 introduction of the start-to-finish programme. Patients were risk-stratified for decision on whether prehabilitation was required, based on frailty syndrome, weighted Charlson Comorbidity Index, and ambulatory status. Frailty was defined as presentation of three or more of the following criteria: unintentional weight loss, self-reported exhaustion, weakness (grip strength), slow walking speed, and low physical activity. Outcome measures included discharge destination, functional decline in terms of a loss of ≥10 points in the Barthel Index at postoperative week 6, length of hospital stay, postoperative complication in terms of a Clavien-Dindo score of ≥3, and 30-day mortality. Results: A total of 121 geriatric patients were recruited and followed up for a mean duration of 36 months. Of whom, 49 (40.1%) were recruited after the introduction of start-to-finish programme in July 2013. 34 (28.1%) of the 121 patients were determined to be frail. In multivariate analysis, frailty was the only predictor of discharge destination (odds ratio [OR]=6.067, p=0.001). Patients with a Clavien-Dindo score of ≥3 were more likely to have functional decline at postoperative week 6 (OR=83.926, p=0.003). The start-to-finish programme (OR=0.067, p=0.023) and elective surgery (OR=0.091, p=0.024) were associated with maintenance of functional. Frailty was associated with discharge to facilities other than home (OR=6.067, p=0.001) and a steeper decline on longer-term follow-up. Conclusion: The start-to-finish programme had a positive effect on reducing functional decline after colorectal surgery. Frail patients and patients with major complications require special attention to mitigate the steep functional decline.","PeriodicalId":38338,"journal":{"name":"Asian Journal of Gerontology and Geriatrics","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42013163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Impact of acute geriatric services for nursing home residents on emergency department presentation and hospitalisation 老年急症护理服务对急诊科表现及住院的影响
Q4 Medicine Pub Date : 2018-12-30 DOI: 10.12809/ajgg-2017-276-oa
S. L. Ling, Chia-Ti Cheng, Frank, Liu, D. Irwanto, F. Kohler, Matthew Smith, D. Chan
Background. Prior to May 2015, our hospital provided only non-urgent geriatric services for nursing home residents. Thereafter, the Connecting Care Programme was introduced to provide acute geriatric services, including administration of intravenous antibiotics and fluids and a variety of other procedures. This audit aimed to investigate the impact of acute geriatric services for nursing home residents on emergency department presentation and hospitalisation. Methods. Medical records of nursing home residents who presented to the Bankstown-Lidcombe Hospital before (from May to August 2014) and after (from May to August 2015) the Connecting Care Programme were retrospectively reviewed. The two groups were compared in terms of emergency department presentation and discharge rates. Results. Respectively for the group before and after the programme, of all presentations to the emergency department, 276 and 318 involved nursing home residents (6.1% vs 7.1%, p=0.056). Of these, 106 and 167 were discharged from the emergency department (38.4% vs 52.5%, odds ratio=1.76, 95% confidence interval=1.2-2.4, p=0.0008). The Connecting Care Programme increased the discharge rate in those with a diagnosis of fall without fracture (70% vs 88%, p=0.021), respiratory (11% vs 31%, p=0.020), gastrointestinal (34% vs 50%, p=0.025), or cardiovascular (24% vs 60%, p=0.010) complaints. Conclusion. The Connecting Care Programme resulted in an increased discharge rate and decreased hospital admission rate for nursing home residents who presented with fall without fracture, respiratory, gastrointestinal, or cardiovascular complaints. The programme may enable better utilisation of healthcare resources.
背景。2015年5月之前,我院仅为养老院居民提供非紧急老年服务。此后,实施了连接护理方案,以提供急性老年服务,包括静脉注射抗生素和液体以及各种其他程序。本审计旨在调查急性老年护理服务对急诊科表现和住院的影响。方法。回顾性回顾了在连接护理计划之前(2014年5月至8月)和之后(2015年5月至8月)到bankown - lidcombe医院就诊的养老院居民的医疗记录。比较两组在急诊科的表现和出院率。结果。在计划之前和之后的小组中,所有到急诊科的报告中,276和318涉及养老院居民(6.1%对7.1%,p=0.056)。其中106例和167例从急诊科出院(38.4% vs 52.5%,优势比=1.76,95%可信区间=1.2 ~ 2.4,p=0.0008)。连接护理计划提高了诊断为跌倒无骨折的患者的出院率(70%对88%,p=0.021)、呼吸道疾病(11%对31%,p=0.020)、胃肠道疾病(34%对50%,p=0.025)或心血管疾病(24%对60%,p=0.010)。结论。“连接护理计划”提高了养老院居民的出院率,降低了住院率,这些人出现了跌倒,但没有骨折、呼吸系统、胃肠道或心血管疾病。该方案可使医疗资源得到更好的利用。
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引用次数: 2
Can home-based rehabilitation services facilitate rehabilitation transition from hospital to community? 家居康复服务能否促进康复从医院过渡到社区?
Q4 Medicine Pub Date : 2018-12-30 DOI: 10.12809/ajgg-2018-320-letter
Iris F. K. Lee, F. Yau, S. Yim, D. Lee
In Hong Kong, the overload of the health care system and the heavy burden on caregivers urge the revisit of the local community rehabilitation services. Owing to the ageing population, high demand for hospital beds inevitably leads to early discharge of patients. Post-discharge rehabilitation services thus become exceptionally important to older patients. The transition period from hospital to home is critical for rehabilitation, as it affects patient recovery and adjustment to daily activities and quality of life.1 In addition, the stress of caregivers should not be overlooked. For instance, in 2017 an old man killed his wife, who had physical deconditioning at home, because of stress from prolonged caregiving.2 To prevent such tragedies, rehabilitation services should provide caregiver support such as skill training and referral to social services. However, there are gaps in the existing subsidised rehabilitation services for the older people in Hong Kong.
在香港,医疗体系的超负荷和护理人员的沉重负担促使人们重新审视当地的社区康复服务。由于人口老龄化,对病床的高需求不可避免地导致患者提前出院。因此,出院后的康复服务对老年患者来说变得格外重要。从医院到家庭的过渡期对康复至关重要,因为这会影响患者的康复和对日常活动的适应以及生活质量。1此外,护理人员的压力也不容忽视。例如,2017年,一名老人因长期护理带来的压力,杀死了在家中身体不适的妻子。2为了防止此类悲剧的发生,康复服务应提供护理人员支持,如技能培训和社会服务转介。然而,香港现时为长者提供的资助康复服务仍有缺口。
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引用次数: 0
期刊
Asian Journal of Gerontology and Geriatrics
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