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Proceedings of the IEEE 23rd Northeast Bioengineering Conference最新文献

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A data logging system using optical sensing techniques to determine foraging strategies of cottontail rabbits 利用光学传感技术确定棉尾兔觅食策略的数据记录系统
Pub Date : 1997-05-21 DOI: 10.1109/NEBC.1997.594947
D. F. Smith, W. Smith, J. Lacourse, J. A. Litvaitis
Adaptive foraging decisions yield information on how animals view their environment. These decisions allow researchers to know how foragers rank habitats. We used a data logging system using infrared break-beam circuitry to evaluate these decisions. The data from this system revealed differences in behaviors between two species of cottontail rabbits in outdoor enclosures where obtaining food incurs predation costs (probability of mortality).
适应性觅食决策提供了动物如何看待环境的信息。这些决定让研究人员知道觅食者如何对栖息地进行排序。我们使用了一个使用红外断束电路的数据记录系统来评估这些决策。来自该系统的数据揭示了在室外围场中获取食物会产生捕食成本(死亡概率)的两种棉尾兔之间的行为差异。
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引用次数: 3
Measurement of upper airway dimensions during inspiratory flow 吸气流动时上呼吸道尺寸的测量
Pub Date : 1997-05-21 DOI: 10.1109/NEBC.1997.594944
S. Jo, R. Gaumond
We examined the effectiveness of two-microphone acoustic reflection pharyngometry in determining the changes in the human upper airway collapsible segment during steady inspiratory flow conditions. Differences in oral airway dimensions of a male subject, at 3 flow levels, were analyzed. The physiological data, then, was applied to a mathematical model of airway collapse, and the coefficient of collapse (C/sub c/) was calculated. The collapsible segment was approximately 10 cm in length, and was located between the oro-pharyngeal junction (OPJ), and the glottis; the entire segment was susceptible to area decrease at a flow rate of 500 ml/s. C/sub c/ calculation indicated that full collapse would not occur during our experimental conditions, which was validated by pharyngometry.
我们研究了双麦克风声反射咽测法在确定稳定吸气流条件下人类上呼吸道可折叠段变化的有效性。分析了一名男性受试者在3个流量水平下口腔气道尺寸的差异。将生理数据应用于气道塌陷数学模型,计算气道塌陷系数(C/sub C/)。可折叠节段长约10 cm,位于口咽交界处(OPJ)和声门之间;在500ml /s的流速下,整个片段的面积都容易减小。C/sub C/计算表明,在我们的实验条件下,不会发生完全坍缩,这一点得到了咽检的验证。
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引用次数: 0
Pulse wave velocity for cardiovascular characterization 用于心血管表征的脉搏波速度
Pub Date : 1997-05-21 DOI: 10.1109/NEBC.1997.594965
D. Charles, M. Fox
Pulse wave velocity (PWV) provides a robust metric for cardiovascular health that can readily be measured non-intrusively. This paper describes efforts to develop a methodology for rapid, portable, cost effective measurement of pulse wave velocity utilizing only an electrocardiogram (EGG), continuous wave (CW) Doppler, and a computer based data acquisition board. Preliminary results showed that the pulse wave velocity from the aortic root to the radial artery could be deduced with access only to distal portions of the upper extremities, thus minimizing the subject's inconvenience, and making the measurement very suitable for screening applications. In the pilot study reported here, aortic-radial pulse wave transit time was found to be 294.2 ms averaged over 9 pulses with the standard error of the sample mean=9.22 ms. The pulse wave velocity was 217.5 cm/s with standard error of the sample mean=7.07 cm/s.
脉搏波速度(PWV)为心血管健康提供了一个可靠的指标,可以很容易地进行非侵入性测量。本文描述了开发一种快速、便携、经济有效的脉搏波速度测量方法的努力,该方法仅利用心电图(EGG)、连续波(CW)多普勒和基于计算机的数据采集板。初步结果表明,仅通过上肢远端部分即可推断出从主动脉根部到桡动脉的脉搏波速度,从而最大限度地减少了受试者的不便,并且使测量非常适合筛选应用。在本文报道的先导研究中,发现主动脉-桡动脉脉冲波传递时间为294.2 ms,平均9次脉冲,样本平均值的标准误差为9.22 ms。脉冲波速为217.5 cm/s,样品平均标准误差为7.07 cm/s。
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引用次数: 1
Muscle tissue ischemia monitoring using impedance spectroscopy: analysis of R/sub 0/ and /spl tau/ variations with ischemia 用阻抗谱监测肌肉组织缺血:分析R/sub 0/和/spl tau/随缺血的变化
Pub Date : 1997-05-21 DOI: 10.1109/NEBC.1997.594932
B. Ristic, S. Kun, R. Peura
Impedance spectroscopy is a promising method for tissue ischemia monitoring. Ischemia causes changes in tissue impedance that can be detected by impedance spectroscopic measurements. This technique has numerous advantages over existing ischemia monitoring methods: it is non-invasive and suitable for long term and continuous use. To fully develop this method, we experimentally investigated the relationships between ischemia and tissue impedance. For this purpose, in-vivo animal experiments were conducted, Results show complex, nonlinear relationships between tissue impedance and ischemia. Previous studies identified R/sub 0/ (DC impedance) as the parameter most sensitive to ischemia. However, R/sub 0/ variations are quite non-specific, therefore R/sub 0/ cannot be quantitatively correlated to ischemia. In this paper, we present an analysis which indicates that ischemia induced variations of the tissue time constant /spl tau/ are well correlated to R/sub 0/ and pH variations. /spl tau/ has a better sensitivity and a higher level of specificity to ischemia variations, compared to R/sub 0/. This is evidence that /spl tau/ is a powerful indicator of tissue ischemia.
