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Proceedings of the IEEE 23rd Northeast Bioengineering Conference最新文献

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Measurement of physiological stress 生理应激测量
Pub Date : 1997-05-21 DOI: 10.1109/NEBC.1997.594939
S. Reisman
In this tutorial paper, the methods presently used for measuring the degree of stress and relaxation in human physiology are discussed. Measurements include heart rate variability, respiration, blood levels of substance such as cortisol and catecholamine levels, EEG effects and the change in peripheral blood flow. Examples of methods presently used in the author's laboratory are described.
在这篇教程中,讨论了目前用于测量人体生理学中压力和放松程度的方法。测量包括心率变异性、呼吸、皮质醇和儿茶酚胺等血液物质水平、脑电图影响和外周血流量的变化。目前在作者的实验室中使用的方法的例子进行了描述。
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引用次数: 55
An analysis of race walking styles using a 2-dimensional mathematical knee model 用二维数学膝盖模型分析竞走方式
Pub Date : 1997-05-21 DOI: 10.1109/NEBC.1997.594963
B. Odegard, N. Bulat, B. Savilonis, Y. Mendelson
Describes a method developed to assess the contact forces in the knee due to different race walking techniques. Current rules require the walker's leg to be straightened upon impact with the ground, while previous rules allowed the leg to be bent until it passed beneath the walker's center of gravity. A system incorporating EMG, force plate readings, and kinematic video analysis was used in conjunction with a 2-D mathematical model of the lower leg. The model was developed to be applicable at initial impact. Significant differences were found between the two techniques in terms of the contact forces as well as accelerations of the tibia during impact.
描述了一种评估不同竞走技术对膝关节接触力影响的方法。目前的规则要求步行者的腿在撞击地面时要伸直,而以前的规则允许腿弯曲,直到它经过步行者的重心以下。结合肌电图、测力板读数和运动视频分析的系统与小腿的二维数学模型结合使用。该模型的开发是为了适用于初始冲击。在接触力以及胫骨在冲击过程中的加速度方面,发现了两种技术之间的显著差异。
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引用次数: 1
A simulation study of unwhitened versus whitened EMG amplitude estimation 非白化与白化肌电信号振幅估计的仿真研究
Pub Date : 1997-05-21 DOI: 10.1109/NEBC.1997.594954
E. Clancy, N. Hogan
Amplitude estimates of simulated surface electromyograms (EMGs) were studied using both unwhitened and whitened EMG amplitude estimators. Constant-effort non-fatiguing EMGs were simulated as the superposition of simple synthetic motor unit action potential trains (MUAPTs). Each MUAPT was formed from random firings of randomly shaped motor unit action potentials. Two aspects of unwhitened vs. whitened amplitude estimators were studied: (1) the relationship between the mean value of the EMG amplitude estimate vs. the level of contraction and (2) the signal-to-noise-ratio (SNR) performance of the EMG amplitude estimate. It was found that the relationships between estimated EMG amplitude vs. MUAPT firing rate and the number of MUAPTs were not altered by whitening. However, the performance of whitened amplitude estimators was markedly better. These results suggest that whitening can provide a higher fidelity EMG amplitude estimate without distorting the relationship between EMG and the mechanical output of the muscle.
利用未白化和白化的肌电信号振幅估计器对模拟表面肌电信号的振幅估计进行了研究。恒用力非疲劳肌电信号模拟为简单合成运动单元动作电位序列(MUAPTs)的叠加。每个MUAPT是由随机形状的运动单元动作电位随机放电形成的。研究了未漂白和漂白幅度估计器的两个方面:(1)肌电信号幅度估计的平均值与收缩水平之间的关系;(2)肌电信号幅度估计的信噪比(SNR)性能。结果发现,肌电估计振幅与MUAPT放电速率和MUAPT数量之间的关系未因白化而改变。然而,白化幅度估计器的性能明显更好。这些结果表明,美白可以提供更高保真度的肌电信号振幅估计,而不会扭曲肌电信号和肌肉机械输出之间的关系。
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引用次数: 0
Signal processing of systolic arterial blood pressure and heart rate variability in conscious rats 有意识大鼠收缩压和心率变异性的信号处理
Pub Date : 1997-05-21 DOI: 10.1109/NEBC.1997.594943
X. Tang, S. Reisman, W. Guo, S.A. Soldan
A signal processing algorithm to derive spectra of systolic blood pressure (SBP) and heart rate variability (HRV) in conscious rats is reported. In this algorithm, the carotid arterial blood pressure is acquired and the rhythmic fluctuations in SBP and HRV are analyzed with a spectral technique based on the fast Fourier transform. Three major components were examined in the spectra of both SBP and HRV, a high frequency component (HF) synchronized by respiration, a low-frequency component (LF) at a frequency of /spl sim/0.5 Hz and a very low-frequency component (VLF) at frequencies below 0.5 Hz.
