Pub Date : 2019-03-01DOI: 10.7546/ijba.2019.23.1.71-86
I. Laktionov, O. Vovna, Yevhen O. Bashkov, A. Zori, V. Lebediev
The article presents results of field testing and experimental studies on improvement of the computer-oriented method of aggregation and processing of measurement information on microclimate parameters of industrial greenhouses. The technology was developed and tested in the laboratory. It consists of a hardware component based on Arduino Mega 2560 & Ethernet Shield W5100 and modern sensor devices, a software module based on Simulink Support Package for Arduino Hardware and a remote database of monitoring results on the ThingSpeak server. The technology proposed in the article has a modular structure and is adaptive to types and periods of vegetation of cultivated crops. The obtained research results constitute scientific and practical basis for conducting further priority research on implementation of the developed technology into actual production conditions for growing protected crops.
本文介绍了改进面向计算机的工业温室小气候参数测量信息汇总和处理方法的现场测试和实验研究结果。这项技术是在实验室中开发和测试的。它包括一个基于Arduino Mega 2560和以太网屏蔽W5100的硬件组件和现代传感器设备，一个基于用于Arduino硬件的Simulink支持包的软件模块和ThingSpeak服务器上的远程监测结果数据库。本文提出的技术具有模块化结构，适用于种植作物的植被类型和时期。所获得的研究结果为进一步优先研究将所开发的技术应用于种植保护作物的实际生产条件奠定了科学和实践基础。
{"title":"Improved Computer-oriented Method for Processing of Measurement Information on Greenhouse Microclimate","authors":"I. Laktionov, O. Vovna, Yevhen O. Bashkov, A. Zori, V. Lebediev","doi":"10.7546/ijba.2019.23.1.71-86","DOIUrl":"https://doi.org/10.7546/ijba.2019.23.1.71-86","url":null,"abstract":"The article presents results of field testing and experimental studies on improvement of the computer-oriented method of aggregation and processing of measurement information on microclimate parameters of industrial greenhouses. The technology was developed and tested in the laboratory. It consists of a hardware component based on Arduino Mega 2560 & Ethernet Shield W5100 and modern sensor devices, a software module based on Simulink Support Package for Arduino Hardware and a remote database of monitoring results on the ThingSpeak server. The technology proposed in the article has a modular structure and is adaptive to types and periods of vegetation of cultivated crops. The obtained research results constitute scientific and practical basis for conducting further priority research on implementation of the developed technology into actual production conditions for growing protected crops.","PeriodicalId":38867,"journal":{"name":"International Journal Bioautomation","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47022920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-03-01DOI: 10.7546/IJBA.2019.23.1.117-129
Yanfeng Liu, Lei-Yi Li, Jing Gao
This paper proposes the design and the implementation of a Spark parallelization plan for improving the Smith-Waterman (SW) algorithm, named the Spark-OSW algorithm. Then, the Spark-OSW was verified through accuracy, performance and acceleration tests. The results show that the proposed algorithm achieved 100% accuracy, ran much faster than the SW, and performed well in cluster environment. The research findings shed important new light on the database search for gene sequences.
{"title":"An Improved Smith-Waterman Algorithm Based on Spark Parallelization","authors":"Yanfeng Liu, Lei-Yi Li, Jing Gao","doi":"10.7546/IJBA.2019.23.1.117-129","DOIUrl":"https://doi.org/10.7546/IJBA.2019.23.1.117-129","url":null,"abstract":"This paper proposes the design and the implementation of a Spark parallelization plan for improving the Smith-Waterman (SW) algorithm, named the Spark-OSW algorithm. Then, the Spark-OSW was verified through accuracy, performance and acceleration tests. The results show that the proposed algorithm achieved 100% accuracy, ran much faster than the SW, and performed well in cluster environment. The research findings shed important new light on the database search for gene sequences.","PeriodicalId":38867,"journal":{"name":"International Journal Bioautomation","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47725846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-03-01DOI: 10.7546/IJBA.2019.23.1.1-12
M. Al-Khayyat
The RecA protein has an essential role in DNA recombination and repair which is mediated by its ability to bind ATP/ADP. SWISS-MODEL, an online automated server, was used to predict its tertiary structure of C. jejuni RecA. Four evaluation tools were used for quality assessment of the constructed model: QMEAN6, ERRAT, ANOLEA and PROCHECK. Quality assessments indicated that the model was of high quality and reliable for docking experiments. A total of forty natural products were used in docking the model by Hex 8.0.0 and ArgusLab 4.0.1 using ADP as control. Ten compounds had docking scores higher than that of ADP (-8.61 Kcal/mol) in ArgusLab 4.0.1 where quercetin had the highest docking score of -10.34 Kcal/mol. In Hex 8.0.0 docking, only cucurmin, taxifolin, isoquercitrin and vitexin had docking scores higher than that of ADP. These natural occurring compounds may be possible inhibitors of ATPase activity and, therefore, may be further analyzed to develop new antimicrobials targeting RecA in pathogenic bacteria.
