Pub Date : 2020-01-01DOI: 10.5336/dermato.2019-65660
Rafet Özbey, D. Turkmen
often small and skin colored, and located anywhere on the body surface area despite mostly seen in the axillary and neck. Acrochordons are also known by names such as fibroepithelial polyp, skin tags, soft fibroma. It is one of the most common skin lesions.1 They are stalked lesions which are often seen in the neck and armpit.2 Several studies have revealed an association of acrochordons with conditions such as obesity, diabetes mellitus, atherogenic lipid profile, acromegaly and Crohn’s disease.3 Acrochordons are generally more common in overweight individuals. It has been suggested that hyperinsulinemia and increased leptin levels may play a role in the development of acrochordon in overweight individuals.4 It has been reported that acrochordons are closely associated with conditions leading to hyperinsulinemia such as metabolic syndrome (MetS) and may play a role in the early diagnosis of MetS.3,5 Acanthosis nigricans is common in obese and diabetic patients, therefore it is likely to be associated with acrocordon.6
{"title":"A Rare Case: A Giant Acrochordon and Skin Ulcer Due to the Traction of Acrochordon","authors":"Rafet Özbey, D. Turkmen","doi":"10.5336/dermato.2019-65660","DOIUrl":"https://doi.org/10.5336/dermato.2019-65660","url":null,"abstract":"often small and skin colored, and located anywhere on the body surface area despite mostly seen in the axillary and neck. Acrochordons are also known by names such as fibroepithelial polyp, skin tags, soft fibroma. It is one of the most common skin lesions.1 They are stalked lesions which are often seen in the neck and armpit.2 Several studies have revealed an association of acrochordons with conditions such as obesity, diabetes mellitus, atherogenic lipid profile, acromegaly and Crohn’s disease.3 Acrochordons are generally more common in overweight individuals. It has been suggested that hyperinsulinemia and increased leptin levels may play a role in the development of acrochordon in overweight individuals.4 It has been reported that acrochordons are closely associated with conditions leading to hyperinsulinemia such as metabolic syndrome (MetS) and may play a role in the early diagnosis of MetS.3,5 Acanthosis nigricans is common in obese and diabetic patients, therefore it is likely to be associated with acrocordon.6","PeriodicalId":39132,"journal":{"name":"Turkiye Klinikleri Dermatoloji","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70754001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.5336/dermato.2019-70450
Nalan Saraç, M. Bakırtaş
{"title":"Unilateral Lichen Aureus: A Child Case Report with Dermoscopic Features","authors":"Nalan Saraç, M. Bakırtaş","doi":"10.5336/dermato.2019-70450","DOIUrl":"https://doi.org/10.5336/dermato.2019-70450","url":null,"abstract":"","PeriodicalId":39132,"journal":{"name":"Turkiye Klinikleri Dermatoloji","volume":"30 1","pages":"120-123"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70754811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.5336/dermato.2020-75109
Ezgi Aktaş Karabay, E. Karabay, Ö. Demirel, N. Karşıyakalı
Objective: Rosacea, a chronic inflammatory skin di- sease, is known to be associated with various systemic disorders. Ho-wever, limited data are available on the association between rosacea and renal diseases. The objective of this study was to evaluate serum creatinine, cystatin C and neutrophil gelatinase-associated lipocalin (NGAL) levels in patients with rosacea without any systemic diseases. Material and Methods: A prospective, case-control study was planned to investigate the relationship between rosacea and renal involvement by evaluating serum creatinine, cystatin C and NGAL levels. Results: A total of 38 patients with rosacea and 45 healthy controls were included. Statistically significant differences in serum creatinine and cysta- tin C levels were noted between the patient and control groups (respectively p=0.012, p<0.001). No statistically significant difference was shown in the values of NGAL between the two groups (p=0.235). A positive correlation was noted between serum creatinine and serum cystatin C levels (r=0.434; p<0.001). The serum levels of cystatin C were positively correlated with disease duration (r=0.511, p<0.001). Conclusion: Serum creatinine and cystatin C levels may provide early detection of renal dysfunction in rosacea.
