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Revista Chilena de Neuro-Psiquiatria最新文献

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Calidad de Vida en Demencia Alzheimer: un nuevo desafío 阿尔茨海默氏症痴呆症患者的生活质量:一个新的挑战
Q4 Medicine Pub Date : 2021-12-01 DOI: 10.4067/s0717-92272021000400361
Gonzalo Klaassen P., Enrique Werlinger E., Loreto Contreras E., A. González B., Aldo Vera C., Sergio Juica A., Mario Fuentealba S.
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引用次数: 0
Abuso sexual infantil y adolescente y su relación con trastornos alimentarios 儿童和青少年性虐待及其与饮食失调的关系
Q4 Medicine Pub Date : 2021-12-01 DOI: 10.4067/s0717-92272021000400308
Rosa Behar, F. D. L. Barra
Background: A history of childhood sexual abuse (SA) or adolescence in eating disorders (ED) is documented in clinical experience and in the literature. However, the complex relationships between both conditions have not been systematized. Objective: To describe the clinical and neurobiological relationship between SA and ED. Method: The specialized literature in texts and articles included in Medline/PubMed, SciELO was thoroughly analysed. Central concepts were outlined and information was written seeking didactic cohesion, including an illustrative clinical case. Results: Although SA is a nonspecific factor for the development of mental disorders, it constitutes a significant predisposing, triggering and perpetuating phenomenon for the emergence of ED, mainly bulimia nervosa. Risk, mediator, predictor, protective and resilience factors are described. Both specific conditions show analogous neurobiological and clinical correlates (core symptoms and adaptive functions). Similar dysfunctions exist in reward and emotional regulation circuits, with limited structural disturbances in prefrontal areas. Conclusions: There is strong evidence of the coexistence of SA in ED. However, it is necessary to develop research models that truly integrate genetic, hormonal, neurotransmitter, personality and sociocultural risk processes. integren realmente los procesos genéticos, hormonales, neurotransmisores, de personalidad y socioculturales de riesgo. Palabras clave: Abuso Infantil, Adolescente, Sexual, Trastornos de la Alimentación y de la Ingesta Alimentaria
背景:临床经验和文献中记录了儿童期性虐待(SA)或青春期饮食失调(ED)的病史。然而,这两种情况之间的复杂关系尚未系统化。目的:描述SA和ED之间的临床和神经生物学关系。方法:对Medline/PubMed,SciELO中的专门文献和文章进行全面分析。概述了中心概念,并编写了寻求教学凝聚力的信息,包括一个说明性的临床案例。结果:尽管SA是精神障碍发展的非特异性因素,但它构成了ED(主要是神经性贪食症)出现的重要诱因、触发和持续现象。介绍了风险、中介因素、预测因素、保护因素和恢复力因素。这两种特殊情况都显示出类似的神经生物学和临床相关性(核心症状和适应功能)。类似的功能障碍也存在于奖赏和情绪调节回路中,前额叶区域的结构紊乱有限。结论:有强有力的证据表明SA在ED中共存。然而,有必要开发真正整合遗传、激素、神经递质、个性和社会文化风险过程的研究模型。基因、激素、神经传递、个性和社会文化过程的整合。Palabras clave:Abuso Infantil,青少年,性,Trastornos de la Alimentación and de la Ingesta Alimentaria
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引用次数: 1
Deterioro cognitivo en poblaciones urbanas y rurales de la mediana altura geográfica en Bolivia: Prevalencia y factores asociados 玻利维亚中等地理高度城市和农村人口的认知障碍:患病率和相关因素
Q4 Medicine Pub Date : 2021-12-01 DOI: 10.4067/s0717-92272021000400280
C. R. Mejía, Cecilia Fernandez-Ledezma, Eddy Cossio-Andia