{"title":"In silico Homology Modeling and Docking Studies of RecA from Campylobacter jejuni","authors":"M. Al-Khayyat","doi":"10.7546/IJBA.2019.23.1.1-12","DOIUrl":"https://doi.org/10.7546/IJBA.2019.23.1.1-12","url":null,"abstract":"The RecA protein has an essential role in DNA recombination and repair which is mediated by its ability to bind ATP/ADP. SWISS-MODEL, an online automated server, was used to predict its tertiary structure of C. jejuni RecA. Four evaluation tools were used for quality assessment of the constructed model: QMEAN6, ERRAT, ANOLEA and PROCHECK. Quality assessments indicated that the model was of high quality and reliable for docking experiments. A total of forty natural products were used in docking the model by Hex 8.0.0 and ArgusLab 4.0.1 using ADP as control. Ten compounds had docking scores higher than that of ADP (-8.61 Kcal/mol) in ArgusLab 4.0.1 where quercetin had the highest docking score of -10.34 Kcal/mol. In Hex 8.0.0 docking, only cucurmin, taxifolin, isoquercitrin and vitexin had docking scores higher than that of ADP. These natural occurring compounds may be possible inhibitors of ATPase activity and, therefore, may be further analyzed to develop new antimicrobials targeting RecA in pathogenic bacteria.","PeriodicalId":38867,"journal":{"name":"International Journal Bioautomation","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42149830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Through different water-soil ratio, oscillation time, ion contents and soil salt quantity, the correlation and regression between the whole soil salinity in oasis-desert ecotones in Tarim basin and electro conductivity of soil soak-out-liquid have been studied by electric conductivity methods. The results indicated: when water-soil ratio was 1:1-6:1, there was significantly correlation between electro conductibility and whole-salt quantity. But the 5:1 water-soil ratio is better according to the soil characteristic in this locality. After the oscillation time of soil samples was 10 minutes under the 5:1 water-soil ratio, the electro conductibility of soak-out-liquid there was not marked difference. The correlation between ion of comparative large contents and the electro conductibility soak-out liquid was very marked. When soil salinity is large, linear functions can be used to better measure the whole salt quantity of this local by subsection analysis.
{"title":"Experimental Study on Relation between Whole-salt Quantity and Electric Conductivity","authors":"Yu Zhang, Xichun Jia, X. Lai, Yin-Chung Huang, Changfu Road Guangzhou China Environment","doi":"10.7546/IJBA.2019.23.1.97-104","DOIUrl":"https://doi.org/10.7546/IJBA.2019.23.1.97-104","url":null,"abstract":"Through different water-soil ratio, oscillation time, ion contents and soil salt quantity, the correlation and regression between the whole soil salinity in oasis-desert ecotones in Tarim basin and electro conductivity of soil soak-out-liquid have been studied by electric conductivity methods. The results indicated: when water-soil ratio was 1:1-6:1, there was significantly correlation between electro conductibility and whole-salt quantity. But the 5:1 water-soil ratio is better according to the soil characteristic in this locality. After the oscillation time of soil samples was 10 minutes under the 5:1 water-soil ratio, the electro conductibility of soak-out-liquid there was not marked difference. The correlation between ion of comparative large contents and the electro conductibility soak-out liquid was very marked. When soil salinity is large, linear functions can be used to better measure the whole salt quantity of this local by subsection analysis.","PeriodicalId":38867,"journal":{"name":"International Journal Bioautomation","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44413903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-03-01DOI: 10.7546/ijba.2019.23.1.51-60
Z. Zulkarnain, H. Sujuti, D. Soeatmadji, Huswo Utomo, A. Aulanni’am
The thyroid-stimulating hormone receptor (TSHR) is one of the thyroid antigens responsible for Graves’ disease and acts as a biomarker for early detection. The purpose of this study was to computationally compare the effectiveness of TSHR56 and TSHR169 fragments in binding to the thyroid-stimulating human monoclonal autoantibody (M22) at the molecular level. The 3D model of M22 was obtained from RCSB (ID 3G04), while the TSHR antigen models were submitted to homology modeling using SWISSMODEL and PhyreV2.0 server to predict the protein structures. The model was validated by generating a Ramachandran plot with the RAMPAGE server. Prediction of the molecular interaction between TSHR and M22 was performed using the HADDOCK web server (version 2.2). Analysis of the binding affinity was conducted using the PRODIGY server. Interactions within the TSHR-M22 complex were analyzed using DIMPLOT. The antigen models had reliability scores of 100% and 97.7% for TSHR56 and TSHR169, respectively. The results of the molecular docking analysis revealed a better HADDOCK score for TSHR169 (-144.7 ± 2.4) INT. J. BIOAUTOMATION, 2019, 23(1), 51-60 doi: 10.7546/ijba.2019.23.1.51-60 52 compared to TSHR56 (-53.3 ± 10.1). However, the affinity of TSHR56 (-10.1 Kcal/mol) and TSHR169 (-10.2 Kcal/mol) were not significantly different. The results of the TSHR-M22 interaction specificity analysis suggested that TSHR169 is superior to TSHR56, as the number of interacting amino acids was comparable to the control (TSHR260-M22). It can be concluded that TSHR169 represents a specific full-length TSHR antigen and can be developed as biomarker for Graves’ disease.
