Pub Date : 2021-12-01DOI: 10.4067/s0717-92272021000400361
Gonzalo Klaassen P., Enrique Werlinger E., Loreto Contreras E., A. González B., Aldo Vera C., Sergio Juica A., Mario Fuentealba S.
{"title":"Calidad de Vida en Demencia Alzheimer: un nuevo desafío","authors":"Gonzalo Klaassen P., Enrique Werlinger E., Loreto Contreras E., A. González B., Aldo Vera C., Sergio Juica A., Mario Fuentealba S.","doi":"10.4067/s0717-92272021000400361","DOIUrl":"https://doi.org/10.4067/s0717-92272021000400361","url":null,"abstract":"","PeriodicalId":39300,"journal":{"name":"Revista Chilena de Neuro-Psiquiatria","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49602624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-01DOI: 10.4067/s0717-92272021000400308
Rosa Behar, F. D. L. Barra
Background: A history of childhood sexual abuse (SA) or adolescence in eating disorders (ED) is documented in clinical experience and in the literature. However, the complex relationships between both conditions have not been systematized. Objective: To describe the clinical and neurobiological relationship between SA and ED. Method: The specialized literature in texts and articles included in Medline/PubMed, SciELO was thoroughly analysed. Central concepts were outlined and information was written seeking didactic cohesion, including an illustrative clinical case. Results: Although SA is a nonspecific factor for the development of mental disorders, it constitutes a significant predisposing, triggering and perpetuating phenomenon for the emergence of ED, mainly bulimia nervosa. Risk, mediator, predictor, protective and resilience factors are described. Both specific conditions show analogous neurobiological and clinical correlates (core symptoms and adaptive functions). Similar dysfunctions exist in reward and emotional regulation circuits, with limited structural disturbances in prefrontal areas. Conclusions: There is strong evidence of the coexistence of SA in ED. However, it is necessary to develop research models that truly integrate genetic, hormonal, neurotransmitter, personality and sociocultural risk processes. integren realmente los procesos genéticos, hormonales, neurotransmisores, de personalidad y socioculturales de riesgo. Palabras clave: Abuso Infantil, Adolescente, Sexual, Trastornos de la Alimentación y de la Ingesta Alimentaria
背景:临床经验和文献中记录了儿童期性虐待(SA)或青春期饮食失调(ED)的病史。然而,这两种情况之间的复杂关系尚未系统化。目的:描述SA和ED之间的临床和神经生物学关系。方法:对Medline/PubMed,SciELO中的专门文献和文章进行全面分析。概述了中心概念,并编写了寻求教学凝聚力的信息,包括一个说明性的临床案例。结果:尽管SA是精神障碍发展的非特异性因素,但它构成了ED(主要是神经性贪食症)出现的重要诱因、触发和持续现象。介绍了风险、中介因素、预测因素、保护因素和恢复力因素。这两种特殊情况都显示出类似的神经生物学和临床相关性(核心症状和适应功能)。类似的功能障碍也存在于奖赏和情绪调节回路中,前额叶区域的结构紊乱有限。结论:有强有力的证据表明SA在ED中共存。然而,有必要开发真正整合遗传、激素、神经递质、个性和社会文化风险过程的研究模型。基因、激素、神经传递、个性和社会文化过程的整合。Palabras clave:Abuso Infantil,青少年,性,Trastornos de la Alimentación and de la Ingesta Alimentaria