本文报道了一种提取有意识大鼠收缩压(SBP)和心率变异(HRV)频谱的信号处理算法。该算法采用基于快速傅里叶变换的频谱技术,采集颈动脉血压,分析收缩压和HRV的节律性波动。在SBP和HRV的频谱中检测了三个主要成分,即呼吸同步的高频成分(HF),频率为/spl sim/0.5 Hz的低频成分(LF)和频率低于0.5 Hz的极低频成分(VLF)。
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引用次数: 0
The relationships between heart rate variability and cardiovascular reactivity 心率变异性与心血管反应性之间的关系
Pub Date : 1997-05-21 DOI: 10.1109/NEBC.1997.594940
M. Deprince, S. Reisman
A key function of the autonomic nervous system is to alter physiological variables, such as heart rate and blood pressure, in order to accommodate changes in the body due to stressful or relaxing situations. Research in both the fields of heart rate variability and cardiovascular reactivity have studied the physiological effects of many different tasks, such as mental arithmetic. Very few studies, however, have investigated whether there is a correlation between heart rate variability and cardiovascular reactivity measurements. The main objective of the present study is to gain further insight about the relationships between noninvasive measures of parasympathetic activity and cardiovascular reactivity. In order to better fulfill this objective, aspects of data analysis techniques, experimental designs and protocols for the present study are changed from those used in previous research.
自主神经系统的一个关键功能是改变生理变量,如心率和血压,以适应身体因压力或放松情况而发生的变化。心率变异性和心血管反应性领域的研究已经研究了许多不同任务的生理效应,例如心算。然而,很少有研究调查心率变异性和心血管反应性测量之间是否存在相关性。本研究的主要目的是进一步了解副交感神经活动的非侵入性测量与心血管反应性之间的关系。为了更好地实现这一目标,本研究的数据分析技术、实验设计和方案方面都与以前的研究中使用的有所不同。
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引用次数: 1
Noninvasive real time observation of His bundle activity 无创实时观察他的束活动
Pub Date : 1997-05-21 DOI: 10.1109/NEBC.1997.594967
G. Benko
While seeking a particular lead combination that would demonstrate the His bundle impulse noninvasively, an esophageal lead system was found that shows a clear cut positive going ramp in the final 40 msec of the P-R segment. Using a dual beam oscilloscope in a totally shielded true hi-fi system, tracings showed this ramp occurs immediately before the QRS of chest leads. With its timing, polarity and electrode placement it appears that it can only arise from His bundle (nodobundle) activity. Tracings are presented which show how electromagnetic interference obscures this and other P-R interval signals illustrating the need for true hi-fi conditions in ECG research.
在寻找一种特殊的导联组合以无创性地显示His束脉冲时,我们发现了一种食管导联系统,在P-R段的最后40毫秒显示出明显的正向斜坡。在完全屏蔽的真高保真系统中使用双波束示波器,跟踪显示这种斜坡发生在胸部引线QRS之前。从它的时间、极性和电极位置来看,它似乎只能由他的束(结节束)活动引起。示踪显示了电磁干扰是如何模糊这个和其他P-R间隔信号的,说明了在ECG研究中需要真正的高保真条件。
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引用次数: 0
An artificial neural network for neural spike classification 神经脉冲分类的人工神经网络
Pub Date : 1997-05-21 DOI: 10.1109/NEBC.1997.594936
J. Stitt, R. Gaumond, J. L. Frazier, F. Hanson
In insects, the summed responses of neural activity can be obtained by recording from the exterior of a taste organ (sensillum) of an intact animal. These multiunit recordings are commonly used to understand sensory and behavioral physiology. It is possible to distinguish between the neural spikes produced by these chemosensory neurons using such features as amplitude and shape. We have developed an artificial neural network (ANN) spike classifier which is capable of distinguishing among neural responses of each insect taste organ. The ANN is "trained" on prototypical spikes produced by each of the constituent neurons. It performs very well when compared with conventional optimal methods of template matching and principal components.