{"title":"TSHR169 Antigen Specifically Binds to the Thyroid-stimulating Autoantibody, Representing an Effective Biomarker for Graves’ Disease","authors":"Z. Zulkarnain, H. Sujuti, D. Soeatmadji, Huswo Utomo, A. Aulanni’am","doi":"10.7546/ijba.2019.23.1.51-60","DOIUrl":"https://doi.org/10.7546/ijba.2019.23.1.51-60","url":null,"abstract":"The thyroid-stimulating hormone receptor (TSHR) is one of the thyroid antigens responsible for Graves’ disease and acts as a biomarker for early detection. The purpose of this study was to computationally compare the effectiveness of TSHR56 and TSHR169 fragments in binding to the thyroid-stimulating human monoclonal autoantibody (M22) at the molecular level. The 3D model of M22 was obtained from RCSB (ID 3G04), while the TSHR antigen models were submitted to homology modeling using SWISSMODEL and PhyreV2.0 server to predict the protein structures. The model was validated by generating a Ramachandran plot with the RAMPAGE server. Prediction of the molecular interaction between TSHR and M22 was performed using the HADDOCK web server (version 2.2). Analysis of the binding affinity was conducted using the PRODIGY server. Interactions within the TSHR-M22 complex were analyzed using DIMPLOT. The antigen models had reliability scores of 100% and 97.7% for TSHR56 and TSHR169, respectively. The results of the molecular docking analysis revealed a better HADDOCK score for TSHR169 (-144.7 ± 2.4) INT. J. BIOAUTOMATION, 2019, 23(1), 51-60 doi: 10.7546/ijba.2019.23.1.51-60 52 compared to TSHR56 (-53.3 ± 10.1). However, the affinity of TSHR56 (-10.1 Kcal/mol) and TSHR169 (-10.2 Kcal/mol) were not significantly different. The results of the TSHR-M22 interaction specificity analysis suggested that TSHR169 is superior to TSHR56, as the number of interacting amino acids was comparable to the control (TSHR260-M22). It can be concluded that TSHR169 represents a specific full-length TSHR antigen and can be developed as biomarker for Graves’ disease.","PeriodicalId":38867,"journal":{"name":"International Journal Bioautomation","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45118888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-03-01DOI: 10.7546/ijba.2019.23.1.61-70
I. Dotsinsky, T. Stoyanov
Each ECG analysis begins with the detection of the QRS complex, which is the most distinguishable wave for initial investigation. Long ago we published an algorithm for ventricular beats (VB) detection in single ECG lead. The classification of normal QRS complexes is based on the slope, the amplitude and the width of the ECG waves. Other criteria recognize ventricular ectopic beats (EB) by presence of biphasic beats and separate premature EB from the already detected QRS complexes. The aim of this paper is to place the MATLAB program of our algorithm at disposal to the readers (supplementary MATLAB codes) looking forward to more successful ECG investigations.