{"title":"Abuso sexual infantil y adolescente y su relación con trastornos alimentarios","authors":"Rosa Behar, F. D. L. Barra","doi":"10.4067/s0717-92272021000400308","DOIUrl":"https://doi.org/10.4067/s0717-92272021000400308","url":null,"abstract":"Background: A history of childhood sexual abuse (SA) or adolescence in eating disorders (ED) is documented in clinical experience and in the literature. However, the complex relationships between both conditions have not been systematized. Objective: To describe the clinical and neurobiological relationship between SA and ED. Method: The specialized literature in texts and articles included in Medline/PubMed, SciELO was thoroughly analysed. Central concepts were outlined and information was written seeking didactic cohesion, including an illustrative clinical case. Results: Although SA is a nonspecific factor for the development of mental disorders, it constitutes a significant predisposing, triggering and perpetuating phenomenon for the emergence of ED, mainly bulimia nervosa. Risk, mediator, predictor, protective and resilience factors are described. Both specific conditions show analogous neurobiological and clinical correlates (core symptoms and adaptive functions). Similar dysfunctions exist in reward and emotional regulation circuits, with limited structural disturbances in prefrontal areas. Conclusions: There is strong evidence of the coexistence of SA in ED. However, it is necessary to develop research models that truly integrate genetic, hormonal, neurotransmitter, personality and sociocultural risk processes. integren realmente los procesos genéticos, hormonales, neurotransmisores, de personalidad y socioculturales de riesgo. Palabras clave: Abuso Infantil, Adolescente, Sexual, Trastornos de la Alimentación y de la Ingesta Alimentaria","PeriodicalId":39300,"journal":{"name":"Revista Chilena de Neuro-Psiquiatria","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49174073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-01DOI: 10.4067/s0717-92272021000400280
C. R. Mejía, Cecilia Fernandez-Ledezma, Eddy Cossio-Andia
Introduction: Cognitive impairment is an important pathology among the Aged, but few studies evaluate populations at an important geographical height. Objectives: To characterize and find the factors associated with cognitive deterioration in urban and rural populations of medium geographic height. Methodology: Analytical cross-sectional study, cognitive impairment was evaluated with the Pfeiffer Test (Cronbach's Alpha: 0.69), its results were combined versus three socio-educational variables and four comorbidities; analytical statistics were obtained. Results: Of the 400 older adults, 26.5% (106) had no cognitive impairment, 47.5% (190) had mild impairment, 25.5% (102) moderate and 0.5% (2) severe; 60% were women, the median age was 66 years (interquartile range: 63-69 years), 67% lived in rural areas. In the multivariate analysis it was found that there was more moderate / severe cognitive impairment at older age (RPa: 1.05; 95% CI: 1.02-1.08; p <0.001), among those with diabetes (RPa: 1 , 23; 95% CI: 1.17-1.29; p <0.001), arterial hypertension (RPa: 1.47; 95% CI: 1.33-1.61; p <0.001), chronic kidney disease (RPa: 2.21, 95% CI 2.01-2.43, p <0.001) and heart failure (RPa: 2.25, 95% CI 1.92-2.64, p <0.001); On the other hand, those with a university degree had less cognitive deterioration (RPa: 0.89, 95% CI: 0.22-0.65, p <0.001); adjusted for sex and place of residence. Conclusion: Important associations of cognitive deterioration were found in an older adult population residing between 2500-3900 msnm, these results are important as they are not a highly studied population; therefore, these data should be taken for diagnosis and treatment.