Introduction: Cognitive impairment is an important pathology among the Aged, but few studies evaluate populations at an important geographical height. Objectives: To characterize and find the factors associated with cognitive deterioration in urban and rural populations of medium geographic height. Methodology: Analytical cross-sectional study, cognitive impairment was evaluated with the Pfeiffer Test (Cronbach's Alpha: 0.69), its results were combined versus three socio-educational variables and four comorbidities; analytical statistics were obtained. Results: Of the 400 older adults, 26.5% (106) had no cognitive impairment, 47.5% (190) had mild impairment, 25.5% (102) moderate and 0.5% (2) severe; 60% were women, the median age was 66 years (interquartile range: 63-69 years), 67% lived in rural areas. In the multivariate analysis it was found that there was more moderate / severe cognitive impairment at older age (RPa: 1.05; 95% CI: 1.02-1.08; p <0.001), among those with diabetes (RPa: 1 , 23; 95% CI: 1.17-1.29; p <0.001), arterial hypertension (RPa: 1.47; 95% CI: 1.33-1.61; p <0.001), chronic kidney disease (RPa: 2.21, 95% CI 2.01-2.43, p <0.001) and heart failure (RPa: 2.25, 95% CI 1.92-2.64, p <0.001); On the other hand, those with a university degree had less cognitive deterioration (RPa: 0.89, 95% CI: 0.22-0.65, p <0.001); adjusted for sex and place of residence. Conclusion: Important associations of cognitive deterioration were found in an older adult population residing between 2500-3900 msnm, these results are important as they are not a highly studied population; therefore, these data should be taken for diagnosis and treatment.
引言:认知障碍是老年人的一种重要病理学,但很少有研究评估处于重要地理高度的人群。目的:研究中等地理高度城市和农村人群认知能力下降的相关因素。方法:分析性横断面研究,使用Pfeiffer检验(Cronbach’s Alpha:0.69)评估认知障碍,其结果与三个社会教育变量和四种合并症相结合;获得了分析统计数据。结果:在400名老年人中,26.5%(106)没有认知障碍,47.5%(190)有轻度障碍,25.5%(102)中度和0.5%(2)重度;60%为女性,中位年龄为66岁(四分位间距:63-69岁),67%生活在农村地区。在多变量分析中发现,在患有糖尿病(RPa:1,23;95%CI:1.17-1.29;p<0.001)、动脉高血压(RPa:1.47;95%CI:1.33-1.61;p<0.001),慢性肾脏疾病(RPa:2.21,95%CI 2.01-2.43,p<0.001)和心力衰竭(RPa=2.25,95%CI 1.92-2.64,p<0.001);另一方面,具有大学学历的人认知能力下降较少(RPa:0.89,95%CI:0.22-0.65,p<0.001);根据性别和居住地进行调整。结论:在居住在2500-3900 msnm之间的老年人群中发现了认知退化的重要关联,这些结果很重要,因为他们不是一个高度研究的人群;因此,这些数据应用于诊断和治疗。
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引用次数: 0
Análisis de alteraciones del discurso en estados mentales de alto riesgo de psicosis (EMAR): una revisión sistemática. 精神病高危心理状态下言语障碍的分析:一项系统回顾。
Q4 Medicine Pub Date : 2021-12-01 DOI: 10.4067/s0717-92272021000400343
Ignacio Olivares R., Alicia Figueroa B.
Introduction: The need for early intervention in psychosis has led to the search for useful biomarkers in its prediction, where the analysis of spoken language stands out for its easy obtaining and low economic cost. In this systematic review, we analyze the main speech disturbances in patients at ultra-high risk for psychosis (UHR), evaluating their prevalence and their relationship with transition to psychosis. Methods: A search was carried out in PubMed and Embase databases for studies in English or Spanish, as well as the reference lists of the articles found. Results: Of 140 articles identified, 15 were included. The variables of the language analyzed were Linguistic Cohesion, Semantic Coherence, Syntactic Complexity, Metaphorical Production, Emotional Prosody and Formal Thought Disorder (TFP). The prevalence found ranged between 21% and 85% for disturbances included within the TFP, with no prevalence measures for the rest of the variables. The global accuracy for UHR transition to psychosis ranged from 70% to 100% across studies. Conclusion: There is a wide range of speech disorders in UHR patients, where the TFP is the most studied one. The prevalence of these alterations seems to be high, especially with regard to TFP. The analysis of those speech alterations in UHR patients appears as an excellent tool to predict transition to psychosis, particularly through interview transcription and the use of Artificial Intelligence.