阻抗谱是一种很有前途的组织缺血监测方法。缺血引起组织阻抗的变化,这可以通过阻抗光谱测量来检测。与现有的缺血监测方法相比,该技术具有许多优点:它是非侵入性的,适合长期和连续使用。为了充分发展这一方法,我们实验研究了缺血与组织阻抗之间的关系。为此,进行了活体动物实验,结果显示组织阻抗与缺血之间存在复杂的非线性关系。已有研究认为直流阻抗(R/sub 0/)是对缺血最敏感的参数。然而,R/sub 0/的变化是非特异性的,因此R/sub 0/不能定量地与缺血相关。在本文中,我们提出了一项分析,表明缺血引起的组织时间常数/spl tau/的变化与R/sub /和pH变化有很好的相关性。与R/sub 0/相比,/spl tau/对缺血变化具有更好的敏感性和更高的特异性。这证明/spl tau/是组织缺血的一个强有力的指标。
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引用次数: 1
Effects of neural entrainment within a biologically realistic network 神经夹带在生物现实网络中的作用
Pub Date : 1997-05-21 DOI: 10.1109/NEBC.1997.594937
J. Canfield, M. Carter
A network of realistic neuron models interconnected by Hebbian synapses is shown to be capable of autoassociative recall. However, a collective network property, the robust entrainment of activity between neurons, leads to several interesting network level phenomena not seen in attractor networks with conventional neuron models. These include phase-locked bursting patterns of neural activity, the temporal segmentation of mixed pattern input cues, and the functionality to serve as a subunit for the storage of temporal sequences. Given the previously established accuracy of the utilized single neuron model as a reduced order approximation of the Hodgkin-Huxley equations, these findings are well suited for comparison with their biological correlates.
一个由Hebbian突触相互连接的现实神经元模型网络被证明能够进行自联想回忆。然而,一个集体网络特性,即神经元之间的活动的鲁棒性,导致了一些有趣的网络水平现象,这些现象在传统的神经元模型的吸引子网络中是看不到的。其中包括神经活动的锁相爆发模式,混合模式输入线索的时间分割,以及作为存储时间序列的亚单元的功能。考虑到先前建立的单神经元模型作为霍奇金-赫胥黎方程的降阶近似的准确性,这些发现非常适合与它们的生物学相关性进行比较。
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引用次数: 0
Continuous monitoring of patients being weaned from mechanical ventilation 持续监测脱离机械通气的患者
Pub Date : 1997-05-21 DOI: 10.1109/NEBC.1997.594969
G.D. Gaebe, R. Peura
Mechanical ventilation is an important lifesaving tool in the modern ICU, but just as critical as its use is knowing when to wean a patient from it. This study used the new technology of the continuous metabolic monitor coupled with auto and cross correlation analyses to discern differences between pass and fail patient groups during weaning trials. These dynamic analyses were compared to the mean values of respiratory parameters commonly used by clinicians. It was found that the cross correlation function differences were more significant than differences in all parameters examined, except ventilatory equivalent.
在现代ICU中,机械通气是一种重要的救生工具,但与它的使用同样重要的是,知道何时让病人脱离它。本研究采用连续代谢监测的新技术,结合自动和交叉相关分析来辨别在断奶试验中通过和失败患者组之间的差异。将这些动态分析结果与临床医生常用的呼吸参数平均值进行比较。结果发现,除通风量外,相关函数的差异比其他参数的差异更显著。
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引用次数: 0
Performance monitoring from the EEG power spectrum with a radial basis function neural network 基于径向基函数神经网络的脑电功率谱性能监测
Pub Date : 1997-05-21 DOI: 10.1109/NEBC.1997.594938
B.P. Kirk, J. LaCourse
Length of vigilance is a major obstacle in jobs associated with low levels of arousal. To provide the highest levels of safety, the level of attention, particularly visual awareness, has to be monitored. A system has been designed, offline, as a precedent to a real-time awareness predictor. The electroencephalograph (EEG) is used as the major predictive data with a radial basis function network classifying the attention level.
