{"title":"One medicine: The need for a common conceptual framework","authors":"A. Morandi","doi":"10.4103/jras.jras_82_23","DOIUrl":"https://doi.org/10.4103/jras.jras_82_23","url":null,"abstract":"","PeriodicalId":394246,"journal":{"name":"Journal of Research in Ayurvedic Sciences","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128246953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BACKGROUND: Iron deficiency anemia (IDA) is a major health problem among children in India. Due to the adverse effects of oral iron supplementation, there is a need to find an alternative therapeutic option for IDA, which is safe, tolerable, with comparable efficacy. OBJECTIVE: This clinical study is designed to determine the efficacy and safety of Darvyadi Leha in IDA of children compared with ferrous ascorbate. MATERIALS AND METHODS: This prospective, open-label, randomized, active control, parallel-group trial will be conducted at Uttarakhand Ayurved University, Gurukul Campus, Haridwar. A total of 76 participants will be enrolled in the study. Patients of any gender aged 3–12 years with IDA, having hemoglobin 7.5–11 g/dL and serum ferritin less than 15 mcg/dL will be considered for enrollment in the study. The enrolled participants will be given a tablet of Albendazole 400-mg single dose for deworming. Thereafter, they will be randomly divided into two groups. Patients of Group A will be administered Darvyadi Leha 4, 7, 9, and 12 g/day in two equally divided doses for age groups 3–5, 5–8, 8–10, and 10–12 years, respectively, for 90 days. Patients of group B will be administered ferrous ascorbate 4 mg/kg/day twice daily for 90 days. The outcome measures are changes in hemoglobin level, ferritin level, red blood cell count, mean corpuscular volume, mean corpuscular hemoglobin, and reticulocyte count. Patients will also be assessed for graded subjective parameters on each visit. Safety will be assessed based on the incidence of adverse events, and changes in liver and kidney function tests. DISCUSSION: Ayurveda formulations have been used for the management of anemia in routine clinical practice for adults. Further, several research studies have also been conducted regarding the same. However, the use of Ayurveda interventions in anemia of children is less common, and a few randomized controlled studies on anemia of children have been conducted. So, it is expected that the outcomes of this trial will suggest probable therapeutic options for the effective management of IDA of children. TRIAL REGISTRATION: CTRI/2022/07/044074
{"title":"A prospective, open-label, randomized, active control, parallel-group trial on the efficacy of Darvyadi Leha in iron deficiency anemia of children: Study protocol of a randomized controlled trial","authors":"Deepshikha Rai, Girraj Garg","doi":"10.4103/jras.jras_71_23","DOIUrl":"https://doi.org/10.4103/jras.jras_71_23","url":null,"abstract":"BACKGROUND: Iron deficiency anemia (IDA) is a major health problem among children in India. Due to the adverse effects of oral iron supplementation, there is a need to find an alternative therapeutic option for IDA, which is safe, tolerable, with comparable efficacy. OBJECTIVE: This clinical study is designed to determine the efficacy and safety of Darvyadi Leha in IDA of children compared with ferrous ascorbate. MATERIALS AND METHODS: This prospective, open-label, randomized, active control, parallel-group trial will be conducted at Uttarakhand Ayurved University, Gurukul Campus, Haridwar. A total of 76 participants will be enrolled in the study. Patients of any gender aged 3–12 years with IDA, having hemoglobin 7.5–11 g/dL and serum ferritin less than 15 mcg/dL will be considered for enrollment in the study. The enrolled participants will be given a tablet of Albendazole 400-mg single dose for deworming. Thereafter, they will be randomly divided into two groups. Patients of Group A will be administered Darvyadi Leha 4, 7, 9, and 12 g/day in two equally divided doses for age groups 3–5, 5–8, 8–10, and 10–12 years, respectively, for 90 days. Patients of group B will be administered ferrous ascorbate 4 mg/kg/day twice daily for 90 days. The outcome measures are changes in hemoglobin level, ferritin level, red blood cell count, mean corpuscular volume, mean corpuscular hemoglobin, and reticulocyte count. Patients will also be assessed for graded subjective parameters on each visit. Safety will be assessed based on the incidence of adverse events, and changes in liver and kidney function tests. DISCUSSION: Ayurveda formulations have been used for the management of anemia in routine clinical practice for adults. Further, several research studies have also been conducted regarding the same. However, the use of Ayurveda interventions in anemia of children is less common, and a few randomized controlled studies on anemia of children have been conducted. So, it is expected that the outcomes of this trial will suggest probable therapeutic options for the effective management of IDA of children. TRIAL REGISTRATION: CTRI/2022/07/044074","PeriodicalId":394246,"journal":{"name":"Journal of Research in Ayurvedic Sciences","volume":"72 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126435692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mann Ki Baat and the Ayush Sector: A Transformative Impact","authors":"V. Kotecha","doi":"10.4103/jras.jras_94_23","DOIUrl":"https://doi.org/10.4103/jras.jras_94_23","url":null,"abstract":"","PeriodicalId":394246,"journal":{"name":"Journal of Research in Ayurvedic Sciences","volume":"283 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115635570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of International Day of Yoga and thrust from the Government in bringing Yoga to daily lives of people","authors":"RaoM Raghavendra, HS Vadiraja, Ghanapriyari Moirangthem, Shalini Awasthi","doi":"10.4103/jras.jras_100_23","DOIUrl":"https://doi.org/10.4103/jras.jras_100_23","url":null,"abstract":"","PeriodicalId":394246,"journal":{"name":"Journal of Research in Ayurvedic Sciences","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124997522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-01DOI: 10.4103/jras.jras_106_23