{"title":"Continuously Tested and Used QRS Detection Algorithm: Free Access to the MATLAB Code","authors":"I. Dotsinsky, T. Stoyanov","doi":"10.7546/ijba.2019.23.1.61-70","DOIUrl":"https://doi.org/10.7546/ijba.2019.23.1.61-70","url":null,"abstract":"Each ECG analysis begins with the detection of the QRS complex, which is the most distinguishable wave for initial investigation. Long ago we published an algorithm for ventricular beats (VB) detection in single ECG lead. The classification of normal QRS complexes is based on the slope, the amplitude and the width of the ECG waves. Other criteria recognize ventricular ectopic beats (EB) by presence of biphasic beats and separate premature EB from the already detected QRS complexes. The aim of this paper is to place the MATLAB program of our algorithm at disposal to the readers (supplementary MATLAB codes) looking forward to more successful ECG investigations.","PeriodicalId":38867,"journal":{"name":"International Journal Bioautomation","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44739939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-03-01DOI: 10.7546/IJBA.2019.23.1.87-96
Xiaoke Zhang, Linyan Xue, Kang Yin, Tianyi Wang, Kun Yang
This paper aims to eliminate the hardening artifacts in computed tomography (CT) images caused by the polychromatic X-ray spectrum. To this end, a polynomial fitting correction method using non-liner segmentation method was developed through projection space optimization for single medium (water) and the mixed media (water-bone), and verified through simulation and phantom experiments. Unlike the traditional image space optimization strategies, the proposed method has low computing load and few noises, and only requires a one-off image reconstruction to remove the hardening artifacts. The experimental results show that the proposed method can remove CT hardening artifacts and improve the accuracy of image reconstruction, indicating that the project space-based correction method based on non-liner segmentation method can effectively eliminate artifacts and restore the true CT values.
{"title":"Computed Tomography Beam Hardening Correction Based on Non-linear Segmentation","authors":"Xiaoke Zhang, Linyan Xue, Kang Yin, Tianyi Wang, Kun Yang","doi":"10.7546/IJBA.2019.23.1.87-96","DOIUrl":"https://doi.org/10.7546/IJBA.2019.23.1.87-96","url":null,"abstract":"This paper aims to eliminate the hardening artifacts in computed tomography (CT) images caused by the polychromatic X-ray spectrum. To this end, a polynomial fitting correction method using non-liner segmentation method was developed through projection space optimization for single medium (water) and the mixed media (water-bone), and verified through simulation and phantom experiments. Unlike the traditional image space optimization strategies, the proposed method has low computing load and few noises, and only requires a one-off image reconstruction to remove the hardening artifacts. The experimental results show that the proposed method can remove CT hardening artifacts and improve the accuracy of image reconstruction, indicating that the project space-based correction method based on non-liner segmentation method can effectively eliminate artifacts and restore the true CT values.","PeriodicalId":38867,"journal":{"name":"International Journal Bioautomation","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45918702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-03-01DOI: 10.7546/IJBA.2019.23.1.105-116
Yanfeng Liu, Yongquan Liang
There are many operon prediction models, but few methods can be applied to the operon prediction of new sequencing species effectively. In this paper, an operon prediction model based on Markov clustering algorithm is proposed. The model uses some generic attribute information of genomes and graph clustering algorithm instead of classifier to predict operon. Similarly to most operon prediction models, E. coli K12 and B. subtilis str. 168 were used to assess the prediction capability of the proposed model, the experiment results show that the proposed model has better capability of operon prediction than some other classical operon prediction methods.
{"title":"Operon Prediction Model Based on Markov Clustering Algorithm","authors":"Yanfeng Liu, Yongquan Liang","doi":"10.7546/IJBA.2019.23.1.105-116","DOIUrl":"https://doi.org/10.7546/IJBA.2019.23.1.105-116","url":null,"abstract":"There are many operon prediction models, but few methods can be applied to the operon prediction of new sequencing species effectively. In this paper, an operon prediction model based on Markov clustering algorithm is proposed. The model uses some generic attribute information of genomes and graph clustering algorithm instead of classifier to predict operon. Similarly to most operon prediction models, E. coli K12 and B. subtilis str. 168 were used to assess the prediction capability of the proposed model, the experiment results show that the proposed model has better capability of operon prediction than some other classical operon prediction methods.","PeriodicalId":38867,"journal":{"name":"International Journal Bioautomation","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48846943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-03-01DOI: 10.7546/IJBA.2019.23.1.41-50
M. Staneva, V. Grigorova
The study was aimed at estimating the semantic priming effect for wide attention focus on subjects response time (RT) in a decision-making visuomotor hand movement task (VMHT) performed in traffic scenarios for non-professional driver’s license tests. The priming was based on modified scrambled sentence task. Traffic scenarios were displayed either on whole screen or within the central 25% of the screen. VMHT was presented: 1) immediately after priming; 2) after primed in the same way adaptation of reactive visual saccade; 3) without priming and saccade adaptation. Thirty young and thirty older subjects took part in the study as they were divided equally into three groups with respect to the three conditions: 1) YP and OP (a group where the traffic test is performed before the sacccade adaptation); 2) YS and OS (after the saccade adaptation); 3) YC and OC (control group). The outcomes established that RTs of both YP and OP groups are higher while RTs of YS and OS groups are lower in comparison with the control groups. RTs of all older groups were significantly longer than those of the younger groups. Longer RTs were found with respect to large pictures than to small pictures. These results suggest that semantic priming has a rather negative effect on decision-making VMHT performance because priming with scrambled sentences also involves a decision-making process. Therefore, they both need similar cognitive resources of which probably VMHT is deprived by the preceding priming and as consequence its perceptual realization is delayed. The study suggests that priming and visuomotor performance are related and the effect of the former on the latter depends on which cognitive resources they need.