目的:酒渣鼻是一种慢性炎症性皮肤病，与多种全身疾病有关。然而，关于酒渣鼻和肾脏疾病之间关系的数据有限。本研究的目的是评估无任何系统性疾病的酒渣鼻患者血清肌酐、胱抑素C和中性粒细胞明胶酶相关脂钙蛋白(NGAL)水平。材料与方法:一项前瞻性的病例对照研究计划通过评估血清肌酐、胱抑素C和NGAL水平来探讨酒渣鼻与肾脏受累的关系。结果:共纳入38例酒渣鼻患者和45例健康对照。患者与对照组血清肌酐、cysta- tin C水平差异有统计学意义(p=0.012, p<0.001)。两组患者NGAL值差异无统计学意义(p=0.235)。血清肌酐与血清胱抑素C水平呈正相关(r=0.434;p < 0.001)。血清胱抑素C水平与病程呈正相关(r=0.511, p<0.001)。结论:血清肌酐和胱抑素C水平可作为酒渣鼻肾功能不全的早期检测指标。
{"title":"Assessment of Serum Creatinine, Cystatin C and Neutrophil Gelatinase-associated Lipocalin Levels in Rosacea: A Case-Control Study","authors":"Ezgi Aktaş Karabay, E. Karabay, Ö. Demirel, N. Karşıyakalı","doi":"10.5336/dermato.2020-75109","DOIUrl":"https://doi.org/10.5336/dermato.2020-75109","url":null,"abstract":"Objective: Rosacea, a chronic inflammatory skin di- sease, is known to be associated with various systemic disorders. Ho-wever, limited data are available on the association between rosacea and renal diseases. The objective of this study was to evaluate serum creatinine, cystatin C and neutrophil gelatinase-associated lipocalin (NGAL) levels in patients with rosacea without any systemic diseases. Material and Methods: A prospective, case-control study was planned to investigate the relationship between rosacea and renal involvement by evaluating serum creatinine, cystatin C and NGAL levels. Results: A total of 38 patients with rosacea and 45 healthy controls were included. Statistically significant differences in serum creatinine and cysta- tin C levels were noted between the patient and control groups (respectively p=0.012, p<0.001). No statistically significant difference was shown in the values of NGAL between the two groups (p=0.235). A positive correlation was noted between serum creatinine and serum cystatin C levels (r=0.434; p<0.001). The serum levels of cystatin C were positively correlated with disease duration (r=0.511, p<0.001). Conclusion: Serum creatinine and cystatin C levels may provide early detection of renal dysfunction in rosacea.","PeriodicalId":39132,"journal":{"name":"Turkiye Klinikleri Dermatoloji","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70756033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.5336/dermato.2020-79842
Tugba Gür, S. Erdoğan, Ezgi Özkur, A. Aksu, C. Leblebici, M. Gürel
{"title":"Lipidized Dermatofibroma: The Clinical and Demographic Characteristics of Twelve Cases","authors":"Tugba Gür, S. Erdoğan, Ezgi Özkur, A. Aksu, C. Leblebici, M. Gürel","doi":"10.5336/dermato.2020-79842","DOIUrl":"https://doi.org/10.5336/dermato.2020-79842","url":null,"abstract":"","PeriodicalId":39132,"journal":{"name":"Turkiye Klinikleri Dermatoloji","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70756593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.5336/dermato.2020-77786
Funda Kemeriz, S. Tuncer, Burcu Tuğrul
{"title":"Evaluation of 25-HydroxyVitamin D Levels in Patients with Chronic Telogen Effluvium: A Retrospective Analysis of 291 Cases","authors":"Funda Kemeriz, S. Tuncer, Burcu Tuğrul","doi":"10.5336/dermato.2020-77786","DOIUrl":"https://doi.org/10.5336/dermato.2020-77786","url":null,"abstract":"","PeriodicalId":39132,"journal":{"name":"Turkiye Klinikleri Dermatoloji","volume":"30 1","pages":"69-73"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70756784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.5336/DERMATO.2019-65810
M. Yalçın, Celali Kurt, H. Güngör
ABS TRACT Drug reaction with eosinophilia and systemic symptom (DRESS) is a life threatening adverse drug reaction. A 58-year-old female patient presented to our hospital with nausea and vomiting 2 weeks after elective coronary artery bypass grafting (CABG). She had used metoprololol, asetilsalycilic asit and furosemide after the oper- ation. Blood tests showed neutropenia, low eosinophil levels, elevated liver biomarkers. Our case had fever, a morbilliform rash, bone mar- row failure and hepatitis. Clinical (fever, exanthema, facial oedema) and laboratory (pansitopenia with liver and pulmonary involvement) findings raised the suspicion of DRESS and the patient was started on 1 mg/kg intravenous (IV) prednisone daily and IV immunoglobulin (IVIG) at 2 g/kg. She died on the the seventh ICU day. DRESS syndrome is a fatal drug hypersensitivity reaction with cutaneous and systemic involvements. Multidisciplinary care is important for a suc-cessful treatment.