T. Nesari, M. Kulkarni, Shivakumar Harti
{"title":"Ayurveda Aahara (Traditional Dietetics) - Untapped Potential","authors":"T. Nesari, M. Kulkarni, Shivakumar Harti","doi":"10.4103/jras.jras_106_23","DOIUrl":"https://doi.org/10.4103/jras.jras_106_23","url":null,"abstract":"","PeriodicalId":394246,"journal":{"name":"Journal of Research in Ayurvedic Sciences","volume":"86 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122415940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-01DOI: 10.4103/jras.jras_101_23
R. Naik, Rabina Acharya, A. Tripathi, D. Rajput
{"title":"Impact of Mann Ki Baat on Ayush Start-Ups","authors":"R. Naik, Rabina Acharya, A. Tripathi, D. Rajput","doi":"10.4103/jras.jras_101_23","DOIUrl":"https://doi.org/10.4103/jras.jras_101_23","url":null,"abstract":"","PeriodicalId":394246,"journal":{"name":"Journal of Research in Ayurvedic Sciences","volume":"50 12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126347731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Albuminuria is one of the most typical symptoms when there are derangements in the kidney functions, which may damage the kidney’s functional units, that is, nephrons. This study presents a case of a patient suffering from albuminuria who was diagnosed with crossed renal ectopia, that is, fused right kidney to the left side. A 61-year-old male patients suffered from generalized body weakness, proteinuria, disturbed sleep, and dysuria. Because of dysuria, the patient needed catheterization every fortnight. The patient had no history of addiction to smoking and alcohol. The patient had no history of diabetes mellitus, hypertension, or systemic disease except pulmonary tuberculosis 30 years back. The kidney function test, urine routine, and microscopy examination revealed albuminuria, the presence of bacteria, and elevated serum uric acid level. Crossed renal ectopia was diagnosed through a computed tomography examination. From an Ayurveda perspective, the diagnosis of Kaphaja Meha was based on the patient’s complaints, such as increased frequency of micturition and hazy/turbid urine. The treatment plan was made according to the management of Kaphaja Meha. Chandraprabha Vati, Punarnava Asava, Punarnava capsule, and SG syrup—an Ayurvedic formulation, were prescribed along with the dietary regimen. Follow-up was done seven times within 9 months. The medications and dose were altered according to the patient’s condition. The patient’s condition improved symptomatically. After the Ayurvedic intervention for 9 months and 23 days, albumin was absent in urine; serum uric acid became 4.90 mg/dL, and the glomerular filtration rate increased to 88/mL/min/1.73 m2. The patient had normal urination without needing catheterization. The case study results indicate that Ayurveda interventions can manage albuminuria and dysuria in patients with crossed renal ectopia.
{"title":"Management of albuminuria and dysuria through Ayurveda interventions in a patient with crossed renal ectopia: A case report","authors":"M. Suhail, Pramod Yadav, Pradeep Prajapati","doi":"10.4103/jras.jras_86_22","DOIUrl":"https://doi.org/10.4103/jras.jras_86_22","url":null,"abstract":"Albuminuria is one of the most typical symptoms when there are derangements in the kidney functions, which may damage the kidney’s functional units, that is, nephrons. This study presents a case of a patient suffering from albuminuria who was diagnosed with crossed renal ectopia, that is, fused right kidney to the left side. A 61-year-old male patients suffered from generalized body weakness, proteinuria, disturbed sleep, and dysuria. Because of dysuria, the patient needed catheterization every fortnight. The patient had no history of addiction to smoking and alcohol. The patient had no history of diabetes mellitus, hypertension, or systemic disease except pulmonary tuberculosis 30 years back. The kidney function test, urine routine, and microscopy examination revealed albuminuria, the presence of bacteria, and elevated serum uric acid level. Crossed renal ectopia was diagnosed through a computed tomography examination. From an Ayurveda perspective, the diagnosis of Kaphaja Meha was based on the patient’s complaints, such as increased frequency of micturition and hazy/turbid urine. The treatment plan was made according to the management of Kaphaja Meha. Chandraprabha Vati, Punarnava Asava, Punarnava capsule, and SG syrup—an Ayurvedic formulation, were prescribed along with the dietary regimen. Follow-up was done seven times within 9 months. The medications and dose were altered according to the patient’s condition. The patient’s condition improved symptomatically. After the Ayurvedic intervention for 9 months and 23 days, albumin was absent in urine; serum uric acid became 4.90 mg/dL, and the glomerular filtration rate increased to 88/mL/min/1.73 m2. The patient had normal urination without needing catheterization. The case study results indicate that Ayurveda interventions can manage albuminuria and dysuria in patients with crossed renal ectopia.","PeriodicalId":394246,"journal":{"name":"Journal of Research in Ayurvedic Sciences","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114306378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-01DOI: 10.4103/jras.jras_153_22