{"title":"Deterioro cognitivo en poblaciones urbanas y rurales de la mediana altura geográfica en Bolivia: Prevalencia y factores asociados","authors":"C. R. Mejía, Cecilia Fernandez-Ledezma, Eddy Cossio-Andia","doi":"10.4067/s0717-92272021000400280","DOIUrl":"https://doi.org/10.4067/s0717-92272021000400280","url":null,"abstract":"Introduction: Cognitive impairment is an important pathology among the Aged, but few studies evaluate populations at an important geographical height. Objectives: To characterize and find the factors associated with cognitive deterioration in urban and rural populations of medium geographic height. Methodology: Analytical cross-sectional study, cognitive impairment was evaluated with the Pfeiffer Test (Cronbach's Alpha: 0.69), its results were combined versus three socio-educational variables and four comorbidities; analytical statistics were obtained. Results: Of the 400 older adults, 26.5% (106) had no cognitive impairment, 47.5% (190) had mild impairment, 25.5% (102) moderate and 0.5% (2) severe; 60% were women, the median age was 66 years (interquartile range: 63-69 years), 67% lived in rural areas. In the multivariate analysis it was found that there was more moderate / severe cognitive impairment at older age (RPa: 1.05; 95% CI: 1.02-1.08; p <0.001), among those with diabetes (RPa: 1 , 23; 95% CI: 1.17-1.29; p <0.001), arterial hypertension (RPa: 1.47; 95% CI: 1.33-1.61; p <0.001), chronic kidney disease (RPa: 2.21, 95% CI 2.01-2.43, p <0.001) and heart failure (RPa: 2.25, 95% CI 1.92-2.64, p <0.001); On the other hand, those with a university degree had less cognitive deterioration (RPa: 0.89, 95% CI: 0.22-0.65, p <0.001); adjusted for sex and place of residence. Conclusion: Important associations of cognitive deterioration were found in an older adult population residing between 2500-3900 msnm, these results are important as they are not a highly studied population; therefore, these data should be taken for diagnosis and treatment.","PeriodicalId":39300,"journal":{"name":"Revista Chilena de Neuro-Psiquiatria","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42727012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-01DOI: 10.4067/s0717-92272021000400343
Ignacio Olivares R., Alicia Figueroa B.
Introduction: The need for early intervention in psychosis has led to the search for useful biomarkers in its prediction, where the analysis of spoken language stands out for its easy obtaining and low economic cost. In this systematic review, we analyze the main speech disturbances in patients at ultra-high risk for psychosis (UHR), evaluating their prevalence and their relationship with transition to psychosis. Methods: A search was carried out in PubMed and Embase databases for studies in English or Spanish, as well as the reference lists of the articles found. Results: Of 140 articles identified, 15 were included. The variables of the language analyzed were Linguistic Cohesion, Semantic Coherence, Syntactic Complexity, Metaphorical Production, Emotional Prosody and Formal Thought Disorder (TFP). The prevalence found ranged between 21% and 85% for disturbances included within the TFP, with no prevalence measures for the rest of the variables. The global accuracy for UHR transition to psychosis ranged from 70% to 100% across studies. Conclusion: There is a wide range of speech disorders in UHR patients, where the TFP is the most studied one. The prevalence of these alterations seems to be high, especially with regard to TFP. The analysis of those speech alterations in UHR patients appears as an excellent tool to predict transition to psychosis, particularly through interview transcription and the use of Artificial Intelligence.
{"title":"Análisis de alteraciones del discurso en estados mentales de alto riesgo de psicosis (EMAR): una revisión sistemática.","authors":"Ignacio Olivares R., Alicia Figueroa B.","doi":"10.4067/s0717-92272021000400343","DOIUrl":"https://doi.org/10.4067/s0717-92272021000400343","url":null,"abstract":"Introduction: The need for early intervention in psychosis has led to the search for useful biomarkers in its prediction, where the analysis of spoken language stands out for its easy obtaining and low economic cost. In this systematic review, we analyze the main speech disturbances in patients at ultra-high risk for psychosis (UHR), evaluating their prevalence and their relationship with transition to psychosis. Methods: A search was carried out in PubMed and Embase databases for studies in English or Spanish, as well as the reference lists of the articles found. Results: Of 140 articles identified, 15 were included. The variables of the language analyzed were Linguistic Cohesion, Semantic Coherence, Syntactic Complexity, Metaphorical Production, Emotional Prosody and Formal Thought Disorder (TFP). The prevalence found ranged between 21% and 85% for disturbances included within the TFP, with no prevalence measures for the rest of the variables. The global accuracy for UHR transition to psychosis ranged from 70% to 100% across studies. Conclusion: There is a wide range of speech disorders in UHR patients, where the TFP is the most studied one. The prevalence of these alterations seems to be high, especially with regard to TFP. The analysis of those speech alterations in UHR patients appears as an excellent tool to predict transition to psychosis, particularly through interview transcription and the use of Artificial Intelligence.","PeriodicalId":39300,"journal":{"name":"Revista Chilena de Neuro-Psiquiatria","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45040413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-01DOI: 10.4067/s0717-92272021000400302
Felipe Vergara T., Jennifer Green M., Antonia Cooper S.