{"title":"Fatal DRESS Syndrome Without Eosinophilia After Coronary Artery Bypass Grafting","authors":"M. Yalçın, Celali Kurt, H. Güngör","doi":"10.5336/DERMATO.2019-65810","DOIUrl":"https://doi.org/10.5336/DERMATO.2019-65810","url":null,"abstract":"ABS TRACT Drug reaction with eosinophilia and systemic symptom (DRESS) is a life threatening adverse drug reaction. A 58-year-old female patient presented to our hospital with nausea and vomiting 2 weeks after elective coronary artery bypass grafting (CABG). She had used metoprololol, asetilsalycilic asit and furosemide after the oper- ation. Blood tests showed neutropenia, low eosinophil levels, elevated liver biomarkers. Our case had fever, a morbilliform rash, bone mar- row failure and hepatitis. Clinical (fever, exanthema, facial oedema) and laboratory (pansitopenia with liver and pulmonary involvement) findings raised the suspicion of DRESS and the patient was started on 1 mg/kg intravenous (IV) prednisone daily and IV immunoglobulin (IVIG) at 2 g/kg. She died on the the seventh ICU day. DRESS syndrome is a fatal drug hypersensitivity reaction with cutaneous and systemic involvements. Multidisciplinary care is important for a suc-cessful treatment.","PeriodicalId":39132,"journal":{"name":"Turkiye Klinikleri Dermatoloji","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70754012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.5336/dermato.2020-74904
H. Akca, Kevser Tuncer Kara
inhibition. the between the clinical severity of acne and quality of life. Material and Methods: A total of 100 patients diagnosed with acne vulgaris were included in the study. The patients' age, gender, duration of the disease, and local and systemic treatments that were received be-fore and acne severity scores were recorded. Acne quality of life ques- tionnaire (Acne-QoL) was applied and total scores were determined. Results: The average of the Acne-QoL scores was 16±5.22, and there was no statistically significant difference between the mild-moderate and severe acne groups in terms of quality of life (p>0.05). Conclu- sion: Although acne affects the physical appearance, it may also greatly affect the quality of life of patients in mild and moderate clinical types.
{"title":"The Correlation Between Clinical Type of Acne and Quality of Life in Acne Vulgaris Patients","authors":"H. Akca, Kevser Tuncer Kara","doi":"10.5336/dermato.2020-74904","DOIUrl":"https://doi.org/10.5336/dermato.2020-74904","url":null,"abstract":"inhibition. the between the clinical severity of acne and quality of life. Material and Methods: A total of 100 patients diagnosed with acne vulgaris were included in the study. The patients' age, gender, duration of the disease, and local and systemic treatments that were received be-fore and acne severity scores were recorded. Acne quality of life ques- tionnaire (Acne-QoL) was applied and total scores were determined. Results: The average of the Acne-QoL scores was 16±5.22, and there was no statistically significant difference between the mild-moderate and severe acne groups in terms of quality of life (p>0.05). Conclu- sion: Although acne affects the physical appearance, it may also greatly affect the quality of life of patients in mild and moderate clinical types.","PeriodicalId":39132,"journal":{"name":"Turkiye Klinikleri Dermatoloji","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70756280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.5336/dermato.2020-79035
R. Güneş, S. Çakmak, A. Yorulmaz
{"title":"Mucocutaneous Manifestation of HIV and the Correlation with CD4 Count and Viral Load: A Prospective Study from Turkey","authors":"R. Güneş, S. Çakmak, A. Yorulmaz","doi":"10.5336/dermato.2020-79035","DOIUrl":"https://doi.org/10.5336/dermato.2020-79035","url":null,"abstract":"","PeriodicalId":39132,"journal":{"name":"Turkiye Klinikleri Dermatoloji","volume":"30 1","pages":"88-94"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70756510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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