Kavita Vyas, Anubha Chandla, Vikas Nariyal, B. Yadav, Hetalben Amin, S. Khanduri, B. Sharma, Rakesh Rana, R. Singhal, Arunabh Tripathi, B. Chandrasekhararao, Narayanam Srikanth, K. Dhiman
BACKGROUND: Several studies have proven the immunomodulatory action of Guduchi (Tinospora cordifolia). Immunomodulation strategy is a crucial requirement to control coronavirus disease 2019 (COVID-19), the disease caused by severe acute respiratory syndrome coronavirus 2. Therefore, Guduchi Ghan Vati (GGV), tablets prepared from water extract of T. cordifolia, is selected to prevent COVID-19. OBJECTIVE: This study aimed to know the prophylactic effect of Ayurvedic intervention, that is GGV, in preventing COVID-19 infection among the community of containment areas. MATERIALS AND METHODS: It was an open-label, prospective, nonrandomized, community-based interventional study carried out from May 6 to June 23, 2020, in a containment zone (Bijhari) of District Hamirpur, Himachal Pradesh, India. GGV was given to the community in the dose of 500 mg twice a day with lukewarm water on an empty stomach for 30 days. The demographic and health-related data of the participants were collected using Google forms, and follow-up was done on the 30th day through telephonic interviews. RESULTS: A total of 1165 participants’ data were analyzed to assess the prophylactic effect of GGV. In the sample, 85.2% of participants had no systemic disorders, whereas 13.8% took concomitant medicines for other morbidities. The incidence of COVID-19-positive cases was only 0.1% (n = 01). CONCLUSION: Ayurvedic intervention GGV was found to have prophylactic potential against COVID-19 infection.
{"title":"An open-label prospective interventional study to assess the prophylactic effect of Guduchi Ghan Vati in COVID-19: A community-based study in containment zone of Himachal Pradesh, India","authors":"Kavita Vyas, Anubha Chandla, Vikas Nariyal, B. Yadav, Hetalben Amin, S. Khanduri, B. Sharma, Rakesh Rana, R. Singhal, Arunabh Tripathi, B. Chandrasekhararao, Narayanam Srikanth, K. Dhiman","doi":"10.4103/jras.jras_153_22","DOIUrl":"https://doi.org/10.4103/jras.jras_153_22","url":null,"abstract":"BACKGROUND: Several studies have proven the immunomodulatory action of Guduchi (Tinospora cordifolia). Immunomodulation strategy is a crucial requirement to control coronavirus disease 2019 (COVID-19), the disease caused by severe acute respiratory syndrome coronavirus 2. Therefore, Guduchi Ghan Vati (GGV), tablets prepared from water extract of T. cordifolia, is selected to prevent COVID-19. OBJECTIVE: This study aimed to know the prophylactic effect of Ayurvedic intervention, that is GGV, in preventing COVID-19 infection among the community of containment areas. MATERIALS AND METHODS: It was an open-label, prospective, nonrandomized, community-based interventional study carried out from May 6 to June 23, 2020, in a containment zone (Bijhari) of District Hamirpur, Himachal Pradesh, India. GGV was given to the community in the dose of 500 mg twice a day with lukewarm water on an empty stomach for 30 days. The demographic and health-related data of the participants were collected using Google forms, and follow-up was done on the 30th day through telephonic interviews. RESULTS: A total of 1165 participants’ data were analyzed to assess the prophylactic effect of GGV. In the sample, 85.2% of participants had no systemic disorders, whereas 13.8% took concomitant medicines for other morbidities. The incidence of COVID-19-positive cases was only 0.1% (n = 01). CONCLUSION: Ayurvedic intervention GGV was found to have prophylactic potential against COVID-19 infection.","PeriodicalId":394246,"journal":{"name":"Journal of Research in Ayurvedic Sciences","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127061221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Katiyar, Anirban Chakrabarty, S. Dubey, P. Pandey, Manash Tumulu, A. Narwaria
{"title":"Enhancing Quality of Ayush Products – Strategies and Efforts of the Ministry of Ayush and Ayush Industry","authors":"C. Katiyar, Anirban Chakrabarty, S. Dubey, P. Pandey, Manash Tumulu, A. Narwaria","doi":"10.4103/jras.jras_92_23","DOIUrl":"https://doi.org/10.4103/jras.jras_92_23","url":null,"abstract":"","PeriodicalId":394246,"journal":{"name":"Journal of Research in Ayurvedic Sciences","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126967389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Globalization of Ayurveda and Yoga: Status, Scope, Challenges, and Ways Forward for Scandinavia & the Baltic States","authors":"Stina Andersson","doi":"10.4103/jras.jras_84_23","DOIUrl":"https://doi.org/10.4103/jras.jras_84_23","url":null,"abstract":"","PeriodicalId":394246,"journal":{"name":"Journal of Research in Ayurvedic Sciences","volume":"192 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131773049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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