警觉性持续时间长是与低唤醒水平相关的工作的主要障碍。为了提供最高水平的安全,必须监测注意力水平,特别是视觉意识。已经设计了一个离线系统,作为实时感知预测器的先例。以脑电图(EEG)作为主要预测数据,采用径向基函数网络对注意力水平进行分类。
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引用次数: 1
Low cost rodent activity monitoring instrumentation 低成本啮齿动物活动监测仪器
Pub Date : 1997-05-21 DOI: 10.1109/NEBC.1997.594946
M. Bergen, S.A. Soldan, S. Reisman, J. Ottenweller
Chronic fatigue syndrome (CFS) is a condition that results in moderate to severe disability. A leading symptom of CFS is that patients report critical reductions in their levels of physical activity due to fatigue related symptoms. We have developed a rodent model, using rats, hamsters, and mice, that enables us to investigate fatigue and physiological rhythms in an integrated framework. The animal's activity is one measure of great importance in the study of these rhythms and chronic fatigue. To monitor a free-ranging rodent's activity we utilize two complementing methods: first, is an infra-red photo beam to detect and count turns of a running wheel, and second, is a force sensor located under the housing tub to detect general motion. Both methods are used in the animal's home cage and are made to be low cost, compared to commercial units, for implementation on many animals.
慢性疲劳综合症(CFS)是一种导致中度至重度残疾的疾病。慢性疲劳综合症的一个主要症状是,患者报告说,由于疲劳相关症状,他们的体力活动水平急剧下降。我们开发了一种啮齿类动物模型,使用大鼠、仓鼠和小鼠,使我们能够在一个综合框架中研究疲劳和生理节律。动物的活动是研究这些节律和慢性疲劳的一个非常重要的指标。为了监测自由放养的啮齿动物的活动,我们使用了两种互补的方法:第一种是红外光束,用于检测和计数运行轮的转动,第二种是位于房屋桶下的力传感器,用于检测一般运动。这两种方法都是在动物的家庭笼子中使用的,与商业单位相比,成本较低,适用于许多动物。
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引用次数: 0
Paced breathing controller using LabView 使用LabView的节奏呼吸控制器
Pub Date : 1997-05-21 DOI: 10.1109/NEBC.1997.594945
L. Hendrickson, P. Engler
Paced breathing devices are designed and used for exactly that - paced breathing. Often when a researcher is conducting an experiment that requires biological signals to be analyzed, the number of variables are reduced by keeping all of the subject's rate of breaths per minute (BPM) the same. Presently there exists both software and hardware that serves the purpose for this task. This project has combined both of these to build a new apparatus using the latest technology. Instead of a hardware device which is difficult to manipulate once constructed, the software package LabVIEW (Laboratory Virtual Instrument Engineering Workbench) Is used to construct this device. LabVIEW is a icon driven package which parallels actual electrical components. If the situation arises in which changes need to be made, they can be performed relatively easily assuming there is some knowledge of the software at hand. The convenience of this arises because manipulations can be made without the use of a soldering iron or any other tool with the exception of a mouse.
节奏呼吸装置被精确地为那节奏呼吸设计和使用。通常,当研究人员进行一项需要分析生物信号的实验时,通过保持所有受试者的每分钟呼吸率(BPM)相同,可以减少变量的数量。目前有软件和硬件服务于这个任务的目的。这个项目将这两者结合起来,用最新的技术建造了一个新的设备。采用LabVIEW(实验室虚拟仪器工程工作台)软件来代替硬件设备的构造,避免了硬件设备的构造难以操作。LabVIEW是一个图标驱动的包,它与实际的电子元件并行。如果出现需要进行更改的情况,那么假设手头有一些软件知识,可以相对容易地执行这些更改。这样做的便利性是因为操作可以在不使用烙铁或任何其他工具的情况下进行,除了鼠标。
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引用次数: 0
High frequency ultrasound tissue characterization 高频超声组织表征
Pub Date : 1997-05-21 DOI: 10.1109/NEBC.1997.594949
Martin D. Fox, W. Pruehsner
Ultrasound tissue characterization has generally been carried out in the 1-5 MHz frequency range. In the present research, we looked into methodologies to extend tissue characterization to the 10-50 MHz domain. Preliminary experiments were carried out using transducers constructed from PVDF. Initial results suggested that frequencies from 8-20 MHz could readily be detected through tissue samples in a 3.5 cm test cell. Spectrum analysis of averaged and digitized transmitted bursts revealed differences in the transmission spectra for different tissue samples placed in the test cell.
超声组织表征一般在1-5 MHz频率范围内进行。在目前的研究中,我们研究了将组织表征扩展到10-50 MHz域的方法。用PVDF制成的换能器进行了初步实验。初步结果表明,在3.5厘米的测试细胞中,可以很容易地通过组织样品检测到8-20 MHz的频率。平均和数字化发射脉冲的频谱分析揭示了放置在测试细胞中的不同组织样品的透射光谱的差异。
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引用次数: 4
期刊
Proceedings of the IEEE 23rd Northeast Bioengineering Conference
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