Introduction: Unipolar mania (UM) is a disorder that behaves differently from bipolar-I disorder (BP-I), however, it is not considered an independent entity by current diagnostic manuals, but rather included within the diagnosis of BP-I. Case report: A 21-year-old man presented a 3-month-long episode characterized by exalted mood and mood-congruent psychotic symptoms. The patient denies previous depressive episodes. Treatment with lithium and aripiprazole was established, which was satisfactory, not showing recurrence after 5 years of follow-up. Literature review and discussion: Diagnostic manuals describe that to diagnose BP-I the presence of a major depressive episode is not required, which implies that patients with UM fall into the same diagnostic category as patients with BP-I. Differences between UM and BP-I have been demonstrated in epidemiological, clinical, and genetic studies, therefore, including heterogeneous patients within the same category could hinder the interpretation of studies and limit advances in the knowledge of both disorders. Conclusion: Based on the literature review, it is suggested that UM should be recognized as an independent diagnosis. Despite its low prevalence, by validating it as such, in the future we could have more and better-quality data about this diagnosis. In this way, its distinctive characteristics can be defined more concretely, and therefore improve the clinical approach of these patients.
{"title":"Manía unipolar: un ineludible diagnóstico. Revisión de la literatura a propósito de un caso","authors":"Felipe Vergara T., Jennifer Green M., Antonia Cooper S.","doi":"10.4067/s0717-92272021000400302","DOIUrl":"https://doi.org/10.4067/s0717-92272021000400302","url":null,"abstract":"Introduction: Unipolar mania (UM) is a disorder that behaves differently from bipolar-I disorder (BP-I), however, it is not considered an independent entity by current diagnostic manuals, but rather included within the diagnosis of BP-I. Case report: A 21-year-old man presented a 3-month-long episode characterized by exalted mood and mood-congruent psychotic symptoms. The patient denies previous depressive episodes. Treatment with lithium and aripiprazole was established, which was satisfactory, not showing recurrence after 5 years of follow-up. Literature review and discussion: Diagnostic manuals describe that to diagnose BP-I the presence of a major depressive episode is not required, which implies that patients with UM fall into the same diagnostic category as patients with BP-I. Differences between UM and BP-I have been demonstrated in epidemiological, clinical, and genetic studies, therefore, including heterogeneous patients within the same category could hinder the interpretation of studies and limit advances in the knowledge of both disorders. Conclusion: Based on the literature review, it is suggested that UM should be recognized as an independent diagnosis. Despite its low prevalence, by validating it as such, in the future we could have more and better-quality data about this diagnosis. In this way, its distinctive characteristics can be defined more concretely, and therefore improve the clinical approach of these patients.","PeriodicalId":39300,"journal":{"name":"Revista Chilena de Neuro-Psiquiatria","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46690794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-01DOI: 10.4067/s0717-92272021000400334
Felipe León C, Daniela Silva E, José Villagrán L
{"title":"El rol del placebo frente a los antidepresivos y aportes a la relación médico-paciente","authors":"Felipe León C, Daniela Silva E, José Villagrán L","doi":"10.4067/s0717-92272021000400334","DOIUrl":"https://doi.org/10.4067/s0717-92272021000400334","url":null,"abstract":"","PeriodicalId":39300,"journal":{"name":"Revista Chilena de Neuro-Psiquiatria","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49188834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-01DOI: 10.4067/s0717-92272021000400321
Francisco Rojas Z, V. Venegas S., Cecilia Okuma P, O. Koller C., Sonia Ponce de Leon M, Carmen Olbrich G, Mauro Medeiros F