{"title":"Effect of Semantic Priming for Wide Attention Focus on Visuomotor Decision-making Task in Young and Older Non-professional Drivers","authors":"M. Staneva, V. Grigorova","doi":"10.7546/IJBA.2019.23.1.41-50","DOIUrl":"https://doi.org/10.7546/IJBA.2019.23.1.41-50","url":null,"abstract":"The study was aimed at estimating the semantic priming effect for wide attention focus on subjects response time (RT) in a decision-making visuomotor hand movement task (VMHT) performed in traffic scenarios for non-professional driver’s license tests. The priming was based on modified scrambled sentence task. Traffic scenarios were displayed either on whole screen or within the central 25% of the screen. VMHT was presented: 1) immediately after priming; 2) after primed in the same way adaptation of reactive visual saccade; 3) without priming and saccade adaptation. Thirty young and thirty older subjects took part in the study as they were divided equally into three groups with respect to the three conditions: 1) YP and OP (a group where the traffic test is performed before the sacccade adaptation); 2) YS and OS (after the saccade adaptation); 3) YC and OC (control group). The outcomes established that RTs of both YP and OP groups are higher while RTs of YS and OS groups are lower in comparison with the control groups. RTs of all older groups were significantly longer than those of the younger groups. Longer RTs were found with respect to large pictures than to small pictures. These results suggest that semantic priming has a rather negative effect on decision-making VMHT performance because priming with scrambled sentences also involves a decision-making process. Therefore, they both need similar cognitive resources of which probably VMHT is deprived by the preceding priming and as consequence its perceptual realization is delayed. The study suggests that priming and visuomotor performance are related and the effect of the former on the latter depends on which cognitive resources they need.","PeriodicalId":38867,"journal":{"name":"International Journal Bioautomation","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42586170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-12-01DOI: 10.7546/ijba.2018.22.4.337-348
H. Yin
In order to explore the application of graphene field effect transistor (FET) nucleic acid biosensor, the sensitivity and selectivity of nano FET biosensor detection are improved by the large physical surface ratio, high electron mobility, excellent thermo conductivity and high mechanical strength. The nano-material graphene is applied to the field effect transistor biosensor, and the FET biosensor based on graphene is constructed. In addition, target molecules with specific probes are immobilized on the surface of graphene. The purpose of detecting nucleic acid molecules with high sensitivity and high selectivity can be achieved by detecting the change of electrical signals before and after hybridization and using nucleic acid – nucleic acid molecules hybridization. At the same time, the DNA biosensor can be reused. The reduced graphene oxide (R-GO) field effect transistor DNA biosensor constructed has high sensitivity, high selectivity and reusability. The research results showed that it has a potential application prospect in human motion measurement as a detection tool. To sum up, graphene FET nucleic acid biosensor is suitable for being used in human motion measurement.
{"title":"Application of Graphene FET Nucleic Acid Biosensor in Human Motion Measurement","authors":"H. Yin","doi":"10.7546/ijba.2018.22.4.337-348","DOIUrl":"https://doi.org/10.7546/ijba.2018.22.4.337-348","url":null,"abstract":"In order to explore the application of graphene field effect transistor (FET) nucleic acid biosensor, the sensitivity and selectivity of nano FET biosensor detection are improved by the large physical surface ratio, high electron mobility, excellent thermo conductivity and high mechanical strength. The nano-material graphene is applied to the field effect transistor biosensor, and the FET biosensor based on graphene is constructed. In addition, target molecules with specific probes are immobilized on the surface of graphene. The purpose of detecting nucleic acid molecules with high sensitivity and high selectivity can be achieved by detecting the change of electrical signals before and after hybridization and using nucleic acid – nucleic acid molecules hybridization. At the same time, the DNA biosensor can be reused. The reduced graphene oxide (R-GO) field effect transistor DNA biosensor constructed has high sensitivity, high selectivity and reusability. The research results showed that it has a potential application prospect in human motion measurement as a detection tool. To sum up, graphene FET nucleic acid biosensor is suitable for being used in human motion measurement.","PeriodicalId":38867,"journal":{"name":"International Journal Bioautomation","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45231573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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