在昆虫中,神经活动的总反应可以通过记录完整动物的味觉器官(感受器)的外部来获得。这些多单元记录通常用于理解感觉和行为生理学。利用振幅和形状等特征来区分这些化学感觉神经元产生的神经尖峰是可能的。我们开发了一种能够区分昆虫各味觉器官神经反应的人工神经网络(ANN)脉冲分类器。人工神经网络是根据每个组成神经元产生的典型尖峰进行“训练”的。与传统的模板匹配和主成分优化方法相比,该方法具有较好的效果。
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引用次数: 3
CdZnTe strip detectors as sub-millimeter resolution imaging gamma radiation spectrometers 作为亚毫米分辨率成像伽玛辐射光谱仪的CdZnTe条带探测器
Pub Date : 1997-05-21 DOI: 10.1109/NEBC.1997.594956
K. Larson, D. V. Boykin, M. Cherry, J. Courville, F. Doty, A. Drake, T. G. Guzik, L. Hamel, J. Macri, M. Mayer, M. McConnell, J. Ryan, O. Tousignant
We report /spl gamma/-ray detection performance measurements and computer simulations of a sub-millimeter pitch CdZnTe strip detector. The detector is a prototype for /spl gamma/-ray measurements in the range of 20-600 keV. The prototype is a 1.5 mm thick, 64/spl times/64 orthogonal stripe CdZnTe detector of 0.375 mm pitch in both dimensions, with approximately one square inch of sensitive area. Using discrete laboratory electronics to process signals from an 8/spl times/8 stripe region of the prototype we measured good spectroscopic uniformity and sub-pitch (/spl sim/0.2 mm) spatial resolution in both x and y dimensions. We present below measurements of the spatial uniformity, relative timing and pulse height of the anode and cathode signals. We simulated the photon interactions and signal generation in the strip detector and the test electronics and we compare these results with the data. The data indicate that cathode signal-as well as the anode signal-arises more strongly from the conduction electrons rather than the holes.
我们报道了一种亚毫米间距CdZnTe条带探测器的/spl伽马/射线探测性能测量和计算机模拟。该探测器是在20-600 keV范围内/spl伽马/射线测量的原型。该原型是一个1.5 mm厚,64/spl倍/64正交条纹CdZnTe探测器,两个维度的间距为0.375 mm,敏感区域约为1平方英寸。使用离散实验室电子技术处理来自原型的8/spl次/8条纹区域的信号,我们在x和y维度上测量了良好的光谱均匀性和亚间距(/spl sim/0.2 mm)空间分辨率。下面我们给出了空间均匀性、相对定时和阳极和阴极信号脉冲高度的测量结果。我们模拟了光子在条带探测器和测试电子学中的相互作用和信号的产生,并将这些结果与数据进行了比较。数据表明,阴极信号——以及阳极信号——更强烈地来自传导电子而不是空穴。
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引用次数: 0
Optical glucose sensor using a single Faraday rotator 使用单个法拉第旋转器的光学葡萄糖传感器
Pub Date : 1997-05-21 DOI: 10.1109/NEBC.1997.594934
Sunghoon Jang, M. D. Fox
A new approach to non-invasive closed loop optical glucose sensing has been proposed. Incident light on the cornea travels into the eye and reflects from the retina. The reflected light contains information about glucose concentration in the aqueous humor which can potentially be used to measure long term and instantaneous blood glucose concentration. Previous designs have utilized two Faraday rotators to create a closed loop system. The data reported here indicates that only one Faraday rotator is actually needed for this system. The modifications not only cut the system cost substantially, but also improve sensitivity by 143%, over a two Faraday rotator implementation.
提出了一种无创闭环光学葡萄糖传感的新方法。入射到角膜上的光进入眼睛并从视网膜反射出来。反射光包含房水中葡萄糖浓度的信息,可以潜在地用于测量长期和瞬时血糖浓度。以前的设计利用两个法拉第旋转器来创建一个闭环系统。这里报告的数据表明,该系统实际上只需要一个法拉第旋转器。这些改进不仅大大降低了系统成本,而且与两个法拉第旋转器相比,灵敏度提高了143%。
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引用次数: 10
Doppler ultrasound determination of capillary blood flow 多普勒超声测定毛细血管血流
Pub Date : 1997-05-21 DOI: 10.1109/NEBC.1997.594927
D. Raunig, M. Fox
The authors describe preliminary efforts to measure the human microcirculation with conventional CW Doppler ultrasound equipment. The results suggest that it may be possible to detect and measure capillary flow in this way. The broad spectrum expected from capillary returns, rather than a single-point capillary velocity, could potentially provide information of the statistics of the flow. Overall, the preliminary results obtained thus far are encouraging in terms of the potential for developing methodologies for utilizing Doppler ultrasound to assess general end organ tissue perfusion.
作者描述了用常规连续波多普勒超声设备测量人体微循环的初步努力。结果表明,用这种方法检测和测量毛细管流量是可行的。毛细管回流的广谱预期,而不是单点毛细管速度,可以潜在地提供流量统计信息。总的来说,就开发利用多普勒超声评估一般终末器官组织灌注的方法的潜力而言,迄今为止获得的初步结果令人鼓舞。
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引用次数: 2
期刊
Proceedings of the IEEE 23rd Northeast Bioengineering Conference
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