{"title":"Tratamiento quirúrgico de la epilepsia asociada a tumores neuroepiteliales de bajo grado.","authors":"Francisco Rojas Z, V. Venegas S., Cecilia Okuma P, O. Koller C., Sonia Ponce de Leon M, Carmen Olbrich G, Mauro Medeiros F","doi":"10.4067/s0717-92272021000400321","DOIUrl":"https://doi.org/10.4067/s0717-92272021000400321","url":null,"abstract":"","PeriodicalId":39300,"journal":{"name":"Revista Chilena de Neuro-Psiquiatria","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46309739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-01DOI: 10.4067/s0717-92272021000400375
Francisca Iglesias C, J. Castellón V, Grecia Castro C, Catalina Silva H
{"title":"Carcinomatosis meníngea secundaria a melanoma metastásico – reporte de un caso","authors":"Francisca Iglesias C, J. Castellón V, Grecia Castro C, Catalina Silva H","doi":"10.4067/s0717-92272021000400375","DOIUrl":"https://doi.org/10.4067/s0717-92272021000400375","url":null,"abstract":"","PeriodicalId":39300,"journal":{"name":"Revista Chilena de Neuro-Psiquiatria","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42882296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-01DOI: 10.4067/s0717-92272021000400368
F. Acevedo P., Carolina Delgado Derio, G. Farías
In the course of dementia, the advanced stage is characterized by severe cognitive and physical impairment, defining it as a stage that includes deep memory deficits, minimal verbal skills, inability to walk independently, need of assistance to perform any basic daily life activity and urinary and fecal incontinence. The aim of this report is to describe a case of a 89-year-old woman with Advanced Dementia who goes to neurological control in the company of her family, who request information on how to improve the quality of life at this stage. We describe a proposal of palliative care approach, specifically the active therapeutic conception, as a guide that allows to observe the person not only from the good dying, but also from the incorporation of a proactive attitude in function of well-being. This approach allows to facilitate pleasurable experiences, defined within the framework of Nonpharmacological intervention, which have shown important benefits in people with advanced dementia in the last decade, allowing the identification of intervention strategies in this stage of the disease.
{"title":"Estrategias no farmacológicas en personas con Demencia Avanzada: reporte de un caso.","authors":"F. Acevedo P., Carolina Delgado Derio, G. Farías","doi":"10.4067/s0717-92272021000400368","DOIUrl":"https://doi.org/10.4067/s0717-92272021000400368","url":null,"abstract":"In the course of dementia, the advanced stage is characterized by severe cognitive and physical impairment, defining it as a stage that includes deep memory deficits, minimal verbal skills, inability to walk independently, need of assistance to perform any basic daily life activity and urinary and fecal incontinence. The aim of this report is to describe a case of a 89-year-old woman with Advanced Dementia who goes to neurological control in the company of her family, who request information on how to improve the quality of life at this stage. We describe a proposal of palliative care approach, specifically the active therapeutic conception, as a guide that allows to observe the person not only from the good dying, but also from the incorporation of a proactive attitude in function of well-being. This approach allows to facilitate pleasurable experiences, defined within the framework of Nonpharmacological intervention, which have shown important benefits in people with advanced dementia in the last decade, allowing the identification of intervention strategies in this stage of the disease.","PeriodicalId":39300,"journal":{"name":"Revista Chilena de Neuro-Psiquiatria","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43103311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Habilidades de la Terapia Dialéctica Conductual en el contexto de la pandemia por COVID-19.","authors":"Joshep Revilla Z., Lesly Vargas B., Kalet Rojas M., Edson Quintana C., Franco Sotelo Q.","doi":"10.4067/s0717-92272021000400379","DOIUrl":"https://doi.org/10.4067/s0717-92272021000400379","url":null,"abstract":"","PeriodicalId":39300,"journal":{"name":"Revista Chilena de Neuro-Psiquiatria","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46610231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}