引言:对精神病早期干预的需求导致了在其预测中寻找有用的生物标志物,其中口语分析以其易于获得和低经济成本而突出。在这篇系统综述中,我们分析了超高精神病风险(UHR)患者的主要言语障碍,评估了其患病率及其与向精神病过渡的关系。方法:在PubMed和Embase数据库中搜索英语或西班牙语的研究,以及找到的文章的参考文献列表。结果:在140篇已鉴定的文章中,包括15篇。所分析的语言变量为语言衔接、语义连贯、句法复杂性、隐喻产生、情感韵律和形式思维障碍。TFP中包含的紊乱的患病率在21%至85%之间,其余变量没有患病率测量。在所有研究中,UHR转变为精神病的全球准确率在70%到100%之间。结论:UHR患者存在广泛的言语障碍,其中TFP是研究最多的一种。这些改变的发生率似乎很高,特别是在TFP方面。对UHR患者的这些言语变化的分析似乎是预测向精神病转变的一个很好的工具,特别是通过访谈转录和人工智能的使用。
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引用次数: 0
Manía unipolar: un ineludible diagnóstico. Revisión de la literatura a propósito de un caso 单极狂:不可避免的诊断。关于一个案例的文献综述
Q4 Medicine Pub Date : 2021-12-01 DOI: 10.4067/s0717-92272021000400302
Felipe Vergara T., Jennifer Green M., Antonia Cooper S.
Introduction: Unipolar mania (UM) is a disorder that behaves differently from bipolar-I disorder (BP-I), however, it is not considered an independent entity by current diagnostic manuals, but rather included within the diagnosis of BP-I. Case report: A 21-year-old man presented a 3-month-long episode characterized by exalted mood and mood-congruent psychotic symptoms. The patient denies previous depressive episodes. Treatment with lithium and aripiprazole was established, which was satisfactory, not showing recurrence after 5 years of follow-up. Literature review and discussion: Diagnostic manuals describe that to diagnose BP-I the presence of a major depressive episode is not required, which implies that patients with UM fall into the same diagnostic category as patients with BP-I. Differences between UM and BP-I have been demonstrated in epidemiological, clinical, and genetic studies, therefore, including heterogeneous patients within the same category could hinder the interpretation of studies and limit advances in the knowledge of both disorders. Conclusion: Based on the literature review, it is suggested that UM should be recognized as an independent diagnosis. Despite its low prevalence, by validating it as such, in the future we could have more and better-quality data about this diagnosis. In this way, its distinctive characteristics can be defined more concretely, and therefore improve the clinical approach of these patients.
简介:单极躁狂(UM)是一种表现不同于双相i型障碍(BP-I)的障碍,然而,目前的诊断手册不认为它是一个独立的实体,而是包括在BP-I的诊断中。病例报告:一名21岁的男性出现了长达3个月的发作,其特征是情绪高涨和情绪一致的精神病症状。病人否认有过抑郁发作。采用锂离子联合阿立哌唑治疗,5年随访无复发,效果满意。文献回顾和讨论:诊断手册描述,要诊断BP-I,不需要出现重度抑郁发作,这意味着UM患者与BP-I患者属于相同的诊断类别。UM和BP-I之间的差异已在流行病学、临床和遗传学研究中得到证实,因此,将异质患者纳入同一类别可能会阻碍研究的解释,并限制对这两种疾病的认识的进展。结论:在文献回顾的基础上,建议将UM视为一种独立的诊断。尽管它的患病率很低,但通过验证它,在未来我们可以获得更多和更高质量的关于这种诊断的数据。这样可以更具体地定义其独特的特征,从而改善这些患者的临床治疗方法。
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引用次数: 0
El rol del placebo frente a los antidepresivos y aportes a la relación médico-paciente 安慰剂与抗抑郁药的作用及其对医患关系的贡献
Q4 Medicine Pub Date : 2021-12-01 DOI: 10.4067/s0717-92272021000400334
Felipe León C, Daniela Silva E, José Villagrán L
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引用次数: 0
Tratamiento quirúrgico de la epilepsia asociada a tumores neuroepiteliales de bajo grado. 低级别神经上皮肿瘤相关癫痫的外科治疗。
Q4 Medicine Pub Date : 2021-12-01 DOI: 10.4067/s0717-92272021000400321
Francisco Rojas Z, V. Venegas S., Cecilia Okuma P, O. Koller C., Sonia Ponce de Leon M, Carmen Olbrich G, Mauro Medeiros F
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引用次数: 0
Carcinomatosis meníngea secundaria a melanoma metastásico – reporte de un caso 继发性脑膜癌继发于转移性黑色素瘤-一例报告
Q4 Medicine Pub Date : 2021-12-01 DOI: 10.4067/s0717-92272021000400375
Francisca Iglesias C, J. Castellón V, Grecia Castro C, Catalina Silva H
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引用次数: 0
Estrategias no farmacológicas en personas con Demencia Avanzada: reporte de un caso. 晚期痴呆患者的非药物策略:病例报告。
Q4 Medicine Pub Date : 2021-12-01 DOI: 10.4067/s0717-92272021000400368
F. Acevedo P., Carolina Delgado Derio, G. Farías
In the course of dementia, the advanced stage is characterized by severe cognitive and physical impairment, defining it as a stage that includes deep memory deficits, minimal verbal skills, inability to walk independently, need of assistance to perform any basic daily life activity and urinary and fecal incontinence. The aim of this report is to describe a case of a 89-year-old woman with Advanced Dementia who goes to neurological control in the company of her family, who request information on how to improve the quality of life at this stage. We describe a proposal of palliative care approach, specifically the active therapeutic conception, as a guide that allows to observe the person not only from the good dying, but also from the incorporation of a proactive attitude in function of well-being. This approach allows to facilitate pleasurable experiences, defined within the framework of Nonpharmacological intervention, which have shown important benefits in people with advanced dementia in the last decade, allowing the identification of intervention strategies in this stage of the disease.
在痴呆过程中,晚期以严重的认知和身体损伤为特征,将其定义为包括深度记忆缺陷、最低限度的语言技能、无法独立行走、需要协助进行任何基本日常生活活动以及小便失禁的阶段。本报告的目的是描述一个89岁晚期痴呆症妇女的病例,她在家人的陪伴下进行神经控制,她的家人要求提供有关如何改善这一阶段生活质量的信息。我们描述了姑息治疗方法的建议,特别是积极的治疗概念,作为一种指导,不仅可以从好的死亡中观察到人,而且还可以从积极的态度融入到幸福的功能中。这种方法可以促进愉快的体验,在非药物干预的框架内定义,这在过去十年中对晚期痴呆症患者显示出重要的益处,允许在疾病的这一阶段确定干预策略。
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引用次数: 0
Habilidades de la Terapia Dialéctica Conductual en el contexto de la pandemia por COVID-19. COVID-19大流行背景下的行为辩证治疗技能。
Q4 Medicine Pub Date : 2021-12-01 DOI: 10.4067/s0717-92272021000400379
Joshep Revilla Z., Lesly Vargas B., Kalet Rojas M., Edson Quintana C., Franco Sotelo Q.
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引用次数: 0
期刊
Revista Chilena de Neuro-Psiquiatria
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